National Library of Energy BETA

Sample records for appl biochem biotechnol

  1. Sketch Retrieval via Dense Stroke Features bottle apple apple apple apple apple swan giraffe mug giraffe giraffe giraffe

    E-Print Network [OSTI]

    Yang, Ming-Hsuan

    Sketch Retrieval via Dense Stroke Features bottle apple apple apple apple apple swan giraffe mug giraffe giraffe giraffe bottle swan giraffe swan swan swan swan apple apple apple apple bottle bottle swan

  2. COBIOT-591; NO OF PAGES 8 Please cite this article in press as: Xia Z, Rao J. Biosensing and imaging based on bioluminescence resonance energy transfer, Curr Opin Biotechnol (2009), doi:10.1016/j.copbio.2009.01.001

    E-Print Network [OSTI]

    Rao, Jianghong

    2009-01-01

    and imaging based on bioluminescence resonance energy transfer, Curr Opin Biotechnol (2009), doi:10.1016/j resonance energy transfer Zuyong Xia and Jianghong Rao Bioluminescence resonance energy transfer (BRET) operates with biochemical energy generated by bioluminescent proteins to excite fluorophores and offers

  3. Kiss Apple

    E-Print Network [OSTI]

    Hacker, Randi; Boyd, David

    2011-08-24

    the tiny kiss apple. Apples are known to be natural breath fresheners but chomping down on an after dinner regulation size fruit could ruin the romantic mood. Hence the kiss apple. The ping-pong ball sized fruit can be popped in the mouth whole. Not content...

  4. Appl Microbiol Biotechnol (2004) 66: 166173 DOI 10.1007/s00253-004-1666-7

    E-Print Network [OSTI]

    2004-01-01

    was to characterize bacterial communities in the reactor operated under two different hydraulic retention times (HRTs The recent surge in H2 production research promises to make this clean fuel an important part of the energy were performed under aseptic conditions and reported H2 recoveries between 1.1 mol H2/mol glucose and 2

  5. Appl Microbiol Biotechnol (2006) 72: 745755 DOI 10.1007/s00253-005-0302-5

    E-Print Network [OSTI]

    Sinskey, Anthony J.

    2006-01-01

    aldehyde was an inter- mediate of eugenol degradation by I24. Since the genome sequence of I24 is devoid, and Mycobacterium (Bell et al. 1998; Goodfellow et al. 1998). Since many Rhodococcus species are able to degrade-allyl-2-methoxy- phenol), ferulic acid (4-hydroxy-3-methoxycinnamate), and lignin (Chen et al. 1982

  6. Appl Microbiol Biotechnol (2005) 67: 412419 DOI 10.1007/s00253-004-1788-y

    E-Print Network [OSTI]

    Tiquia-Arashiro, Sonia M.

    2005-01-01

    as N fertilizer. Animal waste composts have been used as a nutrient source in crop production (Dick utilization of animal wastes, including poultry wastes, via composting (Tiquia 2002). During composting. Bacterial community profiles on feathers during composting as determined by terminal restriction fragment

  7. Comparing Apples to Apples: Benchmarking Electrocatalysts for...

    Office of Science (SC) Website

    Ave., SW Washington, DC 20585 P: (301) 903-3081 F: (301) 903-6594 E: Email Us More Information May 2015 Comparing Apples to Apples: Benchmarking Electrocatalysts for...

  8. Appl Microbiol Biotechnol (2003) 61:6168 DOI 10.1007/s00253-002-1191-5

    E-Print Network [OSTI]

    Sinskey, Anthony J.

    2003-01-01

    production in Corynebacterium glutamicum. Gene ex- pression changes during C. glutamicum fermentations were Corynebacterium glutamicum is used in the commercial production of amino acids, primarily glutamic acid and lysine

  9. Apple Trees for Every Garden

    E-Print Network [OSTI]

    Martin, Orin

    2008-01-01

    Grower Press. Organic Apple Production Manual. Publication #of dwarf and semi-dwarf apple varieties can be seen in theGardener Apple Trees for Every Garden Orin Martin manages

  10. Cynthia Sandberg: Love Apple Farm

    E-Print Network [OSTI]

    Rabkin, Sarah

    2010-01-01

    me about the name, Love Apple Farm. Where does that comegrowbetterveggies/about-love-apple-farm.html See http://Photo by Tana Butler Love Apple Farm Cynthia Sandberg is

  11. AIDP -Apple Interface Design Project

    E-Print Network [OSTI]

    Tollmar, Konrad

    AIDP - Apple Interface Design Project AIDP - Apple Interface Design Project m 92-95 m Joy Mountford m Design Centre, Advanced Technology Group m Apple's Industrial Design Group "Encourage ProjectThe Project m Bridge the gulf between the physical and virtual worlds - Apple m Design a new way

  12. Reflectivematerials enhance `Fuji'apple

    E-Print Network [OSTI]

    Crisosto, Carlos H.

    Reflectivematerials enhance `Fuji'apple color Harry Andris o Carlos H. Crisosto Red color developmentis an important factor for consumer acceptance of California 'Fuji' apples. Several attempts to im not affect fla- vor, it is an important factor for con- sumer acceptance of apples. Cyanidin is the immediate

  13. About APPLE II Operation

    SciTech Connect (OSTI)

    Schmidt, T.; Zimoch, D.

    2007-01-19

    The operation of an APPLE II based undulator beamline with all its polarization states (linear horizontal and vertical, circular and elliptical, and continous variation of the linear vector) requires an effective description allowing an automated calculation of gap and shift parameter as function of energy and operation mode. The extension of the linear polarization range from 0 to 180 deg. requires 4 shiftable magnet arrrays, permitting use of the APU (adjustable phase undulator) concept. Studies for a pure fixed gap APPLE II for the SLS revealed surprising symmetries between circular and linear polarization modes allowing for simplified operation. A semi-analytical model covering all types of APPLE II and its implementation will be presented.

  14. Apple Strength Issues

    SciTech Connect (OSTI)

    Syn, C

    2009-12-22

    Strength of the apple parts has been noticed to decrease, especially those installed by the new induction heating system since the LEP campaign started. Fig. 1 shows the ultimate tensile strength (UTS), yield strength (YS), and elongation of the installed or installation-simulated apples on various systems. One can clearly see the mean values of UTS and YS of the post-LEP parts decreased by about 8 ksi and 6 ksi respectively from those of the pre-LEP parts. The slight increase in elongation seen in Fig.1 can be understood from the weak inverse relationship between the strength and elongation in metals. Fig.2 shows the weak correlation between the YS and elongation of the parts listed in Fig. 1. Strength data listed in Figure 1 were re-plotted as histograms in Figs. 3 and 4. Figs. 3a and 4a show histograms of all UTS and YS data. Figs. 3b and 4b shows histograms of pre-LEP data and Figs. 3c and 4c of post-LEP data. Data on statistical scatter of tensile strengths have been rarely published by material suppliers. Instead, only the minimum 'guaranteed' strength data are typically presented. An example of strength distribution of aluminum 7075-T6 sheet material, listed in Fig. 5, show that its scatter width of both UTS and YS for a single sheet can be about 6 ksi and for multi-lot scatter can be as large as 11 ksi even though the sheets have been produced through well-controlled manufacturing process. By approximating the histograms shown in Figs. 3 and 4 by a Gaussian or similar type of distribution curves, one can plausibly see the strength reductions in the later or more recent apples. The pre-LEP data in Figs. 3b and 4b show wider scatter than the post-LEP data in Figs. 3c and 4c and seem to follow the binomial distribution of strength indicating that the apples might have been made from two different lots of material, either from two different vendors or from two different melts of perhaps slightly different chemical composition by a single vendor. The post-LEP apples seem to have been from a single batch of material. The pre-LEP apples of the weak strength and the post-LEP apples with even weaker strength could have been made of the same batch of material, and the small strength differential might be due to the difference in the induction heating system. If the pre-LEP apples with the lower strength and the post LEP apples are made from the same batch of material, their combined scatter of strength data would be wider and can be understood as a result of the additional processing steps of stress relief and induction heating as discussed.

  15. Century Learning through Apple Technology

    E-Print Network [OSTI]

    21st Century Learning through Apple Technology July 4 ­ 5, 2013 This exciting institute will appeal to educators who wish to enhance their teaching in support of 21st century learning using Apple technology. This institute begins with a keynote address that looks at how new technologies can enhance 21st century learning

  16. Apple Closeout Prices unh computer store

    E-Print Network [OSTI]

    Apple Closeout Prices 6/5/15 unh computer store university of new hampshire phone: (603) 862 and battery life.1 Key Features MacBook Pro with Retina display (13-inch) AppleCare for MacBook Pro Apple Compared with the previous-generation. 2 Battery life varies by use and configuration. See www.apple

  17. Fungicide control of apple scab: 2010 field trial

    E-Print Network [OSTI]

    Eynard, James; Wunderlich, Lynn; Gubler, W D

    2010-01-01

    communications. 2010 Apple scab field trial, Department ofduring leaf fall to control apple scab (Venturia inaequalis)mixtures on scab control in apple orchards. Plant Pathology

  18. Potential of Mineral Uptake Efficiency by Some Apple Rootstocks

    E-Print Network [OSTI]

    Amiri, Mohammad E; Fallahi, Esmail

    2009-01-01

    1999. Drought tolerance of apple rootstocks: Production andwater relations of five apple rootstocks. Acta Horticultureon Mineral Composition of Apple Leaves. J. Am. Soc. Hort.

  19. Biochemical transformation of coals

    DOE Patents [OSTI]

    Lin, Mow S. (Rocky Point, NY); Premuzic, Eugene T. (East Moriches, NY)

    1999-03-23

    A method of biochemically transforming macromolecular compounds found in solid carbonaceous materials, such as coal is provided. The preparation of new microorganisms, metabolically weaned through challenge growth processes to biochemically transform solid carbonaceous materials at extreme temperatures, pressures, pH, salt and toxic metal concentrations is also disclosed.

  20. Biochemical transformation of coals

    DOE Patents [OSTI]

    Lin, M.S.; Premuzic, E.T.

    1999-03-23

    A method of biochemically transforming macromolecular compounds found in solid carbonaceous materials, such as coal is provided. The preparation of new microorganisms, metabolically weaned through challenge growth processes to biochemically transform solid carbonaceous materials at extreme temperatures, pressures, pH, salt and toxic metal concentrations is also disclosed. 7 figs.

  1. Did Apple’s refusal to license proprietary information enabling interoperability with its iPod music player constitute an abuse under Article 82 of the EC Treaty?

    E-Print Network [OSTI]

    Mazziotti, Giuseppe

    2005-01-01

    Did Apple’s refusal to license proprietary informationtechnology that allowed Apple, as the creator of amises en œuvre par la société Apple Computer, Inc. dans les

  2. Fire blight of apple blossoms Fireblight of apples and pears, caused by the

    E-Print Network [OSTI]

    Fire blight of apple blossoms Fireblight of apples and pears, caused by the bacterium Erwinia. W. Lightner. 1990. Predicting apple blossom infections by Erwinia amylovora using the Maryblyt model for forecasting fire blight disease in apples and pears. University of Maryland, College Park, MD. #12;

  3. Connecting your Apple to Octopus 7600's

    SciTech Connect (OSTI)

    Barton, G.W. Jr.

    1983-01-17

    In UCID-19588, Communicating between the Apple and the Wang, we described how to take Apple DOS text files and send them to the Wang, and how to return Wang files to the Apple. It is also possible to use your Apple as an Octopus terminal, and to exchange files with Octopus 7600's. Presumably, you can also talk to the Crays, or any other part of the system. This connection has another virtue. It eliminates one of the terminals in your office.

  4. Feasibility of utilizing apple pomace

    SciTech Connect (OSTI)

    Stapleton, J.

    1983-06-01

    Apple pomace, the solid residue from juice production, is a solid waste problem in the Hudson Valley. This study investigates possibilities for converting it to a resource. The characteristics of the region's apple growing and processing industries are examined at length, including their potential for converting waste biomass. The properties of apple pomace are described. From interviews with Hudson Valley apple processors the following information is presented: quantities of pomace produced; seasonality of production; disposal procedures, costs, and revenues; trends in juice production; and attitudes toward alternatives. Literature research resulted in a list of more than 25 end uses for apple pomace of which eight were selected for analysis. Landfilling, landspreading, composting, animal feed, direct burning, gasification, anaerobic digestion (methane generation), and fermentation (ethanol production) were analyzed with regard to technical availability, regulatory and environmental impact, attitudes toward end use, and energetic and economic feasibility (See Table 19). The study recommends (1) a pilot anaerobic digestion plant be set up, (2) the possibility of extracting methane from the Marlborough landfill be investigated, (3) a study of the mid-Hudson waste conversion potential be conducted, and (4) an education program in alternative waste management be carried out for the region's industrial and agricultural managers.

  5. Energy accounting of apple processing operations

    SciTech Connect (OSTI)

    Romero, R.; Singh, R.P.; Brown, D.

    1981-01-01

    A thermal-energy accounting study was conducted at an apple processing plant. An analysis is given of thermal energy use and thermal efficiencies of an apple-juice single-effect evaporator and an apple-sauce cooker. 3 refs.

  6. Biochemical upgrading of oils

    DOE Patents [OSTI]

    Premuzic, Eugene T. (East Moriches, NY); Lin, Mow S. (Rocky Point, NY)

    1999-01-12

    A process for biochemical conversion of heavy crude oils is provided. The process includes contacting heavy crude oils with adapted biocatalysts. The resulting upgraded oil shows, a relative increase in saturated hydrocarbons, emulsions and oxygenates and a decrease in compounds containing in organic sulfur, organic nitrogen and trace metals. Adapted microorganisms which have been modified under challenged growth processes are also disclosed.

  7. Biochemical upgrading of oils

    DOE Patents [OSTI]

    Premuzic, E.T.; Lin, M.S.

    1999-01-12

    A process for biochemical conversion of heavy crude oils is provided. The process includes contacting heavy crude oils with adapted biocatalysts. The resulting upgraded oil shows, a relative increase in saturated hydrocarbons, emulsions and oxygenates and a decrease in compounds containing organic sulfur, organic nitrogen and trace metals. Adapted microorganisms which have been modified under challenged growth processes are also disclosed. 121 figs.

  8. Jonathan Altamirano Biochem 118

    E-Print Network [OSTI]

    Brutlag, Doug

    in Breast/Ovarian Cancer Mutation carriers= x3.5 chance 16% patients with 3+ relatives with germ Prostate Cancer: OR=1.45 Lymphoma: OR=2.83 Liver Cancer Colon Cancer Breast Cancer Ovarian CancerJonathan Altamirano Biochem 118 03/15/12 #12;Pancreatic Cancer Uncontrolled cell growth

  9. agbioresearch.msu.edu MSU Fruit Team Apple Maturity Report

    E-Print Network [OSTI]

    1 agbioresearch.msu.edu MSU Fruit Team Apple Maturity Report Northwest Region Reports - 2009 Michigan Apple Research Committee Michigan Apple Shippers MSU Extension MSU AgBioResearch NW MICHIGAN APPLE MATURITY REPORT #1 September 16, 2009 General Comments - This year the NWMHRS will be testing apples

  10. agbioresearch.msu.edu MSU Fruit Team Apple Maturity Report

    E-Print Network [OSTI]

    1 agbioresearch.msu.edu MSU Fruit Team Apple Maturity Report Northwest Region Reports - 2007 Nikki Horticulture Society Michigan Apple Research Committee Michigan apple Shippers MSU Extension MSU Ag Pome Fruit Code-a-phone/Apple Maturity Line (231) 947-3063 NW MICHIGAN APPLE MATURITY REPORT #1 August

  11. Fruit Preparation Apples Select crisp and firm apples. Wash, peel and core. Slice medium apples

    E-Print Network [OSTI]

    New Hampshire, University of

    quart of fruit. Package, leaving head space,** seal, label and freeze. Pears Wash, peel and core. Slice whole strawberries and mix. Let stand 15 minutes. Package, leaving head space.** Seal, label, and freeze the sugar. Treated apple slices can also be frozen on a tray and then packed. Package, leaving head space

  12. Automated audiometry using Apple iOS-based application technology

    E-Print Network [OSTI]

    Foulad, A; Bui, P; Djalilian, H

    2013-01-01

    Automated Audiometry Using Apple iOS-Based ApplicationAutomated Audiometry Using Apple iOS-Based Applicationthe feasibility of an Apple iOS-based automated hearing

  13. Apple Computer: The iCEO Seizes the Internet

    E-Print Network [OSTI]

    West, Joel

    2002-01-01

    sales. Table 3: Milestones in Apple direct online retailingDate Event mid-1994 Apple launches first web site Nov. 19971998 Sept. 1998 Jan. 1999 Apple Store (U.S. ) opens; first

  14. Fungicide control of apple scab: 2007 trial results

    E-Print Network [OSTI]

    Janousek, Christopher N; Lorber, Jacob D; Wunderlich, Lynn; Gubler, W D

    2010-01-01

    from Adaskaveg et al. (2007). Apple trial, 2007. W.D. Gublerpp. MacHardy, W.E. 1996. Apple Scab. Biology, Epidemiology,Pest Management for Apples & Pears. 2 nd ed. University of

  15. Instructions for Apple Leaf Sample Collection.doc September 2013 Instructions for Apple Leaf Sample Collection Vermont

    E-Print Network [OSTI]

    Hayden, Nancy J.

    Instructions for Apple Leaf Sample Collection.doc September 2013 Instructions for Apple Leaf Sample;Instructions for Apple Leaf Sample Collection.doc September 2013 Washing Leaf Samples 1. Wash the leaf samples

  16. Apple Harvest Time! Determining when apples are ready to be harvested can be tricky. You need to know the variety of the apple and its approximate harvest

    E-Print Network [OSTI]

    New Hampshire, University of

    Apple Harvest Time! Determining when apples are ready to be harvested can be tricky. You need to know the variety of the apple and its approximate harvest date. These dates vary each year with fluctuations in blooming rates, degree days and rainfall. If you're growing your own apples, perhaps the best

  17. Production of alcohol from apple pomace

    SciTech Connect (OSTI)

    Hang, Y.D.; Lee, C.Y.; Woodams, E.E.; Cooley, H.J.

    1981-12-01

    Production of ethyl alcohol from apple pomace with a Montrachet strain of Saccharomyces cerevisiae is described. More than 43 grams of the ethyl alcohol could be produced per kg of apple pomace fermented at 30 degrees Celcius in 24 hours. The fermentation efficiency of this process was approximately 89%. (Refs. 9).

  18. Low energy electron irradiation of an apple 

    E-Print Network [OSTI]

    Brescia, Giovanni Batista

    2002-01-01

    simulation. A software package, MCNP (Monte Carlo N-Particle), was used to simulate an electron beam irradiation with a 1.0, 1.5 and 2.0 MeV sources on an apple modeled by interconnecting two spheres. The apple radii were 4.4 cm (perpendicular to its axis...

  19. Michigan Apple Committee Research Priorities for 2014/15

    E-Print Network [OSTI]

    Michigan Apple Committee Research Priorities for 2014/15 Following are the 2014/15 priorities of the Michigan Apple Committee. (In priority order.) 1. Increase demand To conduct consumer related research that will help sell Michigan Apples more profitably. a. Market research b. Value ­ convenience, apples versus

  20. Michigan Apple Committee 2014/15 Request for Proposals

    E-Print Network [OSTI]

    1 Michigan Apple Committee 2014/15 Request for Proposals The Michigan Apple Committee (MAC the profitability of apple growing through improving production information and techniques; developing new markets subcommittee established the following as its charter in early 2009: To help the Michigan Apple Committee

  1. agbioresearch.msu.edu MSU Fruit Team Apple Maturity Report

    E-Print Network [OSTI]

    1 agbioresearch.msu.edu MSU Fruit Team Apple Maturity Report Northwest Region Reports - 2005 Jim Project GREEEN Michigan State Horticulture Society Michigan Apple Research Committee Michigan apple sites: www.ams.usda.gov/marketnews.htm www.bhfm.com NW Michigan Pome Fruit Code-a-phone/Apple Maturity

  2. agbioresearch.msu.edu MSU Fruit Team Apple Maturity Report

    E-Print Network [OSTI]

    1 agbioresearch.msu.edu MSU Fruit Team Apple Maturity Report Northwest Region Reports - 2008 Michigan Apple Research Committee Michigan apple Shippers MSU Extension MSU AgBioResearch Current pricing information can be obtained at the following web sites: http://www.bhfm.com/ NW Michigan Pome Fruit Code-a-phone/Apple

  3. SW MICHIGAN APPLE MATURITY REPORT ISSUE 1 August 25, 2010

    E-Print Network [OSTI]

    SW MICHIGAN APPLE MATURITY REPORT ISSUE 1 ­ August 25, 2010 Bill Shane, Diane Brown-Rytlewski, and Mark Longstroth Michigan State University This is the first of weekly apple maturity report for SW. See the Michigan State University apple web site (apples.msu.edu) for more information, including

  4. SW MICHIGAN APPLE MATURITY REPORT ISSUE 2 August 31, 2010

    E-Print Network [OSTI]

    SW MICHIGAN APPLE MATURITY REPORT ISSUE 2 ­ August 31, 2010 Bill Shane, Diane Brown-Rytlewski, and Mark Longstroth Michigan State University This is the first of weekly apple maturity report for SW. See the Michigan State University apple web site (apples.msu.edu) for more information, including

  5. agbioresearch.msu.edu MSU Fruit Team Apple Maturity Report

    E-Print Network [OSTI]

    1 agbioresearch.msu.edu MSU Fruit Team Apple Maturity Report Northwest Region Reports - 2006 Jim Project GREEEN Michigan State Horticulture Society Michigan Apple Research Committee Michigan apple sites: www.ams.usda.gov/marketnews.htm www.bhfm.com NW Michigan Pome Fruit Code-a-phone/Apple Maturity

  6. Synthetic and organic fungicide control of apple scab: 2009 field trial

    E-Print Network [OSTI]

    Janousek, Christopher N; Bay, Ian S; Gubler, W. Douglas

    2009-01-01

    during leaf fall to control apple scab (Venturia inaequalis)mixtures on scab control in apple orchards. Plant Pathologyscab development in an organic apple orchard. Agriculture,

  7. EFFECT OF TWO ROOTSTOCK SELECTIONS ON THE SEASONAL NUTRITIONAL VARIABILITY OF BRAEBURN APPLE

    E-Print Network [OSTI]

    Hirzel, Juan Fernando; Best, Stanley

    2009-01-01

    potasium and magnesium into apple fruit in high densityof Golden delicious apple trees. Acta Horticulturae 448:107-in leaves of different apple rootstocks and Elise Scion

  8. Abiotic and biotic factors affecting light brown apple moth, Epiphyas postvittana, in California

    E-Print Network [OSTI]

    Buergi, Linda Patricia

    2012-01-01

    mortality of lightbrown apple moth. In: O’Callaghan, M. (tryoni and the light brown apple moth Epiphyas postvittanaof the light brown apple moth, Epiphyas postvittana (

  9. Technical Market Analysis for Biochemical Conversion Presentation...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Technical Market Analysis for Biochemical Conversion March 23, 2015 Biochemical Conversion Jim Collett and Mark Butcher PNNL This presentation does not contain any proprietary,...

  10. Specificity and completion time distributions of biochemical...

    Office of Scientific and Technical Information (OSTI)

    order to produce specific complex structures from a large set of similar biochemical building blocks, many biochemical systems require high sensitivity to small molecular...

  11. Ergonomic evaluation of the Apple Adjustable Keyboard

    SciTech Connect (OSTI)

    Tittiranonda, P.; Burastero, S.; Shih, M.; Rempel, D.

    1994-05-01

    This study presents an evaluation of the Apple Adjustable Keyboard based on subjective preference and observed joint angles during typing. Thirty five keyboard users were asked to use the Apple adjustable keyboard for 7--14 days and rate the various characteristics of the keyboard. Our findings suggest that the most preferred opening angles range from 11--20{degree}. The mean ulnar deviation on the Apple Adjustable keyboard is 11{degree}, compared to 16{degree} on the standard keyboard. The mean extension was decreased from 24{degree} to 16{degree} when using the adjustable keyboard. When asked to subjectively rate the adjustable keyboard in comparison to the standard, the average subject felt that the Apple Adjustable Keyboard was more comfortable and easier to use than the standard flat keyboard.

  12. Biomass Program 2007 Accomplishments - Biochemical Conversion Platform

    SciTech Connect (OSTI)

    none,

    2009-10-27

    This document details accomplishments of the Biomass Program Biochemical Conversion Platform accomplishments in 2007.

  13. Biochemical Conversion Pilot Plant (Fact Sheet)

    SciTech Connect (OSTI)

    Not Available

    2012-06-01

    This fact sheet provides information about Biochemical Conversion Pilot Plant capabilities and resources at NREL.

  14. Production of fuels and chemicals from apple pomace

    SciTech Connect (OSTI)

    Hang, Y.D.

    1987-03-01

    Nearly 36 million tons of apples are produced annually in the US. Approximately 45% of the total US apple production is used for processing purposes. The primary by-product of apple processing is apple pomace. It consists of the presscake resulting from pressing apples for juice or cider, including the presscake obtained in pressing peel and core wastes generated in the manufacture of apple sauce or slices. More than 500 food processing plants in the US produce a total of about 1.3 million metric tons of apple pomace each year, and it is likely that annual disposal fees exceed $10 million. Apple pomace has the potential to be used for the production of fuels (ethanol and biogas containing 60% methane) and food-grade chemicals. These uses will be reviewed in this article.

  15. SW MICHIGAN APPLE MATURITY REPORT ISSUE 3 September 7, 2010

    E-Print Network [OSTI]

    SW MICHIGAN APPLE MATURITY REPORT ISSUE 3 ­ September 7, 2010 Bill Shane, Diane Brown like to have samples from your farm tested for maturity. See the Michigan State University apple web site (apples.msu.edu) for more information, including reports from other regions, past season reports

  16. MSU Fruit Team 2012 Apple Maturity Report Northwest Region Reports

    E-Print Network [OSTI]

    1 MSU Fruit Team 2012 Apple Maturity Report Northwest Region Reports During the harvest season, apples from different regions are collected for maturity testing. The data is then compiled by MSU Extension educators into recommendations for harvest and storage of the most commonly grown apple varieties

  17. MSU Fruit Team 2011 Apple Maturity Report Northwest Region Reports

    E-Print Network [OSTI]

    1 MSU Fruit Team 2011 Apple Maturity Report Northwest Region Reports During the harvest season, apples from different regions are collected for maturity testing. The data is then compiled by MSU Extension educators into recommendations for harvest and storage of the most commonly grown apple varieties

  18. MSU Fruit Team 2010 Apple Maturity Report Northwest Region Reports

    E-Print Network [OSTI]

    1 MSU Fruit Team 2010 Apple Maturity Report Northwest Region Reports During the harvest season, apples from different regions are collected for maturity testing. The data is then compiled by MSU Extension educators into recommendations for harvest and storage of the most commonly grown apple varieties

  19. Crabapples Resistant to Apple Scab and Japanese Beetle in Indiana

    E-Print Network [OSTI]

    Pittendrigh, Barry

    Crabapples Resistant to Apple Scab and Japanese Beetle in Indiana Cliff Sadof, Department pests, apple scab and Japanese beetle, have also given this plant a reputation of being prone to insect and disease problems. Both these pests are widely distributed in Indiana. Apple scab is a fungal disease

  20. APPLE ROOTSTOCKS COMPARISON CHART v. 1 Jessica Lyga,

    E-Print Network [OSTI]

    Chen, Tsuhan

    GENEVA® APPLE ROOTSTOCKS COMPARISON CHART v. 1 Contact: Jessica Lyga, Plant Varieties & Germplasm University and United States Department of Agriculture-Agricultural Research Service (USDA- ARS) Apple, resistance to the soil pathogens of the sub-temperate regions of the US, and tolerance to apple replant

  1. Apple Maturity Protocol Tests for apple flesh firmness and starch conversion are important tools for monitoring crop

    E-Print Network [OSTI]

    Apple Maturity Protocol Tests for apple flesh firmness and starch conversion are important tools dissolved. A magnetic stir plate with a plastic coated stir bar works well. Add 2.2 grams of iodine crystals the solution on the cut surface of an immature apple. Dip the cut surface for a second or two. It should stain

  2. Financing Advanced Biofuels, Biochemicals And Biopower In Integrated...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Financing Advanced Biofuels, Biochemicals And Biopower In Integrated Biorefineries Financing Advanced Biofuels, Biochemicals And Biopower In Integrated Biorefineries Afternoon...

  3. Communicating between the Apple and the Wang

    SciTech Connect (OSTI)

    Barton, G.W., Downey, R.

    1982-10-26

    This manual covers what the beginner needs to know in order to transfer files between an Apple's Microcomputer and a Wang's OIS Word Processor. We have also tried to indicate where the experienced user might want to look for additional details. We cover the use of Apple Writer )(, VisiTerm, VisiCalc, and EasyWriter Professional. For us, the two most useful connections are from Applewriter to Wang and from Visicalc to Wang. From Wang to Apple Writer via Visiterm may have some value. Files can be transferred by VisiTerm to Wang, but they arrive with RETURNS in the middle of words, which have to be edited out, so we do not recommend it. We describe how to go from EasyWriter to Wang, but we do not know how to go from Wang to EasyWriter. We see no reason to go from Wang to VisiCalc, so we haven't thought about it. All instructions are given for a typical configuration of the Apple, namely the one on which this manual was composed. It is detailed in the section on Hardware and Software.

  4. V-164: Apple QuickTime Multiple Flaws Let Remote Users Execute...

    Broader source: Energy.gov (indexed) [DOE]

    Apple QuickTime Multiple Flaws Let Remote Users Execute Arbitrary Code PLATFORM: Apple QuickTime prior to 7.7.4. ABSTRACT: Apple QuickTime Multiple Vulnerabilities REFERENCE LINKS:...

  5. Light brown apple moth’s arrival in California worries commodity groups

    E-Print Network [OSTI]

    Varela, Lucia G.; Johnson, Marshall W; Strand, Larry; Wilen, Cheryl A; Pickel, Carolyn

    2008-01-01

    control of light brown apple moth, Epi- phyas postvittana (2007a. Light brown apple moth host list. www.cdfa.ca.gov/p. CDFA. 2007b. Light brown apple moth project: Advisories.

  6. Impact of Foliar Fertilizer Containing Iodine on “Golden Delicious” Apple Trees

    E-Print Network [OSTI]

    Szwonek, Eugeniusz

    2009-01-01

    on marketable Golden Delicious/M.9 apple production. At thecontaining fertilizer on apple fruits firmness and theirold “Golden Delicious/M.9” apple trees Trees were spaced at

  7. New Zealand lessons may aid efforts to control light brown apple moth in California

    E-Print Network [OSTI]

    Varela, Lucia G.; Walker, James T.S.; Lo, Peter L; Rogers, David J

    2010-01-01

    1975. Integrated control of apple pests in New Zealand. 1.of the light brown apple moth Epiphyas postvittana (Walker),685–92. Dumbleton L J. 1932. The apple leaf-roller (Tortrix

  8. Why the Apple Doesn’t Fall Far: Understanding Intergenerational Transmission of Human Capital

    E-Print Network [OSTI]

    Black, Sandra; Devereux, Paul; Salvanes, Kjell

    2004-01-01

    Kjell G. Salvanes. 2003. “Why the Apple Doesn’t Fall Far:Why the Apple Doesn't Fall Far: UnderstandingPaper Series Why the Apple Doesn’t Fall Far: Understanding

  9. Apple Burrknot Borers in New York Revisited Pest status and chemical control of borers infesting apple burrknots in New York State

    E-Print Network [OSTI]

    Agnello, Arthur M.

    Apple Burrknot Borers in New York ­ Revisited Pest status and chemical control of borers infesting apple burrknots in New York State DAVID P. KAIN, RICHARD W. STRAUB AND ARTHUR M. AGNELLO Department damage to dwarf apple trees caused by American plum borer, a survey was conducted in the major apple

  10. The Atom and the Apple, Princeton University Press, "The Atom and the Apple is a delightful ramble through many areas of science as well as

    E-Print Network [OSTI]

    Balibar, Sébastien

    The Atom and the Apple, Princeton University Press, Reviews: "The Atom and the Apple and stimulating, and it frequently challenges political correctness. . . . The Atom and the Apple provides." --Publishers Weekly (Starred Review) #12;Science Teacher Association recommends : The Atom and the Apple

  11. T-673: Apple Safari Multiple Flaws Let Remote Users Execute Arbitrary...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    3: Apple Safari Multiple Flaws Let Remote Users Execute Arbitrary Code, Conduct Cross-Site Scripting Attacks T-673: Apple Safari Multiple Flaws Let Remote Users Execute Arbitrary...

  12. Computing Resources at Chemical and Biochemical Engineering

    E-Print Network [OSTI]

    Muzzio, Fernando J.

    Computing Resources at Chemical and Biochemical Engineering Note that use of all Rutgers University) consists of 18 Windows NT Workstations and is primarily reserved for classroom use for Chemical Engineering at Chemical and Biochemical Engineering. DSV Lab. The DSV lab consists of 60 Sun UltraSparc 10 computers. Each

  13. Biochemical transformation of solid carbonaceous material

    DOE Patents [OSTI]

    Lin, Mow S. (Rocky Point, NY); Premuzic, Eugene T. (East Moriches, NY)

    2001-09-25

    A method of biochemically transforming macromolecular compounds found in solid carbonaceous materials, such as coal is provided. The preparation of new microorganisms, metabolically weaned through challenge growth processes to biochemically transform solid carbonaceous materials at extreme temperatures, pressures, pH, salt and toxic metal concentrations is also disclosed.

  14. Handleiding eduroam op Apple iOS6

    E-Print Network [OSTI]

    Handleiding eduroam op Apple iOS6 Version: 1.0 eduroam Date: 24-04-2013 #12;2 Inleiding Deze handleiding beschrijft hoe u met uw Apple iPad of iPhone met iOS6 een verbinding met eduroam kan opzetten

  15. A structured approach for the engineering of biochemical network

    E-Print Network [OSTI]

    Breitling, Rainer

    . Keywords: systems biology; biochemical networks; modelling; signal transduction; Petri nets; ordinaryA structured approach for the engineering of biochemical network models, illustrated for signalling; Received (in revised form): 2nd May 2008 Abstract Quantitative models of biochemical networks (signal

  16. Multiple locus genealogies and phenotypic characters reappraise the causal agents of apple ring rot in China

    E-Print Network [OSTI]

    Biggs, Alan R.

    Multiple locus genealogies and phenotypic characters reappraise the causal agents of apple ring rot # School of Science 2014 Abstract Apple ring rot inflicts severe economic losses in the main apple phylogenetic species recognition (GCPSR) was applied to pathogenic fungal isolates from apple and pear from

  17. Who Captures Value in a Global Innovation System? The case of Apple's iPod

    E-Print Network [OSTI]

    Linden, Greg; Kraemer, Kenneth L; Dedrick, Jason

    2007-01-01

    Portelligent Inc. (2006). Apple iPod Video, 30GB MultimediaSystem? The case of Apple's iPod Greg Linden, Kenneth L.to look at one member of Apple’s iPod family, part of a

  18. 7.5 Declaration in Apple vs. Microsoft/Hewlett-Packard

    E-Print Network [OSTI]

    Shneiderman, Ben

    327 7.5 Declaration in Apple vs. Microsoft/Hewlett-Packard Ben Shneiderman I, Ben Shneiderman declarations and to further identify the arrangement that is unique to Apple and that makes the overall Petrie, Attorneys for Plaintiff, Apple Computer, Inc.; APPLE COMPUTER, INC., Plaintiff, vs. MCROSOFT CORP

  19. Apple watch: has its time come? Charles Arthur for guardian.co.uk

    E-Print Network [OSTI]

    South Bohemia, University of

    Apple watch: has its time come? Charles Arthur for guardian.co.uk Apple's next big thing will be a "smart watch" which will "fill a gaping hole in the Apple ecosystem" ­ at least according to one already being worked on inside Apple. With the company being sued by Greenlight Capital for hoarding its

  20. Dimer Dissociation and Unfolding Mechanism of Coagulation Factor XI Apple 4 Domain: Spectroscopic

    E-Print Network [OSTI]

    Roder, Heinrich

    Dimer Dissociation and Unfolding Mechanism of Coagulation Factor XI Apple 4 Domain: Spectroscopic of disulfide- linked chains each containing four apple domains and a catalytic domain. The apple 4 domain (A4; A4, apple 4 domain of factor XI; DLS, dynamic light scattering; FXI, factor XI; FXIa, factor FXIa

  1. MSU Fruit Team Apple Maturity Report 2014 Northwest Region, Report Number 5: October 8, 2014

    E-Print Network [OSTI]

    MSU Fruit Team Apple Maturity Report 2014 Northwest Region, Report Number 5: October 8, 2014 Nikki Rothwell and Emily Pochubay, Extension Fruit Educators Wet conditions have slowed apple harvest are not cooperating with northwest Michigan apple growers as many apples are ripening quicker this week, but rain has

  2. Historical Perspectives on Apple Production: Fruit Tree Pest Management, Regulation and

    E-Print Network [OSTI]

    Jentsch, Peter J.

    2 Historical Perspectives on Apple Production: Fruit Tree Pest Management, Regulation and New. Historical Use of Pesticides in Apple Production Overview of Apple Production and Pest Management Prior in Apple Production Chemical Residues in Early Insect Management Historical Chemical Regulation Recent

  3. Evaluation of Pest Management Tactics for Organic Apple Production A. Agnello, H. Reissig, and D. Combs

    E-Print Network [OSTI]

    Agnello, Arthur M.

    Evaluation of Pest Management Tactics for Organic Apple Production A. Agnello, H. Reissig, and D number of both native and introduced insect and mite species attack apples grown in commercial apple orchards. Control of this pest complex is particularly challenging, because unlike the more arid apple

  4. 2015 Peer Review Presentations-Biochemical Conversion | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Biochemical Conversion 2015 Peer Review Presentations-Biochemical Conversion The Bioenergy Technologies Office hosted its 2015 Project Peer Review on March 23-27, 2015, at the...

  5. Process Design and Economics for Biochemical Conversion of Lignocellul...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Biochemical Conversion of Lignocellulosic Biomass to Ethanol: Dilute-Acid Pretreatment and Enzymatic Hydrolysis of Corn Stover Process Design and Economics for Biochemical...

  6. 2011 Biomass Program Platform Peer Review: Biochemical Conversion...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Biochemical Conversion 2011 Biomass Program Platform Peer Review: Biochemical Conversion This document summarizes the recommendations and evaluations provided by an independent...

  7. Simultaneous consumption of pentose and hexose sugars: an optimal microbial phenotype for efficient fermentation of lignocellulosic biomass

    E-Print Network [OSTI]

    Kim, Jae-Han; Block, David E.; Mills, David A.

    2010-01-01

    Morel et al. 1999; Schick et al. 1999). The regulatoryBiochem Biotechnol 28– Schick J, Weber B, Klein JR, Henrich

  8. Blake Farms is a diversified apple orchard, offering U-pick apples and farm stand sales in the fall, as well as a growing business making and selling hard cider. Our goal is to provide quality

    E-Print Network [OSTI]

    Isaacs, Rufus

    Overview Blake Farms is a diversified apple orchard, offering U-pick apples and farm stand sales. In the fall we harvest apples, which we pick, sort, press into cider, and either bottle for sale as sweet customers come to pick apples, buy sweet cider and donuts, and taste and buy hard cider. Once the apples

  9. 1. Open up Apple Mail. If you do not have a non Barnard email account already configured in Apple Mail you can skip to step 2. If you already have a different email

    E-Print Network [OSTI]

    1. Open up Apple Mail. If you do not have a non Barnard email account already configured in Apple. Then hit the "+ "symbol to add a new account. If you already have a Barnard account set up in Apple Mail will be set up in Apple Mail. 5. From within the Apple Mail program, click "Mail" at the top

  10. Specific heat of apple at different moisture contents and temperatures

    E-Print Network [OSTI]

    Viacheslav Mykhailyk; Nikolai Lebovka

    2013-05-11

    This work discusses results of experimental investigations of the specific heat, $C$, of apple in a wide interval of moisture contents ($W=0-0.9$) and temperatures ($T = 283-363$ K). The obtained data reveal the important role of the bound water in determination of $C(W,T)$ behaviour. The additive model for description of $C(W)$ dependence in the moisture range of $0.1apple was considered as a mixture of water and hydrated apple material (water plasticised apple) with specific heat $C_h$. The difference between $C_h$ and specific heat of dry apple, $\\Delta Cb=C_h-C_d$, was proposed as a measure of the excess contribution of bound water to the specific heat. The estimated amounts of bound water $W_b$ were comparable with the monolayer moisture content in apple. The analytical equation was proposed for approximation of $C(W,T)$ dependencies in the studied intervals of moisture content and temperature.

  11. Nonlinear Biochemical Signal Processing via Noise Propagation

    E-Print Network [OSTI]

    Kyung Hyuk Kim; Hong Qian; Herbert M. Sauro

    2013-09-10

    Single-cell studies often show significant phenotypic variability due to the stochastic nature of intra-cellular biochemical reactions. When the numbers of molecules, e.g., transcription factors and regulatory enzymes, are in low abundance, fluctuations in biochemical activities become significant and such "noise" can propagate through regulatory cascades in terms of biochemical reaction networks. Here we develop an intuitive, yet fully quantitative method for analyzing how noise affects cellular phenotypes based on identifying a system's nonlinearities and noise propagations. We observe that such noise can simultaneously enhance sensitivities in one behavioral region while reducing sensitivities in another. Employing this novel phenomenon we designed three biochemical signal processing modules: (a) A gene regulatory network that acts as a concentration detector with both enhanced amplitude and sensitivity. (b) A non-cooperative positive feedback system, with a graded dose-response in the deterministic case, that serves as a bistable switch due to noise-induced bimodality. (c) A noise-induced linear amplifier for gene regulation that requires no feedback. The methods developed in the present work allow one to understand and engineer nonlinear biochemical signal processors based on fluctuation-induced phenotypes.

  12. U-239: Apple iPhone SMS Processing Flaw Lets Remote Users Spoof...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    39: Apple iPhone SMS Processing Flaw Lets Remote Users Spoof SMS Source Addresses U-239: Apple iPhone SMS Processing Flaw Lets Remote Users Spoof SMS Source Addresses August 20,...

  13. Introduction This guide will assist you in connecting your Apple Mac to the University wireless networks.

    E-Print Network [OSTI]

    Balasuriya, Sanjeeva

    Introduction This guide will assist you in connecting your Apple Mac to the University wireless change your password. Procedure 1. Click the Apple Icon ( ) 2. Select `System Preferences' from the menu

  14. T-676: Apple iOS Certificate Chain Validation Flaw Lets Certain...

    Energy Savers [EERE]

    676: Apple iOS Certificate Chain Validation Flaw Lets Certain Remote Users Access or Modify SSLTLS Sessions T-676: Apple iOS Certificate Chain Validation Flaw Lets Certain Remote...

  15. U-121: Apple iOS Bugs Let Remote Users Execute Arbitrary Code...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    21: Apple iOS Bugs Let Remote Users Execute Arbitrary Code, Conduct Cross-Site Scripting Attacks, and Obtain Potentially Sensitive Information U-121: Apple iOS Bugs Let Remote...

  16. U-170: Apple QuickTime Multiple Flaws Let Remote Users Execute...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    0: Apple QuickTime Multiple Flaws Let Remote Users Execute Arbitrary Code U-170: Apple QuickTime Multiple Flaws Let Remote Users Execute Arbitrary Code May 16, 2012 - 7:00am...

  17. V-020: Apple QuickTime Multiple Flaws Let Remote Users Execute...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    0: Apple QuickTime Multiple Flaws Let Remote Users Execute Arbitrary Code V-020: Apple QuickTime Multiple Flaws Let Remote Users Execute Arbitrary Code November 9, 2012 - 6:00am...

  18. U-165: Apple iOS Bugs Let Remote Users Execute Arbitrary Code...

    Office of Environmental Management (EM)

    5: Apple iOS Bugs Let Remote Users Execute Arbitrary Code and Spoof Address Bar URLs U-165: Apple iOS Bugs Let Remote Users Execute Arbitrary Code and Spoof Address Bar URLs May 9,...

  19. V-171: Apple Safari Bugs Let Remote Users Execute Arbitrary Code...

    Broader source: Energy.gov (indexed) [DOE]

    Apple Safari Bugs Let Remote Users Execute Arbitrary Code and Conduct Cross-Site Scripting Attacks PLATFORM: Apple Safari prior to 6.0.5 ABSTRACT: Several vulnerabilities were...

  20. Introduction To configure Apple Mail to access your University student email account

    E-Print Network [OSTI]

    Balasuriya, Sanjeeva

    Introduction To configure Apple Mail to access your University student email account Procedure 1 8313 3000 or servicedesk@adelaide.edu.au Technology Services Configure Student Gmail - Apple Mail #12;

  1. Theor Appl Genet DOI 10.1007/s00122-007-0605-2

    E-Print Network [OSTI]

    Burke, John M.

    Theor Appl Genet DOI 10.1007/s00122-007-0605-2 123 ORIGINAL PAPER Universal markers for comparative Blvd, Boston, MA 02125, USA #12;Theor Appl Genet 123 genome sequence of Arabidopsis thaliana (e

  2. MSU Fruit Team Apple Maturity Report 2013 Northwest Region, Report Number 2

    E-Print Network [OSTI]

    MSU Fruit Team Apple Maturity Report 2013 Northwest Region, Report Number 2 September 11, 2013 will be testing apples for maturity for 2013, and results will be sent via fax and email to past apple maturity/centers/nwmihort/nwmihort_resources_and_reports#NWMIAppleMaturityReps Reports for other regions around the state can be viewed at http://msue.anr.msu.edu/resources/apple

  3. Apple and the Apple logo are trademarks of Apple Inc., registered in the U.S. and other countries. App Store is a service mark of Apple Inc. | Android and Google Play are trademarks of Google Inc. *The downloading and use of the myCigna Mobile App is subj

    E-Print Network [OSTI]

    . App Store is a service mark of Apple Inc. | Android and Google Play are trademarks of Google Inc. *The

  4. 2009 Biochemical Conversion Platform Review Report

    SciTech Connect (OSTI)

    Ferrell, John

    2009-12-01

    This document summarizes the recommendations and evaluations provided by an independent external panel of experts at the U.S. Department of Energy Biomass Program’s Biochemical Conversion platform review meeting, held on April 14-16, 2009, at the Sheraton Denver Downtown, Denver, Colorado.

  5. Kristin Ducrest Biochem 118-OSP Paris

    E-Print Network [OSTI]

    Brutlag, Doug

    Kristin Ducrest Biochem 118-OSP Paris Professor Doug Brutlag 11-15-02 Tackling Parkinson Disease with Bioinformatics and Genomics Parkinson disease (PD) is a neurodegenerative disease characterized most commonly to the genetics beneath the manifestation of the disease, the inheritance pattern of PD has been a subject

  6. Steve Jobs' creations simplified life, Apple enthusiasts say in mourning his death

    E-Print Network [OSTI]

    Fernandez, Eduardo

    Steve Jobs' creations simplified life, Apple enthusiasts say in mourning his death By ADAM PLAYFORD as soon as they got confirmation." Word of the Apple co-founder's death of pancreatic cancer hit hard live without a computer," said Joerg von Veltar, the founder of the Palm Beach Phoenix Apple User Group

  7. Configuring ICEMail for Apple Mail for MacOS 10.10 Yosemite

    E-Print Network [OSTI]

    Chen, Yiling

    Configuring ICEMail for Apple Mail for MacOS 10.10 Yosemite Once you have received notification on at https://icemail.harvard.edu, you will need to add the new settings in Apple Mail. Step 1. Launch Mail the Accounts tab. And click on the + in the lower left corner. (See Figure 2) Figure 2 SEAS-ICE Apple Mail

  8. WHOLE-FARM APPLE ARTHROPOD MANAGEMENT USING REDUCED-RISK TACTICS AND IPM SAMPLING AND MONITORING

    E-Print Network [OSTI]

    Agnello, Arthur M.

    WHOLE-FARM APPLE ARTHROPOD MANAGEMENT USING REDUCED-RISK TACTICS AND IPM SAMPLING AND MONITORING management programs in apples, using provisional action thresholds for specific major pests based on previous-farm approaches for managing the arthropod pests of apple orchards that rely on RR and OP-replacement insecticides

  9. 130 Florida Entomologist 93(1) March 2010 BIOLOGICAL CONTROL OF TROPICAL SODA APPLE

    E-Print Network [OSTI]

    Ma, Lena

    130 Florida Entomologist 93(1) March 2010 BIOLOGICAL CONTROL OF TROPICAL SODA APPLE (SOLANACEAE for natural ene- mies of the invasive plant tropical soda apple, Solanum viarum Dunal (Solanaceae) were con apple in Brazil and Paraguay (Medal et al. 1996). A biological control program was initiated

  10. Light brown apple moth (LBAM) (Epiphyas postvittana) is an important invasive leafroller pest

    E-Print Network [OSTI]

    Ishida, Yuko

    Light brown apple moth (LBAM) (Epiphyas postvittana) is an important invasive leafroller pest for Light Brown Apple Moth IN CALIFORNIA NURSERIES Eggs are not easily observed by nursery scouts or other the head. Male light brown apple moths caught in pheromone traps. e wing-color pattern of males can

  11. Minimal Spray Strategy for Frosted Apple Trees Nikki Rothwell, District Fruit IPM Educator

    E-Print Network [OSTI]

    1 Minimal Spray Strategy for Frosted Apple Trees Nikki Rothwell, District Fruit IPM Educator Amy morning frost of Saturday, May 6th , many apples in the northwest region were affected. Based on some preliminary observations, we have found most apples in 'cherry sites' fared pretty well, although some trees

  12. Title: Use of Physical Barriers to Prevent Borer Infestation of Apple Burrknots Project Leaders

    E-Print Network [OSTI]

    Agnello, Arthur M.

    Title: Use of Physical Barriers to Prevent Borer Infestation of Apple Burrknots Project Leaders of burrknot tissue on apple dwarfing rootstocks is an increasing problem throughout the northeast. One into the winter. We also discuss economic considerations. Background and Justification: Apple growers

  13. THE APPLE GAME AND THE PRESSING-DOWN LEMMA Brian White

    E-Print Network [OSTI]

    White, Brian

    THE APPLE GAME AND THE PRESSING-DOWN LEMMA Brian White Math 161 Lecture Notes (Winter 2005) Recall, but for every apple game is played in a series of stages, one for each element of 1. At stage 0, you are given a countable collection of apples. At each stage n 1 with n > 0: (1) If you have

  14. MSU Fruit Team Apple Maturity Report 2014 Northwest Region, Report Number 3

    E-Print Network [OSTI]

    MSU Fruit Team Apple Maturity Report 2014 Northwest Region, Report Number 3: September 24, 2014 Nikki Rothwell and Emily Pochubay, Extension Fruit Educators Apples are maturing slowly, but warm and sunny weather should move fruit along this week. We expect apples to be ready for harvest close

  15. Low and High-Level Visual Feature Based Apple Detection from Multi-modal Images

    E-Print Network [OSTI]

    Wachs, Juan

    1 Low and High-Level Visual Feature Based Apple Detection from Multi-modal Images J. P. Wachs1 , H discusses the development of a machine vision system, capable of recognizing occluded green apples within a tree canopy. This involves the detection of "green" apples within scenes of "green leaves", shadow

  16. http://agbioresearch.msu.edu/centers/nwmihort/ MSU Fruit Team Apple Maturity Report 2014

    E-Print Network [OSTI]

    http://agbioresearch.msu.edu/centers/nwmihort/ MSU Fruit Team Apple Maturity Report 2014 Northwest Gingergold harvest continues, and many growers are waiting on McIntosh harvest to begin. Apples are coloring nicely with the cool temperatures. Cool temperatures have hit the northwest region, and apple maturity

  17. Light brown apple moth Epiphyas postvittana Michigan State University's invasive species factsheets

    E-Print Network [OSTI]

    Isaacs, Rufus

    Light brown apple moth Epiphyas postvittana Michigan State University's invasive species factsheets University IPM Program and M. Philip of Michigan Department of Agriculture. The light brown apple moth and agricultural commodities. Michigan risk maps for exotic plant pests. Other common names apple leafroller

  18. MSU Fruit Team Apple Maturity Report 2013 Northwest Region, Report Number 5: October 2, 2013

    E-Print Network [OSTI]

    MSU Fruit Team Apple Maturity Report 2013 Northwest Region, Report Number 5: October 2, 2013 Nikki Rothwell and Emily Pochubay, Extension Fruit Educators This is the fifth week of 2013 apple maturity testing at NWMHRC. Results will be sent via fax and email to past apple maturity list subscribers. Results

  19. MSU Fruit Team Apple Maturity Report 2013 Northwest Region, Report Number 7: October 16, 2013

    E-Print Network [OSTI]

    MSU Fruit Team Apple Maturity Report 2013 Northwest Region, Report Number 7: October 16, 2013 Nikki Rothwell and Emily Pochubay, Extension Fruit Educators This is the seventh week of 2013 apple maturity testing at NWMHRC. Results will be sent via fax and email to past apple maturity list subscribers. Results

  20. MSU Fruit Team Apple Maturity Report 2013 Northwest Region, Report Number 1

    E-Print Network [OSTI]

    MSU Fruit Team Apple Maturity Report 2013 Northwest Region, Report Number 1 September 4, 2013 General Comments - The NWMHRC will be testing apples for maturity for 2013, and results will be sent via fax and email to past apple maturity list subscribers. Results will also be available at: http

  1. MSU Fruit Team Apple Maturity Report 2014 Northwest Region, Report Number 6: October 15, 2014

    E-Print Network [OSTI]

    MSU Fruit Team Apple Maturity Report 2014 Northwest Region, Report Number 6: October 15, 2014 Emily, which is slowing apple harvest in the north. Cool weather and rain continues across northwest Michigan at the NWMHRC, many growers dropped off samples for testing because apple varieties have been slow to mature

  2. Apple Tree, NH Big Tree for May By Anne Krantz, NH Big Tree Team,

    E-Print Network [OSTI]

    New Hampshire, University of

    Apple Tree, NH Big Tree for May By Anne Krantz, NH Big Tree Team, UNH Cooperative Extension The explosion of apple blossoms in May transforms the most gnarled old tree into a delicate cloud of beauty (1817-1862) in his essay "The Wild Apple Tree," described the blossoms perfectly: `The flowers

  3. MSU Fruit Team Apple Maturity Report 2013 Northwest Region, Report Number 6: October 9, 2013

    E-Print Network [OSTI]

    MSU Fruit Team Apple Maturity Report 2013 Northwest Region, Report Number 6: October 9, 2013 Nikki Rothwell and Emily Pochubay, Extension Fruit Educators This is the sixth week of 2013 apple maturity testing at NWMHRC. Results will be sent via fax and email to past apple maturity list subscribers. Results

  4. Apple detection in natural tree canopies from multimodal images J. P. Wachs1,2

    E-Print Network [OSTI]

    Wachs, Juan

    1 Apple detection in natural tree canopies from multimodal images J. P. Wachs1,2 , H. I. Stern2 , T apples within a tree canopy using infra-red and color images in order to achieve automated harvesting. Infra-red provides clues regarding the physical structure and location of the apples based

  5. MSU Fruit Team Apple Maturity Report 2013 Northwest Region, Report Number 3

    E-Print Network [OSTI]

    MSU Fruit Team Apple Maturity Report 2013 Northwest Region, Report Number 3 September 18, 2013 Nikki Rothwell and Emily Pochubay, Extension Fruit Educators This is the third week of 2013 apple maturity testing at NWMHRC. General Comments - The NWMHRC will be testing apples for maturity for 2013

  6. APPL: A Probability Programming Language Maj. Andrew G. GLEN, Diane L. EVANS, and Lawrence M. LEEMIS

    E-Print Network [OSTI]

    Leemis, Larry

    APPL: A Probability Programming Language Maj. Andrew G. GLEN, Diane L. EVANS, and Lawrence M having arbitrary distributions. This arti- cle presents a prototype probability package named APPL (A probability software package, referred to as "A Prob- ability Programming Language" (APPL), that fills

  7. Enhanced the expression of an apple gene that switches on a tree's natural defenses

    E-Print Network [OSTI]

    · Enhanced the expression of an apple gene that switches on a tree's natural defenses when fire the roots and killing the tree. Fire blight can kill an apple tree in as little as 30 days. It's called fire Sundin/MSU George Sundin/MSU #12;Enhanced the expression of an apple gene that switches on a tree

  8. Borer problems and their control in dwarf apple trees David Kain, Entomology, NYSAES, Geneva, NY

    E-Print Network [OSTI]

    Agnello, Arthur M.

    Borer problems and their control in dwarf apple trees David Kain, Entomology, NYSAES, Geneva, NY in western New York, were invading burrknots on dwarf apple trees. About the same time, Dick Straub seemed to be becoming more common in dwarf apple plantings, as well. Based on Deb's alert, we decided

  9. MSU Fruit Team Apple Maturity Report 2013 Northwest Region, Report Number 4: September 25, 2013

    E-Print Network [OSTI]

    MSU Fruit Team Apple Maturity Report 2013 Northwest Region, Report Number 4: September 25, 2013 Nikki Rothwell and Emily Pochubay, Extension Fruit Educators This is the fourth week of 2013 apple maturity testing at NWMHRC. Results will be sent via fax and email to past apple maturity list subscribers

  10. Li2O Particulate Flow Concept, APPLE APEX Interim Report November, 1999

    E-Print Network [OSTI]

    California at Los Angeles, University of

    Li2O Particulate Flow Concept, APPLE APEX Interim Report November, 1999 9-1 CHAPTER 9: Li2O PARTICULATE FLOW CONCEPT ­ APPLE DESIGN Contributors Lead Author: Dai Kai Sze Dai Kai Sze, Zhanhe Wang (ANL Particulate Flow Concept, APPLE APEX Interim Report November, 1999 9-2 9. LI2O PARTICULATE FLOW CONCEPT

  11. Apple Price List Buy your Mac with us and qualify for free warranty service

    E-Print Network [OSTI]

    Apple Price List Buy your Mac with us and qualify for free warranty service on campus storage to 256GB storage $200.00 Apple USB SuperDrive $79.00 Canon Printer with cables & paper $74://computerstore.unh.edu/support for more details on warranty coverage, loaner policies, and more. #12;Apple Price List Buy your Mac with us

  12. Privacy Failures in Encrypted Messaging Services: Apple iMessage and Beyond

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    Privacy Failures in Encrypted Messaging Services: Apple iMessage and Beyond Scott E. Coull Red of communication among consumers around the world. Apple iMessage, for example, handles over 2 bil- lion message evaluation focuses on Apple iMessage, the attacks are completely generic and we show how they can be applied

  13. New SRC APPLE ll Variable Polarization Beamline

    SciTech Connect (OSTI)

    M Severson; M Bissen; M Fisher; G Rogers; R Reininger; M Green; D Eisert; B Tredinnick

    2011-12-31

    SRC has recently commissioned a new Varied Line-Spacing Plane Grating Monochromator (VLS-PGM) utilizing as its source a 1 m long APPLE II insertion device in short-straight-section 9 of the Aladdin storage ring. The insertion device reliably delivers horizontal, vertical, and right and left circularly polarized light to the beamline. Measurements from an in situ polarimeter can be used for undulator corrections to compensate for depolarizing effects of the beamline. The beamline has only three optical elements and covers the energy range from 11.1 to 270 eV using two varied line-spacing gratings. A plane mirror rotates to illuminate the gratings at the correct angle to cancel the defocus term at all photon energies. An exit slit and elliptical-toroid refocusing mirror complete the beamline. Using a 50 {mu}m exit slit, the beamline provides moderate to high resolution, with measured flux in the mid 10{sup 12} (photons/s/200 mA) range, and a spot size of 400 {mu}m horizontal by 30 {mu}m vertical.

  14. Using the Apple LaserWriter at ANL

    SciTech Connect (OSTI)

    Errion, S.M.; Thommes, M.M. Caruthers, C.M.

    1987-09-01

    Using the Apple LaserWriter at ANL (ANL/TM 452) explains how Argonne computer users (with CMS, MVS, or VAX/VMS accounts) can print quality text and graphics on the Apple LaserWriter. Currently, applications at Argonne that are compatible with the Apple LaserWriter include Waterloo Script, CA/ISSCO graphics software (i.e., Cuechart, Tellagraf, and Disspla), SAS/Graph, ANSYS (version 4.2), and some personal computer test and graphics software. This manual does not attempt to cover use of the Apple LaserWriter with other applications, though some information on the handling of PostScript-compatible files may be valid for other applications. Refer to the documentation of those applications to learn how they work with the Apple LaserWriter. Most of the information in this manual applies to the Allied Linotype L300P typesetter in Building 222. However, the typesetter is not a high volume output device and should be used primarily for high quality (1250 and 2500 dots per inch) final copy output for Laboratory publications prior to making printing plates. You should print all drafts and proof pages on LaserWriers or other printers compatible with the PostScript page description language. Consult with Graphic Arts (at extension 2-5603) to determine the availability of the typesetter for printing the final copy of your document or graphics application. Since the Apple LaserWriter itself produces good quality output (300 dots per inch), we expect that most internal documents consisting of test or graphics will continue to be printed at LaserWriters distributed throughout the Laboratory. 5 figs., 2 tabs.

  15. Firm develops own EMS built on Apple computer

    SciTech Connect (OSTI)

    Pospisil, R.

    1982-04-05

    Firestone Fibers and Textile Co. programmed a $2000 desktop Apple II computer and special electronic panels designed by the engineering staff to perform process control and other energy-management functions. The system should reduce natural gas consumption 40% and save the company up to $75,000 a year by reducing the amount of hot air exhausted from fabric-treating ovens. The system can be expanded to control lights and space-conditioning equipment. The company is willing to negotiate with other firms to market the panels. The Apple II was chosen because it has a high capacity for data acquisition and testing and because of the available software. (DCK)

  16. Characterization of the Carbohydrate Binding Module 18 gene family in the amphibian pathogen Batrachochytrium dendrobatidis.

    E-Print Network [OSTI]

    Liu, Peng; Stajich, Jason E

    2015-01-01

    a! chitin9binding! module. ! Appl! Microbiol! Biotechnol. !Species9specific! chitin9binding! module! 18! expansion! in!of the Carbohydrate Binding Module 18 gene family in the

  17. Limits to the potential distribution of light brown apple moth in Arizona–California based on climate suitability and host plant availability

    E-Print Network [OSTI]

    Gutierrez, Andrew Paul; Mills, Nicholas J.; Ponti, Luigi

    2010-01-01

    503–531 Dumbleton LJ (1932) The apple leaf roller (TortrixJW (1937) The light-brown apple moth (Tortrix post- vittana,distribution of light brown apple moth in Arizona–California

  18. Reliable estimation of biochemical parameters from C3 leafphotosynthe...

    Office of Scientific and Technical Information (OSTI)

    Reliable estimation of biochemical parameters from C3 leaf photosynthesis-intercellular carbon dioxide response curves Citation Details In-Document Search Title: Reliable...

  19. Modeling Tomorrow's Biorefinery--the NREL Biochemical Pilot Plant

    SciTech Connect (OSTI)

    Not Available

    2008-03-01

    Brochure describing the capabilities of NREL's Biochemical Pilot Plant. In this facility, researchers test ideas for creating high-value products from cellulosic biomass.

  20. Biochemical Production of Ethanol from Corn Stover: 2007 State...

    Broader source: Energy.gov (indexed) [DOE]

    Process Design and Economics for Biochemical Conversion of Lignocellulosic Biomass to Ethanol: Dilute-Acid Pretreatment and Enzymatic Hydrolysis of Corn Stover Process Design and...

  1. Design and Optimization of a Biochemical Production Platform...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Review Eric J. Steen, Ph.D. Lygos, Inc. DESIGN & OPTIMIZATION OF A BIOCHEMICAL PRODUCTION PLATFORM WITH BIOSENSOR-GUIDED SYNTHETIC EVOLUTION 2 CELLULOSIC SUGARS MALONYL-COA...

  2. U-222: Apple Safari Bugs Let Remote Users Execute Arbitrary Code...

    Broader source: Energy.gov (indexed) [DOE]

    Apple Safari Bugs Let Remote Users Execute Arbitrary Code, Spoof the URL Address Bar, Conduct Cross-Site Scripting Attacks, and Obtain Potentially Sensitive Information PLATFORM:...

  3. PROGRESS IN PHOTOVOLTAICS: RESEARCH AND APPLICATIONS Prog. Photovolt: Res. Appl. 2006; 14:603614

    E-Print Network [OSTI]

    PROGRESS IN PHOTOVOLTAICS: RESEARCH AND APPLICATIONS Prog. Photovolt: Res. Appl. 2006; 14 Reactive Ion Etching of Dielectrics and Silicon for Photovoltaic Applications Prakash N. K. Deenapanray1

  4. Use of an Apple IIe microcomputer for pyrolysis data acquisition

    SciTech Connect (OSTI)

    Not Available

    1988-02-01

    An Apple IIe microcomputer is being used to collect data and to control a pyrolysis system. Pyrolysis data for bitumen and kerogen are widely used to estimate source rock maturity. For a detailed analysis of kinetic parameters, however, data must be obtained more precisely than for routine pyrolysis. The authors discuss the program which controls the temperature ramp of the furnace that heats the sample, and collects data from a thermocouple in the furnace and from the flame ionization detector measuring evolved hydrocarbons. These data are stored on disk for later use by programs that display the results of the experiment or calculate kinetic parameters. The program is written in Applesoft BASIC with subroutines in Apple assembler for speed and efficiency.

  5. Mercury residues in south Florida apple snails (Pomacea paludosa)

    SciTech Connect (OSTI)

    Eisemann, J.D.; Beyer, W.N.; Morton, A.; Bennetts, R.E.

    1997-05-01

    Mercury concentrations in the sediments of south Florida wetlands have increased three fold in the last century. Because south Florida is home to many endemic and endangered species, it is important to understand the potential impacts of mercury in this ecosystem`s food web. Recent research by Malley et al. has shown mollusks to be sensitive indicators of methyl mercury which can reflect small differences in background methyl mercury concentrations. In this study, we attempted to determine if the apple snail (Pomacea paludosa) or its eggs are good indicators of bioavailable mercury. Then, using the apple snail as an indicator, we attempted to determine geographic differences in the concentrations of mercury in south Florida. 12 refs., 1 fig., 1 tab.

  6. Theor Appl Genet (2008) 116:455463 DOI 10.1007/s00122-007-0682-2

    E-Print Network [OSTI]

    Parrott, Wayne

    2008-01-01

    Theor Appl Genet (2008) 116:455­463 DOI 10.1007/s00122-007-0682-2 123 ORIGINAL PAPER EVects, USA #12;456 Theor Appl Genet (2008) 116:455­463 123 molecular markers and the discovery

  7. March 11, 2015 ITCS QUICK REFERENCE GUIDE: CONNECT TO VCL -APPLE Page 1 2015 ITCS East Carolina University

    E-Print Network [OSTI]

    Gopalakrishnan, K.

    March 11, 2015 ITCS QUICK REFERENCE GUIDE: CONNECT TO VCL - APPLE Page 1 © 2015 ITCS East Carolina University Connect to VCL - Apple The first time you log in, install the Citrix Receiver client (once only QUICK REFERENCE GUIDE: CONNECT TO VCL - APPLE Page 2 © 2015 ITCS East Carolina University Click Continue

  8. Four species of Zygophiala (Schizothyriaceae, Capnodiales) are associated with the sooty blotch and flyspeck complex on apple

    E-Print Network [OSTI]

    Harrington, Thomas C.

    and flyspeck complex on apple Jean Carlson Batzer Maria Mercedes Diaz Arias Thomas C. Harrington Mark L: Sooty blotch and flyspeck (SBFS) is a complex of fungi that cause late-season blemishes of apple anamorph Zygophiala jamaicensis), caused flyspeck on apple. In the present study we compared morphology

  9. A New Canker Disease of Apple, Pear, and Plum Rootstocks Caused by Diaporthe ambigua in South Africa

    E-Print Network [OSTI]

    A New Canker Disease of Apple, Pear, and Plum Rootstocks Caused by Diaporthe ambigua in South., Wingfield. B. D.. Wingfield. M. 1., and Calitz. F. J. 1996. A new canker disease of apple. pear, and plum was found to be the c:J.useof a newly recognized disease of apple. pear, and plum rootstocks in South Africa

  10. March 5, 2015 ITCS QUICK REFERENCE GUIDE: CONFIGURE AIRWATCH FOR APPLE Page 1 2015 ITCS East Carolina University

    E-Print Network [OSTI]

    Gopalakrishnan, K.

    March 5, 2015 ITCS QUICK REFERENCE GUIDE: CONFIGURE AIRWATCH FOR APPLE Page 1 © 2015 ITCS East getting started, have ready: 1. Apple ID for access to the App Store 2. PirateID/passphrase 3 GUIDE: CONFIGURE AIRWATCH FOR APPLE Page 2 © 2015 ITCS East Carolina University Step 6. You should now

  11. J. Math. Anal. Appl. 423 (2015) 14691479 Contents lists available at ScienceDirect

    E-Print Network [OSTI]

    Poggiale, Jean-Christophe

    2015-01-01

    J. Math. Anal. Appl. 423 (2015) 1469­1479 Contents lists available at ScienceDirect Journal al. / J. Math. Anal. Appl. 423 (2015) 1469­1479 where stands for the derivative d/dt, and f, g C1 (R

  12. T-634: Apple Mac OS X MacDefender Fake Antivirus Malicious Software

    Broader source: Energy.gov [DOE]

    Apple Mac OS X users could infect their systems after visiting a malicious web page. Reports suggest that the Apple Safari web browser could allow automatic download and execution of the JavaScript-based malware because of an incorrectly set security option in Safari.

  13. Journal Review: Biomolecular Engineering, Bioengineering, Biochemicals, and Food Directed Evolution: Past, Present, and Future

    E-Print Network [OSTI]

    Zhao, Huimin

    Journal Review: Biomolecular Engineering, Bioengineering, Biochemicals, and Food Directed Evolution of Chemical Engineers AIChE J, 59: 1432­1440, 2013 Keywords: biochemical engineering, bioengineering

  14. 510 Plant Disease / Vol. 97 No. 4 Etiology of Moldy Core, Core Browning, and Core Rot of Fuji Apple in China

    E-Print Network [OSTI]

    Biggs, Alan R.

    510 Plant Disease / Vol. 97 No. 4 Etiology of Moldy Core, Core Browning, and Core Rot of Fuji Apple, and core rot of Fuji apple in China. Plant Dis. 97:510-516. `Fuji' apple fruit were collected in Shaanxi to species. Pathogenicity was determined by cutting apple fruit into halves and daubing spore suspensions

  15. Multiple capillary biochemical analyzer with barrier member

    DOE Patents [OSTI]

    Dovichi, Norman J. (Edmonton, CA); Zhang, Jian Z. (Edmonton, CA)

    1996-01-01

    A multiple capillary biochemical analyzer for sequencing DNA and performing other analyses, in which a set of capillaries extends from wells in a microtiter plate into a cuvette. In the cuvette the capillaries are held on fixed closely spaced centers by passing through a sandwich construction having a pair of metal shims which squeeze between them a rubber gasket, forming a leak proof seal for an interior chamber in which the capillary ends are positioned. Sheath fluid enters the chamber and entrains filament sample streams from the capillaries. The filament sample streams, and sheath fluid, flow through aligned holes in a barrier member spaced close to the capillary ends, into a collection chamber having a lower glass window. The filament streams are illuminated above the barrier member by a laser, causing them to fluoresce. The fluorescence is viewed end-on by a CCD camera chip located below the glass window. The arrangement ensures an equal optical path length from all fluorescing spots to the CCD chip and also blocks scattered fluorescence illumination, providing more uniform results and an improved signal to noise ratio.

  16. Multiple capillary biochemical analyzer with barrier member

    DOE Patents [OSTI]

    Dovichi, N.J.; Zhang, J.Z.

    1996-10-22

    A multiple capillary biochemical analyzer is disclosed for sequencing DNA and performing other analyses, in which a set of capillaries extends from wells in a microtiter plate into a cuvette. In the cuvette the capillaries are held on fixed closely spaced centers by passing through a sandwich construction having a pair of metal shims which squeeze between them a rubber gasket, forming a leak proof seal for an interior chamber in which the capillary ends are positioned. Sheath fluid enters the chamber and entrains filament sample streams from the capillaries. The filament sample streams, and sheath fluid, flow through aligned holes in a barrier member spaced close to the capillary ends, into a collection chamber having a lower glass window. The filament streams are illuminated above the barrier member by a laser, causing them to fluoresce. The fluorescence is viewed end-on by a CCD camera chip located below the glass window. The arrangement ensures an equal optical path length from all fluorescing spots to the CCD chip and also blocks scattered fluorescence illumination, providing more uniform results and an improved signal-to-noise ratio. 12 figs.

  17. Preparing the BESSY APPLE Undulators for Top-Up Operation

    SciTech Connect (OSTI)

    Bahrdt, J.; Frentrup, W.; Gaupp, A.; Scheer, M.

    2007-01-19

    BESSY plans to go to topping up operation in the near future. A high injection efficiency is essential to avoid particle losses inside the undulator magnets and to ensure a low radiation background in the beamlines. Dynamic and static multipoles of the insertion devices have to be minimized to accomplish this requirement. APPLE II devices show strong dynamic multipoles in the elliptical and vertical polarization mode. Measurements before and after shimming of these multipoles are presented. The static multipoles of the BESSY UE56-2 which are due to systematic block inhomgeneities have successfully been shimmed recovering the full dynamic aperture.

  18. Apple Valley, California: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION J APPENDIX E LISTStar Energy LLC Jump to: navigation,Summaries | Open EnergyRoadmap andApiWestApple

  19. Property:Incentive/ApplDsc | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION J APPENDIX ECoop Inc Jump to:Newberg,Energy LLCALLETE Inc d bGeothermalAreaApplDsc Jump to:

  20. 2011 Biomass Program Platform Peer Review: Biochemical Conversion

    SciTech Connect (OSTI)

    Pezzullo, Leslie

    2012-02-01

    This document summarizes the recommendations and evaluations provided by an independent external panel of experts at the 2011 U.S. Department of Energy Biomass Program’s Biochemical Conversion Platform Review meeting.

  1. Solid state fermentation system for production of ethanol from apple pomace

    SciTech Connect (OSTI)

    Hang, Y.D.; Lee, C.Y.; Woodams, E.E.

    1982-01-01

    A solid state fermentation system for the production of ethanol from apple pomace with a Montrachet strain of Saccharomyces cerevisiae is described. The yields of ethanol varied from about 29 g to more than 40 g/kg of apple pomace, depending on the samples fermented. Separation of up to 99% of the ethanol from spent qpple pomace was achieved with a rotary vacuum evaporator. Alcohol fermentation of apple pomace might be an efficient method of alleviating waste disposal problems with the concomitant production of ethanol.

  2. Interactions of Lignin and Hemicellulose and Effects on Biomass Deconstruction

    E-Print Network [OSTI]

    Li, Hongjia

    2012-01-01

    the way. Appl Biochem Biotech. 2001 Spr;91-3:5-21. Wyman CE.hydrolysis. Appl Biochem Biotech. 2006 Mar;130(1-3):427-35.aurantiacus. Appl Biochem Biotech. 2010 Oct;162(4):1195-205.

  3. Tracking Hemicellulose and Lignin Deconstruction During Hydrothermal Pretreatment of Biomass

    E-Print Network [OSTI]

    McKenzie, Heather Lorelei

    2012-01-01

    parameter. Appl. Biochem. Biotech. 1990; 24/25: 1-14. WymanASPEN-Plus®. Appl. Biochem. Biotech. 2004; 115: 1087-1102. (hydrolysis. Appl. Biochem. Biotech. 2001; 92: 377-386.

  4. The Macolumn: Desperately seeking software. [Geologic software for the Apple Macintosh

    SciTech Connect (OSTI)

    Busbey, A.B.

    1988-08-01

    The Apple Macintosh has been available since 1984, but there has been little development of commercial geological software for it. The author briefly reviews what geological software is available for the Macintosh

  5. Theor Appl Genet DOI 10.1007/s00122-009-1119-x

    E-Print Network [OSTI]

    Klee, Harry J.

    and is suppressed by exposure to exogenous ethyl- ene. Upon maturation, fruits enter the autocatalytic system 2 #12;Theor Appl Genet 123 Yang 1987). Much of our knowledge about ethylene action comes from genetic

  6. NUMERICAL LINEAR ALGEBRA WITH APPLICATIONS Numer. Linear Algebra Appl. 2011; 18:961980

    E-Print Network [OSTI]

    De Sterck, Hans

    NUMERICAL LINEAR ALGEBRA WITH APPLICATIONS Numer. Linear Algebra Appl. 2011; 18:961­980 Published aggregation method of [1], and the Markov chain algebraic multigrid (MCAMG) method of [3] using the OTF

  7. Ann. appl. Bid. (1 998), 133:17-30 Printed in Grerrr Britain 17

    E-Print Network [OSTI]

    Ann. appl. Bid. (1 998), 133:17-30 Printed in Grerrr Britain 17 Chemical control of Alternaria to an ineffective chemical spray programme (Swart, unpublished data). These trees took two seasons to recover

  8. Mitochondrial and Ion Channel Gene Alterations in Autism

    E-Print Network [OSTI]

    2012-01-01

    deficient endophenotype in autism. Am J Biochem Biotechnol.4:198–207. 10. Lombard J. Autism: a mitochondrial disorder?abnormalities in infantile autism. J Child Neurol. 1996; 11:

  9. A Fixed Gap APPLE II Undulator for SLS

    SciTech Connect (OSTI)

    Schmidt, T.; Imhof, A.; Ingold, G.; Jakob, B.; Vollenweider, C.

    2007-01-19

    To vary the polarization vector of an APPLE II undulator continuously from 0 - 180 deg., all four magnet arrays need to be movable. Following the adjustable-phase undulator approach by R. Carr, a 3.4 m long fixed gap undulator for SLS with a gap of 11.6 mm has been constructed. It will be installed in fall 2006. The gap drive is replaced by a pair-wise shift of the magnet arrays to change the energy, while the polarization is changed by shifts of diagonal arrays. The high injection efficiency and standard operation top-up mode at the SLS allows this simplified undulator design. The design as well as the operational aspects will be discussed.

  10. Fermion Generations from "Apple-Shaped" Extra Dimensions

    E-Print Network [OSTI]

    Merab Gogberashvili; Pavle Midodashvili; Douglas Singleton

    2007-08-13

    We examine the behavior of fermions in the presence of an internal compact 2-manifold which in one of the spherical angles exhibits a conical character with an obtuse angle. The extra manifold can be pictured as an apple-like surface i.e. a sphere with an extra "wedge" insert. Such a surface has conical singularities at north and south poles. It is shown that for this setup one can obtain, in four dimensions, three trapped massless fermion modes which differ from each other by having different values of angular momentum with respect to the internal 2-manifold. The extra angular momentum acts as the family label and these three massless modes are interpreted as the three generations of fundamental fermions.

  11. A possibility for using an APPLE undulator to generate a photon beam with transverse optical modes.

    SciTech Connect (OSTI)

    Sasaki, S.; McNulty, I.; Shimada, T.; JAEA

    2008-01-01

    We investigate use of an APPLE-type undulator for generating Laguerre-Gaussian (LG) and Hermite-Gaussian (HG) mode beams. We find that the second harmonic radiation in the circular mode corresponds to an LG beam with l=1, and the second harmonic in the linear mode corresponds to an HG beam with l=1. The combination of an APPLE undulator and conventional monochromator optics may provide an opportunity for a new type of experimental research in the synchrotron radiation community.

  12. The Effects of Surfactant Pretreatment and Xylooligomers on Enzymatic Hydrolysis of Cellulose and Pretreated Biomass

    E-Print Network [OSTI]

    Qing, Qing

    2010-01-01

    Technical and economic evaluation. Applied Biochemistry andprocess. Technical and economic evaluation. Appl. Biochem.process. Technical and economic evaluation. Appl. Biochem.

  13. Biochemical Production of Endophytic Yeast Biofuel: what and why

    E-Print Network [OSTI]

    Brown, Sally

    , local production of crops, CO2 reincorporation Degrade lands due to oil sand mining, drilling, exBiochemical Production of Endophytic Yeast Biofuel: what and why In the U.S., the debate about because the farms are growing corns (first generation) for fuel production instead of for human and animal

  14. A modular microfluidic architecture for integrated biochemical analysis

    E-Print Network [OSTI]

    Barron, Annelise E.

    A modular microfluidic architecture for integrated biochemical analysis Kashan A. Shaikh*, Kee Suk for review November 15, 2004) Microfluidic laboratory-on-a-chip (LOC) systems based on a mod- ular (lead) at a sensitivity of 500 nM in microfluidic breadboard

  15. Mutual information in time-varying biochemical systems

    E-Print Network [OSTI]

    Filipe Tostevin; Pieter Rein ten Wolde

    2010-06-16

    Cells must continuously sense and respond to time-varying environmental stimuli. These signals are transmitted and processed by biochemical signalling networks. However, the biochemical reactions making up these networks are intrinsically noisy, which limits the reliability of intracellular signalling. Here we use information theory to characterise the reliability of transmission of time-varying signals through elementary biochemical reactions in the presence of noise. We calculate the mutual information for both instantaneous measurements and trajectories of biochemical systems for a Gaussian model. Our results indicate that the same network can have radically different characteristics for the transmission of instantaneous signals and trajectories. For trajectories, the ability of a network to respond to changes in the input signal is determined by the timing of reaction events, and is independent of the correlation time of the output of the network. We also study how reliably signals on different time-scales can be transmitted by considering the frequency-dependent coherence and gain-to-noise ratio. We find that a detector that does not consume the ligand molecule upon detection can more reliably transmit slowly varying signals, while an absorbing detector can more reliably transmit rapidly varying signals. Furthermore, we find that while one reaction may more reliably transmit information than another when considered in isolation, when placed within a signalling cascade the relative performance of the two reactions can be reversed. This means that optimising signal transmission at a single level of a signalling cascade can reduce signalling performance for the cascade as a whole.

  16. Multiplicative colored noise in linearized models of biochemical reaction networks

    E-Print Network [OSTI]

    Ingalls, Brian

    Multiplicative colored noise in linearized models of biochemical reaction networks Matthew Scott is often modeled by white noise, though results obtained in this fashion tend to overstate the effect to a model of bacterial chemotaxis with multiple explicit noise sources. The frequency response

  17. Author's personal copy Molecular & Biochemical Parasitology 155 (2007) 167171

    E-Print Network [OSTI]

    Davis, Richard E.

    2007-01-01

    Author's personal copy Molecular & Biochemical Parasitology 155 (2007) 167­171 Short technical report An improved and secreted luciferase reporter for schistosomes Guofeng Cheng, Richard E. Davis in schistosomes. In the current study, we demonstrate that a Gaussia luciferase reporter leads to significantly

  18. Characterization and application of vortex flow adsorption for simplification of biochemical product downstream processing

    E-Print Network [OSTI]

    Ma, Junfen, 1972-

    2003-01-01

    One strategy to reduce costs in manufacturing a biochemical product is simplification of downstream processing. Biochemical product recovery often starts from fermentation broth or cell culture. In conventional downstream ...

  19. Engineering model reduction of bio-chemical kinetic David Csercsik, Katalin M. Hangos

    E-Print Network [OSTI]

    Gorban, Alexander N.

    Engineering model reduction of bio-chemical kinetic models D´avid Csercsik, Katalin M. Hangos, Hungary Significance and Aim Bio-chemical kinetic models of enzyme kinetic processes, as well reaction kinetic scheme. Therefore it is of great importance to develop bio-chemically meaningful

  20. Effects of acid rain on apple tree productivity and fruit quality

    SciTech Connect (OSTI)

    Forsline, P.L.; Musselman, R.C.; Kender, W.J.; Dee, R.J.

    1983-01-01

    Mature 'McIntosh', 'Empire', and 'Golden Delicious' apple trees (Malus domestica Borkh.) were sprayed with simulated acid rain solutions in the pH range of 2.5 to 5.5 at full bloom in 1980 and in 1981. In 1981, weekly sprays were applied at pH 2.75 and pH 3.25. Necrotic lesions developed on apple petals at pH 2.5 with slight injury appearing at pH 3.0 and pH 3.5. Apple foliage had no acid rain lesions at any of the pH levels tested. Pollen germination was reduced at ph 2.5 in 'Empire'. Slight fruit set reduction at pH 2.5 was observed in 'McIntosh'. The incidence of russetting on 'Golden Delicious' fruits was ameliorated by the presence of rain-exclusion chambers but was not affected by acid rain. With season-long sprays at pH 2.75, there was a slight delay in maturity and lower weight of 'McIntosh' apples. Even at the lowest pH levels no detrimental effects of simulated acid rain were found on apple tree productivity and fruit quality when measured as fruit set, seed number per fruit, and fruit size and appearance.

  1. You can use Apple mobile device to access your Exchange account. This document you will walk you setting up your mobile device(s).

    E-Print Network [OSTI]

    Qiu, Weigang

    Overview: You can use Apple mobile device to access your Exchange account. This document you will walk you setting up your mobile device(s). Setting up an Exchange/ActiveSync connection - Apple i (for example, jsmith@hunter.cuny.edu). · Tap Next on the upper-right corner of the screen. Your Apple

  2. Pollen Removal and Deposition by Honeybee and Bumblebee Visitors to Apple and Almond Author(s): James D. Thomson and Karen Goodell

    E-Print Network [OSTI]

    Thomson, James D.

    Pollen Removal and Deposition by Honeybee and Bumblebee Visitors to Apple and Almond Flowers Author melliferaand Bombusspp. duringsinglevisitsto fourcultivarsof apples(Golden Delicious, Starkrimson fromappleflowersbutBombus deposited more pollen on stigmas. Pollen-collecting bees removed more pollen from apple

  3. APPLE: Malus domestica Borkhauser D. P. Kain and A. Agnello Dogwood borer (DWB); Synanthedon scitula (Harris) N.Y.S. Agric. Expt. Station

    E-Print Network [OSTI]

    Agnello, Arthur M.

    APPLE: Malus domestica Borkhauser D. P. Kain and A. Agnello Dogwood borer (DWB); Synanthedon@nysaes.cornell .edu APPLE, EVALUATION OF VARIOUS TRUNK SPRAYS TO CONTROL BORERS INFESTING BURRKNOTS, 2006 the untreated check. (Table 1) Table 1. Efficacy of insecticides against dogwood borer infesting apple, 2006

  4. Impostazioni Google Apps con client Mail di Apple Mac per l'account di fantasia pinco.panco@uniroma1.it

    E-Print Network [OSTI]

    Di Pillo, Gianni

    Impostazioni Google Apps con client Mail di Apple Mac per l'account di fantasia pinco è ospitato sui server google.com) #12;Impostazioni Google Apps con client Mail di Apple Mac per l Google Apps con client Mail di Apple Mac per l'account di fantasia pinco.panco@uniroma1.it Pag. 3

  5. Theor Appl Genet (2009) 120:8591 DOI 10.1007/s00122-009-1161-8

    E-Print Network [OSTI]

    Burke, John M.

    2009-01-01

    Theor Appl Genet (2009) 120:85­91 DOI 10.1007/s00122-009-1161-8 123 ORIGINAL PAPER Development-mail: shunxue.tang@gmail.com S. J. Knapp e-mail: sjknapp@uga.edu #12;86 Theor Appl Genet (2009) 120:85­91 123

  6. Mac OS X: How to manually add a Windows shared printer http://support.apple.com/kb/ht3049

    E-Print Network [OSTI]

    1 Mac OS X: How to manually add a Windows shared printer http://support.apple.com/kb/ht3049 Mac OS X v10.5 or later 1. Choose System Preferences from the Apple menu. 2. Choose Printers & Scanners. 3

  7. Eur J Appl Physiol (2009) 106:613619 DOI 10.1007/s00421-009-1056-z

    E-Print Network [OSTI]

    Saltzman, Wendy

    2009-01-01

    Eur J Appl Physiol (2009) 106:613­619 DOI 10.1007/s00421-009-1056-z 123 ORIGINAL ARTICLE Day, CA 92407, USA #12;614 Eur J Appl Physiol (2009) 106:613­619 123 as determined by pedometer steps per

  8. The free energy cost of accurate biochemical oscillations

    E-Print Network [OSTI]

    Cao, Yuansheng; Ouyang, Qi; Tu, Yuhai

    2015-01-01

    Oscillation is an important cellular process that regulates timing of different vital life cycles. However, in the noisy cellular environment, oscillations can be highly inaccurate due to phase fluctuations. It remains poorly understood how biochemical circuits suppress phase fluctuations and what is the incurred thermodynamic cost. Here, we study four different types of biochemical oscillations representing three basic oscillation motifs shared by all known oscillatory systems. We find that the phase diffusion constant follows the same inverse dependence on the free energy dissipation per period for all systems studied. This relationship between the phase diffusion and energy dissipation is shown analytically in a model of noisy oscillation. Microscopically, we find that the oscillation is driven by multiple irreversible cycles that hydrolyze the fuel molecules such as ATP; the number of phase coherent periods is proportional to the free energy consumed per period. Experimental evidence in support of this un...

  9. Control of Noise in Chemical and Biochemical Information Processing

    E-Print Network [OSTI]

    Vladimir Privman

    2010-10-09

    We review models and approaches for error-control in order to prevent the buildup of noise when gates for digital chemical and biomolecular computing based on (bio)chemical reaction processes are utilized to realize stable, scalable networks for information processing. Solvable rate-equation models illustrate several recently developed methodologies for gate-function optimization. We also survey future challenges and possible new research avenues.

  10. Prickett and Lonnquist aquifer simulation program for the Apple II minicomputer

    SciTech Connect (OSTI)

    Hull, L.C.

    1983-02-01

    The Prickett and Lonnquist two-dimensional groundwater model has been programmed for the Apple II minicomputer. Both leaky and nonleaky confined aquifers can be simulated. The model was adapted from the FORTRAN version of Prickett and Lonnquist. In the configuration presented here, the program requires 64 K bits of memory. Because of the large number of arrays used in the program, and memory limitations of the Apple II, the maximum grid size that can be used is 20 rows by 20 columns. Input to the program is interactive, with prompting by the computer. Output consists of predicted lead values at the row-column intersections (nodes).

  11. SIAM J. MATRIX ANAL. APPL. Vol. 11, No. 3, pp. 335-360, July 1990

    E-Print Network [OSTI]

    Trefethen, Nick

    was supported by an IBM Faculty Development Award and a National Science Foundation Presidential Young Investigator Award. Research Institute for Advanced Computer Science, Moffett Field, California 94035SIAM J. MATRIX ANAL. APPL. Vol. 11, No. 3, pp. 335-360, July 1990 (C) 1990 Society for Industrial

  12. Appl Phys B (2009) 95: 813824 DOI 10.1007/s00340-008-3306-x

    E-Print Network [OSTI]

    2009-01-01

    infrared QEPAS based ethylene sensor S. Schilt · A.A. Kosterev · F.K. Tittel Received: 29 October 2008Appl Phys B (2009) 95: 813­824 DOI 10.1007/s00340-008-3306-x Performance evaluation of a near / Published online: 2 December 2008 © Springer-Verlag 2008 Abstract A sensor based on quartz

  13. PROGRESS IN PHOTOVOLTAICS: RESEARCH AND APPLICATIONS Prog. Photovolt: Res. Appl. 2006; 14:513531

    E-Print Network [OSTI]

    PROGRESS IN PHOTOVOLTAICS: RESEARCH AND APPLICATIONS Prog. Photovolt: Res. Appl. 2006; 14, Berkeley, CA 94720, USA 2 RWE Schott Solar, 4 Suburban Park Drive, Billerica, MA 01821, USA; Presently at, Golden, CO, USA/Presently: Siliconsultant, P.O. Box 1453, Evergreen, CO 80437, USA 8 BP Solar, 630

  14. Effects of acid rain on apple tree productivity and fruit quality

    SciTech Connect (OSTI)

    Forsline, P.L.; Musselman, R.C.; Kender, W.J.; Dee, R.J.

    1983-01-01

    Mature McIntosh, Empire, and Golden Delicious apple trees (Malus domestica) were sprayed with simulated acid rain solutions in the pH range of 2.5 to 5.5 at full bloom in 1980 and 1981. In 1981, weekly sprays were applied at pH 2.75 and pH 3.25. Necrotic lesions developed on apple petals at pH 2.5 with slight injury appearing at pH 3.0 and 3.5. Apple foliage had no acid rain lesions at any of the pH levels tested. Pollen germination was reduced at pH 2.5 in Empire. Slight fruit set reduction at pH 2.5 was observed in McIntosh. Even at the lowest pH levels no detrimental effects of simulated acid rain were found on apple tree productivity and fruit quality when measured as fruit set, seed number per fruit, and fruit size and appearance.

  15. APPLIED ORGANOMETALLIC CHEMISTRY Appl. Organometal. Chem. 2004; 18: 676683 Main Group Metal Compounds

    E-Print Network [OSTI]

    Leigh, William J.

    APPLIED ORGANOMETALLIC CHEMISTRY Appl. Organometal. Chem. 2004; 18: 676­683 Main Group MetalMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4M1, Canada Received 8 February 2004; Revised 19Master University, 1280 Main Street West, Hamilton, Ontario L8S 4M1, Canada. E-mail: leigh@mcmaster.ca Based on work

  16. Peer-to-Peer Netw. Appl. DOI 10.1007/s12083-014-0301-3

    E-Print Network [OSTI]

    Ã?zkasap, Ã?znur

    January 2014 / Accepted: 23 June 2014 © Springer Science+Business Media New York 2014 Abstract the peers allocate their computational resources, which consume energy, they even end up with increased. #12;Peer-to-Peer Netw. Appl. [1, 16]. In this work, we go one step beyond and propose an alternative

  17. PROGRESS IN PHOTOVOLTAICS: RESEARCH AND APPLICATIONS Prog. Photovolt: Res. Appl. 2006; 14:2543

    E-Print Network [OSTI]

    Anderson, Timothy J.

    PROGRESS IN PHOTOVOLTAICS: RESEARCH AND APPLICATIONS Prog. Photovolt: Res. Appl. 2006; 14 Solar Energy, Inc., 5575 S. Houghton Rd, Tucson, AZ 85747, USA 7 Energy Photovoltaics, Inc., 276 Bakers transport within copper indium gallium sulfoselenide (CIGSS) photovoltaic devices, whose absorber layers

  18. Mobile Netw Appl DOI 10.1007/s11036-008-0133-6

    E-Print Network [OSTI]

    Chen, Min

    Mobile Netw Appl DOI 10.1007/s11036-008-0133-6 Directional Controlled Fusion in Wireless Sensor data fusion and load balancing. We propose a novel directional-controlled fusion (DCF) scheme, consisting of two key algorithms termed as directional control and multipath fusion. By adjusting a key

  19. NUMERICAL LINEAR ALGEBRA WITH APPLICATIONS Numer. Linear Algebra Appl. 2008; 15:115139

    E-Print Network [OSTI]

    De Sterck, Hans

    NUMERICAL LINEAR ALGEBRA WITH APPLICATIONS Numer. Linear Algebra Appl. 2008; 15:115­139 Published and Ulrike Meier Yang2,, 1Department of Applied Mathematics, University of Waterloo, Waterloo, Ont., Canada N2L 3G1 2Center for Applied Scientific Computing, Lawrence Livermore National Laboratory, P.O. Box

  20. Multimed Tools Appl DOI 10.1007/s11042-012-1013-4

    E-Print Network [OSTI]

    Chen, Min

    Multimed Tools Appl DOI 10.1007/s11042-012-1013-4 Towards smart city: M2M communications of reinventing the automobile [8] to illustrate the design rationales for smart city: green, elegant, personalized and human-centric design rationales behind smart city [8]. The technology advances should make

  1. Revised: MASTERS_APPL_ENROLL_TO_PHD-06/04/2014-KCNee FOR ENROLLED STUDENTS ONLY

    E-Print Network [OSTI]

    Maryland, Baltimore County, University of

    Revised: MASTERS_APPL_ENROLL_TO_PHD-06/04/2014-KCNee FOR ENROLLED STUDENTS ONLY APPLICATION FOR ENROLLMENT IN A MASTER'S DEGREE PROGRAM WHO SHOULD USE THIS FORM Admitted PHD students who would like to obtain their masters on the way to their PHD. This form is used in lieu of a new application

  2. NUMERICAL LINEAR ALGEBRA WITH APPLICATIONS Numer. Linear Algebra Appl. 2005; 12:683

    E-Print Network [OSTI]

    NUMERICAL LINEAR ALGEBRA WITH APPLICATIONS Numer. Linear Algebra Appl. 2005; 12:683 Published Numerical Linear Algebra and its Applications The fourth workshop of the ERCIM Working Group on `Matrix Computations and Statistics' and the First International workshop on `Numerical Linear Algebra and its

  3. APPLIED STOCHASTIC MODELS IN BUSINESS AND INDUSTRY Appl. Stochastic Models Bus. Ind., 2005; 21:251263

    E-Print Network [OSTI]

    Shen, Haipeng

    APPLIED STOCHASTIC MODELS IN BUSINESS AND INDUSTRY Appl. Stochastic Models Bus. Ind., 2005; 21 and modelling call centre arrival data. A method is described for analysing such data using singular value, more formal statistical analysis. For example, a short- term forecasting model for call volumes

  4. APPLIED STOCHASTIC MODELS IN BUSINESS AND INDUSTRY Appl. Stochastic Models Bus. Ind., 2006; 22:297311

    E-Print Network [OSTI]

    Shen, Haipeng

    APPLIED STOCHASTIC MODELS IN BUSINESS AND INDUSTRY Appl. Stochastic Models Bus. Ind., 2006; 22 Non-parametric modelling of time-varying customer service times at a bank call centre Haipeng Shen1 are interested in modelling the time-varying pattern of average customer service times at a bank call centre

  5. Appl Phys B (2009) 94: 403409 DOI 10.1007/s00340-008-3352-4

    E-Print Network [OSTI]

    Andersson, Sean B.

    2009-01-01

    in single molecule tracking spec- troscopy [20]. #12;404 S.B. Andersson, T. Sun In this paper we designAppl Phys B (2009) 94: 403­409 DOI 10.1007/s00340-008-3352-4 Linear optimal control for tracking a single fluorescent particle in a confocal microscope S.B. Andersson · T. Sun Received: 13 September 2008

  6. PROGRESS IN PHOTOVOLTAICS: RESEARCH AND APPLICATIONS Prog. Photovolt: Res. Appl. 2009; 17:1133

    E-Print Network [OSTI]

    PROGRESS IN PHOTOVOLTAICS: RESEARCH AND APPLICATIONS Prog. Photovolt: Res. Appl. 2009; 17 Research History of Accelerated and Qualification Testing of Terrestrial Photovoltaic Modules: A Literature-plate terrestrial photovoltaic (PV) modules. An important facet of this subject is the standard module test

  7. MSU Fruit Team Apple Maturity Report 2014 Northwest Region, Report Number 4: October 1, 2014

    E-Print Network [OSTI]

    .3 (12.0 ­ 14.0) Jonna Prince Red Jonagold 100 (100) 20.2 (16.5 ­ 23.0) 2.4 (2 ­ 3) 14.7 (14.0 ­ 15 levels are increasing, these apples are not yet ready for fresh market. Jonna Prince Red Jonagold

  8. Laboratory reproducibility of biochemical markers of bone turnover in clinical practice

    E-Print Network [OSTI]

    Schafer, A. L.; Vittinghoff, E.; Ramachandran, R.; Mahmoudi, N.; Bauer, D. C.

    2010-01-01

    2 ORIGINAL ARTICLE Laboratory reproducibility of biochemicalSummary To determine the laboratory reproducibility of urinedinal and within-run laboratory reproducibility varied

  9. Biochemical Production of Ethanol from Corn Stover: 2008 State of Technology Model

    SciTech Connect (OSTI)

    Humbird, D.; Aden, A.

    2009-08-01

    An update to the FY 2007 assessment of the state of technical research progress toward biochemical process goals, quantified in terms of Minimum Ethanol Selling Price.

  10. Quantifying Stochastic Effects in Biochemical Reaction Networks using Partitioned Leaping

    E-Print Network [OSTI]

    Leonard A. Harris; Aaron M. Piccirilli; Emily R. Majusiak; Paulette Clancy

    2009-07-06

    "Leaping" methods show great promise for significantly accelerating stochastic simulations of complex biochemical reaction networks. However, few practical applications of leaping have appeared in the literature to date. Here, we address this issue using the "partitioned leaping algorithm" (PLA) [L.A. Harris and P. Clancy, J. Chem. Phys. 125, 144107 (2006)], a recently-introduced multiscale leaping approach. We use the PLA to investigate stochastic effects in two model biochemical reaction networks. The networks that we consider are simple enough so as to be accessible to our intuition but sufficiently complex so as to be generally representative of real biological systems. We demonstrate how the PLA allows us to quantify subtle effects of stochasticity in these systems that would be difficult to ascertain otherwise as well as not-so-subtle behaviors that would strain commonly-used "exact" stochastic methods. We also illustrate bottlenecks that can hinder the approach and exemplify and discuss possible strategies for overcoming them. Overall, our aim is to aid and motivate future applications of leaping by providing stark illustrations of the benefits of the method while at the same time elucidating obstacles that are often encountered in practice.

  11. Applications of biochemical processes in geothermal and other industries

    SciTech Connect (OSTI)

    Premuzic, E.T.; Lin, M.S.; Jin, J.Z.

    1994-06-01

    Laboratory studies aimed at the development of economically and technically feasible, and environmentally acceptable technology for the disposal of geothermal sludges and wastes have led to the development of biochemical processes which meet the above conditions. A pilot-scale plant has been constructed and used to identify process variables and optimize processing conditions. The total process is flexible and can be used in several modes of operation which include (1) solubilization and removal of many metals, including radionuclides, from brines and sludges; (2) selective removal of a few metals; (3) concentration of metals; (4) recovery of metals; and (5) recovery of salts. The end product is a silica-type material which meets regulatory requirements, while the aqueous phase meets drinking water standards and can be reinjected and/or used for irrigation. Preliminary engineering studies of the metal and salt recovery technologies have indicated that significant cost benefits could be obtained by means of combined processing. Recent accomplishments in the development of new biochemical technologies will be discussed in this paper.

  12. The Macolumn - the plot thickens. [Review of a Apple Macintosh geologic software package and using a plotter with a Macintosh

    SciTech Connect (OSTI)

    Bushey, A.B. )

    1990-04-01

    Several geologic software packages are for the Apple Macintosh are reviewed along with an section on using a plotter with the Macintosh. The plotter is a CalComp Artisan 1025 8-pen plotter.

  13. SIAM J. APPL. MATH. c 2005 Society for Industrial and Applied Mathematics Vol. 65, No. 6, pp. 19521980

    E-Print Network [OSTI]

    Valkó, Peter

    SIAM J. APPL. MATH. c 2005 Society for Industrial and Applied Mathematics Vol. 65, No. 6, pp. 1952@engr.psu.edu, jwalton@math.tamu.edu). §Department of Petroleum Engineering, Texas A&M University, College Station, TX

  14. Setting up @MyHunter (Office365) -Apple iPhone, iPad, or iPod touch: 1. Tap Settings > Mail, Contacts, Calendars > Add Account.

    E-Print Network [OSTI]

    Qiu, Weigang

    Setting up @MyHunter (Office365) - Apple iPhone, iPad, or iPod touch: 1. Tap Settings > Mail.cuny.edu). 4. Tap Next on the upper-right corner of the screen. Your Apple device will try to find the settings it needs to set up your account. 5. If your Apple device can't find your settings automatically, you

  15. 155:427 CHEMICAL & BIOCHEMICAL ENGINEERING DESIGN AND ECONOMICS I FALL 2015 (3 credits)

    E-Print Network [OSTI]

    Muzzio, Fernando J.

    155:427 CHEMICAL & BIOCHEMICAL ENGINEERING DESIGN AND ECONOMICS I FALL 2015 (3 credits) Professor, 3-5PM (Subodh), C-137 Class representative: Brian Schendt Course description Chemical engineering task during the Spring semester design course (155:428 Chemical & Biochemical Engineering Design

  16. 155:427 CHEMICAL & BIOCHEMICAL ENGINEERING DESIGN AND ECONOMICS I FALL 2014 (3 credits)

    E-Print Network [OSTI]

    Muzzio, Fernando J.

    155:427 CHEMICAL & BIOCHEMICAL ENGINEERING DESIGN AND ECONOMICS I FALL 2014 (3 credits) Professor (Ms. Chaudhury), C-137 Course description Chemical engineering fundamentals are integrated:428 Chemical & Biochemical Engineering Design & Economics II). Course objectives · This is the first of two

  17. Biochemical physics modeling of biological nano-motors

    SciTech Connect (OSTI)

    Santamaría-Holek, I.; López-Alamilla, N. J.

    2014-01-14

    We present a biochemical physics model accounting for the dynamics and energetics of both translational and rotational protein motors. A modified version of the hand-over-hand mechanism considering competitive inhibition by ADP is presented. Transition state-like theory is used to reconstruct the time dependent free-energy landscape of the cycle catalyst process that allows to predicting the number of steps or rotations that a single motor can perform. In addition, following the usual approach of chemical kinetics, we calculate the average translational velocity and also the stopping time of processes involving a collectivity of motors, such as exocytosis and endocytosis processes. Finally, we formulate a stochastic model reproducing very well single realizations of kinesin and rotary ATPases.

  18. Final Technical Report "Multiscale Simulation Algorithms for Biochemical Systems"

    SciTech Connect (OSTI)

    Petzold, Linda R.

    2012-10-25

    Biochemical systems are inherently multiscale and stochastic. In microscopic systems formed by living cells, the small numbers of reactant molecules can result in dynamical behavior that is discrete and stochastic rather than continuous and deterministic. An analysis tool that respects these dynamical characteristics is the stochastic simulation algorithm (SSA, Gillespie, 1976), a numerical simulation procedure that is essentially exact for chemical systems that are spatially homogeneous or well stirred. Despite recent improvements, as a procedure that simulates every reaction event, the SSA is necessarily inefficient for most realistic problems. There are two main reasons for this, both arising from the multiscale nature of the underlying problem: (1) stiffness, i.e. the presence of multiple timescales, the fastest of which are stable; and (2) the need to include in the simulation both species that are present in relatively small quantities and should be modeled by a discrete stochastic process, and species that are present in larger quantities and are more efficiently modeled by a deterministic differential equation (or at some scale in between). This project has focused on the development of fast and adaptive algorithms, and the fun- damental theory upon which they must be based, for the multiscale simulation of biochemical systems. Areas addressed by this project include: (1) Theoretical and practical foundations for ac- celerated discrete stochastic simulation (tau-leaping); (2) Dealing with stiffness (fast reactions) in an efficient and well-justified manner in discrete stochastic simulation; (3) Development of adaptive multiscale algorithms for spatially homogeneous discrete stochastic simulation; (4) Development of high-performance SSA algorithms.

  19. The Macolumn - the Mac gets geophysical. [A review of geophysical software for the Apple Macintosh computer

    SciTech Connect (OSTI)

    Busbey, A.B. )

    1990-02-01

    Seismic Processing Workshop, a program by Parallel Geosciences of Austin, TX, is discussed in this column. The program is a high-speed, interactive seismic processing and computer analysis system for the Apple Macintosh II family of computers. Also reviewed in this column are three products from Wilkerson Associates of Champaign, IL. SubSide is an interactive program for basin subsidence analysis; MacFault and MacThrustRamp are programs for modeling faults.

  20. V-137: Apple Mac OS X update for Java | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs Search USAJobs SearchWater-Savingof EnergyVulnerabilities7: Apple

  1. Modeling the Physical and Biochemical Influence of Ocean Thermal Energy Conversion Plant Discharges into their Adjacent Waters

    Broader source: Energy.gov [DOE]

    Modeling the Physical and Biochemical Influence of Ocean Thermal Energy Conversion Plant Discharges into their Adjacent Waters

  2. Intel-based iMac, Intel-based Mac mini: How to reset the System Mana... http://docs.info.apple.com/article.html?artnum=303446 1 of 1 7/23/2007 2:16 PM

    E-Print Network [OSTI]

    California at Santa Barbara, University of

    Intel-based iMac, Intel-based Mac mini: How to reset the System Mana... http://docs.info.apple.com/article.html?artnum=303446 1 of 1 7/23/2007 2:16 PM Visit the Apple Store online (1-800-MY-APPLE), visit a retail location on an iMac (Early 2006), iMac (Mid 2006), iMac (Late 2006), or Mac mini (Early 2006): From the Apple menu

  3. Apple pith moth Blastodacna atra Prepared by T. Noma, M. Colunga-Garcia, M. Brewer, J. Landis, and A. Gooch as a part of Michigan State University IPM Program and

    E-Print Network [OSTI]

    Isaacs, Rufus

    Apple pith moth Blastodacna atra Prepared by T. Noma, M. Colunga-Garcia, M. Brewer, J. Landis of Agriculture. Michigan State University's invasive species factsheets The apple pith moth is an occasional pest of apple orchards and fruit tree nurseries in Eurasia. Larvae feed inside the twigs and heavy infestations

  4. 04/12/08 10:42Times Higher Education -Education news, resources and university jobs for the academic world -Book of the week: The Atom and the Apple Page 1 sur 3file:///Users/balibar/Desktop/THE.webarchive

    E-Print Network [OSTI]

    Balibar, Sébastien

    for the academic world - Book of the week: The Atom and the Apple Page 1 sur 3file:///Users/balibar/Desktop/THE.webarchive 04 December 2008 Books by academics reviewed by academics. Book of the week: The Atom and the Apple 4 December 2008 A physicist's stories captivate Chris Sachrajda The Atom and the Apple: Twelve Tales from

  5. Pure Appl. Chem., Vol. 82, No. 12, pp. 22472279, 2010. doi:10.1351/PAC-CON-10-09-04

    E-Print Network [OSTI]

    Martin, Jan M.L.

    2247 Pure Appl. Chem., Vol. 82, No. 12, pp. 2247­2279, 2010. doi:10.1351/PAC-CON-10-09-04 © 2010 to the trans form once the UV source is removed. Although this thermal re-isomerization is slow, *Pure Appl

  6. Biochemical Conversion: Using Enzymes, Microbes, and Catalysis to Make Fuels and Chemicals

    SciTech Connect (OSTI)

    2013-07-26

    This fact sheet describes the Bioenergy Technologies Office's biochemical conversion work and processes. BETO conducts collaborative research, development, and demonstration projects to improve several processing routes for the conversion of cellulosic biomass.

  7. Biochemical markers of bone modeling and remodeling in juvenile racehorses at varying mineral intakes 

    E-Print Network [OSTI]

    Eller, Elena Maria

    2007-09-17

    greater than current NRC recommendations provided a protective effect on the developing skeleton of the young racehorse. Additionally, the biochemical markers used in this study were sensitive enough to track daily changes in bone activity resulting from...

  8. BIOENERGY/BIOFUELS/BIOCHEMICALS Chromatographic determination of 1, 4-b-xylooligosaccharides

    E-Print Network [OSTI]

    California at Riverside, University of

    BIOENERGY/BIOFUELS/BIOCHEMICALS Chromatographic determination of 1, 4-b For the majority of lignocellulosic feedstocks for produc- tion of bioethanol and other biofuels, heteroxylans activity [22] or further hydrolyzed into fermentable sugars as platform molecules for biofuels [23

  9. Evaluation of laboratory-scale in-vessel co-composting of tobacco and apple waste

    SciTech Connect (OSTI)

    Kop?i?, Nina Vukovi? Domanovac, Marija; Ku?i?, Dajana; Briški, Felicita

    2014-02-15

    Highlights: • Apple and tobacco waste mixture was efficiently composted during 22 days. • Physical–chemical and microbiological properties of the mixture were suitable the process. • Evaluation of selected mathematical model showed good prediction of the temperature. • The temperature curve was a “mirror image” of the oxygen concentration curve. • The peak values of the temperature were occurred 9.5 h after the peak oxygen consumption. - Abstract: Efficient composting process requires set of adequate parameters among which physical–chemical properties of the composting substrate play the key-role. Combining different types of biodegradable solid waste it is possible to obtain a substrate eligible to microorganisms in the composting process. In this work the composting of apple and tobacco solid waste mixture (1:7, dry weight) was explored. The aim of the work was to investigate an efficiency of biodegradation of the given mixture and to characterize incurred raw compost. Composting was conducted in 24 L thermally insulated column reactor at airflow rate of 1.1 L min{sup ?1}. During 22 days several parameters were closely monitored: temperature and mass of the substrate, volatile solids content, C/N ratio and pH-value of the mixture and oxygen consumption. The composting of the apple and tobacco waste resulted with high degradation of the volatile solids (53.1%). During the experiment 1.76 kg of oxygen was consumed and the C/N ratio of the product was 11.6. The obtained temperature curve was almost a “mirror image” of the oxygen concentration curve while the peak values of the temperature were occurred 9.5 h after the peak oxygen consumption.

  10. Soy Isoflavone Supplementation and Biochemical Recurrence After Curative Treatment for Localized Prostate Cancer

    E-Print Network [OSTI]

    Camey, Sarah

    2013-08-31

    beam radiation include cystitis, hematuria, incontinence, erectile dysfunction, and secondary malignancies (24). Brachytherapy involves the placement of radioactive seeds directly in the prostate (23,24). The seeds contain iodine or cesium..., non-toxic approach to help prevent or delay biochemical recurrence. Soy and soy isoflavones One novel approach to delaying or preventing biochemical recurrence is the use of soy and soy isoflavones. Soy foods contain a class of phytochemicals known...

  11. Characterization of the Support and Drive System of the PETRA III APPLE Undulator

    SciTech Connect (OSTI)

    Bahrdt, J.; Baecker, H.-J.; Frentrup, W.; Gaupp, A.; Gottschlich, S.; Kuhn, C.; Scheer, M.; Schulz, B.; Gast, M.; Englisch, U.; Schoeps, A.; Tischer, M.

    2010-06-23

    Helmholtzzentrum Berlin has built an APPLE II undulator for the storage ring PETRA III. The device has a total length of 5m and a minimum gap of 11mm. The high magnetic forces in particular in the inclined mode have been analyzed by means of finite element methods (FEM). Specific mechanic components such as flexible joints have been optimized to cope with the gap- and shift-dependent 3D-forces and a sophisticated control and drive system has been implemented. After completion of the device, detailed laser interferometer measurements for all operation modes have been performed. The data are compared to the FEM simulations.

  12. V-191: Apple Mac OS X Multiple Vulnerabilities | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustmentsShirleyEnergyThe U.S.Lacledeutilities. The Economics ofConductMultiple vulnerabilitiesApple has

  13. U-022: Apple QuickTime Multiple Vulnerabilities | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankADVANCEDInstallers/ContractorsPhotovoltaicsStateof Energy TwoEvent at the Pu2: Apple QuickTime

  14. V-115: Apple iOS Bugs Let Local Users Gain Elevated Privileges | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs Search USAJobs SearchWater-Savingof Energy 5: Apple iOS Bugs Let

  15. U-264: Apple OS X Lets Remote Users Execute Arbitrary Code and Local Users Gain Elevated Privileges

    Broader source: Energy.gov [DOE]

    Several vulnerabilities were reported in Apple OS X. A remote user can execute arbitrary code on the target system. A remote user can obtain a password hash in certain cases. A local user can obtain elevated privileges on the target system. A local user can obtain password keystrokes.

  16. Multimed Tools Appl (2009) 41:305331 DOI 10.1007/s11042-008-0230-3

    E-Print Network [OSTI]

    Lui, John C.S.

    2009-01-01

    Multimed Tools Appl (2009) 41:305­331 DOI 10.1007/s11042-008-0230-3 Hack-proof synchronization © Springer Science + Business Media, LLC 2008 Abstract Synchronization protocols based on "dead-reckoning" are vulnerable to a popular type of cheat called speed-hack. A speed-hack helps a cheater to gain unfair

  17. PROGRESS IN PHOTOVOLTAICS: RESEARCH AND APPLICATIONS Prog. Photovolt: Res. Appl. 2004; 12:3338 (DOI: 10.1002/pip.525)

    E-Print Network [OSTI]

    Romeo, Alessandro

    PROGRESS IN PHOTOVOLTAICS: RESEARCH AND APPLICATIONS Prog. Photovolt: Res. Appl. 2004; 12 INTRODUCTION T he polycrystalline CdTe/CdS thin-film solar cell is one of the most important photovoltaic,2 Recent measure- ments of the photovoltaic performance of CdTe solar cells irradiated with high

  18. PROGRESS IN PHOTOVOLTAICS: RESEARCH AND APPLICATIONS Prog. Photovolt: Res. Appl. 2004; 12:93111 (DOI: 10.1002/pip.527)

    E-Print Network [OSTI]

    Romeo, Alessandro

    PROGRESS IN PHOTOVOLTAICS: RESEARCH AND APPLICATIONS Prog. Photovolt: Res. Appl. 2004; 12(In,Ga)Se2; thin-films; photovoltaics; solar energy INTRODUCTION P olycrystalline thin-film solar cells the complete solar spectrum for photovoltaic power conversion. There are several chalcopyr

  19. Multimed Tools Appl (2010) 46:207233 DOI 10.1007/s11042-009-0346-0

    E-Print Network [OSTI]

    Fan, Jianping

    2010-01-01

    Multimed Tools Appl (2010) 46:207­233 DOI 10.1007/s11042-009-0346-0 Exploit camera metadata differ from the images that taken by a lifeless device, such as a surveillance camera or a visual sensor retrieval system was built upon the category of interesting regions and the metadata is used for help

  20. J Control Theory Appl 2011 9 (3) 336352 DOI 10.1007/s11768-011-0313-y

    E-Print Network [OSTI]

    Powell, Warren B.

    J Control Theory Appl 2011 9 (3) 336­352 DOI 10.1007/s11768-011-0313-y A review of stochastic on approximate dynamic programming, with the goal of better understanding the theory behind practical algorithms that arise when the actions/controls are vector-valued and possibly continuous. We then describe some recent

  1. Advances in Applied Mathematics and Mechanics Adv. Appl. Math. Mech., Vol. 5, No. 1, pp. 113-130

    E-Print Network [OSTI]

    Lu, Benzhuo

    , Institute of Computational Mathematics and Scientific/Engineering Computing, the National Center in electrostatic potential are small. In contrast to amount of work on the numerical computations of PNP equationsAdvances in Applied Mathematics and Mechanics Adv. Appl. Math. Mech., Vol. 5, No. 1, pp. 113

  2. SIAM J. MATRIX ANAL. APPL. c 2011 Society for Industrial and Applied Mathematics Vol. 32, No. 4, pp. 12511274

    E-Print Network [OSTI]

    Martinsson, Gunnar

    SIAM J. MATRIX ANAL. APPL. c 2011 Society for Industrial and Applied Mathematics Vol. 32, No. 4, pp OF A MATRIX P. G. MARTINSSON Abstract. Randomized sampling has recently been proven a highly efficient admits algebraic operations (matrix-vector multiplications, matrix factorizations, matrix inversion, etc

  3. SIAM J. MATRIX ANAL. APPL. c 2005 Society for Industrial and Applied Mathematics Vol. 27, No. 2, pp. 532546

    E-Print Network [OSTI]

    SIAM J. MATRIX ANAL. APPL. c 2005 Society for Industrial and Applied Mathematics Vol. 27, No. 2, pp. 532­546 LEAST-SQUARES COVARIANCE MATRIX ADJUSTMENT STEPHEN BOYD AND LIN XIAO Abstract. We consider the problem of finding the smallest adjustment to a given symmetric n � n matrix, as measured by the Euclidean

  4. SEARCHING FOR VIDEOS ON APPLE IPAD AND IPHONE Colum Foley, Jinlin Guo, David Scott, Paul Ferguson, Cathal Gurrin

    E-Print Network [OSTI]

    Lee, Hyowon

    the performance of novice versus expert users. Index Terms-- Video search, iPad, iPhone 1. INTRODUCTION Content system with the iPad app. On the iPad, using simple touch commands users can enter search queriesSEARCHING FOR VIDEOS ON APPLE IPAD AND IPHONE Colum Foley, Jinlin Guo, David Scott, Paul Ferguson

  5. Comput. Methods Appl. Mech. Engrg, 191, 20952109 (2002) Hierarchical, Adaptive, Material Point Method for Dynamic Energy Release

    E-Print Network [OSTI]

    Nairn, John A.

    2002-01-01

    Method for Dynamic Energy Release Rate Calculations Honglai Tan and John A. Nairn Material ScienceComput. Methods Appl. Mech. Engrg, 191, 2095­2109 (2002) Hierarchical, Adaptive, Material Point-closure method was developed for use in Material Point Method (MPM) calculations. The method can be used

  6. Structure and biochemical characterization of proliferating cellular nuclear antigen from a parasitic protozoon

    SciTech Connect (OSTI)

    Cardona-Felix, Cesar S.; Lara-Gonzalez, Samuel; Brieba, Luis G.

    2012-02-08

    Proliferating cellular nuclear antigen (PCNA) is a toroidal-shaped protein that is involved in cell-cycle control, DNA replication and DNA repair. Parasitic protozoa are early-diverged eukaryotes that are responsible for neglected diseases. In this work, a PCNA from a parasitic protozoon was identified, cloned and biochemically characterized and its crystal structure was determined. Structural and biochemical studies demonstrate that PCNA from Entamoeba histolytica assembles as a homotrimer that is able to interact with and stimulate the activity of a PCNA-interacting peptide-motif protein from E. histolytica, EhDNAligI. The data indicate a conservation of the biochemical mechanisms of PCNA-mediated interactions between metazoa, yeast and parasitic protozoa.

  7. 0305-0491(95)00119-0 Comp. Biochem. Physiol. Vol. l12B, No. 4, pp. 667-672, 1995

    E-Print Network [OSTI]

    Ahmad, Sajjad

    Pergamon 0305-0491(95)00119-0 Comp. Biochem. Physiol. Vol. l12B, No. 4, pp. 667-672, 1995 Copyright © 1995Elsevier Science Inc. Printed in Great Britain. All rights reserved 0305-0491/95$9.50+ 0; Lipid interactions; Phase transitions; Unsaturation. Comp. Biochem. Physiol. l12B, 667-672, 1995

  8. 3USDA Forest Service Gen.Tech.Rep. PSW-GTR-166. 1998. Biochemical Reactions of Ozone in Plants1

    E-Print Network [OSTI]

    3USDA Forest Service Gen.Tech.Rep. PSW-GTR-166. 1998. Biochemical Reactions of Ozone in Plants1 Abstract Plants react biochemically to ozone in three phases: with constitutive chemicals in the apoplastic, plant reactions with ozone result in constitutive molecules such as the ozonolysis of ethylene

  9. Apparatus and method for converting biomass to feedstock for biofuel and biochemical manufacturing processes

    DOE Patents [OSTI]

    Kania, John; Qiao, Ming; Woods, Elizabeth M.; Cortright, Randy D.; Myren, Paul

    2015-12-15

    The present invention includes improved systems and methods for producing biomass-derived feedstocks for biofuel and biochemical manufacturing processes. The systems and methods use components that are capable of transferring relatively high concentrations of solid biomass utilizing pressure variations between vessels, and allows for the recovery and recycling of heterogeneous catalyst materials.

  10. Molecular C dynamics downstream: The biochemical decomposition sequence and its impact on soil organic

    E-Print Network [OSTI]

    Neff, Jason

    Decomposition Carbon Pyrolysis-GC/MS Disturbance 1. Introduction Soil organic matter (SOM) is an importantMolecular C dynamics downstream: The biochemical decomposition sequence and its impact on soil in spectroscopic and other chemical methods have greatly enhanced our ability to characterize soil organic matter

  11. Frontiers, Opportunities, and Challenges in Biochemical and Chemical Catalysis of CO2 Fixation

    E-Print Network [OSTI]

    Kenis, Paul J. A.

    of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States Department of Chemical and Biochemical Engineering, Departments of Crop Sciences and Plant Complexes That Catalyze CO2 Reduction to Formate via Hydride Transfer 6632 4.3.3. Catalysts with Redox

  12. Molecular & Biochemical Parasitology 136 (2004) 1123 The LPG1 gene family of Leishmania major

    E-Print Network [OSTI]

    Beverley, Stephen M.

    2004-01-01

    Molecular & Biochemical Parasitology 136 (2004) 11­23 The LPG1 gene family of Leishmania major Kai lipophosphoglycan (LPG) is structurally related to that of the smaller glyco- sylinositolphospholipids (GIPLs Galf -transferase (Galf T) LPG1 affected Galf incorporation in LPG but not GIPLs. We hypothesized

  13. Biochemical Engineering Journal 36 (2007) 239249 Dynamic simulation of benzene vapor treatment by

    E-Print Network [OSTI]

    Daugulis, Andrew J.

    2007-01-01

    Biochemical Engineering Journal 36 (2007) 239­249 Dynamic simulation of benzene vapor treatment microorganisms. The system being considered involves the treatment of benzene vapors by Achro- mobacter biotechnology developed to treat waste gases that has shown promise for removing toxic VOCs, such as benzene

  14. Biochemical Engineering Journal 36 (2007) 250261 Dynamic simulation of benzene vapor treatment by a

    E-Print Network [OSTI]

    Daugulis, Andrew J.

    2007-01-01

    Biochemical Engineering Journal 36 (2007) 250­261 Dynamic simulation of benzene vapor treatment for the treatment of benzene waste gases by Achromobacter xylosoxidans Y234 with n-hexadecane as an immiscible, organic phase. Model calibration was performed to account for observed enhancements of benzene

  15. 1438 Biochemical Society Transactions (2012) Volume 40, part 6 Resistance is futile: the bacteriocin model for

    E-Print Network [OSTI]

    Riley, Margaret

    2012-01-01

    , Smith College, Northampton, MA 01063, U.S.A. Abstract Pathogenic bacteria resistant to many or all1438 Biochemical Society Transactions (2012) Volume 40, part 6 Resistance is futile: the bacteriocin model for addressing the antibiotic resistance challenge Margaret A. Riley*1 , Sandra M. Robinson

  16. 538 Biochemical Society Transactions (2013) Volume 41, part 2 Knot localization in proteins

    E-Print Network [OSTI]

    Bigelow, Stephen

    2013-01-01

    538 Biochemical Society Transactions (2013) Volume 41, part 2 Knot localization in proteins Eric J Genomics, University of Lausanne, CH-1015 Lausanne-Dorigny, Switzerland Abstract The backbones of proteins form linear chains. In the case of some proteins, these chains can be characterized as forming linear

  17. The Energy Costs of Insulators in Biochemical Networks John P. Barton

    E-Print Network [OSTI]

    Sontag, Eduardo

    that consume energy, typically in the form of ATP. We hypothesize that better insulation neces- sarily requiresThe Energy Costs of Insulators in Biochemical Networks John P. Barton and Eduardo D. Sontag higher energy consumption. We test this hypothesis through a combined theoretical and computational

  18. Biobased Chemicals Landscape in 2015: What’s the Role of Biochemicals in the Bioeconomy?

    Broader source: Energy.gov [DOE]

    Breakout 3-B: The Changing Landscapes for Biobased Chemicals: A Decade After the Top Value Added Chemicals from Biomass Biobased Chemicals Landscape in 2015: What’s the Role of Biochemicals in the Bioeconomy? Ken Williams, Program Leader/Principal Chemical Engineer, Nature Works, LLC

  19. J. theor. Biol. (1989) 136, 365-377 Metabolic Control Theory and Biochemical Systems Theory

    E-Print Network [OSTI]

    1989-01-01

    J. theor. Biol. (1989) 136, 365-377 Metabolic Control Theory and Biochemical Systems Theory of the objectives and assumptions of metabolic control theory. In particular, the control and elasticity coefficients that play a central role in metabolic control theory are not constants and cannot be treated

  20. Sequencing the Human Genome http://biochem118.stanford.edu/

    E-Print Network [OSTI]

    Brutlag, Doug

    Human Genome Project: Should we do it? · Service, R. F. (2001). The human genome: Objection #1: big Human Genome Project: How should we do it? · Weber, J. L., & Myers, E. W. (1Sequencing the Human Genome http://biochem118.stanford.edu/ Doug Brutlag, Professor Emeritus

  1. Finishing the Human Genome http://biochem118.stanford.edu/

    E-Print Network [OSTI]

    Brutlag, Doug

    ;Public Human Genome Project Strategy http://www.nhgri.nih.gov/ #12;Celera Scaffolds #12;Chromosome 8Finishing the Human Genome http://biochem118.stanford.edu/ Doug Brutlag, Professor Emeritus:Public vs. Celera #12;Finishing Strategy for the Public Genome Project #12;Finished Sequence in 2004

  2. Accurate hybrid stochastic simulation of a system of coupled chemical or biochemical reactions

    E-Print Network [OSTI]

    Minnesota, University of

    Accurate hybrid stochastic simulation of a system of coupled chemical or biochemical reactions reactions, approximates the fast reactions as a continuous Markov process, using a chemical Langevin multiple slow reactions may occur within a time step of the numerical integration of the chemical Langevin

  3. Biochemical characterization of Cdc6/Orc1 binding to the replication origin of the euryarchaeon

    E-Print Network [OSTI]

    Berger, James M.

    Biochemical characterization of Cdc6/Orc1 binding to the replication origin of the euryarchaeon (Cdc6)/Origin Replication Complex subunit 1 (Orc1) proteins share sequence homology with eukaryotic DNA under- stand whether Cdc6/Orc1 functions in an eukaryotic or bacterial-like manner, we have

  4. National Bioenergy Center - Biochemical Platform Integration Project: Quarterly Update, Winter 2010

    SciTech Connect (OSTI)

    Schell, D.

    2011-02-01

    Winter 2011 edition of the National Bioenergy Center's Biochemical Platform Integration Project quarterly newsletter. Issue topics: 33rd Symposium on Biotechnology for Fuels and Chemicals program topic areas; results from reactive membrane extraction of inhibitors from dilute-acid pretreated corn stover; list of 2010 task publications.

  5. AN INTEGRATED LUNG-ON-A-CHIP MICROFLUIDIC PLATFORM WITH REAL-TIME BIOCHEMICAL SENSING

    E-Print Network [OSTI]

    Kassegne, Samuel Kinde

    AN INTEGRATED LUNG-ON-A-CHIP MICROFLUIDIC PLATFORM WITH REAL-TIME BIOCHEMICAL SENSING, without finding it. ­ Lucius Annaeus Seneca #12;v ABSTRACT OF THE THESIS An Integrated Lung for detection. In this research, we replicate the Lung-on- a-Chip platform with a cystic fibrosis cell line

  6. National Bioenergy Center, Biochemical Platform Integration Project: Quarterly Update, Summer 2011 (Newsletter)

    SciTech Connect (OSTI)

    Not Available

    2011-09-01

    Summer 2011 issue of the National Bioenergy Center Biochemical Platform Integration Project quarterly update. Issue topics: evaluating new analytical techniques for measuring soluble sugars in the liquid portion of biomass hydrolysates, and measurement of the fraction of insoluble solids in biomass slurries.

  7. A Biochemical Ocean State Estimate in the Southern1 Ocean Gas Exchange Experiment2

    E-Print Network [OSTI]

    Haine, Thomas W. N.

    of the oceanic31 carbon pool. It influences light penetration with consequences for primary productivity1 A Biochemical Ocean State Estimate in the Southern1 Ocean Gas Exchange Experiment2 S. Dwivedi1 , T. W. N. Haine2 and C. E. Del Castillo3 3 1 Department of Atmospheric and Ocean Sciences, University

  8. Final Technical Report Modeling the Physical and Biochemical Influence of Ocean

    E-Print Network [OSTI]

    -EE0003638 Prepared For THE DEPARTMENT OF ENERGY (DOE): MARINE AND HYDROKINETIC INITIATIVE Prepared By MAKAI of the global OTEC resource dwarfs that of other other marine renewable energy technologies, and OTEC powerFinal Technical Report Modeling the Physical and Biochemical Influence of Ocean Thermal Energy

  9. Probing Iron Accumulation in Sacchromyces cerevisiae Using Integrative Biophysical and Biochemical Techniques 

    E-Print Network [OSTI]

    Miao, Ren

    2012-02-14

    ) was studied. Various biophysical (e.g. Mössbauer, EPR, UV-vis spectroscopy) and biochemical (e.g. Western blots, PCR, enzyme activity assay, etc.) techniques were used to characterize the iron content in yeast mitochondria isolated from several mutants strains...

  10. Artificial Cellulosomes and Arsenic Cleanup: From Single Cell Programming to Synthetic Yeast Consortium

    E-Print Network [OSTI]

    Tsai, Shen-Long

    2011-01-01

    bioprocessing for bioethanol production using Saccharomycesbiomass for bioethanol production, p. 12-14. GMSARNfor cellulosic bioethanol production. Appl Biochem

  11. Biochemical Journal Immediate Publication. Published on 03 Oct 2014 as manuscript BJ20140809THISISNOTTHEVERSIONOFRECORD-seedoi:10.1042/BJ20140809 AcceptedManuscript

    E-Print Network [OSTI]

    Craik, Charles S.

    Biochemical Journal Immediate Publication. Published on 03 Oct 2014 as manuscript BJ20140809 with prior permission and as allowed by law. © 2014 The Authors Journal compilation © 2014 Biochemical Society #12;Biochemical Journal Immediate Publication. Published on 03 Oct 2014 as manuscript BJ20140809

  12. Exploring the Pinhole: Biochemical and Genetic Studies on the Prototype Pinholin, S21 

    E-Print Network [OSTI]

    Pang, Ting

    2011-08-08

    and advice, and great help and support on my writing skills. I would like to thank Dr. Christos Savva for his contribution on the EM analysis of S2168. I would also like to thank Dr. Taehyun Park, for building a great foundation on this project... with opposing functions .................... 12 Genetic and biochemical analysis of the lambda holin S105 .......................................... 15 T4 T, a large-hole holin with a single TMD ................ 18 The mechanism...

  13. A Model Incorporating Some of the Mechanical and Biochemical Factors Underlying Clot Formation and Dissolution in Flowing Blood

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Anand, M.; Rajagopal, K.; Rajagopal, K. R.

    2003-01-01

    Multiple interacting mechanisms control the formation and dissolution of clots to maintain blood in a state of delicate balance. In addition to a myriad of biochemical reactions, rheological factors also play a crucial role in modulating the response of blood to external stimuli. To date, a comprehensive model for clot formation and dissolution, that takes into account the biochemical, medical and rheological factors, has not been put into place, the existing models emphasizing either one or the other of the factors. In this paper, after discussing the various biochemical, physiologic and rheological factors at some length, we develop a modelmore »for clot formation and dissolution that incorporates many of the relevant crucial factors that have a bearing on the problem. The model, though just a first step towards understanding a complex phenomenon, goes further than previous models in integrating the biochemical, physiologic and rheological factors that come into play.« less

  14. Cored Apple Bipolarity : A Global Instability to Convection in Radial Accretion?

    E-Print Network [OSTI]

    R. N. Henriksen; D. Valls-Gabaud

    1993-08-19

    We propose that the prevalence of bipolarity in Young Stellar Objects is due to the fine tuning that is required for spherical accretion of an ambient medium onto a central node.It is shown that there are two steady modes that are more likely than radial accretion, each of which is associated with a hyperbolic central point in the meridional stream lines, and consequently with either an equatorial inflow and an axial ejection or vice versa. In each case the stream lines pass through a thick accretion torus, which is better thought of as a standing pressure wave rather than as a relatively inert Keplerian structure.We base our arguments on a simple analytic example,which is topologi cally generic,wherein each bipolarmode is created by the rebound of accreting matter under the action of the thermal,magnetic,turbulent and centrifugal pressures created in the flow. In both bipolar modes the presence of non-zero angular momentum implies axial regions wherein the pressure is first reduced below the value at infinity and then becomes negative, where the solution fails because rotating material can not enter this region without suction.The model thus has empty stems where the activity of the central source must dominate.So the basic engine of the bipolar flow discussed here is simply the rebound of freely falling material from a thick pressure disc into an axial low pressure region.The low mass,high velocity outflow must be produced in this region by an additional mechanism. This is reminiscent of the cored apple structure observed recently in the very young bipolar source VLA 1623.

  15. Chemical and Structural Features of Plants That Contribute to Biomass Recalcitrance

    E-Print Network [OSTI]

    DeMartini, Jaclyn Diana

    2011-01-01

    Sugar Yields for Biofuel Production. Nat. Biotechnol. 2007;Lignin's Grip on Biofuel Production. Nat. Biotechnol. 2007;Sugar Yields for Biofuel Production. Nat. Biotechnol. 2007;

  16. Aspirin and Statin Nonuse Associated With Early Biochemical Failure After Prostate Radiation Therapy

    SciTech Connect (OSTI)

    Zaorsky, Nicholas G.; Buyyounouski, Mark K.; Li, Tianyu; Horwitz, Eric M.

    2012-09-01

    Purpose: To present the largest retrospective series investigating the effect of aspirin and statins, which are hypothesized to have antineoplastic properties, on biochemical failure (nadir plus 2 ng/mL) after prostate radiation therapy (RT). Methods and Materials: Between 1989 and 2006, 2051 men with clinically localized prostate cancer received definitive RT alone (median dose, 76 Gy). The rates of aspirin use and statin use (defined as any use at the time of RT or during follow-up) were 36% and 34%, respectively. The primary endpoint of the study was an interval to biochemical failure (IBF) of less than 18 months, which has been shown to be the single strongest predictor of distant metastasis, prostate cancer survival, and overall survival after RT. Patient demographic characteristics and tumor staging factors were assessed with regard to associations with the endpoint. Univariate analysis was performed with the {chi}{sup 2} test for categorical variables and the Wilcoxon test for continuous variables. Multivariable analysis was performed with a multiple logistic regression. Results: The median follow-up was 75 months. Univariate analysis showed that an IBF of less than 18 months was associated with aspirin nonuse (P<.0001), statin nonuse (P<.0001), anticoagulant nonuse (P=.0006), cardiovascular disease (P=.0008), and prostate-specific antigen (continuous) (P=.008) but not with Gleason score, age, RT dose, or T stage. On multivariate analysis, only aspirin nonuse (P=.0012; odds ratio, 2.052 [95% confidence interval, 1.328-3.172]) and statin nonuse (P=.0002; odds ratio, 2.465 [95% confidence interval, 1.529-3.974]) were associated with an IBF of less than 18 months. Conclusions: In patients who received RT for prostate cancer, aspirin or statin nonuse was associated with early biochemical failure, a harbinger of distant metastasis and death. Further study is needed to confirm these findings and to determine the optimal dosing and schedule, as well as the relative benefits and risks, of both therapies in combination with RT.

  17. Work with Apple's Rhapsody Operating System which Allows Simultaneous UNIX Program Development, UNIX Program Execution, and PC Application Execution

    E-Print Network [OSTI]

    Don Summers; Chris Riley; Lucien Cremaldi; David Sanders

    2004-12-06

    Over the past decade, UNIX workstations have provided a very powerful program development environment. However, workstations are more expensive than PCs and Macintoshes and require a system manager for day-to-day tasks such as disk backup, adding users, and setting up print queues. Native commercial software for system maintenance and "PC applications" has been lacking under UNIX. Apple's new Rhapsody operating system puts the current MacOS on a NeXT UNIX foundation and adds an enhanced NeXTSTEP object oriented development environment called Yellow Box. Rhapsody simultaneously runs UNIX and commercial Macintosh applications such as word processing or spreadsheets. Thus a UNIX detector Monte Carlo can run for days in the background at the same time as a commercial word processing program. And commercial programs such as Dantz Retrospect are being made available to make disk backup easy under Rhapsody. Apple has announced that in 1999 they intend to be running Rhapsody, or MacOS X as it will be called in the commercial release, on all their newer computers. MacOS X may be of interest to those who have trouble hiring expert UNIX system managers; and to those who would prefer to have a single computer and operating system on their desktop that serves both the needs of UNIX program development and running commercial applications, simultaneously. We present our experiences running UNIX programs and Macintosh applications under the Rhapsody DR2 Developer Release.

  18. Method and apparatus for energy efficient self-aeration in chemical, biochemical, and wastewater treatment processes

    DOE Patents [OSTI]

    Gao, Johnway [Richland, WA; Skeen, Rodney S [Pendleton, OR

    2002-05-28

    The present invention is a pulse spilling self-aerator (PSSA) that has the potential to greatly lower the installation, operation, and maintenance cost associated with aerating and mixing aqueous solutions. Currently, large quantities of low-pressure air are required in aeration systems to support many biochemical production processes and wastewater treatment plants. Oxygen is traditionally supplied and mixed by a compressor or blower and a mechanical agitator. These systems have high-energy requirements and high installation and maintenance costs. The PSSA provides a mixing and aeration capability that can increase operational efficiency and reduce overall cost.

  19. Techno-Economic Analysis of Bioconversion of Methane into Biofuel and Biochemical (Poster)

    SciTech Connect (OSTI)

    Fei, Q.; Tao, L.; Pienkos, P .T.; Guarnieri, M.; Palou-Rivera, I.

    2014-10-01

    In light of the relatively low price of natural gas and increasing demands of liquid transportation fuels and high-value chemicals, attention has begun to turn to novel biocatalyst for conversion of methane (CH4) into biofuels and biochemicals [1]. A techno-economic analysis (TEA) was performed for an integrated biorefinery process using biological conversion of methane, such as carbon yield, process efficiency, productivity (both lipid and acid), natural gas and other raw material prices, etc. This analysis is aimed to identify research challenges as well provide guidance for technology development.

  20. Advanced biochemical processes for geothermal brines FY 1998 annual operating plan

    SciTech Connect (OSTI)

    1997-10-01

    As part of the overall Geothermal Energy Research which is aimed at the development of economical geothermal resources production systems, the aim of the Advanced Biochemical Processes for Geothermal Brines (ABPGB) effort is the development of economic and environmentally acceptable methods for disposal of geothermal wastes and conversion of by-products to useful forms. Methods are being developed for dissolution, separation and immobilization of geothermal wastes suitable for disposal, usable in inert construction materials, suitable for reinjection into the reservoir formation, or used for recovery of valuable metals.

  1. A.G.Ramm, Dynamical Systems Method for solving nonlinear operator Intern Journ. Appl Math Sci., 1, (2004), 97-110.

    E-Print Network [OSTI]

    2004-01-01

    454/,/,/, A.G.Ramm, Dynamical Systems Method for solving nonlinear operator equations, Intern Journ. Appl Math Sci., 1, (2004), 97-110. #12;Dynamical Systems Method for solving nonlinear operator operators. 1 Introduction In this paper a version of the DSM, Dynamical Systems Method, is proposed

  2. When worlds collide - Mac to MS-DOS. [Data transfer to and from Apple Macintosh computers and MS-DOS based personal computers

    SciTech Connect (OSTI)

    Busbey, A.B.

    1989-04-01

    A number of methods and products, both hardware and software, to allow data exchange between Apple Macintosh computers and MS-DOS based systems. These included serial null modem connections, MS-DOS hardware and/or software emulation, MS-DOS disk-reading hardware and networking.

  3. IOP PUBLISHING JOURNAL OF OPTICS A: PURE AND APPLIED OPTICS J. Opt. A: Pure Appl. Opt. 9 (2007) doi:10.1088/1464-4258/9/9/E01

    E-Print Network [OSTI]

    Zheludev, Nikolay

    2007-01-01

    and includes negative index materials, 2D and 3D photonic bandgap structures, light in confined geometries physicists were asking what could be learnt from the microwave community's experience in structured materialsIOP PUBLISHING JOURNAL OF OPTICS A: PURE AND APPLIED OPTICS J. Opt. A: Pure Appl. Opt. 9 (2007) doi

  4. Acta Appl.Math., 106, N3, (2009), 473-499. Dynamical Systems Gradient method for solving nonlinear equations with monotone

    E-Print Network [OSTI]

    2009-01-01

    Acta Appl.Math., 106, N3, (2009), 473-499. Dynamical Systems Gradient method for solving nonlinear@math.ksu.edu 1 #12;Dynamical Systems Gradient method for solving nonlinear equations with monotone operators N. S A version of the Dynamical Systems Gradient Method for solving ill-posed nonlinear monotone operator

  5. First Report of Nectria galligena Causing European Canker of Apple Trees in Ontario. A. R. Biggs, Agriculture Canada Research Station, Vineland Station, Ontario LOR 2EO. Plant

    E-Print Network [OSTI]

    Biggs, Alan R.

    First Report of Nectria galligena Causing European Canker of Apple Trees in Ontario. A. R. Biggs, Agriculture Canada Research Station, Vineland Station, Ontario LOR 2EO. Plant Disease 69:1007, 1985. Accepted galligena Bres. was first observed in Wentworth County, Ontario, Canada, in March 1985. The fungus had been

  6. Mac mini: How to Reset the PMU http://docs.info.apple.com/article.html?artnum=300574 1 of 2 7/23/2007 2:06 PM

    E-Print Network [OSTI]

    California at Santa Barbara, University of

    Mac mini: How to Reset the PMU http://docs.info.apple.com/article.html?artnum=300574 1 of 2 7/23/2007 2:06 PM Mac mini: How to Reset the PMU The Power Management Unit (PMU) is an integrated circuit (computer chip) typically found on a computer's logic board. As its name implies, the PMU is responsible

  7. Impact of chronic lead poisoning on the hematological and biochemical profiles of a fish, Barbus conchonius (Ham)

    SciTech Connect (OSTI)

    Tewari, H.; Gill, S.T.; Pant, J.

    1987-05-01

    The contamination of natural waters by lead is mostly caused by a variety of anthropogenic activities related to increased mining operations and industrial uses of this metal. Adverse effects of lead poisoning in the fishes have been reported with references to both hematological and biochemical variables. The aim of present investigation was to study the effects of chronically administered sublethal levels of inorganic lead on the hematological and biochemical profiles of widely distributed freshwater fish, Barbus conchonius. The variables such as erythrocyte numbers, hemoglobin, hematocrit, mean corpuscular volume, blood glucose, glycogen in liver, skeletal muscles, and myocardium, and cholesterol in blood, liver, ovary, and testes were evaluated.

  8. Study of Row Phase Dependent Skew Quadrupole Fields in Apple-II Type EPUs at the ALS

    SciTech Connect (OSTI)

    Steier, C.; Marks, S.; Prestemon, Soren; Robin, David; Schlueter, Ross; Wolski, Andrzej

    2004-05-07

    Since about 5 years, Apple-II type Elliptically Polarizing Undulators (EPU) have been used very successfully at the ALS to generate high brightness photon beams with arbitrary polarization. However, both EPUs installed so far cause significant changes of the vertical beamsize, especially when the row phase is changed to change the polarization of the photons emitted. Detailed measurements indicate this is caused by a row phase dependent skew quadrupole term in the EPUs. Magnetic measurements revealed the same effect for the third EPU to be installed later this year. All measurements to identify and quantify the effect with beam will be presented, as well as some results of magnetic bench measurements and numeric field simulations.

  9. Biochemical Journal Immediate Publication. Published on 23 Nov 2010 as manuscript BJ20101691THISISNOTTHEVERSIONOFRECORD-seedoi:10.1042/BJ20101691 AcceptedManuscript

    E-Print Network [OSTI]

    Gleeson, Joseph G.

    Biochemical Journal Immediate Publication. Published on 23 Nov 2010 as manuscript BJ20101691 with prior permission and as allowed by law. © 2010 The Authors Journal compilation © 2010 Portland Press Limited #12;Biochemical Journal Immediate Publication. Published on 23 Nov 2010 as manuscript BJ20101691

  10. Identification of Catalysts and Materials for a High-Energy Density Biochemical Fuel Cell: Cooperative Research and Development Final Report, CRADA Number CRD-09-345

    SciTech Connect (OSTI)

    Ghirardi, M.; Svedruzic, D.

    2013-07-01

    The proposed research attempted to identify novel biochemical catalysts, catalyst support materials, high-efficiency electron transfer agents between catalyst active sites and electrodes, and solid-phase electrolytes in order to maximize the current density of biochemical fuel cells that utilize various alcohols as substrates.

  11. 210 Biochemical Society Transactions (2012) Volume 40, part 1 PKA phosphorylation of the small heat-shock

    E-Print Network [OSTI]

    Scott, John D.

    2012-01-01

    , are less frequently induced by heat stress, and several family members, such as Hsp27 and B210 Biochemical Society Transactions (2012) Volume 40, part 1 PKA phosphorylation of the small heat The small heat-shock protein Hsp20 (heat-shock protein 20), also known as HspB6, has been shown to protect

  12. Biochemical Characterization and Mass Spectrometric Disulfide Bond Mapping of Periplasmic -Amylase MalS of Escherichia coli*

    E-Print Network [OSTI]

    Rippe, Karsten

    Biochemical Characterization and Mass Spectrometric Disulfide Bond Mapping of Periplasmic -Amylase Republic of Germany Periplasmic -amylase of Escherichia coli, the malS gene product, hydrolyzes linear-nitrophenylhexaoside hydrolyzed per min per mg of protein. Amylase activity was optimal at pH 8 and was dependent on divalent

  13. Eur. J. Biochem. 85, 529-534 (1978) X-Ray and Neutron Small-Angle Scattering Studies

    E-Print Network [OSTI]

    1978-01-01

    Eur. J. Biochem. 85, 529-534 (1978) X-Ray and Neutron Small-Angle Scattering Studies of the Complex-ray and neutron scattering techniques. In this work, we concentrated mainly on radius of gyration analyses and a neutron scattering experiment is performed in 21-Iz0 solvent. This decrease simply reflects the fact

  14. Neutral Lipid Extraction by the Method of Bligh-Dyer (Bligh and Dyer, Can. J. Biochem. Physiol. 37, 922 (1959))

    E-Print Network [OSTI]

    Pike, Linda J.

    1959-01-01

    Neutral Lipid Extraction by the Method of Bligh-Dyer (Bligh and Dyer, Can. J. Biochem. Physiol. 37 for 1 min at low speed. 5. Remove top layer and transfer to a new glass tube. Add 1 ml CHCl3 and re-extract as above by vortexing and phase separation. 6. Aspirate the top layer from this second extraction

  15. Metal-ion rescue revisited: Biochemical detection of site-bound metal ions important for RNA folding

    E-Print Network [OSTI]

    Das, Rhiju

    Metal-ion rescue revisited: Biochemical detection of site-bound metal ions important for RNA-dimensional architectures of RNA molecules, divalent metal ions populate specific locations, shedding their water molecules make essential contributions to function. Defining the locations of these site-bound metal ions remains

  16. Biochemical Control With Radiotherapy Improves Overall Survival in Intermediate and High-Risk Prostate Cancer Patients Who Have an Estimated 10-Year Overall Survival of >90%

    SciTech Connect (OSTI)

    Herbert, Christopher; Liu, Mitchell; Tyldesley, Scott; Morris, W. James; Joffres, Michel; Khaira, Mandip; Kwan, Winkle; Moiseenko, Vitali; Pickles, Thomas

    2012-05-01

    Purpose: To identify subgroups of patients with carcinoma of the prostate treated with radical radiotherapy that have improved overall survival when disease is biochemically controlled. Methods and Materials: A cohort of 1,060 prostate cancer patients treated with radical radiotherapy was divided into nine subgroups based on National Comprehensive Cancer Network risk category and estimated 10-year overall survival (eOS 10y) derived from the age adjusted Charlson Comorbidity Index. Patients with and without biochemical control were compared with respect to overall survival. Actuarial estimates of overall survival were calculated using the Kaplan-Meier method. Univariate and multivariate Cox proportional hazards models were used for analysis of overall survival. Results: Median follow-up was 125 months (range, 51-176 months). Only the subgroups with high or intermediate risk disease and an eOS 10y of >90% had a statistically significantly improved overall survival when prostate cancer was biochemically controlled. In all other groups, biochemical control made no significant difference to overall survival. In the subgroup with high-risk disease and eOS 10y >90%, actuarial overall survival was 86.3% (95% confidence interval [CI] 78.5%-94.1%) and 62.1% (95% CI 52.9%-71.3%) for patients with biochemical control and biochemical relapse respectively (p = 0.002). In the intermediate risk group with eOS >90%, actuarial overall survival was 95.3% (95% CI 89.0%-100%) and 79.8% (95% CI 68.0%-91.6%) for biochemically controlled and biochemically relapsed patients (p = 0.033). On multivariate analysis, National Comprehensive Cancer Network risk group (p = 0.005), biochemical control (p = 0.033) and eOS 10y (p < 0.001) were statistically significant. Conclusion: Biochemical control translates into improved overall survival in patients with high or intermediate risk disease and an estimated 10-year overall survival of >90%.

  17. Purification of 1-aminocyclopropane-1-carboxylate synthase from apple fruits using s-adenosyl (3,4 sup 14 C)-methionine (SAM) as a probe

    SciTech Connect (OSTI)

    Yip, Wingkip; Dong, Jianguo,; Yang, Shang Fa )

    1989-04-01

    Tomato ACC synthase is inactivated by its substrate SAM, with the moiety of aminobutyrate being covalently linked to ACC synthase during the catalytic reactions. A partial purified ACC synthase (the catalytic activity 100 {mu}mol/h{center dot}mg protein) from pellets of apple extract was incubated with (3,4{sup 14}C) SAM. Only one radioactive peak was revealed in a C-4 reverse phase HPLC and one radioactive band on SDS-PAGE with an M.W. of 48 kDa. Apple ACC synthase in native form is resistant to V8, {alpha}-chromtrypsin and carboxylpeptidase A digestion, but effectively inactivated by trypsin and ficin, as demonstrated by both the activity assay and SAM labeling. The radioactive protein cut from the SDS-PAGE was injected to three mice, two of the mice showed responses to the protein in western blot analysis. The antibodies from mice is currently under characterization.

  18. Defining biochemical failure after radiotherapy with and without androgen deprivation for prostate cancer

    SciTech Connect (OSTI)

    Buyyounouski, Mark K. [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States)]. E-mail: mark.buyyounouski@fccc.edu; Hanlon, Alexandra L. [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Eisenberg, Debra F. [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Horwitz, Eric M. [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Feigenberg, Steven J. [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Uzzo, Robert G. [Department of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Pollack, Alan [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States)

    2005-12-01

    Purpose: To compare several characteristics of alternative definitions of biochemical failure (BF) in men with extended follow-up after radiotherapy (RT) with or with androgen deprivation therapy (ADT) for prostate cancer. Methods and Materials: From December 1, 1991, to April 30, 1998, 688 men with Stage T1c-T3NX-N0M0 prostate cancer received RT alone (n = 586) or RT plus ADT (n = 102) with a minimal follow-up of 4 years and five or more 'ADT-free' posttreatment prostate-specific antigen levels. BF was defined by three methods: (1) the ASTRO definition (three consecutive rises in prostate-specific antigen level); (2) a modified American Society for Therapeutic Radiology Oncology (ASTRO) definition requiring two additional consecutive rises when a decline immediately subsequent to three consecutive rises occurred; and (3) the 'Houston' or nadir plus 2-ng/mL definition (a rise of at least 2 ng/mL greater than the nadir). The sensitivity, specificity, positive predictive value, negative predictive value, and overall accuracy were determined for each using clinical progression as the endpoint. Furthermore, the misclassification rates for a steadily rising prostate-specific antigen level, ability to satisfy the proportional hazards (RT with or without ADT), effects of short follow-up, and intervals to the diagnosis of BF were compared. Results: The misclassification rate for BF using the nadir plus 2-ng/mL definition was 2% for RT alone and 0% for RT plus ADT compared with 0% and 0% for the modified ASTRO definition, and 5% and 23% for the ASTRO definition, respectively. The hazard rates for RT alone and RT plus ADT were proportional only for the nadir plus 2 ng/mL definition and seemingly unaffected by the length of follow-up. For RT with or without ADT, the nadir plus 2 ng/mL definition was the most specific (RT, 80% vs. RT plus ADT, 75%) with the greatest positive predictive value (RT, 36% vs. RT plus ADT, 25%) and overall accuracy (RT, 81% vs. RT plus ADT, 77%). A greater proportion of BF was diagnosed in the first 2 years of follow-up with the nadir plus 2 ng/mL definition compared with the ASTRO definition (13% vs. 5%, p = 0.0138, chi-square test). Conclusion: The nadir plus 2 ng/mL definition was the best predictor of sustained, true, biochemical, and clinical failure, and was not affected by the use of ADT or follow-up length.

  19. Method for detection of long-lived radioisotopes in small biochemical samples

    DOE Patents [OSTI]

    Turteltaub, Kenneth W. (Livermore, CA); Vogel, John S. (Union City, CA); Felton, James S. (Danville, CA); Gledhill, Barton L. (Alamo, CA); Davis, Jay C. (Livermore, CA)

    1994-01-01

    Disclosed is a method for detection of long-lived radioisotopes in small bio-chemical samples, comprising: a. selecting a biological host in which radioisotopes are present in concentrations equal to or less than those in the ambient biosphere, b. preparing a long-lived radioisotope labeled reactive chemical specie, c. administering said chemical specie to said biologist host in doses sufficiently low to avoid significant overt damage to the biological system thereof, d. allowing a period of time to elapse sufficient for dissemination and interaction of said chemical specie with said host throughout said biological system of said host, e. isolating a reacted fraction of the biological substance from said host in a manner sufficient to avoid contamination of said substance from extraneous sources, f. converting said fraction of biological substance by suitable means to a material which efficiently produces charged ions in at least one of several possible ion sources without introduction of significant isotopic fractionation, and, g. measuring the radioisotope concentration in said material by means of direct isotopic counting.

  20. Monolithic piezoelectric sensor (MPS) for sensing chemical, biochemical and physical measurands

    DOE Patents [OSTI]

    Andle, Jeffrey C. (Bangor, ME); Lec, Ryszard M. (Orono, ME)

    2000-01-01

    A piezoelectric sensor and assembly for measuring chemical, biochemical and physical measurands is disclosed. The piezoelectric sensor comprises a piezoelectric material, preferably a crystal, a common metal layer attached to the top surface of the piezoelectric crystal, and a pair of independent resonators placed in close proximity on the piezoelectric crystal such that an efficacious portion of acoustic energy couples between the resonators. The first independent resonator serves as an input port through which an input signal is converted into mechanical energy within the sensor and the second independent resonator serves an output port through which a filtered replica of the input signal is detected as an electrical signal. Both a time delay and an attenuation at a given frequency between the input signal and the filtered replica may be measured as a sensor output. The sensor may be integrated into an assembly with a series feedback oscillator and a radio frequency amplifier to process the desired sensor output. In the preferred embodiment of the invention, a selective film is disposed upon the grounded metal layer of the sensor and the resonators are encapsulated to isolate them from the measuring environment. In an alternative embodiment of the invention, more than two resonators are used in order to increase the resolution of the sensor.

  1. Evaluation and comparison of biochemical markers of anthropogenic stress in the sheepshead minnow

    SciTech Connect (OSTI)

    Stuck, K.; Furst, H.; Boyd, C.; Walker, W.; Watts, S.; Mayer, F.

    1995-12-31

    The utility of bioenergetic and growth-rate indices for assessing chemically induced stress in larval and juvenile sheepshead minnows (Cyprinodon variegatus) was investigated. Viable embryos were exposed to zinc chloride at concentrations of 0.6, 1.5 and 3.8 ppm over a period of 28 days. Samples were collected from each exposure group and a unexposed control group on days 7, 14 and 28 of the study. Individual fish were measured and weighed wet. Triacylglycerol (TAG) and sterol content of exposed and control fish was determined using a FID/TLC latroscan system, polyamines were quantified by HPLC, nucleic acids levels were determined using an ethidium bromide fluorescence technique, and % tissue solids were estimated by dry weight analysis. A significant reduction in the TAG:sterol ratio was observed among fish exposed to 3.8 ppm ZnCl for 28 days. TAG:sterol was significantly correlated with growth-rate, % tissue solids, and concentration of ZnCl. RNA:DNA and polyamine (putrescine: spermine) ratios were significantly higher among day 7 control and exposed fish than those obtained from fish collected on days 14 and 28. RNA:DNA ratios of fish exposed to 3.8 ppm ZnCl for 28 days were significantly lower than those of fish in the control group. Polyamine ratios from fish exposed to 3.8 ppm ZnCl were significantly lower than control fish after 14 days of exposure. There was a significant correlation between polyamine ratios and concentration of ZnCl. TAG:sterol, RNA:DNA, and polyamine ratios can be used to biochemically assess anthropogenic stress; however, due to ontogenetic changes, these indicators are applicable only after endogenous yolk reserves have been depleted.

  2. COATINGS FOR PROTECTION OF EQUIPMENT FOR BIOCHEMICAL PROCESSING OF GEOTHERMAL RESIDUES: PROGRESS REPORT FY 97

    SciTech Connect (OSTI)

    ALLAN,M.L.

    1997-11-01

    Thermal sprayed ethylene methacrylic acid (EMAA) and ethylene tetrafluoroethylene (ETFE), spray-and-bake ETFE and polyvinylidene fluoride (PVDF) and brushable ceramic-epoxy coatings were evaluated for corrosion protection in a biochemical process to treat geothermal residues. The findings are also relevant to other moderate temperature brine environments where corrosion is a problem. Coupon, Atlas cell, peel strength, cathodic disbondment and abrasion tests were performed in aggressive environments including geothermal sludge, hypersaline brine and sulfur-oxidizing bacteria (Thiobadus ferrooxidans) to determine suitability for protecting storage tanks and reaction vessels. It was found that all of the coatings were resistant to chemical attack and biodegradation at the test temperature of 55 C. The EMAA coatings protected 316L stainless steel from corrosion in coupon tests. However, corrosion of mild steel substrates thermal sprayed with EMAA and ETFE occurred in Atlas cell tests that simulated a lined reactor operating environment and this resulted in decreased adhesive strength. Peel tests to measure residual adhesion revealed that failure mode was dependent on exposure conditions. Long-term tests on the durability of ceramic-epoxy coatings in brine and bacteria are ongoing. Initial indications are that this coating has suitable characteristics. Abrasion tests showed that the ceramic-epoxy had good resistance to the abrasive effects of sludge. Thermal sprayed EMAA coatings also displayed abrasion resistance. Cathodic disbondment tests in brine at room temperature indicated that EMAA coatings are resistant to disbondment at applied potentials of {minus}780 to {minus}1,070 mV SCE for the test conditions and duration. Slight disbondment of one specimen occurred at a potential of {minus}1,500 mV SCE. The EMAA may be suited to use in conjunction with cathodic protection although further long-term, higher temperature testing would be needed.

  3. Coatings for protection of equipment for biochemical processing of geothermal residues: Progress report FY`97

    SciTech Connect (OSTI)

    Allan, M.L.

    1997-11-01

    Thermal sprayed ethylene methacrylic acid (EMAA) and ethylene tetrafluoroethylene (ETFE), spray-and-bake ETFE and polyvinylidene fluoride (PVDF) and brushable ceramic-epoxy coatings were evaluated for corrosion protection in a biochemical process to treat geothermal residues. Coupon, Atlas cell, peel strength, cathodic disbondment and abrasion tests were performed in aggressive environments including geothermal sludge, hypersaline brine and sulfur-oxidizing bacteria (Thiobacillus ferrooxidans) to determine suitability for protecting storage tanks and reaction vessels. It was found that all of the coatings were resistant to chemical attack and biodegradation at the test temperature of 55 C. The EMAA coatings protected 316L stainless steel from corrosion in coupon tests. However, corrosion of mild steel substrates thermal sprayed with EMAA and ETFE occurred in Atlas cell tests that simulated a lined reactor operating environment and this resulted in decreased adhesive strength. Peel tests to measure residual adhesion revealed that failure mode was dependent on exposure conditions. Abrasion tests showed that the ceramic-epoxy had good resistance to the abrasive effects of sludge. Thermal sprayed EMAA coatings also displayed abrasion resistance. Cathodic disbondment tests in brine at room temperature indicated that EMAA coatings are resistant to disbondment at applied potentials of {minus}780 to {minus}1,070 mV SCE for the test conditions and duration. Slight disbondment of one specimen occurred at a potential of {minus}1,500 mV SCE. The EMAA may be suited to use in conjunction with cathodic protection although further long-term, higher temperature testing would be needed.

  4. 320 Biotechnol. Prog. 1994, 10, 320-326 oseph J. Vallinot an Gregory Stephanopoulos*

    E-Print Network [OSTI]

    Vallino, Joseph J.

    (FP) to a standard fermentation during the initial period of lysine overproduction. No significant no pyruvate carboxylase activity was detected in crudecellextracts of C. glutamic- um

  5. J Ind Microbiol Biotechnol DOI 10.1007/s10295-014-1548-7

    E-Print Network [OSTI]

    Wood, Thomas K.

    of infrastructure for the use of compressed natural gas [33] are spearheading the use of gas-to-liquid (GTL] but also by far the largest constituent of natural gas deposits. Global proven natural gas resources have in natural gas reserves in the United States from 2012 to 2040 [5]. Over the last ten reported years (ending

  6. Biotechnology DOI 10.1002/biot.201000129 Biotechnol. J. 2010, 5, 660670

    E-Print Network [OSTI]

    sources. Microalgae hold promise as a source of renew- able energy. Algae-derived hydrogen, methane, tri- acylglycerols,and ethanol all serve as potential ma- terials for biofuels [3­6]. For example, depending on production conditions, Schizochytrium sp. and Botryococcus braunii may yield 50­77% and 25­75% oil by mass

  7. Biotechnology DOI 10.1002/biot.201100445 Biotechnol. J. 2011, 6, 12981299

    E-Print Network [OSTI]

    change, environmental deterio- ration, energy crisis, shortage of natural resources, threats to public of natural re- sources, to improve public per- ceptions and education, to facil- itate exchange of scholars Shimizu [4]. The effects of culture en- vironments on cell metabo- lism via global regulators with sigma

  8. Molecular Siganture and Sources of Biochemical Recalcitrance of Organic C in Amozonian Dark Earths

    SciTech Connect (OSTI)

    Solomon,D.; Lehmann, J.; Thies, J.; Schafer, T.; Liang, B.; Kinyangi, J.; Neves, E.; Peterson, J.; Liuzao, F.; Skjemstad, J.

    2007-01-01

    Amazonian Dark Earths (ADE) are a unique type of soils developed through intense anthropogenic activities that transformed the original soils into Anthrosols throughout the Brazilian Amazon Basin. We conducted a comparative molecular-level investigation of soil organic C (SOC) speciation in ADE (ages between 600 and 8700 years B.P.) and adjacent soils using ultraviolet photo-oxidation coupled with {sup 13}C cross polarization-magic angle spinning nuclear magnetic resonance (CP-MAS NMR), synchrotron-based Fourier transform infrared-attenuated total reflectance (Sr-FTIR-ATR) and C (1s) near edge X-ray absorption fine structure (NEXAFS) spectroscopy to obtain deeper insights into the structural chemistry and sources of refractory organic C compounds in ADE. Our results show that the functional group chemistry of SOC in ADE was considerably different from adjacent soils. The SOC in ADE was enriched with: (i) aromatic-C structures mostly from H- and C-substituted aryl-C, (ii) O-rich organic C forms from carboxylic-C, aldehyde-C, ketonic-C and quinine-C, and (iii) diverse group of refractory aliphatic-C moieties. The SOC in adjacent soils was predominantly composed of O-alkyl-C and methoxyl-C/N-alkyl-C structures and elements of labile aliphatic-C functionalities. Our study suggests that the inherent molecular structures of organic C due to selective accumulation of highly refractory aryl-C structures seems to be the key factor for the biochemical recalcitrance and stability of SOC in ADE. Anthropogenic enrichment with charred carbonaceous residues from biomass-derived black C (BC) is presumed to be the precursor of these recalcitrant polyaromatic structures. Our results also highlight the complementary role that might be played by organic C compounds composed of O-containing organic C moieties and aliphatic-C structures that persisted for millennia in these anthropic soils as additional or secondary sources of chemical recalcitrance of SOC in ADE. These organic C compounds could be the products of: (i) primary recalcitrant biomolecules from non-BC sources or (ii) secondary processes involving microbial mediated oxidative or extracellular neoformation reactions of SOC from BC and non-BC sources; and stabilized through physical inaccessibility to decomposers due to sorption onto the surface or into porous structures of BC particles, selective preservation or through intermolecular interactions involving clay and BC particles.

  9. Structural And Biochemical Characterization of the Therapeutic A. Variabilis Phenylalanine Ammonia Lyase

    SciTech Connect (OSTI)

    Wang, L.; Gamez, A.; Archer, H.; Abola, E.E.; Sarkissian, C.N.; Fitzpatrick, P.; Wendt, D.; Zhang, Y.; Vellard, M.; Bliesath, J.; Bell, S.; Lemont, J.; Scriver, C.R.; Stevens, R.C.

    2009-05-26

    We have recently observed promising success in a mouse model for treating the metabolic disorder phenylketonuria with phenylalanine ammonia lyase (PAL) from Rhodosporidium toruloides and Anabaena variabilis. Both molecules, however, required further optimization in order to overcome problems with protease susceptibility, thermal stability, and aggregation. Previously, we optimized PAL from R. toruloides, and in this case we reduced aggregation of the A. variabilis PAL by mutating two surface cysteine residues (C503 and C565) to serines. Additionally, we report the structural and biochemical characterization of the A. variabilis PAL C503S/C565S double mutant and carefully compare this molecule with the R. toruloides engineered PAL molecule. Unlike previously published PAL structures, significant electron density is observed for the two active-site loops in the A. variabilis C503S/C565S double mutant, yielding a complete view of the active site. Docking studies and N-hydroxysuccinimide-biotin binding studies support a proposed mechanism in which the amino group of the phenylalanine substrate is attacked directly by the 4-methylidene-imidazole-5-one prosthetic group. We propose a helix-to-loop conformational switch in the helices flanking the inner active-site loop that regulates accessibility of the active site. Differences in loop stability among PAL homologs may explain the observed variation in enzyme efficiency, despite the highly conserved structure of the active site. A. variabilis C503S/C565S PAL is shown to be both more thermally stable and more resistant to proteolytic cleavage than R. toruloides PAL. Additional increases in thermal stability and protease resistance upon ligand binding may be due to enhanced interactions among the residues of the active site, possibly locking the active-site structure in place and stabilizing the tetramer. Examination of the A. variabilis C503S/C565S PAL structure, combined with analysis of its physical properties, provides a structural basis for further engineering of residues that could result in a better therapeutic molecule.

  10. Interval to Biochemical Failure Highly Prognostic for Distant Metastasis and Prostate Cancer-Specific Mortality After Radiotherapy

    SciTech Connect (OSTI)

    Buyyounouski, Mark K. [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States)], E-mail: mark.buyyounouski@fccc.edu; Hanlon, Alexandra L.; Horwitz, Eric M.; Pollack, Alan [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States)

    2008-01-01

    Purpose: Few biochemical parameters have been related to mortality. The present study examined the clinical utility of the interval to biochemical failure (IBF) as a prognostic factor for distant metastasis (DM) and prostate cancer-specific mortality (PCSM) after radiotherapy. Methods and Materials: The study group consisted of 211 T1c-T3Nx-N0M0 patients who had experienced BF among 1,174 men treated with three-dimensional conformal radiotherapy alone. Biochemical failure was defined as a post-treatment prostate-specific antigen (PSA) level of at, or greater than, the PSA nadir plus 2 ng/mL. Cox proportional hazards modeling was used to identify independent predictors of DM and PCSM on multivariate analysis. Results: An IBF of <18 months was independently predictive for DM (p = 0.008), as was a Gleason score of 7-10 (p = 0.0005), PSA nadir {>=}2 ng/mL (p = 0.04), and decreasing radiation dose (p = 0.02) on multivariate analysis, including increasing pretreatment PSA level, PSA nadir {>=}2.5 ng/mL, PSA doubling time of <3 months, and Stage T3 disease. An IBF of <18 months was the only predictor of PCSM (p = 0.0003) in the same model. The actuarial 5-year DM rate for an IBF of <18 vs. {>=}18 months was 52% vs. 20% (p < 0.0001), and the actuarial PCSM rate was 36% vs. 6%, respectively (p = 0.0001). Conclusions: The IBF is an important descriptor of the PSA kinetics after radiotherapy to identify men at high risk of clinical failure and death. A IBF of <18 months could aid in selecting men for early, aggressive salvage therapy or participation in a clinical trial.

  11. A solvent replenishment solution for managing evaporation of biochemical reactions in air-matrix digital microfluidics devices

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Jebrail, Mais J.; Renzi, Ronald F.; Sinha, Anupama; Van De Vreugde, Jim; Gondhalekar, Carmen; Ambriz, Cesar; Meagher, Robert J.; Branda, Steven S.

    2014-10-01

    Digital microfluidics (DMF) is a powerful technique for sample preparation and analysis for a broad range of biological and chemical applications. In many cases, it is desirable to carry out DMF on an open surface, such that the matrix surrounding the droplets is ambient air. However, the utility of the air-matrix DMF format has been severely limited by problems with droplet evaporation, especially when the droplet-based biochemical reactions require high temperatures for long periods of time. We present a simple solution for managing evaporation in air-matrix DMF: just-in-time replenishment of the reaction volume using droplets of solvent. We demonstrate thatmore »this solution enables DMF-mediated execution of several different biochemical reactions (RNA fragmentation, first-strand cDNA synthesis, and PCR) over a range of temperatures (4–95 °C) and incubation times (up to 1 h or more) without use of oil, humidifying chambers, or off-chip heating modules. Reaction volumes and temperatures were maintained roughly constant over the course of each experiment, such that the reaction kinetics and products generated by the air-matrix DMF device were comparable to those of conventional benchscale reactions. As a result, this simple yet effective solution for evaporation management is an important advance in developing air-matrix DMF for a wide variety of new, high-impact applications, particularly in the biomedical sciences.« less

  12. A solvent replenishment solution for managing evaporation of biochemical reactions in air-matrix digital microfluidics devices

    SciTech Connect (OSTI)

    Jebrail, Mais J.; Renzi, Ronald F.; Sinha, Anupama; Van De Vreugde, Jim; Gondhalekar, Carmen; Ambriz, Cesar; Meagher, Robert J.; Branda, Steven S.

    2014-10-01

    Digital microfluidics (DMF) is a powerful technique for sample preparation and analysis for a broad range of biological and chemical applications. In many cases, it is desirable to carry out DMF on an open surface, such that the matrix surrounding the droplets is ambient air. However, the utility of the air-matrix DMF format has been severely limited by problems with droplet evaporation, especially when the droplet-based biochemical reactions require high temperatures for long periods of time. We present a simple solution for managing evaporation in air-matrix DMF: just-in-time replenishment of the reaction volume using droplets of solvent. We demonstrate that this solution enables DMF-mediated execution of several different biochemical reactions (RNA fragmentation, first-strand cDNA synthesis, and PCR) over a range of temperatures (4–95 °C) and incubation times (up to 1 h or more) without use of oil, humidifying chambers, or off-chip heating modules. Reaction volumes and temperatures were maintained roughly constant over the course of each experiment, such that the reaction kinetics and products generated by the air-matrix DMF device were comparable to those of conventional benchscale reactions. As a result, this simple yet effective solution for evaporation management is an important advance in developing air-matrix DMF for a wide variety of new, high-impact applications, particularly in the biomedical sciences.

  13. IOP PUBLISHING JOURNAL OF OPTICS A: PURE AND APPLIED OPTICS J. Opt. A: Pure Appl. Opt. 9 (2007) S228S234 doi:10.1088/1464-4258/9/8/S16

    E-Print Network [OSTI]

    Walker, Thad G.

    2007-01-01

    IOP PUBLISHING JOURNAL OF OPTICS A: PURE AND APPLIED OPTICS J. Opt. A: Pure Appl. Opt. 9 (2007) S228­S234 doi:10.1088/1464-4258/9/8/S16 Optical forces on particles of arbitrary shape and size Douglas/S228 Abstract In this paper we present a theory of optical forces on particles of arbitrary shape

  14. IOP PUBLISHING JOURNAL OF OPTICS A: PURE AND APPLIED OPTICS J. Opt. A: Pure Appl. Opt. 11 (2009) 094016 (6pp) doi:10.1088/1464-4258/11/9/094016

    E-Print Network [OSTI]

    2009-01-01

    or optical vortices. We show that the energy flows are gradually frozen for slow-light at the Brillouin zone with the formation of local circular and spiral energy flows or optical vortices [9­11]. In general, optical vorticesIOP PUBLISHING JOURNAL OF OPTICS A: PURE AND APPLIED OPTICS J. Opt. A: Pure Appl. Opt. 11 (2009

  15. Impact on biochemical research of the discovery of stable isotopes: the outcome of the serendipic meeting of a refugee with the discoverer of heavy isotopes at Columbia University

    SciTech Connect (OSTI)

    Shemin, D.

    1987-03-01

    As late as the 1930s, approaches to biochemical research not only were rather primitive, but a certain amount of mysticism still surrounded the biochemical events that occur in the living cell. To a great extent, this was due to the lack of techniques needed to uncover the subtle reactions in the living cell. In the early 1930s, an accidental meeting of two scientists revolutionized approaches in biochemical studies and led to the scientific explosion in molecular biology that has occurred during the last few decades. The dark political storm in Germany deposited Dr. Rudolf Schoenheimer on the New York shore, where he met Professor Urey, who recently had discovered ''heavy'' hydrogen. Schoenheimer suggested that biological compounds tagged with heavy atoms of hydrogen would enable investigators to follow their metabolic pathways. This intellectual leap revolutionized the thinking and design of experiments and made it possible to uncover the myriad reactions that occur in the living cell.

  16. Biochemical Response to Androgen Deprivation Therapy Before External Beam Radiation Therapy Predicts Long-term Prostate Cancer Survival Outcomes

    SciTech Connect (OSTI)

    Zelefsky, Michael J.; Gomez, Daniel R.; Polkinghorn, William R.; Pei, Xin; Kollmeier, Marisa

    2013-07-01

    Purpose: To determine whether the response to neoadjuvant androgen deprivation therapy (ADT) defined by a decline in prostate-specific antigen (PSA) to nadir values is associated with improved survival outcomes after external beam radiation therapy (EBRT) for prostate cancer. Methods and Materials: One thousand forty-five patients with localized prostate cancer were treated with definitive EBRT in conjunction with neoadjuvant and concurrent ADT. A 6-month course of ADT was used (3 months during the neoadjuvant phase and 2 to 3 months concurrently with EBRT). The median EBRT prescription dose was 81 Gy using a conformal-based technique. The median follow-up time was 8.5 years. Results: The 10-year PSA relapse-free survival outcome among patients with pre-radiation therapy PSA nadirs of ?0.3 ng/mL was 74.3%, compared with 57.7% for patients with higher PSA nadir values (P<.001). The 10-year distant metastases-free survival outcome among patients with pre-radiation therapy PSA nadirs of ?0.3 ng/mL was 86.1%, compared with 78.6% for patients with higher PSA nadir values (P=.004). In a competing-risk analysis, prostate cancer-related deaths were also significantly reduced among patients with pre-radiation therapy PSA nadirs of <0.3 ng/mL compared with higher values (7.8% compared with 13.7%; P=.009). Multivariable analysis demonstrated that the pre-EBRT PSA nadir value was a significant predictor of long-term biochemical tumor control, distant metastases-free survival, and cause-specific survival outcomes. Conclusions: Pre-radiation therapy nadir PSA values of ?0.3 ng/mL after neoadjuvant ADT were associated with improved long-term biochemical tumor control, reduction in distant metastases, and prostate cancer-related death. Patients with higher nadir values may require alternative adjuvant therapies to improve outcomes.

  17. Apple latent spherical virus vectors for reliable and effective virus-induced gene silencing among a broad range of plants including tobacco, tomato, Arabidopsis thaliana, cucurbits, and legumes

    SciTech Connect (OSTI)

    Igarashi, Aki; Yamagata, Kousuke; Sugai, Tomokazu; Takahashi, Yukari; Sugawara, Emiko; Tamura, Akihiro; Yaegashi, Hajime; Yamagishi, Noriko; Takahashi, Tsubasa; Isogai, Masamichi; Takahashi, Hideki; Yoshikawa, Nobuyuki

    2009-04-10

    Apple latent spherical virus (ALSV) vectors were evaluated for virus-induced gene silencing (VIGS) of endogenous genes among a broad range of plant species. ALSV vectors carrying partial sequences of a subunit of magnesium chelatase (SU) and phytoene desaturase (PDS) genes induced highly uniform knockout phenotypes typical of SU and PDS inhibition on model plants such as tobacco and Arabidopsis thaliana, and economically important crops such as tomato, legume, and cucurbit species. The silencing phenotypes persisted throughout plant growth in these plants. In addition, ALSV vectors could be successfully used to silence a meristem gene, proliferating cell nuclear antigen and disease resistant N gene in tobacco and RCY1 gene in A. thaliana. As ALSV infects most host plants symptomlessly and effectively induces stable VIGS for long periods, the ALSV vector is a valuable tool to determine the functions of interested genes among a broad range of plant species.

  18. Response to “Comment on ‘Twin symmetry texture of energetically condensed niobium thin films on sapphire substrate’ ” [J. Appl. Phys. 112, 016101 (2012)

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Zhao, X.; Philips, L.; Reece, C. E.; Seo, Kang; Krishnan, M.; Valderrama, E.

    2012-07-01

    Welander is correct about the misidentified crystal-directions in the top-view sapphire lattice (Fig. 4 [Zhao et al., J. Appl. Phys. 110, 033523 (2011)]). He is also correct about the misorientation of the pole figures in Fig. 4. In Fig. 1 of this response, we have corrected these errors. Perhaps because of these errors, Welander misconstrued our discussion of the Nbcrystal growth as claiming a new 3D registry. That was not our intention. Rather, we wished to highlight the role of energetic condensation that drives low-defect crystal growth by a combination of non-equilibrium sub-plantation that disturbs the substrate lattice and thermalmore »annealing that annihilates defects and promotes large-grain crystal growth.« less

  19. Biochem. J. (2008) 414, 375381 (Printed in Great Britain) doi:10.1042/BJ20080889 375 Structural and mechanistic insights into type II trypanosomatid

    E-Print Network [OSTI]

    Schnaufer, Achim

    2008-01-01

    conformational change in the secondary- structure architecture, as reported for certain plant GPXs. A modelBiochem. J. (2008) 414, 375­381 (Printed in Great Britain) doi:10.1042/BJ20080889 375 Structural. Despite its similarity to members of the GPX (glutathione peroxidase) family, TbTDPX2 is functional

  20. Congress on Evolutionary Computation 2003, Canberra, 812 Dec 2003, pp807814, IEEE press Predicting Biochemical Interactions Human P450 2D6 Enzyme Inhibition

    E-Print Network [OSTI]

    Fernandez, Thomas

    Predicting Biochemical Interactions ­ Human P450 2D6 Enzyme Inhibition W. B. Langdon Computer Science. Barrett Data Exploration Sciences, GlaxoSmithKline, Research and Development, Greenford, Middlesex, UK B. F. Buxton Computer Science, University College, London. Gower Street, London, WC1E 6BT, UK http

  1. UNCORRECTEDPROOF Please cite this article in press as: Ramos JW, The regulation of extracellular signal-regulated kinase (ERK) in mammalian cells, Int J Biochem Cell

    E-Print Network [OSTI]

    Ramos, Joe W.

    signal-regulated kinase (ERK) in mammalian cells, Int J Biochem Cell Biol (2008), doi:10.1016/j of extracellular signal-regulated kinase (ERK) in mammalian cells 2 3 Joe W. Ramos 2 Department of Natural Products Received in revised form 18 April 20089 Accepted 25 April 200810 Available online xxx11 12 Keywords:13 ERK

  2. Interannual variability of summer biochemical enhancement in relation to mesoscale eddies at the shelf break in the vicinity of the Pribilof Islands,

    E-Print Network [OSTI]

    Interannual variability of summer biochemical enhancement in relation to mesoscale eddies the 1300-km-long eastern shelf break accompanied by a mesoscale eddy field (Okkonen, 2001a). Eddies occur., 2002). Mesoscale eddies, which penetrate to depths of at least 1000 m (Roden, 1995; Mizobata et al

  3. Biochemical failure and the temporal kinetics of prostate-specific antigen after radiation therapy with androgen deprivation

    SciTech Connect (OSTI)

    Buyyounouski, Mark K. [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Hanlon, Alexandra L. [Department of Biostatistics, Fox Chase Cancer Center, Philadelphia, PA (United States); Horwitz, Eric M. [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Uzzo, Robert G. [Department of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Pollack, Alan [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States)]. E-mail: alan.pollack@fccc.edu

    2005-04-01

    Purpose: The accuracy of the American Society of Therapeutic Radiation Oncology consensus definition of biochemical failure (BF) after radiation therapy (RT) and androgen deprivation (AD) has been questioned, because posttreatment prostate-specific antigen (PSA) levels typically rise after release from AD, and misclassification of BF may be made. The temporal kinetics of posttreatment PSA levels was examined to define the error in the classification of BF. Methods and Materials: Between December 1, 1991 and April 30, 1998, 688 men with T1c-T3 NX/0 M0 prostate cancer received three-dimensional conformal RT alone (n = 586) or in combination with either short-term (STAD: 3 to 12 months, n = 82) or long-term (LTAD: 12 to 36 months, n = 20) AD. Follow-up, calculated from the end of all treatment, was {>=}48 months. The mean posttreatment PSA was calculated in 3-month intervals. Results: The median posttreatment clinical follow-up period was 76 months (range, 48-152 months). The posttreatment PSA values from the end of all treatment for the RT+STAD-BF group showed an initial period of rise followed by a period of decline at 30 months and then a continued rise again. The decline in the mean posttreatment PSA is explained in part by stabilization in PSA level after 3 consecutive rises. Nonbiochemical failures (NBF) after RT+STAD had a relatively constant mean PSA over time of approximately 0.5 ng/mL. Unlike the RT+STAD-NBF profile, the RT+LTAD-NBF profile rose continuously and steadily to a level approaching 1 ng/mL. The RT+LTAD-BF profile rose continuously but at a slower rate over time. Nine RT+STAD-NBF patients (22%) and 2 RT+LTAD-BF (29%) patients experienced 3 consecutive rises followed by a subsequent decline and stabilization of PSA compared to 10 RT-BF patients (5%). Redistributing these misclassified patients to their respective NBF groups changed the mean posttreatment PSA profiles as follows: The RT+LTAD-BF profile rose constantly and steadily with a doubling time of approximately 16 months, and the RT+LAD-NF initially rose to a value of approximately 0.5 ng/mL, then at 36 months began to decline. Conclusions: The temporal kinetics of posttreatment PSA after RT+AD and RT alone are different. The American Society of Therapeutic Radiation Oncology definition for biochemical failure overestimates BF in 20-30% after RT+AD compared to 5% after RT alone.

  4. Economic feasibility of biochemical processes for the upgrading of crudes and the removal of sulfur, nitrogen, and trace metals from crude oil -- Benchmark cost establishment of biochemical processes on the basis of conventional downstream technologies. Final report FY95

    SciTech Connect (OSTI)

    Premuzic, E.T.

    1996-08-01

    During the past several years, a considerable amount of work has been carried out showing that microbially enhanced oil recovery (MEOR) is promising and the resulting biotechnology may be deliverable. At Brookhaven National Laboratory (BNL), systematic studies have been conducted which dealt with the effects of thermophilic and thermoadapted bacteria on the chemical and physical properties of selected types of crude oils at elevated temperatures and pressures. Current studies indicate that during the biotreatment several chemical and physical properties of crude oils are affected. The oils are (1) emulsified; (2) acidified; (3) there is a qualitative and quantitative change in light and heavy fractions of the crudes; (4) there are chemical changes in fractions containing sulfur compounds; (5) there is an apparent reduction in the concentration of trace metals; and (6) the qualitative and quantitative changes appear to be microbial species dependent; and (7) there is a distinction between biodegraded and biotreated oils. The downstream biotechnological crude oil processing research performed thus far is of laboratory scale and has focused on demonstrating the technical feasibility of downstream processing with different types of biocatalysts under a variety of processing conditions. Quantitative economic analysis is the topic of the present project which investigates the economic feasibility of the various biochemical downstream processes which hold promise in upgrading of heavy crudes, such as those found in California, e.g., Monterey-type, Midway Sunset, Honda crudes, and others.

  5. Measuring Time to Biochemical Failure in the TROG 96.01 Trial: When Should the Clock Start Ticking?

    SciTech Connect (OSTI)

    Denham, James W.; Steigler, Allison; Kumar, Mahesh; Lamb, David S.; Joseph, David; Spry, Nigel A.; Tai, Keen-Hun; Atkinson, Chris; Turner, Sandra FRANZCR; Greer, Peter B.; Gleeson, Paul S.; D'Este, Catherine

    2009-11-15

    Purpose: We sought to determine whether short-term neoadjuvant androgen deprivation (STAD) duration influences the optimal time point from which Phoenix fail (time to biochemical failure; TTBF) should be measured. Methods and Materials: In the Trans-Tasman Radiation Oncology Group 96.01 trial, men with locally advanced prostate cancer were randomized to 3 or 6 months STAD before and during prostatic irradiation (XRT) or to XRT alone. The prognostic value of TTBF measured from the end of radiation (ERT) and randomization were compared using Cox models. Results: Between 1996 and 2000, 802 eligible patients were randomized. In 436 men with Phoenix failure, TTBF measured from randomization was a powerful predictor of prostate cancer-specific survival and marginally more accurate than TTBF measured from ERT in Cox models. Insufficient data were available to confirm that TTBF measured from testosterone recovery may also be a suitable option. Conclusions: TTBF measured from randomization (commencement of therapy) performed well in this trial dataset and will be a convenient option if this finding holds in other datasets that include long-term androgen deprivation data.

  6. Chemical and Structural Features of Plants That Contribute to Biomass Recalcitrance

    E-Print Network [OSTI]

    DeMartini, Jaclyn Diana

    2011-01-01

    Wheat Straw Pretreated for Bioethanol Production. BiotechnolWheat Straw Pretreated for Bioethanol Production. Biotechnol1996) Handbook on Bioethanol: Production and Utilization (

  7. Metabolic engineering of microorganisms for biofuels production: from bugs to synthetic biology to fuels

    E-Print Network [OSTI]

    Kuk Lee, Sung

    2010-01-01

    of microbial hosts for biofuels production. Metab Eng 2008,delivers next-generation biofuels. Nat Biotechnol 27.furfural (HMF). Biotechnol Biofuels 2008, 1:12. 40. Trinh

  8. Chemical and Structural Features of Plants That Contribute to Biomass Recalcitrance

    E-Print Network [OSTI]

    DeMartini, Jaclyn Diana

    2011-01-01

    Straw Pretreated for Bioethanol Production. Biotechnol forStraw Pretreated for Bioethanol Production. Biotechnol for1996) Handbook on Bioethanol: Production and Utilization (

  9. Microfluidic Technology Platforms for Synthesizing, Labeling and Measuring the Kinetics of Transport and Biochemical Reactions for Developing Molecular Imaging Probes

    SciTech Connect (OSTI)

    Phelps, Michael E.

    2009-09-01

    Radiotracer techniques are used in environmental sciences, geology, biology and medicine. Radiotracers with Positron Emission Tomography (PET) provided biological examinations of ~3 million patients 2008. Despite the success of positron labeled tracers in many sciences, there is limited access in an affordable and convenient manner to develop and use new tracers. Integrated microfluidic chips are a new technology well matched to the concentrations of tracers. Our goal is to develop microfluidic chips and new synthesis approaches to enable wide dissemination of diverse types of tracers at low cost, and to produce new generations of radiochemists for which there are many unfilled jobs. The program objectives are to: 1. Develop an integrated microfluidic platform technology for synthesizing and 18F-labeling diverse arrays of different classes of molecules. 2. Incorporate microfluidic chips into small PC controlled devices (“Synthesizer”) with a platform interfaced to PC for electronic and fluid input/out control. 3. Establish a de-centralized model with Synthesizers for discovering and producing molecular imaging probes, only requiring delivery of inexpensive [18F]fluoride ion from commercial PET radiopharmacies vs the centralized approach of cyclotron facilities synthesizing and shipping a few different types of 18F-probes. 4. Develop a position sensitive avalanche photo diode (PSAPD) camera for beta particles embedded in a microfluidic chip for imaging and measuring transport and biochemical reaction rates to valid new 18F-labeled probes in an array of cell cultures. These objectives are met within a research and educational program integrating radio-chemistry, synthetic chemistry, biochemistry, engineering and biology in the Crump Institute for Molecular Imaging. The Radiochemistry Training Program exposes PhD and post doctoral students to molecular imaging in vitro in cells and microorganisms in microfluidic chips and in vivo with PET, from new technologies for radiochemistry (macro to micro levels), biochemistry and biology to imaging principles, tracer kinetics, pharmacokinetics and biochemical assays. New generations of radiochemists will be immersed in the biochemistry and biology for which their labeled probes are being developed for assays of these processes. In this program engineers and radio-chemists integrate the principles of microfluidics and radiolabeling along with proper system design and chemistry rule sets to yield Synthesizers enabling biological and pharmaceutical scientists to develop diverse arrays of probes to pursue their interests. This progression would allow also radiochemists to focus on the further evolution of rapid, high yield synthetic reactions with new enabling technologies, rather than everyday production of radiotracers that should be done by technologists. The invention of integrated circuits in electronics established a platform technology that allowed an evolution of ideas and applications far beyond what could have been imagined at the beginning. Rather than provide a technology for the solution to a single problem, it is hoped that microfluidic radiochemistry will be an enabling platform technology for others to solve many problems. As part of this objective, another program goal is to commercialize the technologies that come from this work so that they can be provided to others who wish to use it.

  10. Thomas Vigdal Biochem 218

    E-Print Network [OSTI]

    in this paper include B-DNA twist (Gorin et al., 1995), A-philicity (Ivanov and Minchenkova, 1995; Lu et al., 2000), DNA bending (Brukner et al., 1995) and protein-induced deformability (Olson et al., 1998). B within the DNA helix. Along with A-philicity, DNA bending can lead to changes in the width and depths

  11. Sara Kaiser Biochem 118

    E-Print Network [OSTI]

    Brutlag, Doug

    , or abdominal pain; in the chest, shortness of breath or cough may develop. If the brain is involved, patients

  12. Multiple capillary biochemical analyzer

    DOE Patents [OSTI]

    Dovichi, Norman J. (Edmonton, CA); Zhang, Jian Z. (Edmonton, CA)

    1995-01-01

    A multiple capillary analyzer allows detection of light from multiple capillaries with a reduced number of interfaces through which light must pass in detecting light emitted from a sample being analyzed, using a modified sheath flow cuvette. A linear or rectangular array of capillaries is introduced into a rectangular flow chamber. Sheath fluid draws individual sample streams through the cuvette. The capillaries are closely and evenly spaced and held by a transparent retainer in a fixed position in relation to an optical detection system. Collimated sample excitation radiation is applied simultaneously across the ends of the capillaries in the retainer. Light emitted from the excited sample is detected by the optical detection system. The retainer is provided by a transparent chamber having inward slanting end walls. The capillaries are wedged into the chamber. One sideways dimension of the chamber is equal to the diameter of the capillaries and one end to end dimension varies from, at the top of the chamber, slightly greater than the sum of the diameters of the capillaries to, at the bottom of the chamber, slightly smaller than the sum of the diameters of the capillaries. The optical system utilizes optic fibres to deliver light to individual photodetectors, one for each capillary tube. A filter or wavelength division demultiplexer may be used for isolating fluorescence at particular bands.

  13. Multiple capillary biochemical analyzer

    DOE Patents [OSTI]

    Dovichi, N.J.; Zhang, J.Z.

    1995-08-08

    A multiple capillary analyzer allows detection of light from multiple capillaries with a reduced number of interfaces through which light must pass in detecting light emitted from a sample being analyzed, using a modified sheath flow cuvette. A linear or rectangular array of capillaries is introduced into a rectangular flow chamber. Sheath fluid draws individual sample streams through the cuvette. The capillaries are closely and evenly spaced and held by a transparent retainer in a fixed position in relation to an optical detection system. Collimated sample excitation radiation is applied simultaneously across the ends of the capillaries in the retainer. Light emitted from the excited sample is detected by the optical detection system. The retainer is provided by a transparent chamber having inward slanting end walls. The capillaries are wedged into the chamber. One sideways dimension of the chamber is equal to the diameter of the capillaries and one end to end dimension varies from, at the top of the chamber, slightly greater than the sum of the diameters of the capillaries to, at the bottom of the chamber, slightly smaller than the sum of the diameters of the capillaries. The optical system utilizes optic fibers to deliver light to individual photodetectors, one for each capillary tube. A filter or wavelength division demultiplexer may be used for isolating fluorescence at particular bands. 21 figs.

  14. Percentage of Biopsy Cores Positive for Malignancy and Biochemical Failure Following Prostate Cancer Radiotherapy in 3,264 Men: Statistical Significance Without Predictive Performance

    SciTech Connect (OSTI)

    Williams, Scott G. [Peter MacCallum Cancer Centre and University of Melbourne, Melbourne (Australia)], E-mail: scott.williams@petermac.org; Buyyounouski, Mark K. [Fox Chase Cancer Center, Philadelphia, PA (United States); Pickles, Tom [British Columbia Cancer Agency, Vancouver, BC (Canada); Kestin, Larry; Martinez, Alvaro [William Beaumont Hospital, Royal Oak, MI (United States); Hanlon, Alexandra L. [Fox Chase Cancer Center, Philadelphia, PA (United States); Duchesne, Gillian M. [Peter MacCallum Cancer Centre and University of Melbourne, Melbourne (Australia)

    2008-03-15

    Purpose: To define and incorporate the impact of the percentage of positive biopsy cores (PPC) into a predictive model of prostate cancer radiotherapy biochemical outcome. Methods and Materials: The data of 3264 men with clinically localized prostate cancer treated with external beam radiotherapy at four institutions were retrospectively analyzed. Standard prognostic and treatment factors plus the number of biopsy cores collected and the number positive for malignancy by transrectal ultrasound-guided biopsy were available. The primary endpoint was biochemical failure (bF, Phoenix definition). Multivariate proportional hazards analyses were performed and expressed as a nomogram and the model's predictive ability assessed using the concordance index (c-index). Results: The cohort consisted of 21% low-, 51% intermediate-, and 28% high-risk cancer patients, and 30% had androgen deprivation with radiotherapy. The median PPC was 50% (interquartile range [IQR] 29-67%), and median follow-up was 51 months (IQR 29-71 months). Percentage of positive biopsy cores displayed an independent association with the risk of bF (p = 0.01), as did age, prostate-specific antigen value, Gleason score, clinical stage, androgen deprivation duration, and radiotherapy dose (p < 0.001 for all). Including PPC increased the c-index from 0.72 to 0.73 in the overall model. The influence of PPC varied significantly with radiotherapy dose and clinical stage (p = 0.02 for both interactions), with doses <66 Gy and palpable tumors showing the strongest relationship between PPC and bF. Intermediate-risk patients were poorly discriminated regardless of PPC inclusion (c-index 0.65 for both models). Conclusions: Outcome models incorporating PPC show only minor additional ability to predict biochemical failure beyond those containing standard prognostic factors.

  15. Biologically Effective Dose (BED) Correlation With Biochemical Control After Low-Dose Rate Prostate Brachytherapy for Clinically Low-Risk Prostate Cancer

    SciTech Connect (OSTI)

    Miles, Edward F.; Nelson, John W.; Alkaissi, Ali K.; Das, Shiva; Clough, Robert W.; Broadwater, Gloria; Anscher, Mitchell S.; Chino, Junzo P.; Oleson, James R.

    2010-05-01

    Purpose: To assess the correlation of postimplant dosimetric quantifiers with biochemical control of prostate cancer after low-dose rate brachytherapy. Methods and Materials: The biologically effective dose (BED), dose in Gray (Gy) to 90% of prostate (D{sub 90}), and percent volume of the prostate receiving 100% of the prescription dose (V{sub 100}) were calculated from the postimplant dose-volume histogram for 140 patients undergoing low-dose rate prostate brachytherapy from 1997 to 2003 at Durham Regional Hospital and the Durham VA Medical Center (Durham, NC). Results: The median follow-up was 50 months. There was a 7% biochemical failure rate (10 of 140), and 91% of patients (127 of 140) were alive at last clinical follow-up. The median BED was 148 Gy (range, 46-218 Gy). The median D{sub 90} was 139 Gy (range, 45-203 Gy). The median V{sub 100} was 85% (range, 44-100%). The overall 5-year biochemical relapse-free survival (bRFS) rate was 90.1%. On univariate Cox proportional hazards modeling, no pretreatment characteristic (Gleason score sum, age, baseline prostate-specific antigen, or clinical stage) was predictive of bRFS. The BED, D{sub 90}, and V{sub 100} were all highly correlated (Pearson coefficients >92%), and all were strongly correlated with bRFS. Using the Youden method, we identified the following cut points for predicting freedom from biochemical failure: D{sub 90} >= 110 Gy, V{sub 100} >= 74%, and BED >= 115 Gy. None of the covariates significantly predicted overall survival. Conclusions: We observed significant correlation between BED, D{sub 90}, and V{sub 100} with bRFS. The BED is at least as predictive of bRFS as D{sub 90} or V{sub 100}. Dosimetric quantifiers that account for heterogeneity in tumor location and dose distribution, tumor repopulation, and survival probability of tumor clonogens should be investigated.

  16. PSA Bounce and Biochemical Failure After Brachytherapy for Prostate Cancer: A Study of 820 Patients With a Minimum of 3 Years of Follow-Up

    SciTech Connect (OSTI)

    Caloglu, Murat, E-mail: caloglumurat@hotmail.com [Department of Radiation Oncology, Faculty of Medicine, Trakya University, Edirne (Turkey); Ciezki, Jay P.; Reddy, Chandana A. [Department of Radiation Oncology, Cleveland Clinic, Cleveland, OH (United States); Angermeier, Kenneth; Ulchaker, James [Glickman Urologic Institute, Cleveland Clinic, Cleveland, OH (United States); Chehade, Nabil; Altman, Andrew [Department of Urology, Kaiser Permanente-Ohio, Parma, OH (United States); Magi-Galuzzi, Christina [Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH (United States); Klein, Eric A. [Glickman Urologic Institute, Cleveland Clinic, Cleveland, OH (United States)

    2011-07-01

    Purpose: To determine clinical or dosimetric factors associated with a prostate-specific antigen (PSA) bounce, as well as an association between a PSA bounce and biochemical relapse-free survival (bRFS), in patients treated with iodine-125 brachytherapy. Methods and Materials: A variety of clinical and treatment factors were examined in 820 patients who had a minimum of 3 years of PSA follow-up with T1-T2cN0M0 prostate cancer. Four different PSA threshold values were used for defining a PSA bounce: a PSA rise of {>=}0.2, {>=}0.4, {>=}0.6, and {>=}0.8 ng/mL. Results: A PSA bounce of {>=}0.2, {>=}0.4, {>=}0.6, and {>=}0.8 ng/mL was noted in 247 patients (30.1%), 161 (19.6%), 105 (12.8%), and 78 (9.5%), respectively. The median time to the first PSA rise was 17.4, 16.25, 16.23, and 15.71 months, respectively, vs. 34.35 months for a biochemical failure (p < 0.0001). A PSA rise of {>=}0.2 ng/mL was the only definition for which there was a significant difference in bRFS between bounce and non-bounce patients. The 5-year bRFS rate of patients having a PSA bounce of {>=}0.2 was 97.7% vs. 91% for those who did not have a PSA bounce (p = 0.0011). On univariate analysis for biochemical failure, age, risk group, and PSAs per year had a statistically significant correlation with PSA bounce of {>=}0.2 ng/mL. On multivariate analysis, age and PSAs per year remained statistically significant (p < 0.0001 and p = 0.0456, respectively). Conclusions: A bounce definition of a rise {>=}0.2 ng/mL is a reliable definition among several other definitions. The time to first PSA rise is the most valuable factor for distinguishing between a bounce and biochemical failure.

  17. Modeling the Physical and Biochemical Influence of Ocean Thermal Energy Conversion Plant Discharges into their Adjacent Waters

    SciTech Connect (OSTI)

    PAT GRANDELLI, P.E.; GREG ROCHELEAU; JOHN HAMRICK, Ph.D.; MATT CHURCH, Ph.D.; BRIAN POWELL, Ph.D.

    2012-09-29

    This paper describes the modeling work by Makai Ocean Engineering, Inc. to simulate the biochemical effects of of the nutrient-enhanced seawater plumes that are discharged by one or several 100 megawatt OTEC plants. The modeling is needed to properly design OTEC plants that can operate sustainably with acceptably low biological impact. In order to quantify the effect of discharge configuration and phytoplankton response, Makai Ocean Engineering implemented a biological and physical model for the waters surrounding O`ahu, Hawai`i, using the EPA-approved Environmental Fluid Dynamics Code (EFDC). Each EFDC grid cell was approximately 1 square kilometer by 20 meters deep, and used a time step of three hours. The biological model was set up to simulate the biochemical response for three classes of organisms: Picoplankton (< 2 um) such as prochlorococccus, nanoplankton (2-20 um), and microplankton (> 20 um) e.g., diatoms. The dynamic biological phytoplankton model was calibrated using chemical and biological data collected for the Hawaii Ocean Time Series (HOTS) project. Peer review of the biological modeling was performed. The physical oceanography model uses boundary conditions from a surrounding Hawai'i Regional Ocean Model, (ROM) operated by the University of Hawai`i and the National Atmospheric and Oceanic Administration. The ROM provided tides, basin scale circulation, mesoscale variability, and atmospheric forcing into the edges of the EFDC computational domain. This model is the most accurate and sophisticated Hawai'ian Regional Ocean Model presently available, assimilating real-time oceanographic observations, as well as model calibration based upon temperature, current and salinity data collected during 2010 near the simulated OTEC site. The ROM program manager peer-reviewed Makai's implementation of the ROM output into our EFDC model. The supporting oceanographic data was collected for a Naval Facilities Engineering Command / Makai project. Results: The model was run for a 100 MW OTEC Plant consisting of four separate ducts, discharging a total combined flow rate of 420 m3/s of warm water and 320 m3/s of cold water in a mixed discharge at 70 meters deep. Each duct was assumed to have a discharge port diameter of 10.5m producing a downward discharge velocity of about 2.18 m/s. The natural system, as measured in the HOTS program, has an average concentration of 10-15 mgC/m3. To calibrate the biological model, we first ran the model with no OTEC plant and varied biological parameters until the simulated data was a good match to the HOTS observations. This modeling showed that phytoplankton concentration were patchy and highly dynamic. The patchiness was a good match with the data variability observed within the HOTS data sets. We then ran the model with simulated OTEC intake and discharge flows and associated nutrients. Directly under the OTEC plant, the near-field plume has an average terminal depth of 172 meters, with a volumetric dilution of 13:1. The average terminal plume temperature was 19.8oC. Nitrate concentrations are 1 to 2 umol/kg above ambient. The advecting plume then further dilutes to less than 1 umol/kg above ambient within a few kilometers downstream, while remaining at depth. Because this terminal near-field plume is well below the 1% light limited depths (~120m), no immediate biological utilization of the nutrients occurs. As the nitrate is advected and dispersed downstream, a fraction of the deep ocean nutrients (< 0.5 umol/kg perturbation) mix upward where they are utilized by the ambient phytoplankton population. This occurs approximately twenty-five kilometers downstream from the plant at 110 - 70 meters depth. For pico-phytoplankton, modeling results indicate that this nutrient perturbation causes a phytoplankton perturbation of approximately 1 mgC/m3 (~10% of average ambient concentrations) that covers an area 10x5 km in size at the 70 to 90m depth. Thus, the perturbations are well within the natural variability of the system, generally corresponding to a 10 to 15% increase above the a

  18. Tomko and Dunlop Biotechnol Biofuels (2015) 8:165 DOI 10.1186/s13068-015-0347-3

    E-Print Network [OSTI]

    Dunlop, Mary

    2015-01-01

    -jet fuels, however these fuels are often toxic to cells, limiting production yields. There are natural exam, such as those that thrive near natural oil seeps and in oil-polluted waters. Results: Using genomic DNA from production. There are many natural examples of microor- ganisms that survive in hydrocarbon-rich environments

  19. J. Microbiol. Biotechnol. (2007), 17(11), 18751879 Arthrobacter subterraneus sp. nov., Isolated from Deep Subsurface Water of

    E-Print Network [OSTI]

    Bae, Jin-Woo

    2007-01-01

    from Deep Subsurface Water of the South Coast of Korea CHANG,HO-WON1,2 ,JIN-WOOBAE1 ,YOUNG-DONAM1 ,HYUK-yellow pigmented bacterial strain CH7T was isolated using a dilution-plating technique from deep subsurface water, Chungnam National University, Daejeon 306-764, Korea3 Department of Microbiology and Microbial Engineering

  20. J Ind Microbiol Biotechnol (2011) 38:873890 DOI 10.1007/s10295-011-0970-3

    E-Print Network [OSTI]

    Zhao, Huimin

    2011-01-01

    the formation of byproducts. Third, some com- pounds with complex structures already have natural syn- thetic, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA H. Zhao (&) Departments of Chemistry and Biochemistry, Institute of Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA e

  1. 4. Gilbert, L. A. et al. Cell 154, 442451 (2013). 5. Mali, P. et al. Nature Biotechnol. 31, 833838

    E-Print Network [OSTI]

    Risbey, James S.

    2013-01-01

    variations3 . The 1995 Intergovernmental Panel on Climate Change report4 identi- fied volcanic activity, variations in incoming solar radiation, and ocean circulation as drivers of decadal and longer variability in global surface temperature. An innovation of Marotzke and Forster's work is their use of coupled ocean

  2. J Ind Microbiol Biotechnol (2015) 42:437451 DOI 10.1007/s10295-014-1518-0

    E-Print Network [OSTI]

    Zhao, Huimin

    2015-01-01

    , Biochemistry, and Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA #12;438 J

  3. J. Microbiol. Biotechnol. (2006), 16(2), 232239 Bacterial Community Structure in Activated Sludge Reactors Treating Free

    E-Print Network [OSTI]

    Bae, Jin-Woo

    2006-01-01

    of cyanide, current water pollution control laws in most countries require the complete removal of cyanide treatments. Lately, scientific investigation of the biological treatment of cyanide-containing wastewater as an alternative to chemical processes is being increasingly undertaken. Biological treatment of cyanide

  4. Process Design and Economics for Biochemical Conversion of Lignocellulosic Biomass to Ethanol: Dilute-Acid Pretreatment and Enzymatic Hydrolysis of Corn Stover

    SciTech Connect (OSTI)

    Humbird, D.; Davis, R.; Tao, L.; Kinchin, C.; Hsu, D.; Aden, A.; Schoen, P.; Lukas, J.; Olthof, B.; Worley, M.; Sexton, D.; Dudgeon, D.

    2011-03-01

    This report describes one potential biochemical ethanol conversion process, conceptually based upon core conversion and process integration research at NREL. The overarching process design converts corn stover to ethanol by dilute-acid pretreatment, enzymatic saccharification, and co-fermentation. Building on design reports published in 2002 and 1999, NREL, together with the subcontractor Harris Group Inc., performed a complete review of the process design and economic model for the biomass-to-ethanol process. This update reflects NREL's current vision of the biochemical ethanol process and includes the latest research in the conversion areas (pretreatment, conditioning, saccharification, and fermentation), optimizations in product recovery, and our latest understanding of the ethanol plant's back end (wastewater and utilities). The conceptual design presented here reports ethanol production economics as determined by 2012 conversion targets and 'nth-plant' project costs and financing. For the biorefinery described here, processing 2,205 dry ton/day at 76% theoretical ethanol yield (79 gal/dry ton), the ethanol selling price is $2.15/gal in 2007$.

  5. Please cite this article in press as: M. Suchea, et al., Nanostructured composite layers for electromagnetic shielding in the GHz frequency range, Appl. Surf. Sci. (2015), http://dx.doi.org/10.1016/j.apsusc.2015.01.074

    E-Print Network [OSTI]

    2015-01-01

    for electromagnetic shielding in the GHz frequency range, Appl. Surf. Sci. (2015), http://dx.doi.org/10.1016/j.elsevier.com/locate/apsusc Nanostructured composite layers for electromagnetic shielding in the GHz frequency range M. Sucheaa,b , I-like nanocomposites Graphene nanoplatelets Electromagnetic shielding a b s t r a c t We report on preliminary results

  6. Bio-crude transcriptomics: Gene discovery and metabolic network reconstruction for the biosynthesis of the terpenome of the hydrocarbon oil-producing green alga, Botryococcus braunii race B (Showa)*

    E-Print Network [OSTI]

    2012-01-01

    from microalgae beats bioethanol. Trends Biotechnol 4. Scotta renewable source for bioethanol. Bioresour Technol 2011,

  7. Isochorismate Synthase Enzymes in Arabidopsis

    E-Print Network [OSTI]

    Strawn, Marcus Antoninus

    2010-01-01

    interactions with secondary plant metabolites. 2nd ed. 1991,production of plant secondary metabolites. Biotechnol Adv,

  8. Rapid label-free DNA analysis in picoliter microfluidic droplets using FRET probes

    E-Print Network [OSTI]

    Hsieh, Albert Tsung-Hsi; Pan, Patrick Jen-Hao; Lee, Abraham Phillip

    2009-01-01

    chemistry and life sciences, Boston Jares- Erijman EA, Jovin TM (2003) FRET imaging. Nat Biotechnol Jobs

  9. Upfront Androgen Deprivation Therapy With Salvage Radiation May Improve Biochemical Outcomes in Prostate Cancer Patients With Post-Prostatectomy Rising PSA

    SciTech Connect (OSTI)

    Jang, Joanne W.; Hwang, Wei-Ting; Guzzo, Thomas J.; Wein, Alan J.; Haas, Naomi B.; Both, Stefan; Vapiwala, Neha

    2012-08-01

    Purpose: The addition of androgen deprivation therapy (ADT) to definitive external beam radiation therapy (RT) improves outcomes in higher-risk prostate cancer patients. However, the benefit of ADT with salvage RT in post-prostatectomy patients is not clearly established. Our study compares biochemical outcomes in post-prostatectomy patients who received salvage RT with or without concurrent ADT. Methods and Materials: Of nearly 2,000 post-prostatectomy patients, we reviewed the medical records of 191 patients who received salvage RT at University of Pennsylvania between 1987 and 2007. Follow-up data were obtained by chart review and electronic polling of the institutional laboratory database and Social Security Death Index. Biochemical failure after salvage RT was defined as a prostate-specific antigen of 2.0 ng/mL above the post-RT nadir or the initiation of ADT after completion of salvage RT. Results: One hundred twenty-nine patients received salvage RT alone, and 62 patients received combined ADT and salvage RT. Median follow-up was 5.4 years. Patients who received combined ADT and salvage RT were younger, had higher pathologic Gleason scores, and higher rates of seminal vesicle invasion, lymph node involvement, and pelvic nodal irradiation compared with patients who received salvage RT alone. Patients who received combined therapy had improved biochemical progression-free survival (bPFS) compared with patients who received RT alone (p = 0.048). For patients with pathologic Gleason scores {<=}7, combined RT and ADT resulted in significantly improved bPFS compared to RT alone (p = 0.013). Conclusions: These results suggest that initiating ADT during salvage RT in the post-prostatectomy setting may improve bPFS compared with salvage RT alone. However, prospective randomized data are necessary to definitively determine whether hormonal manipulation should be used with salvage RT. Furthermore, the optimal nature and duration of ADT and the patient subgroups in which ADT could provide the most benefit remain open questions.

  10. Is Biochemical Response More Important Than Duration of Neoadjuvant Hormone Therapy Before Radiotherapy for Clinically Localized Prostate Cancer? An Analysis of the 3- Versus 8-Month Randomized Trial

    SciTech Connect (OSTI)

    Alexander, Abraham, E-mail: aalexander3@bccancer.bc.c [Radiation Therapy Program, British Columbia Cancer Agency, Vancouver Island Centre, University of British Columbia, Victoria, BC (Canada); Crook, Juanita [Department of Radiation Oncology, Princess Margaret Hospital, Toronto, ON (Canada); Jones, Stuart [Radiation Therapy Program, British Columbia Cancer Agency, Vancouver Island Centre, University of British Columbia, Victoria, BC (Canada); Malone, Shawn [Department of Radiation Oncology, Ottawa Regional Cancer Center, Ottawa, ON (Canada); Bowen, Julie [Department of Radiation Oncology, Northeastern Ontario Regional Cancer Center, Sudbury, ON (Canada); Truong, Pauline; Pai, Howard; Ludgate, Charles [Radiation Therapy Program, British Columbia Cancer Agency, Vancouver Island Centre, University of British Columbia, Victoria, BC (Canada)

    2010-01-15

    Purpose: To ascertain whether biochemical response to neoadjuvant androgen-deprivation therapy (ADT) before radiotherapy (RT), rather than duration, is the critical determinant of benefit in the multimodal treatment of localized prostate cancer, by comparing outcomes of subjects from the Canadian multicenter 3- vs 8-month trial with a pre-RT, post-hormone PSA (PRPH-PSA) <=0.1 ng/ml vs those >0.1 ng/ml. Methods and Materials: From 1995 to 2001, 378 men with localized prostate cancer were randomized to 3 or 8 months of neoadjuvant ADT before RT. On univariate analysis, survival indices were compared between those with a PRPH-PSA <=0.1 ng/ml vs >0.1 ng/ml, for all patients and subgroups, including treatment arm, risk group, and gleason Score. Multivariate analysis identified independent predictors of outcome. Results: Biochemical disease-free survival (bDFS) was significantly higher for those with a PRPH-PSA <=0.1 ng/ml compared with PRPH-PSA >0.1 ng/ml (55.3% vs 49.4%, p = 0.014). No difference in survival indices was observed between treatment arms. There was no difference in bDFS between patients in the 3- and 8-month arms with a PRPH-PSA <=0.1 ng/ml nor those with PRPH-PSA >0.1 ng/ml. bDFS was significantly higher for high-risk patients with PRPH-PSA <=0.1 ng/ml compared with PRPH-PSA >0.1 ng/ml (57.0% vs 29.4%, p = 0.017). Multivariate analysis identified PRPH-PSA (p = 0.041), Gleason score (p = 0.001), initial PSA (p = 0.025), and T-stage (p = 0.003), not ADT duration, as independent predictors of outcome. Conclusion: Biochemical response to neoadjuvant ADT before RT, not duration, appears to be the critical determinant of benefit in the setting of combined therapy. Individually tailored ADT duration based on PRPH-PSA would maximize therapeutic gain, while minimizing the duration of ADT and its related toxicities.

  11. Intracellular Mechanisms of Adult Neural Progenitor Proliferation and Self-Renewal

    E-Print Network [OSTI]

    Peltier, Joseph Charles

    2010-01-01

    Appl Biochem 40:5-16. 44. Peltier J, Schaffer DV. (2010).death. Nature 411:42-43. 49. Peltier J, O'Neill A, Schafferaccepted for publication as Peltier J, O’Neill A, Schaffer

  12. appl_household2001.pdf

    Gasoline and Diesel Fuel Update (EIA)

    Appliances Tables (Million U.S. Households; 60 pages, 240 kb) Contents Pages HC5-1a. Appliances by Climate Zone, Million U.S. Households, 2001 5 HC5-2a. Appliances by Year of...

  13. METEOROLOGICAL APPLICATIONS Meteorol. Appl. (2010)

    E-Print Network [OSTI]

    Reading, University of

    2010-01-01

    precipitation returns, requires further development as clutter contamination remained one of the largest error allows insects to be car- ried at much faster speeds than can be achieved close to ground level

  14. Cynthia Sandberg: Love Apple Farm

    E-Print Network [OSTI]

    Rabkin, Sarah

    2010-01-01

    That manure goes into the compost piles. That decomposes,classes and beekeeping and compost and vermiculture. So weor can I produce enough compost and worm castings here so

  15. appl_household2001.pdf

    U.S. Energy Information Administration (EIA) Indexed Site

    18.1 2.0 5.3 4.1 3.3 3.5 9.9 Most-Used Refrigerator Defrost Method Frost-Free ... 96.9 8.0 25.7 21.8 19.1 22.3 7.8 Manual...

  16. appl_household2001.pdf

    Gasoline and Diesel Fuel Update (EIA)

    2001 Appliance Types and Characteristics RSE Column Factor: Total U.S. Four Most Populated States RSE Row Factors New York California Texas Florida 0.4 1.2 1.1 1.4 1.3 Total...

  17. appl_household2001.pdf

    U.S. Energy Information Administration (EIA) Indexed Site

    8a. Appliances by UrbanRural Location, Million U.S. Households, 2001 Appliance Types and Characteristics RSE Column Factor: Total UrbanRural Location 1 RSE Row Factors City Town...

  18. appl_household2001.pdf

    U.S. Energy Information Administration (EIA) Indexed Site

    2a. Appliances by Year of Construction, Million U.S. Households, 2001 Appliance Types and Characteristics RSE Column Factor: Total Year of Construction RSE Row Factors 1990 to 2001...

  19. appl_household2001.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    0a. Appliances by Midwest Census Region, Million U.S. Households, 2001 Appliance Types and Characteristics RSE Column Factor: Total U.S. Midwest Census Region RSE Row Factors Total...

  20. appl_household2001.pdf

    Gasoline and Diesel Fuel Update (EIA)

    5a. Appliances by Type of Owner-Occupied Housing Unit, Million U.S. Households, 2001 Appliance Types and Characteristics RSE Column Factor: Total Owner- Occupied Units Type of...

  1. appl_household2001.pdf

    U.S. Energy Information Administration (EIA) Indexed Site

    1a. Appliances by South Census Region, Million U.S. Households, 2001 Appliance Types and Characteristics RSE Column Factor: Total U.S. South Census Region RSE Row Factors Total...

  2. appl_household2001.pdf

    U.S. Energy Information Administration (EIA) Indexed Site

    9a. Appliances by Northeast Census Region, Million U.S. Households, 2001 Appliance Types and Characteristics RSE Column Factor: Total U.S. Northeast Census Region RSE Row Factors...

  3. appl_household2001.pdf

    U.S. Energy Information Administration (EIA) Indexed Site

    3a. Appliances by Household Income, Million U.S. Households, 2001 Appliance Types and Characteristics RSE Column Factor: Total 2001 Household Income Below Poverty Line Eli- gible...

  4. appl_household2001.pdf

    Gasoline and Diesel Fuel Update (EIA)

    4a. Appliances by Type of Housing Unit, Million U.S. Households, 2001 Appliance Types and Characteristics RSE Column Factor: Total Type of Housing Unit RSE Row Factors...

  5. appl_household2001.pdf

    U.S. Energy Information Administration (EIA) Indexed Site

    6a. Appliances by Type of Rented Housing Unit, Million U.S. Households, 2001 Appliance Types and Characteristics RSE Column Factor: Total Rented Units Type of Rented Housing Unit...

  6. appl_household2001.pdf

    Gasoline and Diesel Fuel Update (EIA)

    2a. Appliances by West Census Region, Million U.S. Households, 2001 Appliance Types and Characteristics RSE Column Factor: Total U.S. West Census Region RSE Row Factors Total...

  7. Cynthia Sandberg: Love Apple Farm

    E-Print Network [OSTI]

    Rabkin, Sarah

    2010-01-01

    I started investigating worm castings and their benefits. [testing on benefits of worm casting tea. So now I’m big onenough compost and worm castings here so that I don’t have

  8. Cynthia Sandberg: Love Apple Farm

    E-Print Network [OSTI]

    Rabkin, Sarah

    2010-01-01

    on benefits of worm casting tea. So now I’m big on feedingWe’ll fertilize crops with worm casting tea that wemake, or compost tea, sometimes both. Every time we plant a

  9. Cynthia Sandberg: Love Apple Farm

    E-Print Network [OSTI]

    Rabkin, Sarah

    2010-01-01

    restaurant in nearby Los Gatos (Santa Clara County), Lovea local restaurant by the name of Manresa in Los Gatos. 3Manresa Restaurant in Los Gatos Rabkin: Let’s talk about

  10. appl_household2001.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorkingLos Alamos verifiesValidation of MFRSR

  11. appl_household2001.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorkingLos Alamos verifiesValidation of MFRSR0a. Appliances by Midwest Census

  12. appl_household2001.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorkingLos Alamos verifiesValidation of MFRSR0a. Appliances by Midwest

  13. appl_household2001.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorkingLos Alamos verifiesValidation of MFRSR0a. Appliances by Midwest2a.

  14. appl_household2001.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorkingLos Alamos verifiesValidation of MFRSR0a. Appliances by Midwest2a.a.

  15. appl_household2001.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorkingLos Alamos verifiesValidation of MFRSR0a. Appliances by Midwest2a.a.2a.

  16. appl_household2001.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorkingLos Alamos verifiesValidation of MFRSR0a. Appliances by

  17. appl_household2001.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorkingLos Alamos verifiesValidation of MFRSR0a. Appliances by4a. Appliances

  18. appl_household2001.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorkingLos Alamos verifiesValidation of MFRSR0a. Appliances by4a.

  19. appl_household2001.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorkingLos Alamos verifiesValidation of MFRSR0a. Appliances by4a.6a.

  20. appl_household2001.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorkingLos Alamos verifiesValidation of MFRSR0a. Appliances by4a.6a.2001

  1. appl_household2001.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorkingLos Alamos verifiesValidation of MFRSR0a. Appliances by4a.6a.20018a.

  2. appl_household2001.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorkingLos Alamos verifiesValidation of MFRSR0a. Appliances by4a.6a.20018a.9a.

  3. NREL 2012 Achievement of Ethanol Cost Targets: Biochemical Ethanol Fermentation via Dilute-Acid Pretreatment and Enzymatic Hydrolysis of Corn Stover

    SciTech Connect (OSTI)

    Tao, L.; Schell, D.; Davis, R.; Tan, E.; Elander, R.; Bratis, A.

    2014-04-01

    For the DOE Bioenergy Technologies Office, the annual State of Technology (SOT) assessment is an essential activity for quantifying the benefits of biochemical platform research. This assessment has historically allowed the impact of research progress achieved through targeted Bioenergy Technologies Office funding to be quantified in terms of economic improvements within the context of a fully integrated cellulosic ethanol production process. As such, progress toward the ultimate 2012 goal of demonstrating cost-competitive cellulosic ethanol technology can be tracked. With an assumed feedstock cost for corn stover of $58.50/ton this target has historically been set at $1.41/gal ethanol for conversion costs only (exclusive of feedstock) and $2.15/gal total production cost (inclusive of feedstock) or minimum ethanol selling price (MESP). This year, fully integrated cellulosic ethanol production data generated by National Renewable Energy Laboratory (NREL) researchers in their Integrated Biorefinery Research Facility (IBRF) successfully demonstrated performance commensurate with both the FY 2012 SOT MESP target of $2.15/gal (2007$, $58.50/ton feedstock cost) and the conversion target of $1.41/gal through core research and process improvements in pretreatment, enzymatic hydrolysis, and fermentation.

  4. The proportion of prostate biopsy tissue with Gleason pattern 4 or 5 predicts for biochemical and clinical outcome after radiotherapy for prostate cancer

    SciTech Connect (OSTI)

    D'Ambrosio, David J. [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Hanlon, Alexandra L. [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Al-Saleem, Tahseen [Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA (United States); Feigenberg, Steven J. [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Horwitz, Eric M. [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Uzzo, Robert G. [Department of Urologic Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Pollack, Alan [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Buyyounouski, Mark K. [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States)]. E-mail: mark.buyyounouski@fccc.edu

    2007-03-15

    Purpose: To investigate the prognostic utility of the proportion of prostate biopsy tissue containing Gleason pattern 4 or 5 (GP4/5) after definitive radiotherapy (RT) for prostate cancer. Methods and Materials: A total of 568 patients with T1c-3 Nx/0 prostate cancer who received three-dimensional conformal RT alone between May 1989 and August 2001 were studied. There were 161 men with Gleason score 7-10 disease. The GP4/5 was defined as the percentage of biopsy tissue containing Gleason pattern 4 or 5. A Cox proportional hazards model was used for univariate and multivariate analyses (MVA) for biochemical failure (BF) (American Society of Therapeutic Radiology and Oncology definition) and distant metastasis (DM). A recursive partitioning analysis was done using the results of the MVA to identify a cutpoint for GP4/5. Results: The median follow-up was 46 (range, 13-114) months and median RT dose was 76 (range, 65-82) Gy. On MVA, increasing initial prostate-specific antigen (p = 0.0248) decreasing RT dose (continuous, p = 0.0022), T stage (T1/2 vs. T3) (p = 0.0136) and GP4/5 (continuous, p < 0.0001) were significant predictors of BF in a model also containing GS. GP4/5 was the only significant predictor of DM in the same model (p < 0.0001). Conclusion: The GP4/5 in prostate biopsy specimens is a predictor of BF and DM after RT independent of Gleason score. This parameter should be reported by the pathologist when reviewing prostatic biopsy specimens.

  5. Evidence for posttranslational protein flavinylation in the syphilis spirochete Treponema pallidum: Structural and biochemical insights from the catalytic core of a periplasmic flavin-trafficking protein

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Deka, Ranjit K.; Brautigam, Chad A.; Liu, Wei Z.; Tomchick, Diana R.; Norgard, Michael V.

    2015-05-05

    The syphilis spirochete Treponema pallidum is an important human pathogen but a highly enigmatic bacterium that cannot be cultivated in vitro. T. pallidum lacks many biosynthetic pathways and therefore has evolved the capability to exploit host-derived metabolites via its periplasmic lipoprotein repertoire. We recently reported a flavin-trafficking protein in T. pallidum (Ftp_Tp; TP0796) as the first bacterial metal-dependent flavin adenine dinucleotide (FAD) pyrophosphatase that hydrolyzes FAD into AMP and flavin mononucleotide (FMN) in the spirochete’s periplasm. However, orthologs of Ftp_Tp from other bacteria appear to lack this hydrolytic activity; rather, they bind and flavinylate subunits of a cytoplasmic membrane redoxmore »system (Nqr/Rnf). To further explore this dichotomy, biochemical analyses, protein crystallography, and structure-based mutagenesis were used to show that a single amino acid change (N55Y) in Ftp_Tp converts it from an Mg²?-dependent FAD pyrophosphatase to an FAD-binding protein. We also demonstrated that Ftp_Tp has a second enzymatic activity (Mg²?-FMN transferase); it flavinylates protein(s) covalently with FMN on a threonine side chain of an appropriate sequence motif using FAD as the substrate. Moreover, mutation of a metal-binding residue (D284A) eliminates Ftp_Tp’s dual activities, thereby underscoring the role of Mg²? in the enzyme-catalyzed reactions. The posttranslational flavinylation activity that can target a periplasmic lipoprotein (TP0171) has not previously been described. The observed activities reveal the catalytic flexibility of a treponemal protein to perform multiple functions. Together, these findings imply mechanisms by which a dynamic pool of flavin cofactor is maintained and how flavoproteins are generated by Ftp_Tp locally in the T. pallidum periplasm.« less

  6. Biochemical & Thermochemical High Throughput Characterization...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    20 40 60 80 100 120 140 32 34 36 38 40 42 44 46 48 50 52 54 56 58 60 62 64 66 68 70 Frequency Corn Stover Corn Cob Miscanthus Wheat...

  7. Elvera Sofos BIOCHEM 118Q

    E-Print Network [OSTI]

    Brutlag, Doug

    and Development (R&D) is used as a valid excuse by the pharmaceutical industries for increasing prices it to the medicinal stage, since only 2% become commercial drugs.2 Thus, the time and energy spent on developing

  8. BioChem Cover story

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room News PublicationsAudits & InspectionsBeryllium and ChronicBestBeyondBigger'sReactionsLSU

  9. Biochemical Conversion | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels DataEnergy Webinar:I DueBETO Quiz -Technologies forBig SavingsConversion

  10. High Occurrence of Aberrant Lymph Node Spread on Magnetic Resonance Lymphography in Prostate Cancer Patients With a Biochemical Recurrence After Radical Prostatectomy

    SciTech Connect (OSTI)

    Meijer, Hanneke J.M., E-mail: H.Meijer@rther.umcn.nl [Department of Radiation Oncology, Radboud University Nijmegen Medical Center, Nijmegen (Netherlands); Lin, Emile N. van [Department of Radiation Oncology, Radboud University Nijmegen Medical Center, Nijmegen (Netherlands); Debats, Oscar A. [Department of Radiology, Radboud University Nijmegen Medical Center, Nijmegen (Netherlands); Witjes, J. Alfred [Department of Urology, Radboud University Nijmegen Medical Center, Nijmegen (Netherlands); Span, Paul N.; Kaanders, Johannes H.A.M. [Department of Radiation Oncology, Radboud University Nijmegen Medical Center, Nijmegen (Netherlands); Barentsz, Jelle O. [Department of Radiology, Radboud University Nijmegen Medical Center, Nijmegen (Netherlands)

    2012-03-15

    Purpose: To investigate the pattern of lymph node spread in prostate cancer patients with a biochemical recurrence after radical prostatectomy, eligible for salvage radiotherapy; and to determine whether the clinical target volume (CTV) for elective pelvic irradiation in the primary setting can be applied in the salvage setting for patients with (a high risk of) lymph node metastases. Methods and Materials: The charts of 47 prostate cancer patients with PSA recurrence after prostatectomy who had positive lymph nodes on magnetic resonance lymphography (MRL) were reviewed. Positive lymph nodes were assigned to a lymph node region according to the guidelines of the Radiation Therapy Oncology Group (RTOG) for delineation of the CTV for pelvic irradiation (RTOG-CTV). We defined four lymph node regions for positive nodes outside this RTOG-CTV: the para-aortal, proximal common iliac, pararectal, and paravesical regions. They were referred to as aberrant lymph node regions. For each patient, clinical and pathologic features were recorded, and their association with aberrant lymph drainage was investigated. The distribution of positive lymph nodes was analyzed separately for patients with a prostate-specific antigen (PSA) <1.0 ng/mL. Results: MRL detected positive aberrant lymph nodes in 37 patients (79%). In 20 patients (43%) a positive lymph node was found in the pararectal region. Higher PSA at the time of MRL was associated with the presence of positive lymph nodes in the para-aortic region (2.49 vs. 0.82 ng/mL; p = 0.007) and in the proximal common iliac region (1.95 vs. 0.59 ng/mL; p = 0.009). There were 18 patients with a PSA <1.0 ng/mL. Ten of these patients (61%) had at least one aberrant positive lymph node. Conclusion: Seventy-nine percent of the PSA-recurrent patients had at least one aberrant positive lymph node. Application of the standard RTOG-CTV for pelvic irradiation in the salvage setting therefore seems to be inappropriate.

  11. Impact of Neoadjuvant Prostate-Specific Antigen Kinetics on Biochemical Failure and Prostate Cancer Mortality: Results From a Prospective Patient Database

    SciTech Connect (OSTI)

    Foo, Marcus, E-mail: Marcus.Foo@petermac.org [Division of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne (Australia)] [Division of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne (Australia); Lavieri, Mariel [Department of Industrial and Operations Engineering, University of Michigan, Ann Arbor, Michigan (United States)] [Department of Industrial and Operations Engineering, University of Michigan, Ann Arbor, Michigan (United States); Pickles, Tom [Department of Radiation Oncology, British Columbia Cancer Agency, Vancouver, BC (Canada)] [Department of Radiation Oncology, British Columbia Cancer Agency, Vancouver, BC (Canada)

    2013-02-01

    Purpose: To confirm findings from an earlier report showing that neoadjuvant (NA) prostate-specific antigen (PSA) halving time (PSAHT) impacts biochemical failure (BF) rates, and to examine its association with prostate cancer-specific survival (PCSS), in a large prospective cohort of patients. Methods and Materials: A total of 502 patients were selected from a prospective database, who had localized prostate adenocarcinoma treated with 2-12 months of neoadjuvant androgen deprivation therapy (N-ADT) followed by external beam radiation therapy (EBRT) between 1994 and 2000, and had at least 2 NA PSA values. Seventy-four percent of patients had high-risk prostate cancer. Median initial PSA value, N-ADT duration, total ADT duration, and radiation therapy dose were 14 ng/mL, 6.9 months, 10.8 months, and 68 Gy, respectively. Results: At a median follow-up of 9.9 years, 210 patients have had a BF. Median PSAHT was 18 days. On univariate analysis, PSAHT was not shown to predict for BF (P=.69) or PCSS (P=.28). However, NA nadir PSA (nanPSA) and post-therapy nadir PSA (ptnPSA), when analyzed as continuous or categoric variables, predicted for BF (P<.001) and PCSS (P<.001). On multivariate analysis, nanPSA (P=.037) and ptnPSA (P<.001) continued to be significantly associated with BF. However, N-ADT duration lost significance (P=.67), and PSAHT remained a nonsignificant predictor (P=.97). For PCSS, multivariate analysis showed nanPSA (P=.049) and ptnPSA (P<.001) to be significant. Again PSAHT (P=.49) remained nonsignificant. Conclusions: In this large, prospective cohort of patients, NA PSA kinetics, expressed as PSAHT, did not predict BF or PCSS. However, nadir PSAs, in both the NA and post-therapy settings, were significant predictors of BF and PCSS. Optimization of therapy could potentially be based on early PSA response, with shorter durations of ADT for those predicted to do favorably, and intensification of therapy for those likely to have poorer outcomes.

  12. 2 2014 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Biotechnol. J. 2014, 9, 23 DOI 10.1002/biot.201300522

    E-Print Network [OSTI]

    fermentation steps, and re- port critical assessment of their ap- plicability to bioethanol production. In biorefinery research, microbial tolerance to toxic products and those chemicals present in biomass hy be an issue as it can affect the overall productivity. Delvigne and Goffin [5] review our current

  13. [14] a) H. Jia, G. Zhu, B. Vugrinovich, W. Kataphinan, D. H. Reneker, P. Wang, Biotechnol. Prog. 2002, 18, 1027. b) M. M. Demir, M. A.

    E-Print Network [OSTI]

    Li, Jing

    and efficient energy sources/carriers to replace fossil fuels. Seeking renewable energy sources/car- riersCann, Y. Xia, Small 2005, 1, 83. [18] T. Hongu, G. O. Phillips, New Fibres, 2nd ed., Horwood, Cambridge great potential to become one of the dominant energy carriers in the future. Moreover, the sole by

  14. METEOROLOGICAL APPLICATIONS Meteorol. Appl. 15: 318 (2008)

    E-Print Network [OSTI]

    Ebert, Beth

    2008-01-01

    of forecasting systems, or the desire for more meaningful verification approaches that address specific forecast operational modelling centres select model upgrades, or to help power companies make decisions on the purchaseScience (www.interscience.wiley.com) DOI: 10.1002/met.52 Review Forecast verification: current status

  15. Einstein's Apple: His First Principle of Equivalence

    E-Print Network [OSTI]

    Engelbert L. Schucking; Eugene J. Surowitz

    2012-08-09

    After a historical discussion of Einstein's 1907 principle of equivalence, a homogeneous gravitational field in Minkowski spacetime is constructed. It is pointed out that the reference frames in gravitational theory can be understood as spaces with a flat connection and torsion defined through teleparallelism. This kind of torsion was introduced by Einstein in 1928. The concept of torsion is discussed through simple examples and some historical observations.

  16. Einstein's Apple and Relativity's Gravitational Field

    E-Print Network [OSTI]

    Engelbert L. Schucking

    2009-03-31

    The foundations of Einstein's first (1907) principle of equivalence are explored and their consequences are stated in terms of invariance under generalized Lorentz transformations, first explored by Hessenberg.

  17. Hypodensity/Hyperdensity ; or, Apple skies

    E-Print Network [OSTI]

    Cira, Gabriel (Gabriel Blue)

    2008-01-01

    Hypodensity/Hyperdensity is a reaction to the paradoxical modern urban condition of emptiness: the 'ring of drek,' left like a smear around Boston by post-industrial deflation. This area is close to both the crowded city ...

  18. METEOROLOGICAL APPLICATIONS Meteorol. Appl. 00: 110 (0000)

    E-Print Network [OSTI]

    Reading, University of

    upon the uses of some recently-deployed meteorological sensing devices to investigate insect migratory of aerial insect biomass) was found to be positively correlated with maximum screen temperature. Copyright c movements using traditional entomological techniques. Thus, the deployment of special-purpose ento

  19. Insect and Mite Management in Apples

    E-Print Network [OSTI]

    Pittendrigh, Barry

    Reduced fruit set the following year #12;ERM Adult #12;#12;ERM Damage #12;Amblyseius fallacis #12ModerateHigh #12;ERM Management Dormant oil application Conserve predator mites Scout orchard regularly Look

  20. Published in J. Math. Anal. Appl.

    E-Print Network [OSTI]

    Vitolo, Raffaele

    - namici del continuo" and "Leggi di conservazione e termodinamica in meccanica dei continui e in teorie di

  1. Published in J. Math. Anal. Appl.

    E-Print Network [OSTI]

    Vitolo, Raffaele

    termodinamica in meccanica dei continui e in teorie di campo''), GNFM, GNSAGA, Universities of Lecce and Messina

  2. Appling County Pellets | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION JEnvironmental Jump to:EAandAmminex A S Jump to:AngolaEnergy Management JumpTechnologies

  3. Early Salvage Hormonal Therapy for Biochemical Failure Improved Survival in Prostate Cancer Patients After Neoadjuvant Hormonal Therapy Plus Radiation Therapy-A Secondary Analysis of Irish Clinical Oncology Research Group 97-01

    SciTech Connect (OSTI)

    Mydin, Aminudin R., E-mail: aminudinrahman@googlemail.com [Department of Radiotherapy and Oncology, Kuala Lumpur Hospital, Kuala Lumpur (Malaysia); Dunne, Mary T.; Finn, Marie A. [Clinical Trials Resource Unit, St. Luke's Hospital, Dublin (Ireland)] [Clinical Trials Resource Unit, St. Luke's Hospital, Dublin (Ireland); Armstrong, John G. [Department of Radiation Oncology, St. Luke's Hospital, Dublin (Ireland)] [Department of Radiation Oncology, St. Luke's Hospital, Dublin (Ireland)

    2013-01-01

    Purpose: To assess the survival benefit of early vs late salvage hormonal therapy (HT), we performed a secondary analysis on patients who developed recurrence from Irish Clinical Oncology Research Group 97-01, a randomized trial comparing 4 vs 8 months neoadjuvant HT plus radiation therapy (RT) in intermediate- and high-risk prostate adenocarcinoma. Methods and Materials: A total of 102 patients from the trial who recurred were analyzed at a median follow-up of 8.5 years. The patients were divided into 3 groups based on the timing of salvage HT: 57 patients had prostate-specific antigen (PSA) {<=}10 ng/mL and absent distant metastases (group 1, early), 21 patients had PSA >10 ng/mL and absent distant metastases (group 2, late), and 24 patients had distant metastases (group 3, late). The endpoint analyzed was overall survival (OS) calculated from 2 different time points: date of enrolment in the trial (OS1) and date of initiation of salvage HT (OS2). Survival was estimated using Kaplan-Meier curves and a Cox regression model. Results: The OS1 differed significantly between groups (P<.0005): OS1 at 10 years was 78% in group 1, 42% in group 2, and 29% in group 3. The OS2 also differed significantly between groups (P<.0005): OS2 at 6 years was 70% in group 1, 47% in group 2, and 22% in group 3. Group 1 had the longest median time from end of RT to biochemical failure compared with groups 2 and 3 (3.3, 0.9, and 1.7 years, respectively; P<.0005). Group 1 also had the longest median PSA doubling time compared with groups 2 and 3 (9.9, 3.6, and 2.4 months, respectively; P<.0005). On multivariate analysis, timing of salvage HT, time from end of RT to biochemical failure, and PSA nadir on salvage HT were significant predictors of survival. Conclusion: Early salvage HT based on PSA {<=}10 ng/mL and absent distant metastases improved survival in patients with prostate cancer after failure of initial treatment with neoadjuvant HT plus RT.

  4. Photonic Crystal Slot Waveguide Spectrometer for Detection of Methane

    E-Print Network [OSTI]

    Texas at Austin, University of

    Photonic Crystal Slot Waveguide Spectrometer for Detection of Methane 1 Funded by Environmental. of Electrical and Computer Engineering, University of Texas, Austin #12;Motivation No other chip based optical Similar to: Doping of Semiconductor 3 #12;4 Photonic Crystal Bio-Chemical Sensors Loncar et al, Appl. Phys

  5. Biochemically enhanced oil recovery and oil treatment

    DOE Patents [OSTI]

    Premuzic, Eugene T. (East Moriches, NY); Lin, Mow (Rocky Point, NY)

    1994-01-01

    This invention relates to the preparation of new, modified organisms, through challenge growth processes, that are viable in the extreme temperature, pressure and pH conditions and salt concentrations of an oil reservoir and that are suitable for use in microbial enhanced oil recovery. The modified microorganisms of the present invention are used to enhance oil recovery and remove sulfur compounds and metals from the crude oil.

  6. Biochemical and Genetic Characterization of Bacteriophage Holins 

    E-Print Network [OSTI]

    To, Kam Ho

    2013-11-06

    to program the end of the phage infection cycle with precise timing. Nevertheless, I report studies involving phenotypic analysis of a systematic library of clustered site-directed mutants of S105, and then conclude with experiments designed to probe...

  7. Algebraic methods for biochemical reaction network theory

    E-Print Network [OSTI]

    Shiu, Anne

    2010-01-01

    Petri net approach to persistence analysis in chemical reaction networks,Petri net approach to the study of persistence in chemical reaction networks.

  8. Biochemical Process Improvements & Synthetic Biology Validation...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    strategic and performance goals to convert biomass sugars (and other carbohydrate and lignin derivatives) to hydrocarbon fuels, as described in recent reports: - Davis, R. et...

  9. Biochemical Conversion: Using Hydrolysis, Fermentation, and Catalysis...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    hydrolyze the cellulose and hemicellulose in biomass to free the sugars for conversion. The program is working to identify the most productive, naturally occurring...

  10. Biochemical Lithography - Templating of supported lipid bilayers...

    Office of Scientific and Technical Information (OSTI)

    (SNL-NM), Albuquerque, NM (United States) Sponsoring Org: USDOE National Nuclear Security Administration (NNSA) Country of Publication: United States Language: English...

  11. Biochemically enhanced oil recovery and oil treatment

    DOE Patents [OSTI]

    Premuzic, E.T.; Lin, M.

    1994-03-29

    This invention relates to the preparation of new, modified organisms, through challenge growth processes, that are viable in the extreme temperature, pressure and pH conditions and salt concentrations of an oil reservoir and that are suitable for use in microbial enhanced oil recovery. The modified microorganisms of the present invention are used to enhance oil recovery and remove sulfur compounds and metals from the crude oil. 62 figures.

  12. Stochastic Control Analysis for Biochemical Reaction Systems

    E-Print Network [OSTI]

    Kyung Hyuk Kim; Herbert M. Sauro

    2009-08-21

    In this paper, we investigate how stochastic reaction processes are affected by external perturbations. We describe an extension of the deterministic metabolic control analysis (MCA) to the stochastic regime. We introduce stochastic sensitivities for mean and covariance values of reactant concentrations and reaction fluxes and show that there exist MCA-like summation theorems among these sensitivities. The summation theorems for flux variances are shown to depend on the size of the measurement time window ($\\epsilon$), within which reaction events are counted for measuring a single flux. The degree of the $\\epsilon$-dependency can become significant for processes involving multi-time-scale dynamics and is estimated by introducing a new measure of time scale separation. This $\\epsilon$-dependency is shown to be closely related to the power-law scaling observed in flux fluctuations in various complex networks. We propose a systematic way to control fluctuations of reactant concentrations while minimizing changes in mean concentration levels. Such orthogonal control is obtained by introducing a control vector indicating the strength and direction of parameter perturbations leading to a sensitive control. We also propose a possible implication in the control of flux fluctuation: The control distribution for flux fluctuations changes with the measurement time window size, $\\epsilon$. When a control engineer applies a specific control operation on a reaction system, the system can respond contrary to what is expected, depending on the time window size $\\epsilon$.

  13. Course 28123 Chemical/Biochemical Engineering Laboratory

    E-Print Network [OSTI]

    , membrane separation, ion exchange, heat exchanging, evaporation, crystallisation, centrifugation, liquid include: Liquid flow in pipes, gas flow, pump systems, flow in packed columns, agitation, aeration

  14. Biochemical Process Modeling and Simulation Presentation for...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Knott Cellulase Mechanism Seonah Kim LPMO Mechanism (QM) Christina Payne Enzyme Thermodynamics Lintao Bu Cellulase Studies Deanne Sammond Lignin Binding, Rosetta Heather Mayes...

  15. Biochemical diversity of betaines in earthworms

    SciTech Connect (OSTI)

    Liebeke, Manuel [Department of Surgery and Cancer, Imperial College London, Sir Alexander Fleming Building, London SW7 2AZ (United Kingdom)] [Department of Surgery and Cancer, Imperial College London, Sir Alexander Fleming Building, London SW7 2AZ (United Kingdom); Bundy, Jacob G., E-mail: j.bundy@imperial.ac.uk [Department of Surgery and Cancer, Imperial College London, Sir Alexander Fleming Building, London SW7 2AZ (United Kingdom)

    2013-01-25

    Highlights: ? We develop a method for rapid untargetted analysis of betaines. ? We profile betaines in a comparative study of ten earthworm species. ? Earthworms contain a surprisingly high number of different betaine metabolites. ? Earthworms contain betaines normally seen only in plants or marine animals. -- Abstract: The ability to accumulate osmoprotectant compounds, such as betaines, is an important evolutionary feature in many organisms. This is particularly the case for organisms that live in variable environments, which may have fluctuations in moisture and salinity levels. There is, surprisingly, very little known about betaines in soil invertebrates in general, and there is almost no information about earthworms – a group that are important ‘ecosystem engineers’ and key indicators of soil health. Here, we describe a fast and reliable {sup 1}H–{sup 13}C heteronuclear single quantum coherence (HSQC) 2D NMR approach for the metabolic profiling of a series of betaines and related metabolites in tissue extracts, and list {sup 1}H and {sup 13}C chemical shifts for the trimethylammonium signal for 23 such compounds. The analysis of ten different species from three different families (Lumbricidae, Megascolecidae and Glossoscolecidae) showed an unexpected diversity of betaines present in earthworms. In total ten betaines were identified, including hydroxyproline-betaine, proline-betaine, taurine-betaine, GABA-betaine and histidine-betaine, and a further eleven as-yet unassigned putative betaine metabolites detected. The findings clearly indicate a hitherto-unappreciated important role for betaine metabolism in earthworms.

  16. Converging biochemical pathways in psychiatric disorders

    E-Print Network [OSTI]

    Soda, Takahiro

    2012-01-01

    According to the World Health Organization, neuropsychiatric diseases account for approximately one third of years lost to disability. Yet, despite this huge disease burden, there is a lack of new treatments under development: ...

  17. Biochemical characterization of matrix Gla protein

    E-Print Network [OSTI]

    Villa, Francisco Alfredo

    2007-01-01

    associated with after demineralization. MGP was discoveredprotein in the acid demineralization extract of calcifiedprotein in the acid demineralization extract of bovine bone

  18. Transcriptome and Biochemical Analyses of Fungal Degradation...

    Office of Scientific and Technical Information (OSTI)

    proposal is aimed at identifying the enzymes which are known to depolymerize woody biomass. Fundamental understanding of how nature gains access to cellulose and hemicellulose...

  19. Huangshi Xinghua Biochemical Ltd | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QAsource History View NewTexas: Energy Resources JumpNew Jersey:Hopkinsville,AdvancedHowellHualalaiHuangshi Xinghua

  20. NREL: Biomass Research - Biochemical Conversion Capabilities

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMass map shines light on771/6/14 Contact:News Releases |NRELBiochemical Conversion

  1. 2009 Biochemical Conversion Platform Review Report

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:Financing ToolInternationalReport FY2014 -EnergyEnergySenior2007 Annualof Energy- Name and

  2. Biochemical Conversion - Biorefinery Integration | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative FuelsofProgram:Y-12Power, IncBio Centers Announcement at the National PressNews

  3. Biochemical Conversion Related Links | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels DataEnergy Webinar:I DueBETO Quiz -Technologies forBig SavingsConversion »

  4. Pharmaceutical digital marketing and governance: illicit actors and challenges to global patient safety and public health

    E-Print Network [OSTI]

    Mackey, Tim K; Liang, Bryan A

    2013-01-01

    next pharmaceutical marketing frontier. J Commer BiotechnolPharmaceutical digital marketing and governance: illicitPharmaceutical digital marketing and governance: illicit

  5. Rapid Evolution of Coral Proteins Responsible for Interaction with the Environment

    E-Print Network [OSTI]

    Voolstra, Christian R.

    2011-01-01

    AM (2010) Development and heat stress-induced transcriptomicTranscriptomic responses to heat stress and bleaching in thefaveolata) during heat stress. Mar Biotechnol (NY) 2: 533–

  6. Booly : a new data integration platform for systems biology

    E-Print Network [OSTI]

    Do, Long Hoang

    2010-01-01

    for enabling conceptual biology. Bioinformatics 2005, 21for data integration in biology. Trends Biotechnol 1999, 17(the unification of biology. The Gene Ontology Consortium.

  7. Carbon Accounting and Economic Model Uncertainty of Emissions from Biofuels-Induced Land Use Change

    E-Print Network [OSTI]

    Plevin, Richard J; Beckman, Jayson; Golub, Alla A; Witcover, Julie; O'??Hare, Michael

    2015-01-01

    of U.S. Croplands for Biofuels Increases Greenhouse GasesLife-Cycle Assessment of Biofuels. Environmental Science &cellulosic ethanol. Biotechnol Biofuels 6 (1), 51. Elliott,

  8. Biofuel alternatives to ethanol: pumping the microbial well

    E-Print Network [OSTI]

    Fortman, J. L.

    2010-01-01

    Y. (2007) Biodiesel from microalgae. Biotechnol. Adv. 25,fuel production using microalgae. J. Jpn. Pet. Inst. 48,Figure 1). Biodiesel from microalgae-derived lipids has been

  9. Strategies and Technologies for Improving Air Quality Around Ports

    E-Print Network [OSTI]

    Khan, Mohammad Yusuf

    2013-01-01

    Chisti, Y. Biodiesel from microalgae. Biotechnol. Adv. 2007,Y. Biodiesel from microalgae beats bioethanol. Trendsproprietary heterotrophic microalgae that grow in the dark.

  10. Bio-crude transcriptomics: Gene discovery and metabolic network reconstruction for the biosynthesis of the terpenome of the hydrocarbon oil-producing green alga, Botryococcus braunii race B (Showa)*

    E-Print Network [OSTI]

    2012-01-01

    2. Chisti Y: Biodiesel from microalgae. Biotechnol Adv 2007,Chisti Y: Biodiesel from microalgae beats bioethanol. TrendsRW, Flynn KJ: Placing microalgae on the biofuels priority

  11. Evolutionary Study of Genome Features in Cereals: a Focus on Endogenous Small RNA Generation

    E-Print Network [OSTI]

    Nohzadeh-Malakshah, Sahar

    2012-01-01

    overlapping genes in Metazoa. In BMC Genomics, pp. 174.B. (2012). Compressive genomics. In Nat Biotechnol , pp.Ibarra, J. (2011). Crop genomics: advances and applications.

  12. Interactions of Lignin and Hemicellulose and Effects on Biomass Deconstruction

    E-Print Network [OSTI]

    Li, Hongjia

    2012-01-01

    pretreated for bioethanol production. Biotechnol Biofuels.woody biomass for bioethanol production. Bioresources. 2011;feedstocks for production of bioethanol and other biofuels,

  13. The Gut Microbiota: Ecology and Function

    E-Print Network [OSTI]

    Willing, B.P.

    2011-01-01

    Biotechnol. Fuller, R. 1989. Probiotics in man and animals.studies of the impact of probiotics on a model gut symbiontuse of prebiotics and probiotics as supplements. Prebiotics

  14. Dieselzymes: development of a stable and methanol tolerant lipase for biodiesel production by directed evolution

    E-Print Network [OSTI]

    Korman, Tyler P; Sahachartsiri, Bobby; Charbonneau, David M; Huang, Grace L; Beauregard, Marc; Bowie, James U

    2013-01-01

    J, Campelo JM, Romero AA: Biodiesel as feasible petrol fueltowards ever greener biodiesel production. Biotechnol Adv 3.T, Bielecki S: Enzymatic biodiesel synthesis - key factors

  15. Biofuel alternatives to ethanol: pumping the microbial well

    E-Print Network [OSTI]

    Fortman, J. L.

    2010-01-01

    costs and benefits of biodiesel and ethanol biofuels. Proc.187 24 Fukuda, H. et al. (2001) Biodiesel fuel production by26 Chisti, Y. (2007) Biodiesel from microalgae. Biotechnol.

  16. DNA Aptamer Development for Detection of Atrazine and Protective Antigen Toxin Using Fluorescence Polarization

    E-Print Network [OSTI]

    Sanchez, Pablo Enrique

    2012-01-01

    in man. J Biotechnol. 44, 155-160. Vitale, G, Bernardi, L. ,also known as MEKs) (Vitale et al. , 2000). MEKs belong to a

  17. Plant and microbial research seeks biofuel production from lignocellulose

    E-Print Network [OSTI]

    Bartley, Laura E; Ronald, Pamela C

    2009-01-01

    sugar yields for biofuel production. Nat Biotechnol 25(7):research seeks biofuel production from lignocellulose A keylignocellulosic biofuel production and highlight scientific

  18. Redesign of metabolic pathways for photosynthetic production of n-butanol using cyanobacteria

    E-Print Network [OSTI]

    Lan, Ethan I.

    2013-01-01

    J.C. , Direct biofuel production from carbon dioxide. (Oralfor direct biofuel production from brown macroalgae. Science2012) Cyanobacterial biofuel production. J Biotechnol. Lan

  19. Manipulation of the Carbon Storage Regulator System for Metabolite Remodeling and Biofuel Production in Escherichia coli

    E-Print Network [OSTI]

    2012-01-01

    remodeling and biofuel production in Escherichia coli.JD: Advanced biofuel production in microbes. Biotechnol JJM, Gonzalez R: Biofuel production in Escherichia coli: the

  20. Genetic and biotechnological approaches for biofuel crop improvement.

    E-Print Network [OSTI]

    Vega-Sánchez, Miguel E; Ronald, Pamela C

    2010-01-01

    engineering for biofuel production: towards affordablebiomass feedstocks for biofuel production. Genome Biol 2008,sugar yields for biofuel production. Nat Biotechnol 2007,

  1. Please cite this article in press as: Baumbach, J. et al., CoryneRegNet 3.0--An interactive systems biology plat-form for the analysis of gene regulatory networks in corynebacteria and Escherichia coli, J. Biotechnol. (2007),

    E-Print Network [OSTI]

    Babu, M. Madan

    2007-01-01

    Please cite this article in press as: Baumbach, J. et al., CoryneRegNet 3.0--An interactive systems reserved. doi:10.1016/j.jbiotec.2006.12.012 #12;Please cite this article in press as: Baumbach, J. et al

  2. COBIOT-854; NO. OF PAGES 8 Please cite this article in press as: Lovley DR, Nevin KP. A shift in the current: New applications and concepts for microbe-electrode electron exchange, Curr Opin Biotechnol (2011), doi:10.1016/

    E-Print Network [OSTI]

    Lovley, Derek

    2011-01-01

    - trical power with microbial fuel cells over the last decade, some of the early optimism for power in aquatic sediments with benthic microbial fuel cells continues to be a promising application [5­8]. However, after some of the rather obvious design flaws in early microbial fuel cells were rectified, there has

  3. 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim 791 Biotechnol. J. 2010, 5, 791 DOI 10.1002/biot.201000262 www.biotechnology-journal.com

    E-Print Network [OSTI]

    . Since the advent of GMO and LMO about three decades ago, metabolic engineering has played a key role to achieve a number of goals such as production of drugs, chemicals, fuel and materials, or degradation single-cell organism) in vitro. To the public it may seem that scientists are play- ing God, which

  4. COBIOT-855; NO. OF PAGES 7 Please cite this article in press as: Rabaey K, et al. Metabolic and practical considerations on microbial electrosynthesis, Curr Opin Biotechnol (2011), doi:10.1016/j.copbio.2011.01.010

    E-Print Network [OSTI]

    Girguis, Peter R.

    2011-01-01

    of interest, additional electrons (i.e. reducing power) are often needed. Meanwhile, the past decade has seen the breakthrough of sustainable electricity sources such as solar and wind. Microbial electrosynthesis (MES) is at the nexus of both, as it uses electrical energy as source of reducing power for microorganisms. This review

  5. 2009 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim 1725 Biotechnol. J. 2009, 4, 17251739 DOI 10.1002/biot.200900127 www.biotechnology-journal.com

    E-Print Network [OSTI]

    Zhao, Huimin

    for sustainability and environ- ment-friendly industrial production systems, cou- pled with the depletion of crude oil reserves, and a growing world demand for raw materials and ener- gy, will continue to drive as white biotechnology, is the application of modern biotechnology to the sustainable production

  6. COBIOT-984; NO. OF PAGES 6 Please cite this article in press as: Wu M, Singh AK. Single-cell protein analysis, Curr Opin Biotechnol (2011), doi:10.1016/j.copbio.2011.11.023

    E-Print Network [OSTI]

    Singh, Anup

    2011-01-01

    COBIOT-984; NO. OF PAGES 6 Please cite this article in press as: Wu M, Singh AK. Single analysis Meiye Wu and Anup K Singh Heterogeneity of cellular systems has been widely recognized but only, Sandia National Laboratory, Livermore, CA 94550, United States Corresponding author: Singh, Anup K

  7. 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim 1317 Biotechnol. J. 2012, 7, 1317 DOI 10.1002/biot.201200346 www.biotechnology-journal.com

    E-Print Network [OSTI]

    . Natural resources, development of industry, and population density are key factors that influence in this regard can not been questioned. It is clear that bioenergy and bio- fuel cannot solve the world's energy has completely overlooked is the prog- ress in our knowledge of producing of biofuel and bioenergy

  8. Cognitive Enhancement? Why not worry instead about apple pie? 

    E-Print Network [OSTI]

    Govaart, Mirre Esther

    2009-11-26

    This thesis argues that the neuroethical debate regarding cognitive enhancement drugs, as it stands, expounds arguments that fail as a result of the success of the Extended Cognition thesis. Instead this thesis suggets ...

  9. U-202: Apple QuickTime Multiple Stack Overflow Vulnerabilities

    Broader source: Energy.gov [DOE]

    Visiting a maliciously crafted website may lead to an unexpected application termination or arbitrary code execution.

  10. CB ENCIi TEC APPL SCI Stuctual Dynamic Systems Computational Techniques

    E-Print Network [OSTI]

    Nagarajaiah, Satish

    Airport Terminal, Liquefied Natural Gas (LNG) Facility in Greece, C-1 Computer Center Building in Japan

  11. SIAM J. APPL. MATH. Vol. 47, No. 5, October 1987

    E-Print Network [OSTI]

    Gilsinn, David E.

    Mathematics 001 ASYMPTOTIC APPROXIMATIONS OF INTEGRAL MANIFOLDS* DAVID E. GILSINNf Abstract Multidegree result for center stable manifolds in Carr [2, p. 25]. 2. Statement of the main theorem. For the restStandards, Gaithersburg, Maryland 20899. 929 #12;930 DAVID E. GILSINN (H3) (H4) O, Y, Z are periodic in 0 with vector

  12. Appl. Phys. B 67, 433441 (1998) Applied Physics B

    E-Print Network [OSTI]

    Jimenez, Jose-Luis

    1998-01-01

    individual vehicle emissions by scaling the pol- lutant column density to the exhaust carbon dioxide column A tunable diode laser system for the remote sensing of on-road vehicle emissions D.D. Nelson1, M.S. Zahniser of non-cooperating vehicles. Remote sensing instruments using open path spectroscopy can monitor

  13. ANALOG-DIGITAL INPUT OUTPUT SYSTEM FOR APPLE CO

    E-Print Network [OSTI]

    Groppi, Christopher

    Initialization Program - ADIOS INITB Appendix 2 Test Program - ADIOS TEST Appendix 3 AND9513 Utilization Appendix HI-506A. Multiplexer F. Sprague UHP -507 Relay Driver G. Teledyne Solid-State Relays H. Advanced bus driver, a 4-bit relay driver, or two solid-state relays. Three of the digital output bits can

  14. Crunching Solar Numbers: The Big Apple Uses Big Data

    Office of Energy Efficiency and Renewable Energy (EERE)

    The City University of New York (CUNY) and its partners developed an analytics-based approach that makes it easier to spot key solar market indicators such as new permit applications and...

  15. Adding Apples and Oranges Martin Erwig and Margaret Burnett

    E-Print Network [OSTI]

    Erwig, Martin

    of spread- sheet contents on a more fine-grained level than types do. Also, because communication the fact that even commercial spread- sheet systems are indeed languages for programming, although can have serious consequences. For example, a Dallas oil and gas company lost millions of dollars

  16. Adding Apples and Oranges Martin Erwig and Margaret Burnett

    E-Print Network [OSTI]

    Erwig, Martin

    of spread­ sheet contents on a more fine­grained level than types do. Also, because communication the fact that even commercial spread­ sheet systems are indeed languages for programming, although they di can have serious consequences. For example, a Dallas oil and gas company lost millions of dollars

  17. SIAM J. APPL. MATH. Vol. 48, No. 2, April 1988

    E-Print Network [OSTI]

    Daripa, Prabir

    007 POLYMER FLOODS: A CASE STUDY OF NONLINEAR WAVE ANALYSIS AND OF INSTABILITY CONTROL IN TERTIARY OIL RECOVERY* PRABIR DARIPAf, JAMES GLIMM', BRENT LINDQUISTf, AND OLIVER McBRYANf Abstract. Polymer flooding of oil recovery for the polymer flood. The details of these two phenomena depend on the separation

  18. SIAM J. APPL. MATH. Voi. 48, No. 5, October 1988

    E-Print Network [OSTI]

    Temple, Blake

    Science Foundation grant DMS-831229, Department of Energy contract DE-AC02-76ER03077, by the University, and by CNPq/Brazil grant 403039/84-MA. $ Department of Mathematics, Pontificia Universidade Catolica do Rio de Janeiro, Rio de Janeiro, Brazil 22453. This work was supported in part by CNPq/Brazil fellowship 30

  19. From: Nicholas Ammann [mailto:nammann@apple.com

    Broader source: Energy.gov (indexed) [DOE]

    Tuesday, July 16, 2013 4:35 PM To: Exparte Communications Subject: Request for Information on Evaluating New Products for the Battery Chargers and External Power Supply Rulemaking...

  20. ENERGY COMMISSION APPL.lCATION FOR SOURCE MATERIAL LICENSE

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and700, 1.Reports1 Rev.Metals

  1. Appling County, Georgia: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION JEnvironmental Jump to:EAandAmminex A S Jump to:AngolaEnergy ManagementGeorgia: Energy Resources

  2. AMR Power Private Ltd APPL | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION JEnvironmental Jump to:EAand Dalton JumpProgramInformation ALLETE, Inc.EnergyPlc Jump

  3. From: Nicholas Ammann [mailto:nammann@apple.com]

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum12, 2015ExecutiveFluorescentDan O"Hagan To:JMulveny, JenniferTuesday, July

  4. From: Nicholas Ammann [mailto:nammann@apple.com]

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum12, 2015ExecutiveFluorescentDan O"Hagan To:JMulveny, JenniferTuesday,

  5. Innovative Hydropower Technology Now Powering an Apple Data Center |

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACT EVALUATION PLAN FOR0987P UncertaintyInitiativesInnovative

  6. Innovative Hydropower Technology Now Powering an Apple Data Center |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuelsof EnergyApril 2014 | Department ofInfrastructureDepartment of Energy

  7. Apples with apples: accounting for fuel price risk in comparisons of gas-fired and renewable generation

    SciTech Connect (OSTI)

    Bolinger, Mark; Wiser, Ryan

    2003-12-18

    For better or worse, natural gas has become the fuel of choice for new power plants being built across the United States. According to the US Energy Information Administration (EIA), natural gas combined-cycle and combustion turbine power plants accounted for 96% of the total generating capacity added in the US between 1999 and 2002--138 GW out of a total of 144 GW. Looking ahead, the EIA expects that gas-fired technology will account for 61% of the 355 GW new generating capacity projected to come on-line in the US up to 2025, increasing the nationwide market share of gas-fired generation from 18% in 2002 to 22% in 2025. While the data are specific to the US, natural gas-fired generation is making similar advances in other countries as well. Regardless of the explanation for (or interpretation of) the empirical findings, however, the basic implications remain the same: one should not blindly rely on gas price forecasts when comparing fixed-price renewable with variable-price gas-fired generation contracts. If there is a cost to hedging, gas price forecasts do not capture and account for it. Alternatively, if the forecasts are at risk of being biased or out of tune with the market, then one certainly would not want to use them as the basis for resource comparisons or investment decisions if a more certain source of data (forwards) existed. Accordingly, assuming that long-term price stability is valued, the most appropriate way to compare the levelized cost of these resources in both cases would be to use forward natural gas price data--i.e. prices that can be locked in to create price certainty--as opposed to uncertain natural gas price forecasts. This article suggests that had utilities and analysts in the US done so over the sample period from November 2000 to November 2003, they would have found gas-fired generation to be at least 0.3-0.6 cents/kWh more expensive (on a levelized cost basis) than otherwise thought. With some renewable resources, in particular wind power, now largely competitive with gas-fired generation in the US (including the impact of the federal production tax credit and current high gas prices), a margin of 0.3-0.6 cents/kWh may in some cases be enough to sway resource decisions in favor of renewables.

  8. Production of bioenergy and biochemicals from industrial and

    E-Print Network [OSTI]

    Angenent, Lars T.

    and agricultural wastewater, includ- ing methanogenic anaerobic digestion, biological hydro- gen production material in industrial and agricultural wastewater Methanogenic anaerobic digestion of organic material

  9. Bacteriophage ms2 l protein: genetic and biochemical characterization 

    E-Print Network [OSTI]

    McIntosh, Brenley Kathleen

    2009-05-15

    to release the progeny phages into the environment. MS2, the prototypic Levivirus, completes its entire lifecycle in about an hour, generating five hundred to one thousand plaque-forming units (p.f.u.) per cell (Paranchych et al., 1970; van Duin...

  10. MHK Projects/Modeling the Physical and Biochemical Influence...

    Open Energy Info (EERE)

    Deployed 0 Number of Build Out Units Deployed 0 Main Overseeing Organization Makai Ocean Engineering Inc Project Technology *MHK TechnologiesDeep Water Pipelines Project Timeline...

  11. Biochemical Platform Analysis Presentation for BETO 2015 Project...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    with NREL Catalytic Conversion of Sugars project - Q4 milestone * 2015 State of Technology assessment for FY15 R&D data - Q4 milestone * FY16 and beyond: TEA support for...

  12. Biochemical studies of vitamin B?? deficiency in the domestic fowl 

    E-Print Network [OSTI]

    Mohan, Vallury Surya

    1959-01-01

    knowledge of the period, the discipline, and the history of the Jesuits in this important volume. Kari McBride, ed. Domestic Arrangements in Early Modern England. Pittsburgh: Duquesne University Press, 2002. 342 pp. $60.00. Review by KAREN L. RABER... of representation were once regularly traced to the theater, they might now more correctly and profitably be traced instead to changes in the domestic realm. Although the essays in this volume do not always live up to this rather grand, but appropriate mandate...

  13. SCIENTIFIC PROFILES ROM. J. BIOCHEM., 48, 1, 512 (2011)

    E-Print Network [OSTI]

    2011-01-01

    to steer their interests to anti-viral therapies. As Barry said in his autobiography, "Professor Raymond

  14. Fluidic Microvalve Digital Processors for Automated Biochemical Analysis

    E-Print Network [OSTI]

    Jensen, Erik Christian

    2011-01-01

    for mixing. Non-laminar fluid flow during valve actuationFluid Dynamics Fluids typically have laminar flow profilesto the laminar flow profile of fluids within microchannels.

  15. A Language for Biochemical Systems Michael Pedersen and Gordon Plotkin

    E-Print Network [OSTI]

    Plotkin, Gordon

    of metabolic, signalling and regulatory networks in a natural and modular manner. In this paper we extend CBS and a translation to a variant of coloured Petri nets. Translation to other formalisms such as ordinary differential, large-scale, parameterised modules, subtyping, coloured Petri nets. 1 Introduction Recent years have

  16. A Language for Biochemical Systems: Design and Formal Specification

    E-Print Network [OSTI]

    Plotkin, Gordon

    and regulatory networks in terms of reactions between modified complexes, occurring concurrently inside semantical objects. Examples of such structures for the specific cases of Petri nets, coloured Petri nets, subtyping, combinato- rial explosion, nondeterminism, Petri nets, coloured Petri nets, ordinary differential

  17. FABRICATION TECHNOLOGY FOR NANOFLUIDIC CHANNEL DEVICES FOR BIOCHEMICAL APPLICATIONS

    E-Print Network [OSTI]

    van Vliet, Lucas J.

    of two glass wafers, in which nanochannels are created in the intermediate layer. The top glass wafer has technique used and the vertical dimensions are defined by the etching time of the intermediate layer have pre- drilled holes at predefined positions which serve as inlet or outlet of the channels. Sketch

  18. Biochemical maturation of the non-innervated chick optic lobe

    E-Print Network [OSTI]

    1978-01-01

    min/ mg wet tissue. The inulin space was estimated after14 C-antipyrine and 3H- inulin (875 mCi/ mM) as previouslytissue was found. Also, the inulin space of experimental

  19. Biobased Chemicals Landscape in 2015: What's the Role of Biochemicals...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    williamsbioenergy2015.pdf More Documents & Publications Methane and Methanotrophic Bacteria as a Biotechnological Platform Bioenergy 2015 Speaker Biographies Process Integration...

  20. A Microfluidic Microbial Fuel Cell as a Biochemical Oxygen Demand...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    emerged as a central technology in an attempt to produce electricity. In a BES, bacteria interact with electrodes using electrons, which are either removed or supplied...

  1. Biochemical and biophysical studies of MDM2-ligand interactions 

    E-Print Network [OSTI]

    Wang, Shao-Fang

    2012-06-22

    MDM2, murine double minute 2, is a RING type-E3 ligase protein and also an oncogene. MDM2 plays a critical role in determining the steady levels and activity of p53 in cells using two mechanisms. The N-terminal domain ...

  2. Biochemical aspects of vitamin E deficiency in fowl 

    E-Print Network [OSTI]

    Creech, Billy Gene

    1957-01-01

    IV) 4 0 to 0 w 0 ct- ** ?* 13 13 *<30405m CD ro H-r CCDV ? VOBIO CHE O O O O H H 1? 1 O N O D 0 0 U o ' O I V ) I V ) oo- roHH I-1no -r ?? H0 B...0 Pc+ c+O H-P c+ c+ 05B & ?rJo ^ H* H- 05 J3 0 kb td c+ H- < 0 O 105 6i k , , kb H-Pip' kb k2)9h* 05 B FO p. p. rs 0 k . H 1 *n!o

  3. Chemical and biochemical studies of ubiquitin conjugation machinery

    E-Print Network [OSTI]

    Pandya, Renuka K. (Renuka Kuchibhotla)

    2010-01-01

    The post-translational modification of proteins is a major mechanism employed in eukaryotic cells to expand the functional diversity of the proteome. Covalent modification of amino acid side chains confers new or altered ...

  4. Biobased Chemicals Landscape in 2015: What's the Role of Biochemicals...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    with breadth across markets, geographies, and retail applications * World-scale plastics facility * 2002 Winner - Presidential Green Chemistry Challenge * DOE partner...

  5. Maxwell's demon in biochemical signal transduction with feedback loop

    E-Print Network [OSTI]

    Sosuke Ito; Takahiro Sagawa

    2015-04-15

    Signal transduction in living cells is vital to maintain life itself, where information transfer in noisy environment plays a significant role. In a rather different context, the recent intensive researches of "Maxwell's demon" - a feedback controller that utilizes information of individual molecules - has led to a unified theory of information and thermodynamics. Here we combine these two streams of researches, and show that the second law of thermodynamics with information reveals the fundamental limit of the robustness of signal transduction against environmental fluctuations. Especially, we found that the degree of robustness is quantitatively characterized by an informational quantity called transfer entropy. Our information-thermodynamic approach is applicable to biological communication inside cells, in which there is no explicit channel coding in contrast to artificial communication. Our result would open up a novel biophysical approach to understand information processing in living systems on the basis of the fundamental information-thermodynamics link.

  6. Glycans in host-pathogen interactions : an integrated biochemical investigation

    E-Print Network [OSTI]

    Chandrasekaran, Aarthi

    2009-01-01

    The epithelial cell-extracellular matrix interface primarily comprises of complex glycans and glycoconjugates. The widespread distribution of these glycans on the epithelial cell surface makes them ideal targets for ...

  7. Genetic and Biochemical Characterization of Natural Tetracycline Biosynthesis

    E-Print Network [OSTI]

    Wang, Peng

    2013-01-01

    25 confirming the loss of a hydroxyl group at C6 by SsfO1confirming the loss of a hydroxyl group at C6. mAU nm Inten.featuring a signature C5 hydroxyl group. Unveiling of

  8. Genomics & Medicine http://biochem118.stanford.edu/

    E-Print Network [OSTI]

    Brutlag, Doug

    :407­42 #12;Variations in Tandem Repeat Arrays Human -Amylase Gene Repeats Sharp, Cheng & Eichler, Annu. Rev

  9. Computational Molecular Biology Biochem 218 BioMedical Informatics 231

    E-Print Network [OSTI]

    evolution? Which nodes are orthologous and which are paralogous bifurcations? · Do the trees show evidence vs. Colicin #12;· Protein DataBase o Multiple Structure Viewers o Sequence & Structure Comparison and Entire Database PDB Protein Database http://www.rcsb.org/pdb/ #12;PDB Protein Database http

  10. Biochemical Mechanisms and Energy Strategies of Geobacter Sulfurreduce...

    Office of Scientific and Technical Information (OSTI)

    Language: English Subject: 09 BIOMASS FUELS; 54 ENVIRONMENTAL SCIENCES metal reduction, microbial survival, energy metabolism Word Cloud More Like This Full Text preview image...

  11. Biochemical localization of a protein involved in Gluconacetobacter...

    Office of Scientific and Technical Information (OSTI)

    States Language: English Subject: 59 BASIC BIOLOGICAL SCIENCES biofuels (including algae and biomass), bio-inspired, membrane, carbon sequestration, materials and chemistry by...

  12. Computational Molecular Biology Biochem 218 BioMedical Informatics 231

    E-Print Network [OSTI]

    .edu/ Doug Brutlag Professor Emeritus Biochemistry & Medicine (by courtesy) The Human Genome Project #12 Gibson & Muse, A Primer of Genome Science http://www.sinauer.com/genomics/ #12;The Human Genome Project?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3294162 #12;Public Genome Assembly Process #12;BAC and PAC Libraries in Public Human Genome Project http

  13. Cells differentiate into distinct "types" Phenotypes: morphology, biochemical, mechanical,

    E-Print Network [OSTI]

    Sniadecki, Nathan J.

    Integins #12;4 Cadherins : a2+ g Transmembrane proteins Types: E-, N-, P-,VE-, andT-cadherin. #12;5 Adaptor proteins (e.g. b-catenin ) connect adherens junctions to actin filaments #12;6 Leukocyte rolling

  14. RUTGERS UNIVERSITY Department of Chemical and Biochemical Engineering

    E-Print Network [OSTI]

    Muzzio, Fernando J.

    to the design and analysis of chemical engineering separation processes. Distillation, liquid extraction, gas absorption, and membrane separation processes. Computer software for the design and analysis of various OF SEPARATION PROCESSES (3 credits) SPRING 2014 Professor: Marianthi Ierapetritou SOE, room C-232 (848) 445

  15. 45 2012-13SuggestedCoursePlan CHEMICAL (BIOCHEMICAL)

    E-Print Network [OSTI]

    Zhou, Chongwu

    & Statistics for Chemical Engineers or ISE 460: Engineering Economy CHE 442: Chemical Reactor Analysis CHE 443 GEN ED. II GEN ED. IV GEN ED. V GEN ED. VI ENGINEERING (48 UNITS) BME 410: Intro. to Biomaterials CHE 120: Intro. to Chemical Engineering CHE 205: Numerical Methods in Chemical Engineering CHE 330

  16. Genetic and Biochemical Analysis of Innate Immunity in Arabidopsis thaliana 

    E-Print Network [OSTI]

    Cheng, Cheng

    2013-11-08

    ) functions as a guardee to link Avr (effector) with R protein (guard) (Grant et al., 1995; Mackey et al., 2002). This model was proposed as the Guard Hypothesis (Bhattacharjee et al., 2011; Mackey et al., 8 2002). RIN4 could be phosphorylated by Avr..., and trigger downstream defense response (Axtell & Staskawicz, 2003; Mackey et al., 2003). Resistance genes Many of the resistance proteins are composed of Leucine-rich repeats (LRRs) and nucleotide-binding site (NBS) domains. However, some...

  17. Biochemical Feedstock Interface Presentation for BETO 2015 Project...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Technologies Office Goal Statement Goal: * Understand the impact of feedstock logistics & preprocessing on blend conversion performance Relevance to BETO and Industry: *...

  18. Financing Advanced Biofuels, Biochemicals And Biopower In Integrated Biorefineries

    Broader source: Energy.gov [DOE]

    Afternoon Plenary Session: Current Trends in the Advanced Bioindustry Bioenergy Project Finance Mechanisms—Mark Riedy, Counsel, Kilpatrick, Townsend & Stockton LLP

  19. Chip Scale Interferometry A micro fluidic platform for biochemical sensing

    E-Print Network [OSTI]

    Sørensen Department of Optics and Plasma Research, Risø National Laboratory, DK-4000 Roskilde, Denmark

  20. Application And Evaluation Of Biomagnetic And Biochemical Monitoring...

    Open Energy Info (EERE)

    of these leaves show promise as a bio-indicator of volcanic gas, aerosol and ash deposition on the flanks of Mt. Etna. For 2008, ICP-MS analysis of the elemental...