National Library of Energy BETA

Sample records for american lung association

  1. AmericanLungAssociationStateofLungDiseaseinDiverseCommunities2010 55 Lung Cancer

    E-Print Network [OSTI]

    Kaski, Samuel

    AmericanLungAssociationStateofLungDiseaseinDiverseCommunities2010 55 Lung Cancer Lung cancer is the uncontrolled growth of abnormal cells in one or both of the lungs . While normal cells reproduce and develop into healthy lung tissue, these abnormal cells reproduce faster and never grow into normal lung tissue . Lumps

  2. AMERICAN THORACIC SOCIETY PATIENT HEALTH SERIES Lung Cancer Prevention

    E-Print Network [OSTI]

    Kaski, Samuel

    AMERICAN THORACIC SOCIETY PATIENT HEALTH SERIES Lung Cancer Prevention What are the chances that I will develop lung cancer? The #1 cause of lung cancer is exposure to tobacco smoke. Your chances increase others (second-hand smoke), the greater your chances of developing lung cancer. People who have never

  3. American Association of Petroleum Geologists

    E-Print Network [OSTI]

    Kaufman, Alan Jay

    American Association of Petroleum Geologists 40th Eastern Section Meeting September 24-29, 2011 MEETING SPONSORS #12;2011 Eastern Section American Association of Petroleum Geologists 40th Annual Meeting

  4. Edinburgh Research Explorer Lung Microbiota Changes Associated with Chronic

    E-Print Network [OSTI]

    Millar, Andrew J.

    Edinburgh Research Explorer Lung Microbiota Changes Associated with Chronic Pseudomonas aeruginosa Lung Infection and the Impact of Intravenous Colistimethate Sodium Citation for published version, 'Lung Microbiota Changes Associated with Chronic Pseudomonas aeruginosa Lung Infection and the Impact

  5. American Gas Association | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    American Gas Association American Gas Association Memorandum Summarizing Ex Parte Communication 111011ExParte.pdf More Documents & Publications Ex Parte Memorandum - Natural...

  6. Native American Finance Officers Association Conference | Department...

    Office of Environmental Management (EM)

    Native American Finance Officers Association Conference Native American Finance Officers Association Conference March 5, 2012 - 5:50pm Addthis This event will take place on March...

  7. AMERICAN STATISTICAL ASSOCIATION (ASA)

    U.S. Energy Information Administration (EIA) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page| Open Energy Informationmonthly gasoline price to fall toUranium Marketing Annual ReportAMERICAN STATISTICAL

  8. Chinese American Faculty Association of Southern California

    E-Print Network [OSTI]

    Chang, Tu-nan

    Chinese American Faculty Association of Southern California CAFA Fall Picnic Date: October 27 picnic. Sincerely, Andy Yao Cindy Fang President, CAFA Vice-President, CAFA #12;Chinese American Faculty

  9. American Evaluation Association Guiding Principles for Evaluators

    SciTech Connect (OSTI)

    None

    2009-01-18

    Five principles developed by American Evaluation Associ intended to guide professional practice of evaluators & to inform evaluation clients and the general public about principles they can expect to be upheld by professional evaluators.

  10. The American Medical Association Foundation

    E-Print Network [OSTI]

    ;2 The Odontology Section of the American Academy of Forensic Sciences presented Robert Barsley, DDS, JD, Professor of Dentistry, with the Reidar Sognnaes AwardforExcellencein ForensicDentistry. This is another member in forensic dentistry­ the late Dr. Reidar Sognnaes ­ who was probably best known for disproving the theory

  11. American Gas Association Memorandum Summarizing Ex Parte Communication...

    Energy Savers [EERE]

    Memorandum Summarizing Ex Parte Communication American Gas Association Memorandum Summarizing Ex Parte Communication On October 9, 2014, a workshop was hosted by the American Gas...

  12. Genome-wide association study of lung function phenotypes in a founder population

    E-Print Network [OSTI]

    Abney, Mark

    Genome-wide association study of lung function phenotypes in a founder population Tsung-Chieh Yao, Detroit, Mich, Baltimore, Md, Madison, Wis, and Taoyuan, Taiwan Background: Lung function is a long) associated with lung function. Methods: We performed a genome-wide association study (GWAS) of FEV1, forced

  13. Factors Associated with Hepatitis B Testing Among Vietnamese Americans

    E-Print Network [OSTI]

    2010-01-01

    Asian American adults for hepatitis B: a cross-sectionalFactors Associated with Hepatitis B Testing Among VietnameseBACKGROUND: Chronic hepatitis B and hepatitis B- associated

  14. Telomere Length in Circulating Leukocytes Is Associated with Lung Function and Disease

    E-Print Network [OSTI]

    Nyholt, Dale R.

    Telomere Length in Circulating Leukocytes Is Associated with Lung Function and Disease Eva Albrecht. Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research, Munich, Germany

  15. CHINESE AMERICAN FACULTY ASSOCIATION OF SOUTHERN CALIFORNIA (CAFA)

    E-Print Network [OSTI]

    Chang, Tu-nan

    1 CHINESE AMERICAN FACULTY ASSOCIATION OF SOUTHERN CALIFORNIA (CAFA) NEWSLETTER, January 28, 2003 and Friends, Happy Chinese New Year! As your President and President-elect of the Chinese American Faculty

  16. Telomere length in circulating leukocytes is associated with lung function and

    E-Print Network [OSTI]

    Nyholt, Dale R.

    Telomere length in circulating leukocytes is associated with lung function and disease Eva Albrecht intrinsic age-related processes contribute to the interindividual variability of lung function. Our meta-analysis of 14 studies included 934 COPD cases with 15846 controls defined according to the Global Lungs

  17. American Wind Energy Association Wind Energy Finance and Investment Seminar

    Office of Energy Efficiency and Renewable Energy (EERE)

    The American Wind Energy Association Wind Energy Finance and Investment Seminar will be attended by representatives in the financial sector, businesses, bankers, government and other nonprofit...

  18. Management -Professional Associations American Management Association (AMA) : The AMA provides trainings and valuable resources to

    E-Print Network [OSTI]

    Management - Professional Associations American Management Association (AMA) : The AMA provides and experience. The Society for Human Resource Management (SHRM): SHRM is the world's largest association, dedicated to serving the needs of Human Resource Management Professionals. National Human Resources

  19. The respiratory health and lung function of Anglo-American children in a smelter town

    SciTech Connect (OSTI)

    Dodge, R.

    1983-02-01

    Cooper smelters are large, usually isolated, sources of air pollution. Arizona has several such plants on the periphery of small communities. The smelters emit predominantly sulfur oxides and particulates, and the residents of these communities intermittently are exposed to high concentrations (24-h sulfur dioxide (SO2) . 250 to 500 micrograms/m3) of smelter smoke but little other pollution. This study compared the respiratory health of Anglo-American school children who lived in one smelter community with children living in another small community in Arizona that was free of smelter air pollution. The prevalence of cough, as determined by questionnaire, was 25.6% in the smelter town children and 14.3% in the nonsmelter town children (p less than 0.05). Pulmonary function at the study onset was equal in the two groups. Over the course of the 4 yr of study, lung function growth (measured as actual forced expiratory volume in one second (FEV1) after 4 yr of study minus predicted FEV1) was also equal in the smelter town and nonsmelter town children. These results suggest that children in smelter communities have slightly more cough when compared with children living in other communities, but no differences in initial lung function or lung function at yearly testing over the period of the study.

  20. American Health Information Management Association Code of Ethics

    E-Print Network [OSTI]

    Zhou, Yaoqi

    1 American Health Information Management Association Code of Ethics Preamble The ethical obligations of the health information management (HIM) professional include the protection of patient privacy and confidential information; disclosure of information; development, use, and maintenance of health information

  1. QER- Comment of American Wind Energy Association 1

    Office of Energy Efficiency and Renewable Energy (EERE)

    Attached please find the comments of the American Wind Energy Association (AWEA) on the QER. Please don’t hesitate to contact me if you have any questions. Thank you. Tom

  2. Workplace Charging Challenge Partner: American Lung Association in Colorado

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergy Safely Tear DownEnergy| Department of

  3. Moore honored with American Statistical Association award

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformationJessework uses concrete7ModificationsMonitoring JobsBiodieselWebinarsAmerican

  4. Identifying HotSpots in Lung Cancer Data Using Association Rule Mining Ankit Agrawal and Alok Choudhary

    E-Print Network [OSTI]

    Kuzmanovic, Aleksandar

    Identifying HotSpots in Lung Cancer Data Using Association Rule Mining Ankit Agrawal and Alok, IL 60201, USA Email: {ankitag,choudhar}@eecs.northwestern.edu Abstract--We analyze the lung cancer. The resulting rules conform with existing biomedical knowledge and provide interesting insights into lung cancer

  5. American Gas Association | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative FuelsofProgram:Y-12 Beta-3AUDITLeslieAlgae BiomassServices »Money |ofAssociation

  6. The American Accounting Association (AAA): The American Accounting Association is the largest community of accountants in academia. Founded in 1916, the association shapes the future of accounting through teaching,

    E-Print Network [OSTI]

    Accounting The American Accounting Association (AAA): The American Accounting Association is the largest community of accountants in academia. Founded in 1916, the association shapes the future of accounting through teaching, research and a powerful network. (http://aaahq.org/) American Institute of CPAs

  7. Predicting the Risk of Secondary Lung Malignancies Associated With Whole-Breast Radiation Therapy

    SciTech Connect (OSTI)

    Ng, John; Shuryak, Igor; Xu Yanguang; Clifford Chao, K.S.; Brenner, David J.; Burri, Ryan J.

    2012-07-15

    Purpose: The risk of secondary lung malignancy (SLM) is a significant concern for women treated with whole-breast radiation therapy after breast-conserving surgery for early-stage breast cancer. In this study, a biologically based secondary malignancy model was used to quantify the risk of secondary lung malignancies (SLMs) associated with several common methods of delivering whole-breast radiation therapy (RT). Methods and Materials: Both supine and prone computed tomography simulations of 15 women with early breast cancer were used to generate standard fractionated and hypofractionated whole-breast RT treatment plans for each patient. Dose-volume histograms (DVHs) of the ipsilateral breast and lung were calculated for each patient on each plan. A model of spontaneous and radiation-induced carcinogenesis was used to determine the relative risks of SLMs for the different treatment techniques. Results: A higher risk of SLMs was predicted for supine breast irradiation when compared with prone breast irradiation for both the standard fractionation and hypofractionation schedules (relative risk [RR] = 2.59, 95% confidence interval (CI) = 2.30-2.88, and RR = 2.68, 95% CI = 2.39-2.98, respectively). No difference in risk of SLMs was noted between standard fractionation and hypofractionation schedules in either the supine position (RR = 1.05, 95% CI = 0.97-1.14) or the prone position (RR = 1.01, 95% CI = 0.88-1.15). Conclusions: Compared with supine whole-breast irradiation, prone breast irradiation is associated with a significantly lower predicted risk of secondary lung malignancy. In this modeling study, fractionation schedule did not have an impact on the risk of SLMs in women treated with whole-breast RT for early breast cancer.

  8. Lung cancer-derived Dickkopf1 is associated with bone metastasis and the mechanism involves the inhibition of osteoblast differentiation

    SciTech Connect (OSTI)

    Chu, Tianqing; Teng, Jiajun; Jiang, Liyan; Zhong, Hua; Han, Baohui

    2014-01-17

    Highlights: •DKK1 level was associated with NSCLC bone metastases. •Lung tumor cells derived DKK1 inhibited osteoblast differentiation. •Lung tumor cells derived DKK1 modulates ?-catenin and RUNX2. -- Abstract: Wnt/?-catenin signaling and Dickkopf1 (DKK1) play important roles in the progression of lung cancer, which preferably metastasizes to skeleton. But the role of them in bone dissemination is poorly understood. This study aims to define the role of DKK1 in lung cancer bone metastases and investigate the underlying mechanism. Our results demonstrated that DKK1 over-expression was a frequent event in non-small-cell lung cancer (NSCLC) blood samples, and serous DKK1 level was much higher in bone metastatic NSCLC compared to non-bone metastatic NSCLC. We also found that conditioned medium from DKK1 over-expressing lung cancer cells inhibited the differentiation of osteoblast, determined by alkaline phosphatase activity and osteocalcin secretion, whereas the conditioned medium from DKK1 silencing lung cancer cells exhibited the opposite effects. Mechanistically, DKK1 reduced the level of ?-catenin and RUNX2, as well as inhibiting the nuclear translocation of ?-catenin. Taken together, these results suggested that lung cancer-produced DKK1 may be an important mechanistic link between NSCLC and bone metastases, and targeting DKK1 may be an effective method to treat bone metastase of NSCLC.

  9. QER- Comment of American Public Power Association 1

    Broader source: Energy.gov [DOE]

    Attached are the American Public Power Association 's (APPA) statement for the April 11 QER public meeting, Duane Highley's statement for the same meeting since we reference it, and Sue Kelly's (APPA President & CEO) testimony from last Thursday's (April 10) Senate Energy and Natural Resources Committee hearing entitled "Keeping the Lights On – Are We Doing Enough to Ensure the Reliability and Security of the US Electric Grid?" since her testimony covers everything in regards to this meeting. Thank you in advance for your consideration of our attached documents for the QER. Please let me know if you have any questions. Best, Seth Seth Voyles Director, Government Relations 1875 Connecticut Ave., NW, Suite 1200, Washington, D.C. 20009-5715 www.publicpower.org

  10. Chinese American Faculty Association of Southern California (CAFA) Newsletter, January 16, 2001

    E-Print Network [OSTI]

    Chang, Tu-nan

    Chinese American Faculty Association of Southern California (CAFA) Newsletter, January 16, 2001! As your President and President-elect of the Chinese American Faculty Association of Southern California research findings on "Viral Hepatitis and Liver Cancer: Scourges of the Chinese?" We need your help

  11. Association of American Geographers Annual Meeting March 2009 Virtue Ethics for GIS Professionals

    E-Print Network [OSTI]

    Wright, Dawn Jeannine

    Geographers Annual Meeting March 2009 GISCI Ethics · GIS Certification Institute (2004) ·Code of Ethic11 Association of American Geographers Annual Meeting March 2009 Virtue Ethics for GIS, IN 47809 #12;22 Association of American Geographers Annual Meeting March 2009 Outline · Development

  12. Source apportionment of particulate matter in the US and associations with lung inflammatory markers

    SciTech Connect (OSTI)

    Duvall, R.M.; Norris, G.A.; Dailey, L.A.; Burke, J.M.; McGee, J.K.; Gilmour, M.I.; Gordon, T.; Devlin, R.B.

    2008-07-01

    Size-fractionated particulate matter (PM) samples were collected from six U.S. cities and chemically analyzed as part of the Multiple Air Pollutant Study. Particles were administered to cultured lung cells and the production of three different proinflammatory markers was measured to explore the association between the health effect markers and PM. Ultrafine, fine, and coarse PM samples were collected between December 2003 and May 2004 over a 4-wk period in each city. Filters were pooled for each city and the PM samples were extracted then analyzed for trace metals, ions, and elemental carbon. Particle extracts were applied to cultured human primary airway epithelial cells, and the secreted levels of interleukin-8 (IL-8), heme oxygenase-1, and cyclooxygenase-2 were measured 1 and 24 h following exposure. Fine PM sources were quantified by the chemical mass balance (CMB) model. The relationship between toxicological measures, PM sources, and individual species were evaluated using linear regression. Ultrafine and fine PM mass were associated with increases in IL-8 (r{sup 2} = .80 for ultrafine and r{sup 2} = .52 for fine). Sources of fine PM and their relative contributions varied across the sampling sites and a strong linear association was observed between IL-8 and secondary sulfate from coal combustion (r{sup 2} = .79). Ultrafine vanadium, lead, copper, and sulfate were also associated with increases in IL-8. Increases in inflammatory markers were not observed for coarse PM mass and source markers. These findings suggest that certain PM size fractions and sources are associated with markers of lung injury or inflammation.

  13. American Association for Artificial Intelligence Spring Symposium 3/2004, Stanford University Keynote Lecture. FFrroomm HHuummaann EEmmoottiioonnss ttoo RRoobboott EEmmoottiioonnss

    E-Print Network [OSTI]

    Fellous, Jean-Marc

    1 American Association for Artificial Intelligence ­ Spring Symposium 3/2004, Stanford University © 2004, American Association for Artificial Intelligence (www.aaai.org). All rights reserved. open a new

  14. 2007 American Coal Ash Association membership directory as of June 21, 2007

    SciTech Connect (OSTI)

    2007-07-01

    A listing of names, addresses, contact numbers and websites is given for 101 members of the American Coal Ash Association. Honorary members are also named. Included are power generation companies, combustion by-product manufacturers and university departments.

  15. Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study

    E-Print Network [OSTI]

    Niu, Nifang

    Background: Taxane is one of the first line treatments of lung cancer. In order to identify novel single nucleotide polymorphisms (SNPs) that might contribute to taxane response, we performed a genome-wide association study ...

  16. Journal of the American Mosquito Control Association, 22(1):165173, 2006 Copyright 2006 by the American Mosquito Control Association, Inc.

    E-Print Network [OSTI]

    Ishida, Yuko

    by the American Mosquito Control Association, Inc. MEMORIAL LECTURE WILLIAM EMERY HAZELTINE II: REBEL WITH A CAUSE of California, Davis, CA 95616 Today we honor a man who made a difference. He was a medical entomologist who had in the chem- ical control of mosquitoes. Actually, Bill and I had much in common. We were both born and raised

  17. FOR IMMEDIATE RELEASE: USC Asian Pacific Alumni Association to Honor First Asian American Justice on the

    E-Print Network [OSTI]

    Zhou, Chongwu

    Asia and the Pacific Rim) with USC and one another lifelong and worldwide through programsFOR IMMEDIATE RELEASE: USC Asian Pacific Alumni Association to Honor First Asian American Justice USC Asian Pacific Alumni Association Scholarship and Awards Gala: "Foundations of Excellence" on April

  18. Comments of the Southern Environmental Law Center and the American Lung

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustmentsShirleyEnergy A plug-in electric vehicle (PEV)Day-June 22, 2015 |AT&TTheInformationAssociation

  19. CDK-associated Cullin 1 promotes cell proliferation with activation of ERK1/2 in human lung cancer A549 cells

    SciTech Connect (OSTI)

    Chen, Tian Jun; Gao, Fei; Yang, Tian; Thakur, Asmitanand; Ren, Hui; Li, Yang; Zhang, Shuo; Wang, Ting; Chen, Ming Wei

    2013-07-19

    Highlights: •CDK-associated Cullin 1 (CAC1) expression increases in human lung carcinoma. •CAC1 promotes the proliferation of lung cancer A549 cells. •CAC1 promotes human lung cancer A549 cell proliferation with activation of ERK1/2. -- Abstract: Lung cancer is one of the most common causes of cancer-related death in the world, but the mechanisms remain unknown. In this study, we investigated the expression of CDK-associated Cullin 1 (CAC1) in lung cancer, the effect of CAC1 on the proliferation of human lung cancer A549 cells, and the activation of signaling pathways of mitogen-activated protein kinases (MAPKs). Results showed that CAC1 expression was higher levels in human lung carcinoma than normal lung tissue, and CAC1 siRNA reduced the proliferation of lung cancer A549 cells by decreasing cell activity and cell division in vitro. The proportion of cells treated with CAC1 siRNA increased in the G1 phase and decreased in the S and G2/M phase, indicative of G1 cell cycle arrest. Furthermore, the proportions of early/late apoptosis in lung cancer A549 cells were enhanced with CAC1 siRNA treatment. It was also found that activation of extracellular signal-regulated protein kinase (ERK) and p38 signaling pathways were involved in the proliferation of A549 cells. After CAC1 siRNA treatment, p-ERK1/2 levels decreased, and meanwhile p-p38 level increased, A549 cell proliferation increased when ERK1/2 signaling is activated by PMA. Our findings demonstrated that CAC1 promoted the proliferation of human lung cancer A549 cells with activation of ERK1/2 signaling pathways, suggesting a potential cure target for treatment of human lung cancer.

  20. Comment submitted by the North American Association of Food Equipment Manufacturers (NAFEM) regarding the Energy Star Verification Testing Program

    Broader source: Energy.gov [DOE]

    This document is a comment submitted by the North American Association of Food Equipment Manufacturers (NAFEM) regarding the Energy Star Verification Testing Program

  1. American Wind Energy Association (AWEA) | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION J APPENDIX E LISTStar Energy LLC Jump to: navigation, search Name:AmbataSkiesPowerNetAmericanAWEA)

  2. Aerosol Science and Technology, 48:803812, 2014 Copyright C American Association for Aerosol Research

    E-Print Network [OSTI]

    Aerosol Science and Technology, 48:803­812, 2014 Copyright C American Association for Aerosol of particle growth in the atmosphere, and many properties of the resulting mixed particles depend on organic. In this article, analytic equations are derived p(;d) for condensational growth in a continuously mixed flow

  3. Aerosol Science and Technology, 43:641652, 2009 Copyright American Association for Aerosol Research

    E-Print Network [OSTI]

    Aerosol Science and Technology, 43:641­652, 2009 Copyright © American Association for Aerosol Differential Mobility Analyzer for Measurement of the Irreversibility of the Hygroscopic Growth Factor T is the irreversibility of the hygroscopic growth fac- tor of aerosol particles. The instrument uses the hysteresis

  4. Aerosol Science and Technology, 45:244261, 2011 Copyright American Association for Aerosol Research

    E-Print Network [OSTI]

    Aerosol Science and Technology, 45:244­261, 2011 Copyright © American Association for Aerosol University, Cambridge, Massachusetts, USA The hygroscopic phase transitions and growth factors of mixed chemical composition on phase transitions. The hygroscopic growth factors of the mixed particles were

  5. American Wind Energy Association, Denver, May 2005 Uncertainties in Results of Measure-Correlate-Predict Analyses

    E-Print Network [OSTI]

    Massachusetts at Amherst, University of

    American Wind Energy Association, Denver, May 2005 Uncertainties in Results of Measure-correlate-predict (MCP) algorithms are used to predict the wind resource at target sites for wind power development. MCP methods model the relationship between wind data (speed and direction) measured at the target site

  6. South Carolina graduates are getting jobs. Even in a period that the American Bar Association

    E-Print Network [OSTI]

    Almor, Amit

    South Carolina graduates are getting jobs. Even in a period that the American Bar Association paths in the law, sponsor a yearly"Career Week" with South Carolina law alumni each spring, offer a mock/non-profit 3 Business 37 $32,000-$105,000 Academic 2 not available 2012 South Carolina Bar Passage Rate 153

  7. is a program of the Association of American Medical Colleges and related

    E-Print Network [OSTI]

    Zhou, Xianghong Jasmine

    MCAT® is a program of the Association of American Medical Colleges and related trademarks owned's Doctors Preview Guide for the MCAT2015 Exam (Second Edition) September 2012 #12;This is the second edition for the MCAT2015 Exam (Second Edition) © 2012 AAMC. May not be reproduced without permission. 1 Table

  8. Copyright 1983 by the American Psychological Association, Inc.

    E-Print Network [OSTI]

    Timberlake, William D.

    of associations, and the study of the adaptive, regulatory functions of behavior. Until recently sessionsunder stingy schedules. The renewed interest in a regulatory ap- proach can be attributed a regulatory framework. The capacity to learn evolved and is typically expressedas an adaptive mechanism

  9. Association Between White Blood Cell Count Following Radiation Therapy With Radiation Pneumonitis in Non-Small Cell Lung Cancer

    SciTech Connect (OSTI)

    Tang, Chad; Gomez, Daniel R. [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Wang, Hongmei [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou (China); Levy, Lawrence B. [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Zhuang, Yan [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Xu, Ting; Nguyen, Quynh; Komaki, Ritsuko [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Liao, Zhongxing, E-mail: zliao@mdanderson.org [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States)

    2014-02-01

    Purpose: Radiation pneumonitis (RP) is an inflammatory response to radiation therapy (RT). We assessed the association between RP and white blood cell (WBC) count, an established metric of systemic inflammation, after RT for non-small cell lung cancer. Methods and Materials: We retrospectively analyzed 366 patients with non-small cell lung cancer who received ?60 Gy as definitive therapy. The primary endpoint was whether WBC count after RT (defined as 2 weeks through 3 months after RT completion) was associated with grade ?3 or grade ?2 RP. Median lung volume receiving ?20 Gy (V{sub 20}) was 31%, and post-RT WBC counts ranged from 1.7 to 21.2 × 10{sup 3} WBCs/?L. Odds ratios (ORs) associating clinical variables and post-RT WBC counts with RP were calculated via logistic regression. A recursive-partitioning algorithm was used to define optimal post-RT WBC count cut points. Results: Post-RT WBC counts were significantly higher in patients with grade ?3 RP than without (P<.05). Optimal cut points for post-RT WBC count were found to be 7.4 and 8.0 × 10{sup 3}/?L for grade ?3 and ?2 RP, respectively. Univariate analysis revealed significant associations between post-RT WBC count and grade ?3 (n=46, OR=2.6, 95% confidence interval [CI] 1.4?4.9, P=.003) and grade ?2 RP (n=164, OR=2.0, 95% CI 1.2?3.4, P=.01). This association held in a stepwise multivariate regression. Of note, V{sub 20} was found to be significantly associated with grade ?2 RP (OR=2.2, 95% CI 1.2?3.4, P=.01) and trended toward significance for grade ?3 RP (OR=1.9, 95% CI 1.0-3.5, P=.06). Conclusions: Post-RT WBC counts were significantly and independently associated with RP and have potential utility as a diagnostic or predictive marker for this toxicity.

  10. The association between fatalistic beliefs and late stage at diagnosis of lung and colorectal cancer

    E-Print Network [OSTI]

    Lyratzopoulos, Georgios; Liu, Michael Pang-Hsiang; Abel, Gary A.; Wardle, Jane; Keating, Nancy L.

    2015-02-03

    design and participants: The CanCORS (Cancer Care Outcomes Research and Surveillance) study prospectively enrolled U.S. adults diagnosed with lung or colorectal cancer in 2003-2005 who lived in certain geographic areas (northern California; Los Angeles... multiple imputation as previously described (19), were used in the logistic regression models, and outputs were combined with the SAS MIANALYZE procedure. In the present analysis imputed data only relate to the small proportion of records with missing...

  11. Adjuvant and Salvage Radiation Therapy After Prostatectomy: American Society for Radiation Oncology/American Urological Association Guidelines

    SciTech Connect (OSTI)

    Valicenti, Richard K., E-mail: Richard.valicenti@ucdmc.ucdavis.edu [Department of Radiation Oncology, University of California, Davis School of Medicine, Davis, California (United States); Thompson, Ian [Department of Urology, University of Texas Health Science Center at San Antonio, San Antonio, Texas (United States); Albertsen, Peter [Division of Urology, University of Connecticut Health Center, Farmington, Connecticut (United States); Davis, Brian J. [Department of Radiation Oncology, Mayo Medical School, Rochester, Minnesota (United States); Goldenberg, S. Larry [Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia (Canada); Wolf, J. Stuart [Department of Urology, University of Michigan, Ann Arbor, Michigan (United States); Sartor, Oliver [Department of Medicine and Urology, Tulane Medical School, New Orleans, Louisiana (United States); Klein, Eric [Glickman Urological Kidney Institute, Cleveland Clinic, Cleveland, Ohio (United States); Hahn, Carol [Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina (United States); Michalski, Jeff [Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri (United States); Roach, Mack [Department of Radiation Oncology, University of California, San Francisco, San Francisco, California (United States); Faraday, Martha M. [Four Oaks, Inc (United States)

    2013-08-01

    Purpose: The purpose of this guideline was to provide a clinical framework for the use of radiation therapy after radical prostatectomy as adjuvant or salvage therapy. Methods and Materials: A systematic literature review using PubMed, Embase, and Cochrane database was conducted to identify peer-reviewed publications relevant to the use of radiation therapy after prostatectomy. The review yielded 294 articles; these publications were used to create the evidence-based guideline statements. Additional guidance is provided as Clinical Principles when insufficient evidence existed. Results: Guideline statements are provided for patient counseling, use of radiation therapy in the adjuvant and salvage contexts, defining biochemical recurrence, and conducting a restaging evaluation. Conclusions: Physicians should offer adjuvant radiation therapy to patients with adverse pathologic findings at prostatectomy (ie, seminal vesicle invastion, positive surgical margins, extraprostatic extension) and salvage radiation therapy to patients with prostate-specific antigen (PSA) or local recurrence after prostatectomy in whom there is no evidence of distant metastatic disease. The offer of radiation therapy should be made in the context of a thoughtful discussion of possible short- and long-term side effects of radiation therapy as well as the potential benefits of preventing recurrence. The decision to administer radiation therapy should be made by the patient and the multidisciplinary treatment team with full consideration of the patient's history, values, preferences, quality of life, and functional status. The American Society for Radiation Oncology and American Urological Association websites show this guideline in its entirety, including the full literature review.

  12. Complications associated with brachytherapy alone or with laser in lung cancer

    SciTech Connect (OSTI)

    Khanavkar, B.; Stern, P.; Alberti, W.; Nakhosteen, J.A. )

    1991-05-01

    Relatively little has been reported about destruction through brachytherapy of mucosa-perforating and extraluminary tumors with probable large vessel involvement causing major hemorrhagic or fistular complications. We report 12 patients subjected to laser and brachytherapy for centrally occluding lung cancer, whom we have periodically followed up from June 1986 until they died. Although all laser procedures were free from complications, necrotic cavitation in five cases, two of which were accompanied by large bronchoesophageal fistulas, and massive fatal hemoptysis occurred in six. Minor complications included radiation mucositis (two), noncritical mucosal scarring (two), and cough (four). Characteristics that will identify patients at risk of developing fatal hemoptysis and fistulas should be better defined by imaging and endoscopic techniques. In such cases, modifying the protocol or using alternative procedures should be considered. Minor complications, such as cough, can be avoided by using topical steroid therapy (eg, beclomethasone dipropionate).

  13. Journal of the American Mosquito Control Assctciation, 17(2):I42-l43,2OOl Copyright O 2001 by the American Mosquito Control Association, Inc.

    E-Print Network [OSTI]

    by the American Mosquito Control Association, Inc. USE OF AN INFUSION-BAITED GRAVID TRAP TO COLLECT ADULT and collection methods have been ineffective. Infusion-baited gravid traps, typically intended to attract Culex. Both grass and hay infusions were used as attractants. The infusions were made by placing ap

  14. Journal of the American Mosquito Control Association, l8(4):2g}-2g3,2002 Copyright @ 2OO2by the American Mosquito Control Association,Inc.

    E-Print Network [OSTI]

    the American Mosquito Control Association,Inc. THE STRUCTURE AND FUNCTION OF THE LARVAL SIPHON AND SPIRACULAR of the larval siphon and spiracular apparatus of Coquillettidia perturbans and the mechanism of attachment. perturbans pierce with their specialized siphon and spiraculir apparatus to breithe. The siphon contains

  15. Organization Web Link American Association for Retired Person's http://www.grandfactsheets.org/doc/oklahoma07-final.pdf

    E-Print Network [OSTI]

    Veiga, Pedro Manuel Barbosa

    Organization Web Link American Association for Retired Person's http://www.grandfactsheets.org/doc/oklahoma-572-6831 Address: 1414 S. Division, Guthrie, OK 73044 Phone: 405-264-2700 , 800-572-6831 Oklahoma, North Address: 2409 N. Kelly, P.O. Box 26768, Oklahoma City, OK 73126 Phone: 405-522-5818, 800-884-1534 Address: 2409

  16. Functional Promoter Variant rs2868371 of HSPB1 Is Associated With Risk of Radiation Pneumonitis After Chemoradiation for Non-Small Cell Lung Cancer

    SciTech Connect (OSTI)

    Pang, Qingsong; Department of Radiation Oncology and Lung Cancer Center, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Cancer Prevention and Therapy, Tianjin ; Wei, Qingyi; Xu, Ting; Yuan, Xianglin; Lopez Guerra, Jose Luis; Levy, Lawrence B.; Liu, Zhensheng; Gomez, Daniel R.; Zhuang, Yan; Wang, Li-E.; Mohan, Radhe; Komaki, Ritsuko; Liao, Zhongxing

    2013-04-01

    Purpose: To date, no biomarkers have been found to predict, before treatment, which patients will develop radiation pneumonitis (RP), a potentially fatal toxicity, after chemoradiation for lung cancer. We investigated potential associations between single nucleotide polymorphisms (SNPs) in HSPB1 and risk of RP after chemoradiation for non-small cell lung cancer (NSCLC). Methods and Materials: Subjects were patients with NSCLC treated with chemoradiation at 1 institution. The training data set comprised 146 patients treated from 1999 to July 2004; the validation data set was 125 patients treated from August 2004 to March 2010. We genotyped 2 functional SNPs of HSPB1 (rs2868370 and rs2868371) from all patients. We used Kaplan-Meier analysis to assess the risk of grade ?2 or ?3 RP in both data sets and a parametric log-logistic survival model to evaluate the association of HSPB1 genotypes with that risk. Results: Grade ?3 RP was experienced by 13% of those with CG/GG and 29% of those with CC genotype of HSPB1 rs2868371 in the training data set (P=.028); corresponding rates in the validation data set were 2% CG/GG and 14% CC (P=.02). Univariate and multivariate analysis confirmed the association of CC of HSPB1 rs2868371 with higher risk of grade ?3 RP than CG/GG after adjustment for sex, age, performance status, and lung mean dose. This association was validated both in the validation data set and with Harrell's C statistic. Conclusions: The CC genotype of HSPB1 rs2868371 was associated with severe RP after chemoradiation for NSCLC.

  17. EV Community Readiness projects: American Lung Association of the Southwest (CO); Oregon Business Development Department (OR, WA)

    Broader source: Energy.gov [DOE]

    2013 DOE Hydrogen and Fuel Cells Program and Vehicle Technologies Program Annual Merit Review and Peer Evaluation Meeting

  18. Factors Associated With Severe Acute Esophagitis From Hyperfractionated Radiotherapy With Concurrent Chemotherapy for Limited-Stage Small-Cell Lung Cancer

    SciTech Connect (OSTI)

    Watkins, John M. [Department of Radiation Oncology, Medical University of South Carolina, Charleston, South Carolina (United States); Wahlquist, Amy E. M.S. [Department of Biostatistics, Bioinformatics, and Epidemiology, Medical University of South Carolina, Charleston, South Carolina (United States); Shirai, Keisuke [Department of Medicine, Division of Hematology and Oncology, Medical University of South Carolina, Charleston, South Carolina (United States); Garrett-Mayer, Elizabeth [Department of Radiation Oncology, Medical University of South Carolina, Charleston, South Carolina (United States); Department of Biostatistics, Bioinformatics, and Epidemiology, Medical University of South Carolina, Charleston, South Carolina (United States); Aguero, Eric G.; Fortney, John A. [Department of Radiation Oncology, Medical University of South Carolina, Charleston, South Carolina (United States); Sherman, Carol A. [Department of Medicine, Division of Hematology and Oncology, Medical University of South Carolina, Charleston, South Carolina (United States); Sharma, Anand K. [Department of Radiation Oncology, Medical University of South Carolina, Charleston, South Carolina (United States)], E-mail: sharmaak@musc.edu

    2009-07-15

    Purpose: To describe incidence and identify factors associated with development of severe acute esophagitis during hyperfractionated radiotherapy with concurrent chemotherapy (BID-CRT) in patients with limited-stage small-cell lung cancer (SCLC). Methods and Materials: Retrospective cohort analysis of patient-, tumor-, and treatment-related variables was performed to identify factors associated with Radiation Therapy Oncology Group (RTOG) Grade 3 acute esophagitis. Twice-daily chemoradiotherapy (BID-CRT) involved 45 Gy at 1.5 Gy per fraction, treated twice daily with concurrent platinum-based chemotherapy. Logistic regression analyses were used to identify factors associated with esophagitis. Results: Between June 1999 and June 2007, 48 patients underwent curative intent BID-CRT for SCLC and were included in the analysis. Median radiotherapy dose was 45 Gy (range, 42-51 Gy) delivered with a median 4 cycles of chemotherapy (range, 2-6). RTOG Grade 3 acute esophagitis developed in 11 patients. No patient developed Grade 4 or 5 esophagitis. Simple logistic regression analyses demonstrated a highly significant association between Grade 3 acute esophagitis and mean esophageal dose (p = 0.002) as well as relative volume dosimetric area under curve (RV-AUC; p = 0.004). Using multiple regression analysis, RV-AUC was identified as the only factor associated with Grade 3 esophagitis (p = 0.004). The most strongly associated dosimetric volume was the V15 (Grade 3 esophagitis rates of 15% vs. 64% for V15 <60% versus {>=}60%, respectively). Conclusions: RV-AUC is the factor most associated with development of Grade 3 acute esophagitis in limited stage SCLC patients receiving BID-CRT.

  19. Going beyond Environmental Programs and Green Practices at the American Library Association

    E-Print Network [OSTI]

    Jankowska, Maria A.

    2011-01-01

    continued? ” (2001). Public Libraries 40 (1): 22-23. 8. ALATechnology (LITA), Public Library Association (PLA), andin collaboration with the Public Library Association

  20. QER - Comment of American Public Power Association 5 | Department of Energy

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematicsEnergyInterested PartiesBuildingBudget || DepartmentPutting Solar Panels toin DesignAmerican

  1. Associations of symptoms related to isocyanate, ureaformol, and formophenolic exposures with respiratory symptoms and lung function in coal miners

    SciTech Connect (OSTI)

    Bertrand, J.P.; Simon, V.; Chau, N.

    2007-04-15

    The respiratory effects of diphenylmethane diisocyanate (MDI)-based resins and ureaformol- and formophenolic-based resins, used in coal mining, are unknown. This cross-sectional study of 354 miners evaluated respiratory health in miners with MDI-related symptoms (IS) and ureaformol/formophenolic-related symptoms (UFS). The protocol included clinical examination, chest radiograph, questionnaire on respiratory symptoms, smoking habit, job history, resin handling, and spirometry. Resin handling concerned 27.7% of the miners. IS affected 5.6%, and 1.4% also after work. UFS affected 22.6%, and 2.3% also after work. Wheezing affected 35.6%; chronic cough, expectoration, or bronchitis about 10%; dyspnea 5.4%; and asthma 2.8%. The miners with UFS had significantly more frequent chronic cough, expectoration, chronic bronchitis, dyspnea, and wheezing, whereas those with IS at and after work had markedly lower FVC, FEV1, MMEF, FEF50% and FEF25%. These findings raise the possibility of deleterious effects of exposures to MDI and ureaformol/ ormophenolic resins on respiratory health and lung function in coal miners during their working life.

  2. General Business American Business Women's Association (ABWA): Founded in 1949 by Hilary A. Bufton Jr., a

    E-Print Network [OSTI]

    that enhance the knowledge, skill and professional growth of its #12;members. The Women in Technology technology and other related career fields. National Business Association: The National Business Association of Information Technology Professionals (AITP) : Offers opportunities for Information Technology (IT) leadership

  3. Tug of War at Air-Water Interface: Understanding Lipid-Nanoparticle and Lipid-Protein Interaction Associated With Lung Surfactants at a Molecular Level

    E-Print Network [OSTI]

    Chakraborty, Aishik

    2015-05-31

    Lung surfactants [LS] are a complex mixture of lipids and proteins that line the air-water interface in the alveoli of the lungs. They lower the work of breathing by reducing the surface tension and also form a line of ...

  4. Douglas M. Chapin, Ph.D., NAE, Fellow, American Nuclear Society is a Principal of MPR Associates, Inc. He holds a B.S. in Electrical

    E-Print Network [OSTI]

    Aydilek, Ahmet

    Douglas M. Chapin, Ph.D., NAE, Fellow, American Nuclear Society is a Principal of MPR Associates.D. in Nuclear Studies in Chemical Engineering and Nuclear Engineering from Princeton University. Dr. Chapin has worked in the nuclear industry since 1962, beginning with four years in the Naval Reactors design group

  5. 54 The American Journal of Human Genetics Volume 79 July 2006 www.ajhg.org Comprehensive Association Testing of Common Mitochondrial

    E-Print Network [OSTI]

    Mootha, Vamsi K.

    , Parkinson disease, Huntington disease, and other diseases; and (c) common missense variants54 The American Journal of Human Genetics Volume 79 July 2006 www.ajhg.org ARTICLE Comprehensive Association Testing of Common Mitochondrial DNA Variation in Metabolic Disease Richa Saxena, Paul I. W. de

  6. Hastie, T., Tibshirani, R. & Buja, A. (1994b), `Flexible discriminant analysis by optimal scoring', Journal of the American Statistical Association 89, 1255--

    E-Print Network [OSTI]

    Hastie, Trevor

    ', Journal of the American Statistical Association 89, 1255-- 1270. Hertz, J., Krogh, A. & Palmer, R. (1991. 1994a). References Becker, R., Chambers, J. & Wilks, A. (1988), The New S Language, WadsworthHastie, T., Tibshirani, R. & Buja, A. (1994b), `Flexible discriminant analysis by optimal scoring

  7. VOL. 37, NO. 5 JOURNAL OF THE AMERICAN WATER RESOURCES ASSOCIATION

    E-Print Network [OSTI]

    Griffin, Ronald

    (see, for example, Amer- ican Water Works Association, 1991). The difference can be substantial (Martin the quantity consumers demand), it affects supply costs. These two "edges" work in opposing directions). Indeed, the much celebrated potential of water marketing (Easter et al., 1998; National Research Council

  8. New York State Geological Association 67th Annual meeting & Eastern Section of the American Association of Petroleum Geologists 26th Annual meeting, Union College, Schenectady, NY, October 13-15, 1995

    E-Print Network [OSTI]

    Kidd, William S. F.

    1 New York State Geological Association 67th Annual meeting & Eastern Section of the American In The New York Capital District W.S.F. Kidd, A. Plesch, and F.W. Vollmer This trip will cover the full width and Structure of the Taconic Flysch, Melange, and Allochthon, in the New York Capital District. pp. 57

  9. Influence of radiation therapy on the lung-tissue in breast cancer patients: CT-assessed density changes and associated symptoms

    SciTech Connect (OSTI)

    Rotstein, S.; Lax, I.; Svane, G. )

    1990-01-01

    The relative electron density of lung tissue was measured from computer tomography (CT) slices in 33 breast cancer patients treated by various techniques of adjuvant radiotherapy. The measurements were made before radiotherapy, 3 months and 9 months after completion of radiation therapy. The changes in lung densities at 3 months and 9 months were compared to radiation induced radiological (CT) findings. In addition, subjective symptoms such as cough and dyspnoea were assessed before and after radiotherapy. It was observed that the mean of the relative electron density of lung tissue varied from 0.25 when the whole lung was considered to 0.17 when only the anterior lateral quarter of the lung was taken into account. In patients with positive radiological (CT) findings the mean lung density of the anterior lateral quarter increased 2.1 times 3 months after radiotherapy and was still increased 1.6 times 6 months later. For those patients without findings, in the CT pictures the corresponding values were 1.2 and 1.1, respectively. The standard deviation of the pixel values within the anterior lateral quarter of the lung increased 3.8 times and 3.2 times at 3 months and 9 months, respectively, in the former group, as opposed to 1.2 and 1.1 in the latter group. Thirteen patients had an increase in either cough or dyspnoea as observed 3 months after completion of radiotherapy. In eleven patients these symptoms persisted 6 months later. No significant correlation was found between radiological findings and subjective symptoms. However, when three different treatment techniques were compared among 29 patients the highest rate of radiological findings was observed in patients in which the largest lung volumes received the target dose. A tendency towards an increased rate of subjective symptoms was also found in this group.

  10. Developed by the Yale Lung Screening and Nodule Program at Yale Cancer Center Smilow Cancer Hospital at Yale-New Haven Copyright 2013, Yale Cancer Center

    E-Print Network [OSTI]

    O'Hern, Corey S.

    Developed by the Yale Lung Screening and Nodule Program at Yale Cancer Center Smilow Cancer Hospital at Yale-New Haven ©Copyright 2013, Yale Cancer Center Summary of Lung Cancer Screening Guidelines Program American Cancer Society (ACS) American Cancer Society. Interim Guidance on Lung Cancer Screening

  11. Advances in Lung Volume

    E-Print Network [OSTI]

    Jones, Michelle

    Advances in Lung Volume Reduction Surgery The Ohio University Medical Center Lung Volume Reduction LungVolumeReductionSurgery Spring 2010 © 2010 The Ohio State University Medical Center ­ 04 Consult Ohio State's #12;The Ohio State University Medical Center Lung Volume Reduction Surgery Patient

  12. AMERICAN STATISTICAL ASSOCIATION

    U.S. Energy Information Administration (EIA) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page| Open Energy Informationmonthly gasoline price to fall to $3.43U.S.longec 188 U.S. Energy1-AllTWOAEP Climate0)9)

  13. AMERICAN STATISTICAL ASSOCIATION

    U.S. Energy Information Administration (EIA) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page| Open Energy Informationmonthly gasoline price to fall to $3.43U.S.longec 188 U.S. Energy1-AllTWOAEP Climate0)9) OPEN

  14. AMERICAN STATISTICAL ASSOCIATION

    U.S. Energy Information Administration (EIA) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page| Open Energy Informationmonthly gasoline price to fall to $3.43U.S.longec 188 U.S. Energy1-AllTWOAEP Climate0)9) OPEN

  15. AMERICAN STATISTICAL ASSOCIATION

    U.S. Energy Information Administration (EIA) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page| Open Energy Informationmonthly gasoline price to fall toUranium Marketing Annual Report

  16. A Heart Health American Indians

    E-Print Network [OSTI]

    Shen, Jun

    Honoring the Gift of Heart Health A Heart Health Educator's Manual for American Indians U . S . D E Health Service Office of Prevention, Education, and Control #12;Honoring the Gift of Heart Health A Heart National Heart, Lung, and Blood Institute and Indian Health Service NIH Publication No. 06-5218 Revised

  17. Bi-plane correlation imaging for improved detection of lung nodules Ehsan Samei1,2,3

    E-Print Network [OSTI]

    Bi-plane correlation imaging for improved detection of lung nodules Ehsan Samei1,2,3 , David M radiography, digital radiography, stereoscopy, lung nodules, lung cancer, computer aided detection (CAD) 1. INTRODUCTION Lung cancer is a leading cause of death in the US, surpassing the mortality associated with breast

  18. STATISTICAL MODELING OF THE LUNG NODULES IN LOW DOSE COMPUTED TOMOGRAPHY SCANS OF THE CHEST

    E-Print Network [OSTI]

    Farag, Aly A.

    the Center for Disease Control (CDC) of the United States reported 90139 men and 69078 women death cases due cancer is the second most common cancer in the United States among white, African American and American]. Research studies to reach an optimal detection rate for early detection of lung cancer, is the hope

  19. The Heparan Sulfate Proteoglycan GPC3 Is a Potential Lung Tumor Suppressor

    E-Print Network [OSTI]

    Tian, Weidong

    The Heparan Sulfate Proteoglycan GPC3 Is a Potential Lung Tumor Suppressor Han Kim,* Guo-Liang Xu University School of Medicine, Boston, Massachusetts Recently, we used gene expression profiling of lung pathways associated with ciga- rette smoking and lung carcinogenesis. The gene encoding Glypican 3

  20. Clinical Investigation: Breast Cancer Predicting the Risk of Secondary Lung Malignancies

    E-Print Network [OSTI]

    Brenner, David Jonathan

    Clinical Investigation: Breast Cancer Predicting the Risk of Secondary Lung Malignancies Associated. Accepted for publication Sep 19, 2011 Summary The risk of secondary lung cancers after whole breast lower risk of secondary lung malignancy than treatment with the supine breast tech- nique. Breast

  1. Decrements in Lung Function Related to Arsenic in Drinking Water in West Bengal, India

    E-Print Network [OSTI]

    California at Berkeley, University of

    Decrements in Lung Function Related to Arsenic in Drinking Water in West Bengal, India Ondine S­2000, the authors investigated relations between lung function, respiratory symptoms, and arsenic in drinking water, consumption of arsenic-contaminated water was associated with respiratory symptoms and reduced lung function

  2. Lung Cancer James Nguyen

    E-Print Network [OSTI]

    Brutlag, Doug

    Lung Cancer James Nguyen Biochemistry 118Q Doug Brutlag A Case Study of Genetics and Environment #12;Lung Cancer · Leading cause of cancer for men and women in United States · Every year, about 164,000 new cases are diagnosed in the US, with an estimated 157,000 deaths. · Leading cause of cancer death

  3. Genetic variants on 15q25.1, smoking and lung cancer: an assessment of mediation and interaction

    E-Print Network [OSTI]

    Lin, Xihong

    1 Genetic variants on 15q25.1, smoking and lung cancer: an assessment of mediation and interaction-wide association studies have identified variants on chromosome 15q25.1 that increase the risk of both lung cancer as to whether the association with lung cancer is direct or mediated by pathways related to smoking behavior

  4. QUESTIONS & ANSWERS ABOUT LUNG CANCER

    E-Print Network [OSTI]

    QUESTIONS & ANSWERS ABOUT LUNG CANCER Q: What are the early signs of lung cancer? How would I know I have it? A: Some of the early warning signs of lung cancer are: · A cough that doesn't go away what may be causing these symptoms. Q: How is lung cancer diagnosed? A: Your doctor may do one or more

  5. Higher Biologically Effective Dose of Radiotherapy Is Associated With Improved Outcomes for Locally Advanced Non-Small Cell Lung Carcinoma Treated With Chemoradiation: An Analysis of the Radiation Therapy Oncology Group

    SciTech Connect (OSTI)

    Machtay, Mitchell; Movsas, Benjamin; Paulus, Rebecca; Gore, Elizabeth M.; Komaki, Ritsuko; Albain, Kathy; Sause, William T.; Curran, Walter J.

    2012-01-01

    Purpose: Patients treated with chemoradiotherapy for locally advanced non-small-cell lung carcinoma (LA-NSCLC) were analyzed for local-regional failure (LRF) and overall survival (OS) with respect to radiotherapy dose intensity. Methods and Materials: This study combined data from seven Radiation Therapy Oncology Group (RTOG) trials in which chemoradiotherapy was used for LA-NSCLC: RTOG 88-08 (chemoradiation arm only), 90-15, 91-06, 92-04, 93-09 (nonoperative arm only), 94-10, and 98-01. The radiotherapeutic biologically effective dose (BED) received by each individual patient was calculated, as was the overall treatment time-adjusted BED (tBED) using standard formulae. Heterogeneity testing was done with chi-squared statistics, and weighted pooled hazard ratio estimates were used. Cox and Fine and Gray's proportional hazard models were used for OS and LRF, respectively, to test the associations between BED and tBED adjusted for other covariates. Results: A total of 1,356 patients were analyzed for BED (1,348 for tBED). The 2-year and 5-year OS rates were 38% and 15%, respectively. The 2-year and 5-year LRF rates were 46% and 52%, respectively. The BED (and tBED) were highly significantly associated with both OS and LRF, with or without adjustment for other covariates on multivariate analysis (p < 0.0001). A 1-Gy BED increase in radiotherapy dose intensity was statistically significantly associated with approximately 4% relative improvement in survival; this is another way of expressing the finding that the pool-adjusted hazard ratio for survival as a function of BED was 0.96. Similarly, a 1-Gy tBED increase in radiotherapy dose intensity was statistically significantly associated with approximately 3% relative improvement in local-regional control; this is another way of expressing the finding that the pool-adjusted hazard ratio as a function of tBED was 0.97. Conclusions: Higher radiotherapy dose intensity is associated with improved local-regional control and survival in the setting of chemoradiotherapy.

  6. Lung pair phantom

    DOE Patents [OSTI]

    Olsen, P.C.; Gordon, N.R.; Simmons, K.L.

    1993-11-30

    The present invention is a material and method of making the material that exhibits improved radiation attenuation simulation of real lungs, i.e., an ``authentic lung tissue`` or ALT phantom. Specifically, the ALT phantom is a two-part polyurethane medium density foam mixed with calcium carbonate, potassium carbonate if needed for K-40 background, lanthanum nitrate, acetone, and a nitrate or chloride form of a radionuclide. This formulation is found to closely match chemical composition and linear attenuation of real lungs. The ALT phantom material is made according to established procedures but without adding foaming agents or preparing thixotropic concentrate and with a modification for ensuring uniformity of density of the ALT phantom that is necessary for accurate simulation. The modification is that the polyurethane chemicals are mixed at a low temperature prior to pouring the polyurethane mixture into the mold.

  7. American Cat Fanciers Association, Inc.

    E-Print Network [OSTI]

    New Hampshire, University of

    ................................................5 Sec 5. Pregnant Cat.....................................................5 Sec 6. Non-Felis Catus

  8. Early Lung Cancer Detection Program

    Broader source: Energy.gov [DOE]

    Since 2000, DOE has made screening for occupational lung cancer with low-dose helical computed tomography (CT) scans available to workers at high risk for lung cancer. Because former workers undertook essential activities to fulfill the Department's mission, many of them were at risk for lung cancer.

  9. Lung cancer risks in the vicinity of uranium tailings sites. [UMTRA Project

    SciTech Connect (OSTI)

    Rogers, V.C.; Sandquist, G.M. (Rogers and Associates Engineering Corp., Salt Lake City, UT (USA))

    1982-04-01

    Lung cancer mortality data have been assembled for many counties of interest to the Uranium Mill Tailings Remedial Action Program (UMTRAP). The counties generally either contain UMTRAP tailings sites or are adjacent to them. The lung cancer rates of nearly all counties are less than the US average rate. In addition, some of the many factors associated with lung cancer are identified as are cancer risk estimators for radon daughters. 17 refs., 19 figs., 1 tab.

  10. CHEST Supplement Screening for Lung Cancer

    E-Print Network [OSTI]

    O'Hern, Corey S.

    e78S CHEST Supplement Screening for Lung Cancer DIAGNOSIS AND MANAGEMENT OF LUNG CANCER, 3RD ED individuals). 3.2.2. In patients at risk for developing lung cancer, screening for lung cancer with sputum are age 55 to 74 and who have smoked for Background: Lung cancer is by far the major cause of cancer

  11. Lung Transplantation for Advanced Bronchiectasis

    E-Print Network [OSTI]

    Turner, Monica G.

    Lung Transplantation for Advanced Bronchiectasis Don Hayes Jr., M.D., F.A.A.P., F.A.C.P., F.C.C.P.1 and Keith C. Meyer, M.D., M.S., F.A.C.P., F.C.C.P.2 ABSTRACT Lung transplant (LT) can be successfully performed on patients with advanced bronchiectatic lung disease with subsequent good posttransplant quality

  12. DEFENSA PERSONAL -GAU LUNG SAT FUNDAMENTACIN

    E-Print Network [OSTI]

    Escolano, Francisco

    DEFENSA PERSONAL - GAU LUNG SAT FUNDAMENTACIÓN El Gau Lung Sat es un programa de entrenamiento cuyo aprendizaje la innovadora metodología del Gau Lung Sat. Esta establece diferentes áreas de trabajo

  13. Residential radon and lung cancer incidence in a Danish cohort

    SciTech Connect (OSTI)

    Braeuner, Elvira V., E-mail: ole@cancer.dk [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark); Danish Building Research Institute, Aalborg University (Denmark); Andersen, Claus E. [Center for Nuclear Technologies, Radiation Research Division, Riso National Laboratory for Sustainable Energy, Technical University of Denmark, Roskilde (Denmark)] [Center for Nuclear Technologies, Radiation Research Division, Riso National Laboratory for Sustainable Energy, Technical University of Denmark, Roskilde (Denmark); Sorensen, Mette [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark)] [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark); Jovanovic Andersen, Zorana [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark) [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark); Center for Epidemiology Screening, Department of Public Health, University of Copenhagen (Denmark); Gravesen, Peter [Geological Survey of Denmark and Greenland, Copenhagen (Denmark)] [Geological Survey of Denmark and Greenland, Copenhagen (Denmark); Ulbak, Kaare [National Institute of Radiation Protection, Herlev (Denmark)] [National Institute of Radiation Protection, Herlev (Denmark); Hertel, Ole [Department of Environmental Science, Aarhus University, Aarhus (Denmark)] [Department of Environmental Science, Aarhus University, Aarhus (Denmark); Pedersen, Camilla [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark)] [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark); Overvad, Kim [Department of Epidemiology, School of Public Health, Aarhus University, Aarhus (Denmark)] [Department of Epidemiology, School of Public Health, Aarhus University, Aarhus (Denmark); Tjonneland, Anne; Raaschou-Nielsen, Ole [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark)] [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark)

    2012-10-15

    High-level occupational radon exposure is an established risk factor for lung cancer. We assessed the long-term association between residential radon and lung cancer risk using a prospective Danish cohort using 57,053 persons recruited during 1993-1997. We followed each cohort member for cancer occurrence until 27 June 2006, identifying 589 lung cancer cases. We traced residential addresses from 1 January 1971 until 27 June 2006 and calculated radon at each of these addresses using information from central databases regarding geology and house construction. Cox proportional hazards models were used to estimate incidence rate ratios (IRR) and 95% confidence intervals (CI) for lung cancer risk associated with residential radon exposure with and without adjustment for sex, smoking variables, education, socio-economic status, occupation, body mass index, air pollution and consumption of fruit and alcohol. Potential effect modification by sex, traffic-related air pollution and environmental tobacco smoke was assessed. Median estimated radon was 35.8 Bq/m{sup 3}. The adjusted IRR for lung cancer was 1.04 (95% CI: 0.69-1.56) in association with a 100 Bq/m{sup 3} higher radon concentration and 1.67 (95% CI: 0.69-4.04) among non-smokers. We found no evidence of effect modification. We find a positive association between radon and lung cancer risk consistent with previous studies but the role of chance cannot be excluded as these associations were not statistically significant. Our results provide valuable information at the low-level radon dose range.

  14. H-1 Nuclear Magnetic Resonance Metabolomics Analysis Identifies Novel Urinary Biomarkers for Lung Function

    SciTech Connect (OSTI)

    MCClay, Joseph L.; Adkins, Daniel E.; Isern, Nancy G.; O'Connell, Thomas M.; Wooten, Jan B.; Zedler, Barbara K.; Dasika, Madhukar S.; Webb, B. T.; Webb-Robertson, Bobbie-Jo M.; Pounds, Joel G.; Murrelle, Edward L.; Leppert, Mark F.; van den Oord, Edwin J.

    2010-06-04

    Chronic obstructive pulmonary disease (COPD), characterized by chronic airflow limitation, is a serious and growing public health concern. The major environmental risk factor for COPD is tobacco smoking, but the biological mechanisms underlying COPD are not well understood. In this study, we used proton nuclear magnetic resonance (1H-NMR) spectroscopy to identify and quantify metabolites associated with lung function in COPD. Plasma and urine were collected from 197 adults with COPD and from 195 adults without COPD. Samples were assayed using a 600 MHz NMR spectrometer, and the resulting spectra were analyzed against quantitative spirometric measures of lung function. After correcting for false discoveries and adjusting for covariates (sex, age, smoking) several spectral regions in urine were found to be significantly associated with baseline lung function. These regions correspond to the metabolites trigonelline, hippurate and formate. Concentrations of each metabolite, standardized to urinary creatinine, were associated with baseline lung function (minimum p-value = 0.0002 for trigonelline). No significant associations were found with plasma metabolites. Two of the three urinary metabolites positively associated with baseline lung function, i.e. hippurate and formate, are often related to gut microflora. This suggests that the microbiome composition is variable between individuals with different lung function. Alternatively, the nature and origins of all three associated metabolites may reflect lifestyle differences affecting overall health. Our results will require replication and validation, but demonstrate the utility of NMR metabolomics as a screening tool for identifying novel biomarkers of lung disease or disease risk.

  15. DRAFT of Klahr, D. (2012) Patterns, Rules, & Discoveries in Life and in Science. In Carver, S., & Shrager, J..(Eds.) The Journey From Child to Scientist: Integrating Cognitive Development and the Education Sciences. Washington DC: American Psychological A

    E-Print Network [OSTI]

    Klahr, David

    2012-01-01

    Development and the Education Sciences. Washington DC: American Psychological Association 2 ingenious and the Education Sciences. Washington DC: American Psychological Association 1 Patterns, Rules, & Discoveries

  16. Peptide targeting and imaging of damaged lung tissue in influenza-infected mice

    E-Print Network [OSTI]

    Li, Na

    In this study, we investigate whether pH (low) insertion peptide (pHLIP) can target regions of lung injury associated with influenza infection. Materials & methods: Fluorophore-conjugated pHLIP was injected intraperitoneally ...

  17. www.yalecancercenter.org Lung Cancer Screening

    E-Print Network [OSTI]

    O'Hern, Corey S.

    www.yalecancercenter.org Lung Cancer Screening Guest Experts: Lynn Tanoue, MD Professor of Therapeutic Radiology and an expert in the use of radiation to treat lung cancers and cutaneous lymphomas Oncology Program. Dr. Detterbeck and I also co- direct the new Yale Lung Cancer and Lung Nodule Screening

  18. Superthreshold Behavior of Ultrasound-Induced Lung

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Superthreshold Behavior of Ultrasound-Induced Lung Hemorrhage in Adult Rats Role of Pulse of an earlier ultrasound-induced lung hemorrhage study (Ultrasound Med Biol 2003; 29:1625­1634) that estimated, at least for the lung. Key Words: duty factor; lung hemorrhage; pulsed ultrasound; pulse duration; pulse

  19. Automated segmentation of lungs with severe interstitial lung disease in CT

    E-Print Network [OSTI]

    Automated segmentation of lungs with severe interstitial lung disease in CT Jiahui Wang Department: Accurate segmentation of lungs with severe interstitial lung disease ILD in thoracic computed tomography CT developed in this study a texture analysis-based method for accurate segmentation of lungs with severe ILD

  20. Lung injury, inflammation and Akt signaling following inhalation of particulate hexavalent chromium

    SciTech Connect (OSTI)

    Beaver, Laura M. [Department of Pharmacology and Physiology, George Washington University Medical Center, 2300 I Street NW, Washington, DC 20037 (United States); Institute of Biomedical Sciences, George Washington University Medical Center, 2300 I Street NW, Washington, DC 20037 (United States); Stemmy, Erik J.; Constant, Stephanie L. [Institute of Biomedical Sciences, George Washington University Medical Center, 2300 I Street NW, Washington, DC 20037 (United States); Department of Microbiology, Immunology and Tropical Medicine, George Washington University Medical Center, 2300 I Street NW, Washington, DC 20037 (United States); Schwartz, Arnold [Department of Pathology, George Washington University Medical Center, 2300 I Street NW, Washington, DC 20037 (United States); Little, Laura G. [University of Montana, Department of Chemistry, 32 Campus Drive, Missoula, MT 59812 (United States); Gigley, Jason P. [Department of Microbiology, Immunology and Tropical Medicine, George Washington University Medical Center, 2300 I Street NW, Washington, DC 20037 (United States); Chun, Gina [Department of Pharmacology and Physiology, George Washington University Medical Center, 2300 I Street NW, Washington, DC 20037 (United States); Institute of Biomedical Sciences, George Washington University Medical Center, 2300 I Street NW, Washington, DC 20037 (United States); Sugden, Kent D. [University of Montana, Department of Chemistry, 32 Campus Drive, Missoula, MT 59812 (United States)] (and others)

    2009-02-15

    Certain particulate hexavalent chromium [Cr(VI)] compounds are human respiratory carcinogens that release genotoxic soluble chromate, and are associated with fibrosis, fibrosarcomas, adenocarcinomas and squamous cell carcinomas of the lung. We postulate that inflammatory processes and mediators may contribute to the etiology of Cr(VI) carcinogenesis, however the immediate (0-24 h) pathologic injury and immune responses after exposure to particulate chromates have not been adequately investigated. Our aim was to determine the nature of the lung injury, inflammatory response, and survival signaling responses following intranasal exposure of BALB/c mice to particulate basic zinc chromate. Factors associated with lung injury, inflammation and survival signaling were measured in airway lavage fluid and in lung tissue. A single chromate exposure induced an acute immune response in the lung, characterized by a rapid and significant increase in IL-6 and GRO-{alpha} levels, an influx of neutrophils, and a decline in macrophages in lung airways. Histological examination of lung tissue in animals challenged with a single chromate exposure revealed an increase in bronchiolar cell apoptosis and mucosal injury. Furthermore, chromate exposure induced injury and inflammation that progressed to alveolar and interstitial pneumonitis. Finally, a single Cr(VI) challenge resulted in a rapid and persistent increase in the number of airways immunoreactive for phosphorylation of the survival signaling protein Akt, on serine 473. These data illustrate that chromate induces both survival signaling and an inflammatory response in the lung, which we postulate may contribute to early oncogenesis.

  1. Development of a microfluidic device for blood oxygenation by photocatalysis

    E-Print Network [OSTI]

    Ullah, Tania

    2009-01-01

    Recent statistics provided by the American Lung Association assert that over 400,000 Americans die every year from lung disorders and more than 35 million are now living with symptoms of lung disease. Mortality rates of ...

  2. Journal of Heredity 2003:94(4):341351 2003 The American Genetic Association DOI: 10.1093/jhered/esg061

    E-Print Network [OSTI]

    Volis, Sergei

    of variation was ambiguous. Although two alleles exhibited a pattern of distribution that cannot be explained examining the association of genetic variation with discrete environmental heterogeneity (soil type, sun.g., rainfall, temperature, or salinity) (Hedrick et al. 1976). This methodology is explicit in tests

  3. Ohio State adds 18 new AAAS fellows Eighteen Ohio State faculty were elected among the newest class of Fellows of the American Association for the

    E-Print Network [OSTI]

    ) to test and expand a university-developed technology that can produce biogas from solid organic wastes and bioenergy crops, such as yard waste, crop residue, and lignocellulosic food waste. The integrated anaerobic digestion system (iADs), a patent-pending technology developed by Yebo Li, associate professor of food

  4. Comprehensive molecular profiling of lung adenocarcinoma

    E-Print Network [OSTI]

    Lander, Eric S.

    Adenocarcinoma of the lung is the leading cause of cancer death worldwide. Here we report molecular profiling of 230 resected lung adenocarcinomas using messenger RNA, microRNA and DNA sequencing integrated with copy number, ...

  5. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Bandettini, Peter A.

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : What You Need To Know About High on lowering cholesterol is available from the National Heart, Lung, and Blood Institute (NHLBI) Web site

  6. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Bandettini, Peter A.

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : Coronary Heart Disease C oronary is available from the National Heart, Lung, and Blood Institute (NHLBI) Web site at www.nhlbi.nih.gov (under

  7. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Bandettini, Peter A.

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : Physical Activity and Your Heart benefits. It can strengthen your heart and improve lung func- tion, and it may help prevent certain types

  8. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Shen, Jun

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : Atherosclerosis A therosclerosis, Lung, and Blood Institute (NHLBI) Web site at www.nhlbi.nih.gov (under Health Information

  9. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Shen, Jun

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : Facts About Healthy Weight Why indicator of your risk for a variety of diseases. To check your BMI, use the National Heart, Lung, and Blood

  10. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Shen, Jun

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : Healthy Sleep S leep is not just information on healthy sleep and sleep disorders is available from the National Heart, Lung, and Blood

  11. LungCAD: A Clinically Approved, Machine Learning System for Lung Cancer Detection

    E-Print Network [OSTI]

    Chandy, John A.

    LungCAD: A Clinically Approved, Machine Learning System for Lung Cancer Detection R Bharat Rao Street, New York, NY 10016 ABSTRACT We present LungCAD, a computer aided diagnosis (CAD) system system be tested in a clini- cal trial. We describe the clinical trial in which LungCAD was tested

  12. VOLUME 87, NUMBER 8 P H Y S I C A L R E V I E W L E T T E R S 20 AUGUST 2001 Avalanche Dynamics of Crackle Sound in the Lung

    E-Print Network [OSTI]

    Alencar, Adriano Mesquita

    of Crackle Sound in the Lung Adriano M. Alencar,1,2 Sergey V. Buldyrev,2 Arnab Majumdar,2 H. Eugene Stanley,2, called "crackles," which are associated with explosive openings of airways during lung inflation-field solution of the model which provides information about lung inflation. DOI: 10.1103/PhysRevLett.87

  13. Radiofrequency Ablation of Subpleural Lung Malignancy: Reduced Pain Using an Artificially Created Pneumothorax

    SciTech Connect (OSTI)

    Lee, Edward W., E-mail: EdwardLee@mednet.ucla.edu; Suh, Robert D., E-mail: rsuh@mednet.ucla.ed [David Geffen School of Medicine at UCLA, Department of Radiological Sciences, Thoracic Imaging and Intervention, Center for the Health Sciences (CHS), UCLA Medical Center (United States); Zeidler, Michelle R. [David Geffen School of Medicine at UCLA, Department of Internal Medicine, Pulmonary and Critical Care (United States); Tsai, Irene S. [David Geffen School of Medicine at UCLA, Department of Radiological Sciences, Thoracic Imaging and Intervention, Center for the Health Sciences (CHS), UCLA Medical Center (United States); Cameron, Robert B. [David Geffen School of Medicine at UCLA, Department of Surgery, Thoracic Oncology (United States); Abtin, Fereidoun G.; Goldin, Jonathan G. [David Geffen School of Medicine at UCLA, Department of Radiological Sciences, Thoracic Imaging and Intervention, Center for the Health Sciences (CHS), UCLA Medical Center (United States)

    2009-07-15

    One of the main issues with radiofrequency (RF) ablation of the subpleural lung malignancy is pain management during and after RF ablation. In this article, we present a case that utilized a technique to decrease the pain associated with RF ablation of a malignancy located within the subpleural lung. Under CT guidance, we created an artificial pneumothorax prior to the RF ablation, which resulted in minimizing the pain usually experienced during and after the procedure. It also decreased the amount of pain medications usually used in patients undergoing RF ablation of a subpleural lung lesion.

  14. Biomarker for Lung and Inflammatory Diseases

    E-Print Network [OSTI]

    Heydari, Payam

    Biomarker for Lung and Inflammatory Diseases Tech ID: 23381 / UC Case 2012-660-0 BACKGROUND and clinical research. We describe herein a novel biomarker and method of detecting interstitial lung disease have discovered that patients with interstitial lung and intestinal inflammatory diseases, for example

  15. www.yalecancercenter.org Lung Cancer Awareness

    E-Print Network [OSTI]

    O'Hern, Corey S.

    www.yalecancercenter.org Lung Cancer Awareness Month Update Guest Expert: Frank Detterbeck, MD take a look at the prevention and treatment of lung cancer with Dr. Frank Detterbeck, Professor I want to start out with a question about cigarette smoking and lung cancer. Obviously

  16. www.yalecancercenter.org Lung Cancer Awareness

    E-Print Network [OSTI]

    O'Hern, Corey S.

    www.yalecancercenter.org Lung Cancer Awareness Month Update 2008 Guest Expert: Frank Detterbeck, MD reach the end of lung cancer awareness month, Ed and Ken welcome the Directors of the Yale Cancer Center of thoracic surgery at Yale and Dr. Tanoue is a Professor of pulmonary medicine. Tanoue Unfortunately, lung

  17. www.yalecancercenter.org Understanding Lung Cancer

    E-Print Network [OSTI]

    O'Hern, Corey S.

    www.yalecancercenter.org Understanding Lung Cancer Guest Expert: Daniel Morgensztern, MD www of radiation to treat lung cancer and cutaneous lymphomas. If you would like to join the conversation, you can at the Yale School of Medicine and he specializes in the treatment and care of patients with lung cancer. Here

  18. Superthreshold Behavior of Ultrasound-Induced Lung

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Superthreshold Behavior of Ultrasound-Induced Lung Hemorrhage in Adult Rats Role of Pulse and reevaluate the ultra- sound-induced lung hemorrhage findings of a previous 5 × 3 factorial design study, 250, and 500 Hz) and exposure duration (ED; 5, 10, and 20 s) on ultrasound-induced lung hemorrhage

  19. What Lung Cancer Patients Need to Know

    E-Print Network [OSTI]

    Kaski, Samuel

    What Lung Cancer Patients Need to Know About Bone Health A Publication of The Bone and Cancer Foundation #12;Contents THIS PUBLICATION PROVIDES IMPORTANT INFORMATION ABOUT THE RELATIONSHIP BETWEEN LUNG CANCER AND BONE HEALTH. HOW BONE WORKS (PAGE 2). WHAT LUNG CANCER CAN DO TO BONE (PAGE 2). TREATING BONE

  20. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Bandettini, Peter A.

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : Asthma A sthma is a chronic (longterm) lung dis ease that inflames and narrows the air ways. This makes the airways swollen and very, the muscles around them tighten. This causes the airways to nar row, and less air flows to your lungs

  1. Clinical and experimental pathology of lung cancer

    SciTech Connect (OSTI)

    McVie, J.G.; Bakker, W.; Wagenaar, S.C.; Carney, D.

    1986-01-01

    This book contains 17 selections. Some of the titles are: Flow cytometric DNA analysis in the study of small cell carcinoma of the lung; Mechanisms of oncogenesis; Adhesion mechanisms in liver metastasis; Current concepts in the therapy of small cell lung cancer; Application of monoclonal antibodies in imaging and therapy; and Clinical applications of the biologic properties of small cell lung cancer.

  2. The branching programme of mouse lung development

    E-Print Network [OSTI]

    Krasnow, Mark A.

    ARTICLES The branching programme of mouse lung development Ross J. Metzger1 {, Ophir D. Klein2 {, Gail R. Martin2 & Mark A. Krasnow1 Mammalian lungs are branched networks containing thousands by three geometrically simple local modes of branching used in three different orders throughout the lung

  3. Therapeutic strategies to overcome crizotinib resistance in non-small cell lung cancers harboring the fusion oncogene EML4-ALK

    E-Print Network [OSTI]

    Katayama, Ryohei

    The echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) fusion oncogene represents a molecular target in a small subset of non-small cell lung cancers (NSCLCs). This fusion leads to ...

  4. Raquel Meyer Alexander Associate Professor

    E-Print Network [OSTI]

    Marsh, David

    . 2011. U.S. Congressional testimony from KU student about tax research service-learning class project.ku.edu/~katrina Used by the American Bar Association to provide tax assistance to victims. 2005. Cited in testimony

  5. Thursday, April 10, 2008 A Fuller Picture of Your Lungs

    E-Print Network [OSTI]

    Walsworth, Ronald L.

    Thursday, April 10, 2008 A Fuller Picture of Your Lungs A cheap MRI machine images lung function poor pictures of the lungs, which are full of air, and gives an incomplete picture of lung functions a cheap MRI machine that uses a weak magnetic field to image critical aspects of lung physiology

  6. QER- Comment of American Gas Association 2

    Broader source: Energy.gov [DOE]

    Attached please find AGA's comments relating to critical issues facing the natural gas distribution industry, which we believe could be usefully addressed in the first phase of the DOE Quadrennial Energy Review (QER). Our comments as submitted here consist of a cover letter and four additional attachments. My colleague Pam Lacey has previously submitted AGA's comments relating to methane emissions under separate cover.

  7. Moore honored with American Statistical Association award

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    impact. Moore is a Fellow of the Royal Statistical Society. Her awards include Certified Six Sigma Master Black Belt, Laboratory Distinguished Performance Team Award, and a...

  8. QER- Comment of American Gas Association 1

    Broader source: Energy.gov [DOE]

    Attached please find AGA's comments on methane emissions issues in the first phase of the DOE Quadrennial Energy Review (QER), consisting of a cover letter and attachments. Dr. Kathryn Clay will be submitting AGA's comments on other aspects of the QER. Please let me know if you have any questions.

  9. QER- Comment of American Gas Association 4

    Broader source: Energy.gov [DOE]

    From: Peterson, Christopher (EIA)Sent: Tuesday, October 14, 2014 12:11 PMTo: Pierpoint, LaraSubject: FW: AGA comments to QER: Natural Gas Emissions Section

  10. WAYNE STATE UNIVERSITY AMERICAN ASSOCIATION OF

    E-Print Network [OSTI]

    Berdichevsky, Victor

    /No Lockout ..................................................................... 13 Article X: Layoff

  11. QER- Comment of American Gas Association 3

    Office of Energy Efficiency and Renewable Energy (EERE)

    Dear Ms. Pickett: Attached please find AGA's comments on natural gas vehicle fueling infrastructure as part of our response to the first phase of the DOE Quadrennial Energy Review (QER), consisting of a cover letter and attachments. Respectfully submitted, Kathryn Clay

  12. Terwilliger named American Crystallographic Association Fellow

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservationBio-Inspired Solar FuelTechnologyTel: Name: Rm. Tel:

  13. Comprehensive genomic characterization of squamous cell lung cancers

    E-Print Network [OSTI]

    Lander, Eric S.

    Lung squamous cell carcinoma is a common type of lung cancer, causing approximately 400,000 deaths per year worldwide. Genomic alterations in squamous cell lung cancers have not been comprehensively characterized, and no ...

  14. Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

    E-Print Network [OSTI]

    Lander, Eric S.

    Lung adenocarcinoma, the most common subtype of non-small cell lung cancer, is responsible for more than 500,000 deaths per year worldwide. Here, we report exome and genome sequences of 183 lung adenocarcinoma tumor/normal ...

  15. Biomechanics of the Lung 1 HUMAN RESPIRATORY MECHANICS, part 1

    E-Print Network [OSTI]

    Prestwich, Ken

    Biomechanics of the Lung 1 HUMAN RESPIRATORY MECHANICS, part 1: THE BIOMECHANICS OF THE LUNG1 Summary: We begin a detailed study of ventilation and then examine the static forces that exist in lungs at different volumes

  16. Honda: North American Manufacturing Facilities | Department of...

    Office of Environmental Management (EM)

    Honda: North American Manufacturing Facilities Honda: North American Manufacturing Facilities From October, 2008 Honda: North American Manufacturing Facilities More Documents &...

  17. Diesel Exhaust Dispersion in a Phospholipid Lung Surfactant ...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Exhaust Dispersion in a Phospholipid Lung Surfactant Diesel Exhaust Dispersion in a Phospholipid Lung Surfactant 2005 Diesel Engine Emissions Reduction (DEER) Conference...

  18. Software Architecture Decomposition Using Attributes Chung-Horng Lung

    E-Print Network [OSTI]

    Lung, Chung-Horng

    1 Software Architecture Decomposition Using Attributes Chung-Horng Lung Xia Xu Department and Eppinger [29] in other engineering disciplines. Inspired by Alexander, Andreu [2] and Lung,

  19. Automatic Lung Vessel Segmentation via Stacked Multiscale Feature Learning

    E-Print Network [OSTI]

    Toronto, University of

    Automatic Lung Vessel Segmentation via Stacked Multiscale Feature Learning Ryan Kiros, Karteek We introduce a representation learning approach to segmenting vessels in the lungs. Our algorithm

  20. Involvement of growth factors and their receptors in radon-induced rat lung tumors

    SciTech Connect (OSTI)

    Leung, F.C.; Dagle, G.E.; Cross, F.T. [Pacific Northwest Lab., Richland, WA (United States)

    1992-12-31

    In this paper we examine the role of growth factors (GF) and their receptors (GFR) in radon-induced rat lung tumors. Inhalation exposure of radon and its daughters induced lung tumors in rats, but the molecule/cellular mechanisms are not known. Recent evidence suggests that GF/GFR play a critical role in the growth and development of lung cancer in humans and animals. We have developed immunocytochemical methods for identifying sites of production and action of GF/GFR at the cellular level; for example, the avidin-biotin horseradish peroxidase technique. In radon-induced rat epidermoid carcinomas, epidermal growth factor (EGF), EGF-receptors (EGF-R), transforming growth factor alpha (TGF-{alpha}), and bombesin were found to be abnormally expressed. These abnormal expressions, mainly associated with epidermoid carcinomas of the lung, were not found in any other lung tumor types. Our data suggest that EGF, EGF-R, TGF-{alpha}, and bombesin are involved in radon oncogenesis in rat lungs, especially in epidermoid carcinomas, possibly through the autocrine/paracrine pathway.

  1. Molecular Markers of Lung Cancer in MAYAK Workers

    SciTech Connect (OSTI)

    Steven A. Belinsky, PhD

    2007-02-15

    The molecular mechanisms that result in the elevated risk for lung cancer associated with exposure to radiation have not been well characterized. Workers from the MAYAK nuclear enterprise are an ideal cohort in which to study the molecular epidemiology of cancer associated with radiation exposure and to identify the genes targeted for inactivation that in turn affect individual risk for radiation-induced lung cancer. Epidemiology studies of the MAYAK cohort indicate a significantly higher frequency for adenocarcinoma and squamous cell carcinoma (SCC) in workers than in a control population and a strong correlation between these tumor types and plutonium exposure. Two hypotheses will be evaluated through the proposed studies. First, radiation exposure targets specific genes for inactivation by promoter methylation. This hypothesis is supported by our recent studies with the MAYAK population that demonstrated the targeting of the p16 gene for inactivation by promoter methylation in adenocarcinomas from workers (1). Second, genes inactivated in tumors can serve as biomarkers for lung cancer risk in a cancer-free population of workers exposed to plutonium. Support for this hypothesis is based on exciting preliminary results of our nested, case-control study of persons from the Colorado cohort. In that study, a panel of methylation markers for predicting lung cancer risk is being evaluated in sputum samples from incident lung cancer cases and controls. The first hypothesis will be tested by determining the prevalence for promoter hypermethylation of a panel of genes shown to play a critical role in the development of either adenocarcinoma and/or SCC associated with tobacco. Our initial studies on adenocarcinoma in MAYAK workers will be extended to evaluate methylation of the PAX5 {alpha}, PAX5 {beta}, H-cadherin, GATA5, and bone morphogenesis 3B (BMP3B) genes in the original sample set described under Preliminary studies. In addition, studies will be initiated in SCC from workers and controls to identify genes targeted for inactivation by plutonium in this other common histologic form of lung cancer. We will examine methylation of the p16, O{sup 6}-methylguanine-DNA methyl-transferase (MGMT), and death associated protein kinase genes ([DAP-K], evaluated previously in adenocarcinomas) as well as the new genes being assessed in the adenocarcinomas. The second hypothesis will be tested in a cross-sectional study of cancer-free workers exposed to plutonium and an unexposed population. A cohort of 700 cancer-free workers and 700 unexposed persons is being assembled, exposures are being defined, and induced sputum collected at initial entry into the study and approximately 1-year later. Exposed and unexposed persons will be matched by 5-year age intervals and smoking status (current and former). The frequency for methylation of four genes that show the greatest difference in prevalence in tumors from workers and controls will be determined in exfoliated cells within sputum. These studies will extend those in primary tumors to determine whether difference in prevalence for individual or multiple genes are detected in sputum samples from high-risk subjects exposed to plutonium. Follow-up of this cohort offers the opportunity to validate these endpoints and future biomarkers as true markers for lung cancer risk.

  2. A poroelastic model of the lung

    E-Print Network [OSTI]

    Berger, Lorenz; Burrowes, Kelly; Grau, Vicente; Tavener, Simon; Bordas, Rafel

    2014-01-01

    This work is motivated by the modelling of ventilation and deformation in the lung for understanding the biomechanics of respiratory diseases. The main contribution is the derivation and implementation of a lung model that tightly couples a poroelastic model of lung parenchyma to an airway fluid network. The poroelastic model approximates the porous structure of lung parenchyma using a continuum model that allows us to naturally model changes in physiology by spatially varying material parameters, whilst conserving mass and momentum within the tissue. The proposed model will also take advantage of realistic deformation boundary conditions obtained from image registration, to drive the simulation. A finite element method is presented to discretize the equations in a monolithic way to ensure convergence of the nonlinear problem. To demonstrate the coupling between the poroelastic medium and the network flow model numerical simulations on a realistic lung geometry are presented. These numerical simulations are a...

  3. Functional and inflammatory alterations in the lung following exposure of rats to nitrogen mustard

    SciTech Connect (OSTI)

    Sunil, Vasanthi R., E-mail: sunilvr@eohsi.rutgers.edu [Department of Pharmacology and Toxicology, Rutgers University, Piscataway, NJ (United States); Patel, Kinal J., E-mail: kinalv5@gmail.com [Department of Pharmacology and Toxicology, Rutgers University, Piscataway, NJ (United States); Shen, Jianliang, E-mail: jianliangs@gmail.com [Department of Pharmacology and Toxicology, Rutgers University, Piscataway, NJ (United States); Reimer, David, E-mail: reimerd@las.rutgers.edu [Laboratory Animal Services, Rutgers University, Piscataway, NJ (United States); Gow, Andrew J., E-mail: gow@rci.rutgers.edu [Department of Pharmacology and Toxicology, Rutgers University, Piscataway, NJ (United States); Laskin, Jeffrey D., E-mail: jlaskin@eohsi.rutgers.edu [Department of Environmental and Occupational Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, NJ (United States); Laskin, Debra L., E-mail: laskin@eohsi.rutgers.edu [Department of Pharmacology and Toxicology, Rutgers University, Piscataway, NJ (United States)

    2011-01-01

    Nitrogen mustard is a vesicant that causes damage to the respiratory tract. In these studies, we characterized the acute effects of nitrogen mustard on lung structure, inflammatory mediator expression, and pulmonary function, with the goal of identifying mediators potentially involved in toxicity. Treatment of rats (male Wistar, 200-225 g) with nitrogen mustard (mechlorethamine hydrochloride, i.t., 0.25 mg/kg) resulted in marked histological changes in the respiratory tract, including necrotizing bronchiolitis, thickening of alveolar septa, and inflammation which was evident within 24 h. This was associated with increases in bronchoalveolar lavage protein and cells, confirming injury to alveolar epithelial regions of the lung. Nitrogen mustard administration also resulted in increased expression of inducible nitric oxide synthase and cyclooxygenase-2, pro-inflammatory proteins implicated in lung injury, in alveolar macrophages and alveolar and bronchial epithelial cells. Expression of connective tissue growth factor and matrix metalloproteinase-9, mediators regulating extracellular matrix turnover was also increased, suggesting that pathways leading to chronic lung disease are initiated early in the pathogenic process. Following nitrogen mustard exposure, alterations in lung mechanics and function were also observed. These included decreases in baseline static compliance, end-tidal volume and airway resistance, and a pronounced loss of methacholine responsiveness in resistance, tissue damping and elastance. Taken together, these data demonstrate that nitrogen mustard induces rapid structural and inflammatory changes in the lung which are associated with altered lung functioning. Understanding the nature of the injury induced by nitrogen mustard and related analogs may aid in the development of efficacious therapies for treatment of pulmonary injury resulting from exposure to vesicants.

  4. QER- Comment of American Hydrogen Northeast, Inc.

    Office of Energy Efficiency and Renewable Energy (EERE)

    Dear Sir or Madam, Attached please find the Hydrogen Association and the American Hydrogen Northeast,inc's Comments on the first round of QER review. I wish to thank Secretary Moniz and Senator Reed for attending the Providence hearing and providing this opportunity to submit these comments.

  5. Parenteral Hydrocarbon Injection and Associated Toxicities: Two Case Reports

    E-Print Network [OSTI]

    Nelson, Michael E.; Nasr, Isam

    2013-01-01

    Annual Report of the American Association of Poison ControlCenters’ National Poison Data System (NPDS): 29 th AnnualToxikon Consortium, Illinois Poison Control Center, Chicago,

  6. Research results on biomagnetic imaging of the lung tumors Laurel O. Silleruda,b

    E-Print Network [OSTI]

    Coutsias, Evangelos

    of the leading causes of cancer-related death in the United States. One of the difficulties associated that the death rate for lung cancer is so high is a reflection of the suboptimal state of current therapeutic of initial diagnosis 5-year cure rates are ~50% 1 . For patients with more-advanced, nonresectable initial

  7. Aging in American Convents

    E-Print Network [OSTI]

    Corwin, Anna I.

    2009-01-01

    Schuster. Snowdon, David 2001 Aging with Grace: What the Nunreligion, devotion, and aging. CSW JAN09 update tocAging in American Convents FIELDWORK REPORT by Anna I.

  8. Precedents in African American architecture

    E-Print Network [OSTI]

    Sass, Lawrence

    1994-01-01

    As a sub-sets of American culture, African Americans have not been able to offer culturally specific architectural elements to the design process because the history of African American form and space has not been recognized ...

  9. American Institute of Aeronautics Astronautics

    E-Print Network [OSTI]

    American Institute of Aeronautics Astronautics Study Cylindrical Thruster Low Power Space scaling of magnetic circuit leaves almost no magnetic Copyright American Institute Aeronautics; American Institute of Aeronautics Astronautics ability coaxial thrusters achieve performance moderate power

  10. www.yalecancercenter.org Lung Cancer Awareness 2009

    E-Print Network [OSTI]

    O'Hern, Corey S.

    www.yalecancercenter.org Lung Cancer Awareness 2009 Guest Expert: Thomas Lynch, Jr., MD Director of lung cancer. Chu What got you interested in focusing your career on the treatment of lung cancer? Lynch I actually got into lung cancer sort of by serendipity. I wish I could tell you that it was a well

  11. www.yalecancercenter.org A Survivor's Perspective: Lung

    E-Print Network [OSTI]

    O'Hern, Corey S.

    www.yalecancercenter.org A Survivor's Perspective: Lung Cancer Guest Expert: Janet Brown www lung cancers and cutaneous lymphomas. If you would like to join the conversation, you can contact adenocarcinoma lung cancer. It started in my right lung and spread to 3 spots on my spine and to the pons area

  12. Study for Advanced Lung Cancer Patients Guest Expert

    E-Print Network [OSTI]

    O'Hern, Corey S.

    Study for Advanced Lung Cancer Patients Guest Expert: Roy S. Herbst, MD, PhD Ensign Professor message at 888-234-4YCC. This week you will hear a conversation about clinical trials for advanced lung of lung caner at Yale Cancer Center and Smilow Cancer Hospital? Herbst As you probably know, lung cancer

  13. www.yalecancercenter.org An Update on Lung Cancer

    E-Print Network [OSTI]

    O'Hern, Corey S.

    www.yalecancercenter.org An Update on Lung Cancer Guest Expert: Roy Decker, MD, PhD Assistant the detection and treatment of lung cancer with Dr. Scott Gettinger and Dr. Roy Decker. Chu Scott, let us start off by telling our listeners what lung cancer is and how common it is. Gettinger Lung cancer

  14. Immune Reactions of the Lung in Infection and Allergy

    E-Print Network [OSTI]

    Manstein, Dietmar J.

    Immune Reactions of the Lung in Infection and Allergy ¡ Interactions of microorganisms with cells of the lung ¡ Cells and mediators in immune reactions of the lung Sabine Ehrt, New York, USA Rees Kassen, Hannover Characterization of pulmonary host defense mechanisms in chronic lung disease 10.00 ­ 10.40 Albert

  15. Virtual Lung Project Animated Film Series The Challenge

    E-Print Network [OSTI]

    Whitton, Mary C.

    Virtual Lung Project Animated Film Series The Challenge This film series seeks to educate lung. Each video describes a process the lung undergoes to function properly. Through integration of 3D of the lung's functions and purposes. Because mucus flow and ciliary movement are groundbreaking research

  16. NHLBI Workshop Summaries Resident Cellular Components of the Human Lung

    E-Print Network [OSTI]

    Engelhardt, John F.

    NHLBI Workshop Summaries Resident Cellular Components of the Human Lung Current Knowledge and Goals, Maryland; 5 Lung Diseases, National Heart, Lung and Blood Institute, National Institutes of Health and Cell Biology, The University of Iowa, Iowa City, Iowa; 11 Developmental Lung Biology Research

  17. Lung, Artificial: Basic Principles and Current Applications William J. Federspiel

    E-Print Network [OSTI]

    Federspiel, William J.

    Lung, Artificial: Basic Principles and Current Applications William J. Federspiel Kristie A. Henchir University of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A. INTRODUCTION Artificial lungs currently of the lung, which is to oxygenate the blood and remove carbon dioxide. Current artificial lungs are also

  18. GREIT: towards a consensus EIT algorithm for lung images

    E-Print Network [OSTI]

    Adler, Andy

    GREIT: towards a consensus EIT algorithm for lung images Andy Adler1 , John Arnold2 , Richard in the patient's lungs. However, most clinical and physiological research in lung EIT is done using older reconstruction algorithm for lung EIT, called GREIT (Graz consensus Reconstruc- tion algorithm for EIT

  19. Estimating Volumes of Simulated Lung Cancer Nodules David E. Gilsinn

    E-Print Network [OSTI]

    Gilsinn, David E.

    Estimating Volumes of Simulated Lung Cancer Nodules David E. Gilsinn Bruce R. Borchardt Amelia Tebbe§ July 15, 2009 Abstract Lung cancer is a disease of uncontrolled cell growth in tissues of the lung. Computed to- mography (CT) shows promise in detecting lung cancers at earlier, more operable

  20. Collapsibility of Lung Volume by Paired Inspiratory and Expiratory CT

    E-Print Network [OSTI]

    Collapsibility of Lung Volume by Paired Inspiratory and Expiratory CT Scans: Correlations with Lung Function and Mean Lung Density Tsuneo Yamashiro, MD, Shin Matsuoka, MD, PhD, Brian J. Bartholmai, MD, Rau: To evaluate the relationship between measurements of lung volume (LV) on inspiratory/expiratory computed

  1. Numerical study of variable lung ventilation strategies

    E-Print Network [OSTI]

    Yadav, Reena; Hiremath, Kirankumar; Bagler, Ganesh

    2015-01-01

    Mechanical ventilation is used for patients with a variety of lung diseases. Traditionally, ventilators have been designed to monotonously deliver equal sized breaths. While it may seem intuitive that lungs may benefit from unvarying and stable ventilation pressure strategy, recently it has been reported that variable lung ventilation is advantageous. In this study, we analyze the mean tidal volume in response to different `variable ventilation pressure' strategies. We found that uniformly distributed variability in pressure gives the best tidal volume as compared to that of normal, scale- free, log normal and linear distributions.

  2. Americans Abroad: A Global Diaspora?

    E-Print Network [OSTI]

    Croucher, Sheila

    2012-01-01

    D. “Confederate Migration to Mexico. ” Hispanic AmericanHarmon, “Confederate Migration to Mexico,” Hispanic AmericanUS Retirement Migration to Mexico and Panama. Washington,

  3. Lung Cancer . Author manuscript p16INK4A inactivation mechanisms in non-small-cell lung cancer patients

    E-Print Network [OSTI]

    Boyer, Edmond

    Lung Cancer . Author manuscript Page /1 10 p16INK4A inactivation mechanisms in non-small-cell lung occupational risk factor and that asbestos acts synergistically with tobacco smoking to induce lung cancer. Although some somatic gene alterations in lung cancer have been linked to tobacco smoke, few data

  4. 82 SESSION 9. LUNGS II Using EIT to determine the role of gestational age on lung volume

    E-Print Network [OSTI]

    Adler, Andy

    82 SESSION 9. LUNGS II Using EIT to determine the role of gestational age on lung volume response calculated for preterm and extremely preterm lambs. 1 Introduction Lung aeration is the first process the newly born lung needs to achieve at birth if the transition from in-utero life is to be successful

  5. The role of uPAR signaling in lung cancer Background and significance

    E-Print Network [OSTI]

    Gleeson, Joseph G.

    The role of uPAR signaling in lung cancer Background and significance Lung cancer is the leading of lung cancer ­ non-small-cell-lung cancer (about 85% of all lung cancer cases) and small- cell-lung cancer (about 15%) (Herbst et al., 2008). Small cell lung carcinoma (SCLC) is rapidly growing and often

  6. Predicting Pneumonitis Risk: A Dosimetric Alternative to Mean Lung Dose

    SciTech Connect (OSTI)

    Tucker, Susan L.; Mohan, Radhe; Liengsawangwong, Raweewan; Martel, Mary K.; Liao Zhongxing

    2013-02-01

    Purpose: To determine whether the association between mean lung dose (MLD) and risk of severe (grade {>=}3) radiation pneumonitis (RP) depends on the dose distribution pattern to normal lung among patients receiving 3-dimensional conformal radiation therapy for non-small-cell lung cancer. Methods and Materials: Three cohorts treated with different beam arrangements were identified. One cohort (2-field boost [2FB]) received 2 parallel-opposed (anteroposterior-posteroanterior) fields per fraction initially, followed by a sequential boost delivered using 2 oblique beams. The other 2 cohorts received 3 or 4 straight fields (3FS and 4FS, respectively), ie, all fields were irradiated every day. The incidence of severe RP was plotted against MLD in each cohort, and data were analyzed using the Lyman-Kutcher-Burman (LKB) model. Results: The incidence of grade {>=}3 RP rose more steeply as a function of MLD in the 2FB cohort (N=120) than in the 4FS cohort (N=138), with an intermediate slope for the 3FS group (N=99). The estimated volume parameter from the LKB model was n=0.41 (95% confidence interval, 0.15-1.0) and led to a significant improvement in fit (P=.05) compared to a fit with volume parameter fixed at n=1 (the MLD model). Unlike the MLD model, the LKB model with n=0.41 provided a consistent description of the risk of severe RP in all three cohorts (2FB, 3FS, 4FS) simultaneously. Conclusions: When predicting risk of grade {>=}3 RP, the mean lung dose does not adequately take into account the effects of high doses. Instead, the effective dose, computed from the LKB model using volume parameter n=0.41, may provide a better dosimetric parameter for predicting RP risk. If confirmed, these findings support the conclusion that for the same MLD, high doses to small lung volumes ('a lot to a little') are worse than low doses to large volumes ('a little to a lot').

  7. PCA-based lung motion model

    E-Print Network [OSTI]

    Li, Ruijiang; Jia, Xun; Zhao, Tianyu; Lamb, James; Yang, Deshan; Low, Daniel A; Jiang, Steve B

    2010-01-01

    Organ motion induced by respiration may cause clinically significant targeting errors and greatly degrade the effectiveness of conformal radiotherapy. It is therefore crucial to be able to model respiratory motion accurately. A recently proposed lung motion model based on principal component analysis (PCA) has been shown to be promising on a few patients. However, there is still a need to understand the underlying reason why it works. In this paper, we present a much deeper and detailed analysis of the PCA-based lung motion model. We provide the theoretical justification of the effectiveness of PCA in modeling lung motion. We also prove that under certain conditions, the PCA motion model is equivalent to 5D motion model, which is based on physiology and anatomy of the lung. The modeling power of PCA model was tested on clinical data and the average 3D error was found to be below 1 mm.

  8. Lung Nodule Detection in Screening Computed Tomography

    E-Print Network [OSTI]

    Gori, I; Cerello, P; Cheran, S C; De Nunzio, G; Fantacci, M E; Kasae, P; Masala, G L; Pérez-Martínez, A; Retico, A

    2007-01-01

    A computer-aided detection (CAD) system for the identification of pulmonary nodules in low-dose multi-detector helical Computed Tomography (CT) images with 1.25 mm slice thickness is presented. The basic modules of our lung-CAD system, a dot-enhancement filter for nodule candidate selection and a neural classifier for false-positive finding reduction, are described. The results obtained on the collected database of lung CT scans are discussed.

  9. Copyright 1998, American Institute of Aeronautics and Astronautics, Inc. A98-32439 AIAA-98-2626

    E-Print Network [OSTI]

    Riabov, Vladimir V.

    Copyright© 1998, American Institute of Aeronautics and Astronautics, Inc. A98-32439 AIAA-98, Associate Fellow AJAA. Copyright > 1998 by the American Institute of Aeronautics and Astronautics. Inc. All of Aeronautics and Astronautics #12;Copyright© 1998, American Institute of Aeronautics and Astronautics, Inc

  10. AFRICAN AMERICAN PSYCHOLOGY Sample Syllabus

    E-Print Network [OSTI]

    Hopfinger, Joseph B.

    AFRICAN AMERICAN PSYCHOLOGY PSYC 503 Sample Syllabus Course Description and Overview: This course examines the psychology of the African American experience. We begin the course with an overview of Black/African American psychology as an evolving field of study and consider the Black/African American Psychology

  11. Radiation-induced lung injury

    SciTech Connect (OSTI)

    Rosiello, R.A.; Merrill, W.W. )

    1990-03-01

    The use of radiation therapy is limited by the occurrence of the potentially fatal clinical syndromes of radiation pneumonitis and fibrosis. Radiation pneumonitis usually becomes clinically apparent from 2 to 6 months after completion of radiation therapy. It is characterized by fever, cough, dyspnea, and alveolar infiltrates on chest roentgenogram and may be difficult to differentiate from infection or recurrent malignancy. The pathogenesis is uncertain, but appears to involve both direct lung tissue toxicity and an inflammatory response. The syndrome may resolve spontaneously or may progress to respiratory failure. Corticosteroids may be effective therapy if started early in the course of the disease. The time course for the development of radiation fibrosis is later than that for radiation pneumonitis. It is usually present by 1 year following irradiation, but may not become clinically apparent until 2 years after radiation therapy. It is characterized by the insidious onset of dyspnea on exertion. It most often is mild, but can progress to chronic respiratory failure. There is no known successful treatment for this condition. 51 references.

  12. White Paper Developed by the American Gas Association and American Public Gas Association

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION J APPENDIX E LIST OFAMERICA'S FUTURE. regulatorsEnergyDepartment ofNuclearWhereEnergy

  13. Lienert named American Welding Society Fellow

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Lienert Named American Welding Society Fellow Lienert named American Welding Society Fellow Lienert was inducted into the American Welding Society's 2012 Class of Fellows during...

  14. Visual Power: 21st Century Native American Artists/Intellectuals

    E-Print Network [OSTI]

    Farris, Phoebe

    2006-10-01

    to include ex hibits reflecting such diverse cultures as African American Quilts, Ester Hernandez: The Art of Provocation, and Co-Madres Artistas: Voces de laMujer, while still maintaining a strong Native American presence. His own work uses pop culture... art. Visual Power is an outgrowth of a 2003 College Art Association panel that I chaired titled Native American Artists/Intellectuals: Speaking for Ourselves in the 21st Century and a concurrent art exhibition of the same title that I guest curated...

  15. Asian American women entrepreneurs

    E-Print Network [OSTI]

    Suh, Clara J

    2014-01-01

    There are an estimated 620,300 firms owned by Asian American women nationwide, and they contribute $105 billion to the U.S. economy. They are also active in Greater Boston's innovation and entrepreneurship communities. ...

  16. The great American garage

    E-Print Network [OSTI]

    Miller, B. Alex (Brian Alex), 1977-

    2004-01-01

    How does one explore the suburban home? Go in through the garage, of course. Sales, bands, suicides, and business startups: The suburban garage is the most culturally flexible space in the entire American domestic environment. ...

  17. American Nuclear Society Awards

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Nuclear Society Awards Established in 1999 by the Fusion Energy Division of the American Nuclear Society (ANS) and named after LLNL's co-founder, the Edward Teller Medal recognizes...

  18. Latin American Political Trends and their Impact on the Future of U.S.-Latin American Relations 

    E-Print Network [OSTI]

    Davis, Andrew Milton

    2010-07-14

    -1 LATIN AMERICAN POLITICAL TRENDS AND THEIR IMPACT ON THE FUTURE OF U.S.-LATIN AMERICAN RELATIONS Major: International Studies April 2010 Submitted to the Honors Programs Office Texas A&M University in partial fulfillment of the requirements...: Michelle Taylor-Robinson Associate Director of the Honors Programs Office: Dave A. Louis Major: International Studies April 2010 Submitted to the Honors Programs Office Texas A&M University in partial fulfillment of the requirements...

  19. www.yalecancercenter.org The Biology of Lung Cancer

    E-Print Network [OSTI]

    O'Hern, Corey S.

    www.yalecancercenter.org The Biology of Lung Cancer Guest Expert: Katerina Politi, PhD www lung cancers and cutaneous lymphomas. If you would like to join the conversation, you can contact

  20. NF-?B Fans the Flames of Lung Carcinogenesis

    E-Print Network [OSTI]

    Jacks, Tyler E.

    This perspective on Deng et al. (beginning on p. 424 in this issue of the journal) examines the link between NF-?B and lung tumorigenesis. Experiments in genetically engineered mouse models of lung cancers are elucidating ...

  1. Differentiation of normal and cancerous lung tissues by multiphoton imaging

    E-Print Network [OSTI]

    Wang, Chun-Chin

    We utilize multiphoton microscopy for the label-free diagnosis of noncancerous, lung adenocarcinoma (LAC), and lung squamous cell carcinoma (SCC) tissues from humans. Our results show that the combination of second-harmonic ...

  2. CENTER FOR ENVIRONMENTAL MEDICINE, ASTHMA AND LUNG BIOLOGY PUBLICATIONS (2008)

    E-Print Network [OSTI]

    Crews, Stephen

    2008-01-01

    CENTER FOR ENVIRONMENTAL MEDICINE, ASTHMA AND LUNG BIOLOGY PUBLICATIONS (2008) Alexis NE, Muhlebach MS, Peden DB, Noah TL. Attenuation of host defense function of lung phagocytes in early cystic

  3. ORIGINAL RESEARCH Chung-Horng Lung Joseph E. Urban

    E-Print Network [OSTI]

    Lung, Chung-Horng

    ORIGINAL RESEARCH Chung-Horng Lung Æ Joseph E. Urban Gerald T. Mackulak Analogy-based domain problem that shares significant aspects with the past problem and C.-H. Lung (&) Department of Systems

  4. Survival after Radiofrequency Ablation in 122 Patients with Inoperable Colorectal Lung Metastases

    SciTech Connect (OSTI)

    Gillams, Alice, E-mail: alliesorting@gmail.com [The London Clinic, Radiology Department (United Kingdom); Khan, Zahid [Countess of Chester Hospital (United Kingdom); Osborn, Peter [Queen Alexandra Hospital (United Kingdom); Lees, William [University College London Medical School (United Kingdom)

    2013-06-15

    Purpose. To analyze the factors associated with favorable survival in patients with inoperable colorectal lung metastases treated with percutaneous image-guided radiofrequency ablation. Methods. Between 2002 and 2011, a total of 398 metastases were ablated in 122 patients (87 male, median age 68 years, range 29-90 years) at 256 procedures. Percutaneous CT-guided cool-tip radiofrequency ablation was performed under sedation/general anesthesia. Maximum tumor size, number of tumors ablated, number of procedures, concurrent/prior liver ablation, previous liver or lung resection, systemic chemotherapy, disease-free interval from primary resection to lung metastasis, and survival from first ablation were recorded prospectively. Kaplan-Meier analysis was performed, and factors were compared by log rank test. Results. The initial number of metastases ablated was 2.3 (range 1-8); the total number was 3.3 (range 1-15). The maximum tumor diameter was 1.7 (range 0.5-4) cm, and the number of procedures was 2 (range 1-10). The major complication rate was 3.9 %. Overall median and 3-year survival rate were 41 months and 57 %. Survival was better in patients with smaller tumors-a median of 51 months, with 3-year survival of 64 % for tumors 2 cm or smaller versus 31 months and 44 % for tumors 2.1-4 cm (p = 0.08). The number of metastases ablated and whether the tumors were unilateral or bilateral did not affect survival. The presence of treated liver metastases, systemic chemotherapy, or prior lung resection did not affect survival. Conclusion. Three-year survival of 57 % in patients with inoperable colorectal lung metastases is better than would be expected with chemotherapy alone. Patients with inoperable but small-volume colorectal lung metastases should be referred for ablation.

  5. Annabella: a North American coasting vessel 

    E-Print Network [OSTI]

    Claesson, Stefan Hans

    1998-01-01

    schooner in 1841. 53 26 Map of southern New Jersey. 60 27 28 Section lines of the preserved remains of Annabella. . . . . Lines of a Milford, Delaware vessel. . . . . . . . . . . . . . . . . . . 66 FIGURE Page 29 A billet head of a 19th... enrolment records. . 54 Measurements of Milford, Delaware-built sloops in comparison to Annabella, 69 Timber dimensions required for construction of 100 ton vessel by American Shipmaster's Association in 1882 compared to timber dimensions of Annabella...

  6. Midwest Area Chinese American Resources Guide

    E-Print Network [OSTI]

    Chinese American Librarians Association - Midwest Chapter; Wu, Pei-ling; McElroy, Anna; Chang, Ling-li; Sanders, R. Bruce; Lin, Shao-Chen

    1995-01-01

    Copyright 1995 by the Chinese American Librarians Association - Midwest Chapter. All rights reserved. No part of this book may be reproduced. stored, or transmitted by any means without written permission from the publisher. Please send all written..., appointed by the president, include program planning, electronic publishing, nomination, public relations, and special task forces . State contacts are recruited by the vice president. Election usually takes place at the annual meeting held in April or May...

  7. Analysis of lung tumor initiation and progression in transgenic mice for Cre-inducible overexpression of Cul4A gene

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Wang, Yang; Xu, Zhidong; Mao, Jian -Hua; Hung, Ming -Szu; Hsieh, David; Au, Alfred; Jablons, David M.; You, Liang

    2015-06-08

    Background: Lung cancer is the leading cause of morbidity and death worldwide. Although the available lung cancer animal models have been informative and further propel our understanding of human lung cancer, they still do not fully recapitulate the complexities of human lung cancer. The pathogenesis of lung cancer remains highly elusive because of its aggressive biologic nature and considerable heterogeneity, compared to other cancers. The association of Cul4A amplification with aggressive tumor growth and poor prognosis has been suggested. Our previous study suggested that Cul4A is oncogenic in vitro, but its oncogenic role in vivo has not been studied. Methods:more »Viral delivery approaches have been used extensively to model cancer in mouse models. In our experiments, we used Cre-recombinase induced overexpression of the Cul4A gene in transgenic mice to study the role of Cul4A on lung tumor initiation and progression and have developed a new model of lung tumor development in mice harboring a conditionally expressed allele of Cul4A. Results: Here we show that the use of a recombinant adenovirus expressing Cre-recombinase (“AdenoCre”) to induce Cul4A overexpression in the lungs of mice allows controls of the timing and multiplicity of tumor initiation. Following our mouse models, we are able to study the potential role of Cul4A in the development and progression in pulmonary adenocarcinoma as well. Conclusion: Our findings indicate that Cul4A is oncogenic in vivo, and this mouse model is a tool in understanding the mechanisms of Cul4A in human cancers and for testing experimental therapies targeting Cul4A.« less

  8. Polarized Helium to Image the Lung

    E-Print Network [OSTI]

    Leduc, M; Leduc, Mich\\`{e}le; Nacher, Pierre-Jean

    2006-01-01

    The main findings of the european PHIL project (Polarised Helium to Image the Lung) are reported. State of the art optical pumping techniques for polarising ^3He gas are described. MRI methodological improvements allow dynamical ventilation images with a good resolution, ultimately limited by gas diffusion. Diffusion imaging appears as a robust method of lung diagnosis. A discussion of the potential advantage of low field MRI is presented. Selected PHIL results for emphysema are given, with the perspectives that this joint work opens up for the future of respiratory medicine.

  9. Journal of Comparative Psychology Copyright 2000 by the American Psychological Association, Inc. 2000, Vol. 114, No. 3, 281-290 0735-7036/00t$5.00 DOI: 10.10371/0735-7036.114.3.281

    E-Print Network [OSTI]

    Berridge, Kent

    H. Owings University of California, Davis Animal communication theory holds that many signals have is an ancient, endogenously sequenced (syntactic) pattern of cephalocaudal grooming movements (CCGs) shared cephalocaudal pattern; (c) were associated with scent marking and social stating; and (d) were associated

  10. www.yalecancercenter.org Robotic Surgery for Lung Cancer

    E-Print Network [OSTI]

    O'Hern, Corey S.

    www.yalecancercenter.org Robotic Surgery for Lung Cancer Guest Expert: Anthony Kim, MD Assistant and an expert in the use of radiation to treat lung cancers and cutaneous lymphomas. If you would like to join for a conversation about robotic surgery for lung cancer. Here is Francine Foss. Foss Let's start off by talking

  11. www.yalecancercenter.org Non-Small Cell Lung Cancer

    E-Print Network [OSTI]

    O'Hern, Corey S.

    www.yalecancercenter.org Non-Small Cell Lung Cancer Therapies Guest Expert: Roy Decker, MD, Ph Scott, let's start off by discussing why lung cancer is still such a significant public health problem it has decreased in the last 10- 15 years. The incidence of lung cancer might be decreasing a little

  12. A Bronchial Puncture Mechanism for Transoral Access to the Lung

    E-Print Network [OSTI]

    A Bronchial Puncture Mechanism for Transoral Access to the Lung Parenchyma Erik P. Lamers, Andria A University 1 Background More people die from lung cancer each year than any other form of cancer. Over 150 tool. The most common lung biopsy approaches are percutaneous and transoral. Percutaneous biopsy

  13. Nanostructure Changes in Lung Surfactant Monolayers Induced by Interactions between

    E-Print Network [OSTI]

    Zasadzinski, Joseph A.

    Nanostructure Changes in Lung Surfactant Monolayers Induced by Interactions between: October 4, 2002 Developing synthetic lung surfactants to replace animal extracts requires a fundamental understanding of the roles of the various lipids and proteins in native lung surfactant. We used Brewster angle

  14. Cardiopulmonary Function in RatsWith Lung Hemorrhage

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Cardiopulmonary Function in RatsWith Lung Hemorrhage Induced by Pulsed Ultrasound Exposure Jeffery using superthreshold exposure conditions known to produce sig- nificant lung hemorrhage. Methods. In 1 in the left lung of each rat. In a second group of 6 rats, 5 foci of ultrasound-induced hemorrhage were

  15. The Comprehensive Imaging-Based Analysis of the Lung

    E-Print Network [OSTI]

    Wang, Ge

    The Comprehensive Imaging-Based Analysis of the Lung: A Forum for Team Science1 Eric A. Hoffman, Ph description and understanding of the human lung and its response to disease, injury, and treatment, which for the need to volumetrically im- age the lung and to provide objective, quantitative measures characterizing

  16. Dynamic Lung Morphology of Methacholine-Induced Heterogeneous Bronchoconstriction

    E-Print Network [OSTI]

    Dynamic Lung Morphology of Methacholine-Induced Heterogeneous Bronchoconstriction Ben T. Chen and G). The method provides direct visualization of the venti- lated regions within the lung. Heterogeneous bronchoconstric- tion following the i.v. MCh injection was evident using this technique. These 3 He dynamic lung

  17. Tomographic Digital Subtraction Angiography for Lung Perfusion Estimation in Rodents

    E-Print Network [OSTI]

    Tomographic Digital Subtraction Angiography for Lung Perfusion Estimation in Rodents Cristian T. The capabilities of TDSA are established in studies on lung perfusion in rats. Using an imaging system developed in to therapeutics. Keywords X-ray; digital subtraction angiography; tomosynthesis; small animal; lung; perfusion

  18. Computerised lung sound analysis to improve the specificity of paediatric

    E-Print Network [OSTI]

    Elhilali, Mounya

    Computerised lung sound analysis to improve the specificity of paediatric pneumonia diagnosis that pulmonary pathology can be differentiated from normal using computerised lung sound analysis (CLSA). The authors will record lung sounds from 600 children aged #5 years, 100 each with consolidative pneumonia

  19. Predicting Panel Ratings for Semantic Characteristics of Lung Nodules

    E-Print Network [OSTI]

    Schaefer, Marcus

    Predicting Panel Ratings for Semantic Characteristics of Lung Nodules Dmitriy Zinovev De@cdm.depaul.edu ABSTRACT In reading CT scans with potentially malignant lung nodules, radiologists make use of high level a second opinion - predicting these semantic characteristics for lung nodules. In our previous work, we

  20. RESEARCH ARTICLE Open Access Occupational exposure to asbestos and lung

    E-Print Network [OSTI]

    Boyer, Edmond

    RESEARCH ARTICLE Open Access Occupational exposure to asbestos and lung cancer in men: evidence consistently demonstrated that workplace exposure to it increases the risk of developing lung cancer. Few of lung cancer, and 2,053 controls recruited from 8 Canadian provinces between 1994 and 1997. Self

  1. INVESTIGATION The Lsktm1 Locus Modulates Lung and Skin

    E-Print Network [OSTI]

    Broman, Karl W.

    INVESTIGATION The Lsktm1 Locus Modulates Lung and Skin Tumorigenesis in the Mouse Antonella Galvan to both skin and lung tumorigenesis over the susceptibility of the SWR/J strain. In an effort to map tumor.93) and lung (LOD score = 8.74) tumorigenesis. Two genes, Igfbp5 and Igfbp2, residing in this locus

  2. Measurement of Regional Lung Function in Rats Using Hyperpolarized 3

    E-Print Network [OSTI]

    Measurement of Regional Lung Function in Rats Using Hyperpolarized 3 Helium Dynamic MRI Ben T. Chen,* Anja C.S. Brau, and G. Allan Johnson Dynamic regional lung function was investigated in rats using by a constant flow ventila- tor. Based on regional differences in the behavior of inspired air, the lung

  3. Early Recognition of Lung's Air Sacs Wall Collapsing

    E-Print Network [OSTI]

    Boyer, Edmond

    Early Recognition of Lung's Air Sacs Wall Collapsing M. EMAM, J-F RENAUD de la Faverie, N. GHARBI discusses the possibility of applying a non- liner analysis approach on air density distribution within lung airways tree at any level of branching1. Computed Tomography (CT) 2 source images of the lung

  4. Cell Stem Cell Generation of Multipotent Lung and Airway

    E-Print Network [OSTI]

    Mootha, Vamsi K.

    Cell Stem Cell Article Generation of Multipotent Lung and Airway Progenitors from Mouse ESCs.01.018 SUMMARY Deriving lung progenitors from patient-specific pluripotent cells is a key step in producing differenti- ated lung epithelium for disease modeling and trans- plantation. By mimicking the signaling

  5. NHLBI Workshop Future Directions in Early Cystic Fibrosis Lung

    E-Print Network [OSTI]

    Engelhardt, John F.

    NHLBI Workshop Future Directions in Early Cystic Fibrosis Lung Disease Research An NHLBI Workshop of Washington School of Medicine, Seattle, Washington; 3 National Heart, Lung, and Blood Institute, National substantial progress toward under- standing the molecular basis for CF lung disease, leading to the discovery

  6. Original article Lentivirus-induced interstitial lung disease

    E-Print Network [OSTI]

    Boyer, Edmond

    Original article Lentivirus-induced interstitial lung disease: pulmonary pathology in sheep a chronic disease in sheep affecting, among other organs, the lungs. Interstitial pneumonitis is similar the pathological features of lungs of sheep naturally infected with visna-maedi virus with the results obtained

  7. Visualization of Density Variation in Lung Aristofanes C. Silva

    E-Print Network [OSTI]

    Endler, Markus

    Visualization of Density Variation in Lung Nodules Arist´ofanes C. Silva e-mail: ari-Rio Inf.MCC09/02 June, 2002 Abstract We propose a method for visualize lung nodule, in order to emphasize, limiar. #12;1 Introduction Lung cancer is known to be the form of cancer with the smallest survival rate

  8. Lung Disease in Pediatrics: is it all in the Genes?

    E-Print Network [OSTI]

    Lung Disease in Pediatrics: is it all in the Genes? Jay K. Kolls, M.D.Jay K. Kolls, M.D. Chair with CF do worse than other? #12;· Outcomes are better at CF centers · There is huge variation in lung with the same mutation do worse than others? · Modifier genes ­ lung disease ­ Tgfb1 ­ Irfd1 ­ neutrophil

  9. Changes in Model Lung Surfactant Monolayers Induced by Palmitic Acid

    E-Print Network [OSTI]

    Zasadzinski, Joseph A.

    Changes in Model Lung Surfactant Monolayers Induced by Palmitic Acid Frank Bringezu, Junqi Ding of model lung surfactant lipid monolayers. Adding increasing fractions of palmitic acid (PA) to a 77/23 (wt to the rational design of replacement lung surfactants for the treatment of respiratory distress syndrome

  10. Biomaterials 28 (2007) 31313139 Towards improved artificial lungs through biocatalysis

    E-Print Network [OSTI]

    Federspiel, William J.

    2007-01-01

    Biomaterials 28 (2007) 3131­3139 Towards improved artificial lungs through biocatalysis Joel L in the development of artificial lungs and respiratory assist devices, which use hollow fiber membranes (HFMs intervention involves the use of mechan- ical ventilators to provide breathing support while the lungs recover

  11. ORIGINAL ARTICLE Effect of Different Sitting Postures on Lung Capacity,

    E-Print Network [OSTI]

    Makhsous, Mohsen

    ORIGINAL ARTICLE Effect of Different Sitting Postures on Lung Capacity, Expiratory Flow, and Lumbar, Makhsous M. Effect of different sitting postures on lung capacity, expiratory flow, and lumbar lordosis. Arch Phys Med Rehabil 2006;87:504-9. Objective: To investigate the effect of sitting posture on lung

  12. Lung, Artificial: Current Research and Future Directions William J. Federspiel

    E-Print Network [OSTI]

    Federspiel, William J.

    Lung, Artificial: Current Research and Future Directions William J. Federspiel Robert G. Svitek University of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A. INTRODUCTION Artificial lungs are medical devices designed to take over or supplement the respiratory function of the lung: oxygenating the blood

  13. Evaluation of Plasma Resistant Hollow Fiber Membranes For Artificial Lungs

    E-Print Network [OSTI]

    Federspiel, William J.

    Evaluation of Plasma Resistant Hollow Fiber Membranes For Artificial Lungs HEIDE J. EASH,* HEATHER in artificial lungs (ox- ygenators) undergo plasma leakage (or wetting) in which blood plasma slowly fills2 gas permeance of a plasma resistant fiber imposes the greatest constraint upon artificial lung

  14. Lung Segmentation from CT with Severe Pathologies Using Anatomical Constraints

    E-Print Network [OSTI]

    Lung Segmentation from CT with Severe Pathologies Using Anatomical Constraints Neil Birkbeck Healthcare, Oxford, UK Abstract. The diversity in appearance of diseased lung tissue makes automatic segmentation of lungs from CT with severe pathologies chal- lenging. To overcome this challenge, we rely

  15. Computational Model for Forced Expiration from Asymmetric Normal Lungs

    E-Print Network [OSTI]

    Lutchen, Kenneth

    Computational Model for Forced Expiration from Asymmetric Normal Lungs ADAM G. POLAK 1 losses along the airway branches. Calculations done for succeeding lung volumes result in the semidynamic to the choke points, characteristic differences of lung regional pressures and volumes, and a shape

  16. ORIGINAL RESEARCH Attenuation of Lipopolysaccharide-Induced Lung Vascular

    E-Print Network [OSTI]

    Gardel, Margaret

    ORIGINAL RESEARCH Attenuation of Lipopolysaccharide-Induced Lung Vascular Stiffening by Lipoxin Reduces Lung Inflammation Fanyong Meng1 , Isa Mambetsariev1 , Yufeng Tian1 , Yvonne Beckham2 , Angelo. Birukova1 1 Lung Injury Center, Section of Pulmonary and Critical Care Medicine, Department of Medicine

  17. Lung Cancer and Arsenic Concentrations in Drinking Water in Chile

    E-Print Network [OSTI]

    California at Berkeley, University of

    Lung Cancer and Arsenic Concentrations in Drinking Water in Chile Catterina Ferreccio,1,2 Claudia- trations have since been reduced to 40 g/liter. We investi- gated the relation between lung cancer and arsenic in drinking water in northern Chile in a case-control study involving patients diagnosed with lung

  18. Diversity of gene expression in adenocarcinoma of the lung

    E-Print Network [OSTI]

    Botstein, David

    Diversity of gene expression in adenocarcinoma of the lung Mitchell E. Garber*, Olga G. Troyanskaya Contributed by David Botstein, September 21, 2001 The global gene expression profiles for 67 human lung tumors pathologic analysis. Four main histologic subtypes of lung cancer are regularly distinguished by tumor

  19. Identification of Early Interstitial Lung Disease in Smokers from the

    E-Print Network [OSTI]

    Identification of Early Interstitial Lung Disease in Smokers from the COPDGene Study George R interstitial lung disease (ILD) on chest computed tomographic (CT) scans. Materials and Methods: The CT scans: Early interstitial lung disease; CT scan; smoker. ªAUR, 2010 I diopathic pulmonary fibrosis (IPF

  20. Asymmetries in Electrical Impedance Tomography Lung Images Bartlomiej Grychtol1

    E-Print Network [OSTI]

    Adler, Andy

    Asymmetries in Electrical Impedance Tomography Lung Images Bartlomiej Grychtol1 and Andy Adler2 1, it has been used to image the thorax, to monitor the movement of blood and gas in the heart and lungs. One key application of EIT is to determine the distribution of ventilation within the lungs

  1. Targeted CT Screening for Lung Cancer using Absolute Risk Prediction

    E-Print Network [OSTI]

    Brent, Roger

    Targeted CT Screening for Lung Cancer using Absolute Risk Prediction Stephanie A. Kovalchik skovalch@rand.org FHCRC 2014 Risk Prediction Symposium June 11, 2014 1 #12;Outline · Lung Cancer Epidemiology and Screening · Screening Benefit and Absolute Risk · Absolute Risk Model for Lung Cancer

  2. VARIATIONAL APPROACH FOR SEGMENTATION OF LUNG NODULES Amal A. Faraga

    E-Print Network [OSTI]

    Louisville, University of

    VARIATIONAL APPROACH FOR SEGMENTATION OF LUNG NODULES Amal A. Faraga , Hossam Abdelmunimab , James, Louisville, Kentucky g University of Louisville, Department of Radiology ABSTRACT Lung nodules from low dose CT (LDCT) scans may be used for early detection of lung cancer. However, these nodules vary in size

  3. -Glutamyl transferase deficiency results in lung oxidant stress in normoxia

    E-Print Network [OSTI]

    Marc, Robert E.

    -Glutamyl transferase deficiency results in lung oxidant stress in normoxia JYH CHANG JEAN,1 YUE E. Marc, Elizabeth Klings, and Martin Joyce-Brady. -Glutamyl transferase deficiency results in lung oxidant stress in normoxia. Am J Physiol Lung Cell Mol Physiol 283: L766­L776, 2002. First published May 3

  4. Buccal Spectral Markers for Lung Cancer Risk Stratification

    E-Print Network [OSTI]

    Hartline, Jason D.

    Buccal Spectral Markers for Lung Cancer Risk Stratification Andrew J. Radosevich1 *, Nikhil N, United States of America Abstract Lung cancer remains the leading cause of cancer deaths in the US with .150,000 deaths per year. In order to more effectively reduce lung cancer mortality, more sophisticated

  5. a bStomach Lung cell zone Clara cell

    E-Print Network [OSTI]

    Krasnow, Mark A.

    a bStomach Lung Chief-cell zone Stem-cell zone Mucus- cell zone Clara cell Tracheal airway Basal independent studies show that, if push comes to shove, differentiated cells of the stomach and lung can act and the other by Stange et al.2 published in Cell, find that followingdepletionofstemcellsinthestomach or lung

  6. EIT measurement of heart and lung perfusion Helga Ross1

    E-Print Network [OSTI]

    Adler, Andy

    EIT measurement of heart and lung perfusion Helga Ross1 , Benjamin J.W. Chow2 , and Andy Adler1 1. Introduction Electrical Impedance Tomography (EIT) shows promise for monitoring a patient's heart and lungs matching in the lungs. The goal of this research is to determine the accuracy of EIT measurements of blood

  7. Special Article Elucidating Nature's Solutions to Heart, Lung, and Blood

    E-Print Network [OSTI]

    Storz, Jay F.

    Special Article Elucidating Nature's Solutions to Heart, Lung, and Blood Diseases and Sleep defenses, and oxygen transport. In 2006, the National Heart, Lung, and Blood Institute released a funding understanding of nature's solutions to heart, lung, blood, and sleep disorders through future research

  8. A Case Report of 20 Lung Radiofrequency Ablation Sessions for 50 Lung Metastases from Parathyroid Carcinoma Causing Hyperparathyroidism

    SciTech Connect (OSTI)

    Tochio, Maki, E-mail: m-tochio@clin.medic.mie-u.ac.jp; Takaki, Haruyuki; Yamakado, Koichiro; Uraki, Junji; Kashima, Masataka; Nakatsuka, Atsuhiro [Mie University School of Medicine, Department of Radiology (Japan); Takao, Motoshi; Shimamoto, Akira; Tarukawa, Tomohito; Shimpo, Hideto [Mie University School of Medicine, Department of Thoracic and Cardiovascular Surgery (Japan); Takeda, Kan [Mie University School of Medicine, Department of Radiology (Japan)

    2010-06-15

    A 47-year-old man presented with multiple lung metastases from parathyroid carcinoma that caused hyperparathyroidism and refractory hypercalcemia. Lung radiofrequency (RF) ablation was repeated to decrease the serum calcium and parathyroid hormone levels and improve general fatigue. Pulmonary resection was combined for lung hilum metastases. The patient is still alive 4 years after the initial RF session. He has received 20 RF sessions for 50 lung metastases during this period.

  9. Mouse models of lung cancer : understanding the molecular and cellular basis of lung tumorigenesis

    E-Print Network [OSTI]

    Jackson, Erica L. (Erica Lynn), 1973-

    2003-01-01

    Lung cancer is the leading cause of cancer deaths worldwide. Patients are typically diagnosed with advanced disease and have a high fatality:case ratio. Despite its prevalence, the identity of the cell of origin, precursor ...

  10. 56 SCIENTIFIC AMERICAN APRIL 2006 COPYRIGHT 2006 SCIENTIFIC AMERICAN, INC.

    E-Print Network [OSTI]

    Robins, Gabriel

    56 SCIENTIFIC AMERICAN APRIL 2006 COPYRIGHT 2006 SCIENTIFIC AMERICAN, INC. #12;www.sciam.com SCIENTIFIC AMERICAN 57 Computing with Quantum Knots uantum computers promise to perform calculations be- lieved to be impossible for ordinary computers. Some of those calculations are of great real-world

  11. Small RNA combination therapy for lung cancer

    E-Print Network [OSTI]

    Tammela, Tuomas

    MicroRNAs (miRNAs) and siRNAs have enormous potential as cancer therapeutics, but their effective delivery to most solid tumors has been difficult. Here, we show that a new lung-targeting nanoparticle is capable of delivering ...

  12. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Shen, Jun

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : What You Need To Know About High- tors for heart disease. In fact, the higher your blood cholesterol, the greater your risk of developing heart disease or having a heart attack. Heart disease is the #1 killer of men and women in the United

  13. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Shen, Jun

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : Physical Activity and Your Heart, is that even modest amounts of physi- cal activity are good for your health, especially your heart health activity is the type of physical activity that benefits your heart the most. This type of activity moves

  14. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Shen, Jun

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : Coronary Heart Disease C oronary heart disease (CHD), also called coronary artery disease, is the leading cause of death in the United. These arteries supply your heart muscle with oxygen-rich blood. Plaque is made up of fat, cholesterol, calcium

  15. Effects of effluents of coal combustion and gasification upon lung structure and function. Annual report

    SciTech Connect (OSTI)

    Hinton, D.E.

    1980-01-01

    The overall objective of the proposed research is to correlate both structural and functional alterations in cells and tissues of the lung brought about by exposure to fluidized bed combustion and fixed bed gasification effluents and reagent grade oxides of metals known to be associated with coal combustion gasification. Projected milestones are described. Progress during the first year in setting up aerosol exposure facilities, intratracheal instillations, pulmonary mechanics, and morphometric examinations is reported. (DMC)

  16. American Cultural History History 390

    E-Print Network [OSTI]

    Fletcher, Robin

    1 American Cultural History History 390 Consider Resources Primary Resources: diaries, letters. popular), theses, the Web Check subject guide under: Research by Subject History by Region American collection unless stated. Album of American History E178 .A2 A (5 volumes; Stauffer ­ Books) Columbia

  17. Central American electrical interconnection

    SciTech Connect (OSTI)

    Not Available

    1988-12-01

    A technical cooperation grant of $2.25 million, designed to strengthen the capacity of Central American countries to operate their regional interconnected electrical system, was announced by the Inter-American Development Bank (IDB). The grant, extended from the banks Fund for Special Operations, will help improve the capacity of the regions electric power companies to achieve economical, safe operation of the interconnected electric power systems. The funds will also be used to finance regional studies of the accords, procedures, regulations, and supervisory mechanisms for the system, as well as program development and data bases.

  18. Fireclimate interactions in the American West since 1400 CE Valerie Trouet,1

    E-Print Network [OSTI]

    Stephens, Scott L.

    Trouet,1 Alan H. Taylor,2 Eugene R. Wahl,3 Carl N. Skinner,4 and Scott L. Stephens5 Received 6 November in the American West that needs to be accounted for in fire models. Citation: Trouet, V., A. H. Taylor, E. R. Wahl of the American West are generally associated with drought [Heyerdahl et al., 2002; Swetnam, 1993; Taylor et al

  19. MRI of the lung using hyperpolarized He-3 at very low magnetic field (3 mT)

    E-Print Network [OSTI]

    Bidinosti, C P; Tastevin, G; Vignaud, A; Nacher, P J

    2004-01-01

    Optical pumping of He-3 produces large (hyper) nuclear-spin polarizations independent of the magnetic resonance imaging (MRI) field strength. This allows lung MRI to be performed at reduced fields with many associated benefits, such as lower tissue susceptibility gradients and decreased power absorption rates. Here we present results of 2D imaging as well as accurate 1D gas diffusion mapping of the human lung using He-3 at very low field (3 mT). Furthermore, measurements of transverse relaxation in zero applied gradient are shown to accurately track pulmonary oxygen partial pressure, opening the way for novel imaging sequences.

  20. American Disabilities Act

    Broader source: Energy.gov [DOE]

    The Americans with Disabilities Act prohibits private employers, state and local governments, employment agencies and labor unions from discriminating against qualified individuals with disabilities in job application procedures, hiring, firing, advancement, compensation, job training, and other terms, conditions, and privileges of employment.

  1. Whole Slide Image Analysis Quantification using Aperio Digital Imaging in a Mouse Lung Metastasis Ronne L. Surface2

    E-Print Network [OSTI]

    Zhou, Yaoqi

    Whole Slide Image Analysis Quantification using Aperio Digital Imaging in a Mouse Lung Metastasis quantitate metastatic mouse lung tumors in a lung section using a H&E stain. Lung sections from a mouse lung of view from each slide representing a whole lung lobe with multiple lung metastases was selected

  2. Arsenic methylation and lung and bladder cancer in a case-control study in northern Chile

    SciTech Connect (OSTI)

    Melak, Dawit; Ferreccio, Catterina; Kalman, David; Parra, Roxana; Acevedo, Johanna; Pérez, Liliana; Cortés, Sandra; Smith, Allan H.; Yuan, Yan; Liaw, Jane; Steinmaus, Craig

    2014-01-15

    In humans, ingested inorganic arsenic is metabolized to monomethylarsenic (MMA) then to dimethylarsenic (DMA), although this process is not complete in most people. The trivalent form of MMA is highly toxic in vitro and previous studies have identified associations between the proportion of urinary arsenic as MMA (%MMA) and several arsenic-related diseases. To date, however, relatively little is known about its role in lung cancer, the most common cause of arsenic-related death, or about its impacts on people drinking water with lower arsenic concentrations (e.g., < 200 ?g/L). In this study, urinary arsenic metabolites were measured in 94 lung and 117 bladder cancer cases and 347 population-based controls from areas in northern Chile with a wide range of drinking water arsenic concentrations. Lung cancer odds ratios adjusted for age, sex, and smoking by increasing tertiles of %MMA were 1.00, 1.91 (95% confidence interval (CI), 0.99–3.67), and 3.26 (1.76–6.04) (p-trend < 0.001). Corresponding odds ratios for bladder cancer were 1.00, 1.81 (1.06–3.11), and 2.02 (1.15–3.54) (p-trend < 0.001). In analyses confined to subjects only with arsenic water concentrations < 200 ?g/L (median = 60 ?g/L), lung and bladder cancer odds ratios for subjects in the upper tertile of %MMA compared to subjects in the lower two tertiles were 2.48 (1.08–5.68) and 2.37 (1.01–5.57), respectively. Overall, these findings provide evidence that inter-individual differences in arsenic metabolism may be an important risk factor for arsenic-related lung cancer, and may play a role in cancer risks among people exposed to relatively low arsenic water concentrations. - Highlights: • Urine arsenic metabolites were measured in cancer cases and controls from Chile. • Higher urine %MMA values were associated with increased lung and bladder cancer. • %MMA-cancer associations were seen at drinking water arsenic levels < 200 ?g/L.

  3. 8/12/08 9:34 AMTo Swim Underwater, Some Insects Carry a Bubble as a Lung -NYTimes.com Page 1 of 2http://www.nytimes.com/2008/08/12/science/12insect.html?_r=1&oref=slogin&ref=science&pagewanted=print

    E-Print Network [OSTI]

    Flynn, Morris R.

    8/12/08 9:34 AMTo Swim Underwater, Some Insects Carry a Bubble as a Lung - NYTimes.com Page 1 of 2=slogin&ref=science&pagewanted=print August 12, 2008 Come Up for Air? Not These Insects, Which Carry a Bubble as a Lung By KENNETH CHANG winter. "It turns out this bubble functions as an external lung," said John W. M. Bush, an associate

  4. An educator in the landscape : a new identity for American wilderness architecture

    E-Print Network [OSTI]

    Rabitaille, Reilly Paul

    2008-01-01

    This thesis dispenses with the traditional, now nostalgic, "rustic" style typically associated with the American wilderness, in favor of proposing a new identity - that of Educator in the Landscape. By blending bio-technology ...

  5. Rape Victimization and High Risk Sexual Behaviors: A Longitudinal Study of African-American Adolescent Females

    E-Print Network [OSTI]

    2011-01-01

    Date violence and date rape among adolescents: Associations31. Wingood GM, DiClemente RJ. Rape among African-Americanand white American women’s rape. J Social Issues. 1992;48:

  6. Working in Indian Country: Building Successful Business Relationships with American Indian Tribes Workshop

    Broader source: Energy.gov [DOE]

    Sponsored by the Association on American Indian Affairs, this one-day conference is for federal, state, and local government officials and business leaders who have a need to develop working relationships with tribes and organizations.

  7. Working in Indian Country: Building Successful Business Relationships with American Indian Tribes Workshop

    Broader source: Energy.gov [DOE]

    Sponsored by the Association on American Indian Affairs, this one-day conference is for federal, state, and local government officials and business leaders who have a need to develop working...

  8. Characterization of Lung Tissues using Liquid-Crystal Tunable Filter and Hyperspectral Imaging System

    E-Print Network [OSTI]

    Won, Chang-Hee

    Characterization of Lung Tissues using Liquid-Crystal Tunable Filter and Hyperspectral Imaging to characterize lung tissue for detecting emphysematous tissues in lung volume reduction surgery. The system, the spectral signature of healthy lung tissue and simulated smokers lung tissue is obtained and compared

  9. Lung EIT: Should we reconstruct resistivity or conductivity? Bartlomiej Grychtol1

    E-Print Network [OSTI]

    Adler, Andy

    Lung EIT: Should we reconstruct resistivity or conductivity? Bartlomiej Grychtol1 , Andy Adler2 1.grychtol@dkfz.de MOTIVATION: In lung EIT, the quantity of interest is the change in regional air volume in the lungs. However. The model contains two non-conductive objects that represent the lungs. Assuming that lung resistivity

  10. Residential Mobility and Lung Cancer Risk: Data-Driven Exploration Using Internet Sources

    SciTech Connect (OSTI)

    Yoon, Hong-Jun; Tourassi, Georgia; Xu, Songhua

    2015-01-01

    Frequent relocation has been linked to health decline, particularly with respect to emotional and psychological wellbeing. In this paper we investigate whether there is an association between frequent relocation and lung cancer risk. For the initial investigation we leverage two online data sources to collect cancer and control subjects using web crawling and tailored text mining. The two data sources share different strengths and weaknesses in terms of the amount of detail, population representation, and sample size. One data source includes online obituaries. The second data source includes augmented LinkedIn profiles. For each data source, the subjects spatiotemporal history is reconstructed from the available information provided in the obituaries and from the education and work experience provided in the LinkedIn profiles. The study shows that lung cancer subjects have higher mobility frequency than the control group. This trend is consistent for both data sources.

  11. American Journal of Primatology 68:812824 (2006) RESEARCH ARTICLE

    E-Print Network [OSTI]

    French, Jeffrey A.

    2006-01-01

    neurotransmitter serotonin (5-HT) contributes to individual differences in impulsive behavior in humans suicide attempts in humans [Asberg et al., 1976], human and primate impulsive aggression [Higley et alAmerican Journal of Primatology 68:812­824 (2006) RESEARCH ARTICLE Serotonin Function Is Associated

  12. Method and apparatus for measuring lung density by Compton backscattering

    DOE Patents [OSTI]

    Loo, Billy W. (Oakland, CA); Goulding, Frederick S. (Lafayette, CA)

    1991-01-01

    The density of the lung of a patient suffering from pulmonary edema is monitored by irradiating the lung by a single collimated beam of monochromatic photons and measuring the energies of photons Compton backscattered from the lung by a single high-resolution, high-purity germanium detector. A compact system geometry and a unique data extraction scheme are utilized to monimize systematic errors due to the presence of the chestwall and multiple scattering.

  13. A System for Open-Access 3 He Human Lung

    E-Print Network [OSTI]

    Walsworth, Ronald L.

    A System for Open-Access 3 He Human Lung Imaging at Very Low Field I.C. RUSET,1 L.L. TSAI,2,3 R describe a prototype system built to allow open-access very-low-field MRI of human lungs using laser images of human lungs. We include discussion on challenges unique to imaging at 50­200 kHz, including

  14. Method and apparatus for measuring lung density by Compton backscattering

    DOE Patents [OSTI]

    Loo, B.W.; Goulding, F.S.

    1988-03-11

    The density of the lung of a patient suffering from pulmonary edema is monitored by irradiating the lung by a single collimated beam of monochromatic photons and measuring the energies of photons compton back-scattered from the lung by a single high-resolution, high-purity germanium detector. A compact system geometry and a unique data extraction scheme are utilized to minimize systematic errors due to the presence of the chestwall and multiple scattering. 11 figs., 1 tab.

  15. The American Recovery

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankADVANCEDInstallers/ContractorsPhotovoltaics »TanklessResearchEnergy2 DOE Hydrogen12TheAmerican

  16. Cell Motility and Deformability in the Pathogenesis of Lung Cancer

    E-Print Network [OSTI]

    Pagano, Paul Carmelo

    2015-01-01

    and increased lung metastasis in NOD/SCID mice. Arch BiochemqPCR analysis Pathogen-free NOD-SCID gamma (NSG) mice were

  17. Autophagy Is Required for Glucose Homeostasis and Lung Tumor Maintenance

    E-Print Network [OSTI]

    Karsli-Uzunbas, Gizem

    Macroautophagy (autophagy hereafter) recycles intracellular components to sustain mitochondrial metabolism that promotes the growth, stress tolerance, and malignancy of lung cancers, suggesting that autophagy inhibition ...

  18. Toward A Quantitative Understanding of Gas Exchange in the Lung

    E-Print Network [OSTI]

    Chang, Yulin V

    2010-01-01

    In this work we present a mathematical framework that quantifies the gas-exchange processes in the lung. The theory is based on the solution of the one-dimensional diffusion equation on a simplified model of lung septum. Gases dissolved into different compartments of the lung are all treated separately with physiologically important parameters. The model can be applied in magnetic resonance of hyperpolarized xenon for quantification of lung parameters such as surface-to-volume ratio and the air-blood barrier thickness. In general this model provides a description of a broad range of biological exchange processes that are driven by diffusion.

  19. Sex-specific differences in hyperoxic lung injury in mice: Implications for acute and chronic lung disease in humans

    SciTech Connect (OSTI)

    Lingappan, Krithika, E-mail: lingappa@bcm.edu [Department of Pediatrics, Section of Neonatology, Texas Children's Hospital, Baylor College of Medicine, 1102 Bates Avenue, MC: FC530.01, Houston, TX 77030 (United States); Jiang, Weiwu; Wang, Lihua; Couroucli, Xanthi I. [Department of Pediatrics, Section of Neonatology, Texas Children's Hospital, Baylor College of Medicine, 1102 Bates Avenue, MC: FC530.01, Houston, TX 77030 (United States); Barrios, Roberto [Department of Pathology and Genomic Medicine, The Methodist Hospital Physician Organization, 6565 Fannin Street, Suite M227, Houston, TX 77030 (United States); Moorthy, Bhagavatula [Department of Pediatrics, Section of Neonatology, Texas Children's Hospital, Baylor College of Medicine, 1102 Bates Avenue, MC: FC530.01, Houston, TX 77030 (United States)

    2013-10-15

    Sex-specific differences in pulmonary morbidity in humans are well documented. Hyperoxia contributes to lung injury in experimental animals and humans. The mechanisms responsible for sex differences in the susceptibility towards hyperoxic lung injury remain largely unknown. In this investigation, we tested the hypothesis that mice will display sex-specific differences in hyperoxic lung injury. Eight week-old male and female mice (C57BL/6J) were exposed to 72 h of hyperoxia (FiO{sub 2} > 0.95). After exposure to hyperoxia, lung injury, levels of 8-iso-prostaglandin F{sub 2} alpha (8-iso-PGF 2?) (LC–MS/MS), apoptosis (TUNEL) and inflammatory markers (suspension bead array) were determined. Cytochrome P450 (CYP)1A expression in the lung was assessed using immunohistochemistry and western blotting. After exposure to hyperoxia, males showed greater lung injury, neutrophil infiltration and apoptosis, compared to air-breathing controls than females. Pulmonary 8-iso-PGF 2? levels were higher in males than females after hyperoxia exposure. Sexually dimorphic increases in levels of IL-6 (F > M) and VEGF (M > F) in the lungs were also observed. CYP1A1 expression in the lung was higher in female mice compared to males under hyperoxic conditions. Overall, our results support the hypothesis that male mice are more susceptible than females to hyperoxic lung injury and that differences in inflammatory and oxidative stress markers contribute to these sex-specific dimorphic effects. In conclusion, this paper describes the establishment of an animal model that shows sex differences in hyperoxic lung injury in a temporal manner and thus has important implications for lung diseases mediated by hyperoxia in humans. - Highlights: • Male mice were more susceptible to hyperoxic lung injury than females. • Sex differences in inflammatory markers were observed. • CYP1A expression was higher in females after hyperoxia exposure.

  20. New American Home 2009 (Brochure)

    SciTech Connect (OSTI)

    Not Available

    2008-12-01

    This brochure details the New American Home 2009, which demonstrates the use of innovative building materials, cutting-edge design, and the latest construction techniques.

  1. Bruce Walcheck: Role of neutrophils in acute lung injury, bacterial lung infection, and sepsis (cell based assays and in vivo studies in mice).

    E-Print Network [OSTI]

    Blanchette, Robert A.

    Bruce Walcheck: Role of neutrophils in acute lung injury, bacterial lung infection, and sepsis, eosinophils, and macrophages in the ( ) oapplie lungs (cell based assays and in vivo studies in mice) Alice). Mike Murtaugh: Pathogenesis of lung inflammation during bacterial and viral pneumonia (cell based

  2. Lung Cancer: A Classic Example of Tumor Escape and Progression While Providing Opportunities for Immunological Intervention

    E-Print Network [OSTI]

    2012-01-01

    of lung cancer,” Clinical Cancer Research, vol. 4, no. 7,pathogenesis of lung cancer,” Annual Review of Physiology,immunoreac- tivity in lung cancer: yet another player in the

  3. Physiological and Computed Tomographic Predictors of Outcome from Lung Volume Reduction Surgery

    E-Print Network [OSTI]

    Physiological and Computed Tomographic Predictors of Outcome from Lung Volume Reduction Surgery: Previous investigations have identified several potential predictors of outcomes from lung volume reduction: To identify objective radiographic and physiological indices of lung disease that have prognostic value

  4. Lung Extraction, Lobe Segmentation and Hierarchical Region Assessment for Quantitative Analysis on High

    E-Print Network [OSTI]

    Lung Extraction, Lobe Segmentation and Hierarchical Region Assessment for Quantitative Analysis Care Division, Brigham and Women's Hospital, Boston, MA Abstract. Regional assessment of lung disease specific to different lung regions on high resolution computed tomography (HRCT) datasets. We present

  5. Opportunities and Inaudibilities: Asian American Internet Musicians

    E-Print Network [OSTI]

    Regullano, Eileen

    2015-01-01

    60–73. Spooner, Tom. “Asian-Americans and the Internet. ”Pew Research Center’s Internet & American Life Project.americans-and-the-internet/. Timothy DeLaGhetto Dog Joke. ,

  6. Dose impact in radiographic lung injury following lung SBRT: Statistical analysis and geometric interpretation

    SciTech Connect (OSTI)

    Yu, Victoria; Kishan, Amar U.; Cao, Minsong; Low, Daniel; Lee, Percy; Ruan, Dan

    2014-03-15

    Purpose: To demonstrate a new method of evaluating dose response of treatment-induced lung radiographic injury post-SBRT (stereotactic body radiotherapy) treatment and the discovery of bimodal dose behavior within clinically identified injury volumes. Methods: Follow-up CT scans at 3, 6, and 12 months were acquired from 24 patients treated with SBRT for stage-1 primary lung cancers or oligometastic lesions. Injury regions in these scans were propagated to the planning CT coordinates by performing deformable registration of the follow-ups to the planning CTs. A bimodal behavior was repeatedly observed from the probability distribution for dose values within the deformed injury regions. Based on a mixture-Gaussian assumption, an Expectation-Maximization (EM) algorithm was used to obtain characteristic parameters for such distribution. Geometric analysis was performed to interpret such parameters and infer the critical dose level that is potentially inductive of post-SBRT lung injury. Results: The Gaussian mixture obtained from the EM algorithm closely approximates the empirical dose histogram within the injury volume with good consistency. The average Kullback-Leibler divergence values between the empirical differential dose volume histogram and the EM-obtained Gaussian mixture distribution were calculated to be 0.069, 0.063, and 0.092 for the 3, 6, and 12 month follow-up groups, respectively. The lower Gaussian component was located at approximately 70% prescription dose (35 Gy) for all three follow-up time points. The higher Gaussian component, contributed by the dose received by planning target volume, was located at around 107% of the prescription dose. Geometrical analysis suggests the mean of the lower Gaussian component, located at 35 Gy, as a possible indicator for a critical dose that induces lung injury after SBRT. Conclusions: An innovative and improved method for analyzing the correspondence between lung radiographic injury and SBRT treatment dose has been demonstrated. Bimodal behavior was observed in the dose distribution of lung injury after SBRT. Novel statistical and geometrical analysis has shown that the systematically quantified low-dose peak at approximately 35 Gy, or 70% prescription dose, is a good indication of a critical dose for injury. The determined critical dose of 35 Gy resembles the critical dose volume limit of 30 Gy for ipsilateral bronchus in RTOG 0618 and results from previous studies. The authors seek to further extend this improved analysis method to a larger cohort to better understand the interpatient variation in radiographic lung injury dose response post-SBRT.

  7. Preparation of Pulmonary SMC Pulmonary smooth muscle cells are isolated from ten 6-day neonatal rat lungs.

    E-Print Network [OSTI]

    Mecham, Robert

    lungs. The lungs are dissected with the trachea still attached and placed in Puck's saline A solution

  8. Lienert named American Welding Society Fellow

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Lienert named American Welding Society Fellow November 29, 2012 Thomas J. Lienert of the Lab's Metallurgy group was inducted into the American Welding Society's 2012 Class of...

  9. Weatherization Formula Grants - American Recovery and Reinvestment...

    Energy Savers [EERE]

    Weatherization Formula Grants - American Recovery and Reinvestment Act (ARRA) Weatherization Formula Grants - American Recovery and Reinvestment Act (ARRA) U.S. Department of...

  10. NORTH AMERICAN ELECTRIC RELIABILITY COUNCIL: Preliminary Disturbance...

    Energy Savers [EERE]

    Report More Documents & Publications North American Electric Reliability Council Power Outage Update North American Electric Reliability Council Outage Announcement Electric System...

  11. Energy Innovation: Green Button Initiative Empowering Americans...

    Energy Savers [EERE]

    Energy Innovation: Green Button Initiative Empowering Americans to Save Energy and Money Energy Innovation: Green Button Initiative Empowering Americans to Save Energy and Money...

  12. Chinese and Chinese American Life-Writing

    E-Print Network [OSTI]

    Cheung, KK

    2015-01-01

    The Chinaman Pacific: Must a Chinese American Critic ChooseAn Anthology of Ancient Chinese Poetry (??????) (Shanghai,The Woman Warrior and the Chinese-American Autobiographical

  13. Lung Toxicity and Mutagenicity of Emissions From Heavy-Duty Compressed...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Lung Toxicity and Mutagenicity of Emissions From Heavy-Duty Compressed Natural Gas (CNG)-Powered Vehicles Lung Toxicity and Mutagenicity of Emissions From Heavy-Duty Compressed...

  14. A Systematic Analysis of Epigenetic Genes across Different Stages of Lung Adenocarcinoma Akshay Desai1

    E-Print Network [OSTI]

    Zhou, Yaoqi

    A Systematic Analysis of Epigenetic Genes across Different Stages of Lung Adenocarcinoma Akshay across different stages of lung adenocarcinoma (LUAD). Method: An integrative system biology approach

  15. Lung Cancer (2005) 47, 41--47 Improving the specificity of fluorescence

    E-Print Network [OSTI]

    Duin, Robert P.W.

    2005-01-01

    Lung Cancer (2005) 47, 41--47 Improving the specificity of fluorescence bronchoscopy spectroscopy; Lung cancer; Bronchoscopy Summary Detection of malignancies of the bronchial tree in an early

  16. Central American update

    SciTech Connect (OSTI)

    Hodgson, S.F.

    1987-07-01

    The Central American Energy Resources Project is designed to help the countries of Honduras, Costa Rica, El Salvador, Guatemala, and Panama develop their geothermal resources. Auxiliary project goals are to increase economic development and employment in Central America; to provide a scientific basis for the private sector to develop natural resources; and to provide scientific training to in-country scientists, engineers, and technicians. The energy resources project began in March 1985. The progress being made in El Salvador (production well logging and geophysical operations), Panama (site selection for the first temperature-gradient well), and Honduras (well drilling of temperature-gradient wells) is summarized.

  17. Central American resource studies

    SciTech Connect (OSTI)

    Van Eeckhout, E.; Laughlin, A.W.

    1989-01-01

    Los Alamos National Laboratory has been working with five Central American countries to assist in the development of their energy and mineral resources. Since 1985, mineral resources in Costa Rica, peat resources in Costa Rica and Panama, geothermal energy resources in Honduras and Guatemala, and geothermal field development in El Salvador and Costa Rica have been topics of study. This paper presents an overview of this work -- within these proceedings are papers that deal with specific aspects of each topic, and these will be duly noted. 15 refs., 4 figs.

  18. American Chemical Society Fellow

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 OutreachProductswsicloudwsiclouddenDVA N C E D B L O O D S TAPropane TexasAmbipolarXunamed as American

  19. Investigating the initiation and progression of small cell lung cancer

    E-Print Network [OSTI]

    Brauneis, Alison Dooley

    2011-01-01

    Small cell lung cancer (SCLC) comprises 18% of all lung cancer cases and is an aggressive disease with a five-year survival rate of less than 5%, mainly due to the advanced nature of the disease at the time of diagnosis. ...

  20. Clean Cities: North Dakota Clean Cities coalition

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    Clean Cities. Moffitt is the communications director for the Clean Fuel & Vehicle Technology program of the American Lung Association of the Upper Midwest. He joined the...

  1. Lisa Thurstin

    Broader source: Energy.gov [DOE]

    Lisa Thurstin is the coordinator for the Twin Cities Clean Cities coalition, which is based out of the American Lung Association of the Upper Midwest.

  2. Lung tissue engineering : in vitro synthesis of lung tissue from neonatal and fetal rat lung cells cultured in a three-dimensional collagen matrix

    E-Print Network [OSTI]

    Chen, Patty P., 1981-

    2004-01-01

    The focus of this study was to investigate the histology of tissue formed when fetal (16-20 days gestation) and neonatal (2 days old) rat lung cells were grown in a collagen-glycosaminoglycan scaffold. This project employed ...

  3. Thinking American, Working American, Playing American Folk Dance in Chicago, 1890-1940 

    E-Print Network [OSTI]

    Herzogenrath, Jessica

    2014-07-23

    for the consideration of folk dance as an integral part of the physical education of children and young women as well as its function as an element of defining American-ness in both higher education and social settlements. Second, the dissertation demonstrates...

  4. Serum Amyloid A as a Predictive Marker for Radiation Pneumonitis in Lung Cancer Patients

    SciTech Connect (OSTI)

    Wang, Yu-Shan [Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China) [Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China); Department of Animal Science, National Ilan University, Ilan, Taiwan (China); Chang, Heng-Jui [Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China)] [Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China); Chang, Yue-Cune [Department of Mathematics, Tamkang University, Taipei, Taiwan (China)] [Department of Mathematics, Tamkang University, Taipei, Taiwan (China); Huang, Su-Chen; Ko, Hui-Ling; Chang, Chih-Chia [Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China)] [Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China); Yeh, Yu-Wung; Jiang, Jiunn-Song [Department of Chest Medicine, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China)] [Department of Chest Medicine, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China); Lee, Cheng-Yen; Chi, Mau-Shin [Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China)] [Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China); Chi, Kwan-Hwa, E-mail: M006565@ms.skh.org.tw [Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China) [Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China); Institute of Radiation Science and School of Medicine, National Yang-Ming University, Taipei, Taiwan (China)

    2013-03-01

    Purpose: To investigate serum markers associated with radiation pneumonitis (RP) grade ?3 in patients with lung cancer who were treated with radiation therapy. Methods and Materials: Pretreatment serum samples from patients with stage Ib-IV lung cancer who developed RP within 1 year after radiation therapy were analyzed to identify a proteome marker able to stratify patients prone to develop severe RP by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS). Dosimetric parameters and 3 biological factors were compared. Results: Serum samples from 16 patients (28%) with severe RP (grade 3-4) and 42 patients (72%) with no or mild RP (grade 0-2) were collected for analysis. All patients received a median of 54 Gy (range, 42-70 Gy) of three-dimensional conformal radiation therapy with a mean lung dose (MLD) of 1502 cGy (range, 700-2794 cGy). An m/z peak of 11,480 Da was identified by SELDI-TOF-MS, and serum amyloid A (SAA) was the primary splitter serum marker. The receiver operating characteristic area under the curve of SAA (0.94; 95% confidence interval [CI], 0.87-1.00) was higher than those of C-reactive protein (0.83; 95% CI, 0.72-0.94), interleukin-6 (0.79; 95% CI, 0.65-0.94), and MLD (0.57; 95% CI, 0.37-0.77). The best sensitivity and specificity of combined SAA and MLD for predicting RP were 88.9% and 96.0%, respectively. Conclusions: Baseline SAA could be used as an auxiliary marker for predicting severe RP. Extreme care should be taken to limit the lung irradiation dose in patients with high SAA.

  5. A comparison of two lung clearance models based on the dissolution rates of oxidized depleted uranium 

    E-Print Network [OSTI]

    Crist, Kevin Craig

    1983-01-01

    qain inf'ormai. ion on the human risk associated with the inhalation of uranium oxide particles produced when firing anti-tank shells called penetrators, The penetrators are formed from uranium metal rods produced from a raw st'ock of uranium...A CUMRARISON Ul 1MD LUNG CLLARANCE MODEl S BASED ON THE OISSOLLlTION RA1FS OF OXIDIZED DErIETED URANIUM A The" is KEVIN CRAIG CRIST Submitt. ed to the Graduate Co11ege of Texas A 8 M University in parti a1 fu1fi 1 1men t of the requirement...

  6. Single-Session Radiofrequency Ablation of Bilateral Lung Metastases

    SciTech Connect (OSTI)

    Palussiere, Jean, E-mail: palussiere@bergonie.org; Gomez, Fernando; Cannella, Matthieu; Ferron, Stephane; Descat, Edouard [Institut Bergonie, Department of Radiology, Regional Cancer Centre (France); Fonck, Marianne [Institut Bergonie, Department of Digestive Oncology (France); Brouste, Veronique [Institut Bergonie, Clinical and Epidemiological Research Unit (France); Avril, Antoine [Institut Bergonie, Department of Surgery (France)

    2012-08-15

    Purpose: This retrospective study examined the feasibility and efficacy of bilateral lung radiofrequency ablation (RFA) performed in a single session. Methods: From 2002-2009, patients with bilateral lung metastases were treated by RFA, where possible in a single session under general anesthesia with CT guidance. The second lung was punctured only if no complications occurred after treatment of the first lung. Five lung metastases maximum per patient were treated by RFA and prospectively followed. The primary endpoint was the evaluation of acute and delayed complications. Secondary endpoints were calculation of hospitalization duration, local efficacy, median survival, and median time to tumor progression. Local efficacy was evaluated on CT or positron emission tomography (PET) CT. Results: Sixty-seven patients were treated for bilateral lung metastases with RFA (mean age, 62 years). Single-session treatment was not possible in 40 due to severe pneumothoraces (n = 24), bilateral pleural contact (n = 14), and operational exclusions (n = 2). Twenty-seven (41%) received single-session RFA of lesions in both lungs for 66 metastases overall. Fourteen unilateral and four bilateral pneumothoraces occurred (18 overall, 66.7%). Unilateral (n = 13) and bilateral (n = 2) chest tube drainage was required. Median hospitalization was 3 (range, 2-8) days. Median survival was 26 months (95% confidence interval (CI), 19-33). Four recurrences on RFA sites were observed (4 patients). Median time to tumor progression was 9.5 months (95% CI, 4.2-23.5). Conclusions: Although performing single-session bilateral lung RFA is not always possible due to pneumothoraces after RFA of first lung, when it is performed, this technique is safe and effective.

  7. He Lung Imaging in an Open Access, Very-Low-Field Human Magnetic Resonance Imaging System

    E-Print Network [OSTI]

    Walsworth, Ronald L.

    3 He Lung Imaging in an Open Access, Very-Low-Field Human Magnetic Resonance Imaging System R. W. Butler,6 F. W. Hersman,4 and R. L. Walsworth1 The human lung and its functions are extremely sensitive lung restrict sub- jects to lying horizontally. Imaging of human lungs using inhaled laser-polarized 3

  8. COMPUTERS AND BIOMEDICAL RESEARCH 17, 580-589 ( 1984) Multicompartment Model of Lung Dynamics*

    E-Print Network [OSTI]

    Longtin, André

    COMPUTERS AND BIOMEDICAL RESEARCH 17, 580-589 ( 1984) Multicompartment Model of Lung Dynamics* B of the lungs. The lungs are represented by 24 compartments each corresponding to a generation of the Weibel model A. In the model it is assumed that gases are transported in the lungs by convection and diffusion

  9. Differential regulation of RANTES and IL-8 expression in lung adenocarcinoma cells

    E-Print Network [OSTI]

    Boyer, Edmond

    1 Differential regulation of RANTES and IL-8 expression in lung adenocarcinoma cells Corinne expression in lung adenocarcinoma cells HALauthormanuscriptinserm-00143972,version1 HAL author manuscript Lung Cancer 56, 2 (2007) 167-74 #12;2 Summary In lung adenocarcinoma, expression of Regulated upon

  10. Automated Lung Nodule Segmentation Using Dynamic Programming and EM Based Classification

    E-Print Network [OSTI]

    Ahuja, Narendra

    Automated Lung Nodule Segmentation Using Dynamic Programming and EM Based Classification Ning Xua a robust and automated algorithm to segment lung nodules in three dimensional (3D) Computed Tomography (CT nodules but also the nodules attached to lung walls and vessels. Keywords: Lung nodule, Segmentation

  11. Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer

    E-Print Network [OSTI]

    Cai, Long

    Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer, Timothy Anderson6, Norman Gerry7, Joseph Keane4, Marc E Lenburg7 & Jerome S Brody1 Lung cancer smokers with suspicion of lung cancer could be used as a lung cancer biomarker. Using a training set (n

  12. Ultrasound-induced lung hemorrhage: Role of acoustic boundary conditions at the pleural surface

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Ultrasound-induced lung hemorrhage: Role of acoustic boundary conditions at the pleural surface intercostal tissue and lung was evaluated as a possible explanation for the enhanced lung damage the volume of air inspired and expired. The acoustic impedance difference between intercostal tissue and lung

  13. NEURAL PCA NETWORK FOR LUNG OUTLINE RECONSTRUCTION IN VQ SCAN IMAGES

    E-Print Network [OSTI]

    Serpen, Gursel

    NEURAL PCA NETWORK FOR LUNG OUTLINE RECONSTRUCTION IN VQ SCAN IMAGES G. Serpen1 , Ph. D., R. Iyer1 system takes the digitized ventilation-perfusion scan images of lungs as input, identify a template according to the size and shape of the lungs and thereby approximate and reconstruct the outline of the lung

  14. EFFECT OF VELOCITY CONTROL ON KINESTHETIC LUNG TUMOUR LOCALIZATION M. D. Naish1,2,3

    E-Print Network [OSTI]

    Naish, Michael D.

    EFFECT OF VELOCITY CONTROL ON KINESTHETIC LUNG TUMOUR LOCALIZATION M. D. Naish1,2,3 , G. L. Mc precludes manual palpation, making the localization of lung tumours chal- lenging. This paper investigates on stiffness variations of the lung parenchyma. Agar injected into ex vivo porcine lungs produced a model

  15. Automatic Lung Nodule Detection from Chest CT Data Using Geometrical Features: Initial Results

    E-Print Network [OSTI]

    Whelan, Paul F.

    Automatic Lung Nodule Detection from Chest CT Data Using Geometrical Features: Initial Results for automatic lung nodule detection from Chest CT data is proposed. The proposed system includes the methods of lung segmentation and nodule detection from CT data. The algorithm for lung segmentation consists

  16. Respiratory Physiology & Neurobiology 131 (2002) 233243 Relative motion of lung and chest wall promotes uniform

    E-Print Network [OSTI]

    Federspiel, William J.

    2002-01-01

    Respiratory Physiology & Neurobiology 131 (2002) 233­243 Relative motion of lung and chest wall, USA b Artificial Lung Program, Uni6ersity of Pittsburgh, Pittsburgh, PA 15260, USA c Department of lung par- enchyma and effective inspiratory action of the diaphragm, the lungs and chest wall must

  17. Impedance measurements of ex vivo rat lung at different volumes of inflation

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Impedance measurements of ex vivo rat lung at different volumes of inflation Michael L. Oelze that the occurrence of ultrasonically induced lung hemorrhage in rats was directly correlated to the level of lung inflation. In that study, it was hypothesized that the lung could be modeled as two components consisting

  18. Evaluation of a Pumping Assist Lung That Uses a Rotating Fiber Bundle

    E-Print Network [OSTI]

    Federspiel, William J.

    Evaluation of a Pumping Assist Lung That Uses a Rotating Fiber Bundle ROBERT G. SVITEK,* BRIAN J. FRANKOWSKI,* AND WILLIAM J. FEDERSPIEL,*§ A paracorporeal respiratory assist lung (PRAL) is being devel- oped for supplemental gas exchange to allow the native lungs of acute lung failure patients to heal. The device consists

  19. Mesenchymal Nuclear factor I B regulates cell proliferation and epithelial differentiation during lung maturation

    E-Print Network [OSTI]

    Gronostajski, Richard M.

    lung maturation Yu-Chih Hsu a , Jason Osinski a , Christine E. Campbell a , E. David Litwack b , Dan 2011 Accepted 6 April 2011 Available online 13 April 2011 Keywords: NFI-B Lung development Mesenchymal is expressed in both lung mesenchyme and epithelium and mice lacking Nfib have severe lung maturation defects

  20. Lung Cancer (2004) 46, 333--340 High serum YKL-40 level in patients with small

    E-Print Network [OSTI]

    Price, Paul A.

    2004-01-01

    Lung Cancer (2004) 46, 333--340 High serum YKL-40 level in patients with small cell lung cancer May 2004; accepted 6 May 2004 KEYWORDS Small cell lung carcinoma; Tumor invasiveness; YKL-40; HC gp-39 evaluated serum YKL-40 in 131 patients with small cell lung cancer (SCLC). Twenty-two percent

  1. A Novel Laminin E8 Cell Adhesion Site Required for Lung Alveolar Formation In Vitro

    E-Print Network [OSTI]

    A Novel Laminin E8 Cell Adhesion Site Required for Lung Alveolar Formation In Vitro Michelle L,UniversityofVirginia,Charlottesville,Virginia22908 Abstract. Basement membrane-adherent type II alveo- lar cells isolated from lung assemble with a key role in lung alveolar morphogenesis. M ORPHOGENESISof lung alveoli, the functional unit ofbi

  2. Lung squamous cell carcinoma (SCC) is the second most frequent histologic subtype of

    E-Print Network [OSTI]

    Pajarola, Renato B.

    ·Topic Lung squamous cell carcinoma (SCC) is the second most frequent histologic subtype of lung cancer displaying a frequency of 25% among all lung cancers. This subtype is morphologically. The aim of this project is to help model the 3D architecture and shape of human lung squamous cell

  3. Synthetic Lung Tumor Data Sets for Comparison of Volumetric Algorithms1

    E-Print Network [OSTI]

    Bernal, Javier

    Synthetic Lung Tumor Data Sets for Comparison of Volumetric Algorithms1 Adele P. Peskin of synthetic lung tumor data in which synthetic tumors of known volume are embedded in clinical lung computerized tomographic (CT) data in different background settings in the lung. Because the change

  4. Lung Cancer 86 (2014) 7884 Contents lists available at ScienceDirect

    E-Print Network [OSTI]

    Hemminki, Akseli

    2014-01-01

    Lung Cancer 86 (2014) 78­84 Contents lists available at ScienceDirect Lung Cancer journal homepage: www.elsevier.com/locate/lungcan Metastatic sites and survival in lung cancer M. Riihimäkia,b, , A Lung metastasis Brain metastasis Liver metastasis a b s t r a c t Objectives: Population-based data

  5. Level Set based Reconstruction Algorithm for EIT Lung Images: First Clinical Results

    E-Print Network [OSTI]

    Adler, Andy

    Level Set based Reconstruction Algorithm for EIT Lung Images: First Clinical Results Peyman Rahmati of a slow flow inflation pressure-volume manoeuvre in lung healthy and adult lung injury patients. Images conductivity changes in the distribution of lung ventilation using the level set based reconstruction method. 1

  6. Elastin protein levels are a vital modifier affecting normal lung development and susceptibility to emphysema

    E-Print Network [OSTI]

    Mecham, Robert

    Elastin protein levels are a vital modifier affecting normal lung development and susceptibility modifier affecting normal lung development and susceptibility to emphysema. Am J Physiol Lung Cell Mol-induced emphysema is highly variable, and numerous genetic and environmental factors are thought to mitigate lung

  7. TP53 gene mutations of lung cancer patients in upper northern Thailand and environmental risk factors

    E-Print Network [OSTI]

    TP53 gene mutations of lung cancer patients in upper northern Thailand and environmental risk mutations are observed in about 40e70% of lung cancer tissues, and the hot spot codon mu- tations factors that influence TP53 gene mutation in lung cancer patients residing areas with high lung cancer

  8. The Bases Are Loaded: American Indians and American Studies

    E-Print Network [OSTI]

    Meland, Carter; Bauerkemper, Joseph; Howe, LeAnne; Stark, Heidi

    2006-03-01

    with the perspectives of American Indian studies. In general, as Nikhil Pal Singh notes, current cultural discourse "counterposes multiculturalism and universalism as principal, opposed terms in the culture wars."6 Singh elaborates that this oppo sition "determines... with the perspectives of American Indian studies. In general, as Nikhil Pal Singh notes, current cultural discourse "counterposes multiculturalism and universalism as principal, opposed terms in the culture wars."6 Singh elaborates that this oppo sition "determines...

  9. Multi-scale analysis of lung computed tomography images

    E-Print Network [OSTI]

    Gori, I; Fantacci, M E; Martinez, A Preite; Retico, A; De Mitri, I; Donadio, S; Fulcheri, C; Gargano, G; Magro, R; Santoro, M; Stumbo, S; 10.1088/1748-0221/2/09/P09007

    2009-01-01

    A computer-aided detection (CAD) system for the identification of lung internal nodules in low-dose multi-detector helical Computed Tomography (CT) images was developed in the framework of the MAGIC-5 project. The three modules of our lung CAD system, a segmentation algorithm for lung internal region identification, a multi-scale dot-enhancement filter for nodule candidate selection and a multi-scale neural technique for false positive finding reduction, are described. The results obtained on a dataset of low-dose and thin-slice CT scans are shown in terms of free response receiver operating characteristic (FROC) curves and discussed.

  10. LGBT African-American Individuals and African-American Same-Sex Couples

    E-Print Network [OSTI]

    Gates, Gary J.; Kastanis, Angel

    2013-01-01

    of African-American same-sex couples are raising children.African-American same-sex couples raising children reportAfrican- American different-sex couples ($47,300 vs. $

  11. The effects of neighborhood environments on the level of physical activity among older african american women in Texas 

    E-Print Network [OSTI]

    Shin, Woo Hwa

    2009-05-15

    The older African American women living Texas fall into one of the most inactive population segments. Recently, the importance of socio-ecological models on human health behavior and more complex associations between ...

  12. Our Relationship, My Academia: Historical and Hegemonic Implications Imbuing Academically Successful African American Women from Single-mothered Families 

    E-Print Network [OSTI]

    Johnson, Johnitha Watkins

    2013-12-04

    nurturing Mother- biological female parent who concurrently assumes maternal nurturing Negro- a late 19th century term used to define U. S. born Americans of African descent; also used as a term of reproach given its association with racial epithets...

  13. American Indian Policy and Relevant DOE and Executive Orders...

    Office of Environmental Management (EM)

    Tribal Programs American Indian Policy and Relevant DOE and Executive Orders American Indian Policy and Relevant DOE and Executive Orders Over the course of American history,...

  14. Dr Eugenio Carminati Associate Professor (Structural Geology)

    E-Print Network [OSTI]

    Dr Eugenio Carminati Associate Professor (Structural Geology) room 216 ph: +39 0649914950 fax a degree in Geological Sciences at the University of Milano with a thesis in Structural Geology. I achieved. I'm fellow of the Geological Society of Italy and of the American Geophysical union. Between 2004

  15. Geothermal energy for American Samoa

    SciTech Connect (OSTI)

    Not Available

    1980-03-01

    The geothermal commercialization potential in American Samoa was investigated. With geothermal energy harnessed in American Samoa, a myriad of possibilities would arise. Existing residential and business consumers would benefit from reduced electricity costs. The tuna canneries, demanding about 76% of the island's process heat requirements, may be able to use process heat from a geothermal source. Potential new industries include health spas, aquaculture, wood products, large domestic and transhipment refrigerated warehouses, electric cars, ocean nodule processing, and a hydrogen economy. There are no territorial statutory laws of American Samoa claiming or reserving any special rights (including mineral rights) to the territorial government, or other interests adverse to a land owner, for subsurface content of real property. Technically, an investigation has revealed that American Samoa does possess a geological environment conducive to geothermal energy development. Further studies and test holes are warranted.

  16. Idaho_AmericanFallsRockland

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Wind Power - Idaho Wind Anemometer Loan Program American FallsRockland Site 106 Latitude: N. 42 deg. 40.682' Longitude: W. 112 deg. 46.325' Elevation: 6579' Anemometer Height: 20...

  17. The New American Home 2011

    SciTech Connect (OSTI)

    2010-12-01

    The New American Home® is built annually as a showcase home for the International Builders’ Show® to demonstrate innovative technologies, construction techniques, products, and design trends for the homebuilding industry to use in any new or remodeled home.

  18. Emerging Latin American air quality regulation

    SciTech Connect (OSTI)

    Hosmer, A.W.; Vitale, E.M.; Guerrero, C.R.; Solorzano-Vincent, L.

    1998-12-31

    Latin America is the most urbanized region in the developing world. In recent years, significant economic growth has resulted in population migration from rural areas to urban centers, as well as in a substantial rise in the standard of living within the Region. These changes have impacted the air quality of Latin American countries as increased numbers of industrial facilities and motor vehicles release pollutants into the air. With the advent of new free trade agreements such as MERCOSUR and NAFTA, economic activity and associated pollutant levels can only be expected to continue to expand in the future. In order to address growing air pollution problems, many Latin America countries including Argentina, Brazil, Chile, Columbia, Costa Rica, and Mexico have passed, or will soon pass, new legislation to develop and strengthen their environmental frameworks with respect to air quality. As a first step toward understanding the impacts that this increased environmental regulation will have, this paper will examine the regulatory systems in six Latin American countries with respect to ambient air quality and for each of these countries: review a short history of the air quality problems within the country; outline the legal and institutional framework including key laws and implementing institutions; summarize in brief the current status of the country in terms of program development and implementation; and identify projected future trends. In addition, the paper will briefly review the international treaties that have bearing on Latin American air quality. Finally, the paper will conclude by identifying and exploring emerging trends in individual countries and the region as a whole.

  19. African Americans and the Spanish-American War and Philippine Insurrection: Military Participation, Recognition, and Memory, 1898-1904

    E-Print Network [OSTI]

    Russell, Timothy Dale

    2013-01-01

    and the Spanish American War. ” Indiana Magazine of History,the Spanish American War, The Sixth Virginia Volunteers. ”African Americans and the War Against Spain. ” The North

  20. Excerpt from Dead Stars: American and Philippine Literary Perspectives on the American Colonization of the Philippines

    E-Print Network [OSTI]

    McMahon, Jennifer M.

    2011-01-01

    Dead Stars: American and Philippine Literary Perspectives onthe American Colonization of the Philippines (Quezon City:University of the Philippines Press, 2011). Published with

  1. Tumour microenvironment interactions of small cell lung cancer. 

    E-Print Network [OSTI]

    Hodkinson, Philip Simon

    2009-01-01

    Small cell lung cancer (SCLC) is characterised by rapid growth, early metastatic spread and poor long-term survival. The tumour is initially sensitive to chemotherapy and thus objective response rates are high. Unfortunately, ...

  2. Functional lung imaging in humans using Positron Emission Tomography

    E-Print Network [OSTI]

    Layfield, Dominick, 1971-

    2003-01-01

    This thesis deals with a method of functional lung imaging using Positron Emission Tomography (PET). In this technique, a radioactive tracer, nitrogen-13, is dissolved in saline solution, and injected into a peripheral ...

  3. Selectins Mediate Small Cell Lung Cancer Systemic Metastasis

    E-Print Network [OSTI]

    Heidemann, Franziska

    Metastasis formation is the major reason for the extremely poor prognosis in small cell lung cancer (SCLC) patients. The molecular interaction partners regulating metastasis formation in SCLC are largely unidentified, ...

  4. HIF-2? deletion promotes Kras-driven lung tumor development

    E-Print Network [OSTI]

    Jacks, Tyler E.

    Non-small cell lung cancer (NSCLC) is the leading cause of cancer deaths worldwide. The oxygen-sensitive hypoxia inducible factor (HIF) transcriptional regulators HIF-1? and HIF-2? are overexpressed in many human NSCLCs, ...

  5. LOS ALAMOS, New Mexico, December 15, 2011-The American Association...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    such projects as the improved efficiency of plant photosynthesis, advances in - 2 - algae production and harvesting, and understanding the biochemical and biophysical processes...

  6. Virtual Mentor American Medical Association Journal of Ethics

    E-Print Network [OSTI]

    Fujimura, Joan

    ). These "genetic markers" of human variation are thought to comprise only a tiny proportion, around 0.5 percent allowed researchers interested in human genetic variation to begin to catalogue the range of genetic such as the International Haplotype Mapping Project [1]. These studies of human genetic variation promise to produce new

  7. American Wind Energy Association Offshore WINDPOWER Conference & Exhibition

    Broader source: Energy.gov [DOE]

    AWEA Offshore WINDPOWER 2014 Conference & Exhibition is the largest offshore wind energy event in North America. The conference and exhibition will be held at the Atlantic City Convention...

  8. QER- Comment of American Public Power Association 4

    Office of Energy Efficiency and Renewable Energy (EERE)

    I am not sure these made the record for the QER either, so I am sending them again. Sorry for all the e-mail, but I want to make sure these documents make the record. Thanks, and please enjoy the rest of your Sunday.

  9. QER- Comment of American Wind Energy Association 2

    Broader source: Energy.gov [DOE]

    QER Task Force – Attached please find brief supplemental comments that AWEA would like to submit for your consideration as you continuing drafting the QER.

  10. Sandia Energy - Two Sandia Leaders Elected American Association...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    President of Sandia's California laboratory and leader of the Labs' Energy and Climate PMU), two key members of Sandia National Laboratories' senior leadership team, have been...

  11. QER- Comment of American Public Power Association 3

    Broader source: Energy.gov [DOE]

    Attached are APPA’s comments for the Second public QER meeting. I have tried to submit these before too, so please send me a confirmation e-mail. Thanks in advance for your consideration of my request.

  12. Home Energy Score Program Overview for the American Gas Association...

    Energy Savers [EERE]

    at a standard shingled roof with no insulation on the underside. We also collect how dark the roof is, so this is a number between 0.1 and 1. In the new version we're actually...

  13. COMPOSITES 2006 Convention and Trade Show American Composites Manufacturers Association

    E-Print Network [OSTI]

    . The fundamental material characteris- tics of the panels in tension, compression, flexure and shear are critical undertaken to determine the effect of the material configuration on the material characteris- tics

  14. American Evaluation Association Guiding Principles for Evaluators, 2004 |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based Fuels Research at NRELDepartmentJuneAmerescoEnergyDepartment of Energy

  15. American Bar Association Section on Environment | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION JEnvironmental Jump to:EAand DaltonSolarOpen5AllEnergyAmeriPower LLC Jump to: navigation,Bar

  16. SRS employees raise funds for American Heart Association | National Nuclear

    National Nuclear Security Administration (NNSA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal GasAdministration Medal01 Sandia4) August 20123/%2A en NNSAReference to Mod/%2A en

  17. Comments of the American Public Power Association | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustmentsShirleyEnergyTher i n c i p aDepartment of EnergyofDepartment ofCrowSpace Data isDepartmentthe

  18. American Wind Energy Association AWEA | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION J APPENDIX E LIST OFAMERICA'S FUTURE.EnergyWoodenDateSA JumpSolar PV

  19. American Gas Association (AGA) for DOE Furnace Product Class | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative FuelsofProgram:Y-12 Beta-3AUDITLeslieAlgae BiomassServices »Money |of Energy

  20. American Gas Association Ex Parte Communication | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative FuelsofProgram:Y-12 Beta-3AUDITLeslieAlgae BiomassServices »Money |of EnergyEx

  1. American Gas Association Memorandum Summarizing Ex Parte Communication |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative FuelsofProgram:Y-12 Beta-3AUDITLeslieAlgae BiomassServices »Money |of

  2. Fall 2006 Meeting of theAmerican Statistical Association

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet) Wyoming Dry NaturalPrices1Markets 9,WhyConsumption6 Weekly5 Meeting of the65

  3. Comments of The American Public Power Association | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustmentsShirleyEnergy A plug-in electric vehicle (PEV)Day-June 22, 2015 |AT&T IncNationalDepartmentThe

  4. Fuel Cell Manufacturing: American Energy and Manufacturing Competitive...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Fuel Cell Manufacturing: American Energy and Manufacturing Competitiveness Summit Fuel Cell Manufacturing: American Energy and Manufacturing Competitiveness Summit Presentation on...

  5. The relationship between verve and the academic achievement of African American and European American middle school students 

    E-Print Network [OSTI]

    Hawkins, Torrance N.

    2006-04-12

    between African American and European American students? 2. Is there a significant difference in verve levels of African American male and African American female students in middle school? 3. Is there a significant difference in the academic achievement...

  6. Information Technology: American National Standard for

    E-Print Network [OSTI]

    Information Technology: American National Standard for Information Systems-- Data Format Publication 500-245 Information Technology: American National Standard for Information Systems-- Data Format for the Interchange of Fingerprint, Facial, & Scar Mark & Tattoo (SMT) Information Sponsored by Information Technology

  7. American Valve: Order (2010-CW-1411)

    Broader source: Energy.gov [DOE]

    DOE ordered American Valve, Inc. to pay a $5,000 civil penalty after finding American Valve had failed to certify that certain showerhead models comply with the applicable water conservation standards.

  8. North American Leaders Summit: Energy Deliverables | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    discussions at the North American Leaders Summit, to be held in Guadalajara, Mexico, on August 9-10, 2009. Building on the work of the North American Energy Working...

  9. American Range: Order (2014-CE-23006)

    Broader source: Energy.gov [DOE]

    DOE ordered American Range Corporation to pay a $8,000 civil penalty after finding American Range had failed to certify that certain models of cooking products comply with the applicable energy conservation standards.

  10. Heart Healthy Home Cooking African American Style

    E-Print Network [OSTI]

    Shen, Jun

    Heart Healthy Home Cooking African American Style With Every Heartbeat Is Life #12;#12;Heart Recipe Substitutions for Heart Healthy Cooking at the heart of African American family life and special celebrations. This recipe book brings together many

  11. Information Technology: American National Standard for Information

    E-Print Network [OSTI]

    Information Technology: American National Standard for Information Systems-- Data Format 500-275 Information Technology: American National Standard for Information Systems-- Data Format Coleman, and Patrice Yuh, Editors Sponsored by Information Access Division Information Technology

  12. Information Technology: American National Standard for Information

    E-Print Network [OSTI]

    Information Technology: American National Standard for Information Systems-- Data Format-271 Information Technology: American National Standard for Information Systems-- Data Format for the Interchange Sponsored by Information Access Division Information Technology Laboratory National Institute of Standards

  13. Predictive Factors of Late Radiation Fibrosis: A Prospective Study in Non-Small Cell Lung Cancer

    SciTech Connect (OSTI)

    Mazeron, Renaud [University of Lyon, Centre Leon Berard, Department of Radiation Oncology, Lyon (France); Etienne-Mastroianni, Benedicte [Hopital Louis Pradel, Department of Pneumology, Lyon (France); Perol, David [University of Lyon, Centre Leon Berard, Departement of Public Health, Lyon (France); Arpin, Dominique [Hopital de la Croix-Rousse, Department of Pneumology, Lyon (France); Vincent, Michel [Hopital Saint Luc-Saint Joseph, Department of Pneumology, Lyon (France); Falchero, Lionel [Centre Hospitalier General, Department of Pneumology, Villefranche sur Saone (France); Martel-Lafay, Isabelle; Carrie, Christian [University of Lyon, Centre Leon Berard, Department of Radiation Oncology, Lyon (France); Claude, Line, E-mail: claude@lyon.fnclcc.f [University of Lyon, Centre Leon Berard, Department of Radiation Oncology, Lyon (France)

    2010-05-01

    Purpose: To determine predictive factors of late radiation fibrosis (RF) after conformal radiotherapy (3D-RT) in non-small cell lung cancer (NSCLC). Methods and Materials: Ninety-six patients with Stage IA-IIIB NSCLC were included in a prospective trial. Clinical evaluation, chest X-ray, and pulmonary functional tests including diffusion parameters were performed before and 6 months after radiotherapy. An independent panel of experts prospectively analyzed RF, using Late Effects in Normal Tissues-Subjective, Objective, Management and Analytic scales classification. Logistic regression analysis was performed to identify relationships between clinical, functional, or treatment parameters and incidence of RF. Variations of circulating serum levels of pro-inflammatory (interleukin-6, tumor necrosis factor alpha, tumor growth factor beta1) and anti-inflammatory (interleukin-10) cytokines during 3D-RT were examined to identify correlations with RF. Results: Of the 96 patients included, 72 were evaluable for RF at 6 months. Thirty-seven (51.4%) developed RF (Grade >=1), including six severe RF (Grades 2-3; 8.3%). In univariate analysis, only poor Karnofsky Performance Status and previous acute radiation pneumonitis were associated with RF (p < 0.05). Dosimetric factors (mean lung dose, percentage of lung volume receiving more than 10, 20, 30, 40, and 50 Gy) were highly correlated with RF (p < 0.001). In multivariate analysis, previous acute radiation pneumonitis and dosimetric parameters were significantly correlated with RF occurrence. It was not significantly correlated either with cytokines at baseline or with their variation during 3D-RT. Conclusions: This study confirms the importance of dosimetric parameters to limit the risk of RF. Contrary to acute radiation pneumonitis, RF was not correlated to cytokine variations during 3D-RT.

  14. Figure 6: An MTAH for 11 lung tumor contours generated by MDISC based on area, circularity, and extrusiveness.

    E-Print Network [OSTI]

    California at Los Angeles, University of

    Figure 6: An MTAH for 11 lung tumor contours generated by M­DISC based on area, circularity, and extrusiveness. Figure 7: The CT scanned lung image for image 6 (in Figure 3) with the lung tumor contour

  15. SU-E-J-185: Gated CBCT Imaging for Positioning Moving Lung Tumor in Lung SBRT Treatment

    SciTech Connect (OSTI)

    Li, X; Li, T; Zhang, Y; Burton, S; Karlovits, B; Clump, D; Heron, D; Huq, M

    2014-06-01

    Purpose: Lung stereo-tactic body radiotherapy(SBRT) treatment requires high accuracy of lung tumor positioning during treatment, which is usually accomplished by free breathing Cone-Beam computerized tomography (CBCT) scan. However, respiratory motion induced image artifacts in free breathing CBCT may degrade such positioning accuracy. The purpose of this study is to investigate the feasibility of gated CBCT imaging for lung SBRT treatment. Methods: Six Lung SBRT patients were selected for this study. The respiratory motion of the tumors ranged from 1.2cm to 3.5cm, and the gating windows for all patients were set between 35% and 65% of the respiratory phases. Each Lung SBRT patient underwent free-breathing CBCT scan using half-fan scan technique. The acquired projection images were transferred out for off-line analyses. An In-house semi-automatic algorithm was developed to trace the diaphragm movement from those projection images to acquire a patient's specific respiratory motion curve, which was used to correlate respiratory phases with each projection image. Afterwards, a filtered back-projection algorithm was utilized to reconstruct the gated CBCT images based on the projection images only within the gating window. Results: Target volumes determined by free breathing CBCT images were 71.9%±72% bigger than the volume shown in gated CBCT image. On the contrary, the target volume differences between gated CBCT and planning CT images at exhale stage were 5.8%±2.4%. The center to center distance of the targets shown in free breathing CBCT and gated CBCT images were 9.2±8.1mm. For one particular case, the superior boundary of the target was shifted 15mm between free breathing CBCT and gated CBCT. Conclusion: Gated CBCT imaging provides better representation of the moving lung tumor with less motion artifacts, and has the potential to improve the positioning accuracy in lung SBRT treatment.

  16. The early American motion picture industry: promoting American cultural hegemony 

    E-Print Network [OSTI]

    Wier, Theresa Joanne

    1994-01-01

    For the American motion picture industry, a key period in its development was that which followed World War I until the advent of the techonology of sound film. Film occupied a unique position during this period, as both a product and promoter...

  17. Classification of interstitial lung disease patterns with topological texture features

    E-Print Network [OSTI]

    Huber, Markus B; Leinsinger, Gerda; Ray, Lawrence A; Wismüller, Axel; 10.1117/12.844318

    2010-01-01

    Topological texture features were compared in their ability to classify morphological patterns known as 'honeycombing' that are considered indicative for the presence of fibrotic interstitial lung diseases in high-resolution computed tomography (HRCT) images. For 14 patients with known occurrence of honey-combing, a stack of 70 axial, lung kernel reconstructed images were acquired from HRCT chest exams. A set of 241 regions of interest of both healthy and pathological (89) lung tissue were identified by an experienced radiologist. Texture features were extracted using six properties calculated from gray-level co-occurrence matrices (GLCM), Minkowski Dimensions (MDs), and three Minkowski Functionals (MFs, e.g. MF.euler). A k-nearest-neighbor (k-NN) classifier and a Multilayer Radial Basis Functions Network (RBFN) were optimized in a 10-fold cross-validation for each texture vector, and the classification accuracy was calculated on independent test sets as a quantitative measure of automated tissue characteriza...

  18. 2012 Fellow American Geophysical Union

    E-Print Network [OSTI]

    Kurapov, Alexander

    ) are critical to the intensity of ocean currents, to long- and short-term climate variations, and the health2012 Fellow American Geophysical Union James Moum, professor in the College of Earth, Ocean contributions to our understanding of ocean mixing in coastal, abyssal and Equatorial regimes using innovative

  19. National Museum of American History

    E-Print Network [OSTI]

    Miller, Scott

    National Museum of American History Strategic Plan 2013--2018 #12;Contents Looking Ahead 2 Mission Funding the Plan 12 Coda 15 A Tagline to Remember 16 Milestones 17 Credits 21 Love History. Use History. Make History. #12;Mission Through incomparable collections, rigorous research, and dynamic public

  20. North American Cross-Border

    E-Print Network [OSTI]

    Consumption in USA and Canada 21 Figure 8: Electricity Export as a Fraction of Domestic Consumption in USANorth American Cross-Border Electricity Trade Ian M. Loomis Virginia Center for Coal and Energy ii List of Tables ii List of Figures 1 EXECUTIVE SUMMARY 2 INTRODUCTION 5 ELECTRICITY GENERATION

  1. Developmental expression and glucocorticoid control of the leptin receptor in fetal ovine lung

    E-Print Network [OSTI]

    De Blasio, Miles J.; Boije, Maria; Vaughan, Owen R.; Bernstein, Brett S.; Davies, Katie L.; Plein, Alice; Kempster, Sarah L.; Smith, Gordon C. S.; Charnock-Jones, D. Stephen; Blache, Dominique; Wooding, F. B. Peter; Giussani, Dino A.; Fowden, Abigail L.; Forhead, Alison J.

    2015-08-11

    The effects of endogenous and synthetic glucocorticoids on fetal lung maturation are well-established, although the role of leptin in lung development before birth is unclear. This study examined mRNA and protein levels of the signalling long...

  2. Response and Resistance to NF-?B Inhibitors in Mouse Models of Lung Adenocarcinoma

    E-Print Network [OSTI]

    Xue, Wen

    Lung adenocarcinoma is a leading cause of cancer death worldwide. We recently showed that genetic inhibition of the NF-?B pathway affects both the initiation and the maintenance of lung cancer, identifying this pathway as ...

  3. Spatiotemporal quantification of cell dynamics in the lung following influenza virus infection

    E-Print Network [OSTI]

    Yin, Lu

    Lung injury caused by influenza virus infection is widespread. Understanding lung damage and repair progression post infection requires quantitative spatiotemporal information on various cell types mapping into the tissue ...

  4. Precision-cut lung slices: a novel model for respiratory tract toxicology 

    E-Print Network [OSTI]

    Schwade, Lisa Schier

    1995-01-01

    The lungs are a prominent target organ for numerous types of chemically-induced pathological changes. Current concepts of the pathogenesis of lung injury and repair are derived from in vitro and in vivo investigations. In ...

  5. Major Shifts in the Spatio-Temporal Distribution of Lung Antioxidant Enzymes during Influenza Pneumonia

    E-Print Network [OSTI]

    Yamada, Yoshiyuki

    With the incessant challenge of exposure to the air we breathe, lung tissue suffers the highest levels of oxygen tension and thus requires robust antioxidant defenses. Furthermore, following injury or infection, lung tissue ...

  6. Journal of Biomechanics 40 (2007) 9931001 Pulmonary vascular remodeling in isolated mouse lungs

    E-Print Network [OSTI]

    Chesler, Naomi C.

    2007-01-01

    Journal of Biomechanics 40 (2007) 993­1001 Pulmonary vascular remodeling in isolated mouse lungs­flow relationships in mouse lungs and does so via structural remodeling. They also provide important baseline data

  7. Evaluation of Force Feedback Requirements for Minimally Invasive Lung Tumour Localization

    E-Print Network [OSTI]

    Naish, Michael D.

    Evaluation of Force Feedback Requirements for Minimally Invasive Lung Tumour Localization Greig L describes experiments that were conducted on ex-vivo porcine lung, using artificial tumours, to elucidate

  8. Program restructuring using clustering techniques Chung-Horng Lung a,*, Xia Xu a

    E-Print Network [OSTI]

    Lung, Chung-Horng

    Program restructuring using clustering techniques Chung-Horng Lung a,*, Xia Xu a , Marzia Zaman b. Tel.: +1 613 5202600; fax: +1 613 5205727. E-mail addresses: chlung@sce.carleton.ca (C.-H. Lung

  9. Quantification of Neuroepithelial Bodies and Their Innervation in Fawn-Hooded and Wistar Rat Lungs

    E-Print Network [OSTI]

    Burnstock, Geoffrey

    Quantification of Neuroepithelial Bodies and Their Innervation in Fawn-Hooded and Wistar Rat Lungs neuroendocrine system (DNES) of the lungs, the neuroendocrine cells of which have been shown to express

  10. On Computing Farthest Dominated Locations Hua Lu, Member, IEEE, Man Lung Yiu

    E-Print Network [OSTI]

    Yiu, Man Lung

    1 On Computing Farthest Dominated Locations Hua Lu, Member, IEEE, Man Lung Yiu Abstract--In reality@cs.aau.dk · Man Lung Yiu is with the Department of Computing, Hong Kong Polytechnic University, Hong Kong. E

  11. Smarter Electricity through Argumentation Menelaos Makriyiannis, Tudor Lung, Robert Craven, Francesca Toni and Jack Kelly

    E-Print Network [OSTI]

    Toni, Francesca

    Smarter Electricity through Argumentation Menelaos Makriyiannis, Tudor Lung, Robert Craven101,ft,dk3810}@doc.ic.ac.uk, tudor.lung@gmail.com Abstract--The current, widespread introduction

  12. Reverse Nearest Neighbors Search in Ad-hoc Subspaces Man Lung Yiu

    E-Print Network [OSTI]

    Mamoulis, Nikos

    Reverse Nearest Neighbors Search in Ad-hoc Subspaces Man Lung Yiu Department of Computer Science, H.2.4.h Query processing, H.2.4.k Spatial databases Contact Author: Man Lung Yiu Department

  13. Software Architecture Decomposition Using Attributes Chung-Horng Lung, Xia Xu Marzia Zaman

    E-Print Network [OSTI]

    Lung, Chung-Horng

    Software Architecture Decomposition Using Attributes Chung-Horng Lung, Xia Xu Marzia Zaman in the life cycle. Inspired by Alexander, Andreu, et al. [3] and Lung, et al. [15] presented applications

  14. Extracting k Most Important Groups from Data Efficiently Man Lung Yiu a

    E-Print Network [OSTI]

    Hristidis, Vagelis

    Extracting k Most Important Groups from Data Efficiently Man Lung Yiu a , Nikos Mamoulis b.3 Optimization and Performance Contact Author: Man Lung Yiu #12;1. Introduction Aggregate queries summarize

  15. Lung dosimetry in a linac-MRI radiotherapy unit with a longitudinal magnetic field

    SciTech Connect (OSTI)

    Kirkby, C.; Murray, B.; Rathee, S.; Fallone, B. G. [Department of Medical Physics, Cross Cancer Institute, 11560 University Avenue, Edmonton, Alberta T6G 1Z2 (Canada); Department of Medical Physics, Cross Cancer Institute, Department of Oncology, University of Alberta, 11560 University Avenue, Edmonton, Alberta T6G 1Z2 (Canada); Department of Medical Physics, Cross Cancer Institute, Department of Oncology and Department of Physics, University of Alberta, 11560 University Avenue, Edmonton, Alberta T6G 1Z2 (Canada)

    2010-09-15

    Purpose: There is interest in developing linac-MR systems for MRI-guided radiation therapy. To date, the designs for such linac-MR devices have been restricted to a transverse geometry where the static magnetic field is oriented perpendicular to the direction of the incident photon beam. This work extends possibilities in this field by proposing and examining by Monte Carlo simulations, a probable longitudinal configuration where the magnetic field is oriented in the same direction as the photon beam. Methods: The EGSnrc Monte Carlo (MC) radiation transport codes with algorithms implemented to account for the magnetic field deflection of charged particles were used to compare dose distributions for linac-MR systems in transverse and longitudinal geometries. Specifically, the responses to a 6 MV pencil photon beam incident on water and lung slabs were investigated for 1.5 and 3.0 T magnetic fields. Further a five field lung plan was simulated in the longitudinal and transverse geometries across a range of magnetic field strengths from 0.2 through 3.0 T. Results: In a longitudinal geometry, the magnetic field is shown to restrict the radial spread of secondary electrons to a small degree in water, but significantly in low density tissues such as lung in contrast to the lateral shift in dose distribution seen in the transverse geometry. These effects extend to the patient case, where the longitudinal configuration demonstrated dose distributions more tightly confined to the primary photon fields, which increased dose to the planning target volume (PTV), bettered dose homogeneity within a heterogeneous (in density) PTV, and reduced the tissue interface effects associated with the transverse geometry. Conclusions: Dosimetry issues observed in a transverse linac-MR geometry such as changes to the depth dose distribution and tissue interface effects were significantly reduced or eliminated in a longitudinal geometry on a representative lung plan. Further, an increase in dose to the PTV, resulting from the magnetic field confining electrons to the forward direction, shows potential for a reduction in dose to the surrounding tissues.

  16. QER- Comment of American Water

    Broader source: Energy.gov [DOE]

    Dear QER Team; Thank you for the opportunity to provide comments to the Quadrennial Energy Review Task Force to discuss the water and energy nexus, advances in water innovative technologies, and the impact of climate change on water issues. On behalf of American Water, I wish to submit the following White Papers which we have prepared on these critical issues: Innovations in Energy Use Sustainability and Resiliency Planning for Water Utilities One Water Water/Energy Correlation The Value of Water Challenges in the Water Industry: Climate Change Challenges in the Water Industry: Meeting Demand in the West Innovation Solutions Within the Water Industry: Desalination Innovation Solutions Within the Water Industry: Going Green Innovation Solutions Within the Water Industry: Water Reuse Bridging the Water Innovation Gap. Founded in 1886, American Water is the largest publicly traded U.S. water and wastewater utility company. With headquarters in Voorhees, NJ, the company employs approximately 6,600 dedicated professionals who provide drinking water, wastewater and other related services to an estimated 14 million people in more than 40 states. Please feel free to contact me if you have any questions or if there is any way American Water can be helpful to your mission. Respectfully Yours, Martin (See attached file: White Papers.pdf) Martin D. Kerckhoff Vice President and Divisional General Counsel Central Division American Water CONFIDENTIAL & PRIVILEGED COMMUNICATION This email and any attachments hereto constitute a legally confidential communication from the Legal Department of American Water. The information contained herein is subject to attorney-client privilege and is for the sole use of the intended original addressee. If you are not the intended original addressee, you are hereby notified that any reading, disclosure, copying, distribution, use, or taking of any action in reliance on the contents contained herein is strictly prohibited. If you have received this message in error, please immediately notify us at 314.966.2241 and delete this message from your system. WARNING: Although American Water has taken reasonable precautions to ensure that no viruses are present in this email, it is the responsibility of the recipient to ensure that it is virus free. No responsibility is accepted by American Water for any loss or damage arising in any way from the receipt and/or use of this email.

  17. SU-E-T-351: Verification of Monitor Unit Calculation for Lung...

    Office of Scientific and Technical Information (OSTI)

    States Language: English Subject: 60 APPLIED LIFE SCIENCES; COMPUTERIZED TOMOGRAPHY; LUNGS; MONTE CARLO METHOD; RADIATION DOSES; RADIATION MONITORS; RADIOTHERAPY; SPATIAL...

  18. SU-F-BRE-07: Experimental Validation of a Lung SBRT Technique...

    Office of Scientific and Technical Information (OSTI)

    of Publication: United States Language: English Subject: 60 APPLIED LIFE SCIENCES; LUNGS; PATIENTS; PHANTOMS; PLANNING; PLASTICS; RADIATION DOSE DISTRIBUTIONS; RADIATION...

  19. Pulmonary Artery Pseudoaneurysm Related to Radiofrequency Ablation of Lung Tumor

    SciTech Connect (OSTI)

    Sakurai, Jun, E-mail: sakurai@cc.okayama-u.ac.jp; Mimura, Hidefumi; Gobara, Hideo; Hiraki, Takao; Kanazawa, Susumu [Okayama University Medical School, Department of Radiology (Japan)

    2010-04-15

    We describe a case of pulmonary artery (PA) pseudoaneurysm related to radiofrequency ablation (RFA) of lung tumor. We performed RFA for a pulmonary epithelioid hemangioendothelioma directly adjacent to a branch of the PA. Seventeen days later, the patient complained of hemoptysis. A chest CT image revealed PA pseudoaneurysm. Transcatheter coil embolization was performed 59 days after RFA. Although PA pseudoaneurysm is rare, with an incidence of 0.2% (1/538 sessions) at our institution, it should be recognized as a risk when treating lung tumors adjacent to a branch of the PA.

  20. Perfusion lung scan: an aid in detection of lymphangitic carcinomatosis

    SciTech Connect (OSTI)

    Bates, S.E.; Tranum, B.L.

    1982-07-15

    Lymphangitic carcinomatosis is usually a late manifestation of metastatic disease. The patient usually presents with cough or dyspnea, and the chest radiograph is often nondiagnostic. Two patients are presented who developed symptoms while on adjuvant chemotherapy. Both had abnormal perfusion lung scans. One had matching ventilation defects; the other a normal ventilation study. Biopsy revealed metastatic carcinoma; in one case tumor was seen in both the pulmonary lymphatics and arterioles; in the other, tumor was identified but the site could not be specified. The radionuclide lung scan is a technique which can speed diagnosis and institution of therapy in lymphangitic carcinomatosis.

  1. Relating Airway Diameter Distributions to Regular Branching Asymmetry in the Lung Arnab Majumdar,1,2

    E-Print Network [OSTI]

    Buldyrev, Sergey

    Relating Airway Diameter Distributions to Regular Branching Asymmetry in the Lung Arnab Majumdar,1 as a function of generation N in asymmetric airway trees of mammalian lungs. We find that the airway]. Most models of the lung airway tree either do not address the observed diameter heterogeneity or simply

  2. Scaling behavior in crackle sound during lung inflation Adriano M. Alencar,1,2

    E-Print Network [OSTI]

    Stanley, H. Eugene

    Scaling behavior in crackle sound during lung inflation Adriano M. Alencar,1,2 Zolta´n Hantos,3 received 14 July 1999 During slow inflation of lung lobes, we measure a sequence of short explosive are a consequence of structural heterogeneity in the lung, ii the intermittent behavior is due to the avalanchelike

  3. Fluid transport in branched structures with temporary closures: A model for quasistatic lung inflation

    E-Print Network [OSTI]

    Buldyrev, Sergey

    Fluid transport in branched structures with temporary closures: A model for quasistatic lung a model system relevant to the inflation of a mammalian lung, an asymmetric bifurcating structure description of the underlying branching structure of the lung, by analyzing experimental pressure-volume data

  4. Mechanical interactions between collagen and proteoglycans: implications for the stability of lung tissue

    E-Print Network [OSTI]

    Alencar, Adriano Mesquita

    Mechanical interactions between collagen and proteoglycans: implications for the stability of lung- tions for the stability of lung tissue. J Appl Physiol 98: 672­679, 2005. First published September 24- ticity of the connective tissue including lung parenchyma. The gly- cosaminoglycans on the proteoglycans

  5. Lung and alveolar wall elastic and hysteretic behavior in rats: effects of in vivo elastase treatment

    E-Print Network [OSTI]

    Alencar, Adriano Mesquita

    Lung and alveolar wall elastic and hysteretic behavior in rats: effects of in vivo elastase P. Ingenito, and Be´la Suki. Lung and alveolar wall elastic and hysteretic behavior in rats: effects behavior of the alveolar walls and the macroscopic mechanical properties of the whole lung in an in vivo

  6. -Actin: disposition, quantities, and estimated effects on lung recoil and compliance

    E-Print Network [OSTI]

    -Actin: disposition, quantities, and estimated effects on lung recoil and compliance E. H. OLDMIXON, Jr. -Actin: disposition, quantities, and estimated effects on lung recoil and compliance. J Appl by measuring dispo- sition and quantities of -smooth muscle actin in rat and guinea pig lungs and modeling its

  7. Physica A 357 (2005) 1826 Crackles and instabilities during lung inflation

    E-Print Network [OSTI]

    Stanley, H. Eugene

    2005-01-01

    Physica A 357 (2005) 18­26 Crackles and instabilities during lung inflation Adriano M. Alencara, called the ``active surface''. We define the active surface of the lung as the set of airway segments and open regions in a collapsed lung. To study the active surface and the time interval between consecutive

  8. Reduced xenon diffusion for quantitative lung studythe role of SF6

    E-Print Network [OSTI]

    Walsworth, Ronald L.

    Reduced xenon diffusion for quantitative lung studyÐthe role of SF6 Ross W. Mair,1 * Dominik in most NMR experiments. In restricted environments, such as the lung, this rapid gas diffusion can lead the development of lung ventilation MRI using laser-polarized noble gases (129 Xe and 3 He),1,2 attention has been

  9. Monte Carlo simulation of liquid bridge rupture: Application to lung physiology Adriano M. Alencar,1

    E-Print Network [OSTI]

    Alencar, Adriano Mesquita

    Monte Carlo simulation of liquid bridge rupture: Application to lung physiology Adriano M. Alencar of certain lung diseases, the surface properties and the amount of fluids coating the airways changes of similar bridges that exist in diseased lungs. DOI: 10.1103/PhysRevE.74.026311 PACS number s : 47.90 a, 04

  10. Line Narrowing of Fiber Coupled Laser Diode Array He Lung MRI

    E-Print Network [OSTI]

    Walsworth, Ronald L.

    Line Narrowing of Fiber Coupled Laser Diode Array and 3 He Lung MRI by Jermane E. Massey B Coupled Laser Diode Array and 3 He Lung MRI by Jermane E. Massey Submitted to the Department of PhysicsW of injected power. A novel MRI coil and polarization system were developed for hyper-polarized 3 He lung

  11. Posture-dependent Human 3He Lung Imaging in an Open-access MRI System

    E-Print Network [OSTI]

    Walsworth, Ronald L.

    Posture-dependent Human 3He Lung Imaging in an Open-access MRI System: Initial Results1 Leo L. Tsai. Walsworth, PhD Rationale and Objectives. The human lung and its functions are extremely sensitive in determining lung function and heterogeneity of perfusion and ventilation. However, study of these effects

  12. Shallow and Deep Lunge Feeding of Humpback Whales in Fjords of the West Antarctic Peninsula

    E-Print Network [OSTI]

    Ware, Colin

    1 Shallow and Deep Lunge Feeding of Humpback Whales in Fjords of the West Antarctic Peninsula Colin lunges during which they engulf large volumes of water equal to as much as 70% of their body mass. To understand the kinematics of humpback lunge feeding, we attached high-resolution digital recording tags

  13. Magnetomotive optical coherence elastography for relating lung structure and function in Cystic Fibrosis

    E-Print Network [OSTI]

    Oldenburg, Amy

    Magnetomotive optical coherence elastography for relating lung structure and function in Cystic and normal lung tissues using OCT and correlative study with histology is also examined. We also demonstrate changes in CF lung structure and function and the novel method of longitudinal in vitro ECM assessment

  14. Mathematical Modeling of the First Inflation of Degassed Lungs BELA SUKI,* JOSE S. ANDRADE, JR.,

    E-Print Network [OSTI]

    Stanley, H. Eugene

    Mathematical Modeling of the First Inflation of Degassed Lungs BE´LA SUKI,* JOSE´ S. ANDRADE, JR--The pressure­volume (P­V) relationship of de- gassed lungs during the first inflation is different from and degassed rabbit lungs. By fitting these data, we found that n 17 5, Plow 23 4 cmH2O

  15. Acoustic evidence of airway opening during recruitment in excised dog lungs Z. Hantos,1

    E-Print Network [OSTI]

    Alencar, Adriano Mesquita

    Acoustic evidence of airway opening during recruitment in excised dog lungs Z. Hantos,1 J. Tolnai,1. Majumdar, and B. Suki. Acoustic evidence of airway opening during recruitment in excised dog lungs. J Appl-volume curve in the normal lung are primarily determined by airway reopen- ings via avalanches rather than

  16. Massive Hemoptysis from Pulmonary Artery Pseudoaneurysm Caused by Lung Radiofrequency Ablation: Successful Treatment by Coil Embolization

    SciTech Connect (OSTI)

    Yamakado, Koichiro, E-mail: yama@clin.medic.mie-u.ac.jp; Takaki, Haruyuki [Mie University School of Medicine, Department of Radiology (Japan); Takao, Motoshi [Mie University School of Medicine, Department of Thoracic Surgery (Japan); Murashima, Shuichi; Kodama, Hiroshi; Kashima, Masataka; Nakatsuka, Atsuhiro; Uraki, Junji [Mie University School of Medicine, Department of Radiology (Japan); Shimpo, Hideto [Mie University School of Medicine, Department of Thoracic Surgery (Japan); Takeda, Kan [Mie University School of Medicine, Department of Radiology (Japan)

    2010-04-15

    A 75-year-old man received lung radiofrequency (RF) ablation to treat lung metastases from hepatocellular carcinoma. Massive hemoptysis occurred 1 week after lung RF ablation. Emergent contrast-enhanced CT and pulmonary arteriography revealed a pulmonary artery pseudoaneurysm, which was embolized with coils. The postembolization course was uneventful. Hemoptysis did not recur for 5 months.

  17. Diagnosis and prognosis of neuroendocrine tumours of the lung by means of high

    E-Print Network [OSTI]

    Rodenacker, Karsten

    109 Diagnosis and prognosis of neuroendocrine tumours of the lung by means of high resolution image tumours (NET) of the lung are divided in subtypes with different malignant potential. The first and worse prognosis indepen- dent of staging and tumour type. Keywords: Neuroendocrine lung tumours

  18. Asthma is a chronic inflammatory disease of the lungs that is increasingly observed in developed countries

    E-Print Network [OSTI]

    Cai, Long

    Asthma is a chronic inflammatory disease of the lungs that is increasingly observed in developed in the lungs. However, characteristic to both forms of the disease is the airway- wall accumulation of T helper are expressed either by skin8 or lung epithelial cells and can influence the way in which epithelial cells

  19. Circulation . Author manuscript Activation of lung p53 by Nutlin-3a prevents and reverses experimental

    E-Print Network [OSTI]

    Boyer, Edmond

    Circulation . Author manuscript Page /1 14 Activation of lung p53 by Nutlin-3a prevents PA-SMCs; lung p53, p21, and MDM2 protein levels; and p21, Bax, PUMA, BTG2, and MDM2 mRNA levels or reversal by Nutlin-3a required lung p53 stabilization and increased p21 expression, as indicated

  20. Volume Estimation and Surgery Planning from Lung CT Images ANA ELISA FERREIRA SCHMIDT

    E-Print Network [OSTI]

    Volume Estimation and Surgery Planning from Lung CT Images ANA ELISA FERREIRA SCHMIDT 1 , PAULO to assist the planning of lung reduction surgeries, a technique that has been proposed for the treatment of certain illnesses. Doctors need to decide which portions of the lungs to remove to achieve a certain

  1. RESEARCH Open Access Accuracy and precision of end-expiratory lung-

    E-Print Network [OSTI]

    RESEARCH Open Access Accuracy and precision of end-expiratory lung- volume measurements , Gilles Bernardin2 and Laurent Brochard1,9,10 Abstract Introduction: End-expiratory lung volume (EELV in lung volume above functional residual capacity measured with passive spirometry (PEEP

  2. Impact of axial diffusion on nitric oxide exchange in the lungs

    E-Print Network [OSTI]

    George, Steven C.

    Impact of axial diffusion on nitric oxide exchange in the lungs HYE-WON SHIN1 AND STEVEN C. GEORGE1, Hye-Won, and Steven C. George. Impact of axial diffusion on nitric oxide exchange in the lungs. J Appl of the lungs, but neglects axial diffusion. We incorporated axial diffusion into a one-dimensional trumpet

  3. Slit and robo: expression patterns in lung development Mark A. Anselmoa

    E-Print Network [OSTI]

    Wu, Jane Y.

    Slit and robo: expression patterns in lung development Mark A. Anselmoa , Sussie Dalvina , Parthak and elongation. Indirect evidence implicates Slit and Robo in lung development. We now demonstrate that Slit-2 and Slit-3 are developmentally regulated in embryonic murine lung. Immunohistochemistry demonstrates Slit-2

  4. CLARET: A Fast Deformable Registration Method Applied to Lung Radiation Therapy

    E-Print Network [OSTI]

    CLARET: A Fast Deformable Registration Method Applied to Lung Radiation Therapy Chen-Rui Chou1 and accurate image-guided radiother- apy in lung with low-dose imaging. CLARET contains three components: shape. At treatment time, CLARET computes a patient's lung deformations by iteratively apply- ing the learned

  5. A Framework for Unsupervised Segmentation of Lung Tissues from Low Dose Computed

    E-Print Network [OSTI]

    Kim, Tae-Kyun

    A Framework for Unsupervised Segmentation of Lung Tissues from Low Dose Computed Tomography Images of lung tis- sues from Low Dose Computed Tomography (LDCT) are proposed. In this paper we describe LDCT images and desired maps of regions (lung and the other chest tissues) by a joint Markov-Gibbs random

  6. The porcine lung as a potential model for cystic fibrosis Christopher S. Rogers,1

    E-Print Network [OSTI]

    Engelhardt, John F.

    Review The porcine lung as a potential model for cystic fibrosis Christopher S. Rogers,1 William M, Prather RS, Sabater JR, Stoltz DA, Zabner J, Welsh MJ. The porcine lung as a potential model for cystic fibrosis. Am J Physiol Lung Cell Mol Physiol 295: L240­L263, 2008. First published May 16, 2008; doi:10

  7. A Distributed Biomarker Atlas for Lung Research aiding the Discovery and Early Detection of Cancer Biomarkers

    E-Print Network [OSTI]

    Mattmann, Chris

    A Distributed Biomarker Atlas for Lung Research aiding the Discovery and Early Detection of Cancer Atlas software system that allows a researcher to correlate lung cancer patients with similar characteristics around regions of the lung in which their sample specimens including multiple types

  8. STATISTICAL MODELING OF THE LUNG NODULES IN LOW DOSE COMPUTED TOMOGRAPHY SCANS OF THE CHEST

    E-Print Network [OSTI]

    Louisville, University of

    STATISTICAL MODELING OF THE LUNG NODULES IN LOW DOSE COMPUTED TOMOGRAPHY SCANS OF THE CHEST Amal in automatic detection of the lung nodules and is compared with respect to parametric nodule models in terms appearing in low dose CT (LDCT) scans of the human chest. Four types of common lung nodules are analyzed

  9. Modeling Respiratory Lung Motion a Biophysical Approach using Finite Element Methods

    E-Print Network [OSTI]

    Lübeck, Universität zu

    Modeling Respiratory Lung Motion ­ a Biophysical Approach using Finite Element Methods Rene Wernera motion gains in importance. In this paper a biophysical approach for modeling lung motion is described. Main aspects of the process of lung ventilation are identified and outlined as the starting point

  10. Integrated proteomic and transcriptomic profiling of mouse lung development and Nmyc target genes

    E-Print Network [OSTI]

    Frey, Brendan J.

    Integrated proteomic and transcriptomic profiling of mouse lung development and Nmyc target genes provided information regarding the dynamics of gene expression during development of the mouse lung a global survey of protein expression during mouse lung organogenesis from embryonic day E13.5 until

  11. Modeling Alveolar Volume Changes During Periodic Breathing in Heterogeneously Ventilated Lungs

    E-Print Network [OSTI]

    Jeavons, Peter

    Modeling Alveolar Volume Changes During Periodic Breathing in Heterogeneously Ventilated Lungs SARA-uniform breathing pattern for a lung with an inhomogeneous gas distribution, such as that observed in some subjects of irregular breathing caused by small, poorly ventilated regions of the lung. Presented here is an extension

  12. Theoretical Gas Phase Mass Transfer Coefficients for Endogenous Gases in the Lungs

    E-Print Network [OSTI]

    George, Steven C.

    Theoretical Gas Phase Mass Transfer Coefficients for Endogenous Gases in the Lungs PETER CONDORELLI, is produced within the tissue of the airways of the lungs.16 As an intercellular messenger, NO is involved is available regarding the basic gas exchange dynamics of NO in the lungs. Ingested ethanol EtOH is transported

  13. Morphology of the Small-Animal Lung Using Magnetic Resonance Microscopy

    E-Print Network [OSTI]

    Morphology of the Small-Animal Lung Using Magnetic Resonance Microscopy Laurence W. Hedlund and G motion control and animal support, the lungs of the live, small animal can be imaged. Although in vivo He, it is possible to image the tissue and gas compartments of the lung. This capability

  14. Visualization of Density Variation in Lung Aristofanes C. Silva a,, Paulo Cezar P. Carvalho b

    E-Print Network [OSTI]

    Visualization of Density Variation in Lung Nodules Arist´ofanes C. Silva a,, Paulo Cezar P de Janeiro, RJ, Brazil Abstract We propose a method for visualize lung nodule, in order to emphasize submitted to Medical Image Analysis 27 May 2002 #12;1 Introduction Lung cancer is known to be the form

  15. Effet of Combined Nitrogen Dioxide and Carbon Nanoparticle Exposure on Lung Function During

    E-Print Network [OSTI]

    Boyer, Edmond

    Effet of Combined Nitrogen Dioxide and Carbon Nanoparticle Exposure on Lung Function During and Respiratory Medicine, Paediatric Lung Function Laboratory, Amiens University Hospital, Amiens, France, 3 and challenges in Borwn-Norway (BN) rat, in order to assess their interactions on lung function and airway

  16. Optimal Surface Marker Locations for Tumor Motion Estimation in Lung Cancer Radiotherapy

    E-Print Network [OSTI]

    Soatto, Stefano

    Optimal Surface Marker Locations for Tumor Motion Estimation in Lung Cancer Radiotherapy Bin Dong is a widely used approach in lung cancer radiotherapy. The purpose of this work is to propose an algorithm been tested on realistic clinical data of four lung cancer patients. Thoracic 4DCT scans with 10 phases

  17. Branching morphogenesis of the lung: new molecular insights into an old

    E-Print Network [OSTI]

    Chuang, Pao-Tien

    Branching morphogenesis of the lung: new molecular insights into an old problem Pao-Tien Chuang1 It has been known for decades that branching morpho- genesis of the lung is mediated through reciprocal between major signaling path- ways during branching morphogenesis of the lung in mice. It has been known

  18. The fractality of lung sounds: A comparison of three waveform fractal dimension algorithms

    E-Print Network [OSTI]

    Moussavi, Zahra M. K.

    The fractality of lung sounds: A comparison of three waveform fractal dimension algorithms January of flow-specific lung sounds (LS) have been compared to examine the fractal nature of these signals. LS between LS in health and disease. Ó 2005 Elsevier Ltd. All rights reserved. 1. Introduction Lung sounds

  19. Assessment of morphometry of pulmonary acini in mouse lungs by nondestructive imaging using

    E-Print Network [OSTI]

    Wang, Ge

    Assessment of morphometry of pulmonary acini in mouse lungs by nondestructive imaging using a more complete understanding of the relationship of lung structure and function. We combined a special to separate individual acini in the mouse lung. Interior scans of the parenchyma at a resolution of 2 µm

  20. Toward Robotic Needle Steering in Lung Biopsy: A Tendon-Actuated Approach

    E-Print Network [OSTI]

    Toward Robotic Needle Steering in Lung Biopsy: A Tendon-Actuated Approach Louis B. Kratchman is advantageous for transthoracic lung biopsies, which are typically performed with rigid, straight biopsy needles for transthoracic lung biopsy. The system is designed to insert and steer the needle under Computed Tomography (CT

  1. A novel strategy for surface modification of superparamagnetic iron oxide nanoparticles for lung cancer imaging

    E-Print Network [OSTI]

    Gao, Jinming

    A novel strategy for surface modification of superparamagnetic iron oxide nanoparticles for lung-step procedure for the surface functionalization of SPIO nanoparticles with a lung cancer-targeting peptide and demonstrate high T2 relaxivity. The nanoprobes are specific in targeting avb6­expressing lung cancer cells

  2. Experimental Evaluation of a Model for Oxygen Exchange in a Pulsating Intravascular Artificial Lung

    E-Print Network [OSTI]

    Federspiel, William J.

    Experimental Evaluation of a Model for Oxygen Exchange in a Pulsating Intravascular Artificial Lung an intravascular hollow fiber artificial lung that uses a pulsating balloon located within the fiber bundle in pulsating intravascular artificial lungs. In this study we evaluate the O2 exchange model with gas exchange

  3. Using Continuum Robots to Enable Transoral Access to the Peripheral Lung for Minimally Invasive Biopsy

    E-Print Network [OSTI]

    Using Continuum Robots to Enable Transoral Access to the Peripheral Lung for Minimally Invasive Biopsy Arthur W. Mahoney, Philip J. Swaney, and Robert J. Webster III Lung cancer kills more people than reach regions adjacent to bronchii. Enables access to the peripheral lung for biopsy without puncturing

  4. Influence of Pulmonary Surfactant Protein B on Model Lung Surfactant Monolayers

    E-Print Network [OSTI]

    Zasadzinski, Joseph A.

    Influence of Pulmonary Surfactant Protein B on Model Lung Surfactant Monolayers Frank Bringezu reveal that human lung surfactant protein SP-B1-78 and the dimer of the amino terminus dSP-B1-25 modify be essential for proper peptide function. Introduction Lung surfactant is a complex mixture of lipids

  5. Collagen-related gene and protein expression changes in the lung in response to chronic hypoxia

    E-Print Network [OSTI]

    Chesler, Naomi C.

    Collagen-related gene and protein expression changes in the lung in response to chronic hypoxia changes in gene and protein expression in the lungs of mice exposed to hypoxia for 0, 3, 6, 10 and 15 days was increased in whole lungs as early as 6 days of hypoxia and increased monotonically with longer exposures

  6. Comment on ``Ultrasound-induced lung hemorrhage is not caused by inertial cavitation''

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Comment on ``Ultrasound-induced lung hemorrhage is not caused by inertial cavitation'' [J. Acoust­1297 2000 that ultrasound-induced lung hemorrhage is not caused by inertial cavitation. An argument is provided that illustrates how cavitation inception conditions in the lungs of animals are not altered

  7. AN INTEGRATED LUNG-ON-A-CHIP MICROFLUIDIC PLATFORM WITH REAL-TIME BIOCHEMICAL SENSING

    E-Print Network [OSTI]

    Kassegne, Samuel Kinde

    AN INTEGRATED LUNG-ON-A-CHIP MICROFLUIDIC PLATFORM WITH REAL-TIME BIOCHEMICAL SENSING, without finding it. ­ Lucius Annaeus Seneca #12;v ABSTRACT OF THE THESIS An Integrated Lung for detection. In this research, we replicate the Lung-on- a-Chip platform with a cystic fibrosis cell line

  8. THRESHOLD ESTIMATES OF ULTRASOUND-INDUCED LUNG HEMORRHAGE IN ADULT RATS: ROLE OF PULSE DURATION

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    THRESHOLD ESTIMATES OF ULTRASOUND-INDUCED LUNG HEMORRHAGE IN ADULT RATS: ROLE OF PULSE DURATION W-induced lung hemorrhage has been estimated as a function of pulse duration (PD) in adult rats. A total of 220, there were five in situ (at the lung surface) peak rarefactional pressures. For PDs of 1.3, 4.4, 8.2, and 11

  9. Effect of pulse polarity and energy on ultrasound-induced lung hemorrhage in adult rats

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Effect of pulse polarity and energy on ultrasound-induced lung hemorrhage in adult rats Leon A the role of inertial cavitation in ultrasound-induced lung hemorrhage by examining the effect of pulse polarity at a common in situ at the lung surface peak rarefactional pressure pr(in situ) and at a common

  10. Attenuation and speed of ultrasoundin lung BioacousticResearchLaboratory,Universityof Illinois,Urbana,Illinois61801

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Attenuation and speed of ultrasoundin lung F. Dunn Bioacoustic in freshly excised dog lung at 1 MHz was un- usuallyhigh,viz., morethananorderofmagnitude greater than air excised lung was ligated at the bronchial tube to retain such residual air that the density of the speci

  11. Lesion Resolution Following Exposure of Rat Lung to Pulsed Ultrasound James F. Zachary,1

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Lesion Resolution Following Exposure of Rat Lung to Pulsed Ultrasound James F. Zachary,1 Leon A ultrasound-induced lung hemorrhage in mice, rats, rabbits, monkeys, and pigs. This study characterized the temporal reparative (healing) responses in lung fol- lowing the induction of lesions by pulsed ultrasound

  12. Reduced Order Constrained Optimization (ROCO):1 Clinical Application to Lung IMRT2

    E-Print Network [OSTI]

    Reduced Order Constrained Optimization (ROCO):1 Clinical Application to Lung IMRT2 Hans Stabenau,1 quickly and automatically for advanced lung cancer patients. Our new ROCO imple- mentation works constrained optimization computationally efficient. Results: We apply ROCO to 12 stage III non-small-cell lung

  13. Feasibility of Locating Tumours in Lung via Kinesthetic Feedback Greig L. McCreery

    E-Print Network [OSTI]

    Naish, Michael D.

    Feasibility of Locating Tumours in Lung via Kinesthetic Feedback Greig L. McCreery Ana Luisa Trejos Michael D. Naish Rajni V. Patel Richard A. Malthaner Abstract Background Localizing lung tumours during-operative imaging cannot map directly to the intra-operative lung. This study analyzes the force sensing performance

  14. Medical Physics Letter Digital tomosynthesis of the chest for lung nodule detection: Interim

    E-Print Network [OSTI]

    Medical Physics Letter Digital tomosynthesis of the chest for lung nodule detection: Interim tomosynthesis for improving detectability of small lung nodules. Twenty-one patients under- going computed tomography CT to follow up lung nodules were consented and enrolled to receive an additional digital PA chest

  15. Tendons, Concentric Tubes, and a Bevel Tip: Three Steerable Robots in One Transoral Lung Access System

    E-Print Network [OSTI]

    Tendons, Concentric Tubes, and a Bevel Tip: Three Steerable Robots in One Transoral Lung Access, and Robert J. Webster III1, Senior Member, IEEE Abstract-- Lung cancer is the most deadly form of cancer between-the-ribs needle insertion because it is less invasive and reduces risk of lung collapse. Yet many

  16. Feasibility Study of Dual Energy Radiographic Imaging for Target Localization in Radiotherapy for Lung Tumors

    E-Print Network [OSTI]

    for Lung Tumors Jie Huo1 , Xianfeng Zhu1 , Yang Dong2 , Zhiyong Yuan2 , Ping Wang2 *, Xuemin Wang1 , Gang. 10 lung cancer patients who underwent radiotherapy each with gold markers implanted in the tumor were Imaging for Target Localization in Radiotherapy for Lung Tumors. PLoS ONE 9(9): e108823. doi:10

  17. A Comparative In Vitro Hemolysis Study of a Pulsating Intravenous Artificial Lung

    E-Print Network [OSTI]

    Federspiel, William J.

    A Comparative In Vitro Hemolysis Study of a Pulsating Intravenous Artificial Lung LAURA W. LUND oxygenation and carbon dioxide removal lead to further damage of the ailing lungs.1 An estimated 150) as a method for providing temporary respiratory support and allowing the lungs of ARDS patients to heal.4

  18. An Adaptive, Knowledge-Driven Medical Image Search Engine for Interactive Diffuse Parenchymal Lung Disease

    E-Print Network [OSTI]

    Chandy, John A.

    An Adaptive, Knowledge-Driven Medical Image Search Engine for Interactive Diffuse Parenchymal Lung Abstract Characterization and quantification of the severity of diffuse parenchymal lung diseases (DPLD have been obtained on a small test set. Keywords: CT; texture analysis; interstitial lung disease

  19. Ultrasound-induced lung hemorrhage is not caused by inertial cavitation

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Ultrasound-induced lung hemorrhage is not caused by inertial cavitation William D. O'Brien, Jr, the pathogenesis of lung hemorrhage due to exposure to clinical diagnostic levels of ultrasound has been attributed that directly contradict the hypothesis that ultrasound-induced lung hemorrhage is caused by inertial cavitation

  20. Motion Planning for a Three-Stage Multilumen Transoral Lung Access System

    E-Print Network [OSTI]

    Alterovitz, Ron

    Motion Planning for a Three-Stage Multilumen Transoral Lung Access System Alan Kuntz, Luis G. Torres, Richard H. Feins, Robert J. Webster III, and Ron Alterovitz Abstract-- Lung cancer is the leading required for a definitive diagnosis, but current low-risk clinical options for lung biopsy cannot access

  1. LETTER doi:10.1038/nature13173 Reconstructing lineage hierarchies of the distal lung

    E-Print Network [OSTI]

    Quake, Stephen R.

    LETTER doi:10.1038/nature13173 Reconstructing lineage hierarchies of the distal lung epithelium The mammalian lung is a highly branched network in which the distal regions of the bronchial tree transform-mapping, the mechanisms that control the progression of lung progenitors along distinct lineages into mature alveolar cell

  2. Video Article Characterization of the Isolated, Ventilated, and Instrumented Mouse Lung

    E-Print Network [OSTI]

    Chesler, Naomi C.

    Video Article Characterization of the Isolated, Ventilated, and Instrumented Mouse Lung Perfused://www.jove.com/details.php?id=2690 DOI: 10.3791/2690 Keywords: Medicine, Issue 50, ex-vivo, mouse, lung, pulmonary vascular impedance of the Isolated, Ventilated, and Instrumented Mouse Lung Perfused with Pulsatile Flow. J. Vis. Exp. (50), e2690

  3. Silicon Photonic Crystal Microcavity Biosensors for Label Free Highly Sensitive and Specific Lung Cancer Detection

    E-Print Network [OSTI]

    Chen, Ray

    Silicon Photonic Crystal Microcavity Biosensors for Label Free Highly Sensitive and Specific Lung detect lung cancer cell lysates with high sensitivity down to 2 cells per microliter with silicon based detection of control experiment to verify specificity again. Primary lung cancer develops from epithelial

  4. Robust Segmentation of Challenging Lungs in CT using Multi-Stage Learning

    E-Print Network [OSTI]

    Robust Segmentation of Challenging Lungs in CT using Multi-Stage Learning and Level Set.Kevin Zhou1 Abstract Automatic segmentation of lung tissue in thoracic CT scans is useful for diagnosis and treatment planning of pulmonary diseases. Unlike healthy lung tissue that is easily identifiable in CT scans

  5. Relating maximum airway dilation and subsequent reconstriction to reactivity in human lungs

    E-Print Network [OSTI]

    Lutchen, Kenneth

    Relating maximum airway dilation and subsequent reconstriction to reactivity in human lungs Lauren in human lungs. J Appl Physiol 96: 1808­1814, 2004. First published February 6, 2004; 10.1152/japplphysiol reactivity in healthy lungs by prohibiting DI for an extended period. The present study had two goals. First

  6. Technical Reports Ultra-low Dose Lung CT Perfusion Regularized by

    E-Print Network [OSTI]

    Wang, Ge

    Technical Reports Ultra-low Dose Lung CT Perfusion Regularized by a Previous Scan1 Hengyong Yu, Ph­regularized reconstruction (PSRR) method was proposed to reduce radiation dose and applied to lung perfusion studies. Normal and ultra-low-dose lung computed tomographic perfusion studies were compared in terms of the estimation

  7. Tissue heterogeneity in the mouse lung: effects of elastase treatment Satoru Ito,1

    E-Print Network [OSTI]

    Lutchen, Kenneth

    Tissue heterogeneity in the mouse lung: effects of elastase treatment Satoru Ito,1 Edward P heterogeneity in the mouse lung: effects of elastase treatment. J Appl Physiol 97: 204­212, 2004. First to characterize heterogeneity of tissue elasticity of the lung. The model includes a parallel set of pathways

  8. Multi-stage Learning for Robust Lung Segmentation in Challenging CT Volumes

    E-Print Network [OSTI]

    Multi-stage Learning for Robust Lung Segmentation in Challenging CT Volumes Michal Sofka1 , Jens Imaging, Siemens Healthcare, Oxford, UK Abstract. Simple algorithms for segmenting healthy lung parenchyma an ini- tialization of a statistical shape model of the lungs. The initialization first detects

  9. Location registration and recognition (LRR) for serial analysis of nodules in lung CT scans

    E-Print Network [OSTI]

    Location registration and recognition (LRR) for serial analysis of nodules in lung CT scans Michal t In the clinical workflow for lung cancer management, the comparison of nodules between CT scans from subsequent in investigating the condition of the lung. The algorithm uses a combination of feature extraction, indexing

  10. JAP-00590-2004 Mechanics, nonlinearity, and failure strength of lung tissue in a mouse

    E-Print Network [OSTI]

    Lutchen, Kenneth

    JAP-00590-2004 Mechanics, nonlinearity, and failure strength of lung tissue in a mouse model% higher in the PPE-treated group (P lung hydroxyproline content, which represents remodeling may play a significant role in all aspects of lung functional changes leading to progressive

  11. Environmental Tobacco Smoke Effects on the Primary Lipids of Lung Surfactant

    E-Print Network [OSTI]

    Zasadzinski, Joseph A.

    Environmental Tobacco Smoke Effects on the Primary Lipids of Lung Surfactant Frank Bringezu,, Kent. In Final Form: December 2, 2002 The effects of environmental tobacco smoke (ETS) on lung surfactant are difficult to determine from analysis of human and animal lung lavage due to large variations in surfactant

  12. Relation Between Structure, Function, and Imaging in a Three-Dimensional Model of the Lung

    E-Print Network [OSTI]

    Lutchen, Kenneth

    Relation Between Structure, Function, and Imaging in a Three-Dimensional Model of the Lung NORA T morphometric mod- els to predict function relations in the lung. These models, however, are not anatomically explicit. We have advanced a three-dimensional airway tree model to relate dynamic lung function

  13. Response to ``Comment on `Ultrasound-induced lung hemorrhage is not caused by inertial cavitation'''

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Response to ``Comment on `Ultrasound-induced lung hemorrhage is not caused by inertial cavitation cavitation nuclei in lung versus other tissues such that overpressure does not affect the inertial cavitation threshold in lung, then there would be an impact on the con- clusion in our publication.2 To examine

  14. Antinuclear Antibodies as Potential Markers of Lung Cancer1 Felix Fernandez-Madrid,2

    E-Print Network [OSTI]

    VandeVord, Pamela

    Antinuclear Antibodies as Potential Markers of Lung Cancer1 Fe´lix Ferna´ndez-Madrid,2 Pamela J of ANAs in lung cancer. We have previously reported that autoantibodies to collagen antigens resembling those found in the connective tissue diseases are consistently detected in the sera from lung cancer

  15. Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth (Review)

    E-Print Network [OSTI]

    Rau, Don C.

    Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth://www.thecochranelibrary.com Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth (Review.09. Comparison 01 Corticosteroids versus placebo or no treatment, Outcome 09 Chronic lung disease . 83 Analysis

  16. Lung Sound Recognition Using Model-Theory Based Feature Selection and Fusion

    E-Print Network [OSTI]

    Kokar, Mieczyslaw M.

    Lung Sound Recognition Using Model-Theory Based Feature Selection and Fusion Zbigniew Korona recognition methodology to the recognition of lung sounds. Two main features of this method- ology are features using an entropy-based criterion. To evaluate the methodology we used both normal lung sounds

  17. Multi-level Ground Glass Nodule Detection and Segmentation in CT Lung Images

    E-Print Network [OSTI]

    Corso, Jason J.

    Multi-level Ground Glass Nodule Detection and Segmentation in CT Lung Images Yimo Tao1,2 , Le Lu1. Early detection of Ground Glass Nodule (GGN) in lung Computed Tomography (CT) images is important for lung cancer prog- nosis. Due to its indistinct boundaries, manual detection and segmenta- tion of GGN

  18. MONITORING LUNG DISEASE USING ELECTRONIC STETHOSCOPE ARRAYS Kyle Mulligan, Andy Adler, and Rafik Goubran

    E-Print Network [OSTI]

    Adler, Andy

    MONITORING LUNG DISEASE USING ELECTRONIC STETHOSCOPE ARRAYS Kyle Mulligan, Andy Adler, and Rafik evidence has shown that lung protective ventilation strategies lead to dramatic improvements in patient health by reducing ventilator induced lung injury (VILI) 1 . To protect against VILI, many novel modes

  19. Ultra-Fast Absorption of Amorphous Pure Drug Aerosols Via Deep Lung Inhalation

    E-Print Network [OSTI]

    Rabinowitz, Joshua D.

    Ultra-Fast Absorption of Amorphous Pure Drug Aerosols Via Deep Lung Inhalation JOSHUA D. RABINOWITZ. A promising means of accelerating drug action is through rapid systemic drug administration via deep lung inhalation. The speed of pulmonary drug absorption depends on the site of aerosol deposition within the lung

  20. Lung sound localization using array of acoustic S.M. Akramus Salehin and Thushara D. Abhayapala

    E-Print Network [OSTI]

    Abhayapala, Thushara D.

    1 Lung sound localization using array of acoustic sensors S.M. Akramus Salehin and Thushara D University Abstract-- This paper presents a localization algorithm to detect lung sounds using an circular by computer simulations. I. INTRODUCTION Lung disorders or injury can result in changes in the spectral and

  1. Selenium and Lung Cancer: A Quantitative Analysis of Heterogeneity in the Current

    E-Print Network [OSTI]

    California at Berkeley, University of

    Selenium and Lung Cancer: A Quantitative Analysis of Heterogeneity in the Current Epidemiological on sele- nium and lung cancer and identify sources of heterogeneity among studies. When all studies were.30). Overall, these results suggest that selenium may have some protective effect against lung cancer

  2. Mechanism Design and Implementation for Lung Exchange Suiqian Luo and Pingzhong Tang

    E-Print Network [OSTI]

    Tang, Pingzhong

    Mechanism Design and Implementation for Lung Exchange Suiqian Luo and Pingzhong Tang Institute@tsinghua.edu.cn Abstract We explore the mechanism design problem for lung exchange and its implementation in practice. We prove that determining whether there exists a non- trivial solution of the lung exchange problem is NP

  3. Choice of reconstructed tissue properties affects interpretation of lung EIT images

    E-Print Network [OSTI]

    Adler, Andy

    Choice of reconstructed tissue properties affects interpretation of lung EIT images Bartlomiej patients. In lung EIT, the EIT inverse problem is commonly linearised and only changes in electrical properties of the lung and artefacts introduced by the linearisation. #12;Choice of reconstructed tissue

  4. Stroke Belt Initiative 1National Heart, Lung, and Blood Institute Stroke Belt Initiative

    E-Print Network [OSTI]

    Shen, Jun

    Stroke Belt Initiative 1National Heart, Lung, and Blood Institute Stroke Belt Initiative NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Project Accomplishments and Lessons Learned Overview Cerebrovascular to those living in other regions of the country. The National Heart, Lung, and Blood Institute (NHLBI

  5. Lung deflation and oxygen pulse in COPD: Results from the NETT randomized trial*

    E-Print Network [OSTI]

    Lung deflation and oxygen pulse in COPD: Results from the NETT randomized trial* Carolyn E. Come a July 2011 Available online 16 August 2011 KEYWORDS Cardiac function; Hyperinflation; Lung volume function. We examined whether lung deflation improves oxygen pulse, a surrogate marker of stroke volume

  6. Original Contribution Elevated Lung Cancer in Younger Adults and Low Concentrations of Arsenic

    E-Print Network [OSTI]

    California at Berkeley, University of

    Original Contribution Elevated Lung Cancer in Younger Adults and Low Concentrations of Arsenic-term effects of arsenic. We performed a case-control study of lung cancer from 2007 to 2010 in areas or more years ago resulted in odds ratios for lung cancer of 1.00, 1.43 (90% confidence interval: 0.82, 2

  7. MRI-Visible Micellar Nanomedicine for Targeted Drug Delivery to Lung Cancer Cells

    E-Print Network [OSTI]

    Gao, Jinming

    MRI-Visible Micellar Nanomedicine for Targeted Drug Delivery to Lung Cancer Cells Jagadeesh Setti micelle (MFM) system that is encoded with a lung cancer-targeting peptide (LCP), and encapsulated. The LCP-encoded MFM showed significantly increased Rv 6-dependent cell targeting in H2009 lung cancer

  8. Learning Methods for Lung Tumor Markerless Gating in Image-Guided Radiotherapy

    E-Print Network [OSTI]

    Dy, Jennifer G.

    Learning Methods for Lung Tumor Markerless Gating in Image-Guided Radiotherapy Ying Cui Dept. For gated lung cancer radiotherapy, it is difficult to generate ac- curate gating signals due to the large techniques, we apply them on five sequences of fluoroscopic images from five lung cancer patients against

  9. Identifying Mathematical Models of the Mechanically Ventilated Lung Using Equation Discovery

    E-Print Network [OSTI]

    Kersting, Kristian

    1 Identifying Mathematical Models of the Mechanically Ventilated Lung Using Equation Discovery in intensive care medicine by all means. Nevertheless, it can induce severe mechanical stress to the lung, which generally impairs the outcome of the therapy. To reduce the risk of a ventilator induced lung

  10. Circulation during intermittent lung ventilation in the ~artel" snake Thamnophis WARREN B URG(;RFS

    E-Print Network [OSTI]

    Burggren, Warren

    I .'11 Circulation during intermittent lung ventilation in the ~artel" snake Thamnophis WARREN B" Vi'lllW5 Received April 26, 1'177 RU\\lung "/-'r1t relationship, within the central arterial circulation ",'ere observed during intermittent. voluntary lung

  11. Data-driven classification of ventilated lung tissues using electrical impedance tomography

    E-Print Network [OSTI]

    Adler, Andy

    Data-driven classification of ventilated lung tissues using electrical impedance tomography Camille for identifying ventilated lung regions utilizing electrical impedance tomography (EIT) images rely on dividing of a data-driven classification method to identify ventilated lung ROI based on forming k clusters from

  12. INT J TUBERC LUNG DIS 15(8):9961004 2011 The Union

    E-Print Network [OSTI]

    Cohen, Ted

    INT J TUBERC LUNG DIS 15(8):996­1004 ©2011 The Union doi:10.5588/ijtld.11.0062 STATE OF THE ART University, Taipei, Taiwan; International Union Against Tuberculosis and Lung Disease, Paris, France series in the Journal. Int J Tuberc Lung Dis 2011; 15(1): 3. No 1: Lienhardt C, Cobelens F G J

  13. Arsenic methylation and lung and bladder cancer in a case-control study in northern Chile

    E-Print Network [OSTI]

    California at Berkeley, University of

    Arsenic methylation and lung and bladder cancer in a case-control study in northern Chile Dawit Accepted 20 November 2013 Available online 1 December 2013 Keywords: Arsenic Cancer Methylation Lung about its role in lung cancer, the most common cause of arsenic-related death, or about its impacts

  14. Lobe-based Estimating Ventilation and Perfusion from 3D CT scans of the Lungs

    E-Print Network [OSTI]

    Warren, Joe

    Lobe-based Estimating Ventilation and Perfusion from 3D CT scans of the Lungs Travis McPhail Joe Warren Rice University Thomas Guerrero, M.D. M.D. Anderson Cancer Center Introduction Lung cancer for lung cancer includes surgical removal or radiation therapy. 3D imaging technologies such CT, MRI

  15. Original Contribution Acute Myocardial Infarction Mortality in Comparison with Lung and Bladder

    E-Print Network [OSTI]

    California at Berkeley, University of

    Original Contribution Acute Myocardial Infarction Mortality in Comparison with Lung and Bladder, 2007; accepted for publication July 27, 2007. Arsenic in drinking water is known to be a cause of lung lung and bladder cancer, AMI mortality was the predominant cause of excess

  16. IL-8 Production in Human Lung Fibroblasts and Epithelial Cells Activated by the Pseudomonas Autoinducer

    E-Print Network [OSTI]

    Springer, Timothy A.

    IL-8 Production in Human Lung Fibroblasts and Epithelial Cells Activated by the Pseudomonas is caused, in part, by the produc- tion of the chemokine IL-8, which recruits neutrophils into the lung. These findings support the concept that the severe lung damage that accompanies P. aeruginosa infections

  17. FALSE POSITIVE REDUCTION IN LUNG GGO NODULE DETECTION WITH 3D VOLUME SHAPE DESCRIPTOR

    E-Print Network [OSTI]

    Wu, Ying

    FALSE POSITIVE REDUCTION IN LUNG GGO NODULE DETECTION WITH 3D VOLUME SHAPE DESCRIPTOR Ming Yang. Malvern, PA 19355 Evanston, IL 60208 ABSTRACT Lung nodule detection, especially ground glass opacity (GGO on a difficult mixture lung nodule dataset with average 81% detec- tion rate and 4.3 false positives per volume

  18. Research Article Increased Lung and Bladder Cancer Incidence in Adults after

    E-Print Network [OSTI]

    California at Berkeley, University of

    Research Article Increased Lung and Bladder Cancer Incidence in Adults after In Utero and Early resulted in increased mortality in adults from several outcomes, including lung and bladder cancer. Methods data. Subjects included 221 lung and 160 bladder cancer cases diagnosed in northern Chile from 2007

  19. A NOVEL FRAMEWORK FOR ACCURATE LUNG SEGMENTATION USING GRAPH CUTS Asem M. Ali1

    E-Print Network [OSTI]

    Louisville, University of

    A NOVEL FRAMEWORK FOR ACCURATE LUNG SEGMENTATION USING GRAPH CUTS Asem M. Ali1 Ayman S. El-Baz 2 Bioengineering Department, University of Louisville ABSTRACT The closeness of the gray levels between lung tissues and the chest tissues makes lung segmentation based only on image signals dif- ficult. This work

  20. Sox9 plays multiple roles in the lung epithelium during branching morphogenesis

    E-Print Network [OSTI]

    Sander, Maike

    Sox9 plays multiple roles in the lung epithelium during branching morphogenesis Briana E. Rockicha, Durham, NC, and approved October 2, 2013 (received for review June 21, 2013) Lung branching morphogenesis lung. Intricate regulation of signaling pathways, tran- scription factors, and epithelial

  1. KILLING OF TARGET CELLS DUE TO RADON PROGENY IN THE HUMAN LUNG

    E-Print Network [OSTI]

    Yu, Peter K.N.

    KILLING OF TARGET CELLS DUE TO RADON PROGENY IN THE HUMAN LUNG B. M. F. Lau1 , D. Nikezic1,2 and K to inhaled radon progeny in the human lung. The present work uses the microdosimetric approach and determines/alleviate this discrepancy, including those based on different lung morpho- metry models(4) , different ethnic groups(5

  2. Appeared in: IEEE Visualization 2003 Hybrid Segmentation and Exploration of the Human Lungs

    E-Print Network [OSTI]

    Bartz, Dirk

    Appeared in: IEEE Visualization 2003 Hybrid Segmentation and Exploration of the Human Lungs Dirk on a PC with a P3 @ 850 MHz. Abstract Segmentation of the tracheo-bronchial tree of the lungs is notori, the complementary vascular tree of the lungs can be segmented. Furthermore, we modified our virtual endoscopy system

  3. The Stumbling Block in Lung Repair of Emphysema: Elastic Fiber Assembly

    E-Print Network [OSTI]

    Mecham, Robert

    The Stumbling Block in Lung Repair of Emphysema: Elastic Fiber Assembly Adrian Shifren and Robert P properties of the lung are largely determined by the connective tissue networks laid down during development. The macromolecules most important for lung mechanics and structural integrity are collagen, elastin

  4. A mechanochemical model for auto-regulation of lung airway surface layer volume

    E-Print Network [OSTI]

    Welch, Greg

    A mechanochemical model for auto-regulation of lung airway surface layer volume Gregory Herschlag a liquid in the lung. c Sources of stress (from cilia and breathe) and channel inhibitors are included. c in the lung airway surface layer (ASL) by coupling biochemical kinetics, transient ASL volume, and homeostatic

  5. Evaluation of Reconstructed Images of Regional Lung Changes Using a Model

    E-Print Network [OSTI]

    Adler, Andy

    Evaluation of Reconstructed Images of Regional Lung Changes Using a Model Robert P, Patterson1 A and Patterson 2004, Yang and Patterson 2010). In order to answer questions about regional lung changes, two regions were created in the posterior portion of the right lung where the resistivity can be independently

  6. Increased lung cancer risks are similar whether arsenic is ingested ALLAN H. SMITHa

    E-Print Network [OSTI]

    California at Berkeley, University of

    Increased lung cancer risks are similar whether arsenic is ingested or inhaled ALLAN H. SMITHa that inorganic arsenic was a human lung carcinogen based on studies involving exposure through inhalation. In 2004, IARC listed arsenic in drinking water as a cause of lung cancer, making arsenic the first

  7. ARTICLE doi:10.1038/nature12930 Alveolar progenitorand stem cells in lung

    E-Print Network [OSTI]

    Krasnow, Mark A.

    ARTICLE doi:10.1038/nature12930 Alveolar progenitorand stem cells in lung development, renewal or maintain AT1 and AT2 cells, and alveoli are a major site of lung cancer, the leading cause of cancer death2cellsisobservedfollowingbulklabellingofAT2cellpopulations8,9 . To circumvent slow turnover, lung injury models have been used and provide

  8. ORIGINAL ARTICLE Lung function in adults following in utero and childhood exposure

    E-Print Network [OSTI]

    California at Berkeley, University of

    ORIGINAL ARTICLE Lung function in adults following in utero and childhood exposure to arsenic water causes non-malignant lung disease, but nearly all data concern exposed adults. The desert city and long-term lung function. We present these preliminary findings because of the magnitude of the effects

  9. Neural Network Classifiers and Gene Selection Methods for Microarray Data on Human Lung Adenocarcinoma

    E-Print Network [OSTI]

    Narasimhan, Giri

    Neural Network Classifiers and Gene Selection Methods for Microarray Data on Human Lung with lung cancer gene expression data sets available from the CAMDA website. Many different classification several new methods for classifying gene expression data from lung cancer patients. Our approach uses

  10. GREIT: a unified approach to 2D linear EIT reconstruction of lung images

    E-Print Network [OSTI]

    Adler, Andy

    GREIT: a unified approach to 2D linear EIT reconstruction of lung images Andy Adler1 , John H the distribution of ventilation. However, most clinical and physiological research in lung EIT is done using older algorithm for lung EIT, called GREIT (Graz consensus Reconstruction algorithm for EIT). This paper describes

  11. SUPPLEMENTARY METHODS AND TABLES Drug transport from the blood into the lung tissue

    E-Print Network [OSTI]

    Kirschner, Denise

    1 SUPPLEMENTARY METHODS AND TABLES Drug transport from the blood into the lung tissue To study that enters the grid representing lung parenchyma via vascular sources, and diffuses among micro Once TNF inhibitors penetrate from blood into the lung tissue, they can bind TNF and thus block TNF

  12. LEVEL SET BASED RECONSTRUCTION ALGORITHM FOR EIT LUNG IMAGES Peyman Rahmati1

    E-Print Network [OSTI]

    Adler, Andy

    LEVEL SET BASED RECONSTRUCTION ALGORITHM FOR EIT LUNG IMAGES Peyman Rahmati1 , Manuchehr Soleimani2 the monitoring process. We represent lung images by applying the LSRM using difference solver and then compare in producing high quality, high contrast images of lung. Index Terms-- Inverse Problem, Electrical Impedence

  13. Biosynthesis and SupramolecularAssemblyof ProcollagenIV in Neonatal Lung

    E-Print Network [OSTI]

    Blumberg, Bruce

    Biosynthesis and SupramolecularAssemblyof ProcollagenIV in Neonatal Lung Bruce Blumberg, and the concentration of specific RNAs coding for pro- collagen IV were measured in neonatal rat lungs. Both decreased IV was followed in neonatal rat, mouse, and chick lungs, which actively elaborate endothelial

  14. Chronic rejection of a lung transplant is characterized by a profile of specific autoantibodies

    E-Print Network [OSTI]

    Domany, Eytan

    Chronic rejection of a lung transplant is characterized by a profile of specific autoantibodies Introduction Bronchiolitis obliterans syndrome (BOS) in lung trans- plant recipients is defined by progressive-term survival in lung transplant recipients2,3 and develops in nearly all patients to varying degrees.4

  15. ROBUST SEGMENTATION OF LUNG TISSUE IN CHEST CT SCANNING Amal Farag, James Graham and Aly Farag

    E-Print Network [OSTI]

    Louisville, University of

    ROBUST SEGMENTATION OF LUNG TISSUE IN CHEST CT SCANNING Amal Farag, James Graham and Aly Farag.edu ABSTRACT This paper deals with segmentation of the lung tissues from low dose CT (LDCT) scans of the chest. Goal is correct segmentation as well as maintaining the details of the lung region in the chest cavity

  16. Unsupervised localization of heart and lung regions in EIT images: a validation study

    E-Print Network [OSTI]

    Adler, Andy

    Unsupervised localization of heart and lung regions in EIT images: a validation study Damien an algorithm for automatic detection of heart and lung regions in a time series of EIT images. Candidate, it is important to accurately identify the relevant anatomical regions: the heart and lungs (H&L). Several methods

  17. Design and Analysis of a Wireless Nanosensor Network for Monitoring Human Lung Cells

    E-Print Network [OSTI]

    New South Wales, University of

    Design and Analysis of a Wireless Nanosensor Network for Monitoring Human Lung Cells Eisa Zarepour one day. In this paper, we design and analyse a WNSN for monitoring human lung cells. We find that influences the terahertz channel inside lung cells. The channel is characterised as a two-state channel

  18. A Framework for Automatic Segmentation of Lung Nodules from Low Dose Chest CT Scans

    E-Print Network [OSTI]

    Louisville, University of

    A Framework for Automatic Segmentation of Lung Nodules from Low Dose Chest CT Scans Ayman El-Baz1 the high accuracy of the proposed approach. 1 Introduction Because lung cancer is the most common cause 1, an initial LDCT slice is segmented with our algorithms introduced in [3] to isolate lung tissues

  19. Automatic Lung Segmentation of Volumetric Low-Dose CT Scans Using Graph Cuts

    E-Print Network [OSTI]

    Louisville, University of

    Automatic Lung Segmentation of Volumetric Low-Dose CT Scans Using Graph Cuts Asem M. Ali and Aly A for unsupervised segmentation of the lung region from low dose computed tomography (LDCT) images. We follow distribution model. To better spec- ify region borders between lung and chest, each empirical distribution

  20. American Studies What does it mean to be American? What are the origins of American

    E-Print Network [OSTI]

    Miles, Will

    trends, popular culture, environmental issues, science and religion Emily Mieras, Ph.D., College, politics, values and culture? How are our lives shaped by race, ethnicity, class and gender? These are some, politics, religion, the arts and the sciences to gain an understanding of the American experience and its