National Library of Energy BETA

Sample records for admi nistra tor

  1. Improving Tor performance through better path selection

    E-Print Network [OSTI]

    Chen, Fallon Ting

    2010-01-01

    S. Rollyson, “Improving tor onion routing client latency,”approach in “Improving Tor Onion Routing Client Latency” [C. Pasquale, Chair Tor, the Onion Router, is a popular

  2. Torchestra : reducing interactive trac delays over Tor

    E-Print Network [OSTI]

    Gopal, Deepika

    2012-01-01

    and Paul Syverson. Tor: The Second- Generation Onion Router.Hovav Shacham, Chair Tor is an onion routing network thatTor Architecture Tor stands for “The Onion Router” and is a

  3. A Tor Design Proposal November 30, 2005

    E-Print Network [OSTI]

    by the observation that Tor is currently difficult to install and that users are generally unfamiliar with onionFoxTor A Tor Design Proposal November 30, 2005 1.0 Design Overview ..........................................................................4 3.0 Tor User Interface Design

  4. DefenestraTor: Throwing out Windows in Tor Mashael AlSabah1

    E-Print Network [OSTI]

    Goldberg, Ian

    by source-routing their traffic through three Tor routers using onion routing [14]. Context. ConventionalDefenestraTor: Throwing out Windows in Tor Mashael AlSabah1 , Kevin Bauer1, , Ian Goldberg1 , Dirk, San Diego {dlmccoy,savage,voelker}@cs.ucsd.edu Abstract. Tor is one of the most widely used privacy

  5. A Tune-up for Tor: Improving Security and Performance in the Tor Network Robin Snader

    E-Print Network [OSTI]

    Borisov, Nikita

    -run replacement net- work using the second-generation onion routing design -- Tor [8] -- has been operationalA Tune-up for Tor: Improving Security and Performance in the Tor Network Robin Snader Department The Tor anonymous communication network uses self- reported bandwidth values to select routers

  6. DefenestraTor: Throwing Out Windows in Tor Mashael AlSabah1

    E-Print Network [OSTI]

    Voelker, Geoffrey M.

    by source-routing their traffic through three Tor routers using onion routing [14]. Context. ConventionalDefenestraTor: Throwing Out Windows in Tor Mashael AlSabah1 , Kevin Bauer1, , Ian Goldberg1 , Dirk, San Diego {dlmccoy,savage,voelker}@cs.ucsd.edu Abstract. Tor is one of the most widely used privacy

  7. Another Tor is possible Amadou Moctar Kane

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    a very little number of onion router (OR) in the Tor network (about 6000 OR for around 300,000 users path. More recently, Tor was created from the Onion Routing principles. It was originally FundedAnother Tor is possible Amadou Moctar Kane KSecurity, BP 47136, Dakar, Senegal. amadou1@gmail

  8. From Onions to Shallots: Rewarding Tor Relays with TEARS

    E-Print Network [OSTI]

    From Onions to Shallots: Rewarding Tor Relays with TEARS Rob Jansen1 , Andrew Miller2 , Paul.ford@yale.edu Abstract. The Tor anonymity network depends on volunteers to oper- ate relays, and might offer higher be deployed in the existing Tor network or operate alongside it. 1 Introduction Tor is the most popular

  9. A revocable anonymity in Tor Amadou Moctar Kane

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    . 1 Introduction Tor (The Onion Router) is a free software designed for online anonymity and resistingA revocable anonymity in Tor Amadou Moctar Kane KSecurity, BP 47136, Dakar, Senegal. amadou1@gmail in Tor, which was presented in our recent paper entitled "Another Tor is possible". Compared

  10. A TorPath to TorCoin: Proof-of-Bandwidth Altcoins for Compensating Relays

    E-Print Network [OSTI]

    Coins, so that anyone can verify a TorCoin by checking the blockchain. #12;2 Motivation and Related Work

  11. Enhancing Tor Performance For Bandwidth-Intensive Applications

    E-Print Network [OSTI]

    of the feedback control inherent in Tor's approach to load management ­ namely, probing and circuit selection. We

  12. Enhancing Tor Performance For BandwidthIntensive Applications +

    E-Print Network [OSTI]

    of the feedback control inherent in Tor's approach to load management -- namely, probing and circuit selection. We

  13. Challenges in protecting Tor hidden services from botnet abuse

    E-Print Network [OSTI]

    Hopper, Nicholas J.

    Challenges in protecting Tor hidden services from botnet abuse Nicholas Hopper University of Minnesota, Minneapolis, MN USA hopper@cs.umn.edu Abstract. In August 2013, the Tor network experienced and control server as a Tor hidden service, so that all infected nodes contacted the command and control

  14. The Path Less Travelled: Overcoming Tor's Bottlenecks with Traffic Splitting

    E-Print Network [OSTI]

    Goldberg, Ian

    The Path Less Travelled: Overcoming Tor's Bottlenecks with Traffic Splitting Mashael AlSabah, Kevin of Computer Science University of Waterloo Abstract. Tor is the most popular low-latency anonymity network, Tor has a variety of performance problems that result in poor quality of service, a strong

  15. PIR-Tor: Scalable Anonymous Communication Using Private Information Retrieval

    E-Print Network [OSTI]

    Goldberg, Ian

    PIR-Tor: Scalable Anonymous Communication Using Private Information Retrieval Prateek Mittal1 Femi like Tor do not scale well as they require all users to maintain up-to- date information about all available Tor relays in the sys- tem. Current proposals for scaling anonymous commu- nication advocate

  16. Compromising Tor Anonymity Exploiting P2P Information Leakage

    E-Print Network [OSTI]

    Castelluccia, Claude

    communications. Whereas the cryptographic foundations of Tor, based on onion- routing [4,5,6,7], are knownCompromising Tor Anonymity Exploiting P2P Information Leakage Pere Manils, Abdelberi Chaabane attacks targeting BitTorrent users on top of Tor that reveal their real IP addresses. In a second step, we

  17. The Sniper Attack: Anonymously Deanonymizing and Disabling the Tor Network

    E-Print Network [OSTI]

    Johnson, Aaron

    }@informatik.hu-berlin.de Abstract--Tor is a distributed onion-routing network used for achieving anonymity and resisting censorship and transferring roughly 3 GiB/s in aggregate [8]. Tor uses onion routing [25] to route clients' traffic throughThe Sniper Attack: Anonymously Deanonymizing and Disabling the Tor Network Rob Jansen Florian

  18. Recruiting New Tor Relays with BRAIDS Rob Jansen Nicholas Hopper

    E-Print Network [OSTI]

    Hopper, Nicholas J.

    . INTRODUCTION Tor [53] uses Onion Routing [24] to create a practical sys- tem for low-latency anonymity [14Recruiting New Tor Relays with BRAIDS Rob Jansen Nicholas Hopper University of Minnesota Minneapolis, MN 55455 USA {jansen, hopper, kyd}@cs.umn.edu Yongdae Kim ABSTRACT Tor, a distributed Internet

  19. Throttling Tor Bandwidth Parasites Rob Jansen Paul Syverson

    E-Print Network [OSTI]

    Throttling Tor Bandwidth Parasites Rob Jansen Paul Syverson U.S. Naval Research Laboratory {rob.g.jansen, paul.syverson}@nrl.navy.mil Nicholas Hopper University of Minnesota hopper@cs.umn.edu Abstract Tor of the available network capacity is consumed by a small percentage of Tor users, resulting in severe service degra

  20. Identifying Proxy Nodes in a Tor Anonymization Circuit Sambuddho Chakravarty

    E-Print Network [OSTI]

    Keromytis, Angelos D.

    Identifying Proxy Nodes in a Tor Anonymization Circuit Sambuddho Chakravarty Columbia University, and effective mechanism that exposes the identity of Tor relays participating in a given circuit. Such an attack), we create observable fluctuations that propagate through the Tor network and the Internet to the end

  1. On the Security of the Tor Authentication Protocol

    E-Print Network [OSTI]

    Goldberg, Ian

    On the Security of the Tor Authentication Protocol Ian Goldberg David R. Cheriton School@cs.uwaterloo.ca Abstract. Tor is a popular anonymous Internet communication sys- tem, used by an estimated 250,000 users to anonymously exchange over five terabytes of data per day. The security of Tor depends on properly

  2. The Sniper Attack: Anonymously Deanonymizing and Disabling the Tor Network

    E-Print Network [OSTI]

    }@informatik.hu-berlin.de Abstract--Tor is a distributed onion-routing network used for achieving anonymity and resisting censorshipB/s in aggregate [4]. Tor uses onion routing [5] to route clients' traffic through a circuit of geo- graphicallyThe Sniper Attack: Anonymously Deanonymizing and Disabling the Tor Network Rob Jansen Florian

  3. Tor: The Second-Generation Onion Router Roger Dingledine

    E-Print Network [OSTI]

    Tor: The Second-Generation Onion Router Roger Dingledine The Free Haven Project arma a single multiply encrypted data structure (an onion) to lay each circuit, Tor now uses an incremental@itd.nrl.navy.mil Abstract We present Tor, a circuit-based low-latency anonymous com- munication service. This second

  4. Shining Light in Dark Places: Understanding the Tor Network

    E-Print Network [OSTI]

    Washington at Seattle, University of

    Shining Light in Dark Places: Understanding the Tor Network Damon McCoy1 , Kevin Bauer1 , Dirk used? (2) How is Tor being mis-used? (3) Who is using Tor? To sample the results, we show that web such as web browsing, file sharing, and instant messaging. Since its initial development, researchers have

  5. mTOR Signaling in Growth Control and Disease

    E-Print Network [OSTI]

    Laplante, Mathieu

    The mechanistic target of rapamycin (mTOR) signaling pathway senses and integrates a variety of environmental cues to regulate organismal growth and homeostasis. The pathway regulates many major cellular processes and is ...

  6. mTOR and cancer: many loops in one pathway

    E-Print Network [OSTI]

    Efeyan, Alejo

    The mammalian target of rapamycin (mTOR) is a master regulator of cell growth and division that responds to a variety of stimuli, including nutrient, energy, and growth factors. In the last years, a significant number of ...

  7. Notes on Use of VecTor Programs: The VecTor analysis programs operate in a DOS-environment. Various input files are created or

    E-Print Network [OSTI]

    Vecchio, Frank J.

    Notes on Use of VecTor Programs: The VecTor analysis programs operate in a DOS-environment. Various input files are created or edited using standard text editors; output files are similarly viewed using Works, and output results can be viewed using the post-processor Augustus. Each VecTor program requires

  8. Low-Cost Traffic Analysis of Tor Steven J. Murdoch and George Danezis

    E-Print Network [OSTI]

    Danezis, George

    .Murdoch,George.Danezis}@cl.cam.ac.uk Abstract Tor is the second generation Onion Router, supporting the anonymous transport of TCP streams over, available for public use, already has 50 nodes acting as onion routers (as of November 2004). Tor aimsLow-Cost Traffic Analysis of Tor Steven J. Murdoch and George Danezis University of Cambridge

  9. SkypeMorph: Protocol Obfuscation for Tor Bridges Hooman Mohajeri Moghaddam Baiyu Li

    E-Print Network [OSTI]

    Goldberg, Ian

    SkypeMorph: Protocol Obfuscation for Tor Bridges Hooman Mohajeri Moghaddam Baiyu Li Mohammad {hmohajer,b5li,mderakhs,iang}@cs.uwaterloo.ca ABSTRACT The Tor network is designed to provide users with low- latency anonymous communications. Tor clients build cir- cuits with publicly listed relays to anonymously

  10. Improving Tor using a TCP-over-DTLS Tunnel Joel Reardon

    E-Print Network [OSTI]

    Goldberg, Ian

    Improving Tor using a TCP-over-DTLS Tunnel Joel Reardon Google Switzerland GmbH Brandschenkestrasse. Waterloo, ON, Canada iang@cs.uwaterloo.ca Abstract The Tor network gives anonymity to Internet users by re. This interference greatly contributes to Tor's notorious latency problems. Our solution is to use a TCP

  11. (Nothing else) MATor(s): Monitoring the Anonymity of Tor's Path Selection

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    & Future Work 26 1 #12;1 Introduction The onion routing network Tor is a widely employed low(Nothing else) MATor(s): Monitoring the Anonymity of Tor's Path Selection Michael Backes1,2 Aniket we present MATOR: a framework for rigorously assessing the degree of anonymity in the Tor network

  12. IEEE TRANSACTIONS ON DEPENDABLE AND SECURE COMPUTING 1 Improving Security and Performance in the Tor

    E-Print Network [OSTI]

    Borisov, Nikita

    using the second-generation onion routing design -- Tor [3] -- has been operational for several years in the Tor Network through Tunable Path Selection Robin Snader and Nikita Borisov, Member, IEEE Abstract--The Tor anonymous communication network uses self-reported bandwidth values to select routers for building

  13. Usability of Anonymous Web Browsing: An Examination of Tor Interfaces and Deployability

    E-Print Network [OSTI]

    Van Oorschot, Paul

    --Privacy General Terms Human Factors, Security Keywords Anonymity, browsing, onion routing, privacy, Privoxy, TorUsability of Anonymous Web Browsing: An Examination of Tor Interfaces and Deployability Jeremy of Information and Technology (SITE) University of Ottawa cadams@site.uottawa.ca ABSTRACT Tor is a popular

  14. TorScan: Tracing Long-lived Connections and Differential Scanning Attacks

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    successor of the original Onion Routing Project. The Tor network is a low-latency anonymity network whichTorScan: Tracing Long-lived Connections and Differential Scanning Attacks Alex Biryukov, Ivan Pustogarov, Ralf-Philipp Weinmann University of Luxembourg Abstract. Tor is a widely used anonymity network

  15. On the risks of serving whenever you surf Vulnerabilities in Tor's blocking resistance design

    E-Print Network [OSTI]

    Hopper, Nicholas J.

    , the Tor network consists of roughly 2000 "Onion Routers" that voluntarily relay traffic between who can observe a Tor client's network connections and even control some Onion Routers shouldOn the risks of serving whenever you surf Vulnerabilities in Tor's blocking resistance design Jon

  16. XPay: Practical anonymous payments for Tor routing and other networked services

    E-Print Network [OSTI]

    Carbunar, Bogdan

    XPay: Practical anonymous payments for Tor routing and other networked services Yao Chen, Radu Sion for Tor. We then propose micro- payment protocols of increasingly complex requirements for networked overheads of under 4% and 0.9 ms respectively (in ORPay for Tor), provide full anonymity (both for payers

  17. An Improved Algorithm for Tor Circuit Scheduling Cheriton School of Computer Science

    E-Print Network [OSTI]

    Goldberg, Ian

    Terms Measurement, Performance, Security Keywords Tor, latency, onion routing Permission to make digitalAn Improved Algorithm for Tor Circuit Scheduling Can Tang Cheriton School of Computer Science Science University of Waterloo Waterloo, ON, Canada iang@cs.uwaterloo.ca ABSTRACT Tor is a popular

  18. Aldo Morselli, INFN Roma Tor Vergata 1 Search for Dark Matter in the Sky

    E-Print Network [OSTI]

    Morselli, Aldo

    Aldo Morselli, INFN Roma Tor Vergata 1 Search for Dark Matter in the Sky Aldo Morselli INFN Roma Tor Vergata 14 Jun 2012 Dark Side of the Univers 2012 Buzios 10-15 June #12;Aldo Morselli, INFN Roma press/web releases. #12;Aldo Morselli, INFN Roma Tor Vergata 10 The Fermi LAT gamma-ray sky 3-year all

  19. Power Transformer faulT DeTecTor

    E-Print Network [OSTI]

    Mucina, Ladislav

    Power Transformer faulT DeTecTor Summary of technology Power transformers are major parts of the power distribution network, used to step up and step down voltages for transmission between power stations and electricity consumers. Transformers are prone to failure due to external damage or general

  20. Valeria Cardellini Universit di Roma "Tor Vergata," Italy

    E-Print Network [OSTI]

    Buyya, Rajkumar

    "Tor Vergata," Italy Kalinka Regina Lucas Jaquie Castelo Branco Universidade de São Paulo, Brazil Júlio Cezar Estrella Universidade de São Paulo, Brazil Francisco José Monaco Universidade de São Paulo, Brazil: Jamie Snavely Cover Design: Nick Newcomer Published in the United States of America by Information

  1. One Bad Apple Spoils the Bunch: Exploiting P2P Applications to Trace and Profile Tor Users

    E-Print Network [OSTI]

    Castelluccia, Claude

    that a source wants to leak top secret documents anonymously. It is considered secure to do so through Tor using uses another insecure application on Tor. Is it then possible to associate the top secret documents.g., the one leaking top secret documents) with the IP address of a Tor user. This attack against Tor consists

  2. Selective ATP-Competitive Inhibitors of TOR Suppress Rapamycin-Insensitive Function of TORC2 in S. cerevisiae

    E-Print Network [OSTI]

    Liu, Qingsong

    The target of rapamycin (TOR) is a critical regulator of growth, survival, and energy metabolism. The allosteric TORC1 inhibitor rapamycin has been used extensively to elucidate the TOR related signal pathway but is limited ...

  3. Improving efficiency and simplicity of Tor circuit establishment and hidden services

    E-Print Network [OSTI]

    Improving efficiency and simplicity of Tor circuit establishment and hidden services Lasse Øverlier Code 5540, Washington, DC 20375 syverson@itd.nrl.navy.mil, http://chacs.nrl.navy.mil/ / http://www.onion in the Tor anonymizing network by using predistributed Diffie-Hellman values. We eliminate the use of RSA

  4. GSA TEAs ToRs (revised August 2014) Page 1 of 2

    E-Print Network [OSTI]

    Calgary, University of

    GSA TEAs ToRs (revised August 2014) Page 1 of 2 PURPOSE OF THE AWARD: Every year, the GSA presents;GSA TEAs ToRs (revised August 2014) Page 2 of 2 Successful applications will be kept for 2 years after

  5. GSA TEAs ToRs (revised August 2014) Page 1 of 2

    E-Print Network [OSTI]

    Calgary, University of

    GSA TEAs ToRs (revised August 2014) Page 1 of 2 PURPOSE OF THE AWARD: Every year, the GSA presents #12;GSA TEAs ToRs (revised August 2014) Page 2 of 2 Other Regulations: 1. The Teaching & Supervisory faith to remain for the full academic year. 2. The activities of the TEAs-administering committee

  6. Shadow: Running Tor in a Box for Accurate and Efficient Experimentation U.S. Naval Research Laboratory

    E-Print Network [OSTI]

    Shadow: Running Tor in a Box for Accurate and Efficient Experimentation Rob Jansen U.S. Naval@cs.umn.edu Abstract Tor is a large and popular overlay network providing both anonymity to its users and a platform Tor experimentation tech- niques are limited in scale, are inaccurate, or create results

  7. mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

    E-Print Network [OSTI]

    Peterson, Timothy R.

    The nutrient- and growth factor-responsive kinase mTOR complex 1 (mTORC1) regulates many processes that control growth, including protein synthesis, autophagy, and lipogenesis. Through unknown mechanisms, mTORC1 promotes ...

  8. Regulation of mTOR complex 1 in response to growth factors and nutrients

    E-Print Network [OSTI]

    Sancak, Yasemin S. (Yasemin Shechner)

    2010-01-01

    In multicellular organisms, cells ensure the simultaneous availability of growth factors and nutrients before they invest in cellular processes that lead to growth. The TOR kinase is a master regulator of cellular growth ...

  9. Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

    E-Print Network [OSTI]

    Sengupta, Shomit

    The large serine/threonine protein kinase mTOR regulates cellular and organismal homeostasis by coordinating anabolic and catabolic processes with nutrient, energy, and oxygen availability and growth factor signaling. Cells ...

  10. Concours d'entre ISFA 2013 Liste des candidats admis

    E-Print Network [OSTI]

    Maume-Deschamps, Véronique

    CHELLALI Karim DE BRIANCON Pauline DESCAMPS Henri DEVRIES Clémence DIARRASSOUBA Mamery FAUCHEUX Johan

  11. Free-Piston Diesel Engine Dynamics and Control Tor A. Johansen1, Olav Egeland

    E-Print Network [OSTI]

    Johansen, Tor Arne

    Free-Piston Diesel Engine Dynamics and Control Tor A. Johansen1, Olav Egeland , Erling Aa. Kv rner ASA, Postboks 169, N-1325 Lysaker, Norway. Abstract Free-piston diesel engines. This paper present a dynamic mathematical model of a free-piston diesel engine, a control oriented dynamic

  12. Konkuk University, August 27 2009 Aldo Morselli, INFN Roma Tor Vergata 1 Aldo Morselli

    E-Print Network [OSTI]

    Morselli, Aldo

    the galactic plane loss term: fragmentation loss term: radioactive decaydiffusion coefficient is function of rigidity diffusion coefficient in the impulse space, quasi-linear MHD: primary spectra injection index, August 27 2009 Aldo Morselli, INFN Roma Tor Vergata 16 Comparison between the cosmic rays and the Solar S

  13. Scineghe08 8-11/10/08 Aldo Morselli, INFN Roma Tor Vergata 1 Aldo Morselli

    E-Print Network [OSTI]

    Morselli, Aldo

    Dark Matter from Space #12;Scineghe08 8-11/10/08 Aldo Morselli, INFN Roma Tor Vergata 2 Dark Energy 76% CDM Baryons 4%Cold Dark Matter 20% Dark Matter in the era of precision cosmology CDM ~ 5 b #12: primary spectra injection index implemented in Galprop ( Strong & Moskalenko, available on the Web) #12

  14. Changing of the Guards: A Framework for Understanding and Improving Entry Guard Selection in Tor

    E-Print Network [OSTI]

    Goldberg, Ian

    utilizes special nodes called entry guards as each client's long-term entry point into the anonymityChanging of the Guards: A Framework for Understanding and Improving Entry Guard Selection in Tor network. While the use of entry guards provides clear and well-studied secu- rity benefits, it is unclear

  15. RapTOR: Automated sequencing library preparation and suppression for rapid pathogen characterization ( 7th Annual SFAF Meeting, 2012)

    ScienceCinema (OSTI)

    Lane, Todd [SNL

    2013-02-11

    Todd Lane on "RapTOR: Automated sequencing library preparation and suppression for rapid pathogen characterization" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

  16. Aldo Morselli, INFN, Sezione di Roma 2 & Universit di Roma Tor Vergata, aldo.morselli@roma2.infn.it 1 Dark Matter

    E-Print Network [OSTI]

    Morselli, Aldo

    .it 1 Search for Dark Matter with space experiments Aldo Morselli INFN & Università di Roma Tor Vergata 22 - June 2006 International Workshop The Dark Side of the Universe Madrid, June 20-24, 2006 #12;Aldo & Moskalenko, available on the Web) #12;Aldo Morselli, INFN, Sezione di Roma 2 & Università di Roma Tor Vergata

  17. Aldo Morselli, INFN Roma Tor Vergata Detector Techniques for Cosmology, Astroparticle and General Physics May 29 2015 1 Aldo Morselli

    E-Print Network [OSTI]

    Morselli, Aldo

    and General Physics Poster Review FRONTIER DETECTORS FOR FRONTIER PHYSICS 13th Pisa Meeting on Advanced and General Physics May 29 2015 2 The Tunka Radio Extension (Tunka-Rex) ­ Radio Measurements of Cosmic Rays Techniques for Cosmology, Astroparticle and General Physics : 24 Posters #12;Aldo Morselli, INFN Roma Tor

  18. Tools 10 , University of Southampton, July 1 2010 Aldo Morselli, INFN Roma Tor Vergata 1 Aldo Morselli

    E-Print Network [OSTI]

    Morselli, Aldo

    Tools 10 , University of Southampton, July 1 2010 Aldo Morselli, INFN Roma Tor Vergata 1 Aldo July 1 TOOLS 2010 - Tools for SUSY and the New Physics, Sharpening our Tools 29 June 2010 to 02 July 2010 University of Southampton #12;Tools 10 , University of Southampton, July 1 2010 Aldo Morselli

  19. mTOR phosphorylates IMP2 to promote IGF2 mRNA translation by internal ribosomal entry

    E-Print Network [OSTI]

    Dai, Ning

    Variants in the IMP2 (insulin-like growth factor 2 [IGF2] mRNA-binding protein 2) gene are implicated in susceptibility to type 2 diabetes. We describe the ability of mammalian target of rapamycin (mTOR) to regulate the ...

  20. The identification of the mTOR-regulated phosphoproteome and a mediator of feedback inhibition to P13K-Akt

    E-Print Network [OSTI]

    Hsu, Peggy Ping

    2011-01-01

    The mTOR protein kinase nucleates two complexes, mTORC1 and mTORC2. Collectively, the two complexes regulate processes important for cell growth and proliferation, including protein synthesis, autophagy, metabolism, and ...

  1. Rapamycin targeting mTOR and hedgehog signaling pathways blocks human rhabdomyosarcoma growth in xenograft murine model

    SciTech Connect (OSTI)

    Kaylani, Samer Z. [Division of Hematology and Oncology, Department of Pediatrics, University of Alabama at Birmingham, 1600 7th Avenue South, ACC 414, Birmingham, AL 35233 (United States)] [Division of Hematology and Oncology, Department of Pediatrics, University of Alabama at Birmingham, 1600 7th Avenue South, ACC 414, Birmingham, AL 35233 (United States); Xu, Jianmin; Srivastava, Ritesh K. [Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, 1530 3rd Avenue South, VH 509, Birmingham, AL 35294-0019 (United States)] [Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, 1530 3rd Avenue South, VH 509, Birmingham, AL 35294-0019 (United States); Kopelovich, Levy [Division of Cancer Prevention, National Cancer Institute, Bethesda (United States)] [Division of Cancer Prevention, National Cancer Institute, Bethesda (United States); Pressey, Joseph G. [Division of Hematology and Oncology, Department of Pediatrics, University of Alabama at Birmingham, 1600 7th Avenue South, ACC 414, Birmingham, AL 35233 (United States)] [Division of Hematology and Oncology, Department of Pediatrics, University of Alabama at Birmingham, 1600 7th Avenue South, ACC 414, Birmingham, AL 35233 (United States); Athar, Mohammad, E-mail: mathar@uab.edu [Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, 1530 3rd Avenue South, VH 509, Birmingham, AL 35294-0019 (United States)] [Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, 1530 3rd Avenue South, VH 509, Birmingham, AL 35294-0019 (United States)

    2013-06-14

    Graphical abstract: Intervention of poorly differentiated RMS by rapamycin: In poorly differentiated RMS, rapamycin blocks mTOR and Hh signaling pathways concomitantly. This leads to dampening in cell cycle regulation and induction of apoptosis. This study provides a rationale for the therapeutic intervention of poorly differentiated RMS by treating patients with rapamycin alone or in combination with other chemotherapeutic agents. -- Highlights: •Rapamycin abrogates RMS tumor growth by modulating proliferation and apoptosis. •Co-targeting mTOR/Hh pathways underlie the molecular basis of effectiveness. •Reduction in mTOR/Hh pathways diminish EMT leading to reduced invasiveness. -- Abstract: Rhabdomyosarcomas (RMS) represent the most common childhood soft-tissue sarcoma. Over the past few decades outcomes for low and intermediate risk RMS patients have slowly improved while patients with metastatic or relapsed RMS still face a grim prognosis. New chemotherapeutic agents or combinations of chemotherapies have largely failed to improve the outcome. Based on the identification of novel molecular targets, potential therapeutic approaches in RMS may offer a decreased reliance on conventional chemotherapy. Thus, identification of effective therapeutic agents that specifically target relevant pathways may be particularly beneficial for patients with metastatic and refractory RMS. The PI3K/AKT/mTOR pathway has been found to be a potentially attractive target in RMS therapy. In this study, we provide evidence that rapamycin (sirolimus) abrogates growth of RMS development in a RMS xenograft mouse model. As compared to a vehicle-treated control group, more than 95% inhibition in tumor growth was observed in mice receiving parenteral administration of rapamycin. The residual tumors in rapamycin-treated group showed significant reduction in the expression of biomarkers indicative of proliferation and tumor invasiveness. These tumors also showed enhanced apoptosis. Interestingly, the mechanism by which rapamycin diminished RMS tumor growth involved simultaneous inhibition of mTOR and hedgehog (Hh) pathways. Diminution in these pathways in this model of RMS also inhibited epithelial mesenchymal transition (EMT) which then dampened the invasiveness of these tumors. Our data provide bases for using rapamycin either alone or in combination with traditional chemotherapeutic drugs to block the pathogenesis of high risk RMS.

  2. The Cleveland MuseuM of naTural hisTorY nuMber 56 GEOLOGY AND PALEONTOLOGY OF LEMUDONG'O, KENYA

    E-Print Network [OSTI]

    Hlusko, Leslea J.

    The Cleveland MuseuM of naTural hisTorY nuMber 56 GEOLOGY AND PALEONTOLOGY OF LEMUDONG'O, KENYA J. Hlusko GEOLOGY, GEOCHEMISTRY, AND STRATIGRAPHY OF THE LEMUDONG'O FORMATION, KENYA RIFT VALLEY 53: Cultural and Physical Anthropology; Archaeology; Botany; Geology; Paleobotany; Invertebrate and Vertebrate

  3. Integrated Dynamic Analysis of Floating Offshore Wind Turbines Bjrn Skaare*, Tor David Hanson*, Finn Gunnar Nielsen*, Rune Yttervik*, Anders Melchior Hansen**,

    E-Print Network [OSTI]

    Integrated Dynamic Analysis of Floating Offshore Wind Turbines Bjørn Skaare*, Tor David Hanson of floating wind turbines exposed to forces from wind, waves and current has been developed for Hydro Oil & Energy's floating wind turbine concept, HYWIND. Two existing, independent, computer program systems

  4. Aldo Morselli, INFN & Universit di Roma Tor Vergata, aldo.morselli@roma2.infn.it 1 Dark Matter Indirect Search

    E-Print Network [OSTI]

    Morselli, Aldo

    Aldo Morselli, INFN & Università di Roma Tor Vergata, aldo.morselli@roma2.infn.it 1 Dark Matter Indirect Search : News from the sky Prospects for the detection of Dark Matter CIECEM Matalacañs, Spain & Moskalenko, available on the Web) semi-analitical solution: Maurin et al, astro-ph/0101231 #12;Aldo Morselli

  5. MicroRNA-101 mediates the suppressive effect of laminar shear stress on mTOR expression in vascular endothelial cells

    SciTech Connect (OSTI)

    Chen, Kui; Fan, Wendong; Wang, Xing; Ke, Xiao [Division of Cardiology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080 (China)] [Division of Cardiology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080 (China); Wu, Guifu, E-mail: eecpchina@yahoo.com.cn [Key Laboratory on Assisted Circulation, Ministry of Health, Guangzhou 510080 (China)] [Key Laboratory on Assisted Circulation, Ministry of Health, Guangzhou 510080 (China); Hu, Chengheng, E-mail: huchenghengpci@yahoo.com.cn [Division of Cardiology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080 (China)] [Division of Cardiology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080 (China)

    2012-10-12

    Highlights: Black-Right-Pointing-Pointer Laminar shear stress upregulates miR-101 expression in vascular endothelial cells. Black-Right-Pointing-Pointer miR-101 represses mTOR expression through a specific 3 Prime UTR binding site. Black-Right-Pointing-Pointer Overexpression of miR-101 inhibits G1/S transition and endothelial cell proliferation. Black-Right-Pointing-Pointer Blockade of miR-101 attenuates the suppressive effect of laminar flow on mTOR expression. -- Abstract: Shear stress associated with blood flow plays an important role in regulating gene expression and cell function in endothelial cells (ECs). MicroRNAs (miRNAs) are highly conserved, small non-coding RNAs that negatively regulate the expression of target genes by binding to the mRNA 3 Prime -untranslated region (3 Prime UTR) at the posttranscriptional level involved in diverse cellular processes. This study demonstrates that microRNA-101 in response to laminar shear stress (LSS) is involved in the flow regulation of gene expression in ECs. qRT-PCR analysis showed that miR-101 expression was significantly upregulated in human umbilical vein endothelial cells (HUVECs) exposed to 12 dyn/cm{sup 2} laminar shear stress for 12 h. We found that transfection of miR-101 significantly decreased the luciferase activity of plasmid reporter containing the 3 Prime UTR of mammalian target of rapamycin (mTOR) gene. Western analysis revealed that the protein level of mTOR was significantly reduced in ECs transfected with miR-101. Furthermore, miR-101 overexpression induced cell cycle arrest at the G1/S transition and suppressed endothelial cell proliferation. Finally, transfection of miR-101 inhibitors attenuated the suppressive effects of LSS on mTOR expression, which identified the efficacy of loss-of-function of miR-101 in laminar flow-treated ECs. In conclusion, we have demonstrated that upregulation of miR-101 in response to LSS contributes to the suppressive effects of LSS on mTOR expression and EC proliferation. These studies advance our understanding of the posttranscriptional mechanisms by which shear stress modulates endothelial homeostasis.

  6. Vorinostat, an HDAC inhibitor attenuates epidermoid squamous cell carcinoma growth by dampening mTOR signaling pathway in a human xenograft murine model

    SciTech Connect (OSTI)

    Kurundkar, Deepali; Srivastava, Ritesh K.; Chaudhary, Sandeep C. [Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, 1530 3rd Avenue South, VH 509, Birmingham, AL 35294-0019 (United States)] [Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, 1530 3rd Avenue South, VH 509, Birmingham, AL 35294-0019 (United States); Ballestas, Mary E. [Department of Pediatrics Infectious Disease, Children's of Alabama, School of Medicine, University of Alabama at Birmingham, AL (United States)] [Department of Pediatrics Infectious Disease, Children's of Alabama, School of Medicine, University of Alabama at Birmingham, AL (United States); Kopelovich, Levy [Division of Cancer Prevention, National Cancer Institute, 6130 Executive Blvd., Suite 2114, Bethesda, MD 20892 (United States)] [Division of Cancer Prevention, National Cancer Institute, 6130 Executive Blvd., Suite 2114, Bethesda, MD 20892 (United States); Elmets, Craig A. [Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, 1530 3rd Avenue South, VH 509, Birmingham, AL 35294-0019 (United States)] [Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, 1530 3rd Avenue South, VH 509, Birmingham, AL 35294-0019 (United States); Athar, Mohammad, E-mail: mathar@uab.edu [Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, 1530 3rd Avenue South, VH 509, Birmingham, AL 35294-0019 (United States)] [Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, 1530 3rd Avenue South, VH 509, Birmingham, AL 35294-0019 (United States)

    2013-01-15

    Histone deacetylase (HDAC) inhibitors are potent anticancer agents and show efficacy against various human neoplasms. Vorinostat is a potent HDAC inhibitor and has shown potential to inhibit growth of human xenograft tumors. However, its effect on the growth of skin neoplasm remains undefined. In this study, we show that vorinostat (2 ?M) reduced expression of HDAC1, 2, 3, and 7 in epidermoid carcinoma A431 cells. Consistently, it increased acetylation of histone H3 and p53. Vorinostat (100 mg/kg body weight, IP) treatment reduced human xenograft tumor growth in highly immunosuppressed nu/nu mice. Histologically, the vorinostat-treated tumor showed features of well-differentiation with large necrotic areas. Based on proliferating cell nuclear antigen (PCNA) staining and expression of cyclins D1, D2, E, and A, vorinostat seems to impair proliferation by down-regulating the expression of these proteins. However, it also induced apoptosis. The mechanism by which vorinostat blocks proliferation and makes tumor cells prone to apoptosis, involved inhibition of mTOR signaling which was accompanied by reduction in cell survival AKT and extracellular-signal regulated kinase (ERK) signaling pathways. Our data provide a novel mechanism-based therapeutic intervention for cutaneous squamous cell carcinoma (SCC). Vorinostat may be utilized to cure skin neoplasms in organ transplant recipient (OTR). These patients have high morbidity and surgical removal of these lesions which frequently develop in these patients, is difficult. -- Highlights: ? Vorinostat reduces SCC growth in a xenograft murine model. ? Vorinostat dampens proliferation and induces apoptosis in tumor cells. ? Diminution in mTOR, Akt and ERK signaling underlies inhibition in proliferation. ? Vorinostat by inhibiting HDACs inhibits epithelial–mesenchymal transition.

  7. Ascofuranone suppresses EGF-induced HIF-1? protein synthesis by inhibition of the Akt/mTOR/p70S6K pathway in MDA-MB-231 breast cancer cells

    SciTech Connect (OSTI)

    Jeong, Yun-Jeong; Cho, Hyun-Ji [Research Institute of Biomedical Engineering and Department of Medicine, Catholic University of Daegu School of Medicine, Daegu 705-718 (Korea, Republic of); Magae, Junji [Magae Bioscience Institute, 49-4 Fujimidai, Tsukuba 300-1263 (Japan); Lee, In-Kyu [Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu 700-721 (Korea, Republic of); Park, Keun-Gyu, E-mail: kpark@knu.ac.kr [Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu 700-721 (Korea, Republic of); Chang, Young-Chae, E-mail: ycchang@cu.ac.kr [Research Institute of Biomedical Engineering and Department of Medicine, Catholic University of Daegu School of Medicine, Daegu 705-718 (Korea, Republic of)

    2013-12-15

    Hypoxia-inducible factor (HIF)-1 plays an important role in tumor progression, angiogenesis and metastasis. In this study, we investigated the potential molecular mechanisms underlying the anti-angiogenic effect of ascofuranone, an isoprenoid antibiotic from Ascochyta viciae, in epidermal growth factor (EGF)-1 responsive human breast cancer cells. Ascofuranone significantly and selectively suppressed EGF-induced HIF-1? protein accumulation, whereas it did not affect the expression of HIF-1?. Furthermore, ascofuranone inhibited the transcriptional activation of vascular endothelial growth factor (VEGF) by reducing protein HIF-1?. Mechanistically, we found that the inhibitory effects of ascofuranone on HIF-1? protein expression are associated with the inhibition of synthesis HIF-1? through an EGF-dependent mechanism. In addition, ascofuranone suppressed EGF-induced phosphorylation of Akt/mTOR/p70S6 kinase, but the phosphorylation of ERK/JNK/p38 kinase was not affected by ascofuranone. These results suggest that ascofuranone suppresses EGF-induced HIF-1? protein translation through the inhibition of Akt/mTOR/p70S6 kinase signaling pathways and plays a novel role in the anti-angiogenic action. - Highlights: • Inhibitory effect of ascofuranone on HIF-1? expression is EGF-specific regulation. • Ascofuranone decreases HIF-1? protein synthesis through Akt/mTOR pathways. • Ascofuranone suppresses EGF-induced VEGF production and tumor angiogenesis.

  8. Office of Admissions and Scholarships 250 Hannah Administration Building East Lansing, Michigan 48824-0590 (517) 355-8332 admis@msu.edu

    E-Print Network [OSTI]

    niveles de ahorro actuales. Si necesita ayuda financiera, su primer paso es presentar una Free Application

  9. Targeting mTOR in Pancreatic Cancer

    E-Print Network [OSTI]

    Soares, Heloisa Prado

    2015-01-01

    Parsons J, Kern SE. Progression model for pancreatic cancer.Clinical Cancer Research. 2000;6(N8):2969-72.Martinelli P. Pancreatic Cancer Development and Progression:

  10. mTOR Signalling in Health and Disease 437 A brief history of TOR

    E-Print Network [OSTI]

    Halazonetis, Thanos

    hygroscopicus that was found to produce a secondary metabolite, now known as rapamycin, with potent antifungal plants date back to 3000 BCE. Building on such ob- servations, systematic `bioprospecting' expeditions expedition, in the 1960s, to Easter Island (Rapa Nui in the native language) to gather plant and soil samples

  11. Electrostatic Interactions in RNA Aminoglycosides Hai Wang and Yitzhak Tor*

    E-Print Network [OSTI]

    Gates, Kent. S.

    .7) to ethanolamine (pKa ) 9.50)10 indicates that the presence of a vicinal hydroxyl lowers the basicity of the amine.e., amino and hydroxyl groups) and the RNA backbone and/or heterocyclic bases are likely to occur.8 that are predominantly charged at pH 7.0.9 The role played by the hydroxyl groups is much less clear. Kanamycin B is 20

  12. Aldo Morselli, INFN Roma Tor Vergata! 1! Aldo Morselli

    E-Print Network [OSTI]

    Morselli, Aldo

    Vitale, Aldo Morselli, the Fermi/LAT Collaboration Proceedings of the 2009 Fermi Symposium, 6 pages, e Center V.Vitale, A.Morselli, the Fermi/LAT Collaboration Nuclear Instruments and Methods in PhysicsV and increasing to 20% at 10 GeV! V.Vitale, A.Morselli, Fermi Coll. NIM A630 (2011) 147, arXiv:0912.3828 #12;Aldo

  13. Staying FIT: Efficient Load Shedding Techniques for Distributed Stream Processing

    E-Print Network [OSTI]

    . Bottlenecks slow down processing and network transmission, and cause delayed outputs. Load management has been. Common load management techniques include adaptive load distribution, admis- sion control, and load

  14. FNOV SEA-2015-01

    Broader source: Energy.gov (indexed) [DOE]

    Admi nistrator, National Nuclear Security Administration Wash ington, DC 20585 VIA OVERNIGHT CARRIER Dr. Paul J. Hommert President Sandia Corporation 1515 Eubank SE July 13, 2015...

  15. Energy-based Control of a Distributed Solar Collector Tor A. Johansena

    E-Print Network [OSTI]

    Johansen, Tor Arne

    . An energy-based controller is derived using internal energy as a storage function and controlled variable energy developed by the eld is pumped to the top of the thermal storage tank, see Figure 1, whereupon and approximated by a - nite dimensional model, the frequency response contains anti-resonant modes near

  16. eter Agre is a medical doc-tor, professor and molecu-

    E-Print Network [OSTI]

    Wechsler, Risa H.

    To Work · Dr. Mark Zoback: Geologist Finds No Fault With Fracking · Dr. Carol Greider: Unraveling DNA was successfully drilled through Continued on page 4 Dr. Mark Zoback: Geologist Finds No Fault With Fracking Dr

  17. Myers-Briggs Type indicaTor (MBTI) ESFP(Extraversion, Sensing, Feeling, Perceiving)

    E-Print Network [OSTI]

    Saskatchewan, University of

    to work well on a team and infuse fun into any aspect of their work. ISTJ ISFJ INFJ INTJ ISTP ISFP INFP

  18. Myers-Briggs Type indicaTor (MBTI) INFP(Introversion, Intuition, Feeling, Perceiving)

    E-Print Network [OSTI]

    Saskatchewan, University of

    a talented writer that infuses their personality into their writing. They tend to use their imaginations

  19. CellFlood: Attacking Tor Onion Routers on the Cheap Marco V. Barbera1

    E-Print Network [OSTI]

    Keromytis, Angelos D.

    . As a way to mitigate the effect of this attack, we propose to use a client puzzle-based technique the design and implementation of an effective solution to the problem that relies on cryptographic client]. Such an attack could be used to either significantly degrade the users' perceived quality of service, which would

  20. Molecular characterization of Vibrio cholerae outbreak strains with altered El Tor biotype from southern India

    E-Print Network [OSTI]

    Goel, A. K.; Jain, M.; Kumar, P.; Jiang, S. C.

    2010-01-01

    of antibiotic resistance genes in many bacteria (Hall andbacteria (Beaber and Waldor 2004). In SXT cons- tins, the antibiotic resistance

  1. A Conceptual Framework for Semantic Case-based Safety Analysis Olawande Daramola, Tor Stlhane

    E-Print Network [OSTI]

    .biffl}@tuwien.ac.at Abstract Hazard and Operability (HAZOP) Analysis and Fail- ure Mode and Effect Analysis (FMEA) are among-based framework for safety analy- sis, which facilitates the reuse of previous HAZOP and FMEA experiences in order application. Key words: Safety analysis, HAZOP, FMEA, ontology, requirements, case-based reasoning, natural

  2. C:\\eudora\\attach\\TOR90 dcw.doc 2 /9/ 01 AUSTRALIAN NATIONAL UNIVERSITY

    E-Print Network [OSTI]

    Chen, Ying

    better do some routine maintenance including inspection of chains, idlers, bearings, oilers, resistor leads and inductors. Other maintenance items included replacement of eight column posts, repopulate both, by 180 deg. It was also thought that the absorbent chambers in the terminal turbo pump manifold should

  3. Universit`a di Roma "Tor Vergata" Young Algebra Seminar 20012002

    E-Print Network [OSTI]

    Roma Tor Vergata, Università di

    enumerativo un po' pi`u compicato: quante curve razion- ali di grado d passano per n punti? Per d = 1, 2, si

  4. Valencia, July 22 2010 Aldo Morselli, INFN Roma Tor Vergata 1 Aldo Morselli

    E-Print Network [OSTI]

    Morselli, Aldo

    and increases linearly with the distance from the galactic plane loss term: fragmentation loss term: radioactive decaydiffusion coefficient is function of rigidity diffusion coefficient in the impulse space, quasi-linear MHD rays and the Solar System element composition, both relative to Carbon Cosmic Rays Solar System #12

  5. XI Elba Workshop 2010 June 23 Aldo Morselli, INFN Roma Tor Vergata 1 Aldo Morselli

    E-Print Network [OSTI]

    Morselli, Aldo

    with the distance from the galactic plane loss term: fragmentation loss term: radioactive decaydiffusion coefficient is function of rigidity diffusion coefficient in the impulse space, quasi-linear MHD: primary spectra rays and the Solar System element composition, both relative to Carbon Cosmic Rays Solar System #12;XI

  6. Operating Regime Based Process Modeling and Identi -Tor A. Johansen1 and Bjarne A. Foss2

    E-Print Network [OSTI]

    Foss, Bjarne A.

    Department of Engineering Cybernetics Norwegian Institute of Technology N-7034 Trondheim Norway Revised from chemical engineering are used to highlight the exibility and power of the framework. KEYWORDS A. Johansen and Bjarne A. Foss 1 INTRODUCTION In engineering, there are two fundamentally di erent

  7. Paolo Podio-Guidugli Universit di Roma TorVergata, Italy

    E-Print Network [OSTI]

    Gilardi, Gianni

    Ruby Laser. 3/3 #12;Laser­Matter Interaction In poor-man solid state physics, L­M interaction is a play Amplification by Stimulated Emission of Radiation · CW Laser Continuous Wave Laser, produces a continu- ous with three types of characters: photons, electrons, and lattice atoms; the net outcome of their interaction

  8. Gain Scheduled Control of a Solar Power Plant Tor A. Johansen1

    E-Print Network [OSTI]

    Johansen, Tor Arne

    to a pilot-scale solar power plant is described. A eld of parabolic collectors focus the solar radiation onto, is described. A eld of parabolic collectors focus the solar radiation onto a tube where oil is pumped through. Figures 1-2 shows photographs of the Acurex plant. The eld is composed of 480 distributed solar collectors

  9. Aldo Morselli, INFN Roma Tor Vergata! 1! Future experiments in space and on ground for

    E-Print Network [OSTI]

    Morselli, Aldo

    the center of the Milky Way with the Fermi-Large Area Telescope Vincenzo Vitale, Aldo Morselli, the Fermi for Dark Matter with Fermi Large Area Telescope: the Galactic Center V.Vitale, A.Morselli, the Fermi% at 560 MeV and increasing to 20% at 10 GeV! V.Vitale, A.Morselli, Fermi Coll. NIM A630 (2011) 147, ar

  10. Aldo Morselli, INFN Roma Tor Vergata 1 High-Energy Astrophysics above 10 MeV

    E-Print Network [OSTI]

    Morselli, Aldo

    .Paggi, A.Cavaliere, A.Lionetto, A.Morselli, V.Vitale. A&A 510, A90 (2010) [arXiv:0912.1766] All profiles catalog sources best diffuse model and isotropic emission data (stat. error) preliminary V.Vitale, A (blue area) of the LAT is ~10% at 100 MeV, decreasing to 5% at 560 MeV and increasing to 20% at 10 GeV V.Vitale

  11. LNF, Stages per studenti, 16 Giugno 2010 Aldo Morselli, INFN Roma Tor Vergata 1 Aldo Morselli

    E-Print Network [OSTI]

    Morselli, Aldo

    V: energia acquistata da un elettrone che attraverso un campo elettrico di 1 Volt) ) #12;LNF, Stages per oggetti di 0,001 mm servono lunghezze d'onda piu' piccole , cioè quanti di luce (fotoni ) di energia più elevata · che perturbano il sistema ( cioè forniscono energia al sistema ) · in pratica piu' precisa è la

  12. a J. C. Clarke, Contract FEOM 8 J. P. Morgan, Assist tor, Pznduction Division

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and700, 1. .&. ' , cMarchW W e e l lJ. C.

  13. Arrt du 31 juillet 2009 relatif au diplme d'Etat d'infirmier TITRE II : DISPENSES DE SCOLARITE

    E-Print Network [OSTI]

    Jeanjean, Louis

    Arrêté du 31 juillet 2009 relatif au diplôme d'Etat d'infirmier TITRE II : DISPENSES DE SCOLARITE à la direction de l'institut de formation en soins infirmiers où ils sont admis dans les délais

  14. facility, C nsfer guide

    E-Print Network [OSTI]

    Karonis, Nicholas T.

    and hospitali ition, Dietet on, foods, an ration for fu ration. Stude ce managem urses in gen rovides stud ts teraction, re groundwor ministration u pitality Admi ureate requ f hospitality event manag s knowledge

  15. Noise Injection for Search Privacy Protection

    E-Print Network [OSTI]

    Ye, Shaozhi; Wu, S F; Pandey, Raju; Chen, Hao

    2009-01-01

    P. Syverson, “Tor: the second- generation onion router,” inengines. Onion routing [22] and its successor TOR [23

  16. Separation Processes, Second Edition

    E-Print Network [OSTI]

    King, C. Judson

    1980-01-01

    those discussed for staged contac- tors in Chap. 10. Stockarliquid and liquid- liquid contac- tors are reported by Perry

  17. Aldo Morselli, INFN Roma Tor Vergata, aldo.morselli@roma2.infn.it 1 Aldo Morselli

    E-Print Network [OSTI]

    Morselli, Aldo

    with the distance from the galactic plane loss term: fragmentation loss term: radioactive decaydiffusion coefficient is function of rigidity diffusion coefficient in the impulse space, quasi-linear MHD: primary spectra: Diffusion coeff., halo size, Alfvén speed, convection velocity... Energy markers: Reacceleration, solar

  18. SEMINARIEPROGRAM FoKult ht 2013 Tor-fre 29-30 aug Internat om inledningar p Sby Steri.

    E-Print Network [OSTI]

    Nilsson: Byzantion ­ Konstantinopel ­ Istanbul: kulturmöten i tid och rum. (AA) Mån 16 sept, kl 15 Böckerman Fre 6 dec, kl 10-12 Textseminarium: Daniel Strand Fre 20 dec, kl 10-12 Textseminarium: Niklas Haga

  19. EXPERIMENT GUIDE SUP E R CON D U C TOR DE M ON S T RA T ION S

    E-Print Network [OSTI]

    Bayindir, Mehmet

    Energy Storage (Battery) Ring Measuring Critical Temperature with the Susceptibility Probe Where do we go. USE AT YOUR OWN RISK. #12;TABLE OF CONTENTS 3 4 5 5 Introduction The Kits and their purpose Lecture

  20. MEMO RANUM FOR HUMAN RESOURCES DIRECTORS FROM: S~J\O~TOR OFFICE b:\HUMAN CAPITAL MANAGEMENT

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankADVANCED MANUFACTURING OFFICE INDUSTRIALU.S.LeadershipLumileds R&D ImpactsMARVINServices6, 2010 MEMO

  1. Hidden Identity-Based Signatures Aggelos Kiayias

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    primitive, we apply it to solve a problem of current onion- routing systems focusing on the Tor system-based schemes, Digital Signatures, Onion-routing, Tor, Wikipedia. 1 Introduction Anonymity and privacy consider the recent example of Tor [Tor], an onion-routing system, and how Tor traffic is currently handled

  2. Data Mining and Internet Profiling: Emerging Regulatory and Technological Approaches

    E-Print Network [OSTI]

    Schwartz, Paul M.; Lee, Ronald D.; Rubinstein, Ira

    2008-01-01

    Paul Syverson, Tor: The Second- Generation Onion Router (Augthe “Tor” implementation of second-generation onion routing.tor-design.pdf (visited Jan 12, 2008) (describing a second-generation onion-

  3. In Pursuit of Privacy on a Public Internet

    E-Print Network [OSTI]

    Mendonca, Marc

    2012-01-01

    application data. Tor Onion Routing Onion routing[22, 18],including web proxies and Tor onion routing, and found mostand P. Syverson. Tor: The second-generation onion router. In

  4. Techniques for the Dynamic Randomization of Network Attributes

    E-Print Network [OSTI]

    Chavez, Adrian; Stout, William M.S.; Peisert, Sean

    2015-01-01

    Syverson, “Tor: The second- generation onion router,” 2004.Tor is one of the most popular implementations used for onionTor network to determine the endpoints in communication. While onion

  5. Efficacy of the investigational mTOR kinase inhibitor MLN0128 / INK128 in models of B-cell acute lymphoblastic leukemia

    E-Print Network [OSTI]

    2012-01-01

    and xenograft experiments with human leukemia samples NIH-PAculture experiments, hTERT-immortalized human marrow stromal

  6. Efficacy of the investigational mTOR kinase inhibitor MLN0128 / INK128 in models of B-cell acute lymphoblastic leukemia

    E-Print Network [OSTI]

    2012-01-01

    were injected intravenously into NOD-SCID-?c ?/? (NSG) mice.were injected intravenously into NOD-SCID?c ?/? (NSG) mice

  7. Identification of novel substrates of the energy-sensing kinase, AMP-activated protein kinase, and regulation of mTOR signaling during energy stress and mitosis

    E-Print Network [OSTI]

    Gwinn, Dana Meredith

    2011-01-01

    Insulin modulates gluconeogenesis by inhibition of theof AMPK on hepatic gluconeogenesis are mediated by directregulation of gluconeogenesis. In contrast, lipogenesis is

  8. Targeting the genetic alterations of the PI3K-AKT-mTOR pathway: its potential use in the treatment of bladder cancers.

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    , Lopes, & Soares, 2012; Shaw & Cantley, 2006). It is also involved in the resistance to "conventional Aromatic Hydrocarbons). aromatic amines are essentially metabolized by the liver and metabolites are conventional urothelial carcinoma, the other subtype being urothelial carcinoma with aberrantdifferentiation

  9. The aryl hydrocarbon receptor (AHR) is a transcription fac-tor that responds to diverse ligands and plays a critical role in

    E-Print Network [OSTI]

    Bradfield, Christopher A.

    (LBD) bound to 2,3,7,8-tet rachlorodibenzo-p-dioxin (TCDD) and benzo(a)pyrene (BaP) and identified- aling through diverse ligands. Key Words: dioxin; Ah receptor; structural modeling; struc- tural observation that the AHR mediates the toxicity of 2,3,7,8-tet rachlorodibenzo-p-dioxin (TCDD) (Poland et al

  10. A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma

    E-Print Network [OSTI]

    Schnitzbauer, Andreas A.; Zuelke, Carl; Graeb, Christian; Rochon, Justine; Bilbao, Itxarone; Burra, Patrizia; de Jong, Koert P.; Duvoux, Christophe; Kneteman, Norman M.; Adam, Rene; Bechstein, Wolf O.; Becker, Thomas; Beckebaum, Susanne; Chazouilleres, Olivier; Cillo, Umberto; Colledan, Michele; Fandrich, Fred; Gugenheim, Jean; Hauss, Johann P.; Heise, Michael; Hidalgo, Ernest; Jamieson, Neville; Konigsrainer, Alfred; Lamby, Philipp E.; Lerut, Jan P.; Makisalo, Heikki; Margreiter, Raimund; Mazzaferro, Vincenzo; Mutzbauer, Ingrid; Otto, Gerd; Pageaux, Georges-Philippe; Pinna, Antonio D.; Pirenne, Jacques; Rizell, Magnus; Rossi, Giorgio; Rostaing, Lionel; Roy, Andre; Sanchez Turrion, Victor; Schmidt, Jan; Troisi, Roberto I.; van Hoek, Bart; Valente, Umberto; Wolf, Philippe; Wolters, Heiner; Mirza, Darius F.; Scholz, Tim; Steininger, Rudolf; Soderdahl, Gunnar; Strasser, Simone I.; Jauch, Karl-Walter; Neuhaus, Peter; Schlitt, Hans J.; Geissler, Edward K.

    2010-05-11

    is the study statistician. CG, IB, PB, KPdeJ, CD, KK, RA, WOB, TB, SB, OC, UDdiC, MC, FF, JG, JPH, MH, EH, NJ, AK, PEL, JPL, HM, RM, VM, IM, GO, GPP, ADP, JP, MR, GR, LR, AR, VST, JS, RT, BvanH, UV, PW, HHW, DFM, TS, RS, GS, SIS, KWJ, and PN partici- pated... of the Friedrich-Schiller- University, Jena, Germany, 20Scottish Liver Transplant Unit, The Royal Infirmary of Edinburgh, Edinburgh, EH16 4SA, UK, 21Department of Surgery, Addenbrooke's Hospital, Cambridge, UK, 22Department of General-, Visceral...

  11. Identification of novel substrates of the energy-sensing kinase, AMP-activated protein kinase, and regulation of mTOR signaling during energy stress and mitosis

    E-Print Network [OSTI]

    Gwinn, Dana Meredith

    2011-01-01

    and Sinclair, D.A. (2006). Resveratrol improves health andat a High Level on Ser792 Following Resveratrolof the polyphenol compound resveratrol also stimulated acute

  12. Fusion Engineering and Design 80 (2006) 1 ARIES-AT special issue

    E-Print Network [OSTI]

    2006-01-01

    , providing the possibility of high power cycle efficiency; (2) use of high-temperature superconduc- tors

  13. Formalizing Anonymous Blacklisting Systems1 Ryan Henry and Ian Goldberg

    E-Print Network [OSTI]

    Goldberg, Ian

    --Anonymous communications networks, such as Tor, help to solve the real and important problem of enabling users volunteer-run relays called Tor [20], [43]. On an average day, Tor currently helps to protect between 100 is available [23]. through which they route their communications. A typical Tor circuit passes through three

  14. *The contact author is Prof. Yibo Xue (yiboxue@tsinghua.edu.cn). Mr. Chenglong Li is a Ph.Dstudent at Tsinghua University.

    E-Print Network [OSTI]

    Dong, Yingfei

    , Tor 1. INTRODUCTION Tor is the realization of the second generation onion routing for low.Dstudent at Tsinghua University. "Super Nodes" in Tor: Existence and Security Implication ABSTRACT Tor (the second generation onion routing) is arguably the most popular low-latency anonymous communication system now

  15. Multi Path Considerations for Anonymized Routing: Challenges and Opportunities

    E-Print Network [OSTI]

    Yuksel, Murat

    complement underlying onion-routing mechanisms of Tor via exploiting diversity in the Tor network. Our access to the Internet possible for many around the world. Tor network has been built on onion Exit router Onion Proxy Fig. 1. Tor Circuit Establishment user-host creates a TCP connection

  16. Formalizing Anonymous Blacklisting Systems1,2 (Extended Version)

    E-Print Network [OSTI]

    Goldberg, Ian

    ,iang}@cs.uwaterloo.ca Abstract--Anonymous communications networks, such as Tor, help to solve the real and important problem volunteer-run relays called Tor [20], [43]. On an average day, Tor currently helps to protect between 100 they route their communications. A typical Tor circuit passes through three relays; the last relay

  17. Why Johnny Can't Blow the Whistle: Identifying and Reducing Usability

    E-Print Network [OSTI]

    Camp, L. Jean

    ), upwards of 4 million people are connecting to the Tor network daily. Tor uses onion routing [24. The term "onion routing" refers to Tor's layered encryption, analogous to the layers in an onion, which@indiana.edu Abstract--Tor is one of the most widely used anonymity networks in the world. The anonymity provided to any

  18. CIVILIZATION, ROLE OF SOILS D Hillel, Columbia University, New York, NY, USA

    E-Print Network [OSTI]

    of this fragile environment by generations of forest cutters and burners, grazers, cultivators, and irriga- tors

  19. Absence of magnetohydrodynamic activity in the voltage-driven sheet pinch N. Seehafer,1,* E. Zienicke,2

    E-Print Network [OSTI]

    Seehafer, Norbert

    by the Lorentz force. For instance, plasma confinement in tor- oidal devices for controlled thermonuclear fusion

  20. Metal-optic and Plasmonic Semiconductor-based Nanolasers

    E-Print Network [OSTI]

    Lakhani, Amit

    2012-01-01

    of Metals . . . . . . . . . . . . . . . . . . . . . . .coupled Metal-optic Nanocavities . . . . . . . . . . . . . .dependent quality factors Q metal for good conduc- tors.

  1. Parents-tudiants > ASSOCIATION CIGOGNE

    E-Print Network [OSTI]

    Charette, André

    admis dans un programme contingenté. #12;3 0 > RADIO ÉTUDIANTE ­ CISM 89,3 FM Pavillon J.-A.-DeSève 2332, boul. Édouard-Montpetit Local C-1509 Téléphone : 514 343-7511 Télécopieur : 514 343-2418 cism

  2. AREA OVERVIEW----Agent & Data Mining Interaction

    E-Print Network [OSTI]

    Cao, Longbing

    AREA OVERVIEW---- Agent & Data Mining Interaction (ADMI) Longbing Cao Faculty of Information in a Multiple Agent Environment", EWSL91, 1991 Agent-based data mining & knowledge discovery by Davies, W., 1994 Research topics Agent driven data mining Data mining driven agents & multi- agent systems Mutual issues

  3. Jack: Scalable Accumulator-based Nymble System Computer Science & Engineering

    E-Print Network [OSTI]

    Hopper, Nicholas J.

    anonymity provider, Tor [16], is comprised of over 1700 vol- unteer "onion routers" from around the world service pro- viders to block future accesses from abusive users behind anonymizing networks, such as Tor

  4. : An Extensible Platform for Application-Aware Anonymity Micah Sherr

    E-Print Network [OSTI]

    Ives, Zachary G.

    . Similarly, several path instantiation approaches exist. Onion Routing [30] and Tor's telescoping scheme [9 multi-metric perfor- mance constraints as well as existing relay selection algorithms employed by Tor

  5. A. User's Manual B. Sample Coupled Thermal and

    E-Print Network [OSTI]

    Vecchio, Frank J.

    . Vecchio November 2013 #12;VecTor3 Table of Content VecTor3 ............................................................................................................................... i Table of Content....................................................................................... 25 A.2.3.1.1. Defining Node Coordinates

  6. Response to mTOR inhibition: activity of eIF4E predicts sensitivity in cell lines and acquired changes in eIF4E regulation in breast cancer

    E-Print Network [OSTI]

    Satheesha, Sampoorna; Cookson, Victoria J.; Coleman, Louise J.; Ingram, Nicola; Madhok, Brijesh; Hanby, Andrew M.; Suleman, Charlotte A. B.; Sabine, Vicky S.; Macaskill, E. Jane; Bartlett, John M. S.; Dixon, J. Michael; McElwaine, Jim N.; Hughes, Thomas A.

    2011-02-14

    of protein was loaded into wells of 12% NuPAGE bis-tris gels running in MOPS NuPAGE buf- fer (Invitrogen, Paisley, UK). Proteins were transferred to PDVF membrane (Millipore, Billerica, USA) in NuPAGE transfer buffer (Invitrogen, Paisley, UK). Membranes were... DNA was synthesized from oligo-dT primed RNA using Superscript II (Invitrogen, Paisley, UK). Real-time PCR reactions were performed in triplicate using SYBR Green PCR Master Mix on an ABI7900HT machine (Applied Biosystems, Warrington, Satheesha et al. Molecular Cancer...

  7. Optimizing the Placement of Implicit Proxies Jacopo Cesareo

    E-Print Network [OSTI]

    Rexford, Jennifer

    or an anonymizing proxy like TOR (The Onion Router) [5], which in turn directs traffic to the filtered destination

  8. How Did Dread Pirate Roberts Acquire and Protect His Bitcoin Wealth?

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    with the website was carried out through TOR ("The Onion Router"), in order to conceal the true IP addresses

  9. Formalizing Anonymity: A Review University of York Technical Report YCS 389

    E-Print Network [OSTI]

    Stepney, Susan

    .2 Onion Routing . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 4.3 CrowdsMinion) . . . . . . . . . . . . . . . . . . . . . . . . 34 5.5 JAP . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 5.6 Tor

  10. ATP-Competitive Inhibitors of the Mammalian Target of Rapamycin: Design and Synthesis of Highly Potent and Selective Pyrazolopyrimidines

    SciTech Connect (OSTI)

    Zask, Arie; Verheijen, Jeroen C.; Curran, Kevin; Kaplan, Joshua; Richard, David J.; Nowak, Pawel; Malwitz, David J.; Brooijmans, Natasja; Bard, Joel; Svenson, Kristine; Lucas, Judy; Toral-Barza, Lourdes; Zhang, Wei-Guo; Hollander, Irwin; Gibbons, James J.; Abraham, Robert T.; Ayral-Kaloustian, Semiramis; Mansour, Tarek S.; Yu, Ker

    2009-09-18

    The mammalian target of rapamycin (mTOR), a central regulator of growth, survival, and metabolism, is a validated target for cancer therapy. Rapamycin and its analogues, allosteric inhibitors of mTOR, only partially inhibit one mTOR protein complex. ATP-competitive, global inhibitors of mTOR that have the potential for enhanced anticancer efficacy are described. Structural features leading to potency and selectivity were identified and refined leading to compounds with in vivo efficacy in tumor xenograft models.

  11. Optimal Storage Sizing using Two-Stage Stochastic Optimization for Intra-Hourly Dispatch

    E-Print Network [OSTI]

    Li, Xin

    , compressed air, flywheels, double-layer or super/ultra capaci- tors, and batteries (lead-acid, lithium-ion

  12. EDITED BY CAROLINE ASH CREDITS(TOPTOBOTTOM):BURMANNETAL.;MATZELETAL.

    E-Print Network [OSTI]

    Leake, Mark C.

    , such as in regenerative braking in hybrid cars. For very small power requirements, capaci- tors have not been competitive

  13. DISCRETE AND CONTINUOUS Website: www.AIMSciences.org DYNAMICAL SYSTEMS

    E-Print Network [OSTI]

    Díaz, Jesús Ildefonso

    -II Stellara- tor (CIEMAT, Madrid) some evidences have been found about how they improve the confinement [6

  14. ZINC CHLORIDE CATALYSIS IN COAL AND BIOMASS LIQUEFACTION AT PREPYROLYSIS TEMPERATURES

    E-Print Network [OSTI]

    Onu, Christopher O.

    2013-01-01

    ducing the contribution of the nuclear sector to energy sup-contribution of the nuclear sec- tor to overall energy

  15. IEEE TRANSACTIONS ON POWER SYSTEMS, VOL. 16, NO. 3, AUGUST 2001 427 Direct Assessment of Protection Operation and

    E-Print Network [OSTI]

    Hiskens, Ian A.

    and islanding; · voltage dips, which may cause motors to stall, contac- tors to open, and power electronic

  16. Common Data Set 2010-11 CDS-A Page 1

    E-Print Network [OSTI]

    ://admissions.msu.edu/apply/asp Source of institutional control (Check only one): 517-355-8332 517-353-1647 admis@msu.edu 250 categories as of the institution's official fall reporting date or as of October 15, 2010. IncludeCommon Data Set 2010-11 CDS-A Page 1 A0 Respondent Information (Not for Publication) A0 Name: KYLE

  17. Making a Nymbler Nymble using VERBS Ryan Henry, Kevin Henry, and Ian Goldberg

    E-Print Network [OSTI]

    Goldberg, Ian

    Anonymity networks provide users with a means to communicate privately over the Internet. The Tor network to anonymous users (for example, see https://wiki.torproject.org/noreply/TheOnionRouter/BlockingIrc). #12 of existing Tor users, but it might also be a boon to wider acceptance of Tor. Indeed, the need

  18. Page 1 of 807-1226-2439.txt Printed: 12/16/08 Dec 16 4:39:54 PM Printed For: Kate Green

    E-Print Network [OSTI]

    these and related issues, we designed Tor (the onion routing), a widely used low-latency, general-purpose anonymous Project researched, developed, and deployed Tor, the third generation of deployed onion-routing designs Low-Latency Anonymity: Design Challenges and Social Factors by Roger Dingledine (The Tor Project

  19. Private Web Search with Constant Round Efficiency Bolam Kang, Sung Cheol Goh and Myungsun Kim

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    reliable, but complicate systems based on onion rout- ing [19] such as the Tor network [7]. However, the effectiveness of simple solutions is clearly limited. Also, as pointed out by [5] Tor cannot be installed and configured with relative ease. Further, it is well known that the HTTP requests over Tor get significantly

  20. Pisces: Anonymous Communication Using Social Networks Prateek Mittal

    E-Print Network [OSTI]

    Borisov, Nikita

    of deployed anonymity systems such as Tor suffer from two key problems that limit user's trust that leverages users' social links to build circuits for onion routing. We argue that such an approach greatly). Popular anonymity systems include Anony- mizer.com [9], AN.ON [4,16], and Tor [14]. Tor is used

  1. Multi Path Considerations for Anonymized Routing: Challenges and Opportunities

    E-Print Network [OSTI]

    Gunes, Mehmet Hadi

    to the Internet possible for many around the world. Tor network has been built on onion-routing scheme which, Onion-Proxy (OP), which is the Tor software running on end-user computer, connects to a node which can and raising censorship barriers around the world. Tor network has emerged as the most popular option in avail

  2. Using Sphinx to Improve Onion Routing Circuit Construction # Aniket Kate and Ian Goldberg

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    for three onion routing protocols that have emerged as enhancements to the Tor anonymizing network; namely, Tor with predistributed Di#e­Hellman values, pairing­based onion routing, and certificateless onion onion routing project--- Tor [41]---has turned out to be a huge success. However, with its latency times

  3. On the Effectiveness of Low Latency Anonymous Network in the Presence of Timing Attack

    E-Print Network [OSTI]

    Wang, Xinyuan "Frank"

    ], Onion Routing [24], Tor [10], Hordes [28], Web Mixes [6], Tarzan [13]) have been proposed to disguise conducted real-time timing attacks on various deployed anonymous networks such as Tor, anonymizer measurements and timing attack results show that the circuit rotation in Tor network could significantly

  4. Dissent in Numbers: Making Strong Anonymity Scale David Isaac Wolinsky, Henry Corrigan-Gibbs, and Bryan Ford

    E-Print Network [OSTI]

    communication systems make a trade-off between weak anonymity among many nodes, via onion routing, and strong, such as in voting [2,19,44] and auctions [52]. Anonymous relay tools such as Tor [26] offer the strongest practical a user's "first-hop" link to Tor and the "last-hop" link from Tor to the user's communication partner

  5. Leaving timing-channel fingerprints in hidden service log files Bilal Shebaro a,

    E-Print Network [OSTI]

    Crandall, Jedidiah R.

    : Timing channel Fingerprints Tor network Hidden services Timestamps a b s t r a c t Hidden services are anonymously hosted services that can be accessed over an anonymity network, such as Tor. While most hidden based hidden service on the Tor network, where the fingerprint is an additive channel

  6. Post-Quantum Forward-Secure Onion Routing (Future Anonymity in Today's Budget)

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    satrajitgh@gmail.com aniket@mmci.uni-saarland.de Abstract The onion routing (OR) network Tor provides, and it only introduces manageable communication overhead to the Tor protocol. Keywords: Tor, Onion routingPost-Quantum Forward-Secure Onion Routing (Future Anonymity in Today's Budget) Satrajit Ghosh

  7. CS 485/ECE 440/CS 585 Lab 1, Part 1 Due by 11:59pm on Friday, 23 September, as an e-mail to the instructor (jedcrandall@gmail.com).

    E-Print Network [OSTI]

    Crandall, Jedidiah R.

    of the Tor network, specifically the token bucket filter (filters) that is (are) used to limit Tor's bandwidth usage as an onion router. You will be forming a hypothesis, setting up and performing experiments, and then trying to draw some conclusions about why Tor's token bucket filter mechanism(s) may be causing resource

  8. USENIX Association Proceedings of the

    E-Print Network [OSTI]

    Paxson, Vern

    Tor, a circuit-based low-latency anonymous com- munication service. This second-generation Onion not been updated in years. Here we describe Tor, a protocol for asyn- chronous, loosely federated onion encrypted data structure (an onion) to lay each circuit, Tor now uses an incremental or telescoping path

  9. An Analysis of Anonymity Technology Usage Bingdong Li1

    E-Print Network [OSTI]

    Bebis, George

    compared to other systems that incur higher delays. Keywords: Anonymizer, onion routing, Tor 1 Introduction-brewed services through open source anonymous tools. Community contributed systems include The Onion Router (Tor anonymization systems, i.e., anonymous proxy servers, remailers, JAP, I2P and Tor. Among these systems

  10. A policy based approach for the management of Web browser resources to prevent anonymity

    E-Print Network [OSTI]

    Garcia-Alfaro, Joaquin

    when browsing anonymously through the The second generation Onion Router (Tor) network [5 in Tor Guillermo Navarro-Arribas and Joaquin Garcia-Alfaro Abstract Web browsers are becoming through the Tor network is enabled. 1 Introduction The Web is increasingly becoming a universal interface

  11. Stealthy Traffic Analysis of Low-Latency Anonymous Communication Using Throughput Fingerprinting

    E-Print Network [OSTI]

    Singh, Jaswinder Pal

    such as Tor aim to enable users to com- municate in a manner that is untraceable by adversaries that control this leaks in- formation about the set of Tor relays in a circuit (path). We present attacks that, with high the bottleneck relay of any Tor circuit whose throughput can be observed, (b) exactly identify the guard relay

  12. Challenges in deploying low-latency anonymity (DRAFT) Roger Dingledine1

    E-Print Network [OSTI]

    to deploying anonymous communications. Drawing on our experiences deploying Tor (the second-generation onion deploying Tor, a low-latency general-purpose anonymous communi- cation system. We will discuss some discuss some less troublesome open problems that we must nevertheless eventually address. Tor

  13. Proceedings on Privacy Enhancing Technologies 2015 Jamie Hayes and George Danezis

    E-Print Network [OSTI]

    Danezis, George

    for Onion Routing Abstract: "Entry" guards protect the Tor onion rout- ing system from variants strategy would be opti- mal if the Tor network was failure-free and static. How- ever under realistic-05-15. Introduction Tor [DMS04] is one of the most popular low-latency distributed anonymity networks [Cha81

  14. Using Sphinx to Improve Onion Routing Circuit Construction Aniket Kate and Ian Goldberg

    E-Print Network [OSTI]

    Goldberg, Ian

    for three onion routing protocols that have emerged as enhancements to the Tor anonymizing network; namely, Tor with predistributed Diffie-Hellman values, pairing-based onion routing, and certificateless onion onion routing project-- Tor [41]--has turned out to be a huge success. However, with its latency times

  15. TheThe SSuperuper SSecretecret FFileile SSystemystem

    E-Print Network [OSTI]

    Weimer, Westley

    Huang OverviewOverview Implemented CovertFS on top of FUSE Automatic Image Selection from Video Used Tor not like bullets either Image GenerationImage Generation #12;2 Anonymizing with TorAnonymizing with Tor Onion Routing in Action I AM A MEDIA SERVER I

  16. MOR: Monitoring and Measurements through the Onion Router

    E-Print Network [OSTI]

    Markatos, Evangelos P.

    MOR: Monitoring and Measurements through the Onion Router Demetris Antoniades1 , Evangelos P tasks using the geographically diverse infrastructure of the Tor anonymizing network. Through several the infrastructure of #12;the Tor anonymity network [12]. Tor is a free software aiming to protect the privacy of its

  17. TUC: Time-sensitive and Modular Analysis of Anonymous Communication

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    . Our analysis relies on a formalization of the onion routing protocol that underlies Tor and proves@cs.uni-saarland.de mohammadi@cs.uni-saarland.de February 12, 2014 Abstract The anonymous communication protocol Tor constitutes of these frameworks, however, are capable of modeling the class of traffic-related timing attacks against Tor

  18. Annee 2013-2014 1`ere Securite des Syst`emes d'Information

    E-Print Network [OSTI]

    Dorbec, Paul

    `eme discr´etionnaire? 2 The Onion Router TOR (The onion router) est un r´eseau d'anonymisation des.2 (2pt) D'une part, les ´etats h´esitent `a interdire les r´eseaux anonymes tels que TOR, d'autres part´equents utilisateurs. Expliquez. TOR utilise le protocole suivant (ici simplifi´e): 1. L'´emetteur S utilise une liste

  19. EROSION-CORROSION-WEAR PROGRAM

    E-Print Network [OSTI]

    Levy, Alan V.

    2013-01-01

    presence of char in coal gasification reac- tors provides aand operation of coal gasification systems, coal fireddifferent gasification processes and starting coals. i·Brief

  20. Buildings and Energy in the 1980's (TABLES)

    U.S. Energy Information Administration (EIA) Indexed Site

    in Residential Buildings, 1984 End Uses RSE Row Fac- tors All End Uses Space Heating Water Heating Air Conditioning Appliances Building Characteristics Buildings (thou- sand)...

  1. Buildings and Energy in the 1980's (TABLES)

    U.S. Energy Information Administration (EIA) Indexed Site

    in Residential Buildings, 1987 End Uses RSE Row Fac- tors All End Uses Space Heating Water Heating Air Conditioning Appliances Building Characteristics Buildings (thou- sand)...

  2. Buildings and Energy in the 1980's (TABLES)

    U.S. Energy Information Administration (EIA) Indexed Site

    1982 End Uses RSE Row Fac- tors All End Uses Space Heating Water Heating Air Conditioning Appliances Building Characteristics Buildings (thou- sand) Consump- tion...

  3. Buildings and Energy in the 1980's (TABLES)

    U.S. Energy Information Administration (EIA) Indexed Site

    1980 End Uses RSE Row Fac- tors All End Uses Space Heating Water Heating Air Conditioning Appliances Building Characteristics Buildings (thou- sand) Consump- tion...

  4. Buildings and Energy in the 1980's (TABLES)

    U.S. Energy Information Administration (EIA) Indexed Site

    1981 End Uses RSE Row Fac- tors All End Uses Space Heating Water Heating Air Conditioning Appliances Building Characteristics Buildings (thou- sand) Consump- tion...

  5. Boundary shape identification in twodimensional electrostatic problems using SQUIDs

    E-Print Network [OSTI]

    of conduc­ tors using superconducting quantum interference devices ( SQUIDs ). A measurement system. SQUIDs ( superconducting quantum interference devices ) have the potential to detect material defects

  6. Exascale for Energy: The Role of Exascale Computing in Energy Security

    E-Print Network [OSTI]

    Authors, Various

    2010-01-01

    GNEP). These advanced burner reac- tors (ABRs) are expectedtransition. Lean premixed burners are one example of a newTheoretically these burners could operate cleanly and

  7. Modeling Light Propagation in Luminescent Media

    E-Print Network [OSTI]

    Sahin, Derya

    2014-01-01

    conditions . . . . . . . 3.1.3 Solar-averaged opticaland B. P. Wittmershaus, Solar Energy 83, 566 (2009). [39] G.transport in luminescent solar concentra- tors based on

  8. High Resolution Additive Patterning of Nanoparticles and Polymers Enabled by Vapor Permeable Polymer Templates

    E-Print Network [OSTI]

    Demko, Michael Thomas

    2012-01-01

    conduc- tors for flexible electronics. Journal of theelectrodes on flexible electronics. 7,91 When nanoparticleNanoscale patterning and electronics on flexible sub- strate

  9. Impacts of seasonal and regional variability in biogenic VOC emissions on surface ozone in the Pearl River delta region, China

    E-Print Network [OSTI]

    2013-01-01

    chained carbonyl compounds from Eucalyptus spp. in southernby changing all forest to eucalyptus, except for protectedlocal natural parks. The eucalyptus BVOC emission fac- tors

  10. A, E.K.Ris Ris-M-OHj Title and authors)

    E-Print Network [OSTI]

    or group Department of fee-«'tor Technology Group's own registration numbers) RT-^-*5 Abstract The work seven of the Department'a graduate

  11. spectrum30m.eps

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Yipeng Sun SLAC National Accelerator Laboratory, Menlo Park, California 94025, USA Paul Emma, Tor Raubenheimer and Juhao Wu SLAC National Accelerator Laboratory, Menlo...

  12. Alternative approaches to eradicating the malignant clone in chronic myeloid leukemia: tyrosine-kinase inhibitor combinations and beyond.

    E-Print Network [OSTI]

    Ahmed, Wesam; Van Etten, Richard A

    2013-01-01

    G, Fenouille N, et al. Resveratrol promotes autophagic cellChloroquine Panobinostat Resveratrol, SRT501 Sabutoclax62 Stimulation of AMPK by resveratrol inhibits mTOR and has

  13. www.kit.edu RESEARCH TO BUSINESS

    E-Print Network [OSTI]

    Stein, Oliver

    : Energieumwandlung, Erneuerbare Energien, Energiespei- cherung und -verteilung, Effiziente Energienutzung- tor ermöglicht hochempfindliche Detektion Seite 7 Kunden-Newsletter Innovation Ausgabe 2|2008 Energien

  14. Derived Hom-Tensor adjointness. Local duality.

    E-Print Network [OSTI]

    2009-02-22

    Feb 16, 2009 ... 1 Left-derived functors. Tensor and Tor. 2 Hom -Tensor adjunction. 3 Abstract local duality. 4 Concrete local duality. 5 Residues and duality for ...

  15. Brain-derived neurotrophic factor promotes long-term potentiation-related cytoskeletal changes in adult hippocampus.

    E-Print Network [OSTI]

    Rex, Christopher S; Lin, Ching-Yi; Kramár, Eniko A; Chen, Lulu Y; Gall, Christine M; Lynch, Gary

    2007-01-01

    RC, Nicoll RA (1998) Brain-derived neurotrophic fac- tor (term potentiation by brain-derived neurotrophic factor. JSystems/Cognitive Brain-Derived Neurotrophic Factor Promotes

  16. AMPA receptor-induced local brain-derived neurotrophic factor signaling mediates motor recovery after stroke.

    E-Print Network [OSTI]

    Clarkson, Andrew N; Overman, Justine J; Zhong, Sheng; Mueller, Rudolf; Lynch, Gary; Carmichael, S Thomas

    2011-01-01

    polymorphism in the brain-derived neurotrophic factor gene (Chronic elevation of brain-derived neurotrophic factor bysustained increases in brain-derived neurotrophic fac- tor

  17. Scalable Onion Routing with Torsk Jon McLachlan

    E-Print Network [OSTI]

    Hopper, Nicholas J.

    Scalable Onion Routing with Torsk Jon McLachlan University of Minnesota Minneapolis, MN 55455 mcla service of the popular Tor anonymity network, that decreases the bandwidth cost of relay selection and maintenance from quadratic to quasilinear while introducing no new attacks on the anonymity provided by Tor

  18. Efficient Unobservable Anonymous Reporting against Strong Adversaries

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    not provided by existing systems and practical designs, e.g., Tor), specifically: - Provable unobservability, together with an anonymization module, which can use either Onion- Routing (DURPOR ) or Crowds (DURPCrowds to weak anonymity (and high efficiency) decentralized designs, e.g., Tor [1], the most well known

  19. Using Sphinx to Improve Onion Routing Circuit Construction (short paper)

    E-Print Network [OSTI]

    Goldberg, Ian

    for three onion routing protocols that have emerged as enhancements to the Tor anonymizing network; namely, Tor with predistributed Diffie- Hellman values, pairing-based onion routing, and certificateless onionUsing Sphinx to Improve Onion Routing Circuit Construction (short paper) Aniket Kate and Ian

  20. Onion Routing Circuit Construction Via Latency Graphs Sergio Castillo-Perez,a

    E-Print Network [OSTI]

    Garcia-Alfaro, Joaquin

    privacy problems on the Internet. Tor (short for The onion router) is a popular low-latency anonymity]. Nowadays, it is distributed as a free software implementation known as Tor (The onion router [2]). It canOnion Routing Circuit Construction Via Latency Graphs Sergio Castillo-P´erez,a , Joaquin Garcia

  1. Forensic Investigation of the OneSwarm Anonymous Filesharing System

    E-Print Network [OSTI]

    Massachusetts at Amherst, University of

    different method than Onion Routing (OR), which is the architectural basis for Tor [6]. If a peer possesses to provide Onion Routing-like privacy and BitTorrent-like performance. We demonstrate several flaws in OneSwarm's design and implementation through three different attacks available to forensic investiga- tors. First

  2. Seeking Anonymity in an Internet Panopticon Joan Feigenbaum and Bryan Ford

    E-Print Network [OSTI]

    Ford, Bryan

    is chal- lenging, however. The state of the art in deployed tools, such as Tor [1], uses onion routing (OR in principle de-anonymize many Tor users in a matter of days [14]. Through intersection attacks, an adversary work analyzes onion routing [10], but relies on idealized formal models making assumptions

  3. Probabilistic Analysis of Onion Routing in a Black-box Model JOAN FEIGENBAUM, Yale University

    E-Print Network [OSTI]

    , Tor 1. INTRODUCTION Every day, half a million people use the onion-routing network Tor [Dingledine etA Probabilistic Analysis of Onion Routing in a Black-box Model JOAN FEIGENBAUM, Yale University a probabilistic analysis of onion routing. The analysis is presented in a black-box model of anonymous

  4. Provably Secure and Practical Onion Routing Michael Backes

    E-Print Network [OSTI]

    Goldberg, Ian

    Saarbr¨ucken, Germany mohammadi@cs.uni-saarland.de Abstract--The onion routing network Tor is undoubtedly. INTRODUCTION Over the last few years the onion routing (OR) network Tor [28] has emerged as a successfulProvably Secure and Practical Onion Routing Michael Backes Saarland University and MPI-SWS Saarbr

  5. Probabilistic Analysis of Onion Routing in a Black-box [Extended Abstract

    E-Print Network [OSTI]

    --Distributed applications General Terms Algorithms, Security, Theory Keywords Anonymity, onion routing, Tor A full version-1-59593-883-1/07/0010 ...$5.00. 1. INTRODUCTION Every day, thousands of people use the onion-routing net- work Tor [6Probabilistic Analysis of Onion Routing in a Black-box Model [Extended Abstract] Joan Feigenbaum

  6. Towards Efficient Traffic-analysis Resistant Anonymity Networks Stevens Le Blond1

    E-Print Network [OSTI]

    Druschel, Peter

    Mixminion batch messages to re- sist traffic-analysis at the expense of low latency. Onion routing schemes like Tor deliver low latency and high band- width, but are not designed to withstand traffic analysis complied with a US subpoena to trace one of its users [1]. Network anonymization services like Tor provide

  7. Hiding Amongst the Clouds: A Proposal for Cloud-based Onion Routing Nicholas Jones, Matvey Arye, Jacopo Cesareo, and Michael J. Freedman

    E-Print Network [OSTI]

    Singh, Jaswinder Pal

    number of volunteers (as Tor does), we propose mov- ing onion-routing services to the "cloud" to leverageHiding Amongst the Clouds: A Proposal for Cloud-based Onion Routing Nicholas Jones, Matvey Arye and surveillance have made anonymity tools increasingly critical for free and open Internet access. Tor, and its

  8. Provably Secure and Practical Onion Routing Michael Backes

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    @cs.uni-saarland.de Abstract The onion routing network Tor is undoubtedly the most widely employed technology for anony- mous and Predictable Malleability . . . . . . . . . . . . . . . . . . 22 6.2 Security of Tor's Onion AlgorithmsProvably Secure and Practical Onion Routing Michael Backes Saarland University and MPI-SWS, Germany

  9. LIRA: Lightweight Incentivized Routing for Rob Jansen Aaron Johnson

    E-Print Network [OSTI]

    servicing the network. I. INTRODUCTION Onion routing [1], particularly as deployed in Tor [2], [3 Laboratory {rob.g.jansen, aaron.m.johnson, paul.syverson}@nrl.navy.mil Paul Syverson Abstract--Tor, the most popular deployed distributed onion routing network, suffers from performance and scalability prob- lems

  10. Onions for Sale: Putting Privacy on the Market Aaron Johnson, Rob Jansen, and Paul Syverson

    E-Print Network [OSTI]

    Johnson, Aaron

    Overview Onion routing, and in particular the Tor network, is tech- nically well-designed to provideD RA FT Onions for Sale: Putting Privacy on the Market Aaron Johnson, Rob Jansen, and Paul Syverson source of trust. Proposed Solution We propose that Tor supports the optional purchase of its services

  11. Preventing Active Timing Attacks in Low-Latency Anonymous Communication

    E-Print Network [OSTI]

    Johnson, Aaron

    elsewhere, and it can be quite insufficient. Consider Tor [7], the popular imple- mentation of onion. Low-latency anonymous communication protocols in gen- eral, and the popular onion-routing protocol on the Tor network to estimate the real-world per- formance of our protocol, showing that the added delay

  12. Anonym activities: white-and blackhat applications

    E-Print Network [OSTI]

    Jelasity, Márk

    techniques Tor ­ basic idea of onion routing ­ current status and some problems #12;5 Storm Botnet appeared) #12;16 Tor Can provide anonymity for both clients and servers (the latter using the ".onion" domain) So called "onion" routing Originally funded by US Naval Research Lab ­ To provi

  13. Project Icarus: Astronomical Considerations Relang to the Choice of Target Star 1. INTRODUCTION

    E-Print Network [OSTI]

    Crawford, Ian

    R) docu- ment [1]. The most relevant ToR relating to the selection of the target star(s) are: ToR#3: "The, these imply a maximum realistic range of about 15 light-years from the Solar System. This would imply by Webb [5] and Crawford [6], and for Icarus specifically as a trade study conducted within Icarus Module

  14. University , miniconference

    E-Print Network [OSTI]

    Zakharov, Leonid E.

    ,exp Local Troyon #12;N (r): #12;N (r) #17; 2#22; 0 ( p)j r B 2 tor rB tor I pl (r) Green points wisdom: Plasma boundary provides boundary conditions for internal transport source Energy External heating Plasma walls Conventional ENERGY FLUX : convection TERMO­CONDUCTION Particle outflux Wall particle

  15. ZONAL PRICING AND DEMAND-SIDE BIDDING IN THE NORWEGIAN ELECTRICITY MARKET

    E-Print Network [OSTI]

    California at Berkeley. University of

    .3 Retail Markets 9 2.4 Generating Plants 10 2.5 Storage, Generation, Price and Trade Patterns 14 3. SupplyPWP-063 ZONAL PRICING AND DEMAND-SIDE BIDDING IN THE NORWEGIAN ELECTRICITY MARKET Tor Arnt Johnsen.ucei.berkeley.edu/ucei #12;ZONAL PRICING AND DEMAND-SIDE BIDDING IN THE NORWEGIAN ELECTRICITY MARKET Tor Arnt Johnsen, Shashi

  16. Protein Degradative Processes Associated with Anabolic Dysregulation in Diabetic Skeletal Muscle 

    E-Print Network [OSTI]

    Perticone, Jacqueline Ilene

    2014-05-19

    TOR)-interacting protein (DEPTOR), a potent negative binding partner of mTOR, is reduced in skeletal muscle of diabetic rats, suggesting that regulation of this protein may participate in the altered protein metabolism. The purpose of this investigation was to assess key...

  17. FUJIMORI ET AL. VOL. 7 ' NO. 6 ' 56075613 ' 2013 www.acsnano.org

    E-Print Network [OSTI]

    Tománek, David

    exploited in applications ranging from solar cells, light-switching devices, and rectifiers to xerographic that show topological insula- tor behavior,10À12 CdSe nanocrystals form- ing quantum dots,13 and cubane

  18. Microsoft Word - 2005 Smooth Brome 032206 FINAL.doc

    Office of Environmental Management (EM)

    n i c a D ra w So uth Int erc ep tor Di tch W o m a n C re ek Smooth Brome Treatment Location Smooth Brome Weed Control Locations Figure 2 DATA SOURCE BASE FEATURES: Buildings,...

  19. Buildings and Energy in the 1980's

    U.S. Energy Information Administration (EIA) Indexed Site

    Table R8.82p. Total and Average Primaary Consumption and Expenditures for All Major Energy Sources in Residential Buildings, 1982 Total Average RSE Row Fac- tors Expenditures...

  20. Buildings and Energy in the 1980's

    U.S. Energy Information Administration (EIA) Indexed Site

    Table R8.90p. Total and Average Primary Consumption and Expenditures for All Major Energy Sources in Residential Buildings, 1990 Total Average RSE Row Fac- tors Expenditures...

  1. Buildings and Energy in the 1980's

    U.S. Energy Information Administration (EIA) Indexed Site

    Table R8.81p. Total and Average Primary Consumption and Expenditures for All Major Energy Sources in Residential Buildings, 1981 Total Average RSE Row Fac- tors Expenditures...

  2. Buildings and Energy in the 1980's

    U.S. Energy Information Administration (EIA) Indexed Site

    Table R8.84p. Total and Average Primary Consumption and Expenditures for All Major Energy Sources in Residential Buildings, 1984 Total Average RSE Row Fac- tors Expenditures...

  3. Small Molecule Target Identification using Drug Affinity Responsive Target Stability (DARTS)

    E-Print Network [OSTI]

    Lomenick, Brett Eugene

    2013-01-01

    vehicle control, or with celecoxib (Panacea Biotec Ltd. ,mTOR-rapamycin, COX-2–celecoxib, and Smer3-Met30 (8) (Figuredidemnin B with eEF1A, celecoxib with COX-2, and Smer3 with

  4. Towards Instance Query Answering for Concepts Relaxed by Similarity Measures Andreas Ecke

    E-Print Network [OSTI]

    Baader, Franz

    `cfAED' Partially supported by DFG in the Collaborative Research Cen- ter 912 "Highly Adaptive Energy-Efficient. A particular DL is characterized by a set of concept construc- tors, which allow to build complex concept

  5. Low-Voltage Switched-Capacitor Circuits Emad Bidari

    E-Print Network [OSTI]

    Moon, Un-Ku

    Low-Voltage Switched-Capacitor Circuits by Emad Bidari A THESIS submitted to Oregon State . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 2. THE OPERATION AND IMPLEMENTATION OF THE LOW-VOLTAGE INTEGRA- TOR. LOW-VOLTAGE SC FILTER STAGES

  6. Form 836 (7/06) Approved for public release;

    E-Print Network [OSTI]

    Salisbury, Kenneth

    OpenCL , unstructured grids, more operato tline ion and analysis operations onion and analysis operations on ers ming and the Thrust library tors ormance e machinese machines ors ParaView integration

  7. CM157A-04 ACM-TRANSACTION August 9, 2003 14:41 Behavior of the NORTA Method for

    E-Print Network [OSTI]

    Henderson, Shane

    University The NORTA method is a fast general-purpose method for generating samples of a random vec- tor, semidefinite programming, sampling random matrices, onion method 1. INTRODUCTION In many settings

  8. pintronics devices [1] made from metallic thin films have already been successful for a decade.

    E-Print Network [OSTI]

    Grundler, Dirk

    interest in spin excitations in nanostructured solids. For semiconduc- tor solids a major driving source) Ferromagnetic resonance of the Ni80Fe20 refer- ence film at 90 mT. Sketches in (d) and (e) com- pare the onion

  9. Schedule of Classes Spring 2011

    E-Print Network [OSTI]

    Quarter, facilita- tors work closely with their faculty sponsors through a two-unit independent study, and The Onion: When Nonsense Makes Sense Michelle Mikolajczyk Reed Wilson English 88SC Not Gay--Just a Fairy

  10. Insects of the Garden, With a Chapter on the Melon Louse and Other Aphids. 

    E-Print Network [OSTI]

    Conradi, Albert F. (Albert Frederick); Sanborn, C. E.

    1906-01-01

    Cle MISS M. H. WATKINS ........................................ 1 . Stenograp? tor :or rol ~t-k ,A ier STATE SUB-STATIONS S. A. WASCHKA, superintendent ........... .................. Trou p Smith County W. S. HOTCHKISS, Superintendent... .......... ........ ... ............................................................................................................ 18 Squash .............................................................................................................................. .......................... 18 Onion...

  11. Bounds on the leakage of the input's distribution in information-hiding protocols

    E-Print Network [OSTI]

    Palamidessi, Catuscia

    and the observables. This is the case, for example, of many anonymity protocols, such as Crowds [22], Onion Routing [27], Tor [13], Tarzan [14], Mix-Nets [7], DC Nets [6], etc. A common framework for studying

  12. Privacy-preserving Queries over Relational Databases

    E-Print Network [OSTI]

    Goldberg, Ian

    techniques, such as onion routers and mix networks, offer anonymizing protection for users' identities the query through Tor [12] to preserve the privacy of his or her network address. Nevertheless, the server

  13. WHISPER: Middleware for Confidential Communication in Large-Scale Networks

    E-Print Network [OSTI]

    Rivière, Etienne

    of the members of the group, must be provided by anonymizing systems such as TOR [1]. These systems rely on a set of dedicated servers that conceal the source of the message from the destination, typically using onion rout

  14. Privacy-preserving Queries over Relational Databases Femi Olumofin

    E-Print Network [OSTI]

    Goldberg, Ian

    . While today's most developed and deployed privacy tech- niques, such as onion routers and mix networks' queries. For the front running example, the user could tunnel the query through Tor [17] to preserve

  15. Sensorentwicklung fur Turbulenzmessungen Michael Holling

    E-Print Network [OSTI]

    Peinke, Joachim

    Detektierung von Verbiegung und Tor- sion des Cantilevers erm¨oglicht. Auf Basis dieser Daten wurde eine¨omwinkel erm¨oglicht und damit ebenfalls der longitudinalen und trans- versalen Geschwindigkeitskomponente der

  16. on the tempered spectrum of quasi-split classical groups

    E-Print Network [OSTI]

    of M. In order to do this, we study the poles of the standard intertwining opera- tors that arise ...... Since we are assuming that z' is self-dual, ...... 1101-1151.

  17. 1314 MRS BULLETIN VOLUME 37 DECEMBER 2012 www.mrs.org/bulletin 2012 Materials Research Society While working at the Molecular Physics Laboratory at SRI

    E-Print Network [OSTI]

    for electrical energy storage in ultracapaci- tors and batteries; conductive thin films; barrier films; and many happened when the pillars were rubbed with a piece of silicon wafer, as observed by scanning electron

  18. Environmental Health Perspectives volume 121 | number 3 | March 2013 359 Emerging evidence supports the idea that

    E-Print Network [OSTI]

    Blumberg, Bruce

    balance between energy intake and energy expenditure; however, additional fac- tors are important and Blumberg 2011). Obesity has become a burgeoning epidemic in the developed world over the past 30 years

  19. PLEASE RUSH

    Office of Legacy Management (LM)

    washers out of U v Beta metal slab on punch press. Re No ventilation in area. Oil pH pira tor worn. 1816 1433 BZ Same as 1815 - 32 washers stamp- .02 3 .06 ed in this...

  20. Internalizing Climate Change—Scientific Resource Management and the Climate Change Challenges

    E-Print Network [OSTI]

    Dettinger, Michael D.; Culberson, Steven

    2008-01-01

    Council. 2001. Climate change sci- ence: an analysis of someM, Miller HL, edi- tors. Climate Change 2007: The PhysicalIntergovernmental Panel on Climate Change(IPCC)]. Cambridge,

  1. COMBINING PROOFS AND PROGRAMS Chris Casinghino

    E-Print Network [OSTI]

    Weirich, Stephanie

    the specifics of a language design in the context of multi-day research meetings with 15-20 collabora- tors. I but helpful and have demonstrated a repeated commitment to the success of everyone in the group (especially

  2. Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive

    E-Print Network [OSTI]

    Lamming, Dudley W.

    Rapamycin, an inhibitor of the mechanistic target of rapamycin (mTOR) signaling pathway, extends the life span of yeast, worms, flies, and mice. Interventions that promote longevity are often correlated with increased ...

  3. 3D Spectroscopic Instrumentation Matthew A. Bershady

    E-Print Network [OSTI]

    Bershady, Matthew A.

    .1.1 The Detector Limit-I: Six into Two Dimensions Astronomical data exist within 6-dimensional hyper-cube sampling polarizations. In contrast, high-efficiency, panoramic digital detec- tors today are only two-dimensional (with

  4. Efficiently Matching Sets of Features with Random Histograms

    E-Print Network [OSTI]

    Makarychev, Konstantin

    advanced search systems for audio [23], video [29] and sensor data also use sets of unordered high-dimensional feature vec- tors as their metadata representations, thus it is important to develop a flexible, effective

  5. NEWBORN'S BIOMETRIC IDENTIFICATION: CAN IT BE DONE? Daniel Weingaertner, Olga Regina Pereira Bellon and Luciano Silva

    E-Print Network [OSTI]

    ,olga,luciano}@inf.ufpr.br M^onica Nunes Lima Cat Department of Pediatrics, Universidade Federal do Paran´a, Curitiba, Brasil doc- tors, nurses and police officers. We are also grateful for the parents that gave their consent

  6. Effects of specimen thickness and impurity on the conductivity of alumina under electron irradiation

    E-Print Network [OSTI]

    Howlader, Matiar R

    windows in the International Thermonuclear Experimental Reactor (ITER), where the electrical conductivity believed to be critical issues for the application of a-Al2O3 to insulators in fusion reac- tors. The RIC

  7. AN ARCHITECTURE FOR DISTRIBUTED VISUAL MEMORY Nils Jungclaus, Markus von der Heyde, Helge Ritter, Gerhard Sagerer

    E-Print Network [OSTI]

    ) 360, Situated Artificial Communica- tors, where a hybrid vision system combining neural and semantic variability of sensory signals ­ be they natural or artificial ­ into more stable entities that correlate

  8. Introduction If any culture area appears well suited for the

    E-Print Network [OSTI]

    Kemp, Brian M.

    such as the US Southwest, US Southeast, Mesoamerica, Africa, and Asia (e.g., Banning 1996; Ciolek-Tor- rello1996 absolute dating methods. Second, I examine temporality in relation to the architecture of the house itself

  9. The first occurrence of the neurotoxin domoic acid (DA) in Humboldt squid (Dosidicus gigas) during a toxic

    E-Print Network [OSTI]

    . gigas have taken place both historically and recently along the Eastern Pacific rim content analysis indicated that possible DA vec- tors to Humboldt squid included both pelagic (Pacific hake, Merluccius productus, and Pacific sardine, Sardinops sagax) and nearshore (pile surfperch

  10. www.sciencesignaling.org/cgi/content/full/4/196/rs10/DC1 Supplementary Materials for

    E-Print Network [OSTI]

    Perrimon, Norbert

    10628 barr Kary3 Grp1 Cka InR CG31704 PTEN CG8291 CG3173 CG15615 SerT gig (Tsc2) fliI Tor CG10955 S6K

  11. Heteroepitaxial Decoration of Ag Nanoparticles on Si Nanowires: A Case Study

    E-Print Network [OSTI]

    Xiong, Qihua

    , due to their potential applications in solar energy conversion,15 surface-enhanced Raman scattering the following equations where M denotes metal atoms (e.g., Au or Pt). Semiconduc- tors, for example, silicon

  12. Challenges on Low-Power Platform Design for Real-World Wireless Sensing Applications

    E-Print Network [OSTI]

    Shinozuka, Masanobu

    batteries, solar panels, and energy storage. The platform as a whole will operate even more efficiently and mechanical systems. The purpose is to moni- tor and assess the structural integrity of buildings, airplanes

  13. 30TH INTERNATIONAL COSMIC RAY CONFERENCE The PAMELA Electromagnetic Calorimeter: Flight Status

    E-Print Network [OSTI]

    Morselli, Aldo

    is surrounded by a plas- tic scintillator veto shield (AC). An electromag- netic calorimeter mounted below detection system (ND) comprising 3 He­filled tubes within a polyethylene modera- tor for the selection

  14. Anomalous electron-ion energy coupling in electron drift wave turbulence

    E-Print Network [OSTI]

    Zhao, Lei

    transport: new aspects for nuclear fusion reac- tor design,BRAAMS and P.E. STOTT, Nuclear Fusion: Half a Century ofto know something about nuclear fusion. Everything happened

  15. Pyrite oxidation in saturated and Unsaturated Porous Media Flow: A Comparison of alternative mathematical modeling approaches

    E-Print Network [OSTI]

    Xu, Tianfu; White, Stephen P.; Pruess, Karsten

    2008-01-01

    is the primary source of acid drainage from mines and waste1981, Biogeochemistry of acid mine drainage and a method toR. , 1995, Modeling Acid Mine Drainage in Waste Rock Dumps,

  16. IDENTIFICATION AND CONVEXITY IN OPTIMIZING CONTROL Bjarne A. Foss

    E-Print Network [OSTI]

    Foss, Bjarne A.

    Cybernetics, Norwegian University of Science and Technology, N-7034 Trondheim, Norway. Email: baf@itk.unit.no Tor A. Johansen SINTEF Electronics and Cybernetics, Automatic Control Department, N-7034 Trondheim

  17. System-Level Characterization of Single-Chip Radios

    E-Print Network [OSTI]

    for wireless sensor network nodes. I. INTRODUCTION The two factors that dominate wireless sensor network (WSN observed by many WSN investiga- tors at the LLC or MAC level [1], [2], [3], [4]; there is a large gap

  18. Aminoglycoside antibiotics inhibit protein biosynthesis and various ribozymes. Structural electrostatic

    E-Print Network [OSTI]

    Westhof, Eric

    Descartes, F-67084 Strasbourg, France. Correspondence: Yitzhak Tor and Eric Westhof E-mail: ytor to aminoglycoside binding [25]; and, importantly, the crystal structures of two hammer- head ribozymes have been

  19. In Vitro Evaluation of Multiobjective Hemodynamic Control of a Heart-Assist Pump

    E-Print Network [OSTI]

    Paden, Brad

    the need for flow sensors, a state estima- tor was used, based on the back-EMF of the actuator proximity of suction but without actually achieving suction. In the absence of sensors to directly detect

  20. Geological challenges in radioactive waste isolation: Third worldwide review

    E-Print Network [OSTI]

    Witherspoon editor, P.A.; Bodvarsson editor, G.S.

    2001-01-01

    in commercial operation (Atucha I and Embalse) and oneresearch reac- tor (RA3). The Atucha I nuclear power plant (uranium (LEU). At the Atucha I NPP, spent fuel containing

  1. The Cryosphere, 8, 607621, 2014 www.the-cryosphere.net/8/607/2014/

    E-Print Network [OSTI]

    Moore, John

    in simulations despite varying enhancement fac- tor, geothermal heat flux and surface temperatures over large, UK 5College of Global Change and Earth System Science, Beijing Normal University, Beijing, China 6

  2. Aharonov-Casher and spin Hall effects in mesoscopic ring structures with strong spin-orbit interaction RID A-1315-2011 RID B-3617-2008 

    E-Print Network [OSTI]

    Borunda, M. F.; Liu, Xin; Kovalev, Alexey A.; Liu, Xiong-Jun; Jungwirth, T.; Sinova, Jairo.

    2008-01-01

    - conductor systems. B. Spin Hall effect The proposal of intrinsic spin Hall effect37 and the experi- mental observation of the effect ?both extrinsic and intrinsic?38 has generated a lot of interest in the semiconduc- tor spintronics community. Numerical...

  3. THE C*-ALGEBRA OF A VECTOR BUNDLE 1. Introduction Let E ...

    E-Print Network [OSTI]

    2010-07-19

    Jul 19, 2010 ... to the Doplicher-Roberts algebra of ?(E), see [7]. Let us recall that if E is .... that m and ?d/2?! are relatively prime and that Tor(H?(X,Z),Z/m) = 0.

  4. Tenure Track-Professorinnen und -Professoren der TUM (berufen seit April 2012): Name Professur Vorherige Institutionen

    E-Print Network [OSTI]

    Cengarle, María Victoria

    of Energy Conversion Ruhr-Universität Bochum (D) / and Storage Technical University of Denmark (DK) Matthias) / and Risk Management in Energy Markets Universität Wien (AUT) #12; University (USA) Alessio Gagliardi Simulation of Nanosystems for Energy Università Roma Tor Vergata (I

  5. Low Latency High Bandwidth Anonymous Overlay Network with Anonymous Routing

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    [3,4,10,7,6,16,14,8,11]. Most of these networks are based on one of two methods: onion routing and DC to be re-configured). Research into the per- formance of Tor [6] and JAP [14] shows a high latency (e.g. around 4 seconds for some Cascades in JAP, around 4.5 seconds for Tor) and either a low (e.g. around 15

  6. Rev: The fire is in the fat

    E-Print Network [OSTI]

    Armitage, Kenneth

    1984-01-01

    through 1982. In the introductory chapter, the edi­ tors attempt to sort out some of the terminological tangle resulting from two different approaches: that of the whole- animal nutritionist concerned with ener­ gy budgets and of the cellular bioenerge... through 1982. In the introductory chapter, the edi­ tors attempt to sort out some of the terminological tangle resulting from two different approaches: that of the whole- animal nutritionist concerned with ener­ gy budgets and of the cellular bioenerge...

  7. Covert Communication Networks 

    E-Print Network [OSTI]

    Nix, Timothy Glen

    2013-08-02

    using shared keys assigned by the blender when a new jondo joins the crowd. Tor is the most popular anonymous communications system in use and is known as the second-generation onion router due to the fact that it is based on, and makes several modi... cations to the original onion routing design in terms of security, e - ciency, and deployability [17]. Tor uses a small set of trusted directory servers in order to distribute information about known onion routers in the network. In order to create a...

  8. Factored Language Models and Generalized Parallel Backoff Jeff A. Bilmes Katrin Kirchhoff

    E-Print Network [OSTI]

    Washington at Seattle, University of

    model, a word is viewed as a vec- tor of k factors, so that wt {f1 t , f2 t , . . . , fK t }. Fac- tors. An FLM is a model over factors, i.e., p(f1:K t |f1:K t-1:t-n), that can be factored as a product of probabilities of the form p(f|f1, f2, . . . , fN ). Our task is twofold: 1) find an appropriate set of factors

  9. Low sidewall damage plasma etching using ICP-RIE with HBr chemistry of Si=SiGe

    E-Print Network [OSTI]

    beyond the expected limitation forecasted by the International Technology Roadmap for Semiconduc- tors:1:100). The combination of HBr process gas and very low substrate bias power (10 W) for inductively coupled plasma- junction bipolar transistors (HBT) make Si-based RITDs excellent candidates to extend the Si technology

  10. Optimal Power Train Design of a Hybrid Refuse Collector Vehicle

    E-Print Network [OSTI]

    Noé, Reinhold

    components like an electrical machine, an energy storage, etc. In order to exploit full potential is possible with most of hybrid electric vehicles, promises significant fuel saving. In addition. Apart from fuel savings, an electrically powered collec- tor unit allows noise reduction

  11. PASSIVITY BASED NONLINEAR CONTROL OF HYDRAULIC ACTUATORS BASED ON AN EULER-LAGRANGE FORMULATION

    E-Print Network [OSTI]

    Li, Perry Y.

    for this energy function. A passiv- ity property for the actuator is exhibited in which the hydraulic supply rate- work for the mechanical-pressure dynamics in a hydraulic actua- #12;tor based upon physical energyPASSIVITY BASED NONLINEAR CONTROL OF HYDRAULIC ACTUATORS BASED ON AN EULER-LAGRANGE FORMULATION

  12. AOML is an environmental laboratory of NOAA's Office of Oceanic and Atmospheric Research on Virginia Key in Miami, Florida January-February 2012

    E-Print Network [OSTI]

    to assessing the tropical ocean current system partly responsible for the fresh water budget. AOML will alsoAOML is an environmental laboratory of NOAA's Office of Oceanic and Atmospheric Research Administra- tor of NOAA's Office of Oceanic and Atmo- spheric Research in January and began his new duties

  13. Variation of adsorption geometries by the influence of nucleophilicity among p-CPA, p-TPA, and p-NPA on Ge(100)

    E-Print Network [OSTI]

    Kim, Sehun

    molecules except for amino acid yet. Based on the results from the previous research into adsorption of multifunctional molecules such as amino acids on semiconduc- tor surface is an useful and interesting topic configuration of various amino acids, we examined the adsorption of other molecules to understand the ex- tended

  14. Appl Phys B (2012) 107:619636 DOI 10.1007/s00340-012-4984-y

    E-Print Network [OSTI]

    Daraio, Chiara

    2012-01-01

    and optimised operation of gas turbine combustion systems, respectively, the development of cost- effective in the development of gas turbines F. Guethe · D. Guyot · G. Singla · N. Noiray · B. Schuermans Received: 10 October Abstract To optimise the operation of gas turbine combus- tors with respect to emission, cycle efficiency

  15. Submillimeter-resolution radiography of shielded structures with laser-accelerated electron beams

    E-Print Network [OSTI]

    Umstadter, Donald

    Submillimeter-resolution radiography of shielded structures with laser-accelerated electron beams (Received 24 March 2010; published 14 October 2010) We investigate the use of energetic electron beams-wakefield accelera- tors have been shown to produce electron beams with source sizes comparable to the laser beam

  16. TAO, Vol. 11, No. 4, 753-764, December 2000 A Rapid Method for the Determination of 137

    E-Print Network [OSTI]

    Huh, Chih-An

    - ronments from atomic bomb tests, nuclear accidents, and nuclear waste disposal. As an ele- ment, the determination of 137 Cs in aqueous systems can be applied to moni- tor the release of nuclear wastes-effective, and can be more easily performed aboard ships. (Key words: 137 Cs, Seawater, Copper hexacyanoferrates) 1

  17. IDA -A DESIGN ENVIRONMENT FOR ERGONOMIC USER INTERFACES

    E-Print Network [OSTI]

    Reiterer, Harald

    51 IDA - A DESIGN ENVIRONMENT FOR ERGONOMIC USER INTERFACES Harald Reiterer University of Vienna, Heuristic Evaluation, Standards, Style guides, Tools for Working with Guidelines, Usability Engineering not guarantee GUis of high ergonomic quality. To reach high ergonomic qualityGUls, human fac- tors knowledge has

  18. THRUST GENERATION DUE TO AIRFOIL FLAPPING Ismail H. Tuncer \\Lambda and Max F. Platzer y

    E-Print Network [OSTI]

    Tuncer, Ismail H.

    tests of an OH­6A helicopter significant reductions in main ro­ tor shaft torque and engine power­vortex interactions on helicopter blades, and the blade row interactions which occur in 1 #12; axial jet engines­ copter blades subjected to higher harmonic control was generated by Wood et al 7 who found in flight

  19. "Perfect" Electrochemical Molecular Sieving by Thin and Ultrathin Metallopolymeric Films

    E-Print Network [OSTI]

    such as membrane-based ultrafiltration and separa- tor-controlled fuel cell optimization. An interesting: In principle, optimization of these properties, together with binding properties, can contrib- ute tremendously to selective transport optimization is to prepare films of moderate or low thickness and then plug pinholes

  20. Orogenic movement mechanism for the formation of symmetrical relief features in copper nitride thin films

    E-Print Network [OSTI]

    Zexian, Cao

    Orogenic movement mechanism for the formation of symmetrical relief features in copper nitride thin heterogeneity, etc. In preparing thin films of the thermally unstable copper nitride Cu3N, growth proceeds-gap semiconduc- tors such as SiC and GaN that are expected to operate at temperatures over 300 °C demand both

  1. 30TH INTERNATIONAL COSMIC RAY CONFERENCE The Second Level Trigger of the PAMELA Space Experiment

    E-Print Network [OSTI]

    Morselli, Aldo

    . The experiment has a foreseen lifetime of at least 3 years. PAMELA is built around a permanent magnet silicon a permanent magnet spectrometer with a variety of specialized detec- tors [3]. In particular below the tracker, cosmic ray generation and propa- gation in our galaxy and the solar system, and to the study of solar

  2. scienceessays IDTL personnel and detector characterization

    E-Print Network [OSTI]

    Figer, Donald F.

    to select the best flight detector designs for JWST by evaluating prototype near-infrared detectors. Second as the sensors on the Hubble Space Telescope. In recognition of their importance to astronomy, the Institute selected the IDTL to verify comparative performance of prototype near-infrared JWST detec- tors developed

  3. JOURNAL OF MATERIALS SCIENCE 40 (2005) 64636472 Self-sensing of damage in carbon fiber

    E-Print Network [OSTI]

    Chung, Deborah D.L.

    2005-01-01

    , corrosion, thermal stress, lightning and various environmental fac- tors. For the purpose of hazard density. They are widely used for aircraft structures [6­8]. Due to the aging and safety requirement of aircraft, damage mon- itoring is critically needed for both military and civil aircraft. Self-sensing has

  4. Anthraquinone-Imide-Based Dimers: Synthesis, Piezochromism, Liquid Crystalline,

    E-Print Network [OSTI]

    Wan, Xin-hua

    -Infrared Electrochromic Properties Fengkun Chen, Jie Zhang, Xinhua Wan* Introduction Organic materials that respond-sensitive paints and shock detec- tors, for instance.[2] Since the early studies on piezochromic phenomena,[11­15] and poly(3-alkylthiophene),[16­21] inorganic metal complexes,[22,23] and some organic dyes.[24

  5. TOPOLOGICAL HOCHSCHILD HOMOLOGY AND THE CONDITION OF HOCHSCHILD-KOSTANT-ROSENBERG

    E-Print Network [OSTI]

    Larsen, Michael

    are commutative and unital. The base ring will usually be denoted k, and Hochschild homology, , and Tor commute with flat base change, so ker Ak /k = ker A/k k ; coker Ak /k = coker A/k k . As k is faithfully flat, the condition ker Ak /k = coker Ak /k = 0 implies that A/k is an isomorphism. 3 #12

  6. Two-Way Beacon Scheduling in ZigBee Tree-Based Wireless Sensor Networks , Meng-Shiuan Pan

    E-Print Network [OSTI]

    Tseng, Yu-Chee

    Two-Way Beacon Scheduling in ZigBee Tree-Based Wireless Sensor Networks Lun-Wu Yeh , Meng-way beacon scheduling prob- lem for ZigBee tree-based networks. We propose a schedul- ing algorithm that can sce- nario. The network contains one sink (ZigBee coordina- tor), some full-function devices (ZigBee

  7. Spring 2010 | PCI Journal Editor's quick points

    E-Print Network [OSTI]

    and a nonstructural wythe separated by a layer of insulation.1,2 A composite load-bearing SWP is typically fabricated and insulating material. The thickness of the concrete layers varies depending on the structural require- ments of the building. The most common load requirements include wind and seismic loads. Conventional shear connec- tors

  8. Developing Operator Models for UAV Search Scheduling L. F. Bertuccelli, N. W. M. Beckers, and M. L. Cummings

    E-Print Network [OSTI]

    Cummings, Mary "Missy"

    Developing Operator Models for UAV Search Scheduling L. F. Bertuccelli, N. W. M. Beckers, and M. L. Cummings With the increased use of Unmanned Aerial Vehicles (UAVs), it is envisioned that UAV opera- tors. In the context of search missions, operators supervising a large number of UAVs can be- come overwhelmed

  9. Top-of-Rail lubricant

    SciTech Connect (OSTI)

    Alzoubi, M. F.; Fenske, G. R.; Erck, R. A.; Boparai, A. S.

    2000-07-14

    Analysis of the volatile and semivolatile fractions collected after use of the TOR lubricant indicated that other than contaminants in the collection laboratory, no compounds on the EPA's Target Compound Lists (Tables 2 and 5) were detected in these fractions. The data of these qualitative analyses, given in the various tables in the text, indicate only the relative amounts of the tentatively identified compounds. The authors recommend that quantitative analysis be performed on the volatile and semivolatile fractions to allow confirmation of the tentatively identified compounds and to obtain absolute amounts of the detected compounds. Additionally, the semivolatile fraction should be analyzed by liquid chromatography/mass spectrometry to identify compounds that are not chromatographable under the temperature program used for determination of semivolatile compounds. Introducing the top-of-rail (TOR) lubricant into the wheel/rail interface results in a reduction of almost 60% of lateral friction force over the forces encountered under dry conditions. This reveals good potential for energy savings, as well as wear reduction, for railroad companies. In TOR lubrication, an increase in the angle of attack and axle load results in increased lateral friction and rate of lubricant consumption. The most efficient TOR lubricant quantity to be used in the wheel/rail interface must be calculated precisely according to the number of cars, axle loads, train speed, and angle of attack.

  10. Aerosol Science and Technology, 43:641652, 2009 Copyright American Association for Aerosol Research

    E-Print Network [OSTI]

    Aerosol Science and Technology, 43:641­652, 2009 Copyright © American Association for Aerosol Differential Mobility Analyzer for Measurement of the Irreversibility of the Hygroscopic Growth Factor T is the irreversibility of the hygroscopic growth fac- tor of aerosol particles. The instrument uses the hysteresis

  11. Laser-based processing of polymer nanocomposites for chemical sensing applications

    E-Print Network [OSTI]

    Zhigilei, Leonid V.

    used to fabricate polymer/carbon nanocomposite thin films for use in chemical sensors chemiresistors materials involves polymer-carbon composites for chemical sensing technologies. An example is the carbon-polymer chemiresis- tor, a device in which a carbon black-polymer composite is deposited between two or four

  12. Time Schedule Autumn Quarter 1986

    E-Print Network [OSTI]

    Doty, Sharon Lafferty

    : November 4-14 I · 1 #12;ZlFF-DAVIS SPECIAL MARKETS GROUP EcI1tor-in-Chlef and ~eral Manager Jeffrey A. Stem Group Publisher William S. David DIRECTORY OF CLASSES PresIdent Andrew C. Cltsay . Publisher Craig. ToohyAvenue Uncolnwood, illinois 60646 (312) 679-1100 WEST COAST Bill Curtis W.J. Curtis & Associates

  13. Novel Determinants of Intestinal Colonization of Salmonella enterica Serotype Typhimurium Identified in Bovine Enteric Infection

    E-Print Network [OSTI]

    2013-01-01

    effec- tor proteins SipA, SopA, SopB, SopD, and SopE2 act inLG, Bäumler AJ. 2005. SipA, SopA, SopB, SopD, and SopE2

  14. Sputtering of amorphous hydrogenated carbon by hyperthermal ions as studied by tight-binding

    E-Print Network [OSTI]

    Krasheninnikov, Arkady V.

    of the erosion of tokamak fusion reac- tor walls. This erosion occurs due to impacts of low-energy hydrogen ions, which accounts for the quantum-mechanical nature of the interactions between the impinging particle calculations; Interactions of atoms with surfaces; Plasma­ material interaction 1. Introduction One

  15. Contrib. Plasma Phys. 42 (2002) 2-4, 451-457 Tight-Binding Atomistic Simulations of Hydrocarbon

    E-Print Network [OSTI]

    Krasheninnikov, Arkady V.

    2002-01-01

    Sputtering by Hyperthermal Ions in Tokamak Diver- tors A.V. Krasheninnikova) , E. Salonena) , K. Nordlunda- anisms of the erosion of carbon-based fusion reactor walls by low-energy hydrogen ions coming from for the quantum-mechanical nature of impinging particle-surface interaction, we re-examine the low-energy erosion

  16. Natural versus forced convection in laminar starting plumes Michael C. Rogers and Stephen W. Morris

    E-Print Network [OSTI]

    Morris, Stephen W.

    fluid from a small, submerged outlet. The plumes were laminar and spanned a wide range of plume, the most important fac- tor determining jet or plume behaviour and evolution is whether the flow is laminar orNatural versus forced convection in laminar starting plumes Michael C. Rogers and Stephen W. Morris

  17. Abstract--We have recently completed a large-area, coded-aperture, gamma-ray imager for use in searching for radiation

    E-Print Network [OSTI]

    Horn, Berthold K.P.

    - strument [2] that makes a map of the radiation field as it trav- erses a region. The pixel size of the map in searching for radiation sources. The instrument was constructed to verify that weak point sources can sufficient radiation can reach a large gamma-ray detec- tor from a small source to make detection possible

  18. The continental shelf and upper slope of the Oregon Cascadia margin are underlain by an

    E-Print Network [OSTI]

    Goldfinger, Chris

    stratigraphy includes a regional late Miocene unconformity that may coincide with a worldwide hiatus ca. 7 and correlated seaward reflec- tor from seismic reflection data clearly out- lines deformation into major mar- gin. The basin stratigraphy contains several re- gional unconformities, suggesting a complex his

  19. J.J. Berezan is currently a M.Sc. graduate student

    E-Print Network [OSTI]

    Joseph, Tim Grain

    at the same university in 2002. He is supported in his research efforts by Syncrude Canada Ltd. Coal and Oil, University of Alberta, and V.D. del Valle, Syncrude Canada Ltd. KEYWORDS: Vibration, Heavy hauler, Opera- tor health, Onboard system. Paper reviewed and approved for publication by the Coal and Oil Sands Division

  20. Adaptive observer-based switched control for electropneumatic clutch actuator with

    E-Print Network [OSTI]

    Johansen, Tor Arne

    from a heavy duty test truck, showing no significant loss of performance due to lack of a pressure Hege Langjord Glenn-Ole Kaasa Tor Arne Johansen Department of Engineering Cybernetics, NTNU on design for implementation in a heavy duty truck system, and focus on performance evalution using

  1. Synthesis, assembly and degradation of thylakoid membrane proteins Yves Choquet, Olivier Vallon*

    E-Print Network [OSTI]

    this complex system is built up (structural genes, regula- tors and assembly catalysts). The 3D synthesis. These complexes are built from a large number of polypeptide subunits encoded either of coordination appears necessary, not only to avoid wasteful production of subunits in excess of their assembly

  2. Evaluation of Anonymized ONS Queries J. G. Alfaro (joaquin.garcia-alfaro@acm.org),

    E-Print Network [OSTI]

    Garcia-Alfaro, Joaquin

    is the use of online anonymity. We present an evaluation experiment that compares the of use of Tor (The second generation Onion Router) on a global ONS/DNS setup, with respect to benefits, limitations, Onion Routing, Anonymity. 1 Introduction Electronic Product Code (EPC) is a low-cost technology, based

  3. A Model of Onion Routing with Provable Joan Feigenbaum1

    E-Print Network [OSTI]

    Feigenbaum, Joan

    design, Tor [6], consists of over 750 routers, each processing an average of 100KB/s. Onion routingA Model of Onion Routing with Provable Anonymity Joan Feigenbaum1 , Aaron Johnson1 , and Paul@itd.nrl.navy.mil Abstract. Onion routing is a scheme for anonymous communication that is designed for practical use. Until

  4. SGor: Trust graph based onion routing Peng Zhou a,

    E-Print Network [OSTI]

    Ives, Zachary G.

    routers pose a serious threat to existing onion routing networks (e.g., the Tor network [14]). To thwartSGor: Trust graph based onion routing Peng Zhou a, , Xiapu Luo a , Ang Chen b,1 , Rocky K.C. Chang August 2013 Available online 24 August 2013 Keywords: Trust graph Anonymity Onion routing a b s t r a c

  5. Bulletin of Tibetology: Volume 17 Number 4 : Full issue

    E-Print Network [OSTI]

    Namgyal Institute of Tibetology

    1981-11-18

    tor ,common :moflks .aaprr,ing ,far ,Arhata·~. Iii} The '!'fana ofsert realised Gshen. :11 'has 1WO 'sspects:- ,a) T.he Sraxrakayana .accorning ,to '.which externalmOnion (tsong) Amdo in North East Tibet popularly known as Tsong Khapa, Je Rinpoche, Lobsang dakpa (Sumatikirti), he was the founder...

  6. Pairing-Based Onion Routing with Improved Forward Secrecy Aniket Kate Greg M. Zaverucha Ian Goldberg

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    to scale gracefully. Keywords: onion routing, Tor, pairing-based cryptography, anonymous key agreementPairing-Based Onion Routing with Improved Forward Secrecy Aniket Kate Greg M. Zaverucha Ian {akate,gzaveruc,iang}@cs.uwaterloo.ca Abstract This paper presents new protocols for onion routing

  7. Traffic Analysis Attacks and Defenses in Low Latency Anonymous Communication

    E-Print Network [OSTI]

    Keromytis, Angelos D.

    the true network identity of com- municating parties against eavesdropping adversaries. Tor, acronym for The Onion Router, is an example of such a system. Such systems relay the traffic of their users through an overlay of nodes that are called Onion Routers and are operated by volunteers distributed across the globe

  8. Core and periphery in Free/Libre and Open Source software team communications

    E-Print Network [OSTI]

    Crowston, Kevin

    of developers, a Bradford's law analysis that takes as the core the most frequent contribu- tors and a social a highly skewed distribution of traffic on the Linux mailing lists. The suggested hierarchical or onion-like structure is shown in Figure 1. At the center of the onion are the core developers, who contribute most

  9. Denial of Service or Denial of Security? How Attacks on Reliability can Compromise Anonymity

    E-Print Network [OSTI]

    Danezis, George

    of traditional high- and low-latency anonymous communication systems, as well as on the Hydra-Onion and Cashmere networks, showing that they cannot tolerate a majority of nodes be- ing malicious. Cashmere, Hydra-Onion and high-latency anonymous systems. The low- latency systems are exemplified by Tor, a popular anony- mou

  10. Empirical Tests of Anonymous Voice Over IP Marc Liberatoreb,

    E-Print Network [OSTI]

    Wright , Matthew

    Proxy Proxy Contact Anonymous Voice over IP (aVoIP) Initiator Proxy Proxy Proxy The Onion Router (Tor for extending onion-routing style anonymity protocols for supporting anonymous VoIP (aVoIP) traffic show that aVoIP could be developed in an onion routing system with reasonable performance guarantees

  11. The University of Texas at Austin Department of Computer Science

    E-Print Network [OSTI]

    Johnson, Aaron

    -latency anonymous communication protocols in gen- eral, and the popular onion-routing protocol in particular bandwidth. We also per- form measurements on the Tor network to estimate the real-world per- formance of our of sending a large number of extra messages. Protocols such as onion routing [16] Supported in part by NSF

  12. Anonymity Analysis of Onion Routing in the Universally Composable Framework

    E-Print Network [OSTI]

    Johnson, Aaron

    deployed anonymous communications systems. The Tor onion routing network currently comprises some threeAnonymity Analysis of Onion Routing in the Universally Composable Framework Joan Feigenbaum Yale. Specifically we present a probabilistic analysis of onion routing in a black-box model of anonymous

  13. Provable Anonymity Flavio D. Garcia Ichiro Hasuo Wolter Pieters Peter van Rossum

    E-Print Network [OSTI]

    Garcia, Flavio D.

    the basis of Onion Routing [9] and its successor Tor [6], a currently running network of relays providing and unlinkability for two anonymizing protocols, Onion Rout- ing and Crowds. Moreover, we consider a version of Onion Routing in which we inject a subtle error and show how our framework is capable of capturing

  14. Report on the Sixth ACM Workshop on Privacy in the Electronic Society (WPES 2007)

    E-Print Network [OSTI]

    approaches include mix networks, DC-net, Freenet, Onion Routing and Crowds. Many anonymous systems have also been developed and deployed (e.g., Tor, Freenet, AP3 and GNUnet). The first paper in this session was entitled "Probabilis- tic Analysis of Onion Routing in a Black-box Model." It quantitatively studied how

  15. Pairing-Based Onion Routing with Improved Forward Secrecy

    E-Print Network [OSTI]

    Goldberg, Ian

    , Security Additional Key Words and Phrases: Onion routing, Tor, pairing-based cryptography, anonymous key29 Pairing-Based Onion Routing with Improved Forward Secrecy ANIKET KATE, GREG M. ZAVERUCHA, and IAN GOLDBERG University of Waterloo This article presents new protocols for onion routing anonymity

  16. Design and Analysis of Efficient AnonymousCommunication

    E-Print Network [OSTI]

    Feigenbaum, Joan

    .penet.fi · Mixmaster · Tor · AN.ON 4 #12;Anonymous Communication in Research · Mix networks (Chaum, CACM, 1981) · Dining cryptographers (Chaum, Journal of Cryptology, 1988) · Onion routing (Goldschlag et al and analyze onion routing. 7 #12;Problem 1: Efficient protocols are useful but not rigorously understood

  17. Peer-to-Peer Anonymous Networking Using Coding Christopher S. Chang1, Tracey Ho2, and Michelle Effros2

    E-Print Network [OSTI]

    Ho, Tracey

    , to the "onion routing" approach of Reed et al. [2] and the Tor protocol [3] which is the most widely used). As in the "slicing the onion" scheme proposed by Katti et al., a sender constructs a layered subgraph over which on onion routing), MorphMix [5] (similar to Tarzan but where the routes are determined by intermediaries

  18. Pairing-Based Onion Routing Aniket Kate, Greg Zaverucha, and Ian Goldberg

    E-Print Network [OSTI]

    Goldberg, Ian

    . #12;2. We use our protocol to build onion routing circuits for anonymity networks like Tor [7]. OurPairing-Based Onion Routing Aniket Kate, Greg Zaverucha, and Ian Goldberg David R. Cheriton School in onion routing anonymity networks. Instead of iteratively and interactively constructing circuits

  19. Trust-based Anonymous Communication: Adversary Models and Routing Algorithms

    E-Print Network [OSTI]

    Johnson, Aaron

    Mathewson The Tor Project {arma, nickm}@torproject.org ABSTRACT We introduce a novel model of routing parts of the network. We focus on anonymous communication, and in particular onion routing, although we present as an example a new algorithm to select paths in onion routing. We analyze its effectiveness

  20. 60 Prism-Magazine.org by tom KatsouLeas

    E-Print Network [OSTI]

    of exciting ones. We have also learned that this generation of stu- dents wants to get involved. To capitalize- tors is to tap into that energy and give what it needs to succeed. Engineering fundamentals tradeoffs for the social and environmental cost of hydrocarbon combustion. Electric cars may be viable

  1. Evaluation of Cell Culture Exercise Protocols using a Mechanical Stretch System for Analysis of DEPTOR Expression 

    E-Print Network [OSTI]

    Wudeck, Elyse Victoria

    2013-02-04

    is DEPTOR, which acts as a negative inhibitor of mTOR expression and decreases the rate of protein synthesis. Recent data in our lab has revealed that DEPTOR is differentially expressed in scenarios of diabetes, disuse, and exercise, suggesting that DEPTOR...

  2. NUCLEAR SCIENCE AND ENGINEERING: 158, 164193 ~2008! Multifractal Analysis of Chaotic Flashing-Induced Instabilities in

    E-Print Network [OSTI]

    Demazière, Christophe

    of forced-circulation boiling water reac- served experimentally in a number of cases since then.10 tors-Induced Instabilities in Boiling Channels in the Natural-Circulation CIRCUS Facility Christophe Demazière* Chalmers of Nuclear Reactors, Delft, 2629 BJ, The Netherlands Received October 30, 2006 Accepted May 12, 2007

  3. Multifractal Analysis of Chaotic Flashing-Induced Instabilities in Boiling Channels in the Natural-Circulation CIRCUS Facility

    E-Print Network [OSTI]

    Demazière, Christophe

    . INTRODUCTION Instability of forced-circulation boiling water reac- tors ~BWRs!, which is manifested by selfMultifractal Analysis of Chaotic Flashing-Induced Instabilities in Boiling Channels in the Natural University of Technology, Department of Physics of Nuclear Reactors, Delft, 2629 BJ, The Netherlands Received

  4. Explosive vaporization in microenclosures G. Romera-Guereca a,*, J. Lichtenberg b

    E-Print Network [OSTI]

    Daraio, Chiara

    of a small liquid volume (8 nL) heated by a electric pulse for 2 ls supplied to a planar microfabricated of 107 K sÀ1 for a pulse duration of 2 ls. We compare bubble growth and collapse for the open and closed for microreac- tors [5] and as microinjector mechanism to improve fuel injection in internal combustion engines

  5. Predators: Good Will Mobile Codes Combat against Computer Viruses

    E-Print Network [OSTI]

    Khan, Javed I.

    Predators: Good Will Mobile Codes Combat against Computer Viruses Hiroshi Toyoizumi Performance approach to fight against computer viruses through the use of their predators. Preda- tors are good will mobile co,des which, like viruses, travel over computer networks, and replicate and multipy themselves

  6. ccsd-00001341(version1):23Mar2004 Hanbury-Brown Twiss correlations to probe the population

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    ccsd-00001341(version1):23Mar2004 Hanbury-Brown Twiss correlations to probe the population the first study of the statistics of GHz photons in quantum circuits, using Hanbury- Brown and Twiss experiment of Hanbury-Brown and Twiss (HBT)[1], consisted in two detec- tors correlating the power

  7. Radiation dose reduction and image enhancement in biological imaging through equally-sloped tomography

    E-Print Network [OSTI]

    Miao, Jianwei "John"

    Radiation dose reduction and image enhancement in biological imaging through equally Iterative reconstruction algorithm Radiation dose reduction Image enhancement Computed tomography a b s t r, 1974; Dubochet et al., 1998). The use of electronic detec- tors and the implementation of automated low-dose

  8. IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS FOR VIDEO TECHNOLOGY, VOL. 11, NO. 5, MAY 2001 603 Semantic Video Object Extraction Using Four-Band

    E-Print Network [OSTI]

    Gatica-Perez, Daniel

    IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS FOR VIDEO TECHNOLOGY, VOL. 11, NO. 5, MAY 2001 603 the problem of multiple semantic video object (SVO) extraction as an issue of designing extensive opera- tors- rates an edge-driven marker extraction algorithm and a growing method which integrates both color

  9. November 6, 2012 u vol. 109 u no. 45 u 1823518626 ProceedingsoftheNationalAcademy ofSciences of theUnitedStates ofAmerica www.pnas.org

    E-Print Network [OSTI]

    Goldstein, Allen

    insights into SOA formation from mo- tor vehicles, and may lead to improved pollution con- trol policies and diesel vehicles to air pollution Vehicles at the entrance of the Caldecott Tunnel in Oakland, CA and diesel vehicles contribute to the formation of second- ary organic aerosol (SOA), tiny particles that can

  10. Paul J. Rudershausen is with the North Caro-lina State University Department of Biology,

    E-Print Network [OSTI]

    of gear design and environmental fac- tors (location, soak time, bottom type, and sea surface water:pjruders@ncsu.edu). doi: dx.doi.org/10.7755/MFR.75.3.2 Gear Modifications for Fishing Octopus, Octopus vulgaris, on Live that can catch it. This study sought to: 1) determine those gear and en- vironmental factors

  11. Assessment of the Distribution and Abundance of Coastal Sharks in the U.S. Gulf of Mexico

    E-Print Network [OSTI]

    nautical mile gridfrom Browns ville, Tex. to Cape Ann, Mass. The survey meth odology and gear design used gram and survey design to address this need has been difficult due to factors that include species diversity, geo graphic distributions, seasonality, and gear selectivity. Since all of these fac tors

  12. UNUSUALLY WEAK DIFFUSE INTERSTELLAR BANDS TOWARD HD 62542 Theodore P. Snow,1

    E-Print Network [OSTI]

    McCall, Benjamin J.

    UNUSUALLY WEAK DIFFUSE INTERSTELLAR BANDS TOWARD HD 62542 Theodore P. Snow,1 Daniel E. Welty,2 approaches were made to the task of identifying the carriers (see Herbig 1995 or Snow 1995, 2001 for recent conclusions (Snow, York, & Welty 1977). With the advent of electronic detec- tors in the 1970s, however

  13. proteinsSTRUCTURE O FUNCTION O BIOINFORMATICS pH-dependent molecular dynamics of vesicular

    E-Print Network [OSTI]

    Ullmann, G. Matthias

    occur during the fusion process [Fig. 1(A,B)]. The prefusion structure is rather compact Bayreuth, Germany INTRODUCTION For coated viruses, fusion of the virus membrane with the host cell membrane family have only one surface glycopro- tein, glycoprotein G, representing the sole fusion media- tor3

  14. Report of the 90-Day Study on Human Exploration of

    E-Print Network [OSTI]

    Rathbun, Julie A.

    and one data acurce tor Council consideration of approaches to program, achedule and .technology planning. cost. The report does not contain any specific recommendations. The tQport does not contain any travelers, but also extending into the solar system the skills, imagination, and support of many thousands

  15. Electrical conductivity and current-voltage characteristics of alumina with or without neutron and electron irradiation

    E-Print Network [OSTI]

    Howlader, Matiar R

    irradiation. Radiation induced conductivity (RIC) was observed for all speci- mens under neutron and electron of the leading candidates for insula- tor and radiofrequency window/feedthrough applica- tions in magnetic fusion of alumina. Radiation induced conductivity (RIC) and radiation induced electrical de- gradation (RIED

  16. The Village Base Station Kurtis Heimerl

    E-Print Network [OSTI]

    California at Berkeley, University of

    deployment due to low power requirements that enable local generation via solar or wind; · explicit support. At around 20W, its power consumption is low enough to avoid diesel genera- tors and the corresponding damaging equipment [2]. We propose operating the entire base station on solely wind or solar power, which

  17. NANOELECTRONICS , C. Delerue, C. Krzeminski

    E-Print Network [OSTI]

    will replace the present day MOS (metal-oxide-semiconductor) based technology. This is exactly the essence larger structures with fundamentally new molecular organization. This should lead to novel materials and Atalla [1] demonstrated in 1960 the first metal-oxide semiconductor field effect transis- tor (MOSFET

  18. AnonymousCloud: A Data Ownership Privacy Provider Framework in Cloud Computing

    E-Print Network [OSTI]

    Hamlen, Kevin W.

    AnonymousCloud: A Data Ownership Privacy Provider Framework in Cloud Computing Safwan Mahmud Khan their computation results are ultimately delivered. To provide this data ownership privacy, the cloud's distributed-anonymity; authentication; cloud computing; in- formation security; privacy; Tor I. INTRODUCTION Revolutionary advances

  19. Nanopatterning of Catalyst by Dip Pen Nanolithography (DPN) for Synthesis of Carbon Nanotubes (CNT)

    E-Print Network [OSTI]

    Banerjee, Debjyoti

    for applications in high-efficiency energy storage systems, nanoscale-integrated circuits or sensors, as well nanolithography technique was used to deposit NiCl2 nanopatterns with sub- 200 nm feature sizes on a silicon-effect transis- tor (FETs), and can provide capabilities not possible with conventional silicon-based FETs (Javey

  20. Astronomical Data Analysis Software and Systems XVIII ASP Conference Series, Vol. 411, c 2009

    E-Print Network [OSTI]

    Taylor, Mark

    . STILTS is a mature and powerful package for all kinds of table manip- ulation, and this version adds, and textual point labeling. Vec- tor and bitmapped output formats are supported. The plotting options provide 2006) is a mature package of command-line utilities which provides many kinds of table manipulation

  1. Transportation Research Record: Journal of the Transportation Research Board, No. 2340, Transportation Research Board of the National Academies, Washington,

    E-Print Network [OSTI]

    Bertini, Robert L.

    in the United States show that CO2 emissions are the dominant GHG from the transportation sec- tor, with medium-duty and HD trucks emitting 22% of domestic transportation-related CO2 (2). CO2 emissions are directly linked by emissions of mobile source air toxics (MSAT) is growing. MSAT are compounds emitted from mobile sources

  2. Diagnostics of ballistic electrons in a dc/rf hybrid capacitively coupled discharge

    E-Print Network [OSTI]

    Economou, Demetre J.

    Diagnostics of ballistic electrons in a dc/rf hybrid capacitively coupled discharge Lin Xu,1,a Lee the substrate electrode or the semiconduc- tor wafer. Watanabe et al.7 superimposed a high energy electron beam. Economou,2,c and Vincent M. Donnelly2,d 1 Tokyo Electron America, Austin, Texas 78741, USA 2 Department

  3. Network Worms ecentincidentshavedemonstratedtheabilityof

    E-Print Network [OSTI]

    Keromytis, Angelos D.

    critical infrastruc- ture such as the transportation, finance, and energy sec- tors. Even when a worm carries no malicious payload, there are tremendous direct recovery costs from an infec- tion epidemic uses sensors to detect potential in- fection vectors; to test potential fixes, we use a clean

  4. Nuclear Instruments and Methods in Physics Research A 572 (2007) 333334 PAMELA Data Acquisition System

    E-Print Network [OSTI]

    Morselli, Aldo

    2007-01-01

    -of-Flight), spectrometer, calorimeter, an anticoincidence system and a neutron detector, the experiment has an on a trigger is delivered by the trigger system. Monitoring the busy line status, the trigger system has System Alessandro Basili INFN sez.di Roma Tor Vergata, 00133 Rome, Italy on the behalf of the PAMELA

  5. N J I T M A G A Z I N E | F A L L 2 0 1 2 1 5 disciplinEs

    E-Print Network [OSTI]

    Haimovich, Alexander

    on three vital areas ­ convergent life science and engineering, "digital everyware" ­ ubiquitous computing for learning. However, their alignment with industries of the future is not as obvious as with those sec- tors that convergent life science and engineering, digital everyware and sustainable systems ­ themes that transcend

  6. This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research

    E-Print Network [OSTI]

    Stølen, Ketil

    ., 2006). One example, from the Nordic power sec- tor, is the situation with reduced hydro power capacity in southern Norway and full hydro power capacity in Sweden (Doorman et al., 2004). In this situation such as the electric power supply or telecommunications is complicated by the fact that such infrastructures

  7. A MULTI-MICROPHONE BEAMFORMER WITH AN EIGENDOMAIN POST-FILTER Firas Jabloun and Beno^it Champagne

    E-Print Network [OSTI]

    Champagne, Benoît

    is also considered. Experimental results us- ing different objective measures are reported. 1 is the noise vec- tor with covariance matrix Rw. The eigenvalue decomposi- tion (ED) of the covariance matrix 's in decreasing order. In this pa- per, we also assume that the noise is white with Rw = 2 I so

  8. D Riso-R-429 Automated Uranium

    E-Print Network [OSTI]

    -2840 Risø repro 1980 #12;- 3 - CONTENT Page 1. INTRODUCTION 5 2. PHYSICAL PRINCIPLES 7 3. INSTRUMENTATION 8 installed at various reactor centres. Davies and Cole (1964) reported on a facility at the Herald reac- tor) described the U and the Th analysis of powdered rocks for geochronological studies at the same reactor

  9. Short History of the University ..........................................2 Leadership .......................................................................3

    E-Print Network [OSTI]

    Acton, Scott

    . Senior Advisor to the Board LEADErShiP FOr mOrE iNFOrmATiON, ViSiT ThE BOArD OF ViSiTOrS wEBSiTE: www.virginia.edu/bov

  10. Proc. of NSF Design and Manufacturing Grantees Conference, San Diego, CA, January 46, 1995 C H Shell for Integration of Mechatronic Systems

    E-Print Network [OSTI]

    Cheng, Harry H.

    Shell for Integration of Mechatronic Systems Harry H. Cheng Department of Mechanical and Aeronautical for integration of mechatronic systems for agile manufacturing. 1 Introduction Agile manufacturing is charactered is not as important as ease of integration of mechatronic devices that include stepper mo­ tors, DC and AC motors

  11. 94 Chemical Engineering Education MICROMIXING EXPERIMENTS

    E-Print Network [OSTI]

    Hesketh, Robert

    94 Chemical Engineering Education MICROMIXING EXPERIMENTS In the Introductory Chemical Reaction aspects of chemical re- action engineering. A major priority in industrial reac- tors[1] is to optimize of the introductory undergraduate chemical reaction engineer- ing course, but the experiments described in this paper

  12. Scenario-Based Fault-Tolerant Model Predictive Control for Diesel-Electric Marine Power Plant

    E-Print Network [OSTI]

    Johansen, Tor Arne

    Scenario-Based Fault-Tolerant Model Predictive Control for Diesel-Electric Marine Power Plant Email: torstein.bo@itk.ntnu.no, tor.arne.johansen@itk.ntnu.no Abstract--Diesel-electric propulsion generation control, Ma- rine safety, Optimal control. I. INTRODUCTION Diesel electric propulsion is a system

  13. Free-Piston Diesel Engine Timing and Control { Towards Electronic Cam-and Crankshaft

    E-Print Network [OSTI]

    Johansen, Tor Arne

    1 Free-Piston Diesel Engine Timing and Control { Towards Electronic Cam- and Crankshaft Tor A. Johansen, Olav Egeland, Erling Aa. Johannessen and Rolf Kvamsdal Abstract| The free-piston diesel engine replaces the crankshaft of the traditional diesel engine with a power tur- bine to convert energy from

  14. 9.7 eggs (Bengtson 1972b). Incubation, by O alone, 2628 days and starts on completion of clutch. o

    E-Print Network [OSTI]

    Afton, Alan D.

    susceptibility to oil pollution when moulting and in winter. In Caspian Sea, thought to be less numerous than previously because of oil pollution.Also may be susceptible to accumulation of high levels of organochlorine thermal properties of plumage as suggested for Lesser Scaup (Stephenson 1997). Use as biomoni- tors

  15. First-principles study of Mn-induced local magnetic moments in host semiconductors Shi-Hao Wei

    E-Print Network [OSTI]

    Gong, Xingao

    230031, China Gustavo M. Dalpian and Su-Huai Wei National Renewable Energy Laboratory, Golden, Colorado the high energy state, thus lowering the total energy. In the case where no hole is present, such as in Cd lowering the total energy.1,5 However, recent discovery that Mn-doped III-V semiconduc- tors can have

  16. Temperature-and electric-field-dependent domain structures and phase transformations in ,,001...-cut tetragonal

    E-Print Network [OSTI]

    applications in medical imaging, actua- tors, sonar, and accelerometers. The exceptional piezoelectric piezoelectric coeffi- cient d33 2500 pC/N , a large strain level up to 1.7% , and low hysteresis.1 Such high piezoelectric performance, which converts mechanical and electric energies, gives ex- tremely promising

  17. GEOCHEMISTRY AND AR GEOCHRONOLOGY

    E-Print Network [OSTI]

    Cohen, Barbara Anne

    committee members ­ Tim Swindle, David Kring, Mike Drake, Bill Boynton, and Sue Baldwin ­ contributed officemates Mike, Bill, and Kim showed me how it was done, and Andy, Jen, Betty, Doug, Chris, David, and Nancy- tors there ­ Dan Davis and Don Lindsley ­ started me on my PhD pursuit, and indeed my career. Even

  18. The Crystallographic Structure of Phytohemagglutinin-L* (Received for publication, December 7, 1995, and in revised form, March 25, 1996)

    E-Print Network [OSTI]

    Hamelryck, Thomas

    ., 1994), which exists in at least six electrophoretic forms, and an -amylase inhibitor (Moreno and Chrispeels, 1989). Arcelin and -amylase inhibi- tor can be considered as truncated forms of PHA, in which properties. Both ar- celin (Osborn et al., 1988) and -amylase inhibitor (Shade et al., 1994) protect bean

  19. Ultrafast Vibrationally-Induced Dephasing of Electronic Excitations in

    E-Print Network [OSTI]

    -3-1 Hongo, Bunkyoku, Tokyo 113-8656, Japan, and Theory DiVision, Los Alamos National Lab, New Mexico 87545 solar cells,5 field-effect transis- tors,6 and other nanometer-sized devices. The quasi because of its potential for extraordinary improvement of solar-cell efficiencies. In traditional solar

  20. Optimization of experimental design in fMRI: a general framework using a genetic algorithm

    E-Print Network [OSTI]

    that outperform random designs on all three criteria simultaneously. © 2003 Elsevier Science (USA). All rights of fMRI designs using novel criteria or existing criteria for design fitness (e.g., Dale, 1999; FristonOptimization of experimental design in fMRI: a general framework using a genetic algorithm Tor D

  1. Analysis of the Stability and Performance of Exponential Backoff

    E-Print Network [OSTI]

    , N. The analysis considers the general case of EB with backoff fac- tor r, where BEB is the special for the channel. A widely used collision resolution pro- tocol is the binary exponential backoff (BEB), forms the stability of BEB and analyze its perfor- mance using a model that closely resembles practical network

  2. Analysis of the Stability and Performance of Exponential Backoff

    E-Print Network [OSTI]

    , N . The analysis considers the general case of EB with backoff fac­ tor r, where BEB is the special for the channel. A widely used collision resolution pro­ tocol is the binary exponential backoff (BEB), forms the stability of BEB and analyze its perfor­ mance using a model that closely resembles practical network

  3. Atmos. Chem. Phys., 12, 14491480, 2012 www.atmos-chem-phys.net/12/1449/2012/

    E-Print Network [OSTI]

    Meskhidze, Nicholas

    conditioning systems in cars, and contrails. For the year 2000, the CO2 emissions from all sectors together) emissions from these transport sec- tors, most of their non-CO2 emissions are also taken into account, i.e. the forcing from ozone, methane, black car- bon, organic carbon, sulfate, CFC-12 and HFC-134a from air

  4. Practical Issues in Compiling Typed Unification Grammars for Speech Recognition

    E-Print Network [OSTI]

    and for some research systems (Moore et al. 1997, Rayner et al. 2000, Lemon et al. 2001, Gauthron and Colineau. This approach has been used in several systems, CommandTalk (Moore et al. 1997), RIALIST PSA simula- tor (Rayner conceed that alternative tech- niques that are not sound (Black 1989, (Johnson 1998, Rayner and Carter

  5. Constrained Nonlinear Control Allocation with Singularity Avoidance using Sequential Quadratic

    E-Print Network [OSTI]

    Johansen, Tor Arne

    of this paper is that the cost function used for optimizing control allocation includes a term that penalizes1 Constrained Nonlinear Control Allocation with Singularity Avoidance using Sequential Quadratic Programming Tor A. Johansen£ , Thor I. Fossen£ and Svein P. Berge££ Abstract-- Control allocation problems can

  6. Thrust allocation with power management functionality on dynamically positioned vessels

    E-Print Network [OSTI]

    Johansen, Tor Arne

    Thrust allocation with power management functionality on dynamically positioned vessels Aleksander Veksler,1 Tor Arne Johansen,1 Roger Skjetne2 Abstract--A thrust allocation method with capabilities are fairly straightforward. Index Terms--Thrust Allocation, Surface Vessels, Power Man- agement I

  7. An Application of Transfer to American Football: From Observation of Raw Video to Control in a Simulated Environment

    E-Print Network [OSTI]

    An Application of Transfer to American Football: From Observation of Raw Video to Control of transferring knowledge of American football from video observation to control in a game simula- tor. We trace for transferring knowledge between two tasks in Amer- ican football. In the initial task, known as the source

  8. ELSEVIER Physica B 213&214 11995J454 458 Neutron scattering from liquid 3He

    E-Print Network [OSTI]

    Glyde, Henry R.

    ELSEVIER Physica B 213&214 11995J454 458 HIYSICA[ Neutron scattering from liquid 3He at large Abstract Neutron inelastic scattering measurements have been made on liquid 3He at 1,4 K for wave vectors to investigate the neutron inelastic scattering from liquid 3He at T = 1.4 K for wave vec- tors between 9 and 20

  9. Appl. Phys. A 74, 345348 (2002) / Digital Object Identifier (DOI) 10.1007/s003390201275 Applied Physics A

    E-Print Network [OSTI]

    Liu, Jie

    2002-01-01

    on aerogel-supported catalyst B. Zheng, Y. Li, J. Liu Department of Chemistry, Duke University, Durham, NC monoxide on an aerogel-supported Fe/Mo catalyst. A simple acidic treat- ment followed by an oxidation of amorphous-carbon coating. Several fac- tors that affect the yield and the quality of the SWNTs were also

  10. Movement Imitation with Nonlinear Dynamical Systems in Humanoid Robots

    E-Print Network [OSTI]

    Baltes, Jacky

    Movement Imitation with Nonlinear Dynamical Systems in Humanoid Robots Auke Jan Ijspeert & Jun movement plans based on a set of nonlinear differential equations with well-defined attrac- tor dynamics of an adjustable pattern generator built from simple nonlinear autonomous dynamical sys- tems. The desired

  11. ARMOR: Analyzer for Reducing Module Operational Risk Michael R. Lyu

    E-Print Network [OSTI]

    Lyu, Michael R.

    contained in software systems or modules. To model software risk the quality indica­ tors of software and establishment of quality index of software programs. However, few tool can both perform sophisticated risk for Reducing Module Operational Risk) is a software risk analysis tool which automati­ cally identifies

  12. Deterministic Extractors For Small-Space Sources Jesse Kamp

    E-Print Network [OSTI]

    Vadhan, Salil

    random sources can also arise in cryptography when an adversary learns some partial information aboutDeterministic Extractors For Small-Space Sources Jesse Kamp Department of Computer Science-time, deterministic randomness extrac- tors for sources generated in small space, where we model space s sources on {0

  13. Deterministic Extractors For SmallSpace Sources Jesse Kamp #

    E-Print Network [OSTI]

    Vadhan, Salil

    random sources can also arise in cryptography when an adversary learns some partial information aboutDeterministic Extractors For Small­Space Sources Jesse Kamp # Department of Computer Science­time, deterministic randomness extrac­ tors for sources generated in small space, where we model space s sources on {0

  14. Over the past 20 years, our understanding of the physiological and molecular interactions

    E-Print Network [OSTI]

    Read, Andrew

    parasites, such as Plasmodium spp. and dengue virus, and their mosquito vectors1­3 has been radically. In particular, mosquito resistance to infection tends to be viewed as a static phenotype con- sisting solely that mosquito susceptibility to vector-borne parasites depends not only on genetic fac- tors, but also on a wide

  15. AUTOMATIC WEB VIDEO CATEGORIZATION USING AUDIO-VISUAL INFORMATION AND HIERARCHICAL CLUSTERING RELEVANCE FEEDBACK

    E-Print Network [OSTI]

    Widmer, Gerhard

    AUTOMATIC WEB VIDEO CATEGORIZATION USING AUDIO-VISUAL INFORMATION AND HIERARCHICAL CLUSTERING of Savoie, 74944 France, patrick.lambert@univ-savoie.fr ABSTRACT In this paper, we discuss and audio-visual approach to auto- matic web video categorization. We propose content descrip- tors which exploit audio

  16. DISTRIBUTION, ABUNDANCE, AND AGE AND GROWTH OF THE TOMTATE, HAEMULON AUROLINEATUM, ALONG THE

    E-Print Network [OSTI]

    THE SOUTHEASTERN UNITED STATES COAST! CHARLES S. MANOOCH 111 2 AND CHARLES A. BARANS s ABSTRACT Tomtates, Haemulon grunt (Haemulidae), which occurs from Cape Cod, Mass., to Brazil, including the Caribbean, Gulf. aurolineatum, and Haemulon rima- tor (Courtenay.1961), is known vernacularly as xira in Brazil; cuji

  17. Neuron, Vol. 24, 715726, November, 1999, Copyright 1999 by Cell Press ERK Plays a Regulatory Role in Induction

    E-Print Network [OSTI]

    Kobilka, Brian

    Neuron, Vol. 24, 715­726, November, 1999, Copyright ©1999 by Cell Press ERK Plays a Regulatory Role of long-term potentiation (LTP). Inhibi- tors of ERK signaling reduce LTP evoked by repeated high to the roles of ERK in persistent cellular Danny G. Winder,*§ Kelsey C. Martin,* Isabel A. Muzzio,* Daniel

  18. Maternal diet-induced obesity programmes cardiovascular dysfunction in adult male mouse offspring independent of current body weight

    E-Print Network [OSTI]

    Blackmore, Heather L.; Niu, Youguo; Fernandez-Twinn, Denise S.; Tarry-Adkins, Jane L.; Giussani, Dino A.; Ozanne, Susan E.

    2014-07-18

    , Siggens L, et al. The pro- gramming of cardiac hypertrophy in the offspring by maternal obe- sity is associated with hyperinsulinemia, AKT, ERK, and mTOR activation. Endocrinology. 2012;153(12):5961–5971. 14. Fan X, Turdi S, Ford SP, et al. Influence...

  19. Maternal Diet-induced Obesity Programs Cardiovascular Dysfunction in Adult Male Mouse Offspring Independent of Current Body Weight

    E-Print Network [OSTI]

    Blackmore, Heather L.; Niu, Youguo; Fernandez-Twinn, Denise S.; Tarry-Adkins, Jane L.; Giussani, Dino A.; Ozanne, Susan E.

    2014-07-22

    , Siggens L, et al. The pro- gramming of cardiac hypertrophy in the offspring by maternal obe- sity is associated with hyperinsulinemia, AKT, ERK, and mTOR activation. Endocrinology. 2012;153(12):5961–5971. 14. Fan X, Turdi S, Ford SP, et al. Influence...

  20. Production Optimization; System Identification and Uncertainty Steinar M. Elgsaeter

    E-Print Network [OSTI]

    Johansen, Tor Arne

    Slupphaug Tor Arne Johansen 1 Abstract Real-time optimization of oil and gas production requires of a North Sea oil and gas field. In offshore oil and gas production, the suggested method is ex- pected of offshore oil and gas fields, can be considered the total output of production wells, a mass flow

  1. Measurement of Regional Lung Function in Rats Using Hyperpolarized 3

    E-Print Network [OSTI]

    Measurement of Regional Lung Function in Rats Using Hyperpolarized 3 Helium Dynamic MRI Ben T. Chen,* Anja C.S. Brau, and G. Allan Johnson Dynamic regional lung function was investigated in rats using by a constant flow ventila- tor. Based on regional differences in the behavior of inspired air, the lung

  2. Planning Single-arm Manipulations with N-Arm Robots

    E-Print Network [OSTI]

    Likhachev, Maxim

    Planning Single-arm Manipulations with N-Arm Robots Benjamin Cohen bcohen@seas.upenn.edu University@cs.cmu.edu Carnegie Mellon University Abstract--Many robotic systems are comprised of two or more arms. Such systems range from dual-arm household manipula- tors to factory floors populated with a multitude of industrial

  3. 1216 IEEE TRANSACTIONS ON WIRELESS COMMUNICATIONS, VOL. 9, NO. 3, MARCH 2010 Analysis of Area under the

    E-Print Network [OSTI]

    Jiang, Hai

    1216 IEEE TRANSACTIONS ON WIRELESS COMMUNICATIONS, VOL. 9, NO. 3, MARCH 2010 Analysis of Area under improves. However, in the wireless literature, the AUC measure has gone unnoticed. In this paper estimates, the energy detec- tor might enable certain wireless devices to become low-cost. The performance

  4. Neutron Capture Measurements and Resonance Analysis of Dysprosium Y.R. Kang,1

    E-Print Network [OSTI]

    Danon, Yaron

    for control in nuclear reactor [1]. Dysprosium is also a fission product from the thermal fis- sion of 235 U dysprosium's effect on the neutron population over all energy regions in a nuclear reactor system, where Dysprosium has many uses in the field of nuclear reac- tor system due to a very large thermal neutron absorp

  5. February 2013 Green Bulletin

    E-Print Network [OSTI]

    Ishida, Yuko

    Building Out Pests | Page 4 Ask the Expert! | Page 4 New Resources | Page 4 fter decades of relative of two categories: active monitors or passive monitors. Active monitors employ attractants--heat, carbon, especially in the absence of a host, to detect bed bugs that would normally remain hidden. Passive moni- tors

  6. Compulsion Resistant Anonymous Communications

    E-Print Network [OSTI]

    Danezis, George

    of Cambridge, Computer Laboratory, William Gates Building, 15 JJ Thomson Avenue, Cambridge CB3 0FD, United. Chaum in his seminal paper [7] argues that mix networks are secure against a global passive adversary], MorphMix [22] and Tor [15], provide security against a partial passive adversary, that can only

  7. The American Genetic Association 2014.All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

    E-Print Network [OSTI]

    Jones, Adam

    ); and the Centro de Investigaciones Científicas de las Huastecas "Aguazarca," Calnali, Hidalgo, Mexico (Passow, swordtail Individual reproductive success is shaped by a number of fac- tors, including ecological, social, hybridization may impact phe- notypic diversity in traits linked to sperm competitive ability (Joly et al. 1997

  8. OPTIMAL PLACEMENT AND UTILIZATION OF PHASOR MEASUREMENTS FOR STATE ESTIMATION

    E-Print Network [OSTI]

    presents a procedure by which new PMU locations can be systematically determined in order to render measurement unit (PMU). Buses with zero and non- zero injections, and branches with power flow measure- ments- tor based on strictly PMU measurements and investigates the computational performance as well

  9. Low loss liquid crystals for infrared applications Fenglin Penga

    E-Print Network [OSTI]

    Wu, Shin-Tson

    contender for phase modulation, such as spatial light modula- tors (SLMs),[1] laser beam steering,[2,3] adaptive optics, adaptive lenses,[4] and phase shifters in the microwave [5,6] and terahertz [7­9] regions, in which light scattering loss would be intolerable. After having taken this factor of 10

  10. J Geod (2009) 83:335343 DOI 10.1007/s00190-008-0262-5

    E-Print Network [OSTI]

    2009-01-01

    -time earthquake source determination and tsunami warning systems Geoffrey Blewitt · William C. Hammond · Corné · Tsunami · Warning system 1 Introduction As current geodetic techniques approach the ability to moni- tor, GNSS-based systems) that could contribute to real-time earthquake source determi- nation and tsunami

  11. The Second Law of Thermodynamics Chemistry 223

    E-Print Network [OSTI]

    Ronis, David M.

    ) It is impossi- ble to devise an engine operating in a cycle which does work by taking heat from a single heat RE where, E is the Thompson violator, and R is a Carnot refrigerator. If we adjust the sizes of E and R such that all the work is used to run the Carnot refrigera- tor, and view the combined E

  12. Efficient Bulk Deletes in Relational Databases A. Gartner 1

    E-Print Network [OSTI]

    Kemper, Alfons

    , archiving is studied as part of the SAP Terabyte project in cooperation with the University of Passau dramatically in the last couple of years. This trend can be observed even though most database systems have become easier to use and database system administra- tors have gained more and more experience in using

  13. RIS-M-2299 CALCULATION OF DOSE CONSEQUENCES OF A HYPOTHETICAL

    E-Print Network [OSTI]

    , but there is a failure to isolate the containment. This release is represented by the PWR-4 release. The third and cesium decrease by a decade from BWR-2 to PWR-4, and from PWR-4 to BEED, while the release fractions POPULATIONS; IODINE 131; MELTDOWN; PWR TYPE REAC- TORS; RADIATION DOSES; RADIATION HAZARDS; RARE GASES

  14. L1 Data Cache Decomposition for Energy Efficiency Michael Huang, Jose Renau, Seung-Moon Yoo, and Josep Torrellas

    E-Print Network [OSTI]

    Torrellas, Josep

    L1 Data Cache Decomposition for Energy Efficiency Michael Huang, Jose Renau, Seung-Moon Yoo they will have a power density close to a nuclear reac- tor [9]. Reducing the energy consumption of processor on energy-efficient designs for the L1 data cache. It is well known that smaller caches consume less energy

  15. Innovative Applications of O.R. Scheduling electric power production at a wind farm

    E-Print Network [OSTI]

    Kusiak, Andrew

    computations Wind farm Particle swarm optimization Small world network a b s t r a c t We present a model for scheduling power generation at a wind farm, and introduce a particle swarm optimization algorithm) and therefore could be incorporated into an optimization model to assist opera- tors in scheduling wind turbines

  16. Reprinted from: Journal of Systems and Software

    E-Print Network [OSTI]

    Berry, Daniel M.

    positive or negative, write to Robert L. Glass, Edi- tor, Journal of Systems and Software, Computing Trends. The Importance of Ignorance in Requirements Engineering Daniel M. Berry Software Engineering Institute, CarnegieReprinted from: Journal of Systems and Software Volume 28, Number 1 February, 1995 Pages 179

  17. A Study of Central Auction Based Wholesale Electricity Markets

    E-Print Network [OSTI]

    Gatti, Nicola

    authority. In- stead, the distribution of electricity to customers takes part in retail markets. The main electricity markets, called retail market, distribu- tors buy electricity from UP and sell it to customers [6]. Italian and worldwide retails market are not governed by any specific rule. In the scientific community

  18. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Shen, Jun

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : What You Need To Know About High- tors for heart disease. In fact, the higher your blood cholesterol, the greater your risk of developing heart disease or having a heart attack. Heart disease is the #1 killer of men and women in the United

  19. 435,1137128630June2005www.nature.com/nature 0 71486 03070 6

    E-Print Network [OSTI]

    and some other big cities. But such effortshavenotmatchedtheforces of environmental destruction, and have not prevented other indica- tors from further deterioration. The list of problems ranges from air pollution affect China's environment through globalization, pollution and resource exploitation. China is already

  20. THE CHALLENGE IN FINDING LONG-TERM LUBRICATION solutions for wind turbines

    E-Print Network [OSTI]

    Chiao, Jung-Chih

    used a technique known as Simula- tor for Offshore /Onshore Wind Farm Applications to examine wind turbines in a farm in order to improve their longevity. In a previous TLT article, research- ers an existing wind farm and studied five scenarios in which the turbines are spaced in a different manner from

  1. Control of mRNA Export and Translation Termination by Inositol Hexakisphosphate Requires Specific Interaction with Gle1*S

    E-Print Network [OSTI]

    Bedwell, David M.

    Control of mRNA Export and Translation Termination by Inositol Hexakisphosphate Requires Specific of the nuclear pore complex (NPC) is mediated by interactions between soluble mRNA export fac- tors and distinct binding sites on the NPC. At the cytoplasmic side of the NPC, the conserved mRNA export factors Gle1

  2. Perinuclear Mlp proteins downregulate gene expression in response to a defect in mRNA export

    E-Print Network [OSTI]

    Bedwell, David M.

    Perinuclear Mlp proteins downregulate gene expression in response to a defect in mRNA export of Cell Biology, Sciences III, University of Geneva, Geneva, Switzerland The mRNA export adaptor Yra1p/REF contributes to nas- cent mRNP assembly and recruitment of the export recep- tor Mex67p. yra1 mutants exhibit m

  3. The NASA Aura satellite houses four instruments to study atmospheric ozone. The Ozone Monitoring Instrument (OMI) onboard the satellite provides global total column ozone (TCO) and in combination

    E-Print Network [OSTI]

    Thompson, Anne

    iii ABSTRACT The NASA Aura satellite houses four instruments to study atmospheric ozone. The Ozone Monitoring Instrument (OMI) onboard the satellite provides global total column ozone (TCO) and in combination with other instruments tropospheric ozone residual (TOR) can be derived. In this study, the trajectory

  4. Abstract A miniaturized optical set-up based on a CD-ROM player optic was developed for LAPS (light ad-

    E-Print Network [OSTI]

    Moritz, Werner

    device. The lateral res- olution of LAPS measurements can be improved by using GaAs as the semiconductor material instead of Si. The diffusion length of the minority charge carriers was deter- mined to be smaller properties. A map of pH-values in an electrolyte near to an insula- tor surface can be obtained by the light

  5. August 16, 2005 0:31 WSPC/Trim Size: 9in x 6in for Review Volume mvrobust Robust Location and Scatter Estimators in Multivariate

    E-Print Network [OSTI]

    Zuo, Yijun

    and Scatter Estimators in Multivariate Analysis Yijun Zuo Department of Statistics and Probability, Michigan covariance matrix are the cor- ner stone of the classical multivariate analysis. They are optimal when estima- tors and discusses their applications to the multivariate data analysis. 1. Introduction

  6. 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim 1 www.advmat.de

    E-Print Network [OSTI]

    Wang, Zhong L.

    limita- tions of traditional power supplies by providing a supplemen- tary electric power source appliances, such as washing machines and refrigera- tors, to bouncing automobile tires on a gravel road harvesting have been limited to transductions based on piezo- electric effect,[1­5] electromagnetic effect,[6

  7. ORBIT -OPERATING REGIME BASED MODELING AND IDENTIFICATION TOOLKIT

    E-Print Network [OSTI]

    Foss, Bjarne A.

    .A.Johansen@ecy.sintef.no Department of Engineering Cybernetics, The Norwegian University of Science and Technology, N-7034 Trondheim SINTEF Electronics and Cybernetics, Automatic Control Department, N-7034 Trondheim, Norway. Email: Tor and The Norwegian University of Science and Technology have developed a research tool to facilitate further research

  8. STABILIZING LINEAR MPC WITH EFFICIENT PRIORITIZED INFEASIBILITY HANDLING

    E-Print Network [OSTI]

    Foss, Bjarne A.

    Slupphaug Tor Arne Johansen Bjarne A. Foss ;1 Department of Engineering Cybernetics Norwegian University of Science and Technology, Norway Abstract: In order to minimize the number of situations when a model. The fol- 1 Corresponding author, email: Bjarne.Foss@itk.ntnu.no, address: Dept. of Eng. Cybernetics, NTNU

  9. Vacuum 65 (2002) 415425 Plasma spraying of micro-composite thermal barrier coatings

    E-Print Network [OSTI]

    Ghoniem, Nasr M.

    2002-01-01

    blades and vanes of gas turbine engines, turbine shrouds and combus- tor cans. These coatings increase. Keywords: Plasma spraying; Gas tunnel-type; Thermal barrier-composite coatings; Aluminum oxide; ZirconiumVacuum 65 (2002) 415­425 Plasma spraying of micro-composite thermal barrier coatings S. Sharafata

  10. Centerline velocity profile for plain round exhaust hoods 

    E-Print Network [OSTI]

    Martin, Kirksey E

    1977-01-01

    ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ Dal laVal le and Hatch S 1 11verman The Probl em. . . . . . . . . . . . . . . . . . . . . . . . . 10 The Research Hypothesis. . . . . . . . . . . . . . . . . . . 10 METHODOLOGY. . . . . . . . . . . . . . . . . . . . . . . . . . . I 2 DATA ANALYSIS..., System 2, . . . 52 Appendix D ? Statistical Analysis Tables . . . . , . . . , . 63 ITA ~ ~ ~ ~ ~ ~ ~ o o ~ ~ i ~ ~ ~ ~ ~ ~ V ~ ~ ~ Q I ~ ~ 0 Q ~ ~ ~ 66 LIST OF FIBURES Fi gure 1 Air Flow into Simple Hood Page 2 Compound Hood 3 Duct Air Moni tor...

  11. 2730 IEEE TRANSACTIONS ON INDUSTRY APPLICATIONS, VOL. 49, NO. 6, NOVEMBER/DECEMBER 2013 A Novel Soft-Switching Bidirectional DCDC

    E-Print Network [OSTI]

    Mi, Chunting "Chris"

    areas, such as appliances, general industries, and aerospace, which include uninterruptible power circuit, which consists of a half-bridge power switch, an inductor, and capaci- tors. In order to realize, resonant power converter, zero-voltage switching (ZVS). I. INTRODUCTION BIDIRECTIONAL dc­dc converters can

  12. C. R. Acad. Sci. Paris, Ser. I 342 (2006) 2328 http://france.elsevier.com/direct/CRASS1/

    E-Print Network [OSTI]

    Porretta, Alessio

    2006-01-01

    . Paris, Ser. I 342 (2006). 2005 Académie des sciences. Published by Elsevier SAS. All rights reserved sciences. Published by Elsevier SAS. All rights reserved. doi:10.1016/j.crma.2005.09.027 #12;24 N. Grenon, Università di Roma Tor Vergata, Via della Ricerca Scientifica 1, 00133 Roma, Italy Received 31 August 2005

  13. Lyapunov-based Optimizing Control of Nonlinear Blending Process

    E-Print Network [OSTI]

    Johansen, Tor Arne

    1 Lyapunov-based Optimizing Control of Nonlinear Blending Process Tor A. Johansen£ , Daniel Sb processes consisting of linear dynamics and a static nonlinearity are considered. We propose a control law that optimizes the equilibrium point of the process and regulates the output to the corresponding equilibrium

  14. Lyapunov-based Optimizing Control of Nonlinear Blending Processes

    E-Print Network [OSTI]

    Johansen, Tor Arne

    1 Lyapunov-based Optimizing Control of Nonlinear Blending Processes Tor A. Johansen , Daniel Sb processes consisting of linear dynamics and a static nonlinearity are considered. We propose a control law that optimizes the equilibrium point of the process and regulates the output to the corresponding equilibrium

  15. TRACE FORMULAS AND BORGTYPE THEOREMS FOR MATRIXVALUED JACOBI AND DIRAC

    E-Print Network [OSTI]

    TRACE FORMULAS AND BORG­TYPE THEOREMS FOR MATRIX­VALUED JACOBI AND DIRAC FINITE DIFFERENCE­valued Jacobi opera­ tors H and supersymmetric Dirac di#erence operators D are proved. More precisely, assuming reflectionless matrix coe#cients A, B in the self­adjoint Jacobi operator H = AS + + A - S - + B (with

  16. nature genetics volume 24 march 2000 257 Evidence for gene transfer and expression of factor IX

    E-Print Network [OSTI]

    Kay, Mark A.

    circulating levels of F.IX and frequency of F.IX protein infusion. The evidence of gene expression at low­5% of normal generally have a more moderate course. Current treatment is based on intravenous infusion of clotting factor concentrates; regimens in which fac- tor is infused prophylactically, with a goal

  17. Gait Evolution for a Hexapod Robot Karen Larochelle, Sarah Dashnaw, and Gary Parker

    E-Print Network [OSTI]

    Parker, Gary B.

    Gait Evolution for a Hexapod Robot Karen Larochelle, Sarah Dashnaw, and Gary Parker Computer (simultaneous commands to the leg actua- tors) for hexapod gaits has been done using Cyclic Ge- netic Algorithms with measured rates for all possible leg movements to generate gaits for a hexapod robot. These gaits

  18. Computation of Lyapunov Functions for Smooth Nonlinear Systems using Convex Optimization

    E-Print Network [OSTI]

    Johansen, Tor Arne

    Computation of Lyapunov Functions for Smooth Nonlinear Systems using Convex Optimization Tor A that for smooth nonlinear systems conditions for the existence of a Lyapunov function that guarantees uniform assuming a general linearly parameterized class of smooth non­quadratic Lyapunov­function candidates. Hence

  19. FFAGS FOR MUON ACCELERATION J. Scott Berg, Stephen Kahn, Robert Palmer, Dejan Trbojevic,

    E-Print Network [OSTI]

    Keil, Eberhard

    the desired energy gain. An alter- native method for muon acceleration is using a fixed field alternating gradient (FFAG) accelerator. Such an accelera- tor has a very large energy acceptance (a factor of two with time. The arc must be able to transmit a beam over a wide range of energies. The first difficulty

  20. EU FP7 Project Grant Agreement 317761

    E-Print Network [OSTI]

    Tronci, Enrico

    Intelligent Automation Services computing a safe energy price policy for each home (global electric grid Transfer Insti- tute of the National Academy of Sciences of Belarus (Belarus) ATANVO GmbH (Germany economic value to Distribution System Opera- tors (DSOs) by optimising electric network operation through

  1. Automating Dynamic Decoupling in Object-Oriented Modelling and Simulation Tools

    E-Print Network [OSTI]

    Como, Giacomo

    a Modelica transla- tor. Simulation tests demonstrate the technique, and the re- alised implementation than of simulation theory. In this work we refer as "EOO Modelling Tool" to a Modelica translator, to allow exemplifying the (more general) presented ideas. For a Modelica translator, the EOO modelling

  2. Topic-Based Audience Metrics for Internet Marketing by Combining Ontologies and Output Page Mining

    E-Print Network [OSTI]

    Libre de Bruxelles, Université

    designers and Web de- velopers [19]. Summary reports like the number of visi- tors and the number of page metrics which should represent the Web site topics. Finally, we validate our approach with experiments by a FNRS Research Fel- low Grant. has most emerged in the corporate world. Web analytics fo- cuses

  3. Original Articles In Vitro Evaluation of Multiobjective Hemodynamic Control

    E-Print Network [OSTI]

    Antaki, James F.

    Lake City, UT). To avoid the need for flow sensors, a state estima- tor was used, based on the back-EMF. In the absence of sensors to directly detect the immi- nence of suction or the hemodynamic load, we have intro

  4. NONLINEAR FINITE ELEMENT ANALYSIS OF REINFORCED CONCRETE STRUCTURES SUBJECTED TO TRANSIENT THERMAL LOADS

    E-Print Network [OSTI]

    Vecchio, Frank J.

    Abstract ii NONLINEAR FINITE ELEMENT ANALYSIS OF REINFORCED CONCRETE STRUCTURES SUBJECTED nonlinear finite element transient thermal analysis is implemented into program VecTor2©, a nonlinear's response to thermal loads, this research develops and implements a 2D nonlinear finite element transient

  5. Evaluating High Efficiency Motor Retrofit 

    E-Print Network [OSTI]

    Evans, T. A.

    1984-01-01

    .rinqs tor lllalor L...i6e ? Rwre """ PQ'IftlWta ; $6....2: On........ e..... Ro. ~ t;:j'.o ? 8.-3 ??-111'" r; AAGIr ? 4.QQQ 10 l5000 ~Y... 0peq1::Ign FIGURE 24 546 AuumptioM ? Power Coet: ? Pow.,. e-t Inflation: .P~Ufe: ? S"IIQ. Yalue: ? La...

  6. HUMAN GENE THERAPY 16:299306 (March 2005) Mary Ann Liebert, Inc.

    E-Print Network [OSTI]

    Kay, Mark A.

    HUMAN GENE THERAPY 16:299­306 (March 2005) © Mary Ann Liebert, Inc. Modified Infusion Procedures expression was equal with hepatic artery and portal vein infusion, which was higher than vector administered via peripheral venous infusion. Next, we determined how localized perfusion or changing the vec- tor

  7. Biomech Model Mechanobiol (2009) 8:285299 DOI 10.1007/s10237-008-0135-0

    E-Print Network [OSTI]

    Ortiz, Michael

    2009-01-01

    , the repetition rate, and the voltage (or energy) of the shock wave genera- tor. The latter is directly associated damage in extracorporeal shock wave lithotripsy: a numerical approach for different shock profiles September 2008 © Springer-Verlag 2008 Abstract In shock-wave lithotripsy--a medical procedure to fragment

  8. A Cascade Method for Reducing Training Time and the Number of Support Vectors

    E-Print Network [OSTI]

    Lu, Bao-Liang

    subproblems and to parallelly learn these subproblems by many modules. After training, all the trained modulesA Cascade Method for Reducing Training Time and the Number of Support Vectors Yi-Min Wen1,2 and Bao 400052, China Abstract. A novel cascade learning strategy for training support vec- tor machines (SVMs

  9. Our Economic Impact: on the City of Birmingham and West Midlands Region

    E-Print Network [OSTI]

    Birmingham, University of

    Our Economic Impact: on the City of Birmingham and West Midlands Region #12;2 Economic Impact Report The University of Birmingham has a major economic impact on the region as: The full Oxford Economics report can be found at www.birmingham.ac.uk/economic-impact an edUcaTor The University attracts

  10. 76 PERVASIVE computing Published by the IEEE CS n 1536-1268/14/$31.00 2014 IEEE Smartphones Editor: Roy Want n Google n roywant@acm.org

    E-Print Network [OSTI]

    Cortes, Corinna

    to power monitoring in the mobile design process, either when building mobile hardware or writing software of these devices--that is, the power consumption resulting from transis- tors switching on and off, because computers from static desktop computers--low-power operation, wireless networking, mobile sensing, low

  11. Scattering E#ects in the TESLA Colllimation Adriana Bungau

    E-Print Network [OSTI]

    Scattering E#ects in the TESLA Colllimation System Adriana Bungau University of Manchester scattering angles and random output direction. In the TESLA TDR simulations, the collimation depth was set of the particles which strike the TESLA collima­ tors can not be possible without taking into consideration

  12. Frequent recombination and low level of clonality within Salmonella enterica subspecies I

    E-Print Network [OSTI]

    Lan, Ruiting

    Frequent recombination and low level of clonality within Salmonella enterica subspecies I Sophie of Salmonella enterica subspecies I strains were analysed using nucleotide sequences of four genes (mglA, proV, torC and speC). Fifteen strains from the Salmonella reference collection B (SARB), belonging to 13

  13. Cold neutron prompt gamma activation analysis, a non-destructive technique for hydrogen level assessment in zirconium alloys

    E-Print Network [OSTI]

    Motta, Arthur T.

    assessment in zirconium alloys Adrien Couet a, , Arthur T. Motta a , Robert J. Comstock b , Rick L. Paul c to quantitatively assess hydrogen concentration in zirconium alloys. The technique, called Cold Neutron Prompt Gamma. Introduction With increased burnups and longer life times in nuclear reac- tors, uniform corrosion of zirconium

  14. NATURE METHODS | VOL.2 NO.3 | MARCH 2005 | 225 TECHNOLOGY FEATURE

    E-Print Network [OSTI]

    Cai, Long

    by a number of companies is based on fluorescence resonance energy transfer (FRET)-- a detection method inhibi- tor. It is no surprise then that academic labs and pharmaceutical companies are hot on the trail companies offer reagents for these tests, including off-the-shelf and custom-made kinase kits

  15. Transcription Factor IID Recruitment and Sp1 Activation DUAL FUNCTION OF TAF1 IN CYCLIN D1 TRANSCRIPTION*

    E-Print Network [OSTI]

    Wang, Edith

    kinases, an event necessary to drive cells through the proliferation cycle (1). Cyclin protein levels-7280 Cyclin D1 is an oncogene that regulates progression through the G1 phase of the cell cycle. A temperature to arrest in late G1 by decreasing transcription of cell cycle regula- tors, including cyclin D1. Here we

  16. GEOPHYSICS, VOL. 70, NO. 4 (JULY-AUGUST 2005); P. D29D36, 6 FIGS., 1 TABLE. 10.1190/1.1993708

    E-Print Network [OSTI]

    van der Baan, Mirko

    they allow us to record the com- plete elastic wavefield without the need to employ expensive and often-mail: mvdbaan@earth.leeds.ac.uk. c 2005 Society of Exploration Geophysicists. All rights reserved-SV reflections need to be identified in order to interpret the data). The issue of vec- tor fidelity is related

  17. A Refined Examination of the Facial Cues Contributing to Vicarious Effects on Self-Pain and Spinal Responses

    E-Print Network [OSTI]

    Gosselin, Frédéric

    -eight normal volunteers received electrical stimulation of the sural nerve immediately after they viewed (NFR) evoked by the shock were recorded. Results show that diagnostic stimuli lead to higher subjective reactions. Many fac- tors have been shown to influence the interpretation of the bottom-up signal

  18. Ontological resources and question answering Roberto Basili (*), Dorte H. Hansen (**),Patrizia Paggio (**),

    E-Print Network [OSTI]

    Ontological resources and question answering Roberto Basili (*), Dorte H. Hansen (**),Patrizia Produzione University of Rome "Tor Vergata" {basili,pazienza,zanzotto} @info.uniroma2.it (**) Centre- tions (Voorhees 2001)), are able both to understand questions in natural language and to produce answers

  19. Open Domain Information Extraction via Automatic Semantic Labeling Alessandro Moschitti

    E-Print Network [OSTI]

    Moschitti, Alessandro

    of Computer Science Systems and Production University of Rome Tor Vergata 00133 Rome (Italy) moschitti@info by the labels are generated auto- matically with a high precision. Keywords: Natural Language Processing of automatically identifying information of interest from the vast Internet resources is by employing Information

  20. Perceived challenges to public health in Central and Eastern Europe: a qualitative analysis

    E-Print Network [OSTI]

    Müller-Nordhorn, Jacqueline; Holmberg, Christine; Dokova, Klara G.; Milevska-Kostova, Neda; Chicin, Gratiana; Ulrichs, Timo; Rechel, Bernd; Willich, Stefan N.; Powles, John; Tinnemann, Peter

    2012-04-26

    Open Access ublic health in Central litative analysis G Dokova3, Neda Milevska-Kostova4, Gratiana Chicin5, s8 and Peter Tinnemann1 between Central and Eastern Europe compared to tors are amenable to public health interventions. Thed Central Ltd...

  1. Gate-Dependent Carrier Diffusion Length in Lead Selenide Quantum Dot Field-Effect Transistors

    E-Print Network [OSTI]

    Yu, Dong

    - generation photovoltaic devices and sensitive photodetec- tors.1-3 The potential for low fabrication cost investigated for their potential use in novel electronic devices. Of particular interest is their use in third using scalable manufacturing processes such as ink jet printing make them attractive candidates for next-generation

  2. Harry Gray and Mr. Sun en-joy each others' company.

    E-Print Network [OSTI]

    Faraon, Andrei

    're generated cleanly, and the beSt way to do that in the long term is by nuclear fusion. I'll be over- joyed to harvest it. The third is catalysis-dle efficient making and breaking of chemical bonds usi ng- tors-photovoltaics such as silicon that convert sunlight into electricity. We now have durable silicon

  3. s Less than 40 nanoseconds rms accuracy to UTC during Selective Availability (SA)*

    E-Print Network [OSTI]

    Berns, Hans-Gerd

    ® s Less than 40 nanoseconds rms accuracy to UTC during Selective Availability (SA)* s Better than and frequency accuracy available in a GPS timing receiver. Standard outputs include a 1 PPS, analog IRIG B time to UTC even during Selective Availability (SA). This superior oscilla- tor disciplining to GPS enables

  4. Cell competition: Winning out by losing notch

    E-Print Network [OSTI]

    Alcolea, Maria P.; Jones, Philip H.

    2015-01-20

    SE, Mail- lard I, Pear WS. Notch signaling is an important regula- tor of type 2 immunity. J Exp Med 2005; 202:1037-42; PMID:16230473; http://dx.doi.org/10.1084/jem. 20050923 54. Shih HP, Kopp JL, Sandhu M, Dubois CL, Seymour PA, Grapin-Botton A...

  5. The ITRS Design Technology and System Drivers Roadmap: Process and Status

    E-Print Network [OSTI]

    Kahng, Andrew B.

    The ITRS Design Technology and System Drivers Roadmap: Process and Status Andrew B. Kahng CSE (TWG) is one of 16 working groups in the International Technology Roadmap for Semiconduc- tors (ITRS) effort. It is responsible for the ITRS' Design Chap- ter, which roadmaps design technology requirements

  6. ITRS 2.0: Toward a Re-Framing of the Semiconductor Technology Roadmap

    E-Print Network [OSTI]

    Kahng, Andrew B.

    ITRS 2.0: Toward a Re-Framing of the Semiconductor Technology Roadmap Juan-Antonio Carballo3, Wei@ucsd.edu Abstract--The International Technology Roadmap for Semiconduc- tors (ITRS) has roadmapped technology requirements of the semiconductor industry over the past two decades. The roadmap identifies major challenges

  7. 56 N U C L E A R N E W S April 2009 N DE C E M B E R 2, 2008--the

    E-Print Network [OSTI]

    Kemner, Ken

    Sattelberger, Energy Sciences and Engineering Associate Laboratory Direc- tor, led the renovation sus- tained nuclear chain reaction--a revived Nuclear Energy Exhibit was offi- cially opened to the Nuclear Energy Exhibit at Argonne National Laboratory can view artifacts dating back to the start

  8. Nondestructive characterization of a TiN metal gate: Chemical and structural properties by means of standing-wave hard x-ray

    E-Print Network [OSTI]

    Fadley, Charles

    N, it is used as a protective coating on metals, including tools used for surgery and vari- ous high speed cutting applications. For instance, TiN coat- ings with thicknesses of about 2­10 lm are generally found to increase tool life by several hundred per cent.1 TiN also has important applications in the semiconduc- tor

  9. 1 INTRODUCTION: COHERENT STATES FOR CHEMICAL SIMULATIONS

    E-Print Network [OSTI]

    Morales, Jorge Alberto

    be treated via classical mechanics with added quantum corrections on top (Miller 2001). Conversely, regions, PP involves (Klauder & Skagerstam 1985): (1) finding adequate sets of Lie-algebra generators [here, the Weyl algebra creation (annihilation) a ( a ) opera- tors] and then (2) applying an associated Lie

  10. In Handbook of Virtual Humans, N. Magnenat-Thalmann and D. Thalmann (Eds.), John Wiley & Sons, UK, 2004, 303-322

    E-Print Network [OSTI]

    Kallmann, Marcelo

    to real-time animation of virtual human ac- tors, the ability to interact with virtual objects requiresIn Handbook of Virtual Humans, N. Magnenat-Thalmann and D. Thalmann (Eds.), John Wiley & Sons, UK and robotics techniques. It is still a challenge to animate a virtual actor that can decide its motions

  11. OBJECT TRACKING IN AERIAL VIDEO OF SMOKY ENVIRONMENTS

    E-Print Network [OSTI]

    objects in video of smoky regions provided by unmanned aerial vehicles. Such moving objects may include Detection, Neural Networks, Support Vec- tor Machines. 1 Introduction Unmanned aerial vehicles (UAV be raised automatically when an individual is presumed to be in harm's way. Keywords: Unmanned Aerial

  12. Workshop on Visualisation in Environmental Sciences (EnvirVis) (2015) A. Middel, G. Weber, and K. Rink (Editors)

    E-Print Network [OSTI]

    Maciejewski, Ross

    2015-01-01

    scarcity, un- derstanding the links between water scarcity and other sec- tors (such as energy, economy, we present a case study which explores the potential impact that the China south-north water transportation project in the Yangtze River basin will have on projected water demands. Categories and Subject

  13. The North Pacific subtropical gyre is a large oceanic gyre bounded on

    E-Print Network [OSTI]

    Hawai'i at Manoa, University of

    /index.php) to investigate whether the ecosystem contained any keystone species (Kitchell et al., 1999; 2002). The results indicated that there was not any single species group that func- tioned as a keystone, but that a broad; 2002). In effect, the fishing fleet is the keystone preda- tor (Kitchell et al., 1999). However another

  14. Concurrent Signature without Random Oracles , Qiong Huang2

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    an extra secret called key- stone is released by A. Once the keystone is released, A and B will become. Instead, the initia- tor A and the matcher B interact in the following three phases: (1) Keystone Generation Phase: A generates a keystone s and the corresponding keystone fix f, and sends f to B; (2

  15. Environmental Review A Monthly Newsletter of Environmental Science and Politics

    E-Print Network [OSTI]

    Twelve Sea Otters As Keystone Predators Introduction: Sea otters in the North Pacific were hunted. Sea otters are called keystone preda- tors because they exert a disproportionally large effect otters as keystone predators, their overall recovery and recent setbacks in the Aleutian Islands. ER

  16. Inside this issue: CAFNRM Congratulates 25 Graduating Ag

    E-Print Network [OSTI]

    Wiegner, Tracy N.

    of the GMO corn. The dairy attempted to find seed that was not GMO and still adapted to the local climatic and soil fac- tors. A non-GMO seed source was found but when the monetary and environmental costs and found to be undesirable for use on the dairy. The GMO hybrids made more sense both economically

  17. alternative explanations are necessary to accommodate all the available data. A num-

    E-Print Network [OSTI]

    1686 alternative explanations are necessary to accommodate all the available data. A num- ber the mitochondrial p53 could function as an enabler BH3-only protein to release activa- tors like Bid (see the figure and Bid, also display this activity. Because PUMA has an extremely high affinity for the anti- apoptotic

  18. Wireless Sensing, Actuation and Control --with Applications to Civil Structures

    E-Print Network [OSTI]

    Lynch, Jerome P.

    the safety of civil structures, including buildings, bridges, dams, tunnels, and others, is of utmost and controllers. Active control systems use a small number of large mass dampers or hydraulic actua- tors- active hydraulic dampers (SHD), electrorheological (ER) and magnetorheological (MR) dampers. Semi

  19. Open Archive TOULOUSE Archive Ouverte (OATAO) OATAO is an open access repository that collects the work of Toulouse researchers and

    E-Print Network [OSTI]

    Boyer, Edmond

    for capacitive storage devices. We demonstrate the efficacy of these electrodes in a hybrid electrochemical cell pervasive, the use of electrochemical capaci- tors (ECs) as electrical energy storage devices is finding of Nanostructured Nb2O5 Electrodes. (2014) Journal of The Electrochemical Society (JES), vol. 161 (n° 5). pp. A718-A

  20. Um cientista universitrio

    E-Print Network [OSTI]

    Instituto de Sistemas e Robotica

    contributo fun- damental para impedir que Portugal entrasse no beco sem saída da energia nuclear, sec- tor militante quebraram o consenso per- verso que estava a construir- se após 1 974, a favor do nuclear

  1. Downloaded 16 Dec 2009 to 128.83.61.179. Redistribution subject to AIP license or copyright; see http://pop.aip.org/pop/copyright.jsp Wave energy flow conservation for propagation in inhomogeneous Vlasov-

    E-Print Network [OSTI]

    Morrison, Philip J.,

    http://pop.aip.org/pop/copyright.jsp Wave energy flow conservation for propagation in inhomogeneous are thereby obtained. I. INTRODUCTION In the Vlasov-Maxwell theory, wave energy conserva- tion is commonly to examine the conservation of wave energy flow for Hermitian opera- tors. Such operators satisfy relations

  2. Generating stationary entangled states in superconducting qubits Jing Zhang,1,2,* Yu-xi Liu,1,3

    E-Print Network [OSTI]

    Nori, Franco

    of Physical and Chemical Research (RIKEN), Wako-shi, Saitama 351-0198, Japan 2 Department of Automation- tor 23 , or a transmission line resonator 24­26 . The main merit of indirect coupling is that any two production strategies 29­31 . Most of the proposed stationary entangle- ment production strategies utilize

  3. Dynamic Positioning System as Dynamic Energy Storage on Diesel-Electric Ships

    E-Print Network [OSTI]

    Johansen, Tor Arne

    1 Dynamic Positioning System as Dynamic Energy Storage on Diesel-Electric Ships Tor A. Johansen in order to implement energy storage in the kinetic and potential energy of the ship motion using the DP in order to relate the dynamic energy storage capacity to the maximum allowed ship position deviation

  4. What do SST proxies really tell us? A high-resolution multiproxy 86 and foraminifera d18

    E-Print Network [OSTI]

    Gilli, Adrian

    ). Potential contribu- tors to the global LIA cooling were a lowering in total solar irradiance (e.g., Eddy century global warming. This period includes the Little Ice Age (LIA), which is the most recent period solar activity, associated with an increase in climate variability in Europe (Luterbacher et al., 2001

  5. High-Energy Physics on DECPeRLe-1 Programmable Active Memory

    E-Print Network [OSTI]

    Vuillemin, Jean

    Research Laboratory, Rueil- Malmaison, France. 1European Organization for Nuclear Research, Geneva: The ATLAS experiment. of the century, around year 2002. Two dierent detec- tor sets are being designed: CMS discrimination based on physics criteria. The third-level trigger is composed of high-level processors

  6. Identification of 13-Hydroxy-14,15-epoxyeicosatrienoic Acid as an Acid-stable Endothelium-derived Hyperpolarizing

    E-Print Network [OSTI]

    Hammock, Bruce D.

    Identification of 13-Hydroxy-14,15-epoxyeicosatrienoic Acid as an Acid-stable Endothelium-derived and vasoconstric- tor autacoids. Two of the well-defined endothelium-derived vasodilators are prostacyclin (PGI2, this third factor is termed endothelium-derived hyperpo- larizing factor (EDHF) (7­10). Unlike PGI2 and NO

  7. RF Power Generation in LINAC4

    E-Print Network [OSTI]

    Brunner, O; Schwerg, J N

    2010-01-01

    Linac4 is a lin­ear ac­cel­er­a­tor for neg­a­tive Hy­dro­gen ions (H-) which will re­place the old Linac2 as lin­ear in­jec­tor for the CERN ac­cel­er­a­tors. Its high­er en­er­gy of 160 MeV will give in­creased beam in­ten­si­ty in the down­stream ma­chines. Linac4 is about 100 m long, nor­mal-con­duct­ing, and will be housed in a tun­nel about 12 m below ground. The Linac4 tun­nel will be con­nect­ed to the ex­ist­ing chain of ac­cel­er­a­tors and can be ex­tend­ed to the new in­jec­tion chain. The high RF power for the Linac4 ac­cel­er­at­ing struc­tures will be gen­er­at­ed by thir­teen 1.3 MW klystrons, pre­vi­ous­ly used for the CERN LEP ac­cel­er­a­tor, and six new 2.8 MW klystrons of all op­er­at­ing at a fre­quen­cy of 352.2 MHz. The in­te­gra­tion of the RF power sys­tem in the build­ing is pre­sent­ed. The tech­ni­cal spec­i­fi­ca­tions and the per­for­mance of the var­i­ous high-pow­er el­e­ments are dis­cussed, ...

  8. USDOE Top-of-Rail Lubricant Project

    SciTech Connect (OSTI)

    Mohumad F. Alzoubi; George R. Fenske; Robert A. Erck; Amrit S. Boparai

    2002-02-01

    Lubrication of wheel/rail systems has been recognized for the last two decades as a very important issue for railroads. Energy savings and less friction and wear can be realized if a lubricant can be used at the wheel/rail interface. On the other hand, adverse influences are seen in operating and wear conditions if improper or excessive lubrication is used. Also, inefficiencies in lubrication need to be avoided for economic and environmental reasons. The top-of-rail (TOR) lubricant concept was developed by Texaco Corporation to lubricate wheels and rails effectively and efficiently. Tranergy Corporation has been developing its SENTRAEN 2000{trademark} lubrication system for the last ten years, and this revolutionary new high-tech on-board rail lubrication system promises to dramatically improve the energy efficiency, performance, safety, and track environment of railroads. The system is fully computer-controlled and ensures that all of the lubricant is consumed as the end of the train passes. Lubricant quantity dispensed is a function of grade, speed, curve, and axle load. Tranergy also has its LA4000{trademark} wheel and rail simulator, a lubrication and traction testing apparatus. The primary task of this project was collecting and analyzing the volatile and semivolatile compounds produced as the lubricant was used. The volatile organic compounds were collected by Carbotrap cartridges and analyzed by adsorption and gas chromatography/mass spectrometry (GC/MS). The semivolatile fraction was obtained by collecting liquid that dripped from the test wheel. The collected material was also analyzed by GC/MS. Both of these analyses were qualitative. The results indicated that in the volatile fraction, the only compounds on the Environmental Protection Agency's (EPA) Superfund List of Analytes detected were contaminants either in the room air or from other potential contamination sources in the laboratory. Similarly, in the semivolatile fraction none of the detected compounds are on the EPA's Superfund List of Analytes. The major compound in the semivolatile fraction is 1,2-propanediol, which was also found as the major component of the TOR lubricant before testing. Other compounds found in trace quantities either were present in the TOR lubricant or were small fragments from the polymeric component of the TOR lubricant. The second task for Argonne in this project was to investigate the effects of axle load, angle of attack, and quantity of lubricant on lateral friction forces, as well as the consumption time of the TOR lubricant. The second task was to collect and qualitatively identify any volatile and semivolatile compounds produced upon use of the TOR lubricant.

  9. The World of Dark Shadows Issue 13 

    E-Print Network [OSTI]

    Multiple Contributors

    1977-01-01

    wasn' t asking tor my hea l th. Again, I' m sorry. his issue, in hODor of tihadovCoD, is 6 pages lonJ:,er than regulerly. I just coul dn' t fit everything in in lesa. Next issue wi ll bsve convention report s. Next issue, tor al l or you who only... sew ~) on t he reruns snd are thoroughly contused, WI l l contain a general Db pl ot summary Bill Hunt has suggested 3 D3 rsn d ir~cuory--a l ist i nb ot • f an s by the state in wbich thay live. I f you would- -or would not-­ like 1;0 be listed, let...

  10. The World of Dark Shadows Issue 4 

    E-Print Network [OSTI]

    Multiple Contributors

    1976-01-01

    ..de on Ka110,·. body I Roger w.a waitio~ tor the coroner 8 report on bow he died. Rogar took Vicki on a tour at thll cannery and tblll etopped olt at the Sberitt'e ott1cII tor II tew minut88. Hogor wanted ber to corroborate hia atory tbat he lett...1';;:;' her ba,ru.'.J"tJ. ~:.~ 1/0:r::l 8 r;;bc. £:::'::1 b~c.ra 0 £:"U;lU uut!:iae her ,.,i:l~c~l. 8be 1;)':>~5 -: ... '.o'l:rd tt:e l'Iir.ticw, aoes a il.i.T. :'::0 t;R5?S. ':':.,0: bl:'; :1i5C9P:U' :i. :::.lj -::".1:-:•.:. ~ael. :(. tit: dr...

  11. The World of Dark Shadows Issue 5 

    E-Print Network [OSTI]

    Multiple Contributors

    1976-01-01

    AUTHORI ZED REPRINT THE -f~~ vJORlD \\ 4\\ · " . OF SHADOWS I. ,' l :: WORLD Cr ~ARlC 8H~DOI48 f i~O. 19'76. · 1Jl&l.DI raD i u. JriOi'i11. 11.00 a1D1ti labl, ,Co. 50 tor thn'l 15.00 tor liz. 'r08 lCatb,7 Rucb, 42} 8pr1q St •• KiapeD, U..., Chic.go, Boaton and Pbilad.lpl!ia. . , ' Worldvision tri.d to aell -Sh.dov." in 1971 after it lett tbe web leh.dule, but DOt .nough .tetioDa vera th.n intera.te4 to cov.r ~he re.idual nut. «Firet expl.netion 8a ·to vhy DB v.s n.v.r .,ndloated b...

  12. Pinch Technology-Theory into Practice 

    E-Print Network [OSTI]

    Saboo, A.; Craw, I.; Hindmarsh, E.; Boland, D.

    1986-01-01

    (on-plant utiliz tion or export) o Effective Utilization of Waste Heat tors are selected on the basis of the power and hea The most suitable type of power gener demand of the process. The profile matching proc dure for integrating of the heat.... CHP System Interaction CHP analysis indicates that after implementation of low temperature heat recovery schemes in the power station and other plants, there will be a net surplus of LP steam. Efforts should be made to generate intermediate...

  13. Theatre Seasons and Festivals

    E-Print Network [OSTI]

    1969-10-01

    desarrollo; a la vez que su función en escala nacional, cosas estas que fueron tomadas como pretexto para enfrentar el funcionamiento actual del Centro Venezolano de Teatro y lo que debe ser su verdadero papel en cuanto entidad comprometida con todo el... tituido por 3 personas: Eduardo Moreno, Armando Gota, Miguel Tor- rence. 13. Incorporar a la Asociación Venezolana de Periodistas, en escala nacional, al Centro Venezolano de Teatro. 14. Promover un curso de Dirección Teatral con la participación de...

  14. What could infant and young child nutrition learn from sweatshops?

    E-Print Network [OSTI]

    Singer, Peter A; Ansett, Sean; Sagoe-Moses, Isabella

    2011-05-05

    Vitamin A, iron, zinc), essential fats, and energy. Therefore, ade- quate Infant and Young Child Nutrition (IYCN) demands high rates of breastfeeding and good access to nutrient rich complementary foods, requiring public sec- tor action to promote... feeding are diminished with reliable access to Singer et al. BMC Public Health 2011, 11:276 http://www.biomedcentral.com/1471-2458/11/276 Page 2 of 5 clean water. Moreover, the companies claim the Code has shortcomings: it is open to interpretation...

  15. Major Oak Diseases and Their Control. 

    E-Print Network [OSTI]

    Johnson, Jerral D.; Appel, David N.

    1984-01-01

    in many areas where oaks are the predominant native tree species. Research shows that much of this mortality is due to disease-causing organisms or disease complexes 10- volving environmental stress and pathogens. FOLIAR DISEASES Anthracnose (Fungus... tor nado, hurricane, severe hail or following a period of mechanical activity around oak trees. Heavy equip- ment working around trees can create large wounds. When this occurs, insects are attracted to the site and may be carrying the wilt...

  16. Effect of hyperlipidemic diets on follicular steroidogenesis and development in Brahman crossbred females 

    E-Print Network [OSTI]

    Wehrman, Michael Eugene

    1990-01-01

    I REVIEW OF LITERATURE Effects of Lipoproteins on Steroidogenesis . . Lipoproteins Lipoprotein Influence on Steroidogenesis . . Follicular Fluid Lipoproteins, . . . . . . . . . . . . LDL-Receptor HDL-Receptor Ovarian Follicular Development... by increasing lipoprotein-associated choles- terol available for entering the steroidogenic pathway. LDDL-Ra e tor. Ilet lute 1 cells So short-t tt e hs e h shown to possess specific receptors for LDL and HDL (Rajendran, 1983). In addition, Brown...

  17. ARTS & SCIENCES Jezebel's Lipstick

    E-Print Network [OSTI]

    Gilchrist, James F.

    TriBUTOrs EDiTOr Robert Nichols CAs ADVisOrY BOArD Donald E. Hall, dean Frank Davis, Diane Hyland, Garth Isaak.A. Richard Laliberte Tricia Long '12G Robert Nichols Esther Shanahan pHOTOgrApHErs Dan Addison Daria Amato, associate deans DEsignEr Kayley LeFaiver COnTriBUTing WriTErs Jack Croft Leslie Feldman Geoff Gehman, '89 M

  18. Morphological and molecular changes in the murine placenta exposed to normobaric hypoxia throughout pregnancy

    E-Print Network [OSTI]

    Mattheson, Hannah; Veerbeek, Jan H. W.; Charnock-Jones, D. Stephen; Burton, Graham J.; Yung, Hong Wa

    2015-08-11

    by a selective arrest of translation mediated principally through phosphorylation of eukaryotic initiation factor eIF2? (Koritzinsky et al., 2006; Fahling, 2009). In the longer term, changes in AKT-mTOR signalling effect metabolic, angiogenic, anti... under adverse conditions may be a risky approach by the male fetus that could result in higher embryonic lethality. Oxygen crosses the placenta by simple diffusion, and the principal driving force is the concentration gradient between the two...

  19. 2. Od Scheme ke Common Lispu Studijni cile: !elem tto !sti je poskytnout u"ivatel#m jazyka Scheme prvn infor-

    E-Print Network [OSTI]

    Krupka, Michal

    . Za!ínající programátor v Common Lispu se pohybuje roz- sáhl'm a nep$ehledn'm terénem, ve kterém se z°uvodce studiem Nep$esnost ve vyjad$ování vede k nep$esnosti sd&lení. Nep$esné pochopení zá- klad# mívá v

  20. Versatile Applications of Nanostructured Metal Oxides

    E-Print Network [OSTI]

    Li, Li

    2014-05-29

    of nanopar- ticles becomes broader, an onion type morphology was observed, particles larger than RPEO segregate out, forming a silica-rich core surrounded by a lamellar or lamel- lar/hexagonal structure. This can be understood by the entropic contributions... , acids or bases, metal salts, enzymes, radical initia- tors and solvents. Heterogeneous catalysts typically are solids that do not dissolve. For example, supported metals, transition metal oxides and sulfides, solid acids and bases, immobilized enzymes...

  1. Environment Affects Market Value of Eggs. 

    E-Print Network [OSTI]

    Allen, William S.; Schlamb, Kermit F.; Beanblossom, Floyd Z.

    1955-01-01

    . Since time, temperature and humidity affect these fac- tors as well as weight, favorable environment is highly irn- 1 portant from the time eggs are laid until used. I I The California Agricultural Experiment Station reports , that albumen quality... and absorb odors readily when close to or held in cooler with other products having strong odors such as onions and kerosene. Careful consideration should be given as to where eggs are to be kept. Unfavor- able results from such surroundings usually...

  2. Men near a Train 

    E-Print Network [OSTI]

    Unknown

    2011-09-05

    volume commitments from the shipper in exchange for lower rates. Railroads are able to reduce operating costs through multi ple-car, point-to-point grain movements. Multicar shipments generally expedite equipment han dling, shorten equipment... of making multiple car load shipments for which significant rate reduc tions are offered. Most contract arrangements allow the grain shipper only 24 hours for purposes of loading the multicar unit. Most country eleva tors do not have the necessary rail...

  3. March to the Brazos - 51 

    E-Print Network [OSTI]

    Unknown

    2006-01-01

    / or cereal. Whole grain or enriched cereal or bread may be used. Waffles, pancakes, muffins or tor tillas made with enriched flour count as bread. verage. Beverages include milk or cocoa for child ren ; ml k, coffee or tea for adults. , *Forn... and pancakes from quick mix. ? Heat frozen waffles, pancakes or tortillas in the microwave topped with a pat of butter. Leftover biscuits may be heated in the microwave to original freshness. ? Sweet rolls, coffee cakes, doughnuts and muffins may...

  4. Homospory 2002: An Odyssey of Progress in Pteridophyte Genetics and Evolutionary Biology

    E-Print Network [OSTI]

    Haufler, Christopher H.

    2002-01-01

    variability housed in each separate population, whereas others dispersed their variability among their pop- ulations. With outcrossing breeding systems, the movement of alleles between individuals and among populations is more likely than if inbreeding... char- acteristics (how genes are shared between individuals and pop- ulations) of species. Population statistics. Population biologists use confor- mance to Hardy-Weinberg (H-W) frequencies as an indica- tor of the type of mating system. Populations...

  5. A review of "European Contexts for English Republicanism" edited by Gaby Mahlberg and Dirk Wiemann 

    E-Print Network [OSTI]

    Schwarz, Marc

    2014-01-01

    also been provided for the reader’s benefit. Prof. Frank E. Sysyn, direc- tor of the Petro Jacyk Central and East European Resource Centre, remains the series editor, assisted by Uliana M. Pasicznyk, managing editor. The consulting editor—Myron M... and its historiographic context. Gaby Mahlberg and Dirk Wiemann, eds. European Contexts for English Republicanism. Burlington, VT: Ashgate, 2013. xii + 273 + 5 illus. $124.95. marc schwarz, university of new hampshire. This volume offers a series...

  6. Visualization and continuous simulation of a space nuclear power system 

    E-Print Network [OSTI]

    Rawal, Rajiv

    1992-01-01

    - tor Systems. In Third International Symposium on Science and Engineering on Cray Supemornputers (Minneapolis, Minnesota, Sept. 9-11). 1987. 6 Ransom, V. H. et al. RELAP5/MODg Code Manual. EG Ic G Idaho, Inc, Idaho National Engineering Laboratory.... There is need for improvement in the current process. Omega is a graphical user interface driven software, which enables quasi real time anal- ysis of reactor characteristics to be gained without either constructing or operating a full scale space nuclear...

  7. Automatic facial expression analysis

    E-Print Network [OSTI]

    Baltrušaitis, Tadas

    2014-04-08

    where the attentiveness of the opera- tor is crucial. Examples of such systems are air traffic control, nuclear power plant surveillance, and operating a motor vehicle. An automated tracking tool could make these systems more secure and efficient, be... California rekindled my interest in the dissertation topic. I would especially like to thank Julien-Charles, Sylwia, Dimitrios and Geovany for all the wonderful conversations we had. This work could not have been possible without the financial support...

  8. Morphology-Based Language Modeling for Arabic Speech Recognition Dimitra Vergyri1

    E-Print Network [OSTI]

    Kirchhoff, Katrin

    features (or fac- tors), i.e. w f1:K. Factors represent morphological, syntac- tic, or semantic word are then constructed over (sub)sets of factors. Using a trigram approximation, this can be expressed as: p(f1:K 1 f1:K 2 ::: f1:K T ) TY t=3 p(f1:K t jf1:K t;1 f1:K t;2 ) (1) Each word is dependent not only on a single

  9. The dual mTORC1 and mTORC2 inhibitor AZD8055 inhibits head and neck squamous cell carcinoma cell growth in vivo and in vitro

    SciTech Connect (OSTI)

    Li, Qiang; Song, Xin-mao; Ji, Yang-yang; Jiang, Hui; Xu, Lin-gen, E-mail: drlingenxu@126.com

    2013-11-01

    Highlights: •AZD8055 induces significant cytotoxic effects in cultured HNSCC cells. •AZD8055 blocks mTORC1 and mTORC2 activation in cultured HNSCC cells. •JNK activation is required for AZD8055-induced HNSCC cell death. •AZD8055 inhibits Hep-2 cell growth in vivo, and was more efficient than rapamycin. -- Abstract: The serine/threonine kinase mammalian target of rapamycin (mTOR) promotes cell survival and proliferation, and is constitutively activated in head and neck squamous cell carcinoma (HNSCC). Thus mTOR is an important target for drug development in this disease. Here we tested the anti-tumor ability of AZD8055, the novel mTOR inhibitor, in HNSCC cells. AZD8055 induced dramatic cell death of HNSCC lines (Hep-2 and SCC-9) through autophagy. AZD8055 blocked both mTOR complex (mTORC) 1 and mTORC2 activation without affecting Erk in cultured HNSCC cells. Meanwhile, AZD8055 induced significant c-Jun N-terminal kinase (JNK) activation, which was also required for cancer cell death. JNK inhibition by its inhibitors (SP 600125 and JNK-IN-8), or by RNA interference (RNAi) alleviated AZD8055-induced cell death. Finally, AZD8055 markedly increased the survival of Hep-2 transplanted mice through a significant reduction of tumor growth, without apparent toxicity, and its anti-tumor ability was more potent than rapamycin. Meanwhile, AZD8055 administration activated JNK while blocking mTORC1/2 in Hep-2 tumor engrafts. Our current results strongly suggest that AZD8055 may be further investigated for HNSCC treatment in clinical trials.

  10. Compensation of the AKT signaling by ERK signaling in transgenic mice hearts overexpressing TRIM72

    SciTech Connect (OSTI)

    Ham, Young-Mi, E-mail: youngmi_ham@hms.harvard.edu [College of Life Science and Biotechnology, Korea University, Seoul (Korea, Republic of); Department of Cell Biology, Harvard Medical School, Boston, MA 02115 (United States); Mahoney, Sarah Jane [Department of Cell Biology, Harvard Medical School, Boston, MA 02115 (United States)

    2013-06-10

    The AKT and ERK signaling pathways are known to be involved in cell hypertrophy, proliferation, survival and differentiation. Although there is evidence for crosstalk between these two signaling pathways in cellulo, there is less evidence for cross talk in vivo. Here, we show that crosstalk between AKT and ERK signaling in the hearts of TRIM72-overexpressing transgenic mice (TRIM72-Tg) with alpha-MHC promoter regulates and maintains their heart size. TRIM72, a heart- and skeletal muscle-specific protein, downregulates AKT-mTOR signaling via IRS-1 degradation and reduces the size of rat cardiomyocytes and the size of postnatal TRIM72-Tg hearts. TRIM72 expression was upregulated by hypertrophic inducers in cardiomyocytes, while IRS-1 was downregulated by IGF-1. TRIM72 specifically regulated IGF-1-dependent AKT-mTOR signaling, resulting in a reduction of the size of cardiomyocytes. Postnatal TRIM72-Tg hearts were smaller than control-treated hearts with inhibition of AKT-mTOR signaling. However, adult TRIM72-Tg hearts were larger than of control despite the suppression of AKT-mTOR signaling. Activation of ERK, PKC-?, and JNK were observed to be elevated in adult TRIM72-Tg, and these signals were mediated by ET-1 via the ET receptors A and B. Altogether, these results suggest that AKT signaling regulates cardiac hypertrophy in physiological conditions, and ERK signaling compensates for the absence of AKT signaling during TRIM72 overexpression, leading to pathological hypertrophy. -- Highlights: • TRIM72 inhibits AKT signaling through ubiquitination of IRS-1 in cardiac cells. • TRIM72 regulates the size of cardiac cells. • TRIM72 regulates size of postnatal TRIM72-overexpressing transgenic mice hearts. • Adult TRIM72-overexpressing transgenic mice hearts showed cardiac dysfunction. • Adult TRIM72 transgenic mice hearts showed higher expression of endothelin receptors.

  11. VOLUME 84, NUMBER 19 P H Y S I C A L R E V I E W L E T T E R S 8 MAY 2000 Evidence for Changing of Cosmic Ray Composition between 1017 and 1018 eV

    E-Print Network [OSTI]

    . C. Knapp,4 S. Ko,1 C. G. Larsen,1 W. Lee,10 E. C. Loh,1 E. J. Mannel,4 J. Matthews,9 J. N. Matthews). The detec- tors are located in the western desert of Utah at 112± W lon- gitude and 40± N latitude. The HiVOLUME 84, NUMBER 19 P H Y S I C A L R E V I E W L E T T E R S 8 MAY 2000 Evidence for Changing

  12. Trends in Gulf Coast Power Supply, Demand, and Costs 

    E-Print Network [OSTI]

    Posey, L. G., Jr.

    1980-01-01

    load and peak load requirements are supplied by fuel oil, gas, and, where available, hydroelectric genera tors. Fuel Cost Forecast Three sources of information provide data to forecast fuel costs for each utility: ? Fuel contracts between... offsets are required for both NMHC and S02' These offsets are regarded as scarce corporate resources by the industries already operating in the area. They will be used carefUlly to optimize industrial growth with the least expensive offsets used first...

  13. Political Poetry in Periodicals and the Shaping of German National Consciousness in the Nineteenth Century

    E-Print Network [OSTI]

    Vanchena, Lorie A.

    2000-01-01

    of the oppositional past that was typical of the German Democratic Republic. I view my study as combining and building upon the work of cultural, social, and literary historians. The first chapter of this book discusses fac­ tors that contributed to the emergence... in neighboring countries. Political opposition movements, fueled by nationalism, liberal constitutionalism, and social protest, had been building behind the facade of monarchical solidar­ ity since the Confederation's inception—despite, but also as a response...

  14. Human Resource Management: Employee Compensation Guide 

    E-Print Network [OSTI]

    Fogleman, Sarah L.; McCorkle, Dean

    2009-04-08

    and driving a trac- tor may require similar skills and therefore can be compensated similarly. Job evaluation is another technique that can be used to establish an equitable wage rate. This 3 method is a more systematic and rational ap- proach to internal... on labor - market information and your compensation objectives) Implement your new system, remembering to: 6. Communicate with your employees about - their needs Review your compensation package - regularly to make sure it is fair, equitable...

  15. Connectivity biomarkers in neurodegenerative tauopathies

    E-Print Network [OSTI]

    Rittman, Timothy

    2015-04-28

    .7 Pairwise group comparison between diagnostic groups used ICA and dual regression. All subjects’ Functional Magnetic Resonance Imaging (fMRI) scans are used in temporal concatenation group ICA to generate a series of timeseries-independent spatial com... . . . . . . . . . . . . . . . . . . . . . . . . . . 164 xxix LIST OF FIGURES LIST OF FIGURES 6.19 Nodes are shown for which the cumulative edge distance differed between PD, PSP and CBS groups. The differences between PD, PSP and CBS bear a similarity to those obtained using eigenvec- tor centrality...

  16. Lesson 8

    E-Print Network [OSTI]

    2015-06-23

    C*n{,nwo."ut th t}r\\ ra*cSo^ g r^ to,r ra-$ tBn. tR; o{

  17. Evaluation of the Procedure Used to Determine Nonlinear Soil Properties In Situ 

    E-Print Network [OSTI]

    Torres, Daniel E.

    2012-02-14

    and springs. 21 Figure 2.6 Displacement History--TOR 2 with ?z= 0.01 m f= 50 Hz 22 Table 2.2 Maximum Values for TOR2 at different depths TOR 2 t (s) d (m) v (m/s) ?z=0.01 m f=50 Hz 2.75E-02 1.39E-08 2.84E-02 1.06E-08 100...-06 4.15E-06 0.97 0.96 4 99 1.06E-06 3.61E-06 0.97 0.98 5 100 9.51E-07 3.19E-06 0.97 1.00 6 100 8.66E-07 2.85E-06 0.97 1.00 7 100 7.94E-07 2.57E-06 0.98 1.00 P=500 N 1 96 8.56E-06 3.48E-05 0.83 0.92 2 98 7.26E-06 2.84E-05 0.85 0.96 3...

  18. Improved DC Gun Insulator Assembly

    SciTech Connect (OSTI)

    Sah, R.; Dudas, A.; Neubauer, M. L.; Poelker, M.; Surles-Law, K. E.L.

    2010-05-23

    Many user fa­cil­i­ties such as syn­chrotron ra­di­a­tion light sources and free elec­tron lasers re­quire ac­cel­er­at­ing struc­tures that sup­port elec­tric fields of 10-100 MV/m, es­pe­cial­ly at the start of the ac­cel­er­a­tor chain where ce­ram­ic in­su­la­tors are used for very high gra­di­ent DC guns. These in­su­la­tors are dif­fi­cult to man­u­fac­ture, re­quire long com­mis­sion­ing times, and often ex­hib­it poor re­li­a­bil­i­ty. Two tech­ni­cal ap­proach­es to solv­ing this prob­lem will be in­ves­ti­gat­ed. First­ly, in­vert­ed ce­ram­ics offer so­lu­tions for re­duced gra­di­ents be­tween the elec­trodes and ground. An in­vert­ed de­sign will be pre­sent­ed for 350 kV, with max­i­mum gra­di­ents in the range of 5-10 MV/m. Sec­ond­ly, novel ce­ram­ic man­u­fac­tur­ing pro­cess­es will be stud­ied, in order to pro­tect triple junc­tion lo­ca­tions from emis­sion, by ap­ply­ing a coat­ing with a bulk re­sis­tiv­i­ty. The pro­cess­es for cre­at­ing this coat­ing will be op­ti­mized to pro­vide pro­tec­tion as well as be used to coat a ce­ram­ic with an ap­pro­pri­ate gra­di­ent in bulk re­sis­tiv­i­ty from the vac­u­um side to the air side of an HV stand­off ce­ram­ic cylin­der. Ex­am­ple in­su­la­tor de­signs are being com­put­er mod­elled, and in­su­la­tor sam­ples are being man­u­fac­tured and test­ed

  19. Genome assortment, not serogroup, defines Vibrio cholerae pandemic strains

    SciTech Connect (OSTI)

    Brettin, Thomas S; Bruce, David C; Challacombe, Jean F; Detter, John C; Han, Cliff S; Munik, A C; Chertkov, Olga; Meincke, Linda; Saunders, Elizabeth; Choi, Seon Y; Haley, Bradd J; Taviani, Elisa; Jeon, Yoon - Seong; Kim, Dong Wook; Lee, Jae - Hak; Walters, Ronald A; Hug, Anwar; Colwell, Rita R

    2009-01-01

    Vibrio cholerae, the causative agent of cholera, is a bacterium autochthonous to the aquatic environment, and a serious public health threat. V. cholerae serogroup O1 is responsible for the previous two cholera pandemics, in which classical and El Tor biotypes were dominant in the 6th and the current 7th pandemics, respectively. Cholera researchers continually face newly emerging and re-emerging pathogenic clones carrying combinations of new serogroups as well as of phenotypic and genotypic properties. These genotype and phenotype changes have hampered control of the disease. Here we compare the complete genome sequences of 23 strains of V. cholerae isolated from a variety of sources and geographical locations over the past 98 years in an effort to elucidate the evolutionary mechanisms governing genetic diversity and genesis of new pathogenic clones. The genome-based phylogeny revealed 12 distinct V. cholerae phyletic lineages, of which one, designated the V. cholerae core genome (CG), comprises both O1 classical and EI Tor biotypes. All 7th pandemic clones share nearly identical gene content, i.e., the same genome backbone. The transition from 6th to 7th pandemic strains is defined here as a 'shift' between pathogenic clones belonging to the same O1 serogroup, but from significantly different phyletic lineages within the CG clade. In contrast, transition among clones during the present 7th pandemic period can be characterized as a 'drift' between clones, differentiated mainly by varying composition of laterally transferred genomic islands, resulting in emergence of variants, exemplified by V.cholerae serogroup O139 and V.cholerae O1 El Tor hybrid clones that produce cholera toxin of classical biotype. Based on the comprehensive comparative genomics presented in this study it is concluded that V. cholerae undergoes extensive genetic recombination via lateral gene transfer, and, therefore, genome assortment, not serogroup, should be used to define pathogenic V. cholerae clones.

  20. Nesfatin-1 inhibits ovarian epithelial carcinoma cell proliferation in vitro

    SciTech Connect (OSTI)

    Xu, Yang; Pang, Xiaoyan; Dong, Mei; Wen, Fang Zhang, Yi

    2013-11-01

    Highlights: •Nesfatin-1 inhibits the proliferation and growth of HO-8910 cells by G1 phase arrest. •Nesfatin-1 enhances HO-8910 cell apoptosis. •Nesfatin-1 inhibits HO-8910 cell proliferation via mTOR and RhoA/ROCK signaling pathway. •The first report of nesfatin-1-mediated proliferation in ovarian epithelial carcinoma. -- Abstract: Nesfatin-1, an 82-amino-acid peptide derived from a 396-amino-acid precursor protein nucleobindin 2 (NUCB2), was originally identified in hypothalamic nuclei involved in the regulation of food intake. It was recently reported that nesfatin-1 is a novel depot specific adipokine preferentially produced by subcutaneous tissue, with obesity- and food deprivation-regulated expression. Although a relation between ovarian cancer mortality and obesity has been previously established, a role of nesfatin-1 in ovarian epithelial carcinoma remains unknown. The aim of the present study is to examine the effect of nesfatin-1 on ovary carcinoma cells proliferation. We found that nesfatin-1 inhibits the proliferation and growth of HO-8910 cells by G1 phase arrest, this inhibition could be abolished by nesfatin-1 neutralizing antibody. Nesfatin-1 enhances HO-8910 cell apoptosis, activation of mammalian target of rapamycin (mTOR) and RhoA/ROCK signaling pathway block the effects of nesfatin-1-induced apoptosis, therefore reverses the inhibition of HO-8910 cell proliferation by nesfatin-1. In conclusion, the present study demonstrated that nesfatin-1 can inhibit the proliferation in human ovarian epithelial carcinoma cell line HO-8910 cells through inducing apoptosis via mTOR and RhoA/ROCK signaling pathway. This study provides a novel regulatory signaling pathway of nesfatin-1-regulated ovarian epithelial carcinoma growth and may contribute to ovarian cancer prevention and therapy, especially in obese patients.

  1. Are Bitcoins Money? 

    E-Print Network [OSTI]

    Nadeau, Benjamin

    2014-09-05

    the price of Bitcoins is the size of the black markets or deep web where Bitcoin is accepted. For that reason, we considered the impact of the closure of the most infamous deep web marketplace to date, The Silk Road. On October 2nd, 2013 the Silk Road... was seized and shut down by the FBI. The Silk Road was a marketplace in the deep web (accessible only from the anonymous web browser Tor). On the Silk Road, users could purchase marijuana, heroin, ecstasy, etc. with Bitcoin exclusively. This created a...

  2. Regmi Research Series ,Year 5, January 1, 1973

    E-Print Network [OSTI]

    Regmi, Mahesh C

    1973-01-01

    , 1973. RIllMI RESEARCH SERIES .. . Cumulative ~ex For 1973 K I( lE 1;11111111101 1. Palpa1s Relatioo5 With Nepal snri Ou-lh . . . 2. The Mu5lim I nvas'on of Np.pal . . 3. An Appeal For Tba Abolition Of Slav&ry . 4. Chronology Of Events... ). An :'ppeal For The Abolition Of Slavery , . . ... ••• ... Regmi ReseBrch (Private) Ltd, Lazimpat, Kathmondu, NeoAl. Page 1 7 15 Compiled by Regmi ~seerch (Private) Ltd for private study and research. Not meant tor public sale or display. Pal...

  3. Compleximetric determination of sulfate with ethylenediaminetetraacetic acid 

    E-Print Network [OSTI]

    Spurlock, William W

    1961-01-01

    tftrstfoay causing fn esse cones the persfeteaoe of original colors well beyoad the point oy stofohfoaotry, sad 1a other oeoes es fndeffnite color reactions The lftersture sites various buffer solutioas an4 sony 1a4fes toro tor the tftratfoa of aetsl foas... would produce fascoureey ia detersfastfoa of other aetal foes ff sagaesiua foa be ?sed ia preperfag s buffer solutiosa This observstioa suggests the pos ?fbilfty of usfag tho neutral saLt oE aegaesfua, slreo4y roasted with QCk~ (Ngi&iygk) ae...

  4. Effects of different treatments on the production of sorghum and yellow maize tortillas 

    E-Print Network [OSTI]

    Choto, Celina Eugenia

    1983-01-01

    cereal food. In Central America, where tortillas are a staple food (Johnson et al 1980), sorghum is used as a partial or t. otal replacement for ma ize (Zea mays) in tortilla making (Ruano and Sergio 1977). In Mexico, where tortillas... torrillas. However, so ghum is used when maize is in short supply oi sorghum is i uch cheaper than maize ( Ruano and Sergio 1 97 7, Ii uegas et a 1 1981) . Its use in tor- r illa is limired because most sorghum varieties produce off colored, poor quality...

  5. A study of the effect of sewer air on concrete 

    E-Print Network [OSTI]

    Ortolani, Walter Albert

    1929-01-01

    boatorsa ~ pzinoiyolxss;n eassneetLon oiLh the?kceebkoiccy or online hoo 4cnsonotaccto4 tSnL eeitntn onaeiobi? boolean kn tho Snsooonoe of ops";ease cnsbotoneoo go4naa ew4fatoa to ecLLFLdoee Sea'a en4 ygahanon ~bgccto4 so' hnsteyioioaieol teoto tho... ayyroeiatioa to the Qgse ator Ceaoat Ooeyogy et Mine, through whoeo gonerooktg thto worik ma aode yew4Ma? te Sr? 4? 4? 1@ehoiy'+ 5a ~ y? jl Olaeeehe, ead Pr? 5? 5? Ieere tor their ooaietoaee oad ertt Leioa? ln thto otal lt w'~e ~ ttn4 oe detesa4ne hg...

  6. An Effective EMS Hardware and Software Interface- The Trained Operator 

    E-Print Network [OSTI]

    Cherry, C. L.

    1986-01-01

    at the plant maintenance reporting device. The operator is now interfacing with the EMS and using it to solve real problems in a particular build ing. On-the-job training (OJT) is an example of application training that can work well or not at all. 'l... HARDWARE AND SOFTWARE THE TRAINED OPER~TQR Christene ~. Cherry Johnson Controls Institute INTERFACE Milwaukee, ABSTRAC'l' A computerized Energy Management Sys tem (EMS) is a tool that allows the user to moni tor and control building heating...

  7. Vegetable Adaptability in the Wichita Valley. 

    E-Print Network [OSTI]

    Pickett, B. S. (Barzalli Stewart)

    1942-01-01

    2 Rlarch 12 Rlarch 12 3Ialrch 12 Rfarch 24 March 24 April 5 April 5 April 5 April 5 April 5 April 5 April 5 Reasonably safe date of planting* Beets Onions Chard Kale Kohl-rabi Mustard English peas Radish ,Spinach Turnip.... Table 2 contains information concerning the limiting temperature fac- tors of certain spring-planted vegetables in reference to harvest periods. Here again it should be remembered that all dates in Table 2, both for planting and harvest, are averages...

  8. Cooking a Cuban Ajiaco: The Columbian Exchange in a Stewpot

    E-Print Network [OSTI]

    Cushman, Gregory T.

    2006-01-01

    , heat 2 tablespoons of lard (manteca) or ¼ cup of olive oil (aceite de oliva). Peel and crush 3 cloves of garlic (ajo); chop 1 large onion (cebolla) and 1 large, seeded green bell pepper (ají pimiento verde); add to the fat at medium- low heat and sauté... in the Age of European Exploration and Exploitation. Columbus himself traveled to the coast of Panama during his fourth and final voyage, though the first European visi- tors had already sailed a few years earlier under Rodrigo de Bastidas. On that particu...

  9. Texas Crop Profile: Peppers 

    E-Print Network [OSTI]

    Hall, Kent D.; Holloway, Rodney L.

    2001-02-13

    -head sorghum can get 10 to 12 feet high. Onion yields have been shown to increase by 50 percent to 100 percent with windbreaks. Currently, only about 10 percent to 25 percent of growers use windbreaks. Planting: Statewide, 80 to 90 percent of the peppers... and liniments. Peppers also play a part in rituals, magic and folklore. Gulamic acid (AuxiGro ? ) is a newly registered agrochemical that acts as a plant growth regula- tor. It enhances crop growth and yield. It is registered on bell peppers and other vegetables...

  10. Commercial Fertilizers in 1915-16. 

    E-Print Network [OSTI]

    Fraps, G. S. (George Stronach)

    1916-01-01

    , potatoes, onions, and cer- n other truck crops, grown on light sandy soils, may give favorable urns for potash. On heavier soils they may, or may not, give re- turns for the potash. A great deal depends upon the possible yield, as the greater.... There have been, in the p~?~t, nlastes of potash. The present prices of pot as!^ are inuch tor; high to n~arrailt its use as a fertilizer. HOME MIXING. It is often possihle fo~ consumers of fertilize]-s to F'aye money by pur- ' chasing acid phospbatc...

  11. Suppression of automotive radio frequency interference 

    E-Print Network [OSTI]

    McLaughlin, Cleon Crosby

    1969-01-01

    of the spark plug and dlstribijtor gap brcakdo'sns is r epr educed by sc'ri tchi ng from an equiva- lent capacj cor befo'. gap Lreakdo'sn to an equivalent gap res j stance aiel:i ndu'':!nce dur. , nrJ b i akdo~sn This capa- bil i tV i ' . &ne &of the major... into lumped clem!'. nts and by providing equiva. 'ent cir uits for the disirib!!tor and spark plug gapa in both co! ducting and non ? conducti. ng states. Unfor unatcly, the state variable rr. odel recuires a grea. i deal of computer time in order...

  12. The modification of a radio frequency Cockcroft Walton generator 

    E-Print Network [OSTI]

    Holt, Joseph Marion

    1954-01-01

    Coeheroft galton yenerator by rodeo%rainy and rebuiMing the entire unit? Th? obgeeti. ves of this nedifieation are to increase the pacer ef' the units te develop a separate pecker supply for heating tho filaaents, te aohisre eompaetnose by oil innsrs... an infinite i@pod?no? "ine? several investir~tor?~t~I9 have obtained th? sana relation fer tho volt~re efficienay of tho gaerator by relubiog th? at: ek te various equivalent transnission line?, the develep cent presented by Lerrain and )'vorhart4' nay be...

  13. Akt Isoforms in Vascular Disease

    E-Print Network [OSTI]

    Yu, Haixiang; Littlewood, Trevor; Bennett, Martin

    2015-04-28

    aneurysm; eNOS, endothelial nitric oxide synthase;mTOR,mammalian target of rapamycin. 44 1223 331505. . This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). orms in vascular disease, Vascul. Pharmacol. (2015... p85 subunit and a catalytic p110 subunit that directly phosphorylates the ribosomal protein kinase p70s6k [29], the rho family polypeptide Rac [30], the serum and glucocorticoid-induced kinases SGK [31–33], and the serine/threonine kinase Akt [34...

  14. Machines vs Malaria: a flow-based preparation of the drug candidate OZ439

    E-Print Network [OSTI]

    Lau, Shing-Hing; Galván, Alicia; Merchant, Rohan R.; Battilocchio, Claudio; Souto, José A.; Berry, Malcolm B.; Ley, Steven V.

    2015-06-16

    -up, there- by making this an attractive approach. By integrating new technologies with traditional batch methods we aimed to over- come some of the synthesis issues associated with the prepara- tion of OZ439. This could in principle pave the way for low... conditions, a solution of 7 in EtOH/H2O (1:1 v/v, 0.05 M) was passed through a packed bed reactor (3 mL internal volume) containing the heterogeneous catalyst (Pd/C, 20 mol %) at 1.00 mL min -1 , feeding the reac- tor with 0.1 L min -1 of H2, whilst...

  15. Predicting market power in wholesale electricity markets

    E-Print Network [OSTI]

    Newbery, David

    of retailers to secure their supplies ahead of time when the spot market or power exchange is only a relatively thin residual market. 2.1 The Residual Supply Index Given the apparent potential to raise prices above the competitive level, electricity wholesale... wholesale markets operate either as pools or power exchanges, in which genera- tors submit o¤ers to supply varying amounts at successively higher prices, and the demand side speci?es the level of demand it would take at successively lower prices.6...

  16. Eight billion asteroids in the Oort cloud

    E-Print Network [OSTI]

    Shannon, Andrew; Jackson, Alan P.; Veras, Dimitri; Wyatt, Mark

    2014-11-25

    rate on the Earth in Section 5, and finish up with some discussion in Section 6. 2 MODEL We perform simulations with the Mercury suite of N-body integra- tors (Chambers 1999), augmented with the Galactic tidal model of Veras & Evans (2013... at a typical velocity of 20.9 km s?1 (Stuart & Binzel 2004) has an impact energy of 3 × 1020 J. By comparison typical LPC nuclei impact velocities are almost three times higher at around 55 km s?1 (Marsden & Steel 1994; Weissman 2007), and thus a Oort...

  17. SIRT1 inactivation induces inflammation through the dysregulation of autophagy in human THP-1 cells

    SciTech Connect (OSTI)

    Takeda-Watanabe, Ai; Kitada, Munehiro; Kanasaki, Keizo; Koya, Daisuke

    2012-10-12

    Highlights: Black-Right-Pointing-Pointer SIRT1 inactivation decreases autophagy in THP-1 cell. Black-Right-Pointing-Pointer Inhibition of autophagy induces inflammation. Black-Right-Pointing-Pointer SIRT1 inactivation induces inflammation through NF-{kappa}B activation. Black-Right-Pointing-Pointer The p62/Sqstm1 accumulation by impairment of autophagy is related to NF-{kappa}B activation. Black-Right-Pointing-Pointer SIRT1 inactivation is involved in the activation of mTOR and decreased AMPK activation. -- Abstract: Inflammation plays a crucial role in atherosclerosis. Monocytes/macrophages are some of the cells involved in the inflammatory process in atherogenesis. Autophagy exerts a protective effect against cellular stresses like inflammation, and it is regulated by nutrient-sensing pathways. The nutrient-sensing pathway includes SIRT1, a NAD{sup +}-dependent histone deacetylase, which is implicated in the regulation of a variety of cellular processes including inflammation and autophagy. The mechanism through which the dysfunction of SIRT1 contributes to the regulation of inflammation in relation to autophagy in monocytes/macrophages is unclear. In the present study, we demonstrate that treatment with 2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide (Sirtinol), a chemical inhibitor of SIRT1, induces the overexpression of inflammation-related genes such as tumor necrosis factor (TNF)-{alpha} and interleukin (IL)-6 through nuclear factor (NF)-{kappa}B signaling activation, which is associated with autophagy dysfunction, as shown through p62/Sqstm1 accumulation and decreased expression of light chain (LC) 3 II in THP-1 cells. The autophagy inhibitor, 3-methyladenine, also induces inflammation-related NF-{kappa}B activation. In p62/Sqstm1 knockdown cells, Sirtinol-induced inflammation through NF-{kappa}B activation is blocked. In addition, inhibition of SIRT1 is involved in the activation of the mammalian target of rapamycin (mTOR) pathway and is implicated in decreased 5 Prime -AMP activated kinase (AMPK) activation, leading to the impairment of autophagy. The mTOR inhibitor, rapamycin, abolishes Sirtinol-induced inflammation and NF-{kappa}B activation associated with p62/Sqstm1 accumulation. In summary, SIRT1 inactivation induces inflammation through NF-{kappa}B activation and dysregulates autophagy via nutrient-sensing pathways such as the mTOR and AMPK pathways, in THP-1 cells.

  18. Production Practices for Irrigated Crops on the High Plains. 

    E-Print Network [OSTI]

    Bonnen, C. A.; McArthur, W. C.; Magee, A. C.; Hughes, W.F.

    1953-01-01

    per acre of cotton for one irrigation on sandy soils but only .85 hour per acre on heavy soils. This saving was possible because the runs were longer and it was not necessary to re-set siphon tubes so often on heavy soils. Also, farmers on sandy... soils had more trouble from washing and from ditches breaking than was experienced on, heavy soils. Sondy Soils Two-.or l*artor Faur-rnr 1.oslsr equlpmsnt *qulpmenl TO?OI how. pel acre YO- Tm~tor Yon TVO~O. 398 48 383 33 Hand "orb Machine work...

  19. Kraith Collected Issue 4 

    E-Print Network [OSTI]

    Lichtenberg, Jacqueline; Clark, Beverly

    1974-01-01

    of the insert. The top of page 14 starts "Through Time and Tear!>". To the bottom of page 15 is untouched. I cut two paragraphs between "unrest" and "I'm so happy". They dealt with Sarek deciding that the proper course of events should be to adopt Kirk...-1 kRAITh coLLeCT?b volume 4 ?blTORS pREfAC? This is m.y first issue as editor of Kraith Collected. This strange state of affairs began when I had the time to type the rrRnuscripts which make up this is!'''e. Then Carol handed down the ultimatum: It...

  20. Cottonseed Meal 

    E-Print Network [OSTI]

    Fuller, F. D. (Frederick Driggs); Fraps, G. S. (George Stronach)

    1919-01-01

    that the present standards, taking into consideration both the manufacturer and consum- er, are the least unfair and the most equitable that could be promulgated. The Division of Feed Control Service realizes that there is a number of factors, any one of which... may occasion fluctu- ations in the quality of cottonseed meal. Some of these fac- tors are seasonal in nature, while others involve the efficiency of the mill machinery and even the miller himself. We do not deem them to be of sufficient...