Liu, Taosheng
Alzheimer's disease (AD) and Parkinson's disease (PD). There are almost 40 million people aged 65 and genetics that promote healthy aging will decrease the incidence of these diseases in the general populationAging is the primary risk factor for the majority of neurodegenerative diseases, including
Liu, Taosheng
Alzheimer's disease (AD) and Parkinson's disease (PD). There are almost 40 million people aged 65 and genetics that promote healthy aging will decrease the incidence of these diseases in the general population James Parkinson first described the clinical symptoms of Parkinson's disease (PD) in his 1817 monograph
Liu, Taosheng
Alzheimer's disease (AD) and Parkinson's disease (PD). There are almost 40 million people aged 65 and genetics that promote healthy aging will decrease the incidence of these diseases in the general population array of neurobiological disorders, including Parkinson's disease, epilepsy, essential tremor, Tourette
Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)
reveal conditions that lead to the disease's signature tangles and plaques in the brain March 12, 2015 Inside Alzheimer's Disease Neuron membrane disruption may underlie...
Educational attainment and rate of cognitive decline in Alzheimer's disease
Hemmy, Laura Sue
2009-05-15T23:59:59.000Z
Alzheimer’s disease (AD) progression and hypotheses of the cognitive reserve theory were investigated by testing for a relation between educational attainment and rate of decline in patients with Mild Cognitive Impairment, possible AD, probable AD...
Educational attainment and rate of cognitive decline in Alzheimer's disease
Hemmy, Laura Sue
2009-05-15T23:59:59.000Z
Alzheimer’s disease (AD) progression and hypotheses of the cognitive reserve theory were investigated by testing for a relation between educational attainment and rate of decline in patients with Mild Cognitive Impairment, possible AD, probable AD...
Synaptic Mitochondrial Pathology in Alzheimer’s Disease
Du, Heng; Guo, Lan; Yan, Shirley ShiDu
2012-06-15T23:59:59.000Z
Significance: Synaptic degeneration, an early pathological feature in Alzheimer's disease (AD), is closely correlated to impaired cognitive function and memory loss. Recent studies suggest that involvement of amyloid-beta ...
S100 Inhibitors: A New Paradigm for Treating Alzheimer’s Disease
Mathai, David 1991-
2011-04-27T23:59:59.000Z
Alzheimer’s disease (AD) is the most common form of dementia, a neurological condition characterized by cognitive impairment and the inability to perform daily tasks. Neuritic protein aggregates in the brain, known as plaques, are a hallmark of AD...
S100 Inhibitors: A New Paradigm for Treating Alzheimer’s Disease
Mathai, David 1991-
2011-04-27T23:59:59.000Z
Alzheimer’s disease (AD) is the most common form of dementia, a neurological condition characterized by cognitive impairment and the inability to perform daily tasks. Neuritic protein aggregates in the brain, known as ...
Why Do We Get Alzheimer's Disease?
Wyss-Coray, Tony (Stanford University) [Stanford University
2006-01-02T23:59:59.000Z
Neurodegenerative diseases and Alzheimer's disease (AD) in particular, are among the major health concerns of the elderly in industrialized societies. The cause of AD is unknown and no disease-modifying treatments are available. The disease is characterized clinically by a progressive dementia and pathologically by the accumulation of protein aggregates in the brain and a profound loss of nerve cells. It has also become clear recently that local immune responses are activated in the AD brain and may have a role in the disease. Our laboratory uses genetic mouse models to understand the disease process and to identify potential therapeutic targets.
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
Xia, Jing; Rocke, David M.; Perry, George; Ray, Monika
2014-01-01T23:59:59.000Z
In late-onset Alzheimer’s disease (AD), multiple brain regions are not affected simultaneously. Comparing the gene expression of the affected regions to identify the differences in the biological processes perturbed can lead to greater insight into AD pathogenesis and early characteristics. We identified differentially expressed (DE) genes from single cell microarray data of four AD affected brain regions: entorhinal cortex (EC), hippocampus (HIP), posterior cingulate cortex (PCC), and middle temporal gyrus (MTG). We organized the DE genes in the four brain regions into region-specific gene coexpression networks. Differential neighborhood analyses in the coexpression networks were performed to identify genes with lowmore »topological overlap (TO) of their direct neighbors. The low TO genes were used to characterize the biological differences between two regions. Our analyses show that increased oxidative stress, along with alterations in lipid metabolism in neurons, may be some of the very early events occurring in AD pathology. Cellular defense mechanisms try to intervene but fail, finally resulting in AD pathology as the disease progresses. Furthermore, disease annotation of the low TO genes in two independent protein interaction networks has resulted in association between cancer, diabetes, renal diseases, and cardiovascular diseases.« less
Alzheimer's Disease and Vitamin E
Empey, Matthew
1998-01-01T23:59:59.000Z
Adelman A. Selegiline and vitamin E in Alzheimer's disease.bomb. Geriatrics Traber MG. Vitamin E in humans: Demand andJ, Cole GM, Schubert D. Vitamin E protects nerve cells from
Neuroimaging of Discourse Processing in Aging and Alzheimer's Disease
Wang, Clarice
2011-12-31T23:59:59.000Z
Detection of very early stages of Alzheimer's Disease (AD) has been an area of difficulty for researchers due to confounds with age. Prose recall has been suggested as a diagnostically sensitive test of episodic memory ...
New Clues in Predicting Alzheimer's Disease
Jagust, William
2013-05-29T23:59:59.000Z
Theres a new clue in the search to identify the harbingers of Alzheimers disease. More info: http://newscenter.lbl.gov/feature-stories/2008/12/16/predict-alzheimers-disease/
Ageing and Dual Task Ability - Development of a new test for Alzheimer's Disease
Young, Gregor
2009-07-03T23:59:59.000Z
Patients with Alzheimer’s disease (AD) display a specific deficit in the ability to perform dual tasks requiring working memory. This executive function deficit has been shown in a number of different research paradigms ...
Proteomic response to metabolic stress and cellular dysfunction in relation to Alzheimer's disease
Herrmann, Abigail Grace
2014-06-28T23:59:59.000Z
Vascular risk factors inducing a state of chronic cerebral hypoperfusion and metabolic stress are thought to influence the onset and progression of Alzheimer’s disease (AD). To investigate the complex molecular ...
Oxidative Damage of DJ-1 Is Linked to Sporadic Parkinson and Alzheimer Diseases*
Li, Lian
Oxidative Damage of DJ-1 Is Linked to Sporadic Parkinson and Alzheimer Diseases* Received an autosomal recessive, early onset familial form of Parkinson disease (PD). However, little is presently known with sporadic PD and AD. Alzheimer disease (AD)2 and Parkinson disease (PD) are the two most common
Journal of Alzheimer's Disease xx (20xx) xxx DOI 10.3233/JAD-132483
Mandal, Pravat K.
-related increase in oxidative stress has been attributed to decreased levels of the brain antioxidant, glutathione contribute to AD pathology. Keywords: Alzheimer's disease, amyloid- peptide, biomarker; glutathione
Li, Lian
and Parkinson Diseases* Received for publication, December 20, 2004, and in revised form, January 18, 2005 oxidative stress has been strongly impli- cated in the pathogenesis of Alzheimer disease (AD) and Parkinson(s) that could potentially be tar- geted by similar therapeutic strategies. Alzheimer disease (AD),1 Parkinson
Motor signs during the course of Alzheimer disease
to 13.1 years (mean 3.6 years) in five centers in Europe and the United States. MOSIs were rated using signs (MOSIs) are common in Alzheimer disease (AD) and may be associated with rates of cognitive decline a standardized portion of the Unified Parkinson's Disease Rating Scale. Overall, 3,030 visits
Systematic review and meta-analysis of transgenic mouse models of Alzheimer’s disease
Egan, Kieren
2014-07-05T23:59:59.000Z
The increasing prevalence of Alzheimer’s disease poses a considerable socioeconomic challenge in the years ahead. There are few clinical treatments available and none capable of halting or slowing the progressive nature ...
Paris-Sud XI, Université de
Aluminum and silica intake in drinking water and the risk of Alzheimer's disease or cognitive,2 , Commenges Daniel1,2 , Helmer Catherine2,3 , Jean-François Dartigues2,3 . Abbreviations: Al, Aluminum; AD, Alzheimer's Disease; MMSE, Mini Mental State Examination; Si, Silica Running head: Aluminum, silica in water
2007-01-01T23:59:59.000Z
in Alzheimer’s disease causes neuronal death. FASEB J. 2001;Manuscript Figure 1. UbB + 1 causes neuritic beading andfound in Alzheimer’s disease causes neuritic beading of
Kim, Hye Yun
Alzheimer's disease (AD) is a lethal progressive neurological disorder affecting the memory. Recently, US Food and Drug Administration mitigated the standard for drug approval, allowing symptomatic drugs that only improve ...
Iron and aluminum interaction with amyloid-beta peptides associated with Alzheimer’s disease
Drochioiu, Gabi; Ion, Laura [Alexandru Ioan Cuza University of Iasi, 11 Carol I, Iasi 700506 (Romania); Murariu, Manuela; Habasescu, Laura [Petru Poni Institute of Macromolecular Chemistry, 41A Grigore Ghica Voda Alley, Iasi 700487 (Romania)
2014-10-06T23:59:59.000Z
An elevation in the concentration of heavy metal ions in Alzheimer’s disease (AD) brain has been demonstrated in many studies. A? precipitation and toxicity in AD brains seem to be caused by abnormal interactions with neocortical metal ions, especially iron, copper, zinc, and aluminum [1–3]. There is increasing evidence that iron and aluminum ions are involved in the mechanisms that underlie the neurodegenerative diseases [4,5]. However, evidence was brought to demonstrate that some A? fragments, at physiological pH, are not able to form binary complexes with Fe(III) ions of sufficient stability to compete with metal hydroxide precipitation [6]. On the contrary, multiple metal ions are known to interact with A? peptides [7]. Consequently, we investigated here the interaction of Fe(II/III) and Al(III) ions with some amyloid-? peptides and fragments that results in peptide aggregation and fibrillation [8,9]. Infrared spectroscopy, atomic force microscopy, scanning electron microscopy, electrophoresis and mass spectrometry demonstrated conformational changes of peptides in the presence of such metals.
Metabonomic Profiling of TASTPM Transgenic Alzheimer's Disease Mouse Model
Hu, Zeping; Browne, Edward R.; Liu, Tao; Angel, Thomas E.; Ho, Paul C.; Chun Yong Chan, Eric
2012-12-07T23:59:59.000Z
Identification of molecular mechanisms underlying early stage Alzheimer’s disease (AD) is important for the development of new therapies against and diagnosis of AD. In this study, non-targeted metabotyping of TASTPM transgenic AD mice was performed. The metabolic profiles of both brain and plasma of TASTPM mice were characterized using gas chromatography-mass spectrometry and compared to those of wild type C57BL/6J mice. TASTPM mice were metabolically distinct compared to wild type mice (Q28 Y = 0.587 and 0.766 for PLS-DA models derived from brain and plasma, respectively). A number of metabolites were found to be perturbed in TASTPM mice in both brain (D11 fructose, L-valine, L-serine, L-threonine, zymosterol) and plasma (D-glucose, D12 galactose, linoleic acid, arachidonic acid, palmitic acid and D-gluconic acid). In addition, enzyme immunoassay confirmed that selected endogenous steroids were significantly perturbed in brain (androstenedione and 17-OH-progesterone) and plasma (cortisol and testosterone) of TASTPM mice. Ingenuity pathway analysis revealed that perturbations related to amino acid metabolism (brain), steroid biosynthesis (brain), linoleic acid metabolism (plasma) and energy metabolism (plasma) accounted for the differentiation of TASTPM and wild-type
Will our final years be golden? Mortality by Alzheimer's disease in the United States
Davis, Mary Ann
2007-09-17T23:59:59.000Z
Alzheimer'Ã?Â?Ã?Â?s disease (AD) is the fifth leading cause of death among the elderly. This study uses National Center for Health Statistics (NCHS) Multiple Cause of Death data for the United States for the years 1998 to ...
Identification of genetic influences in late-onset Alzheimer’s disease (LOAD)
Allen, Mariet
2011-11-25T23:59:59.000Z
Late-onset Alzheimer’s disease (LOAD) is the most common form of dementia, with an incidence of up to 50% in western populations over the age of 85 and a high heritability (up to 80%). The identification of risk factors ...
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
Ullah, Ghanim; Demuro, Angelo; Parker, Ian; Pearson, John E.; Xu, Shang -Zhong
2015-09-08T23:59:59.000Z
Amyloid beta (A?) oligomers associated with Alzheimer’s disease (AD) form Ca2+-permeable plasma membrane pores, leading to a disruption of the otherwise well-controlled intracellular calcium (Ca2+) homeostasis. The resultant up-regulation of intracellular Ca2+ concentration has detrimental implications for memory formation and cell survival. The gating kinetics and Ca2+ permeability of A? pores are not well understood. We have used computational modeling in conjunction with the ability of optical patch-clamping for massively parallel imaging of Ca2+ flux through thousands of pores in the cell membrane of Xenopus oocytes to elucidate the kinetic properties of A? pores. The fluorescence time-series data from individualmore »pores were idealized and used to develop data-driven Markov chain models for the kinetics of the A? pore at different stages of its evolution. Our study provides the first demonstration of developing Markov chain models for ion channel gating that are driven by optical-patch clamp data with the advantage of experiments being performed under close to physiological conditions. As a result, we demonstrate the up-regulation of gating of various Ca2+ release channels due to A? pores and show that the extent and spatial range of such up-regulation increases as A? pores with low open probability and Ca2+ permeability transition into those with high open probability and Ca2+ permeability.« less
Measuring Dementia of the Alzheimer Type More Precisely
Lowe, Deborah Anne
2012-11-29T23:59:59.000Z
Alzheimer’s disease (AD) progressively impairs cognitive and functional abilities. Research on pharmacological treatment of AD is shifting to earlier forms of the disease, including preclinical stages. However, assessment methods traditionally used...
Learning Brain Connectivity of Alzheimer's Disease from Neuroimaging Data
Li, Jing
Learning Brain Connectivity of Alzheimer's Disease from Neuroimaging Data Shui Huang2 , Jing Li2 Recent advances in neuroimaging techniques provide great potentials for effective diagnosis of Alzheimer. In this paper, we consider the problem of learning functional brain connectivity from neuroimaging, which holds
Multivariate and univariate neuroimaging biomarkers of Alzheimer's disease
Multivariate and univariate neuroimaging biomarkers of Alzheimer's disease Christian Habeck January 2008 Available online 14 February 2008 We performed univariate and multivariate discriminant univariate and multivariate analyses produced markers with high classification accuracy in the derivation
Mapping local hippocampal changes in Alzheimer's disease and normal ageing with MRI at 3 Tesla
Thompson, Paul
Mapping local hippocampal changes in Alzheimer's disease and normal ageing with MRI at 3 Tesla and Alzheimer's disease based on high resolution MRI at 3 Tesla. T1-weighted images were acquired from 19
Emotion Regulation Deficits in Frontotemporal Lobar Degeneration and Alzheimer's Disease
Levenson, Robert W.
Emotion Regulation Deficits in Frontotemporal Lobar Degeneration and Alzheimer's Disease Madeleine instructed and spontaneous emotion regulation in patients with frontotemporal lobar degeneration (FTLD, N 32) unwarned without instructions to down-regulate, (b) warned without instructions to down-regulate, and (c
White matter integrity and visual short-term memory binding in familial Alzheimer's disease
Heikkila, Heini
2011-11-23T23:59:59.000Z
The asymptomatic phase of familial Alzheimer’s disease caused by E280A mutation in presenilin-1 gene is characterized by intact performance in traditional neuropsychological tasks including memory, language, and executive ...
Motor signs predict poor outcomes in Alzheimer disease
) in five University-based AD centers in the United States and European Union. Four outcomes, assessed every index, and death. Using a standardized portion of the Unified PD Rating Scale (administered every 6 disease (AD). Methods: A total of 533 patients with AD at early stages (mean Folstein Mini-Mental State
Koyuturk, Mehmet
, Inc., Cleveland OH. * Corresponding author Abstract Alzheimer's and Parkinson's diseases (AD and PD Alzheimer's disease (AD) and Parkinson's disease (PD) are caused by progressive degeneration and/or deathIntegrative Analysis of Common Neurodegenerative Diseases Using Gene Association, Interaction
Longitudinal Medication Usage in Alzheimer Disease Patients
on ChEIs.1,58 In addition to ChEIs and memantine, AD patients are likely to be prescribed other examined in detail patterns of cholinesterase inhibitors (ChEIs) and memantine use and explored characteristics on ChEIs/ memantine use over time. Independent variables included measures of function, cognition
Sotiriou, Sarah
2011-06-29T23:59:59.000Z
Abstract Primary objective: To explore the impact of healthy ageing on dual tasking abilities using a novel dual task paradigm and to consider any clinical implications in aiding the diagnosis of Alzheimer’s disease ...
Paris-Sud XI, Université de
Seropositivity to Herpes Simplex Virus Antibodies and Risk of Alzheimer's Disease: A Population for Studies in Aging, Montreal, Quebec, Canada Abstract Background: Herpes Simplex Virus (HSV) infection has) Seropositivity to Herpes Simplex Virus Antibodies and Risk of Alzheimer's Disease: A Population-Based Cohort
UncorrectedAuthorProof Journal of Alzheimer's Disease xx (20xx) xxx
30 31 Correspondence to: Jesse Mez, Gertrude H. Sergievsky Center, College of Physicians and Surgeons;UncorrectedAuthorProof 2 J. Mez et al. / Language versus Memory Alzheimer's Subgroups tion of patients with AD
Yoo, Suk Joon
2002-01-01T23:59:59.000Z
Submitted to Texas A&M University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE Approved as to the style and content by: Theresa A. Good (Chair of Committee) Gerard L Cote (Member) David M. Ford (Member7-, , g7..., B. S. , Korea University Chair of Advisory Committee Dr. Theresa A. Good Alzheimer's disease (AD) is the most common form of the dementia in the aging population. p-amylotd peptide (Ap l has been indicated as the most important hallmark of AD...
Watts, Amber; Crimmins, Eileen M.; Gatz, Margaret
2008-09-10T23:59:59.000Z
antibodies (Aiello et al 2006). HSV-1 is found in a high proportion of non-AD elderly brains (Jamieson et al 1992) and is most often not found to be associated with dementia. This does not preclude the role of HSV in AD, because presence of a virus... health does not improve despite treatment and proper hygiene, release higher levels of IL-1? and prostaglandin-E2 than patients with non- refractory periodontitis (Hernichel-Gorbach et al 1994). Polymorphisms for genes involved in inflammatory process...
Nanoimaging to Prevent and Treat Alzheimer’s and Parkinson’s Diseases. Scientific/Technical report
Yuri L. Lyubchenko, PhD, DSc
2012-12-20T23:59:59.000Z
This project will develop innovative approaches to characterization of the very early stages of protein aggregation that eventually can be translated to the development of early diagnostic tools and efficient treatments for Alzheimer’s, Parkinson’s and Huntington’s diseases. Funding will be used to acquire nanoimaging technology for nanoscale imaging, manipulation and analysis of biomedical materials to develop treatments that will repair disabled proteins and cure diseases that result from protein malfunction, specifically Alzheimer’s and Parkinson’s diseases. Expected outcomes include tests for early diagnosis and therapeutic treatments for these devastating neurological diseases. To elucidate the mechanisms of protein misfolding, we will establish an extensive program of experimental studies using a broad arsenal of advanced nanoscale and traditional techniques that will be integrated with molecular-scale modeling of protein misfolding and the nucleation of aggregate structures. To identify intracellular machinery or/and multicomponent complexes critically involved in protein misfolding, we will characterize interactions between targeted proteins and specific intracellular components or metabolites that impact on protein conformational pathways leading to protein misfolding accompanied by formation of toxic aggregated morphologies. To design innovative nanotechnology tools for the control of intracellular protein misfolding and aggregation processes, we will develop a predictive molecular scale model for intracellular protein misfolding and the formation of toxic aggregates. Verified through experimental studies, the objective is to establish an enabling foundation for the engineering of novel molecular diagnostics and therapeutics for various cellular pathologies.
Johnstone, Daniel; Milward, Elizabeth A.; Berretta, Regina; Moscato, Pablo
2012-01-01T23:59:59.000Z
Multivariate Protein Signatures of Pre-Clinical Alzheimer’s= 2.3610 213 ). We applied a multivariate approach based onInitiative (2012) Multivariate Protein Signatures of Pre-
Jones, Roger K.
1987-01-01T23:59:59.000Z
Alzheimer's disease (AD) is the most common form of the dementia in the aging population. ?-amyloid peptide (A?) has been indicated as the most important hallmark of AD and also is believed to be the central trigger of ...
Introduction Alzheimer's disease (AD) is the most common type of
Appanna, Vasu
of methionine (MET), 5- hydroxyindoleacetic acid (5-HIAAA), vanillylmandelic acid and xanthosine (8 disturbances in glycolytic glucose breakdown, pyruvate oxidation as well as excessive protein degradation
Review article Nutrition and Alzheimer's disease: The detrimental role of a high carbohydrate diet
Seneff, Stephanie
Review article Nutrition and Alzheimer's disease: The detrimental role of a high carbohydrate diet and Computer Science, MIT Cambridge, MA, USA b Independent Reader of Research, Leeds, United Kingdom c Comando
Tierney, K. M.; Lonie, J. A.; Donaghey, C.; Ebmeier, K. P.; Lee, A.; Herrmann, L. L.; O'Carroll, R. E.
Background. The dual task paradigm (Baddeley et al. 1986; Della Sala et al. 1995) has been proposed as a sensitive measure of Alzheimer's dementia, early in the disease process. Method. We investigated this claim by ...
Neuronal networks with coupling through amyloid beta: towards a theory for Alzheimer's disease
V. Resmi; G. Ambika; R. E. Amritkar; G. Rangarajan
2010-11-18T23:59:59.000Z
Alzheimer's disease (AD) is a common form of dementia observed in the elderly due to neurodegenerative disorder and dysfunction. This arises from alterations in synaptic functioning of neurons leading to cognitive impairment and memory loss. Recent experimental studies indicate that the amyloid beta (A beta) protein, in its dimer and oligomer forms, affects the synaptic activity of neurons in the early stages of AD. However, the precise mechanism underlying A beta induced synaptic depression is still not clearly understood. In this paper, we introduce an electrical model that provides a possible mechanism for this. Our studies show that the competing effects of synaptic activity and the indirect interaction mediated by A beta, can disrupt the synchrony among neurons and severely affect the neuronal activity. This then leads to sub-threshold activity or synaptic silencing. This is in agreement with the reported disruption of cortical synaptic integration in the presence of A beta in transgenic mice. We suggest that direct electrophysiological measurements of A beta activity can establish its role in AD and the possible revival, proposed in our model. The mechanism proposed here is quite general and could account for the role of the relevant protein in other neuronal disorders also.
DEVELOPMENT OF AUTOMATED SOFTWARE PROGRAM FOR THE ANALYSIS OF ALZHEIMER'S DISEASE BETA-AMYLOID SCANS
Mariotti, Jack; Zubal, George
2013-12-18T23:59:59.000Z
Study goal: A Phase 1 evaluation of the kinetics, clearance and cerebral distribution of one novel peripheral benzodiazepine receptors(PBR)positron emission tomography (PET) imaging agent, 18F-PBR-111 following intravenous administration in healthy volunteers and Alzheimer's disease (AD) patients. Short title: Evaluation of PET imaging with PBR-111 in HV and AD subjects Proof of Mechanism. Primary Objective: To evaluate the cerebral distribution of PBR-111 positron emission tomography (PET) for detection/exclusion of microglial activation in patients with Alzheimer's disease subjects compared to healthy volunteers. Secondary objectives: - To assess the dynamic uptake and washout of [18F]PBR-111, a potential imaging bio-marker for inflammatory changes in brain, using positron emission tomography in subjects with Alzheimer's disease (AD) and healthy volunteers (HV). - To perform blood metabolite characterization of [18F]PBR-111 in subjects with AD and HV to determine the nature of metabolites in assessment of [18F]-PBR-111 as a PET brain imaging agent. Name of radioactive drug substance: PBR-111 Dose(s): The applied PBR-111 radioactive dose will be up to 5.0 mCi, diluted in a maximum of 10 ml of saline. The radioligand will be administered as a slow intravenous bolus injection (i.e., 6 sec/ml) into a large vein (e.g., antecubital vein). Route of administration: Intravenous injection Duration of treatment: Single administration of a diagnostic agent Indication: PBR-111 positron emission tomography (PET) imaging has the potential to detect microglial activation. In the presence of PBR-111 uptake (representative of microglial activation), inflammation in the brain can be detected. Diagnosis and main criteria for inclusion: Study participants will be HVs and patients diagnosed with probable AD. HVs must be 18 years of age (at least four subjects 50 years of age) and have no evidence of cognitive impairment or other neurologic disease by medical history. The lack of cognitive impairment will also be based on a Clinical Dementia Rating (CDR) of 0. Patients with probable AD must be 50 years of age and must fulfill the National Institute of Neurological and Communicative Disorders and Stroke, Alzheimer's Disease and Related Disorders Association [NINCDS-ADRDA] criteria for probable AD. The CDR score must be 1.0 and 2.0 and have a modified Hachinski of 4. All HVs and all patients with probable AD must be able to comply with all study procedures. Study design: This is a Phase 1, open-label, single-center, non-randomized single dose study to assess the kinetics, clearance and cerebral distribution of PBR-111 PET imaging in detecting microglial activation in the brain in patients with probable AD compared to HVs. All aspects related to image acquisition, processing, and visual as well as quantitative evaluation will be developed, optimized, and validated (where required). Each subject will be required to visit the study center during the screening phase and on the PBR-111 PET imaging day (baseline). A telephone follow-up visit will be performed 7 days (± 3 days) after PBR-111 PET administration. At the screening visit, each subject (or caregiver in the case of AD subjects) will be asked to provide written informed consent or assent. During the screening phase (maximum duration of 60 days) subject medical, neurological, and surgical history, clinical assessments, and a neuro-psychiatric evaluation will be performed on all eligible subjects. Subjects will be allowed to leave the center after all evaluations have been completed. During this period an MRI of the brain will be performed during the screening period. If an MRI of the brain has been performed within six months of the imaging visit using the methods described in the protocol, and there has been no medically significant events in the interim, the previous MRI may be used. During the PBR-111 PET imaging day, all subjects will receive a single intravenous injection of PBR-111 and scanning will be performed over a 3.5 hour period. Each subject will have a telephone follow-up 7 da
Repurposing Drugs for Alzheimer's Disease and Related Dementias Request for Proposals (RFP)
Charette, André
Repurposing Drugs for Alzheimer's Disease and Related Dementias Request for Proposals (RFP) Neurodegenerative diseases represent one of the most difficult classes of diseases for which to develop drugs, yet, offering a huge opportunity to target some of these pathways with repurposed drugs approved
Monte Carlo Simulation of Alzheimer's Disease in the United States: 2010-2060
Feres, Renato
Monte Carlo Simulation of Alzheimer's Disease in the United States: 2010-2060 Michael Blech concerns facing the United States over the next 50 years. This progressive disease is currently the sixth on the United States population, and second, the simulation models both prevalence and mortality. Both
Paris-Sud XI, Université de
1 What do family caregivers of Alzheimer's disease patients desire in smart home technologies misuse. Keywords: Smart homes, Dementia care, Alzheimer's disease, Family caregivers, Acceptability. I. Introduction This article presents a survey on the views and perceptions of innovative smart home technologies
Boyer, Edmond
(AD) and if its profile remains the same between two examinations. A specifically designed protocol was administered to 16 AD patients in the mild to severe stages of dementia and to 16 matched healthy controls patients. The patterns of their responses were similar to those of controls, and remained consistent over
DICOVERY OF "BIOMARKERS" FOR ALZHEIMER'S DISEASE PREDICTION FROM STRUCTURAL MR IMAGES
DICOVERY OF "BIOMARKERS" FOR ALZHEIMER'S DISEASE PREDICTION FROM STRUCTURAL MR IMAGES Y. Liu1,2,3 , L. A. Teverovskiy2 , O. L. Lopez3 , H. Aizenstein3 , C. C. Meltzer3,4 , J. T. Becker3 1 Penn State discrimination using high-resolutionMagnetic Resonance (MR) brain images. We focus on the exploration of a very
Will our final years be golden? Mortality by Alzheimer's disease in the United States
Davis, Mary Ann
2007-09-17T23:59:59.000Z
Page A.1 Magnetic Resonance Imaging (MRI) of Brain Atrophy in Alzheimer's Disease........................................................... 125 A.2 Population Pyramid Summary for the United States ............. 126 A.3 Percentage..., Decedents Over Age 60, United States 1998-2002.................................................................... 157 G.2 Frequency of Mortality by Ethnicity in Decedents Over Age 60 in the United States, 1998...
Identifying Alzheimers Disease-Related Brain Regions from Multi-Modality Neuroimaging Data
Li, Jing
1 Identifying Alzheimers Disease-Related Brain Regions from Multi-Modality Neuroimaging Data using sensitivity and specificity. The fast growing neuroimaging techniques hold great promise.8 Research so far has focused on single neuroimaging modalities. However, as different modalities9 provide complementary
Thompson, Paul
in Alzheimer's disease Yi-Yu Chou,a Natasha Leporé,a Greig I. de Zubicaray,b Owen T. Carmichael,c James T. Becker,d Arthur W. Toga,a and Paul M. Thompsona, a Laboratory of Neuro Imaging, Department of Neurology
Thompson, Paul
ALZHEIMER'S DISEASE Yi-Yu Chou1 , Natasha Leporé1 , Priya Saharan1 , Sarah K. Madsen1 , Xue Hua1 , Clifford R. Jack2 , Leslie M. Shaw3 , John Q. Trojanowski3 , Michael W. Weiner4 , Arthur W. Toga1 , Paul M
A State-Wide Research Network for Alzheimer's Disease
Mintzer, Jacobo E.; Bachman, D. L.; Stuckey, M.; Ebeling, M.; Wagner, M. T.; Evans, W. J.; Hirth, V.; Walker, A.; Joglekar, R.; Faison, W.
2014-03-13T23:59:59.000Z
The Specific Aim of the proposal was to develop an administrative structure that will facilitate the development of AD research across the state of SC by providing key services such as (but not limited to) seeking funding research opportunities, financial tracking, regulatory management, central recruitment, training for investigators and coordinators, data collection, data storing, and data processing to researchers across the state.
Mandal, Pravat K.
447 Alzheimer's Disease: NMR Studies of Asialo (GM1) and Trisialo (GT1b) Ganglioside Interactions-like membranes composed of gangliosides. Ganglioside GM1 binds tightly with A and it is specu- lated that GM1 dodecyl sulphate (SDS) micelles, a membrane-mimicking environment. These studies reveal that asialoGM1
Thompson, Paul
. Leow a,b , Yi-Yu Chou a , April J. Ho a , Boris Gutman a , Arthur W. Toga a , Clifford R. Jack Jr d,j , Gene E. Alexander l , Michael W. Weiner i,j,k,l , Paul M. Thompson a, and the Alzheimer's Disease
What Do Family Caregivers of Alzheimer's Disease Patients Desire in Smart Home Technologies?
Rialle, Vincent; Guigui, Carole; Hervé, Christian
2009-01-01T23:59:59.000Z
Objectives - The authors' aim was to investigate the representations, wishes, and fears of family caregivers (FCs) regarding 14 innovative technologies (IT) for care aiding and burden alleviation, given the severe physical and psychological stress induced by dementia care, and the very slow uptake of these technologies in our society. Methods - A cluster sample survey based on a self-administered questionnaire was carried out on data collected from 270 families of patients with Alzheimer's disease or related disorders, located in the greater Paris area. Multiple Correspondence Analysis was used in addition to usual statistical tests to identify homogenous FCs clusters concerning the appreciation or rejection of the considered technologies. Results - Two opposite clusters were clearly defined: FCs in favor of a substantial use of technology, and those rather or totally hostile. Furthermore the distributions of almost all the answers of appreciations were U shaped. Significant relations were demonstrated betwee...
Key residues for the oligomerization of A{beta}42 protein in Alzheimer's disease
Ngo, Sam [Department of Neurology, Brain Research Institute, Molecular Biology Institute, University of California, Los Angeles, CA 90095 (United States)] [Department of Neurology, Brain Research Institute, Molecular Biology Institute, University of California, Los Angeles, CA 90095 (United States); Guo, Zhefeng, E-mail: zhefeng@ucla.edu [Department of Neurology, Brain Research Institute, Molecular Biology Institute, University of California, Los Angeles, CA 90095 (United States)] [Department of Neurology, Brain Research Institute, Molecular Biology Institute, University of California, Los Angeles, CA 90095 (United States)
2011-10-28T23:59:59.000Z
Highlights: Black-Right-Pointing-Pointer A{beta} oligomers are neurotoxins and likely the causing agents for Alzheimer's disease. Black-Right-Pointing-Pointer A{beta}42 fusion protein form globular oligomers. Black-Right-Pointing-Pointer A{beta}42 fusion protein oligomers contain SDS-resistant tetramers and hexamers. Black-Right-Pointing-Pointer Cysteine substitutions at residues 31, 32, 34, 39-41 disrupt A{beta}42 oligomerization. -- Abstract: Deposition of amyloid fibrils consisting of amyloid {beta} (A{beta}) protein as senile plaques in the brain is a pathological hallmark of Alzheimer's disease. However, a growing body of evidence shows that soluble A{beta} oligomers correlate better with dementia than fibrils, suggesting that A{beta} oligomers may be the primary toxic species. The structure and oligomerization mechanism of these A{beta} oligomers are crucial for developing effective therapeutics. Here we investigated the oligomerization of A{beta}42 in the context of a fusion protein containing GroES and ubiquitin fused to the N-terminus of A{beta} sequence. The presence of fusion protein partners, in combination with a denaturing buffer containing 8 M urea at pH 10, is unfavorable for A{beta}42 aggregation, thus allowing only the most stable structures to be observed. Transmission electron microscopy showed that A{beta}42 fusion protein formed globular oligomers, which bound weakly to thioflavin T and Congo red. SDS-PAGE shows that A{beta}42 fusion protein formed SDS-resistant hexamers and tetramers. In contrast, A{beta}40 fusion protein remained as monomers on SDS gel, suggesting that the oligomerization of A{beta}42 fusion protein is not due to the fusion protein partners. Cysteine scanning mutagenesis at 22 residue positions further revealed that single cysteine substitutions of the C-terminal hydrophobic residues (I31, I32, L34, V39, V40, and I41) led to disruption of hexamer and tetramer formation, suggesting that hydrophobic interactions between these residues are most critical for A{beta}42 oligomerization.
Jones, Rob; Sheehan, Bart; Phillips, Patrick; Juszczak, Ed; Adams, Jessica; Baldwin, Ashley; Ballard, Clive; Banerjee, Sube; Barber, Bob; Bentham, Peter; Brown, Richard; Burns, Alistair; Dening, Tom; Findlay, David; Gray, Richard; Griffin, Mary; Holmes, Clive; Hughes, Alan; Jacoby, Robin; Johnson, Tony; Jones, Roy; Knapp, Martin; Lindesay, James; McKeith, Ian; McShane, Rupert; Macharouthu, Ajay; O'Brien, John; Onions, Caroline; Passmore, Peter; Raftery, James; Ritchie, Craig; Howard, Rob; Domino-ad Team
2009-07-24T23:59:59.000Z
) factorial (2 × 2) design, whether there is worthwhile ben- efit for patients, for whom there is uncertainty on whether related quality of life after 12 months compared to those patients continuing on either monotherapy; Trials 2009, 10:57 http... and health related quality of life. Methods Design This is a pragmatic, multicentre, double-blind (with patient, carer, clinician, outcome assessor and investiga- tors blinded), randomized, placebo controlled (double dummy), parallel group, 2 × 2 factorial...
Multivariate Data Analysis for Neuroimaging Data: Overview and Application to Alzheimer's Disease
REVIEW Multivariate Data Analysis for Neuroimaging Data: Overview and Application to Alzheimer for sophisticated neuroimaging analysis becomes more apparent. Multivariate analysis techniques have recently. Multivariate techniques also lend themselves much better to prospective application of results from
Vialatte, François
Stochastic event synchrony Hilbert transform Wavelet transform It is well known that EEG signals of Alzheimer with an increase of power in the low-frequency range (delta and theta) and a decrease of power in the high. It is noteworthy, however, that those two effects are not always easily detectable: there tends to be large
Wenk, Gary
and Parkinson's disease. These findings are also reported in inherited diseases such as phenylketonuria involved. Examples include Alzheimer's disease (AD), Parkinson's disease (PD), and others [1]. In most in these diseases, elicited by either genetic alterations (mitochondrial or nuclear DNA) or exogenous toxins
New therapeutic targets in Alzheimer's disease: brain deregulation of calcium and zinc
Corona, C; Pensalfini, A; Frazzini, V; Sensi, S L
2011-01-01T23:59:59.000Z
39;s disease: brain deregulation of calcium and zinc [39;s disease: brain deregulation of calcium and zinc39;s disease: brain deregulation of calcium and zinc Gotz
Mak, Elijah; Su, Li; Williams, Guy B.; Watson, Rosie
2015-02-07T23:59:59.000Z
and HC (p = 0.95). There were no differences in cognitive decline between DLB and AD. In the combined dementia group (AD and DLB), younger age was associated with higher atrophy rates (r = 0.49, p < 0.01). Conclusions AD showed a faster rate of global...
iCons, 2011 Alzheimers and Aluminum: Lesson Plan
Auerbach, Scott M.
© iCons, 2011 Alzheimers and Aluminum: Lesson Plan Handouts to explore mechanistic link between Alzheimer's and aluminum 5. Brief proposal expanding Points to Aluminum's Link With Alzheimer's Disease" from 1989. Provide handout
Treusch, Sebastian
2011-01-01T23:59:59.000Z
Numerous neurodegenerative diseases are pathologically characterized by idiosyncratic protein amyloid inclusions. Not surprisingly amyloid fibrils have long been proposed to be the toxic protein species in these neurodegenerative ...
: A Longitudinal Analysis of the National Alzheimer's Coordinating Center (NACC) Database Jesse Mez1: A dysexecutive subgroup of AD has a unique disease course in addition to cognitive phenotype. Citation: Mez J June 3, 2013 Copyright: ß 2013 Mez et al. This is an open-access article distributed under the terms
Morimoto, Richard
of destabilized proteins. Genetic mutations in conformational disease-associated proteins, as well as exposure in the genetic background may account for some of the cell-type specificity observed in disease, even when neurodegenerative diseases, including Alzheimer's Dis- ease (AD), Parkinson's Disease (PD), Amyotrophic Lat- eral
BETWEEN DESTINY AND DISEASE: GENETICS AND MOLECULAR PATHWAYS OF CENTRAL NERVOUS SYSTEM AGING
Sibille, Etienne
BETWEEN DESTINY AND DISEASE: GENETICS AND MOLECULAR PATHWAYS OF CENTRAL NERVOUS SYSTEM AGING BETWEEN DESTINY AND DISEASE: GENETICS AND MOLECULAR PATHWAYS OF CNS AGING Christin Ann Glorioso, Ph onset neurodegenerative diseases such as Alzheimer's(AD) and Parkinson's diseases(PD), to earlier onset
ARTICLE IN PRESS 3 Mapping cortical change in Alzheimer's disease, brain development,
Thompson, Paul
's disease, schizo- 19 phrenia, normal aging, and abnormal brain development based on 20 imaging data, not seen in individual brain scans, often emerge when 45population-based brain data are averaged School of Medicine, Los Angeles, CA 90095-1769, United States 9 b Child Psychiatry Branch, NIMH, Bethesda
Synchronizing an aging brain: can entraining circadian clocks by food slow Alzheimer's disease?
Kent, Brianne A.
2014-09-01T23:59:59.000Z
-hypothalamic actions of ghrelin on neuronal function. Trends Neurosci. 34, 31–40. doi: 10.1016/j.tins.2010.10.001 Anea, C. B., Zhang, M., Stepp, D. W., Simkins, G. B., Reed, G., Fulton, D. J., et al. (2009). Vascular disease in mice with a dysfunctional circadian clock... : 10.1207/s15402010bsm0101_4 Andrews, Z. B. (2011). The extra-hypothalamic actions of ghrelin on neuronal function. Trends Neurosci. 34, 31–40. doi: 10.1016/j.tins.2010.10.001 Anea, C. B., Zhang, M., Stepp, D. W., Simkins, G. B., Reed, G., Fulton, D. J...
Wurtman, Richard
-enzymatic processes (e.g., acting as antioxidants). This article first considers the evidence that deficiencies subnormal levels of a characteristic peptide, A-beta 142, in cerebrospinal fluid (CSF) and abnormal brain
Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)
of uncharged lipids, as is normally the case with the exteriors of young, healthy brain cells, the proteins do not significantly interact with it. But when the membrane...
Neuroinflammation in Alzheimer's disease
2015-01-01T23:59:59.000Z
PS, Schmeidler J, Pasinetti GM. Randomized pilot study of6, interleukin 1?, and GM-CSF. 66 This observation suggests
Neuroinflammation in Alzheimer's disease
2015-01-01T23:59:59.000Z
pathogens. Activation of the proteolytic complement cascade results in opsonisation and, ultimately, in lysis of microorganisms.
Rajendran, Reshmi; Minqin, Ren [Centre for Ion Beam Applications, Department of Physics, Blk S 12, Faculty of Science, National University of Singapore, 2, Science Drive 3, Singapore 117542 (Singapore)] [Centre for Ion Beam Applications, Department of Physics, Blk S 12, Faculty of Science, National University of Singapore, 2, Science Drive 3, Singapore 117542 (Singapore); Ynsa, Maria Dolores [Centro de Micro-Analisis de Materiales (CMAM), Universidad Autonoma de Madrid, Campus de Cantoblanco, 28049 Madrid (Spain)] [Centro de Micro-Analisis de Materiales (CMAM), Universidad Autonoma de Madrid, Campus de Cantoblanco, 28049 Madrid (Spain); Casadesus, Gemma [Department of Neurosciences, Case Western Reserve University, Cleveland, OH 44106 (United States)] [Department of Neurosciences, Case Western Reserve University, Cleveland, OH 44106 (United States); Smith, Mark A.; Perry, George [Department of Pathology, Case Western Reserve University, Cleveland, OH 44106 (United States)] [Department of Pathology, Case Western Reserve University, Cleveland, OH 44106 (United States); Halliwell, Barry [Department of Biochemistry, National University of Singapore (Singapore)] [Department of Biochemistry, National University of Singapore (Singapore); Watt, Frank, E-mail: phywattf@nus.edu.sg [Centre for Ion Beam Applications, Department of Physics, Blk S 12, Faculty of Science, National University of Singapore, 2, Science Drive 3, Singapore 117542 (Singapore)] [Centre for Ion Beam Applications, Department of Physics, Blk S 12, Faculty of Science, National University of Singapore, 2, Science Drive 3, Singapore 117542 (Singapore)
2009-04-24T23:59:59.000Z
There is considerable interest in the role of metals such as iron, copper, and zinc in amyloid plaque formation in Alzheimer's disease. However to convincingly establish their presence in plaques in vivo, a sensitive technique is required that is both quantitatively accurate and avoids isolation of plaques or staining/fixing brain tissue, since these processes introduce contaminants and redistribute elements within the tissue. Combining the three ion beam techniques of scanning transmission ion microscopy, Rutherford back scattering spectrometry and particle induced X-ray emission in conjunction with a high energy (MeV) proton microprobe we have imaged plaques in freeze-dried unstained brain sections from CRND-8 mice, and simultaneously quantified iron, copper, and zinc. Our results show increased metal concentrations within the amyloid plaques compared with the surrounding tissue: iron (85 ppm compared with 42 ppm), copper (16 ppm compared to 6 ppm), and zinc (87 ppm compared to 34 ppm).
Yoo, Suk Joon
2002-01-01T23:59:59.000Z
to A? toxicity. In this work, we explored the role of gangliosides and cholesterol in the mechanism of A? neurotoxicity in AD. Specifically, we investigated the feasibility that the binding between A? and the cell membrane, which is proposed...
Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model
Brinton, Roberta Diaz
Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model and suggests therapeutic targets for prevention of AD. ABAD aging bioenergetics brain hypometabolism mitochondria The essential role of mitochondria in cellular bioenergetics and survival has been well
Neddylation dysfunction in Alzheimer's disease
Chen, Yuzhi
Ubiquitin-dependent proteolysis is a major mechanism that downregulates misfolded proteins or those that have finished a programmed task. In the last two decades, neddylation has emerged as a major regulatory pathway for ...
Enhancing synaptogenesis in diseases characterized by deficiencies in brain synapses
Wurtman, Richard Jay
The loss of hippocampal and cortical synapses, resulting from impaired synaptogenesis, accelerated synaptic degeneration, or both, is one of the earliest neuropathologic findings in Alzheimer’s Disease and is the finding ...
Langford, Zachary Denver
2012-12-31T23:59:59.000Z
As the Alzheimer's disease process progresses in time measurements of cognitive functioning exhibit nonlinearity. Multiphase models were used to quantify this nonlinearity for thirty-six well characterized individuals(~12 observations per individual...
Multimodal Imaging of Alzheimer Pathophysiology in the Brain's Default Mode Network
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
Shin, Jonghan; Kepe, Vladimir; Small, Gary W.; Phelps, Michael E.; Barrio, Jorge R.
2011-01-01T23:59:59.000Z
The spatial correlations between the brain's default mode network (DMN) and the brain regions known to develop pathophysiology in Alzheimer's disease (AD) have recently attracted much attention. In this paper, we compare results of different functional and structural imaging modalities, including MRI and PET, and highlight different patterns of anomalies observed within the DMN. Multitracer PET imaging in subjects with and without dementia has demonstrated that [C-11]PIB- and [F-18]FDDNP-binding patterns in patients with AD overlap within nodes of the brain's default network including the prefrontal, lateral parietal, lateral temporal, and posterior cingulate cortices, with the exception of the medial temporalmore »cortex (especially, the hippocampus) where significant discrepancy between increased [F-18]FDDNP binding and negligible [C-11]PIB-binding was observed. [F-18]FDDNP binding in the medial temporal cortex—a key constituent of the DMN—coincides with both the presence of amyloid and tau pathology, and also with cortical areas with maximal atrophy as demonstrated by T1-weighted MR imaging of AD patients.« less
Free membership Agriculture Alzheimer Astronomy
Lovley, Derek
Membership Free membership signup! Categories Agriculture Alzheimer Astronomy Astrophysics Bacteria that was released to the environment as a result of ore milling, nuclear fuel fabrication or processing activities
Discriminative MR Image Feature Analysis for Automatic Schizophrenia and Alzheimer's
neuroradiologists. Most work in automatic or semi- automatic MR neuroimage classification [1,5,14,7,16] has beenDiscriminative MR Image Feature Analysis for Automatic Schizophrenia and Alzheimer's Disease Classification Yanxi Liu1 , Leonid Teverovskiy1 , Owen Carmichael1 , Ron Kikinis2 , Martha Shenton2 , Cameron S
Body Composition in Early Alzheimer's Disease
Burns, Jeffrey M.
2009-01-09T23:59:59.000Z
measures of memory (WMS-R Logical Memory I and II, Free and Cued Selective Reminding Task), language (Boston Naming Test ? 15 item), working memory (WMS III Digit Span Forwards and Backwards, WAIS Letter-number sequencing), executive function...
Alberta Alzheimer Research Program III Description
Michelson, David G.
Alberta Alzheimer Research Program III Description The Alzheimer Society of Alberta and Northwest Territories (ASANT) and the Alberta Prion Research Institute (Prion Institute) present the Alberta Alzheimer Research Program (AARP) III. The AARP III allows qualified Alberta-based investigators to seek funding
Structural imaging biomarkers of Alzheimer's disease: predicting disease progression
Boyer, Edmond
relatively high accuracy on all baseline ADNI1 data (excluding the 3% failing 5800), Bor- deaux, France c McConnell Brain Imaging Centre, Montreal Neurological@cfin.au.dk 1 Data used in the preparation of this article were obtained from
Breitling, Rainer
, including Parkinson's disease, polyglutamine expansion diseases and Alzheimer's disease, are associated used to model these diseases and high throughput genetic screens using these models have led-analysis #12;3 Introduction Several age-related neurodegenerative diseases, including Parkinson's disease
Instability corners in AdS space
Fotios V. Dimitrakopoulos; Ben Freivogel; Matthew Lippert; I-Sheng Yang
2014-10-07T23:59:59.000Z
We investigate whether arbitrarily small perturbations in global AdS space are generically unstable and collapse into black holes on the time scale set by gravitational interactions. We argue that current evidence, combined with our analysis, strongly suggests that a set of nonzero measure in the space of initial conditions does not collapse on this time scale. On the other hand, existing results do not provide an equally strong indication whether the unstable solutions also form a set of nonzero measure. We perform an analysis in position space to address this puzzle, and our formalism allows us to directly address the vanishing-amplitude limit. We show that gravitational self-interaction leads to tidal deformations which are equally likely to focus or defocus energy, and we sketch the phase diagram accordingly. We also clarify the connection between gravitational evolution in global AdS and holographic thermalization.
Refined Holographic Entanglement Entropy for the AdS Solitons and AdS black Holes
Masafumi Ishihara; Feng-Li Lin; Bo Ning
2013-04-04T23:59:59.000Z
We consider the refinement of the holographic entanglement entropy for the holographic dual theories to the AdS solitons and AdS black holes, including the corrected ones by the Gauss-Bonnet term. The refinement is obtained by extracting the UV-independent piece of the holographic entanglement entropy, the so-called renormalized entanglement entropy which is independent of the choices of UV cutoff. Our main results are (i) the renormalized entanglement entropies of the AdS$_{d+1}$ soliton for $d=4,5$ are neither monotonically decreasing along the RG flow nor positive definite, especially around the deconfinement/confinement phase transition; (ii) there is no topological entanglement entropy for AdS$_5$ soliton even with Gauss-Bonnet correction; (iii) for the AdS black holes, the renormalized entanglement entropy obeys an expected volume law at IR regime, and the transition between UV and IR regimes is a smooth crossover even with Gauss-Bonnet correction; (iv) based on AdS/MERA conjecture, we postulate that the IR fixed-point state for the non-extremal AdS soliton is a trivial product state.
RAGE and Alzheimer’s Disease: A Progression Factor for Amyloid-?-Induced Cellular Perturbation?
Yan, Shirley ShiDu; Bierhaus, Angelika; Nawroth, Peter P.; Stern, David M.
2009-04-01T23:59:59.000Z
Receptor for Advanced Glycation Endproducts (RAGE) is a multiligand member of the immunoglobulin superfamily of cell surface molecules which serves as a receptor for amyloid-? peptide (A?) on neurons, microglia, astrocytes, ...
Exploring candidate genes for human brain diseases from a brain-specific gene network
Jiang,Tianzi
identifying multiple candidate genes for genetic human brain diseases from a brain-specific gene network; Candidate genes Many common human brain diseases, such as schizo- phrenia, Alzheimer's disease, Parkinson's disease, depres- sion, etc., have prominent genetic components [1,2]. Most researchers think that large
What is new and exciting in Alzheimer's disease research?
Jonsson1 et al., Nature | Letter 2012 1deCODE genetics, 101 Reykjavik, Iceland #12;#12;Alan Turing) at the National Codes Centre at Bletchley Park In 2012 two 70-year-old papers by Alan Turing on the theory of code
Decreasing your risk for Alzheimer's disease through diet
) #12;Resveratrol A plant-based polyphenol In dark red/purple plants Apples Blueberries Blackberries Acai berries Red grapes #12;Resveratrol Antioxidant, anti-inflammatory In animal models, shown
DISEASE-SPECIFIC PROBABILISTIC BRAIN ATLASES
Thompson, Paul
algorithms for knowledge-based image analysis, automated image labeling, tissue classification, data mining School of Medicine, Los Angeles, CA 2 Alzheimer's Disease Center, UCLA School of Medicine, Los Angeles Westwood Plaza, Los Angeles, CA 90095-1769 Phone: (310) 206-2101 Fax: (310) 206-5518 E-mail: thompson
Johnstone, Daniel; Milward, Elizabeth A.; Berretta, Regina; Moscato, Pablo
2012-01-01T23:59:59.000Z
Peptide (BNP) *Betacellulin (BTC) CD5 Fas Ligand (FasL)II & Betacellulin (ApoA-II – BTC) Angiopoietin-2 & Neuronal
Li, Lian
pathological feature common to many age- related neurodegenerative diseases, including Parkinson's disease-related neurodegenerative diseases, including Parkinson's disease (PD), Alzheimer's disease (AD), Huntington's disease (HD Publishers Ltd. Aggresome Formation and Neurodegenerative Diseases: Therapeutic Implications J.A. Olzmann1
Insight into Alzheimer's, cancer, anemia gleaned from ribosome...
Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)
Insights from ribosome research Insight into Alzheimer's, cancer, anemia gleaned from ribosome research Groundbreaking study of the human ribosome reveals tiny molecular machine is...
Large rotating AdS black holes from fluid mechanics
Sayantani Bhattacharyya; Subhaneil Lahiri; R. Loganayagam; Shiraz Minwalla
2008-07-25T23:59:59.000Z
We use the AdS/CFT correspondence to argue that large rotating black holes in global AdS(D) spaces are dual to stationary solutions of the relativistic Navier-Stokes equations on S**(D-2). Reading off the equation of state of this fluid from the thermodynamics of non-rotating black holes, we proceed to construct the nonlinear spinning solutions of fluid mechanics that are dual to rotating black holes. In all known examples, the thermodynamics and the local stress tensor of our solutions are in precise agreement with the thermodynamics and boundary stress tensor of the spinning black holes. Our fluid dynamical description applies to large non-extremal black holes as well as a class of large non-supersymmetric extremal black holes, but is never valid for supersymmetric black holes. Our results yield predictions for the thermodynamics of all large black holes in all theories of gravity on AdS spaces, for example, string theory on AdS(5) x S**5 and M theory on AdS(4) x S**7 and AdS(7) x S**4.
Branes in AdS and pp-wave spacetimes
Kostas Skenderis; Marika Taylor
2002-07-03T23:59:59.000Z
We find half supersymmetric AdS-embeddings in AdS_5 x S^5 corresponding to all quarter BPS orthogonal intersections of D3-branes with Dp-branes. A particular case is the Karch-Randall embedding AdS_4 x S^2. We explicitly prove that these embeddings are supersymmetric by showing that the kappa symmetry projections are compatible with half of the target space Killing spinors and argue that all these cases lead to AdS/dCFT dualities involving a CFT with a defect. We also find an asymptotically AdS_4 x S^2 embedding that corresponds to a holographic RG-flow on the defect. We then consider the pp-wave limit of the supersymmetric AdS-embeddings and show how it leads to half supersymmetric D-brane embeddings in the pp-wave background. We systematically analyze D-brane embeddings in the pp-wave background along with their supersymmetry. We construct all supersymmetric D-branes wrapped along the light-cone using operators in the dual gauge theory: the open string states are constructed using defect fields. We also find supersymmetric D1 (monopoles) and D3 (giant gravitons) branes that wrap only one of the light-cone directions. These correspond to non-perturbative states in the dual gauge theory.
Ad Hoc Curriculum Implementation Working Group Ad Hoc Working Group
Brown, Sally
Ad Hoc Curriculum Implementation Working Group MINUTES Ad Hoc Working Group 4 December 2002 Friedman on her visit next week. ONE CURRICULUM OR TWO? Information presented by Trudeau shows that PSE and other programs cannot be merged into a single curriculum. The Faculty Senate website states
Ultraviolet asymptotics for quasiperiodic AdS_4 perturbations
Ben Craps; Oleg Evnin; Puttarak Jai-akson; Joris Vanhoof
2015-09-04T23:59:59.000Z
Spherically symmetric perturbations in AdS-scalar field systems of small amplitude epsilon approximately periodic on time scales of order 1/epsilon^2 (in the sense that no significant transfer of energy between the AdS normal modes occurs) have played an important role in considerations of AdS stability. They are seen as anchors of stability islands where collapse of small perturbations to black holes does not occur. (This collapse, if it happens, typically develops on time scales of the order 1/epsilon^2.) We construct an analytic treatment of the frequency spectra of such quasiperiodic perturbations, paying special attention to the large frequency asymptotics. For the case of a self-interacting phi^4 scalar field in a non-dynamical AdS background, we arrive at a fairly complete analytic picture involving quasiperiodic spectra with an exponential suppression modulated by a power law at large mode numbers. For the case of dynamical gravity, the structure of the large frequency asymptotics is more complicated. We give analytic explanations for the general qualitative features of quasiperiodic solutions localized around a single mode, in close parallel to our discussion of the probe scalar field, and find numerical evidence for logarithmic modulations in the gravitational quasiperiodic spectra existing on top of the formulas previously reported in the literature.
Jet Quenching via Gravitational Radiation in Thermal AdS
Edward Shuryak; Ho-Ung Yee; Ismail Zahed
2011-10-04T23:59:59.000Z
We argue that classical bulk gravitational radiation effects in AdS/CFT, previously ignored because of their subleading nature in the 1/Nc-expansion, are magnified by powers of large Lorentz factors gamma for ultrarelativistic jets, thereby dominating other forms of jet energy loss in holography at finite temperature. We make use of the induced gravitational self-force in thermal AdS5 to estimate its effects. In a thermal medium, relativistic jets may loose most of their energy through longitudinal drag caused by the energy accumulated in their nearby field as they zip through the strongly coupled plasma.
Li, Lian
with Idiopathic Parkinson's and Alzheimer's Diseases* Received for publication, December 23, 2003 Published, JBC of Texas Health Science Center, San Antonio, Texas 78229 Alzheimer's disease (AD) and Parkinson's disease's disease (AD)1 and Parkinson's disease (PD) are the two most common neurodegenerative disorders in humans
Emergent quantum criticality, Fermi surfaces, and AdS2
Thomas Faulkner; Hong Liu; John McGreevy; David Vegh
2011-10-30T23:59:59.000Z
Gravity solutions dual to d-dimensional field theories at finite charge density have a near-horizon region which is AdS_2 x R^{d-1}. The scale invariance of the AdS_2 region implies that at low energies the dual field theory exhibits emergent quantum critical behavior controlled by a (0+1)-dimensional CFT. This interpretation sheds light on recently-discovered holographic descriptions of Fermi surfaces, allowing an analytic understanding of their low-energy excitations. For example, the scaling behavior near the Fermi surfaces is determined by conformal dimensions in the emergent IR CFT. In particular, when the operator is marginal in the IR CFT, the corresponding spectral function is precisely of the "Marginal Fermi Liquid" form, postulated to describe the optimally doped cuprates.
Perturbative entanglement thermodynamics for AdS spacetime: Renormalization
Rohit Mishra; Harvendra Singh
2015-07-14T23:59:59.000Z
We study the effect of charged excitations in the AdS spacetime on the first law of entanglement thermodynamics. It is found that `boosted' AdS black holes give rise to a more general form of first law which includes chemical potential and charge density. To obtain this result we have to resort to a second order perturbative calculation of entanglement entropy for small size subsystems. At first order the form of entanglement law remains unchanged even in the presence of charged excitations. But the thermodynamic quantities have to be appropriately `renormalized' at the second order due to the corrections. We work in the perturbative regime where $T_{thermal}\\ll T_E$.
AdS_6 solutions of type II supergravity
Fabio Apruzzi; Marco Fazzi; Achilleas Passias; Dario Rosa; Alessandro Tomasiello
2015-04-03T23:59:59.000Z
Very few AdS_6 x M_4 supersymmetric solutions are known: one in massive IIA, and two IIB solutions dual to it. The IIA solution is known to be unique; in this paper, we use the pure spinor approach to give a classification for IIB supergravity. We reduce the problem to two PDEs on a two-dimensional space Sigma. M_4 is then a fibration of S^2 over Sigma; the metric and fluxes are completely determined in terms of the solution to the PDEs. The results seem likely to accommodate near-horizon limits of (p,q)-fivebrane webs studied in the literature as a source of CFT_5's. We also show that there are no AdS_6 solutions in eleven-dimensional supergravity.
Perturbative entanglement thermodynamics for AdS spacetime: Renormalization
Mishra, Rohit
2015-01-01T23:59:59.000Z
We study the effect of charged excitations in the AdS spacetime on the first law of entanglement thermodynamics. It is found that `boosted' AdS black holes give rise to a more general form of first law which includes chemical potential and charge density. To obtain this result we have to resort to a second order perturbative calculation of entanglement entropy for small size subsystems. At first order the form of entanglement law remains unchanged even in the presence of charged excitations. But the thermodynamic quantities have to be appropriately `renormalized' at the second order due to the corrections. We work in the perturbative regime where $T_{thermal}\\ll T_E$.
Quintessence and effective AdS brane geometries
K. Priyabrat Pandey; Abhishek K. Singh; Sunita Singh; Supriya Kar
2014-07-25T23:59:59.000Z
A geometric torsion dynamics leading to an effective curvature in a second order formalism on a D4-brane is revisited with a renewed interest. We obtain two effective $AdS_4$ brane geometries on a vacuum created pair of $(D{\\bar D})_3$-brane. One of them is shown to describe an AdS Schwarzschild spinning black hole and the other is shown to describe a spinning black hole bound state. It is argued that a D-instanton in a vacuum created anti D3-brane within a pair may describe a quintessence. It may seen to incorporate a varying vacuum energy density in a brane universe. We consider the effective curvature scalar on $S^1\\times S^1$ to analyze torsion-less geometries on a vacuum created pair of $(D{\\bar D})_2$-brane. The emergent $AdS_3$ brane is shown to describe a Schwarzschild and a Reissner-Nordstrom (RN) geometries in presence of extra dimension(s).
CNS Infiltration of Peripheral Immune Cells: D-Day for Neurodegenerative Disease?
Rezai-Zadeh, Kavon; Gate, David; Town, Terrence
2009-01-01T23:59:59.000Z
encephalitis . multiple sclerosis . experimental autoimmunedisease (AD), multiple sclerosis (MS), and Parkinson'sdemyelinating disease multiple sclerosis) and may also be
Buehler, Susan Kyung; Buehler, Susan Kyung
2012-01-01T23:59:59.000Z
Medicine, 52(3-4), 208-212. O'Leary, D. H. , Polak, J. F. ,A. , Sidney, S. , & O'Leary, D. H. (2010). Segment-specificand myocardial infarction (O'Leary et al. , 1999). Moreover,
Social Cognition in Frontotemporal Dementia, Motor Neurone Disease, and Alzheimer's Disease
Oliver, Lindsay
2011-11-23T23:59:59.000Z
The orbitofrontal cortex and ventromedial prefrontal cortex have been implicated in many aspects of social cognition, and conditions that affect these regions are thereby accompanied by deficits in interpersonal behaviour. ...
Quantum strings in AdS5 x S5 and AdS/CFT duality
A. A. Tseytlin
2009-09-23T23:59:59.000Z
We review some recent progress in understanding the spectrum of energies/dimensions of strings/operators in AdS5 x S5 -- planar N=4 super Yang-Mills correspondence. We consider leading strong coupling corrections to the energy of lightest massive string modes in AdS5 x S5, which should be dual to members of the Konishi operator multiplet in the SYM theory. This determines the general structure of strong-coupling expansion of the anomalous dimension of the Konishi operator. Following arXiv:0906.4294 we use 1-loop results for semiclassical string states to extract information about the leading coefficients in this expansion.
Entanglement Entropy and Duality in AdS(4)
Ioannis Bakas; Georgios Pastras
2015-04-30T23:59:59.000Z
Small variations of the entanglement entropy \\delta S and the expectation value of the modular Hamiltonian \\delta E are computed holographically for circular entangling curves in the boundary of AdS(4), using gravitational perturbations with general boundary conditions in spherical coordinates. Agreement with the first law of thermodynamics, \\delta S = \\delta E, requires that the line element of the entangling curve remains constant. In this context, we also find a manifestation of electric-magnetic duality for the entanglement entropy and the corresponding modular Hamiltonian, following from the holographic energy-momentum/Cotton tensor duality.
Entanglement Entropy and Duality in AdS(4)
Bakas, Ioannis
2015-01-01T23:59:59.000Z
Small variations of the entanglement entropy \\delta S and the expectation value of the modular Hamiltonian \\delta E are computed holographically for circular entangling curves in the boundary of AdS(4), using gravitational perturbations with general boundary conditions in spherical coordinates. Agreement with the first law of thermodynamics, \\delta S = \\delta E, requires that the line element of the entangling curve remains constant. In this context, we also find a manifestation of electric-magnetic duality for the entanglement entropy and the corresponding modular Hamiltonian, following from the holographic energy-momentum/Cotton tensor duality.
AdS Chern-Simons Gravity induces Conformal Gravity
Rodrigo Aros; Danilo E. Diaz
2013-12-25T23:59:59.000Z
The leitmotif of this paper is the question of whether four- and higher even-dimensional Conformal Gravities do have a Chern-Simons pedigree. We show that Weyl gravity can be obtained as dimensional reduction of a five-dimensional Chern-Simons action for a suitable (gauged-fixed, tractor-like) five-dimensional AdS connection. The gauge-fixing and dimensional reduction program admits a readily generalization to higher dimensions for the case of certain conformal gravities obtained by contractions of the Weyl tensor.
Thermal Fluctuations in a Charged AdS Black Hole
Pourhassan, B
2015-01-01T23:59:59.000Z
In this paper, we will analyze the effects of thermal fluctuations on a charged AdS black hole. This will be done by analyzing the corrections to black hole thermodynamics due to these thermal fluctuations. We will demonstrate that the entropy of this black hole get corrected by logarithmic term. We will also calculate other corrections to other important thermodynamic quantities for this black hole. Finally, we will use the corrected value of the specific heat to analyze the phase transition in this system.
Thermal Fluctuations in a Charged AdS Black Hole
B. Pourhassan; Mir Faizal
2015-08-12T23:59:59.000Z
In this paper, we will analyze the effects of thermal fluctuations on a charged AdS black hole. This will be done by analyzing the corrections to black hole thermodynamics due to these thermal fluctuations. We will demonstrate that the entropy of this black hole get corrected by logarithmic term. We will also calculate other corrections to other important thermodynamic quantities for this black hole. Finally, we will use the corrected value of the specific heat to analyze the phase transition in this system.
Vascular pathology in the aged human brain
Grinberg, Lea Tenenholz; Thal, Dietmar Rudolf
2010-01-01T23:59:59.000Z
vascular pathology, and the AD brain. Neurology 65: 259–265brospinal ?uid from the rat brain. Acta Neuropathol (Berl)and Alzheimer’s disease in the brains of elderly individuals
Nanofluidic biosensing for beta-amyloid detection
Chou, I-Hsien
2009-05-15T23:59:59.000Z
A nanofluidic biosensor using surface-enhanced Raman scattering (SERS) was developed to detect the ?-amyloid (A?) protein, one of the biomarkers of Alzheimer’s disease (AD). Recent studies have indicated that investigating changes in relative...
Strings on AdS Wormholes and Nonsingular Black Holes
H. Lu; Justin F. Vazquez-Poritz; Zhibai Zhang
2014-10-22T23:59:59.000Z
Certain AdS black holes in the STU model can be conformally scaled to wormhole and black hole solutions of an f(R) type theory which have two asymptotically AdS regions and are completely free of curvature singularities. While there is a delta-function source for the dilaton, classical string probes are not sensitive to this singularity. If the AdS/CFT correspondence can be applied in this context, then the wormhole background describes a phase in which two copies of a conformal field theory interact with each other, whereas the nonsingular black hole describes entangled states. By studying the behavior of open strings on these backgrounds, we extract a number of features of the quarks and anti-quarks that live in the field theories. In the interacting phase, we find that there is a maximum speed with which the quarks can move without losing energy, beyond which energy is transferred from a quark in one field theory to a quark in the other. We also compute the rate at which moving quarks within entangled states lose energy to the two surrounding plasmas. While a quark-antiquark pair within a single field theory exhibits Coulomb interaction for small separation, a quark in one field theory exhibits spring-like confinement with an anti-quark in the other field theory. For the entangled states, we study how the quark-antiquark screening length depends on temperature and chemical potential. In the interacting phase of the two field theories, a quadruplet made up of one quark-antiquark pair in each field theory can undergo transitions involving how the quarks and antiquarks are paired in terms of the screening.
Marco M. Caldarelli; Joan Camps; Blaise Goutéraux; Kostas Skenderis
2014-04-18T23:59:59.000Z
We present a comprehensive analysis of the AdS/Ricci-flat correspondence, a map between a class of asymptotically locally AdS spacetimes and a class of Ricci-flat spacetimes. We provide a detailed derivation of the map, discuss a number of extensions and apply it to a number of important examples, such as AdS on a torus, AdS black branes and fluids/gravity metrics. In particular, the correspondence links the hydrodynamic regime of asymptotically flat black $p$-branes or the Rindler fluid with that of AdS. It implies that this class of Ricci-flat spacetimes inherits from AdS a generalized conformal symmetry and has a holographic structure. We initiate the discussion of holography by analyzing how the map acts on boundary conditions and holographic 2-point functions.
Adding Value to Agricultural Products
Anderson, David P.; Hanselka, Daniel
2009-06-01T23:59:59.000Z
and some of the viscera into menudo or tripas. Booker Packing Company, Caviness Packing Company and J&B Foods are some of the compa- nies adding value to meat successfully in spite of processing costs. A recent survey of such companies indicated...
Neuronal Protection by a Novel C-terminal Hsp90 Modulator
Menchen, Heather Ann
2012-08-31T23:59:59.000Z
Alzheimer's disease (AD), like most neurodegenerative disorders, is characterized by accumulation of misfolded and aggregated proteins, indicating that the protein quality control machinery is compromised. Enhancing the ...
Statistical shape analysis of neuroanatomical structures based on spherical wavelet transformation
Yu, Peng, Ph. D. Massachusetts Institute of Technology
2008-01-01T23:59:59.000Z
Evidence suggests that morphological changes of neuroanatomical structures may reflect abnormalities in neurodevelopment, or relate to a variety of disorders, such as schizophrenia and Alzheimer's disease (AD). Advances ...
Matching of correlators in AdS_3/CFT_2
Marika Taylor
2007-09-12T23:59:59.000Z
Recently exact agreement has been found between three-point correlators of chiral operators computed in string theory on AdS_3 x S^3 x T^4 with NS-NS flux and those computed in the symmetric orbifold CFT. However, it has also been shown that these correlators disagree with those computed in supergravity, under any identification of single particle operators which respects the symmetries. In this note we resolve this disagreement: the key point is that mixings with multi-particle operators are not suppressed even at large N in extremal correlators. Allowing for such mixings, orbifold/string theory operators and supergravity operators can be matched such that both non-extremal and extremal three point functions agree, giving further evidence for the non-renormalization of the chiral ring.
The Analytic Bootstrap and AdS Superhorizon Locality
A. Liam Fitzpatrick; Jared Kaplan; David Poland; David Simmons-Duffin
2013-01-24T23:59:59.000Z
We take an analytic approach to the CFT bootstrap, studying the 4-pt correlators of d > 2 dimensional CFTs in an Eikonal-type limit, where the conformal cross ratios satisfy |u| 2\\Delta_\\phi + 2n for each integer n as l -> infinity. We show how the rate of approach is controlled by the twist and OPE coefficient of the leading twist operator in the \\phi x \\phi OPE, and we discuss SCFTs and the 3d Ising Model as examples. Additionally, we show that the OPE coefficients of other large spin operators appearing in the OPE are bounded as l -> infinity. We interpret these results as a statement about superhorizon locality in AdS for general CFTs.
AdS Bubbles, E$p$-branes and Entanglement
Harvendra Singh
2014-10-15T23:59:59.000Z
The AdS-bubble solutions interestingly mimic Schr\\"odinger-like geometries when expressed in light-cone coordinates. These D$p$ bubble vacuas exhibit asymmetric scaling property with a negative dynamical exponent of time $a0$ in type II* super-strings. We obtain an expression for the entanglement entropy for `bubble E3-branes'. It is argued that the entropy from E3-bubbles has to be the lowest.
Crompton, Catherine
2011-06-29T23:59:59.000Z
This between groups experimental design study explores the relationship between executive functioning, dual task ability and socio-behavioural performance in healthy ageing. Case study methodology was also used to explore ...
Islands of stability and recurrence times in AdS
Stephen R. Green; Antoine Maillard; Luis Lehner; Steven L. Liebling
2015-08-27T23:59:59.000Z
We study the stability of anti-de Sitter (AdS) spacetime to spherically symmetric perturbations of a real scalar field in general relativity. Further, we work within the context of the "two time framework" (TTF) approximation, which describes the leading nonlinear effects for small amplitude perturbations, and is therefore suitable for studying the weakly turbulent instability of AdS---including both collapsing and non-collapsing solutions. We have previously identified a class of quasi-periodic (QP) solutions to the TTF equations, and in this work we analyze their stability. We show that there exist several families of QP solutions that are stable to linear order, and we argue that these solutions represent islands of stability in TTF. We extract the eigenmodes of small oscillations about QP solutions, and we use them to predict approximate recurrence times for generic non-collapsing initial data in the full (non-TTF) system. Alternatively, when sufficient energy is driven to high-frequency modes, as occurs for initial data far from a QP solution, the TTF description breaks down as an approximation to the full system. Depending on the higher order dynamics of the full system, this often signals an imminent collapse to a black hole.
Islands of stability and recurrence times in AdS
Green, Stephen R; Lehner, Luis; Liebling, Steven L
2015-01-01T23:59:59.000Z
We study the stability of anti-de Sitter (AdS) spacetime to spherically symmetric perturbations of a real scalar field in general relativity. Further, we work within the context of the "two time framework" (TTF) approximation, which describes the leading nonlinear effects for small amplitude perturbations, and is therefore suitable for studying the weakly turbulent instability of AdS---including both collapsing and non-collapsing solutions. We have previously identified a class of quasi-periodic (QP) solutions to the TTF equations, and in this work we analyze their stability. We show that there exist several families of QP solutions that are stable to linear order, and we argue that these solutions represent islands of stability in TTF. We extract the eigenmodes of small oscillations about QP solutions, and we use them to predict approximate recurrence times for generic non-collapsing initial data in the full (non-TTF) system. Alternatively, when sufficient energy is driven to high-frequency modes, as occurs ...
Islands of stability and recurrence times in AdS
Stephen R. Green; Antoine Maillard; Luis Lehner; Steven L. Liebling
2015-07-29T23:59:59.000Z
We study the stability of anti-de Sitter (AdS) spacetime to spherically symmetric perturbations of a real scalar field in general relativity. Further, we work within the context of the "two time framework" (TTF) approximation, which describes the leading nonlinear effects for small amplitude perturbations, and is therefore suitable for studying the weakly turbulent instability of AdS---including both collapsing and non-collapsing solutions. We have previously identified a class of quasi-periodic (QP) solutions to the TTF equations, and in this work we analyze their stability. We show that there exist several families of QP solutions that are stable to linear order, and we argue that these solutions represent islands of stability in TTF. We extract the eigenmodes of small oscillations about QP solutions, and we use them to predict approximate recurrence times for generic non-collapsing initial data in the full (non-TTF) system. Alternatively, when sufficient energy is driven to high-frequency modes, as occurs for initial data far from a QP solution, the TTF description breaks down as an approximation to the full system. Depending on the higher order dynamics of the full system, this often signals an imminent collapse to a black hole.
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Light-cone AdS/CFT-adapted approach to AdS fields/currents, shadows, and conformal fields
R. R. Metsaev
2015-07-23T23:59:59.000Z
Light-cone gauge formulation of fields in AdS space and conformal field theory in flat space adapted for the study of AdS/CFT correspondence is developed. Arbitrary spin mixed-symmetry fields in AdS space and arbitrary spin mixed-symmetry currents, shadows, and conformal fields in flat space are considered on an equal footing. For the massless and massive fields in AdS and the conformal fields in flat space, simple light-cone gauge actions leading to decoupled equations of motion are found. For the currents and shadows, simple expressions for all 2-point functions are also found. We demonstrate that representation of conformal algebra generators on space of currents, shadows, and conformal fields can be built in terms of spin operators entering the light-cone gauge formulation of AdS fields. This considerably simplifies the study of AdS/CFT correspondence. Light-cone gauge actions for totally symmetric arbitrary spin long conformal fields in flat space are presented. We apply our approach to the study of totally antisymmetric (one-column) and mixed-symmetry (two-column) fields in AdS space and currents, shadows, and conformal fields in flat space.
AEI-2008-085 The Classical Exchange Algebra of AdS5 S5
Paris-Sud XI, Université de
AEI-2008-085 The Classical Exchange Algebra of AdS5 × S5 String Theory Marc Magro Universit´e de matrix of AdS5× S5 string theory in the Green-Schwarz formulation is determined by using a first the pure spinor description of AdS5 × S5 string theory. These results are compared to the one obtained by A
On Rotating and Oscillating Four-Spin Strings in AdS5 X S5
Kamal L. Panigrahi; Pabitra M. Pradhan
2012-10-26T23:59:59.000Z
We study rigidly rotating strings in AdS5 X S5 background with one spin along AdS5 and three angular momenta along S5. We find dispersion relations among various charges and interpret them as giant magnon and spiky string solutions in various limits. Further we present an example of oscillating string which oscillates in the radial direction of the AdS5 and at the same time rotates in S5.
On Rotating and Oscillating Four-Spin Strings in AdS5 X S5
Panigrahi, Kamal L
2012-01-01T23:59:59.000Z
We study rigidly rotating strings in AdS5 X S5 background with one spin along AdS5 and three angular momenta along S5. We find dispersion relations among various charges and interpret them as giant magnon and spiky string solutions in various limits. Further we present an example of oscillating string which oscillates in the radial direction of the AdS5 and at the same time rotates in S5.
Longitudinal Analysis of Android Ad Library Permissions
Wallach, Dan
Longitudinal Analysis of Android Ad Library Permissions Theodore Book, Adam Pridgen, Dan S. Wallach in the behavior of Android ad libraries. Taking a sample of 114,000 apps, we extract and classify their ad particular risks to user privacy and security. I. INTRODUCTION The Android operating system is one
The different phases of hairy black holes in AdS5 space
Gaston Giribet; Andres Goya; Julio Oliva
2014-12-31T23:59:59.000Z
We investigate the thermodynamics of hairy black holes in asymptotically Anti-de Sitter (AdS) space, including backreaction. Resorting to the Euclidean path integral approach, we show that matter conformally coupled to Einstein gravity in five dimensions may exhibit a phase transition whose endpoint turns out to be a hairy black hole in AdS5 space. The scalar field configuration happens to be regular everywhere outside and on the horizon, and behaves asymptotically in such a way that respects the AdS boundary conditions that are relevant for AdS/CFT. The theory presents other peculiar features in the ultraviolet, like the existence of black holes with arbitrarily low temperature in AdS5. This provides a simple setup in which the fully backreacting problem of a hair forming in AdS at certain critical temperature can be solved analytically.
The different phases of hairy black holes in AdS5 space
Giribet, Gaston; Oliva, Julio
2015-01-01T23:59:59.000Z
We investigate the thermodynamics of hairy black holes in asymptotically Anti-de Sitter (AdS) space, including backreaction. Resorting to the Euclidean path integral approach, we show that matter conformally coupled to Einstein gravity in five dimensions may exhibit a phase transition whose endpoint turns out to be a hairy black hole in AdS5 space. The scalar field configuration happens to be regular everywhere outside and on the horizon, and behaves asymptotically in such a way that respects the AdS boundary conditions that are relevant for AdS/CFT. The theory presents other peculiar features in the ultraviolet, like the existence of black holes with arbitrarily low temperature in AdS5. This provides a simple setup in which the fully backreacting problem of a hair forming in AdS at certain critical temperature can be solved analytically.
Tunneling between the giant gravitons in AdS5 x S5
Julian Lee
2001-04-05T23:59:59.000Z
I consider the giant gravitons in AdS5 x S5. By numerical simulation, I show a strong indication that there is no instanton solution describing the direct tunneling between the giant graviton in the S5 and its dual counterpart in the AdS5. I argue that it supports the supersymmetry breaking scenario suggested in hep-th/0008015
LWR (Light Water Reactor) power plant simulations using the AD10 and AD100 systems
Wulff, W.; Cheng, H.S.; Chien, C.J.; Jang, J.Y.; Lin, H.C.; Mallen, A.N.; Wang, S.J. (Brookhaven National Lab., Upton, NY (USA); Institute of Nuclear Energy Research, Lung-Tan (Taiwan); Tawian Power Co., Taipei (Taiwan); Brookhaven National Lab., Upton, NY (USA); Institute of Nuclear Energy Research, Lung-Tan (Taiwan))
1989-01-01T23:59:59.000Z
Boiling (BWR) and Pressurized (PWR) Water Reactor Power Plants are being simulated at BNL with the AD10 and AD100 Peripheral Processor Systems. The AD10 system has been used for BWR simulations since 1984 for safety analyses, emergency training and optimization studies. BWR simulation capabilities have been implemented recently on the AD100 system and PWR simulation capabilities are currently being developed under the auspices of international cooperation. Modeling and simulation methods are presented with emphasis on the simulation of the Nuclear Steam Supply System. Results are presented for BWR simulation and performance characteristics are compared of the AD10 and AD100 systems. It will be shown that the AD100 simulates two times faster than two AD10 processors operating in parallel and that the computing capacity of one AD100 (with FMU processor) is twice as large as that of two AD10 processors. 9 refs., 5 figs., 1 tab.
Perentos, Nicholas; Martins, Amadeu Q.; Watson, Thomas C.; Bartsch, Ullrich; Mitchell, Nadia L.; Palmer, David N.; Jones, Matthew W.; Morton, A. Jennifer
2015-02-27T23:59:59.000Z
an isoflur- ane/oxygen/nitrous mixture delivered through a Manley venti- lator (stroke volume 300ml and ventilation rate 15–20/min). Isoflurane was maintained at 2–3%, end-tidal CO2 at 25–30mmHg and mean arterial blood pressure at 70–90mmHg. Intravenous... J, Shoemaker JK, Martin RE. Swallowing dysfunction and autonomic nervous system dysfunction in Alzheimer’s disease: a scoping review of the evidence. J Am Geriatr Soc 2013; 61: 2203–13. Allison T, Cicchetti DV. Sleep in mammals: ecological...
Personalized medicine strategies for managing patients with Parkinsonism and cognitive deficits
Wurtman, Richard
and behavioral symptoms may arise from Parkinson's disease [PD] per se, but they can also characterize Lewy Body dementia [LBD] or concurrent Parkinson's and Alzheimer's diseases [PD & AD]. Abnormalities of both movement with parkinsonism, Alzheimer's disease and Huntington's disease (HD) and by the variety of regional and temporal
University Policy No.: AD2210 Classification: Administration
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University Policy No.: AD2210 Classification: Administration FIELDWORK AND INTERNATIONAL: includes all University of Victoria administrators, faculty, staff, and students while such individuals
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University Policy No.: AD2215 Classification: Administration Approving Authority: Board Review: 1. This statement applies to the policies and administration of trademarks registered
University Policy No.: AD2530 Classification: Administration
Victoria, University of
University Policy No.: AD2530 Classification: Administration PHOTOCOPY AND FACSIMILE (FAX may be obtained through library managed machines or through the use of personal accounts. 1
Amador, Jose; Berry, Robert W.; Frederiksen, Richard A.; Horne, C. Wendell; Thames, Walter H.; Toler, Robert W.
1969-01-01T23:59:59.000Z
Foreign animal disease can cause serious damage to the United States (US) agricultural sector and foot-and-mouth disease (FMD), in particular, poses a serious threat. FMD causes death and reduced fecundity in infected ...
Distributed services for mobile ad hoc networks
Cao, Guangtong
2005-11-01T23:59:59.000Z
A mobile ad hoc network consists of certain nodes that communicate only through wireless medium and can move arbitrarily. The key feature of a mobile ad hoc network is the mobility of the nodes. Because of the mobility, communication links form...
Distributed services for mobile ad hoc networks
Cao, Guangtong
2005-11-01T23:59:59.000Z
A mobile ad hoc network consists of certain nodes that communicate only through wireless medium and can move arbitrarily. The key feature of a mobile ad hoc network is the mobility of the nodes. Because of the mobility, communication links form...
Splitting of Folded Strings in AdS_4*CP^3
Jun-Bao Wu
2012-08-04T23:59:59.000Z
We study classically splitting of two kinds of folded string solutions in AdS_4*CP^3. Conserved charges of the produced fragments are computed for each case. We find interesting patterns among these conserved charges.
Duality invariance of $s \\ge 3/2$ fermions in AdS
S. Deser; D. Seminara
2014-09-11T23:59:59.000Z
We show that in D=4 AdS, $s\\ge 3/2$ partially massless (PM) fermions retain the duality invariances of their flat space massless counterparts. They have tuned ratios $ {m^2}/{M^2}\
Han, Bing; Chen, Xue-wen; Talebizadeh, Zohreh; Xu, Hua
2012-12-17T23:59:59.000Z
(Suppl 3):S14 http://www.biomedcentral.com/1752-0509/6/S3/S14 © 2012 Han et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2...) heuristic search method can solve the classical XOR (Exclusive or) pro- blem [14]. We apply the EpiBN method to simulated datasets based on four disease models and three real datasets: Age-related Macular Degeneration (AMD) dataset, late-onset Alzheimer...
Freivogel, Ben; /Stanford U., Phys. Dept. /LBL, Berkeley; Hubeny, Veronika E.; /LBL, Berkeley /Durham U., Dept. of Math.; Maloney, Alexander; /Stanford U., Phys. Dept.; Myers, Rob; /Perimeter Inst. Theor. Phys. /Waterloo U.; Rangamani, Mukund; /LBL, Berkeley /Durham U., Dept. of Math.; Shenker, Stephen; /Stanford U., Phys. Dept.
2005-10-07T23:59:59.000Z
We study the realization of inflation within the AdS/CFT correspondence. We assume the existence of a string landscape containing at least one stable AdS vacuum and a (nearby) metastable de Sitter state. Standard arguments imply that the bulk physics in the vicinity of the AdS minimum is described by a boundary CFT. We argue that large enough bubbles of the dS phase, including those able to inflate, are described by mixed states in the CFT. Inflating degrees of freedom are traced over and do not appear explicitly in the boundary description. They nevertheless leave a distinct imprint on the mixed state. Analytic continuation allows us, in principle, to recover a large amount of nonperturbatively defined information about the inflating regime. Our work also shows that no scattering process can create an inflating region, even by quantum tunneling, since a pure state can never evolve into a mixed state under unitary evolution.We study the realization of inflation within the AdS/CFT correspondence. We assume the existence of a string landscape containing at least one stable AdS vacuum and a (nearby) metastable de Sitter state. Standard arguments imply that the bulk physics in the vicinity of the AdS minimum is described by a boundary CFT. We argue that large enough bubbles of the dS phase, including those able to inflate, are described by mixed states in the CFT. Inflating degrees of freedom are traced over and do not appear explicitly in the boundary description. They nevertheless leave a distinct imprint on the mixed state. Analytic continuation allows us, in principle, to recover a large amount of nonperturbatively defined information about the inflating regime. Our work also shows that no scattering process can create an inflating region, even by quantum tunneling, since a pure state can never evolve into a mixed state under unitary evolution.
Information Regarding MENINGOCOCCAL DISEASE
. Meningococcal disease is a serious disease, caused by bacteria. Meningococcal disease is a contagious
The Tetrahedron Zamolodchikov Algebra and the AdS5 x S5 S-matrix
Mitev, Vladimir; Tsuboi, Zengo
2012-01-01T23:59:59.000Z
The S-matrix of the AdS5 x S5 string theory is a tensor product of two centrally extended su(2|2) S-matrices, each of which is related to the R-matrix of the Hubbard model. The R-matrix of the Hubbard model was first found by Shastry, who ingeniously exploited the fact that, for zero coupling, the Hubbard model can be decomposed into two XX models. In this article, we review and clarify this construction from the AdS/CFT perspective and investigate the implications this has for the AdS5 x S5 S-matrix.
The Tetrahedron Zamolodchikov Algebra and the AdS5 x S5 S-matrix
Vladimir Mitev; Matthias Staudacher; Zengo Tsuboi
2012-10-08T23:59:59.000Z
The S-matrix of the AdS5 x S5 string theory is a tensor product of two centrally extended su(2|2) S-matrices, each of which is related to the R-matrix of the Hubbard model. The R-matrix of the Hubbard model was first found by Shastry, who ingeniously exploited the fact that, for zero coupling, the Hubbard model can be decomposed into two XX models. In this article, we review and clarify this construction from the AdS/CFT perspective and investigate the implications this has for the AdS5 x S5 S-matrix.
Higher spins in AdS_5 at one loop: vacuum energy, boundary conformal anomalies and AdS/CFT
M. Beccaria; A. A. Tseytlin
2014-11-18T23:59:59.000Z
We consider general-symmetry higher spin fields in AdS_5 and derive expressions for their one-loop corrections to vacuum energy E and the associated 4d boundary conformal anomaly a-coefficient. We a propose a similar expression for the second conformal anomaly c-coefficient. We show that all the three quantities (E, a, c) computed for N=8 gauged 5d supergravity are -1/2 of the values for N=4 conformal 4d supergravity and also twice the values for N=4 Maxwell multiplet. This gives 5d derivation of the fact that the system of N=4 conformal supergravity and four N=4 Maxwell multiplets is anomaly free. The values of (E, a, c) for the states at level p of Kaluza-Klein tower of 10d type IIB supergravity compactified on S^5 turn out to be equal to those for p copies of N=4 Maxwell multiplets. This may be related to the fact that these states appear in the tensor product of p superdoubletons. Under a natural regularization of the sum over p, the full 10d supergravity contribution is then minus that of the Maxwell multiplet, in agreement with the standard adjoint AdS/CFT duality (SU(n) SYM contribution is n^2-1 of one Maxwell multiplet). We also verify the matching of (E, a, c) for spin 0 and 1/2 boundary theory cases of vectorial AdS/CFT duality. The consistency conditions for vectorial AdS/CFT turn out to be equivalent to the cancellation of anomalies in the closely related 4d conformal higher spin theories. In addition, we study novel example of vectorial AdS/CFT duality when the boundary theory is described by free spin 1 fields and is dual to a particular higher spin theory in AdS_5 containing fields in mixed-symmetry representations. We also discuss its supersymmetric generalizations.
Discrete Molecular Dynamics Study of wild-type and Arctic-mutant (E22G) A16-22
Stanley, H. Eugene
- structure 2 #12;Introduction Neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson, Bethesda, MD 20892 Harvard-Partners Center for Genetics and Genomics, Brigham & Women's Hospital, Boston that amyloid -protein (A) forms assemblies with potent neurotoxic prop- erties that cause Alzheimer's disease
Distributed algorithms for mobile ad hoc networks
Malpani, Navneet
2001-01-01T23:59:59.000Z
We first present two new leader election algorithms for mobile ad hoc networks. The algorithms ensure that eventually each connected component of the topology graph has exactly one leader. The algorithms are based on a routing algorithm called TORA...
Missouri Value-Added Grant Program (Missouri)
Broader source: Energy.gov [DOE]
The Missouri Value-Added Grant Program provides grants for projects that add value to Missouri agricultural products and aid the economy of a rural community. Grant applications will be considered...
Virtual infrastructure for wireless ad hoc networks
Gilbert, Seth, 1976-
2007-01-01T23:59:59.000Z
One of the most significant challenges introduced by ad hoc networks is coping with the unpredictable deployment, uncertain reliability, and erratic communication exhibited by emerging wireless networks and devices. The ...
Jia-Lin Zhang; Rong-Gen Cai; Hongwei Yu
2015-03-03T23:59:59.000Z
We study thermodynamics and thermodynamic geometry of a five-dimensional Schwarzschild AdS black hole in $AdS_5\\times{S^5}$ spacetime by treating the cosmological constant as the number of colors in the boundary gauge theory and its conjugate quantity as the associated chemical potential. It is found that the chemical potential is always negative in the stable branch of black hole thermodynamics and it has a chance to be positive, but appears in the unstable branch. We calculate scalar curvatures of the thermodynamical Weinhold metric, Ruppeiner metric and Quevedo metric, respectively and we find that the divergence of scalar curvature is related to the divergence of specific heat with fixed chemical potential in the Weinhold metric and Ruppeiner metric, while in the Quevedo metric the divergence of scalar curvature is related to the divergence of specific heat with fixed number of colors and the vanishing of the specific heat with fixed chemical potential.
AUAARHUS UNIVERSITY Adding of attachments Financial Control
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QCD Condensates and Holographic Wilson Loops for Asymptotically AdS Spaces
Quevedo, R. Carcasses [Instituto Balseiro, Centro Atomico Bariloche, 8400 San Carlos de Bariloche (Argentina); CONICET, Rivadavia 1917, 1033 Buenos Aires (Argentina); Goity, Jose L. [Hampton University, Hampton, VA 23668 (United States); Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Trinchero, Roberto C. [Instituto Balseiro, Centro Atomico Bariloche, 8400 San Carlos de Bariloche (Argentina); CONICET, Rivadavia 1917, 1033 Buenos Aires (Argentina)
2014-02-01T23:59:59.000Z
The minimization of the Nambu-Goto (NG) action for a surface whose contour defines a circular Wilson loop of radius a placed at a finite value of the coordinate orthogonal to the border is considered. This is done for asymptotically AdS spaces. The condensates of dimension n = 2, 4, 6, 8, and 10 are calculated in terms of the coefficients in the expansion in powers of the radius a of the on-shell subtracted NG action for small a->0. The subtraction employed is such that it presents no conflict with conformal invariance in the AdS case and need not introduce an additional infrared scale for the case of confining geometries. It is shown that the UV value of the gluon condensates is universal in the sense that it only depends on the first coefficients of the difference with the AdS case.
Microstructural white matter changes in Alzheimer's disease : a diffusion tensor imaging study
Horne, Nikki Renee
2008-01-01T23:59:59.000Z
62(10), 1862-1864. Van Petten, C. (2004). Relationship42(10), 1394-1413. Van Petten, C. , Plante, E. , Davidson,regions (Raz, 2005; Van Petten et al. , 2004). This pattern
Wardak, Mirwais
2013-01-01T23:59:59.000Z
via inhalation into the lungs, direct injection into thebilateral metastasis to the lung (arrow) from a previousproduces poor images of the lung, is not able to show
Brinton, Roberta Diaz
glycolysis and citric acid cycle-driven oxidative phosphorylation and ATP generation. Data derived from, enhanced glycolysis coupled to the citric acid cycle (aerobic glycolysis), sustained and enhanced glycolysis (oxidative phosphorylation coupled to pyruvate metabolism). The enhanced aerobic glycolysis
Nutrition and Alzheimer's Disease: The Role of Folate and Vitamin B
Edmonds, Zachary V.
1999-01-01T23:59:59.000Z
Karlinsky H. Folate, vitamin B12 and cognitive impairment inH, Surron L, Ueland PU. Folate, vitamin B12, and serum totalBottiglieri T. Folate, vitamin B12, and neuropyschiatric
DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease
2013-01-01T23:59:59.000Z
al. Figure 3 Epigenetic deregulation of target genes in the3027 Figure 2 Epigenetic deregulation of target genes in
Effects of Familial Alzheimer's Disease Mutations on the Folding Nucleation of the Amyloid ?-Protein
2008-01-01T23:59:59.000Z
nucleation of amyloid ?-protein folding. Proc. Natl Acad.dynamics method for protein folding. Chem. Phys. Lett. 314,Atomic simulations of protein folding using the replica
Wardak, Mirwais
2013-01-01T23:59:59.000Z
AB, Elson LM. The human brain coloring book. 1st ed. New21. Toga AW, Mazziotta JC. Brain mapping : the systems. SanSR, Phelps ME. Imaging Brain Function with Positron Emission
DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease
2013-01-01T23:59:59.000Z
PLoS One 2009; 2: e895. Song CX, Szulwach KE, Fu Y, Dai Q,Szulwach KE, Li X, Li Y, Song CX, Wu H, Dai Q, et al. 5-hmC-cells), cerebral cortex (CX, CA1, CA3 and den- tate gyrus)
Associations between potentially modifiable risk factors and Alzheimer's disease: A Mendelian random
Østergaard, Søren D.; Mukherjee, Shubhabrata; Sharp, Stephen J.; Proitsi, Petroula; Lotta, Luca A.; Day, Felix; Perry, John R. B.; Boehme, Kevin L.; Walter, Stefan; Kauwe, John S.; Gibbons, Laura E.; Alzheimer’s Disease Genetics Consortium; The Genetic and Environmental Risk in AD Consortium; The EPIC-InterAct consortium; Larson, Eric B.; Powell, John F.; Laugenberg, Claudia; Crane, Paul K.; Wareham, Nicholas J.; Scott, Robert A.
2015-06-09T23:59:59.000Z
of insulin resistance and body fat distribution in type 2 diabetes, independently of obesity. Diabetes. 2014. 16. Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU, et al. Association analyses of 249,796 individuals reveal 18 new... with autopsy-confirmed diagnosis and no clinical diagnosis, the age at death was used for age at diagnosis. For all studies, the age used for CNEs was the age of last exam or age at death for those for whom age at exam was not available. Case and CNE subjects...
A Novel Sensitive Method of Detecting Mnemonic Decline in Mouse Model of Alzheimer's Disease
Simmons, Rebecca
2011-01-11T23:59:59.000Z
in initial discrimination learning or on the ability to ransfer this learned information to the altered context. In contrast, at 12 months of age, APP+PS1 mice learned the initial concurrent discriminations on par with iv NTgs but were impaired when... involves nondemented patients on a series of eight concurrent discriminations with each pair consisting of two objects that vary in color or two colors that vary in shape. Therefore, each pair consists of a relevant and irrelevant feature. Patients...
Sleep and markers of cardiovascular disease risk in elderly Alzheimer's caregivers
Schwartz, Jennifer
2012-01-01T23:59:59.000Z
14. Vgontzas AN, Liao D, Bixler EO, Chrousos GP, Vela-BuenoVgontzas AN, Tsigos C, Bixler EO, et al. Chronic insomnia14. Vgontzas AN, Liao D, Bixler EO, Chrousos GP, Vela-Bueno
Wardak, Mirwais
2013-01-01T23:59:59.000Z
a kinetic microarray, similar to how gene expression levelsof gene expression (1, 13-19). The tracer kinetic method is
Improving the Quality of EEG Data in Patients with Alzheimers Disease Using ICA
Cichocki, Andrzej
, electromyographic, elec- trodermal, electrovascular, and respiratory signals) may interfere with the EEG in the form
Sleep and markers of cardiovascular disease risk in elderly Alzheimer's caregivers
Schwartz, Jennifer
2012-01-01T23:59:59.000Z
30(12):645-52. Espeland MA, O'Leary D H, Terry JG, Morgan T,82(4):1230-42. Espeland MA, O'Leary D H, Terry JG, Morgan T,circulation 2004;35(9):2150-4. O'Leary DH, Polak JF, Kronmal
2011-01-01T23:59:59.000Z
and Dot Blot Assay Presence of Ab epitope in WSN-Ab 1-10 or WSN-Ab 1-7 was confirmed by Western blot using anti-Abwith rabbit polyclonal anti-WSN serum (gift of Drs. Thomas
Journal of Alzheimer's Disease 14 (2008) 235245 235 Three-Dimensional Tomographic Imaging
Dunin-Borkowski, Rafal E.
2008-01-01T23:59:59.000Z
of Denmark, DK-2800 Kongens Lyngby, Denmark e Department of Pathology, Case Western Reserve University microscopy (HR-TEM), energy dispersive X-ray (EDX) spectroscopy and electron energy-loss spectroscopy (EELS of these important roles, iron can also be toxic, with certain forms participating in the production of free radicals
Attar, Aida
2013-01-01T23:59:59.000Z
M, et al. (2010) Resveratrol selectively remodels solubleneurotrophic factor and resveratrol that is currently in3-gallate [283,284], resveratrol [285], A?42 C-terminal
UNCORRECTEDPROOF 2 3D characterization of brain atrophy in alzheimer's disease and mild
Thompson, Paul
,a Arthur W. Toga,a Natasha Lepore,a 5 Yi-Yu Chou,a Caroline Brun,a Ming-Chang Chiang,a Marina Barysheva Harvey,e John Kornak,f Norbert Schuff,g Lauren Boreta,g Gene E. Alexander,i 9 Michael W. Weiner,g,h Paul
Improved Classification of Alzheimer's Disease Data via Removal of Nuisance Variability
Koikkalainen, Juha; Polonen, Harri; Mattila, Jussi; van Gils, Mark; Soininen, Hilkka; Lotjonen, Jyrki
2012-01-01T23:59:59.000Z
Initiative 1 VTT Technical Research Centre of Finland,Tampere, Finland, 2 Department ofUniversity of Eastern Finland, Kuopio, Finland, 3 Department
Paris-Sud XI, Université de
interactions into a tetramer. Each tetramer then linked up with another tetramer as the result of longitudinal
Attar, Aida
2013-01-01T23:59:59.000Z
structural basis of protein folding and its links with human93. Dobson CM (2003) Protein folding and misfolding. NatureCM (2004) Principles of protein folding, misfolding and
Wardak, Mirwais
2013-01-01T23:59:59.000Z
of tumors with only modest increases in glucose metabolism (of tumors with only modest increases in glucose metabolism,
Microstructural white matter changes in Alzheimer's disease : a diffusion tensor imaging study
Horne, Nikki Renee
2008-01-01T23:59:59.000Z
CP = cerebral peduncles, FSRP = Framingham Stroke Riskimaging FOV field of view FSRP Framingham Stroke RiskStroke Risk Profile (FSRP, D'Agostino, Wolf, Belanger, &
DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease
2013-01-01T23:59:59.000Z
putamen, substantia nigra, hypothalamus, globus pallidus andÀ 0.90 to À 0.95), hypothalamus ( À 0.82), globus pallidus (
Habib, Lila K.
2011-01-01T23:59:59.000Z
mixed with 5% potassium ferrocyanide and incubated at roomfor 15 minutes. Potassium ferrocyanide reacts with ferriciron to form ferric ferrocyanide, a blue colloidal complex
Multiple Events Lead to Dendritic Spine Loss in Triple Transgenic Alzheimer's Disease Mice
2010-01-01T23:59:59.000Z
amyloid deposition leads to local synaptic abnormalities andMultiple Events Lead to Dendritic Spine Loss in Tripleal. (2010) Multiple Events Lead to Dendritic Spine Loss in
Multimodality MRI-based Brain Network Analysis: Applications to Genetic Risk for Alzheimer's Disease
Brown, Jesse Aaron
2013-01-01T23:59:59.000Z
Acad. Sci. U.S.A. 107, 4734–4739. Brown, J. A. , Terashima,Acad. Sci. U.S.A. 107, 4734–4739. Bondi, M.W. , Houston,
DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease
2013-01-01T23:59:59.000Z
Institute of Oncology of Asturias (IUOPA), HUCA, Universidada del Principado de Asturias (IUOPA), HUCA, Universidad de
Multimodality MRI-based Brain Network Analysis: Applications to Genetic Risk for Alzheimer's Disease
Brown, Jesse Aaron
2013-01-01T23:59:59.000Z
Robert Landick, Francisco J. Asturias, Seth A. Darst (2010).Hudmon, Francisco J. Asturias, Roger D. Kornberg (2006).advisor, Dr. Francisco Asturias. He took a chance on me when
Bonus Symmetries of N=4 Super-Yang-Mills Correlation Functions via AdS Duality
Kenneth Intriligator
1999-05-03T23:59:59.000Z
General conjectures about the SL(2,Z) modular transformation properties of N=4 super-Yang-Mills correlation functions are presented. It is shown how these modular transformation properties arise from the conjectured duality with IIB string theory on AdS_5 x S^5. We discuss in detail a prediction of the AdS duality: that N=4 field theory, in an appropriate limit, must exhibit bonus symmetries, corresponding to the enhanced symmetries of IIB string theory in its supergravity limit.
Computing and Using Metrics in the ADS
Henneken, Edwin A; Kurtz, Michael J; Grant, Carolyn S; Thompson, Donna; Luker, Jay; Chyla, Roman; Holachek, Alexandra; Murray, Stephen S
2014-01-01T23:59:59.000Z
Finding measures for research impact, be it for individuals, institutions, instruments or projects, has gained a lot of popularity. More papers than ever are being written on new impact measures, and problems with existing measures are being pointed out on a regular basis. Funding agencies require impact statistics in their reports, job candidates incorporate them in their resumes, and publication metrics have even been used in at least one recent court case. To support this need for research impact indicators, the SAO/NASA Astrophysics Data System (ADS) has developed a service which provides a broad overview of various impact measures. In this presentation we discuss how the ADS can be used to quench the thirst for impact measures. We will also discuss a couple of the lesser known indicators in the metrics overview and the main issues to be aware of when compiling publication-based metrics in the ADS, namely author name ambiguity and citation incompleteness.
Building America Expert Meeting: Key Innovations for Adding Energy...
Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site
Key Innovations for Adding Energy Efficiency to Maintenance Projects Building America Expert Meeting: Key Innovations for Adding Energy Efficiency to Maintenance Projects This...
Adaptive Scheduling in Ad Hoc and Cellular Wireless Networks
Tan, Choo Chin
2013-01-01T23:59:59.000Z
multicasting in energy-constrained wireless networks,” IEEEminimum-energy multicasting in wireless ad hoc networks,”minimum-energy multicasting in wireless ad hoc networks,” in
Addendum Added to Innovative Demonstration of Geothermal Energy...
Office of Environmental Management (EM)
Addendum Added to Innovative Demonstration of Geothermal Energy Production FOA Addendum Added to Innovative Demonstration of Geothermal Energy Production FOA July 2, 2010 - 2:13pm...
Adaptive Scheduling in Ad Hoc and Cellular Wireless Networks
Tan, Choo Chin
2013-01-01T23:59:59.000Z
organization wireless networks and wireless mobile ad-hocfor heterogeneous wireless network”, in Proc. of IEEER. Khalaf, “Ad hoc wireless networks with mobile backbones,”
Crude caffeine reduces memory impairment and amyloid b142 levels in an Alzheimer's mouse model
Lockery, Shawn
Crude caffeine reduces memory impairment and amyloid b142 levels in an Alzheimer's mouse model Yi the elderly. Crude caffeine (CC), a major by-product of the decaffeination of coffee, has potent hydrophilic
Multi-Spin Strings in AdS_4*CP^3 and its ?-deformation
Jun-Bao Wu
2013-05-31T23:59:59.000Z
In this paper, we study the multi-spin string solutions in AdS_4*CP^3 and its \\beta-deformation with real \\beta. We give various explicit solutions after some general studies. Conserved charges are computed for these explicit solutions.
Killing spinors, the adS black hole and I(ISO(2,1)) gravity
R. B. Mann; G. Papadopoulos
1996-06-12T23:59:59.000Z
We construct a supersymmetric extension of the $I\\big(ISO(2,1)\\big)$ Chern-Simons gravity and show that certain particle-like solutions and the adS black-hole solution of this theory are supersymmetric.
S-matrix for strings on $\\eta$-deformed AdS5 x S5
Arutyunov, Gleb; Frolov, Sergey
2014-01-01T23:59:59.000Z
We determine the bosonic part of the superstring sigma model Lagrangian on $\\eta$-deformed AdS5 x S5, and use it to compute the perturbative world-sheet scattering matrix of bosonic particles of the model. We then compare it with the large string tension limit of the q-deformed S-matrix and find exact agreement.
S-matrix for strings on $?$-deformed AdS5 x S5
Gleb Arutyunov; Riccardo Borsato; Sergey Frolov
2014-04-07T23:59:59.000Z
We determine the bosonic part of the superstring sigma model Lagrangian on $\\eta$-deformed AdS5 x S5, and use it to compute the perturbative world-sheet scattering matrix of bosonic particles of the model. We then compare it with the large string tension limit of the q-deformed S-matrix and find exact agreement.
Bound State Transfer Matrix for AdS5 x S5 Superstring
Gleb Arutyunov; Marius de Leeuw; Ryo Suzuki; Alessandro Torrielli
2009-09-17T23:59:59.000Z
We apply the algebraic Bethe ansatz technique to compute the eigenvalues of the transfer matrix constructed from the general bound state S-matrix of the light-cone AdS5 x S5 superstring. This allows us to verify certain conjectures on the quantum characteristic function, and to extend them to the general case.
The Thermal Scalar and Random Walks in AdS3 and BTZ
Thomas G. Mertens; Henri Verschelde; Valentin I. Zakharov
2014-07-08T23:59:59.000Z
We analyze near-Hagedorn thermodynamics of strings in the WZW $AdS_3$ model. We compute the thermal spectrum of all primaries and find the thermal scalar explicitly in the string spectrum using CFT twist techniques. Then we use the link to the Euclidean WZW BTZ black hole and write down the Euclidean BTZ spectrum. We give a Hamiltonian interpretation of the thermal partition function of angular orbifolds where we find a reappearance of discrete states that dominate the partition function. Using these results, we discuss the nature of the thermal scalar in the WZW BTZ model. As a slight generalization of the angular orbifolds, we discuss the $AdS_3$ string gas with a non-zero chemical potential corresponding to angular momentum around the spatial cigar. For this model as well, we determine the thermal spectrum and the Hagedorn temperature as a function of chemical potential. Finally the nature of $\\alpha'$ corrections to the $AdS_3$ thermal scalar action is analyzed and we find the random walk behavior of highly excited strings in this particular $AdS_3$ background.
Holographic Thermalization, stability of AdS, and the Fermi-Pasta-Ulam-Tsingou paradox
Venkat Balasubramanian; Alex Buchel; Stephen R. Green; Luis Lehner; Steven L. Liebling
2014-06-16T23:59:59.000Z
For a real massless scalar field in general relativity with a negative cosmological constant, we uncover a large class of spherically symmetric initial conditions that are close to AdS, but whose numerical evolution does not result in black hole formation. According to the AdS/CFT dictionary, these bulk solutions are dual to states of a strongly interacting boundary CFT that fail to thermalize at late times. Furthermore, as these states are not stationary, they define dynamical CFT configurations that do not equilibrate. We develop a two-timescale perturbative formalism that captures both direct and inverse cascades of energy and agrees with our fully nonlinear evolutions in the appropriate regime. We also show that this formalism admits a large class of quasi-periodic solutions. Finally, we demonstrate a striking parallel between the dynamics of AdS and the classic Fermi-Pasta-Ulam-Tsingou problem.
The Classical Exchange Algebra of AdS5 x S5 String Theory
Marc Magro
2009-01-07T23:59:59.000Z
The classical exchange algebra satisfied by the monodromy matrix of AdS5 x S5 string theory in the Green-Schwarz formulation is determined by using a first-order Hamiltonian formulation and by adding to the Bena-Polchinski-Roiban Lax connection terms proportional to constraints. This enables in particular to show that the conserved charges of this theory are in involution. This result is obtained for a general world-sheet metric. The same exchange algebra is obtained within the pure spinor description of AdS5 x S5 string theory. These results are compared to the one obtained by A. Mikhailov and S. Schaefer-Nameki for the pure spinor formulation.
Clock synchronization for mobile ad hoc networks
Chandra, Rajan
2013-02-22T23:59:59.000Z
Time Protocol) used in wired networks (e.g. Internet) to Mobile Ad Hoc Networks (MANets). It may also be achieved by developing other algorithms that achieve clock synchronization and may be suitable for MANets. Using the Network Time Protocol (NTP...
Measuring value added characteristics in feeder cattle
Mathews, Crystal Dawn
2009-05-15T23:59:59.000Z
, cyclical effects, lot size, weight, breed type, sex, commingling, fed cattle futures price, and corn price were all found to have an impact on the sale price of feeder cattle. Feeder calves sold through MFA Health Track Beef Alliance and other value added...
Marius de Leeuw; Takuya Matsumoto; Sanefumi Moriyama; Vidas Regelskis; Alessandro Torrielli
2012-04-11T23:59:59.000Z
We discuss special quantum group (secret) symmetries of the integrable system associated to the AdS/CFT correspondence. These symmetries have by now been observed in a variety of forms, including the spectral problem, the boundary scattering problem, n-point amplitudes, the pure-spinor formulation and quantum affine deformations.
de Leeuw, Marius; Moriyama, Sanefumi; Regelskis, Vidas; Torrielli, Alessandro
2012-01-01T23:59:59.000Z
We discuss special quantum group (secret) symmetries of the integrable system associated to the AdS/CFT correspondence. These symmetries have by now been observed in a variety of forms, including the spectral problem, the boundary scattering problem, n-point amplitudes, the pure-spinor formulation and quantum affine deformations.
AD CONTENT CHECK LIST: o Company logo
Zakharov, Vladimir
AD CONTENT CHECK LIST: o Company logo o Address o Contact Info: Phone, web site, and/or e-mail o that will perfectly reflect your image! Acceptable Formats For Logos/Graphics/Photos High-Res (300 dpi) PDF, EPS
Universality of Long-Distance AdS Physics from the CFT Bootstrap
A. Liam Fitzpatrick; Jared Kaplan; Matthew T. Walters
2014-07-10T23:59:59.000Z
We begin by explicating a recent proof of the cluster decomposition principle in AdS_{d+1} from the CFT_d bootstrap in d > 2. The CFT argument also computes the leading interactions between distant objects in AdS, and we confirm the universal agreement between the CFT bootstrap and AdS gravity in the semi-classical limit. We proceed to study the generalization to 2d CFTs, which requires knowledge of the Virasoro conformal blocks in a lightcone OPE limit. We compute these blocks in a semiclassical, large central charge approximation, and use them to prove a suitably modified theorem. In particular, from the 2d bootstrap we prove the existence of large spin operators with fixed 'anomalous dimensions' indicative of the presence of deficit angles in AdS_3. As we approach the threshold for the BTZ black hole, interpreted as a CFT scaling dimension, the twist spectrum of large spin operators becomes dense. Due to the exchange of the Virasoro identity block, primary states above the BTZ threshold mimic a thermal background for light operators. We derive the BTZ quasi-normal modes, and we use the bootstrap equation to prove that the twist spectrum is dense. Corrections to thermality could be obtained from a more refined computation of the Virasoro conformal blocks.
Training Needs in Louisiana's Value-Added Forest Products Industry
Training Needs in Louisiana's Value-Added Forest Products Industry Richard VloskyRichard Vlosky-Added Training in Other States · The Need for Training in Louisiana-Past Research #12;Industry Development & Adding Value #12;Value-Added Industry Development is Multi-Faceted Marketing Workforce Training Strategic
The free energy of N=2 supersymmetric AdS_4 solutions of M-theory
Maxime Gabella; Dario Martelli; Achilleas Passias; James Sparks
2011-07-29T23:59:59.000Z
We show that general N=2 supersymmetric AdS_4 solutions of M-theory with non-zero M2-brane charge admit a canonical contact structure. The free energy of the dual superconformal field theory on S^3 and the scaling dimensions of operators dual to supersymmetric wrapped M5-branes are expressed via AdS/CFT in terms of contact volumes. In particular, this leads to topological and localization formulae for the coefficient of N^{3/2} in the free energy of such solutions.
Covariant propagator in AdS5 x S5 superspace
Peng Dai; Ru-Nan Huang; Warren Siegel
2010-02-10T23:59:59.000Z
We give an explicit superspace propagator for the chiral scalar field strength of 10D IIB supergravity on an AdS5 x S5 background. Because this space is conformally flat, the propagator is very simple, almost identical to that of flat space. We also give an explicit expansion over the Kaluza-Klein modes of S5. The fact that the full propagator is so much simpler suggests that, as in 2D conformal field theory, AdS/CFT calculations would be simpler without a mode expansion.
Renormalization, averaging, conservation laws and AdS (in)stability
Ben Craps; Oleg Evnin; Joris Vanhoof
2015-01-19T23:59:59.000Z
We continue our analytic investigations of non-linear spherically symmetric perturbations around the anti-de Sitter background in gravity-scalar field systems, and focus on conservation laws restricting the (perturbatively) slow drift of energy between the different normal modes due to non-linearities. We discover two conservation laws in addition to the energy conservation previously discussed in relation to AdS instability. A similar set of three conservation laws was previously noted for a self-interacting scalar field in a non-dynamical AdS background, and we highlight the similarities of this system to the fully dynamical case of gravitational instability. The nature of these conservation laws is best understood through an appeal to averaging methods which allow one to derive an effective Lagrangian or Hamiltonian description of the slow energy transfer between the normal modes. The conservation laws in question then follow from explicit symmetries of this averaged effective theory.
Extremal Static AdS Black Hole/CFT Correspondence in Gauged Supergravities
H. Lu; Jianwei Mei; C. N. Pope; J. Vazquez-Poritz
2009-01-13T23:59:59.000Z
A recently proposed holographic duality allows the Bekenstein-Hawking entropy of extremal rotating black holes to be calculated microscopically, by applying the Cardy formula to the two-dimensional chiral CFTs associated with certain reparameterisations of azimuthal angular coordinates in the solutions. The central charges are proportional to the angular momenta of the black hole, and so the method degenerates in the case of static (non-rotating) black holes. We show that the method can be extended to encompass such charged static extremal AdS black holes by using consistent Kaluza-Klein sphere reduction ansatze to lift them to exact solutions in the low-energy limits of string theory or M-theory, where the electric charges become reinterpreted as angular momenta associated with internal rotations in the reduction sphere. We illustrate the procedure for the examples of extremal charged static AdS black holes in four, five, six and seven dimensions.
Weak Field Collapse in AdS: Introducing a Charge Density
Elena Caceres; Arnab Kundu; Juan F. Pedraza; Di-Lun Yang
2015-06-29T23:59:59.000Z
We study the effect of a non-vanishing chemical potential on the thermalization time of a strongly coupled large $N_c$ gauge theory in $(2+1)$-dimensions, using a specific bottom-up gravity model in asymptotically AdS space. We first construct a perturbative solution to the gravity-equations, which dynamically interpolates between two AdS black hole backgrounds with different temperatures and chemical potentials, in a perturbative expansion of a bulk neutral scalar field. In the dual field theory, this corresponds to a quench dynamics by a marginal operator, where the corresponding coupling serves as the small parameter in which the perturbation is carried out. The evolution of non-local observables, such as the entanglement entropy, suggests that thermalization time decreases with increasing chemical potential. We also comment on the validity of our perturbative analysis.
New ${\\cal N} = 1$ supersymmetric $AdS_5$ backgrounds in Type IIA supergravity
Konstadinos Sfetsos; Daniel C. Thompson
2014-08-27T23:59:59.000Z
We present a family of N=1 supersymmetric backgrounds in type-IIA supergravity and their lifts to eleven-dimensional supergravity. These are of the form $AdS_5 \\times X^5$ and are characterised by an $SU(2)$ structure. The internal space, $X^5$, is obtained from the known Sasaki-Einstein manifolds, $Y^{p,q}$, via an application of non-Abelian T-duality.
Perturbative calculation of quasinormal modes of AdS Schwarzschild black holes
Musiri, Suphot; Ness, Scott; Siopsis, George [Department of Physics, Srinakharinwirot University, Bangkok 10110 (Thailand); Department of Physics and Astronomy, The University of Tennessee, Knoxville, Tennessee 37996-1200 (United States)
2006-03-15T23:59:59.000Z
We calculate analytically quasinormal modes of AdS Schwarzschild black holes including first-order corrections. We consider massive scalar, gravitational and electromagnetic perturbations. Our results are in good agreement with numerical calculations. In the case of electromagnetic perturbations, ours is the first calculation to provide an analytic expression for quasinormal frequencies, because the effective potential vanishes at zeroth order. We show that the first-order correction is logarithmic.
A new holographic limit of AdS5 x S5
Machiko Hatsuda; Warren Siegel
2003-02-06T23:59:59.000Z
We re-examine the projective lightcone limit of the gauge-invariant Green-Schwarz action on 5D anti-de Sitter x the five-sphere. It implies the usual holography for AdS5, but also (a complex) one for S5. The result is N=4 projective superspace, which unlike N=4 harmonic superspace can describe N=4 super Yang-Mills off shell.
Texas Wildlife Services
2007-03-13T23:59:59.000Z
there are ?flu-like? symptoms such as fatigue, fever, sore throat, nausea and cough- ing. According to the Texas Department of Health, many of those infected develop a small red lesion around the site of the tick or flea bite. As the disease progresses many...
John H. Schwarz
2009-07-28T23:59:59.000Z
The study of AdS/CFT (or gauge/gravity) duality has been one of the most active and illuminating areas of research in string theory over the past decade. The scope of its relevance and the insights it is providing seem to be ever expanding. In this talk I briefly describe some of the attempts to explore how the duality works for maximally supersymmetric systems.
ARM KAZR-ARSCL Value Added Product
DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]
Jensen, Michael
The Ka-band ARM Zenith Radars (KAZRs) have replaced the long-serving Millimeter Cloud Radars, or MMCRs. Accordingly, the primary MMCR Value Added Product (VAP), the Active Remote Sensing of CLouds (ARSCL) product, is being replaced by a KAZR-based version, the KAZR-ARSCL VAP. KAZR-ARSCL provides cloud boundaries and best-estimate time-height fields of radar moments.
ARM KAZR-ARSCL Value Added Product
Jensen, Michael
2012-09-28T23:59:59.000Z
The Ka-band ARM Zenith Radars (KAZRs) have replaced the long-serving Millimeter Cloud Radars, or MMCRs. Accordingly, the primary MMCR Value Added Product (VAP), the Active Remote Sensing of CLouds (ARSCL) product, is being replaced by a KAZR-based version, the KAZR-ARSCL VAP. KAZR-ARSCL provides cloud boundaries and best-estimate time-height fields of radar moments.
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AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:5 TablesExports(Journal Article)41clothThe Bonneville Power AdministrationHawaiiEnergy StorageDepartmentPOPSECFemtosecondAds Subscribe | Contact Fermilab
Adding coal dust to coal batch
V.S. Shved; A.V.Berezin [OAO Koks, Kemerovo (Russian Federation)
2009-05-15T23:59:59.000Z
The granulometric composition of coke dust from the dry-slaking machine is determined. The influence of additions of 3-7% coke dust on the quality of industrial coking batch and the coke obtained by box coking is estimated. Adding 1% coke dust to coking batch does not markedly change the coke quality. Industrial equipment for the supply of dry-slaking dust to the batch is described.
ADS: The Next Generation Search Platform
Accomazzi, Alberto; Henneken, Edwin A; Chyla, Roman; Luker, James; Grant, Carolyn S; Thompson, Donna M; Holachek, Alexandra; Dave, Rahul; Murray, Stephen S
2015-01-01T23:59:59.000Z
Four years after the last LISA meeting, the NASA Astrophysics Data System (ADS) finds itself in the middle of major changes to the infrastructure and contents of its database. In this paper we highlight a number of features of great importance to librarians and discuss the additional functionality that we are currently developing. Starting in 2011, the ADS started to systematically collect, parse and index full-text documents for all the major publications in Physics and Astronomy as well as many smaller Astronomy journals and arXiv e-prints, for a total of over 3.5 million papers. Our citation coverage has doubled since 2010 and now consists of over 70 million citations. We are normalizing the affiliation information in our records and, in collaboration with the CfA library and NASA, we have started collecting and linking funding sources with papers in our system. At the same time, we are undergoing major technology changes in the ADS platform which affect all aspects of the system and its operations. We hav...
Variations of 14-C around AD 775 and AD 1795 - due to solar activity
Neuhaeuser, Ralph
2015-01-01T23:59:59.000Z
The motivation for our study is the disputed cause for the strong variation of 14-C around AD 775. Our method is to compare the 14-C variation around AD 775 with other periods of strong variability. Our results are: (a) We see three periods, where 14-C varied over 200 yr in a special way showing a certain pattern of strong secular variation: after a Grand Minimum with strongly increasing 14-C, there is a series of strong short-term drop(s), rise(s), and again drop(s) within 60 yr, ending up to 200 yr after the start of the Grand Minimum. These three periods include the strong rises around BC 671, AD 775, and AD 1795. (b) We show with several solar activity proxies (radioisotopes, sunspots, and aurorae) for the AD 770s and 1790s that such intense rapid 14-C increases can be explained by strong rapid decreases in solar activity and, hence, wind, so that the decrease in solar modulation potential leads to an increase in radioisotope production. (c) The strong rises around AD 775 and 1795 are due to three effects...
Entropy of near-extremal black holes in AdS5
Simon, Joan; Balasubramanian, Vijay; de Boer, Jan; Jejjala, Vishnu; Simon, Joan
2007-07-24T23:59:59.000Z
We construct the microstates of near-extremal black holes in AdS_5 x S5 as gases of defects distributed in heavy BPS operators in the dual SU(N) Yang-Mills theory. These defects describe open strings on spherical D3-branes in the S5, and we show that they dominate the entropy by directly enumerating them and comparing the results with a partition sum calculation. We display new decoupling limits in which the field theory of the lightest open strings on the D-branes becomes dual to a near-horizon region of the black hole geometry. In the single-charge black hole we find evidence for an infrared duality between SU(N) Yang-Mills theories that exchanges the rank of the gauge group with an R-charge. In the two-charge case (where pairs of branes intersect on a line), the decoupled geometry includes an AdS_3 factor with a two-dimensional CFT dual. The degeneracy in this CFT accounts for the black hole entropy. In the three-charge case (where triples of branes intersect at a point), the decoupled geometry contains an AdS_2 factor. Below a certain critical mass, the two-charge system displays solutions with naked timelike singularities even though they do not violate a BPS bound. We suggest a string theoretic resolution of these singularities.
2013-01-01T23:59:59.000Z
Celular, Genetica y Fisiologia, Facultad de Ciencias,Celular, Genetica y Fisiologia, Facultad de Ciencias,
Li, Qian
2014-11-28T23:59:59.000Z
GPR50, an X-linked orphan G protein-coupled receptor (GPCR), is a risk factor for bipolar disorder (BD) in female subjects. It has been shown that GPR50 plays a part in neurite outgrowth, glucocorticoid receptor signalling ...
2013-01-01T23:59:59.000Z
Departamento de Biologia Celular, Genetica y Fisiologia,Departamento de Biologia Celular, Genetica y Fisiologia,
Coltman, Robin Bruce
2012-06-22T23:59:59.000Z
The integrity of brain white matter is vital for the interneuronal signalling between distinct brain regions required for normal cognitive function. White matter integrity is compromised with ageing and could contribute ...
Visualization and Functional Analysis of Genome-Wide Association Results
Li, Jing
genetic risks of several complex diseases including cancers, obesity, and type 2 diabetes using GWAS such as neurodegenerative diseases (e.g., Alzheimer's disease (AD) and Parkinson's disease), cardiovascular diseases patterns of genetic markers and the trait of interest within families, and establish linkage of disease
Not Available
1991-12-20T23:59:59.000Z
After two workers at the nuclear weapons plant at Oak Ridge National Laboratory in Tennessee were diagnosed earlier this year with chronic beryllium disease (CBD), a rare and sometimes fatal scarring of the lungs, the Department of Energy ordered up a 4-year probe. Now, part of that probe has begun - tests conducted by the Oak Ridge Associated Universities' Center for Epidemiological Research measuring beryllium sensitivity in 3,000 people who've been exposed to the metal's dust since Manhattan Project managers opened the Y-12 plant at Oak Ridge in 1943. Currently, 119 Y-12 employees process beryllium, which has a number of industrial uses, including rocket heat shields and nuclear weapon and electrical components. The disease often takes 20 to 25 years to develop, and the stricken employees haven't worked with beryllium for years. There is no cure for CBD, estimated to strike 2% of people exposed to the metal. Anti-inflammatory steroids alleviate such symptoms as a dry cough, weight loss, and fatigue. Like other lung-fibrosis diseases that are linked to lung cancer, some people suspect CBD might cause some lung cancer. While difficult to diagnose, about 900 cases of CBD have been reported since a Beryllium Case Registry was established in 1952. The Department of Energy (DOE) estimates that about 10,000 DOE employees and 800,000 people in private industry have worked with beryllium.
Secret Symmetries of Type IIB Superstring Theory on AdS3 x S3 x M4
Antonio Pittelli; Alessandro Torrielli; Martin Wolf
2014-11-06T23:59:59.000Z
We establish features of so-called Yangian secret symmetries for AdS3 type IIB superstring backgrounds thus verifying the persistence of such symmetries to this new instance of the AdS/CFT correspondence. Specifically, we find two a priori different classes of secret symmetry generators. One class of generators, anticipated from the previous literature, is more naturally embedded in the algebra governing the integrable scattering problem. The other class of generators is more elusive, and somewhat closer in its form to its higher-dimensional AdS5 counterpart. All of these symmetries respect left-right crossing. In addition, by considering the interplay between left and right representations, we gain a new perspective on the AdS5 case. We also study the RTT-realisation of the Yangian in AdS3 backgrounds thus establishing a new incarnation of the Beisert-de Leeuw construction.
Alternative approach to the regularization of odd dimensional AdS gravity
Pablo Mora
2007-08-23T23:59:59.000Z
In this paper I present an action principle for odd dimensional AdS gravity which consists of introducing another manifold with the same boundary and a very specific boundary term. This new action allows and alternative approach to the regularization of the theory, yielding a finite euclidean action and finite conserved charges. The choice of the boundary term is justified on the grounds that an enhanced 'almost off-shell' local AdS/Conformal symmetry arises for that very special choice. One may say that the boundary term is dictated by a guiding symmetry principle. Two sets of boundary conditions are considered, which yield regularization procedures analogous to (but different from) the standard 'background substraction' and 'counterterms' regularization methods. The Noether charges are constructed in general. As an application it is shown that for Schwarszchild-AdS black holes the charge associated to the time-like Killing vector is finite and is indeed the mass. The Euclidean action for Schwarzschild-AdS black holes is computed, and it turns out to be finite, and to yield the right thermodynamics. The previous paragraph may be interpreted in the sense that the boundary term dictated by the symmetry principle is the one that correctly regularizes the action.
Ad Lucem: Modeling Market Transformation Pathways Workshop
Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankShale_Gas.pdfService on the TargetFY12 DOE -NAT IONA L S47.1 (June 2004) 1June|AD LUCEM ... TOWARD THE
Holographic formula for the determinant of the scattering operator in thermal AdS
Danilo E. Díaz
2009-08-26T23:59:59.000Z
A 'holographic formula' expressing the functional determinant of the scattering operator in an asymptotically locally anti-de Sitter(ALAdS) space has been proposed in terms of a relative functional determinant of the scalar Laplacian in the bulk. It stems from considerations in AdS/CFT correspondence of a quantum correction to the partition function in the bulk and the corresponding subleading correction at large N on the boundary. In this paper we probe this prediction for a class of quotients of hyperbolic space by a discrete subgroup of isometries. We restrict to the simplest situation of an abelian group where the quotient geometry describes thermal AdS and also the non-spinning BTZ instanton. The bulk computation is explicitly done using the method of images and the answer can be encoded in a (Patterson-)Selberg zeta-function.
On Thermodynamics of AdS Black Holes in Arbitrary Dimensions
A. Belhaj; M. Chabab; H. El Moumni; M. B. Sedra
2012-09-23T23:59:59.000Z
Considering the cosmological constant $\\Lambda$ as a thermodynamic pressure and its conjugate quantity as a thermodynamic volume as proposed in Kubiznak and Mann (2012), we discuss the critical behavior of charged AdS black hole in arbitrary dimensions $d$. In particular, we present a comparative study in terms of the spacetime dimension $d$ and the displacement of critical points controlling the transition between the small and the large black holes. Such behaviors vary nicely in terms of $d$. Among our result in this context consists in showing that the equation of state for a charged RN-AdS black hole predicts an universal number given by $\\frac{2d-5}{4d-8}$. The three dimensional solution is also discussed.
Goldberg, Corey; Carey, Kathleen E
2013-01-01T23:59:59.000Z
thorascopic surgery. Bullous Lung Disease REFERENCES 1.S, Kaiser LR. Giant bullous lung disease: evaluation,for bullous disease of the lung. Eur J Cardiothorac Surg.
Dynamic address allocation protocols for Mobile ad hoc networks
Patchipulusu, Praveena
2001-01-01T23:59:59.000Z
Address allocation is an important issue in Mobile ad hoc networks. This thesis proposes solutions to assign unique IP addresses to nodes participating in Mobile ad hoc networks and evaluates the proposed solutions. Address allocation protocols...
Managing On-air Ad Inventory in Broadcast Television
Bollapragada, Srinivas; Mallik, Suman
2008-01-01T23:59:59.000Z
Motivated by the experiences of the National Broadcasting Company (NBC), we present an analytical model for managing on-air ad inventory in broadcast television. The ad inventory in this industry is priced based on rating ...
Superconductors for superstrings on AdS_5 x T^{1,1}
Francesco Aprile; Andrea Borghese; Aldo Dector; Diederik Roest; Jorge G. Russo
2012-05-09T23:59:59.000Z
We construct a one-parameter family of five-dimensional N=2 supergravity Lagrangians with an SU(2,1) / U(2) hypermultiplet. For certain values of the parameter, these are argued to describe the dynamics of scalar modes of superstrings on AdS_5 x T^{1,1}, and therefore to be dual to specific chiral primary operators of Klebanov-Witten superconformal field theory. We demonstrate that, below a critical temperature, the thermodynamics is dominated by charged black holes with hair for the scalars that are dual to the operator of lowest conformal dimension 3/2. The system thus enters into a superconducting phase where condenses.
Integrable $?$-deformations: Squashing Coset CFTs and $AdS_5\\times S^5$
Saskia Demulder; Konstantinos Sfetsos; Daniel C. Thompson
2015-04-10T23:59:59.000Z
We examine integrable $\\lambda$-deformations of $SO(n+1)/SO(n)$ coset CFTs and their analytic continuations. We provide an interpretation of the deformation as a squashing of the corresponding coset $\\sigma$-model's target space. We realise the $\\lambda$-deformation for $n=5$ case as a solution to supergravity supported by non-vanishing five-form and dilaton. This interpolates between the coset CFT $SO(4,2)/SO(4,1)\\times SO(6)/SO(5)$ constructed as a gauged WZW model and the non-Abelian T-dual of the $AdS_5\\times S^5$ spacetime.
Transition from AdS universe to DS universe in the BPP model
Wontae Kim; Myungseok Yoon
2007-03-03T23:59:59.000Z
It can be shown that in the BPP model the smooth phase transition from the asymptotically decelerated AdS universe to the asymptotically accelerated DS universe is possible by solving the modified semiclassical equations of motion. This transition comes from noncommutative Poisson algebra, which gives the constant curvature scalars asymptotically. The decelerated expansion of the early universe is due to the negative energy density with the negative pressure induced by quantum back reaction, and the accelerated late-time universe comes from the positive energy and the negative pressure which behave like dark energy source in recent cosmological models.
On Heat Properties of AdS Black Holes in Higher Dimensions
A. Belhaj; M. Chabab; H. EL Moumni; K. Masmar; M. B. Sedra; A. Segui
2015-07-01T23:59:59.000Z
We investigate the heat properties of AdS Black Holes in higher dimensions. We consider the study of the corresponding thermodynamical properties including the heat capacity explored in the determination of the black hole stability. In particular, we compute the heat latent. To overcome the instability problem, the Maxwell construction, in the (T,S)-plane, is elaborated. This method is used to modify the the Hawking-Page phase structure by removing the negative heat capacity regions. Then, we discuss the thermodynamic cycle and the heat engines using the way based on the extraction of the work from a black hole solution.
Aspects of Axion Phenomenology in a slice of AdS_5
Thomas Flacke; David Maybury
2006-12-11T23:59:59.000Z
Motivated by multi-throat considerations, we study the phenomenological implications of a bulk axion in a slice of AdS_5 with a large extra dimension: k~0.01 eV, kR > 1. In particular, we compare axion physics with a warped geometry to axions in flat compactifications. As in flat compactification scenarios, we find that the mass of the axion can become independent from the underlying Peccei-Quinn scale. Surprisingly, we find that in warped extra dimensions the axion's invisibility, cosmological viability, and basic phenomenology remain essentially unaltered in comparison to axions in flat compactifications.
AdS/QCD at finite density and temperature
Kim, Y., E-mail: ykim@apctp.org [Pohang University of Science and Technology, Asia Pacific Center for Theoretical Physics and Department of Physics (Korea, Republic of)
2012-07-15T23:59:59.000Z
We review some basics of AdS/QCD following a non-standard path and list a few results from AdS/QCD or holographic QCD. The non-standard path here is to use the analogy of the way one obtains an effective model of QCD like linear sigma model and the procedure to construct an AdS/QCD model based on the AdS/CFT dictionary.
AUAARHUS UNIVERSITY Adding a bonus card AU Finance and Planning
AUAARHUS UNIVERSITY Adding a bonus card AU Finance and Planning Financial Management 12/02/2013 Page 1 of 6 Guide to adding a bonus card in CWT's online system Log on to CWT: https://sso.carlsonwagonlit.com/login.do Type in your username and password Click on "Sign on" #12;AUAARHUS UNIVERSITY Adding a bonus card AU
LEARNING-BASED ROUTE MANAGEMENT IN WIRELESS AD HOC NETWORKS
Littman, Michael L.
and Wade Trappe The nodes in a wireless ad hoc network must act as routers in a self-configuring network to shortest-path routing protocols for managing router congestion and noise in wireless ad hoc networks. iiLEARNING-BASED ROUTE MANAGEMENT IN WIRELESS AD HOC NETWORKS BY BRIAN RUSSELL A dissertation
Low-Interference Topology Control for Wireless Ad Hoc Networks
Li, Xiang-Yang
wireless ad hoc networks. Many aspects of the networking will affect the energy consumption of the wireless may cause larger energy consumption. In wireless ad hoc networks, each wireless device can selectively1 Low-Interference Topology Control for Wireless Ad Hoc Networks Kousha Moaveni-Nejad, Xiang
Approximate Minimum-Energy Multicasting in Wireless Ad Hoc Networks
Liang, Weifa
Approximate Minimum-Energy Multicasting in Wireless Ad Hoc Networks Weifa Liang, Senior Member, IEEE Abstract--A wireless ad hoc network consists of mobile nodes that are equipped with energy on energy conservation in wireless ad hoc networks have been conducted. For example, energy efficient
C-AD electron-cooling Photocathode and Laser
C-AD electron-cooling Photocathode and Laser A. Burrill and T. Rao #12;C-AD electron system Design of 2nd and third generation system · Laser system Requirements Commercial Capsule fabrication · Brazing · Metallization #12;C-AD electron-cooling Overview Photocathode Requirements
Review of AdS/CFT Integrability, Chapter IV.3: N=6 Chern-Simons and Strings on AdS4xCP3
Thomas Klose
2012-03-27T23:59:59.000Z
We review the duality and integrability of N=6 superconformal Chern-Simons theory in three dimensions and IIA superstring theory on the background AdS4xCP3. We introduce both of these models and describe how their degrees of freedom are mapped to excitations of a long-range integrable spin-chain. Finally, we discuss the properties of the Bethe equations, the S-matrix and the algebraic curve that are special to this correspondence and differ from the case of N=4 SYM theory and strings on AdS5xS5.
Emergent IR dual 2d CFTs in charged AdS5 black holes
Jan de Boer; Maria Johnstone; M. M. Sheikh-Jabbari; Joan Simon
2011-12-20T23:59:59.000Z
We study the possible dynamical emergence of IR conformal invariance describing the low energy excitations of near-extremal R-charged global AdS5 black holes. We find interesting behavior especially when we tune parameters in such a way that the relevant extremal black holes have classically vanishing horizon area, i.e. no classical ground-state entropy, and when we combine the low energy limit with a large N limit of the dual gauge theory. We consider both near-BPS and non-BPS regimes and their near horizon limits, emphasize the differences between the local AdS3 throats emerging in either case, and discuss potential dual IR 2d CFTs for each case. We compare our results with the predictions obtained from the Kerr/CFT correspondence, and obtain a natural quantization for the central charge of the near-BPS emergent IR CFT which we interpret in terms of the open strings stretched between giant gravitons.
Shear Viscosity from AdS Born-Infeld Black Holes
Rong-Gen Cai; Ya-Wen Sun
2008-09-23T23:59:59.000Z
We calculate the shear viscosity in the frame of AdS/CFT correspondence for the field theory with a gravity dual of Einstein-Born-Infeld gravity. We find that the ratio of $\\eta/s$ is still the conjectured universal value $1/4\\pi$ at least up to the first order of the Born-Infeld parameter $1/b^2$.
Quartic AdS Interactions in Higher-Spin Gravity from Conformal Field Theory
Bekaert, Xavier; Ponomarev, Dmitry; Sleight, Charlotte
2015-01-01T23:59:59.000Z
Clarifying the locality properties of higher-spin gravity is a pressing task, but notoriously difficult due to the absence of a weakly-coupled flat regime. The simplest non-trivial case where this question can be addressed is the quartic self-interaction of the AdS scalar field present in the higher-spin multiplet. We investigate this issue in the context of the holographic duality between the minimal bosonic higher-spin theory on AdS$_4$ and the free $O\\left(N\\right)$ vector model in three dimensions. In particular, we determine the exact explicit form of the derivative expansion of the bulk scalar quartic vertex. The quartic vertex is obtained from the field theory four-point function of the operator dual to the bulk scalar, by making use of our previous results for the Witten diagrams of higher-spin exchanges. This is facilitated by establishing the conformal block expansions of both the boundary four-point function and the dual bulk Witten diagram amplitudes. We show that the vertex we find satisfies a ge...
Geometric free energy of toric AdS4/CFT3 models
Sangmin Lee; Daisuke Yokoyama
2015-01-22T23:59:59.000Z
We study the supersymmetric free energy of three dimensional Chern-Simons-matter theories holographically dual to AdS$_4$ times toric Sasaki-Einstein seven-manifolds. In the large $N$ limit, we argue that the square of the free energy can be written as a quartic polynomial of trial R-charges. The coefficients of the polynomial are determined geometrically from the toric diagrams. We present the coefficients of the quartic polynomial explicitly for generic toric diagrams with up to 6 vertices, and some particular diagrams with 8 vertices. Decomposing the trial R-charges into mesonic and baryonic variables, and eliminating the baryonic ones, we show that the quartic polynomial reproduces the inverse of the Martelli-Sparks-Yau volume function. On the gravity side, we explore the possibility of using the same quartic polynomial as the prepotential in the AdS gauged supergravity. Comparing Kaluza-Klein gravity and gauged supergravity descriptions, we find perfect agreement in the mesonic sector but some discrepancy in the baryonic sector.
Vacuum densities for a thick brane in AdS spacetime
A. A. Saharian; A. L. Mkhitaryan
2007-10-18T23:59:59.000Z
For a massive scalar field with general curvature coupling parameter we evaluate Wightman function, vacuum expectation values of the field square and the energy-momentum tensor induced by a $Z_{2}$-symmetric brane with finite thickness located on $(D+1)$-dimensional AdS bulk. For the general case of static plane symmetric interior structure the expectation values in the region outside the brane are presented as the sum of free AdS and brane induced parts. For a conformally coupled massless scalar the brane induced part in the vacuum energy-momentum tensor vanishes. In the limit of strong gravitational fields the brane induced parts are exponentially suppressed for points not too close to the brane boundary. As an application of general results a special model is considered in which the geometry inside the brane is a slice of the Minkowski spacetime orbifolded along the direction perpendicular to the brane. For this model the Wightman function, vacuum expectation values of the field square and the energy-momentum tensor inside the brane are evaluated. It is shown that for both minimally and conformally coupled scalar fields the interior vacuum forces acting on the brane boundaries tend to decrease the brane thickness.
Dual Superconformal Symmetry from AdS5 x S5 Superstring Integrability
Niklas Beisert; Riccardo Ricci; Arkady Tseytlin; Martin Wolf
2008-11-17T23:59:59.000Z
We discuss 2d duality transformations in the classical AdS5 x S5 superstring and their effect on the integrable structure. T-duality along four directions in Poincare parametrization of AdS5 maps the bosonic part of the superstring action into itself. On bosonic level, this duality may be understood as a symmetry of the first-order (phase space) system of equations for the coset components of the current. The associated Lax connection is invariant modulo the action of an so(2,4)-automorphism. We then show that this symmetry extends to the full superstring, provided one supplements the transformation of the bosonic components of the current with a transformation on the fermionic ones. At the level of the action, this symmetry can be seen by combining the bosonic duality transformation with a similar one applied to part of the fermionic superstring coordinates. As a result, the full superstring action is mapped into itself, albeit in a different kappa-symmetry gauge. One implication is that the dual model has the same superconformal symmetry group as the original one, and this may be seen as a consequence of the integrability of the superstring. The invariance of the Lax connection under the duality implies a map on the full set of conserved charges that should interchange some of the Noether (local) charges with hidden (non-local) ones and vice versa.
Sen, Sevil
ITA CONFERENCE 1569048773 THREAT MODELLING FOR MOBILE AD HOC AND SENSOR NETWORKS 1 Threat Modelling. Chivers, Olwen Worthington and Pankaj Rohatgi Abstract-- This paper introduces a threat model for ad hoc and mobile ad hoc networks (MANETS). It identifies threat categories, modes of use, and a variety of threats
2013 S. Karger AG, Basel 16645464/13/00310417$38.00/0
Paris-Sud XI, Université de
Médecine Interne Gériatrique, Pôle de Personnes Âgées et Soins à Domicile, Centre Hospitalier Universitaire which Alzheimer's disease (AD) is managed. In this study, we ex- plore three approaches that can help
Aerosol Best Estimate Value-Added Product
Flynn, C; Turner, D; Koontz, A; Chand, D; Sivaraman, C
2012-07-19T23:59:59.000Z
The objective of the Aerosol Best Estimate (AEROSOLBE) value-added product (VAP) is to provide vertical profiles of aerosol extinction, single scatter albedo, asymmetry parameter, and Angstroem exponents for the atmospheric column above the Central Facility at the ARM Southern Great Plains (SGP) site. We expect that AEROSOLBE will provide nearly continuous estimates of aerosol optical properties under a range of conditions (clear, broken clouds, overcast clouds, etc.). The primary requirement of this VAP was to provide an aerosol data set as continuous as possible in both time and height for the Broadband Heating Rate Profile (BBHRP) VAP in order to provide a structure for the comprehensive assessment of our ability to model atmospheric radiative transfer for all conditions. Even though BBHRP has been completed, AEROSOLBE results are very valuable for environmental, atmospheric, and climate research.
ALZHEIMER'S AMYLOID-BETA PEPTIDE INHIBITS SODIUM/CALCIUM EXCHANGE MEASURED IN RAT AND
ALZHEIMER'S AMYLOID-BETA PEPTIDE INHIBITS SODIUM/CALCIUM EXCHANGE MEASURED IN RAT AND HUMAN BRAIN-beta140 (A 140) and A 2535 reduced vesicular Ca2+ content. Both peptides produced a maximal reduction in Ca2+ content of approximately 50%. The peptides reduced Ca2+ content with similar potency and half
Simultaneous Segmentation and Grading of Hippocampus for Patient Classification with Alzheimer's
Paris-Sud XI, Université de
Simultaneous Segmentation and Grading of Hippocampus for Patient Classification with Alzheimer library used during our experiments was composed by 2 populations, 50 Cognitively Normal subjects (CN of the HC at the same time resulted in an efficient patient classification with a success rate of 90
Vascular health, diabetes, APOE and dementia: The Aging, Demographics, And Memory Study
Llewellyn, David J; Lang, Iain A; Matthews, Fiona E; Plassman, Brenda L; Rogers, Mary A M; Morgenstern, Lewis B; Fisher, Gwenith G; Kabeto, Mohammed U; Langa, Kenneth M
2010-06-24T23:59:59.000Z
with dementia. Introduction Identification of modifiable risk factors for Alzheimer’s disease (AD), vascular dementia (VaD), and other demen- tias could potentially lead to a reduction in the human and economic costs these conditions place on aging populations... , hypertension, diabetes, heart disease, and stroke – have been studied to determine their relation to AD and VaD. However, many of these prior studies have been based on highly selected clinical samples or community-based samples from geo- graphically localized...
Conformal Transformations and Strings for an Accelerating Quark-Antiquark Pair in AdS3
Shijong Ryang
2014-12-08T23:59:59.000Z
From a simple moving open string solution dual to a moving heavy quark with constant velocity in the Poincare AdS_3 spacetime, we construct an accerlerating open string solution dual to a heavy quark-antiquark pair accelerated in opposite directions by performing the three mappings such as the SL(2,R)_L x SL(2,R)_R isometry transformation, the special conformal transformation and the conformal SO(2,2) transformation. Using the string sigma model action we construct two open string solutions staying in two different regions whose dividing line is associated with the event horizon appeared on the string worldsheet and obtain the accelerating open string solution by gluing two such solutions.
Emerging Non-Anomalous Baryonic Symmetries in the AdS_5/CFT_4 Correspondence
Nessi Benishti
2011-06-06T23:59:59.000Z
We study the breaking of baryonic symmetries in the AdS_5/CFT_4 correspondence for D3 branes at Calabi-Yau three-fold singularities. This leads, for particular VEVs, to the emergence of non-anomalous baryonic symmetries during the renormalization group flow. We claim that these VEVs correspond to critical values of the B-field moduli in the dual supergravity backgrounds. We study in detail the C^3/Z_3 orbifold, the cone over F_0 and the C^3/Z_5 orbifold. For the first two examples, we study the dual supergravity backgrounds that correspond to the breaking of the emerging baryonic symmetries and identify the expected Goldstone bosons and global strings in the infra-red. In doing so we confirm the claim that the emerging symmetries are indeed non-anomalous baryonic symmetries.
Emergent Space and the Example of AdS_5XS^5
Frank Ferrari
2013-05-06T23:59:59.000Z
We explain how to build field theoretic observables from which the geometrical properties of a dual holographic formulation can be read off straightforwardly. In some cases this construction yields explicit and calculable models of emergent space. We illustrate the idea on the type IIB background generated by N D3-branes in the near horizon limit, for which a full derivation from first principles can be presented. The six transverse dimensions emerge at large N and we find the full AdS_5XS^5 metric and self-dual Ramond-Ramond field strength on the resulting ten dimensional space-time, with the correct radii and quantization law. We briefly discuss possible applications and generalizations.
The holographic superconductors in higher-dimensional AdS soliton
Chong Oh Lee
2012-07-30T23:59:59.000Z
We explore the behaviors of the holographic superconductors at zero temperature for a charged scalar field coupled to a Maxwell field in higher-dimensional AdS soliton spacetime via analytical way. In the probe limit, we obtain the critical chemical potentials increase linearly as a total dimension $d$ grows up. We find that the critical exponent for condensation operator is obtained as 1/2 independently of $d$, and the charge density is linearly related to the chemical potential near the critical point. Furthermore, we consider a slightly generalized setup the Einstein-Power-Maxwell field theory, and find that the critical exponent for condensation operator is given as $1/(4-2n)$ in terms of a power parameter $n$ of the Power-Maxwell field, and the charge density is proportional to the chemical potential to the power of $1/(2-n)$.
The S-matrix of the AdS5 x S5 superstring
Marius de Leeuw
2010-07-28T23:59:59.000Z
In this article we review the world-sheet scattering theory of strings on AdS 5 x S5. The asymptotic spectrum of this world-sheet theory contains both fundamental particles and bound states of the latter. We explicitly derive the S-matrix that describes scattering of arbitrary bound states. The key feature that enables this derivation is the so-called Yangian symmetry which is related to the centrally extended su(2|2) superalgebra. Subsequently, we study the universal algebraic properties of the found S-matrix. As in many integrable models, the S-matrix plays a key role in the determination of the energy spectrum. In this context, we employ the Bethe ansatz approach to compute the large volume energy spectrum of string bound states.
The Bound State S-Matrix for AdS5 x S5 Superstring
Gleb Arutyunov; Marius de Leeuw; Alessandro Torrielli
2011-08-24T23:59:59.000Z
We determine the S-matrix that describes scattering of arbitrary bound states in the light-cone string theory in AdS5 x S5. The corresponding construction relies on the Yangian symmetry and the superspace formalism for the bound state representations. The basic analytic structure supporting the S-matrix entries turns out to be the hypergeometric function 4F3. We show that for particular bound state numbers it reproduces all the scattering matrices previously obtained in the literature. Our findings should be relevant for the TBA and Luescher approaches to the finite-size spectral problem. They also shed some light on the construction of the universal R-matrix for the centrally-extended psu(2|2) superalgebra.
Semiclassical Strings in Electric and Magnetic Fields Deformed $AdS_5 \\times S^5$ Spacetimes
Wung-Hong Huang
2006-01-06T23:59:59.000Z
We first apply the transformation of mixing azimuthal and internal coordinate or mixing time and internal coordinate to the 11D M-theory with a stack N M2-branes to find the spacetime of a stack of N D2-branes with magnetic or electric flux in 10 D IIA string theory, after the Kaluza-Klein reduction. We then perform the T duality to the spacetime to find the background of a stack of N D3-branes with magnetic or electric flux. In the near-horizon limit the background becomes the magnetic or electric field deformed $AdS_5 \\times S^5$. We adopt an ansatz to find the classical string solution which is rotating in the deformed $S^5$ with three angular momenta in the three rotation planes. The relations between the classical string energy and its angular momenta are found and results show that the external magnetic and electric fluxes will increase the string energy. Therefore, from the AdS/CFT point of view, the corrections of the anomalous dimensions of operators in the dual SYM theory will be positive. We also investigate the small fluctuations in these solutions and discuss the effects of magnetic and electric fields on the stability of these classical rotating string solutions. Finally, we find the possible solutions of string pulsating on the deformed spacetimes and show that the corrections to the anomalous dimensions of operators in the dual SYM theory are non-negative.
Morimoto, Richard
, such as Alzhei- mer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS, we describe genetic exper- iments in yeast that identified a potential disease-modifying pathwaySymposium Disease-Modifying Pathways in Neurodegeneration Steven Finkbeiner,1,2,3 Ana Maria Cuervo
Benedek, George B.
Oligomeric forms of amyloid ?-protein (A?) are key neurotoxins in Alzheimer’s disease (AD). Previously, we found that C-terminal fragments (CTFs) of A?42 interfered with assembly of full-length A?42 and inhibited A?42-induced ...
Money Market Mutual Funds: An Experiement in Ad Hoc Deregulation
Rosen, Kenneth T.; Katz, Lawrence
1981-01-01T23:59:59.000Z
of the market. A full deregulation of the deposit marketsity range. Full deregulation of financial institutions will,periment in ad hoc deregulation. -29- APPENDIX 1 . §Money
Maximizing the throughput of large ad hoc wireless networks
Hua, Yingbo; Huang, Yi; J, Garcia-Luna-Aceves J
2006-01-01T23:59:59.000Z
The transport capacity of wireless networks over fadingimprovement of ad hoc wireless networks using directionalThe capacity of wireless networks,” IEEE Trans. Inform.
On the short string limit of the folded spinning string in AdS5 x S5
M. Beccaria; A. Tirziu
2008-10-23T23:59:59.000Z
In this paper we generalize the results of arXiv:0806.4758 to non-zero value J of angular momentum in S^5. We compute the 1-loop correction to the energy of the folded spinning string in AdS_5 x S^5 in the particular limit of slow short string approximation. In this limit the string is moving in a near-flat central region of AdS_5 slowly rotating in both AdS_5 and S^5. The one-loop correction should represent the first subleading correction to strong coupling expansion of the anomalous dimension of short gauge theory operators of the form Tr D^S Z^J in the SL(2) sector.
Gaucher Disease Inherited disorder
Brutlag, Doug
, spleen, and bone marrow ¡ Many types ¡ Possible link to Parkinson's Disease ¡ Affects 1 in 100,000 #12/> ¡ "Gaucher Disease." Genetics Home Reference Your Guide to Understanding Genetic Conditions. US National Disease." Gene Review. Web 2 Oct. 2012. Genetics
Multipath Routing Based Secure Data Transmission in Ad Hoc Networks
Delgado-Frias, José G.
Multipath Routing Based Secure Data Transmission in Ad Hoc Networks Li Zhao and José G. Delgado in the networks. In this paper, we present and evaluate a scheme, in which multipath routing combined the single path DSR. Index Terms--security, data transmission, multipath routing, ad hoc networks I
Developing Louisiana's Forest Products Industry: Adding Value for the Future
of a manufacturingThe increased value at each stage of a manufacturing assembly processassembly process Those and necessaryimportant and necessary Addition of net economic valueAddition of net economic value Value can be added through manufacturing orValue can be added through manufacturing or marketingmarketing Why Add Value
Reception-Aware Power Control in Ad Hoc Mobile Networks
Mans, Bernard
Reception-Aware Power Control in Ad Hoc Mobile Networks Nirisha Shrestha and Bernard Mans Macquarie resource in ad hoc mobile networks, mak- ing power control a popular, yet crucial, technique. The network of power control non-trivial. For sake of simplicity, most existing power control protocols only consider
Poon, Chung Keung
________________________________________________________________________________ Topology Control of Ad Hoc Wireless Networks for Energy Efficiency Maggie X. Cheng, Member, IEEE, Mihaela of each wireless node such that the resulting network is connected and the total energy consumption the theoretical analysis. Index Terms--Multihop, ad hoc, wireless networks, energy efficiency, transmission power
Curriculum Revision REPORT OF AD HOC WORKING GROUP ON
Brown, Sally
Curriculum Revision REPORT OF AD HOC WORKING GROUP ON CURRICULUM REVISION (November 2002- March (2) Charge to Ad Hoc Working Group on Curriculum.............................. 12 (3) Materials;Curriculum Revision SUMMARY Curriculum transformation at the College of Forest Resources (CFR) is a response
Dynamics and BPS states of AdS5 supergravity with a Gauss-Bonnet term
Olivera Miskovic; Ricardo Troncoso; Jorge Zanelli
2006-03-23T23:59:59.000Z
Some dynamical aspects of five-dimensional supergravity as a Chern-Simons theory for the SU(2,2|N) group, are analyzed. The gravitational sector is described by the Einstein-Hilbert action with negative cosmological constant and a Gauss-Bonnet term with a fixed coupling. The interaction between matter and gravity is characterized by intricate couplings which give rise to dynamical features not present in standard theories. Depending on the location in phase space, the dynamics can possess different number of propagating degrees of freedom, including purely topological sectors. This inhomogeneity of phase space requires special care in the analysis. Background solutions in the canonical sectors, which have regular dynamics with maximal number of degrees of freedom, are shown to exist. Within this class, explicit solutions given by locally AdS spacetimes with nontrivial gauge fields are constructed, and BPS states are identified. It is shown that the charge algebra acquires a central extension due to the presence of the matter fields. The Bogomol'nyi bound for these charges is discussed. Special attention is devoted to the N=4 case since then the gauge group has a U(1) central charge and the phase space possesses additional irregular sectors.
Emergent AdS3 and BTZ Black Hole from Weakly Interacting Hot 2d CFT
Soo-Jong Rey; Yasuaki Hikida
2006-05-02T23:59:59.000Z
We investigate emergent holography of weakly coupled two-dimensional hyperK\\"ahler sigma model on cotangent bundle of (N-1)-dimensional complex projective space at zero and finite temperature. The sigma model is motivated by the spacetime conformal field theory dual to the near-horizon geometry of Q1 D1-brane bound to Q5 D5-brane wrapped on four-torus times circle, where N = Q1*Q5. The sigma model admits nontrivial instanton for all N greater than or equal to 2, which serves as a local probe of emergent holographic spacetime. We define emergent geometry of the spacetime as that of instanton moduli space via Hitchin's information metric. At zero temperature, we find that emergent geometry is AdS3. At finite temperature, time-periodic instanton is mappable to zero temperature instanton via conformal transformation. Utilizing the transformation, we show that emergent geometry is precisely that of the non-extremal, non-rotating BTZ black hole.
New Formulation of the Type IIB Superstring Action in $AdS_5 \\times S^5$
John H. Schwarz
2015-06-25T23:59:59.000Z
Previous studies of the type IIB superstring in an ${AdS_5 \\times S^5}$ background are based on a description of the superspace geometry as the quotient space $PSU(2,2|4)/SO(4,1) \\times SO(5)$. This paper develops an alternative approach in which the Grassmann coordinates provide a nonlinear realization of $PSU(2,2|4)$ based on the quotient space $PSU(2,2|4)/SU(2,2) \\times SU(4)$, and the bosonic coordinates are described as a submanifold of $SU(2,2) \\times SU(4)$. This formulation keeps all bosonic symmetries manifest, and it provides the complete dependence on the Grassmann coordinates in terms of simple analytic expressions. It is used to construct the superstring world-sheet action in a form in which the $PSU(2,2|4)$ symmetry is manifest and kappa symmetry can be established. This formulation might have some advantages compared to previous ones, but this remains to be demonstrated.
Classical and Quantum Equations of Motion for a BTZ Black String in AdS Space
Eric Greenwood; Evan Halstead; Peng Hao
2010-01-24T23:59:59.000Z
We investigate gravitational collapse of a $(3+1)$-dimensional BTZ black string in AdS space in the context of both classical and quantum mechanics. This is done by first deriving the conserved mass per unit length of the cylindrically symmetric domain wall, which is taken as the classical Hamiltonian of the black string. In the quantum mechanical context, we take primary interest in the behavior of the collapse near the horizon and near the origin (classical singularity) from the point of view of an infalling observer. In the absence of radiation, quantum effects near the horizon do not change the classical conclusions for an infalling observer, meaning that the horizon is not an obstacle for him/her. The most interesting quantum mechanical effect comes in when investigating near the origin. First, quantum effects are able to remove the classical singularity at the origin, since the wave function is non-singular at the origin. Second, the Schr\\"odinger equation describing the behavior near the origin displays non-local effects, which depend on the energy density of the domain wall. This is manifest in that derivatives of the wavefunction at one point are related to the value of the wavefunction at some other distant point.
An Integrable Deformation of the AdS5 x S5 Superstring
Timothy J. Hollowood; J. Luis Miramontes; David M. Schmidtt
2014-09-24T23:59:59.000Z
The S-matrix on the world-sheet theory of the string in AdS5 x S5 has previously been shown to admit a deformation where the symmetry algebra is replaced by the associated quantum group. The case where q is real has been identified as a particular deformation of the Green-Schwarz sigma model. An interpretation of the case with q a root of unity has, until now, been lacking. We show that the Green-Schwarz sigma model admits a discrete deformation which can be viewed as a rather simple deformation of the F/F_V gauged WZW model, where F=PSU(2,2|4). The deformation parameter q is then a k-th root of unity where k is the level. The deformed theory has the same equations-of-motion as the Green-Schwarz sigma model but has a different symplectic structure. We show that the resulting theory is integrable and has just the right amount of kappa-symmetries that appear as a remnant of the fermionic part of the original gauge symmetry. This points to the existence of a fully consistent deformed string background.
An Integrable Deformation of the AdS5 x S5 Superstring
Hollowood, Timothy J; Schmidtt, David
2014-01-01T23:59:59.000Z
The S-matrix on the world-sheet theory of the string in AdS5 x S5 has previously been shown to admit a deformation where the symmetry algebra is replaced by the associated quantum group. The case where q is real has been identified as a particular deformation of the Green-Schwarz sigma model. An interpretation of the case with q a root of unity has, until now, been lacking. We show that the Green-Schwarz sigma model admits a discrete deformation which can be viewed as a rather simple deformation of the F/F gauged WZW model, where F=PSU(2,2|4). The deformation parameter q is then a k-th root of unity where k is the level. The deformed theory has the same equations-of-motion as the Green-Schwarz sigma model but has a different symplectic structure. We show that the resulting theory is integrable and has just the right amount of kappa-symmetries that appear as a remnant of the fermionic part of the original gauge symmetry. This points to the existence of a fully consistent deformed string background.
Characteristic length of an AdS/CFT superconductor
Kengo Maeda; Takashi Okamura
2008-10-30T23:59:59.000Z
We investigate in more detail the holographic model of a superconductor recently found by Hartnoll, Herzog, and Horowitz [Phys. Rev. Lett. 101, 031601], which is constructed from a condensate of a charged scalar field in AdS_4-Schwarzschild background. By analytically studying the perturbation of the gravitational system near the critical temperature T_c, we obtain the superconducting coherence length proportional to 1/\\sqrt{1-T/T_c} via AdS/CFT correspondence. By adding a small external homogeneous magnetic field to the system, we find that a stationary diamagnetic current proportional to the square of the order parameter is induced by the magnetic field. These results agree with Ginzburg-Landau theory and strongly support the idea that a superconductor can be described by a charged scalar field on a black hole via AdS/CFT duality.
New $AdS_3 \\times S^2$ T-duals with $\\mathcal{N} = (0,4)$ supersymmetry
Yolanda Lozano; Niall T. Macpherson; Jesús Montero; Eoin Ó Colgáin
2015-07-09T23:59:59.000Z
It is well known that Hopf-fibre T-duality and uplift takes the D1-D5 near-horizon into a class of $AdS_3 \\times S^2$ geometries in 11D where the internal space is a Calabi-Yau three-fold. Moreover, supersymmetry dictates that Calabi-Yau is the only permissible $SU(3)$-structure manifold. Generalising this duality chain to non-Abelian isometries, a strong parallel exists, resulting in the first explicit example of a class of $AdS_3 \\times S^2$ geometries with $SU(2)$-structure. Furthermore, the non-Abelian T-dual of $AdS_3 \\times S^3 \\times S^3 \\times S^1$ results in a new supersymmetric $AdS_3 \\times S^2$ geometry, which falls outside of all known classifications. We explore the basic properties of the holographic duals associated to the new backgrounds. We compute the central charges and show that they are compatible with a large $\\mathcal{N}=4$ superconformal algebra in the infra-red.
A generalization of the Lax pair for the pure spinor superstring in AdS5 x S5
Andrei Mikhailov
2013-08-09T23:59:59.000Z
We show that the Lax pair of the pure spinor superstring in AdS5xS5 admits a generalization where the generators of the superconformal algebra are replaced by the generators of some infinite-dimensional Lie superalgebra.
A generalization of the Lax pair for the pure spinor superstring in AdS5 x S5
Mikhailov, Andrei
2013-01-01T23:59:59.000Z
We show that the Lax pair of the pure spinor superstring in AdS5xS5 admits a generalization where the generators of the superconformal algebra are replaced by the generators of some infinite-dimensional Lie superalgebra.
Yangian Symmetry, S-Matrices and Bethe Ansatz for the AdS5 x S5 Superstring
M de Leeuw
2009-01-22T23:59:59.000Z
We discuss the relation between the recently derived bound state S-matrices for the AdS5 x S5 superstring and Yangian symmetry. We will study the relation between this Yangian symmetry and the Bethe ansatz. In particular we can use it to derive the Bethe equations for bound states.
Baker, Chris I.
Kidney Disease of Diabetes National Kidney and Urologic Diseases Information Clearinghouse is the final stage of chronic kidney disease (CKD). Diabetes is the most common cause of kidney failure, accounting for nearly 44 percent of new cases.1 Even when diabetes is controlled, the disease can lead to CKD
Molecular Bioinformatics for Diseases
Radivojac, Predrag
. Curr Opin Pediatr, 13: 22 (2001). Leads to sickle cell anemia Manifestation of disease vastly different
Critical behavior of charged Gauss-Bonnet AdS black holes in the grand canonical ensemble
Zou, De-Cheng; Wang, Bin
2014-01-01T23:59:59.000Z
We study the thermodynamics in the grand canonical ensemble of D-dimensional charged Gauss-Bonnet-AdS black holes in the extended phase space. We find that the usual small-large black hole phase transition, which exhibits analogy with the Van de Waals liquid-gas system holds in five-dimensional spherical charged Gauss-Bonnet-AdS black holes when its potential is fixed within the range $0Gauss-Bonnet-AdS black holes, there is no such phase transition. In the limiting case, Reissner-Nordstrom-AdS black holes, with vanishing Gauss-Bonnet parameter, there is no critical behavior in the grand canonical ensemble. This result holds independent of the spacetime dimensions and topologies. We also examine the behavior of physical quantities in the vicinity of the critical point in the five-dimensional spherical charged Gauss-Bonnet-AdS black holes.
Critical behavior of charged Gauss-Bonnet AdS black holes in the grand canonical ensemble
De-Cheng Zou; Yunqi Liu; Bin Wang
2014-09-03T23:59:59.000Z
We study the thermodynamics in the grand canonical ensemble of D-dimensional charged Gauss-Bonnet-AdS black holes in the extended phase space. We find that the usual small-large black hole phase transition, which exhibits analogy with the Van de Waals liquid-gas system holds in five-dimensional spherical charged Gauss-Bonnet-AdS black holes when its potential is fixed within the range $0Gauss-Bonnet-AdS black holes, there is no such phase transition. In the limiting case, Reissner-Nordstrom-AdS black holes, with vanishing Gauss-Bonnet parameter, there is no critical behavior in the grand canonical ensemble. This result holds independent of the spacetime dimensions and topologies. We also examine the behavior of physical quantities in the vicinity of the critical point in the five-dimensional spherical charged Gauss-Bonnet-AdS black holes.
Paris-Sud XI, Université de
EDITORIAL Picturing the brain from different perspectives: the neuroimaging of early AD The last. The description of the clinical and cognitive signs of specific brain diseases, as well as our understanding of normal brain function have been considerably improved, thanks to research ranging from anatomoclinical
Noncommutative Extension of AdS-CFT and Holographic Superconductors
Souvik Pramanik; Sudipta Das; Subir Ghosh
2015-02-13T23:59:59.000Z
In this Letter, we consider a Non-Commutative (NC) extension of AdS-CFT correspondence and its effects on holographic superconductors. NC corrections are incorporated via the NC generalization of Schwarzschild black hole metric in AdS with the probe limit. We study NC effects on the relations connecting the charge density and the critical temperature of the Holographic Superconductors. Furthermore, condensation operator of the superconductor has been analyzed. Our results suggest that generically, NC effects increase the critical temperature of the holographic superconductor.
Fjell, Anders M.
Age is associated with substantial macrostructural brain changes. While some recent magnetic resonance imaging studies have reported larger age effects in men than women, others find no sex differences. As brain morphometry ...
Jaber, Ala'a Fayez
2010-05-31T23:59:59.000Z
Submitted to the graduate degree program in Occupational Therapy and the Graduate Faculty of the University of Kansas in partial fulfillment of the requirements for the degree of Master of Science... and extensive research expertise that helped me complete this project. To Eric Vidoni who helped me initiate and develop this project. To the faculty, staff, and students in the Occupational Therapy Education for their help and assistance...
A learning deficit related to age and b-amyloid plaques in a mouse model of Alzheimer's disease
Chen, Guiquan; Chen, Karen S; Knox, Jane H; Inglis, Jennifer; Bernard, Andrew; Martin, Stephen J; Justice, Alan; McConlogue, Lisa; Games, Dora; Freedman, Stephen B; Morris, Richard G M
2000-12-21T23:59:59.000Z
Mice that overexpress the human mutant amyloid precursor protein (hAPP) show learning deficits, but the apparent lack of a relationship between these deficits and the progressive b-amyloid plaque formation that the hAPP ...
2012-01-01T23:59:59.000Z
ters in the placebo group, seven in the 2 gm/day group, andsubjects in the placebo group, seven in the 2 gm/day group,
2012-01-01T23:59:59.000Z
in the 2 gm/day group, and eight in the 4 gm/day group. Twoin the 2 gm/day group, and for eight in the 4 gm/day group.
Li, Jing
-Modality Neuroimaging Data using Sparse Composite Linear Discrimination Analysis" I How does the formulation (5) serve
2008-01-01T23:59:59.000Z
also re- ported that resveratrol, a natural polyphe- nolP, Zhao H, Davies P (2005) Resveratrol promotes clearance of
Bangen, Katherine J.
2010-01-01T23:59:59.000Z
Framingham Stroke Risk Pro?le (FSRP; D’Agostino, et al. ,1994). The FSRP is a validated scale that was developed torisk burden. The FSRP provides gender-corrected scores based
Rodríguez, Mario Alfredo Parra
Memory binding is a cognitive process that enables complex objects to be stored or retrieved coherently during perception, learning, or action. Binding functions are aimed at reducing the misattribution of the features ...
Adding OAI-ORE Support to Repository Platforms
Maslov, Alexey; Mikeal, Adam; Phillips, Scott; Leggett, John; McFarland, Mark
2009-05-17T23:59:59.000Z
the local to the federated repository became evident. This paper presents our experiences adding harvesting support to the DSpace repository platform using the ORE and PMH protocols from the Open Archives Initiative. We describe our use case for a statewide...
Mobilized ad-hoc networks: A reinforcement learning approach
Chang, Yu-Han
2003-12-04T23:59:59.000Z
Research in mobile ad-hoc networks has focused on situations in which nodes have no control over their movements. We investigate an important but overlooked domain in which nodes do have control over their movements. ...
Missouri Value-Added Loan Guarantee Program (Missouri)
Broader source: Energy.gov [DOE]
The Missouri Value-Added Loan Guarantee Program provides a 50% first-loss guarantee to lenders who make agricultural business development loans for the acquisition, construction, improvement, or...
User level routing for mobile ad hoc networks
Virk, Navjot
2001-01-01T23:59:59.000Z
Many routing protocols have been proposed for mobile ad hoc networks. Traditionally routing protocols have been implemented in the kernel of the operating system. The main reasons for this are performance and security. This research explores...
Poster: -Graphs: Flexible Topology Control in Wireless Ad Hoc Networks
Williamson, Carey
Poster: -Graphs: Flexible Topology Control in Wireless Ad Hoc Networks Ashikur Rahman Department networks. Most algorithms strive to reduce energy consumption by cre- ating a sparse topology with few long of topologies and provides the flexibility to network
Truthful resource management in wireless ad hoc networks
Cai, Jianfeng
2005-11-01T23:59:59.000Z
In wireless mobile ad hoc networks (MANETs), cooperation cannot be an im- plicit assumption anymore. Each profit-oriented network node has the intention to be selfish due to limited resource possession. In this dissertation, we investigate...
Context-Aware Protocol Engines for Ad Hoc Networks
Garcia-Luna-Aceves, J.J.
2009-01-01T23:59:59.000Z
Context-Aware Protocol Engines for Ad Hoc Networks J. J.we call a context-aware protocol engine. With a CAPE, nodesthe context-aware protocol engine (CAPE) as an instantiation
Fighting Online Click-Fraud Using Bluff Ads
Haddadi, Hamed
2010-01-01T23:59:59.000Z
Online advertising is currently the greatest source of revenue for many Internet giants. The increased number of specialized websites and modern profiling techniques, have all contributed to an explosion of the income of ad brokers from online advertising. The single biggest threat to this growth, is however, click-fraud. Trained botnets and even individuals are hired by click-fraud specialists in order to maximize the revenue of certain users from the ads they publish on their websites, or to launch an attack between competing businesses. In this note we wish to raise the awareness of the networking research community on potential research areas within this emerging field. As an example strategy, we present Bluff ads; a class of ads that join forces in order to increase the effort level for click-fraud spammers. Bluff ads are either targeted ads, with irrelevant display text, or highly relevant display text, with irrelevant targeting information. They act as a litmus test for the legitimacy of the individual...
Interim Chronic Beryllium Disease
Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]
1999-12-08T23:59:59.000Z
Establishes Departmental expectations for addressing chronic beryllium disease throughout the Department until a Departmental rule on beryllium is promulgated. This Notice was replaced by final rule 10 CFR Part 850, Chronic Beryllium Disease Prevention Program, published December 8, 1999.
Texas Plant Diseases Handbook.
Horne, C. Wendell; Amador, Jose M.; Johnson, Jerral D.; McCoy, Norman L.; Philley, George L.; Lee, Thomas A. Jr.; Kaufman, Harold W.; Jones, Roger K.; Barnes, Larry W.; Black, Mark C.
1988-01-01T23:59:59.000Z
Background The first step in evaluating potential geographic clusters of disease calls for an evaluation of the disease risk comparing the risk in a defined location to the risk in neighboring locations. Environmental ...
Chaotic strings in a near Penrose limit of AdS$_5\\times T^{1,1}$
Yuhma Asano; Daisuke Kawai; Hideki Kyono; Kentaroh Yoshida
2015-07-17T23:59:59.000Z
We study chaotic motions of a classical string in a near Penrose limit of AdS$_5\\times T^{1,1}$. It is known that chaotic solutions appear on $R\\times T^{1,1}$, depending on initial conditions. It may be interesting to ask whether the chaos persists even in Penrose limits or not. In this paper, we show that sub-leading corrections in a Penrose limit provide an unstable separatrix, so that chaotic motions are generated as a consequence of collapsed Kolmogorov-Arnold-Moser (KAM) tori. Our analysis is based on deriving a reduced system composed of two degrees of freedom by supposing a winding string ansatz. Then, we provide support for the existence of chaos by computing Poincare sections. In comparison to the AdS$_5\\times T^{1,1}$ case, we argue that no chaos lives in a near Penrose limit of AdS$_5\\times$S$^5$, as expected from the classical integrability of the parent system.
AdS/CFT and Exclusive Processes in QCD
Stanley J. Brodsky; Guy F. de Teramond
2007-09-13T23:59:59.000Z
The AdS/CFT correspondence between string theory in AdS space and conformal field theories in physical space-time leads to an analytic, semi-classical model for strongly-coupled QCD which has scale invariance and dimensional counting at short distances and color confinement at large distances. One can use holography to map the amplitude describing the hadronic state in the fifth dimension of Anti-de Sitter space to the light-front wavefunctions of hadrons in physical space-time, thus providing a relativistic description of hadrons in QCD at the amplitude level. In particular, we show that there is an exact correspondence between the fifth-dimensional coordinate of AdS space z and a specific impact variable zeta which measures the separation of the quark and gluonic constituents within the hadron in ordinary space-time. New relativistic light-front equations in ordinary space-time can then be derived which reproduce the results obtained using the 5-dimensional theory. The effective light-front equations possess elegant algebraic structures and integrability properties. This connection between the AdS and the light-front representations allows one to compute the analytic form of the frame-independent light-front wavefunctions, the fundamental entities which encode hadron properties and allow the computation of decay constants, form factors, deeply virtual Compton scattering, exclusive heavy hadron decays and other exclusive scattering amplitudes. As specific examples we compute the pion coupling constant and study the behavior of the pion form factor in the space and time-like regions. We also determine the Dirac form factors of the proton and neutron in the space-like region.
Topology Control Protocols to Conserve Energy in Wireless Ad Hoc Networks
Xu, Ya; Bien, Solomon; Mori, Yutaka; Heidemann, John; Estrin, D
2003-01-01T23:59:59.000Z
Protocols to Conserve Energy in Wireless Ad Hoc Networks YaL. Tassiulas. Energy conserving routing in wireless ad-hocAdaptive Energy Conservation Protocols for Wireless Ad Hoc
Process and targets for production of no-carrier-added radiotin
Srivastava, Suresh C; Zhuikov, Boris Leonidovich; Ermolaev, Stanislav Victorovich; Konyakhin, Nikolay Alexandrovich; Kokhanyuk, Vladimir Mikhailovich; Khamyanov, Stepan Vladimirovich; Togaeva, Natalya Roaldovna
2014-04-22T23:59:59.000Z
One embodiment of the present invention includes a process for production and recovery of no-carrier-added radioactive tin (NCA radiotin). An antimony target can be irradiated with a beam of accelerated particles forming NCA radiotin, followed by separation of the NCA radiotin from the irradiated target. The target is metallic Sb in a hermetically sealed shell. The shell can be graphite, molybdenum, or stainless steel. The irradiated target can be removed from the shell by chemical or mechanical means, and dissolved in an acidic solution. Sb can be removed from the dissolved irradiated target by extraction. NCA radiotin can be separated from the remaining Sb and other impurities using chromatography on silica gel sorbent. NCA tin-117m can be obtained from this process. NCA tin-117m can be used for labeling organic compounds and biological objects to be applied in medicine for imaging and therapy of various diseases.
Morimoto, Richard
Amyotrophic Lateral Sclerosis (ALS), at least nine CAG-repeat diseases, Alzheimer disease (AD), and Parkinson aggregation is implicated in numerous diseases. Results: Polyglutamine oligomers maintain a heterogeneous distribution that reaches an equilibrium during aging and can be altered by genetic modifiers that suppress
Caldwell, Guy
such as Parkinson dis- ease, Alzheimer disease (AD), amyotrophic lateral sclerosis (ALS), and frontotemporal lobar, -sy- nuclein ( -syn) aggregates can be observed in most cases of Parkinson disease, multiple systems: Expressing TDP-43 in yeast mimics several aspects of human TDP-43-based neurodegenerative diseases. Results
[16] Modeling Polyglutamine Pathogenesis in C. elegans
Morimoto, Richard
including Alzheimer's disease (AD), Parkinson's disease (PD), prion disorders, amyotrophic lateral sclerosis*, SUSANA M. GARCIA, and RICHARD I. MORIMOTO Abstract A growing number of human neurodegenerative diseases these disorders, bringing the many advantages of such systems, particularly the power of genetic analysis
The Capacityand Energy Efficiency of Wireless Ad Hoc Networks with MultipacketReception
Garcia-Luna-Aceves, J.J.
2008-01-01T23:59:59.000Z
per-joule capacity of energy-limited wireless networks. IEEECapacity and Energy Efficiency of Wireless Ad Hoc Networksplexity, and energy efficiency in random wireless ad hoc
Top Value Added Chemicals from Biomass: Volume I--Results of...
Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site
Top Value Added Chemicals from Biomass: Volume I--Results of Screening for Potential Candidates from Sugars and Synthesis Gas Top Value Added Chemicals from Biomass: Volume...
Androutsopoulos, Vasilis P. [Center of Toxicology Science and Research, University of Crete, Heraklion, Crete (Greece)] [Center of Toxicology Science and Research, University of Crete, Heraklion, Crete (Greece); Kanavouras, Konstantinos [Laboratory of Neurological Sciences, University of Crete, Heraklion, Crete (Greece)] [Laboratory of Neurological Sciences, University of Crete, Heraklion, Crete (Greece); Tsatsakis, Aristidis M., E-mail: aris@med.uoc.gr [Center of Toxicology Science and Research, University of Crete, Heraklion, Crete (Greece)
2011-11-15T23:59:59.000Z
Organophosphate pesticides are a class of compounds that are widely used in agricultural and rural areas. Paraoxonase 1 (PON1) is a phase-I enzyme that is involved in the hydrolysis of organophosphate esters. Environmental poisoning by organophosphate compounds has been the main driving force of previous research on PON1 enzymes. Recent discoveries in animal models have revealed the important role of the enzyme in lipid metabolism. However although PON1 function is well established in experimental models, the contribution of PON1 in neurodegenerative diseases remains unclear. In this minireview we summarize the involvement of PON1 genotypes in the occurrence of Parkinson's disease, Alzheimer's disease and amyotrophic lateral sclerosis. A brief overview of latest epidemiological studies, regarding the two most important PON1 coding region polymorphisms PON1-L55M and PON1-Q192R is presented. Positive and negative associations of PON1 with disease occurrence are reported. Notably the MM and RR alleles contribute a risk enhancing effect for the development of some neurodegenerative diseases, which may be explained by the reduced lipoprotein free radical scavenging activity that may give rise to neuronal damage, through distinct mechanism. Conflicting findings that fail to support this postulate may represent the human population ethnic heterogeneity, different sample size and environmental parameters affecting PON1 status. We conclude that further epidemiological studies are required in order to address the exact contribution of PON1 genome in combination with organophosphate exposure in populations with neurodegenerative diseases.
No-carrier-added [1.sup.11 c]putrescine
McPherson, Daniel W. (Baltimore, MD); Fowler, Joanna S. (Bellport, NY); Wolf, Alfred P. (Setauket, NY)
1989-01-01T23:59:59.000Z
The invention relates to a new radiolabeled imaging agent, no-carrier-added [1-.sup.11 C]putrescine, and to the use of this very pure material as a radiotracer with positron emission tomography for imaging brain tumors. The invention further relates to the synthesis of no-carrier-added [1-.sup.11 C]putrescine based on the Michael addition of potassium .sup.11 C-labeled cyanide to acrylonitrile followed by reduction of the .sup.11 C-labeled dinitrile. The new method is rapid and efficient and provides radiotracer with a specific activity greater than 1.4 curies per millimol and in a purity greater than 95%.
Nucleon and flavor form factors in AdS/QCD
Chakrabarti, Dipankar
2013-01-01T23:59:59.000Z
The electromagnetic form factors for the nucleons are related with the GPDs by sum rules. Using the sum rules we calculate the valence GPDs for $u$ and $d$ quarks in a quark model using the lightfront wavefunctions for the nucleons obtained from AdS/QCD. The flavor decompositions of the nucleon form factors are also calculated from the GPDs in this model. We show that the nucleon form factors and their flavor decompositions calculated in AdS/QCD are in agreement with experimental data.
Non-extended phase space thermodynamics of Lovelock AdS black holes in grand canonical ensemble
Jie-Xiong Mo; Wen-Biao Liu
2015-03-06T23:59:59.000Z
Recently, extended phase space thermodynamics of Lovelock AdS black holes has been of great interest. To provide insight from a different perspective and gain a unified phase transition picture, non-extended phase space thermodynamics of $(n+1)$-dimensional charged topological Lovelock AdS black holes is investigated detailedly in the grand canonical ensemble. Specifically, the specific heat at constant electric potential is calculated and phase transition in the grand canonical ensemble is discussed. To probe the impact of the various parameters, we utilize the control variate method and solve the phase transition condition equation numerically for the case $k=1,-1$. There are two critical points for the case $n=6,k=1$ while there is only one for other cases. For $k=0$, there exists no phase transition point. To figure out the nature of phase transition in the grand canonical ensemble, we carry out an analytic check of the analog form of Ehrenfest equations proposed by Banerjee et al. It is shown that Lovelock AdS black holes in the grand canonical ensemble undergo a second order phase transition. To examine the phase structure in the grand canonical ensemble, we utilize the thermodynamic geometry method and calculate both the Weinhold metric and Ruppeiner metric. It is shown that for both analytic and graphical results that the divergence structure of the Ruppeiner scalar curvature coincides with that of the specific heat. Our research provides one more example that Ruppeiner metric serves as a wonderful tool to probe the phase structures of black holes.
A $\\mathcal{N}=2$ Supersymmetric $AdS_4$ Solution in M-theory with Purely Magnetic Flux
Yolanda Lozano; Niall T. Macpherson; Jesús Montero
2015-07-10T23:59:59.000Z
We find a new $\\mathcal{N}=2$ $AdS_4$ solution in M-theory supported by purely magnetic flux via a sequence of abelian and non-abelian T-dualities. This provides the second known example in this class besides the uplift of the Pernici and Sezgin solution to 7d gauged supergravity constructed in the eighties. We compute the free energy of the solution, and show that it scales as $N^{3/2}$. It is intriguing that even though the natural holographic interpretation is in terms of M5-branes wrapped on a special Lagrangian 3-cycle, this solution does not exhibit the expected $N^3$ behavior.
$P-V$ criticality of AdS black hole in the Einstein-Maxwell-power-Yang-Mills gravity
Ming Zhang; Zhan-Ying Yang; De-Cheng Zou; Wei Xu; Rui-Hong Yue
2014-12-03T23:59:59.000Z
We study the $P-V$ critical behaivor of N-dimensional AdS black holes in Einstein-Maxwell-power-Yang-Mills gravity. Our results show the existence of the Van der Waals like small-large black hole phase transitions when taking some special values of charges of the Maxwell and Yang-Mills (YM) fields. Further to calculate the critical exponents of the black holes at the critical point, we find that they are the same as those in the Van der Waals liquid-gas system.
Bound States of the q-Deformed AdS5 x S5 Superstring S-matrix
Ben Hoare; Timothy J. Hollowood; J. Luis Miramontes
2012-05-31T23:59:59.000Z
The investigation of the q deformation of the S-matrix for excitations on the string world sheet in AdS5 x S5 is continued. We argue that due to the lack of Lorentz invariance the situation is more subtle than in a relativistic theory in that the nature of bound states depends on their momentum. At low enough momentum |p|1. This subtlety fixes a problem involving the consistency of crossing symmetry with the relativistic limit found in earlier work. With mirror kinematics, obtained after a double Wick rotation, the bound state structure is simpler and there are no marginally unstable bound states.
Bound States of the q-Deformed AdS5 x S5 Superstring S-matrix
Hoare, Ben; Miramontes, J Luis
2012-01-01T23:59:59.000Z
The investigation of the q deformation of the S-matrix for excitations on the string world sheet in AdS5 x S5 is continued. We argue that due to the lack of Lorentz invariance the situation is more subtle than in a relativistic theory in that the nature of bound states depends on their momentum. At low enough momentum |p|1. This subtlety fixes a problem involving the consistency of crossing symmetry with the relativistic limit found in earlier work. With mirror kinematics, obtained after a double Wick rotation, the bound state structure is simpler and there are no marginally unstable bound states.
Modular Anomaly Detection for Smartphone Ad hoc Communication
of the security solution is evaluated in a small testbed based on three Android-based handsets and a laptop a mobile ad hoc network (MANET). While intrusion detection in MANETs is typically evaluated with network simulators, we argue that it is important to implement and test the solutions in real de- vices to evaluate
Adding Parallel I/O to PARA-BMU
Johnson, Nick; Bethune, Iain
2012-10-01T23:59:59.000Z
VOX-FE is a voxel-based bone modelling suite. The solver part of the suite - PARA-BMU - currently uses only serial I/O routines which lead to poor scalability. We enhance the code by adding parallel I/O routines based on the netCDF and HDF5...
Drug Information Chart Notes Drug ad (intrinsic bias)
Fletcher, Robin
Drug Information Chart Notes Drug ad (intrinsic bias) Trade name Different for each company Dosage Same or different? A drug in a different dosage can be used for a different therapy. Precautions Check for pregnancy A complete book on drugs in pregnancy and lactation in bibliography. (unbiased
Building Intelligent Environments By Adding Smart Artifacts to Spaces
Loke, Seng W. - Loke, Seng W.
Building Intelligent Environments By Adding Smart Artifacts to Spaces: a Peer-to-Peer Architecture collections of smart artifacts, each artifact with an embedded processor, networking and sensing capabilities. The interactive capabilities of the environment are due to the collective working of the smart artifacts
Raman Lidar Profiles–Temperature (RLPROFTEMP) Value-Added Product
Newsom, RK; Sivaraman, C; McFarlane, SA
2012-10-31T23:59:59.000Z
The purpose of this document is to describe the Raman Lidar Profiles–Temperature (RLPROFTEMP) value-added product (VAP) and the procedures used to derive atmospheric temperature profiles from the raw RL measurements. Sections 2 and 4 describe the input and output variables, respectively. Section 3 discusses the theory behind the measurement and the details of the algorithm, including calibration and overlap correction.
AdSplit: Separating smartphone advertising from applications Shashi Shekhar
Wallach, Dan
AdSplit: Separating smartphone advertising from applications Shashi Shekhar shashi applications today rely on third-party advertising services, which provide libraries that are linked into the hosting application. This situ- ation is undesirable for both the application author and the advertiser
Shipboard lighting: A.D. 400-1900
Quinn, Kendra LeeAnne
1999-01-01T23:59:59.000Z
From A.D. 400-1900, illumination was gained by simply lighting a fibrous wick soaked in a burnable fuel. Yet, this basic technology played an integral part in the every day functioning of ships. Vessels which either sailed through the night...
Institute for Software Technology Ad anced RoboticsAdvanced Robotics
Institute for Software Technology Ad anced RoboticsAdvanced Robotics Human Robot Interaction Gerald Steinbauer Institute for Software Technology Gerald Steinbauer 1 Advanced Robotics Â Human Robot Interaction #12;Institute for Software Technology Motivation lik t h b t th tÂ· we like to have robots
An Energy Efficient Location Service for Mobile Ad Hoc etworks
Varela, Carlos
the distance traveled by the location update and query packets and, thus, at reducing the overall energy cost by the location update and query packets and, thus, to reduce the overall energy cost. 2 Energy Efficient LocationAn Energy Efficient Location Service for Mobile Ad Hoc etworks Zijian Wang1 , Eyuphan Bulut1
Wood Products Marketing And Value-Added Opportunities
Wood Products Marketing And Value-Added Opportunities In Latin America: A Focus on Brazil Richard Vlosky, Ph.D. Professor-Forest Products Marketing Interim Director-Louisiana Forest Products Laboratory Industry Strategic Services & Publisher: WOOD Markets Monthly newsletter WOOD Markets 2002 - The Solid Wood
Wood Products Marketing And Value-Added Opportunities
Wood Products Marketing And Value-Added Opportunities Richard Vlosky, Ph.D. Professor-Forest Products Marketing Interim Director-Louisiana Forest Products Laboratory School of Renewable Natural, R.E. Taylor & Associates Ltd. Forest Industry Strategic Services & Publisher: WOOD Markets Monthly
Cooperative Cache-Based Data Access in Ad Hoc Networks
Yener, Aylin
1 Cooperative Cache-Based Data Access in Ad Hoc Networks Guohong Cao, Liangzhong Yin and Chita R: Cooperative cache-based data access framework #12;6 Data Access Framework The cooperative cache-based data data authentication based on sensitivity. #12;16 Conclusion A cooperative cache-based data access
1 Antenna Beamforming and Power Control for Ad Hoc Networks
Ramanathan, Ram
1 Antenna Beamforming and Power Control for Ad Hoc Networks RAM RAMANATHAN BBN Technologies power, spreading code, and antenna beams. By controlling these transceiver parameters adaptively, coding, etc.) can also yield benefits, we shall focus on antenna and power control as they have been
A Power Control MAC Protocol for Ad Hoc Networks
A Power Control MAC Protocol for Ad Hoc Networks Eun-Sun Jung Dept. of Computer Science Texas A This paper presents a power control MAC protocol that al- lows nodes to vary transmit power level on a per control. The main idea of these power control schemes is to use different power lev- els for RTS
Operational Risk Management: Added Value of Advanced Methodologies
Maume-Deschamps, VÃ©ronique
Operational Risk Management: Added Value of Advanced Methodologies Paris, September 2013 Bertrand HASSANI Head of Major Risks Management & Scenario Analysis Santander UK Disclaimer: The opinions, ideas Measurement Key statements 1. Risk management moto: Si Vis Pacem Para Belum 1. Awareness 2. Prevention 3
Smart Services for Ad Hoc Databases University of Washington
Matrajt, Graciela
data-base from lists of addresses of nearby schools, locations of resources (e.g., ambulances), and contact information for emergency workers. · A consulting business analyst assembles an ad hoc data- base of commercial database management systems are prohibitive, especially without access to dedicated IT staff
Fusion for AdS/CFT boundary S-matrices
Rafael I. Nepomechie; Rodrigo A. Pimenta
2015-09-14T23:59:59.000Z
We propose a fusion formula for AdS/CFT worldsheet boundary S-matrices. We show that, starting from the fundamental Y=0 boundary S-matrix, this formula correctly reproduces the two-particle bound-state boundary S-matrices.
Adding Semantics to Data-Driven Paraphrasing Ellie Pavlick1
Plotkin, Joshua B.
minimal/significant husband/marry to found/party clean/cleanse tower/building boy/young girl oil/oil priceAdding Semantics to Data-Driven Paraphrasing Ellie Pavlick1 Johan Bos2 Malvina Nissim2 Charley (Figure 1). In contrast, data-driving paraphrasing typically sidesteps de- veloping a clear definition
Reducing the Energy Drain in Multihop Ad Hoc Geraud Allard
Mans, Bernard
that save energy of nodes with low battery but also allow the network to handle more flows. I. INTRODUCTION-efficient routing for Multihop Ad Hoc Networks (MANET) look at extend- ing battery life by minimizing the cost's shortest path algorithm in which we integrate the notion of remaining energy in order to satisfy flow
Real-Time Bid Optimization for Group-Buying Ads
Balakrishnan, Raju
2012-01-01T23:59:59.000Z
Group-buying ads seeking a minimum number of customers before the deal expiry are increasingly used by the daily-deal providers. Unlike the traditional web ads, the advertiser's profits for group-buying ads depends on the time to expiry and additional customers needed to satisfy the minimum group size. Since both these quantities are time-dependent, optimal bid amounts to maximize profits change with every impression. Consequently, traditional static bidding strategies are far from optimal. Instead, bid values need to be optimized in real-time to maximize expected bidder profits. This online optimization of deal profits is made possible by the advent of ad exchanges offering real-time (spot) bidding. To this end, we propose a real-time bidding strategy for group-buying deals based on the online optimization of bid values. We derive the expected bidder profit of deals as a function of the bid amounts, and dynamically vary bids to maximize profits. Further, to satisfy time constraints of the online bidding, we ...
Energy-Efficient Topology Control in Cooperative Ad Hoc Networks
Wang, Yu
Energy-Efficient Topology Control in Cooperative Ad Hoc Networks Ying Zhu, Minsu Huang, Siyuan Chen cooperative energy spanners in which the energy efficiency of individual paths are guaranteed. Both proposed of cooperative communication in various wireless network applications: energy efficient routing [23], [24], [25
Limited Flooding Protocol for Mobile Ad hoc Networks Mieso Denko
Goddard, Wayne
Limited Flooding Protocol for Mobile Ad hoc Networks Mieso Denko Department of Computing propose a multipath routing protocol called Limited Flooding. The protocol is fully reactive and does not entail the compu- tation of routing tables. It uses the basic features of flooding but restricts packet
Topping Turbines: Adding New Life to Older Plants
Cadrecha, M.
1984-01-01T23:59:59.000Z
the Sixth Annual Industrial Energy Technology Conference Volume II, Houston, TX, April 15-18, 1984 TOPPING TURBINES: ADDING NEW LIFE TO OLDER PLANTS Manuel Cadrecha, Ebasco Services, Inc., Atlanta. Georgia ARSTRlICT Ane~istingpower plant can be repowered...
A Study to Determine the Energy Impact of Adding Polarshield to Air Conditioning Systems
Cromer, C. J.
2001-01-01T23:59:59.000Z
. COA was added, one on a 5 ton older unit where 2.5 oz. COA was added, and a third on the same 5 ton unit where an additional 2.5 oz. COA was added to total 5.0 oz added to the system. The heat and humidity loads were carefully held constant...
1 Introduzione 5 2 La Fisica dei Quark Pesanti ad HERA 7
calorimetro ad uranio--scintillatore (CAL) . . . . . . . . . . . . . . . 35 4.3.1 Risoluzione energetica e
Non-extended phase space thermodynamics of Lovelock AdS black holes in grand canonical ensemble
Mo, Jie-Xiong
2015-01-01T23:59:59.000Z
Recently, extended phase space thermodynamics of Lovelock AdS black holes has been of great interest. To provide insight from a different perspective and gain a unified phase transition picture, non-extended phase space thermodynamics of $(n+1)$-dimensional charged topological Lovelock AdS black holes is investigated detailedly in the grand canonical ensemble. Specifically, the specific heat at constant electric potential is calculated and phase transition in the grand canonical ensemble is discussed. To probe the impact of the various parameters, we utilize the control variate method and solve the phase transition condition equation numerically for the case $k=1,-1$. There are two critical points for the case $n=6,k=1$ while there is only one for other cases. For $k=0$, there exists no phase transition point. To figure out the nature of phase transition in the grand canonical ensemble, we carry out an analytic check of the analog form of Ehrenfest equations proposed by Banerjee et al. It is shown that Lovelo...
Some Recent Progress in AdS/CFT
John H. Schwarz
2010-06-08T23:59:59.000Z
Much of modern string theory research concerns AdS/CFT duality, or more generally, gauge/gravity duality. The main subjects are a) Testing and understanding such dualities by exploring how they work for systems with a lot of supersymmetry b) Constructing and exploring approximate string theory duals of QCD c) Applying gauge/gravity duality to other areas of physics such as condensed matter and nuclear physics. I will briefly discuss the first topic.
Organic Aerosol Component (OACOMP) Value-Added Product Report
Fast, J; Zhang, Q; Tilp, A; Shippert, T; Parworth, C; Mei, F
2013-08-23T23:59:59.000Z
Significantly improved returns in their aerosol chemistry data can be achieved via the development of a value-added product (VAP) of deriving OA components, called Organic Aerosol Components (OACOMP). OACOMP is primarily based on multivariate analysis of the measured organic mass spectral matrix. The key outputs of OACOMP are the concentration time series and the mass spectra of OA factors that are associated with distinct sources, formation and evolution processes, and physicochemical properties.
Shuchi Energy Ad Promotions P Ltd | Open Energy Information
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onsource History View New PagessourceRavenand Some Initial ResultsShelbyShorewood Hills,Shuchi Energy Ad Promotions P Ltd
ARM Value-Added Cloud Products: Description and Status
Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:5 TablesExports(Journal Article)41cloth Documentation Data ManagementProductswsicloudwsicloudsummary Documentation Data Management8Data6454063Value-Added
A Platform for Implementing Secure Wireless Ad Hoc Networks
Farkas, Gyula; Haller, Piroska
2010-01-01T23:59:59.000Z
We propose a new platform for implementing secure wireless ad hoc networks. Our proposal is based on a modular architecture, with the software stack constructed directly on the Ethernet layer. Within our platform we use a new security protocol that we designed to ensure mutual authentication between nodes and a secure key exchange. The correctness of the proposed security protocol is ensured by Guttman's authentication tests.
Label-Free Quantitative LC?MS Proteomics of Alzheimer&rsquo...
Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)
(p-values <0.05, corrected for multiplicity of testing) in AD versus control brain samples. Thirty-seven of these proteins were reported as differentially abundant or...
A Natural Language for AdS/CFT Correlators
Fitzpatrick, A.Liam; /Boston U.; Kaplan, Jared; /SLAC; Penedones, Joao; /Perimeter Inst. Theor. Phys.; Raju, Suvrat; /Harish-Chandra Res. Inst.; van Rees, Balt C.; /YITP, Stony Brook
2012-02-14T23:59:59.000Z
We provide dramatic evidence that 'Mellin space' is the natural home for correlation functions in CFTs with weakly coupled bulk duals. In Mellin space, CFT correlators have poles corresponding to an OPE decomposition into 'left' and 'right' sub-correlators, in direct analogy with the factorization channels of scattering amplitudes. In the regime where these correlators can be computed by tree level Witten diagrams in AdS, we derive an explicit formula for the residues of Mellin amplitudes at the corresponding factorization poles, and we use the conformal Casimir to show that these amplitudes obey algebraic finite difference equations. By analyzing the recursive structure of our factorization formula we obtain simple diagrammatic rules for the construction of Mellin amplitudes corresponding to tree-level Witten diagrams in any bulk scalar theory. We prove the diagrammatic rules using our finite difference equations. Finally, we show that our factorization formula and our diagrammatic rules morph into the flat space S-Matrix of the bulk theory, reproducing the usual Feynman rules, when we take the flat space limit of AdS/CFT. Throughout we emphasize a deep analogy with the properties of flat space scattering amplitudes in momentum space, which suggests that the Mellin amplitude may provide a holographic definition of the flat space S-Matrix.
Adventures in Infectious Diseases
Fisher-Hoch, Susan [University of Texas School of Public Health
2014-06-25T23:59:59.000Z
Dr. Susan Fisher-Hoch, Virologist and Epidemiologist, will discuss her research and travels associated with viral hemorrhagic fevers. From the Ebola outbreak in Reston, Virginia to outbreaks of Crimean Congo Hemorrhagic Fever in South Africa, Senegal, and Saudi Arabia, Dr. Fisher-Hoch has studied and tracked the pathophysiology of these viral diseases. These studies have led her from the Center for Disease Control in the United States, to Lyon, France where she was instrumental in designing, constructing, and rendering operational a laboratory capable of containing some of the world's most dangerous diseases.
Chronic obstructive pulmonary disease, pulmonary function and cardiovascular disease
McAllister, David Anthony
2011-07-05T23:59:59.000Z
Cardiovascular disease is common in Chronic Obstructive Pulmonary Disease (COPD), and forced expiratory volume in one second (FEV1) independently predicts cardiovascular morbidity and mortality. Pathological changes in ...
Derivation of the action and symmetries of the q-deformed AdS_5 x S^5 superstring
Francois Delduc; Marc Magro; Benoit Vicedo
2014-09-01T23:59:59.000Z
We recently proposed an integrable q-deformation of the AdS_5 x S^5 superstring action. Here we give details on the hamiltonian origin and construction of this deformation. The procedure is a generalization of the one previously developed for deforming principal chiral and symmetric space sigma-models. We also show that the original psu(2,2|4) symmetry is replaced in the deformed theory by a classical analog of the quantum group U_q(psu(2,2|4)) with q real. The relation between q and the deformation parameter entering the action is given. The framework used to derive the deformation also enables to prove that at the hamiltonian level, the "maximal deformation" limit corresponds to an undeformed semi-symmetric space sigma-model with bosonic part dS_5 x H^5. Finally, we discuss the various freedoms in the construction.
On the Central Charge of Spacetime Current Algebras and Correlators in String Theory on AdS3
Porrati, Massimo
2015-01-01T23:59:59.000Z
Spacetime Virasoro and affine Lie algebras for strings propagating in AdS3 are known to all orders in $\\alpha'$. The central extension of such algebras is a string vertex, whose expectation value can depend on the number of long strings present in the background but should be otherwise state-independent. In hep-th/0106004, on the other hand, a state-dependent expectation value was found. Another puzzling feature of the theory is lack of cluster decomposition property in certain connected correlators. This note shows that both problems can be removed by defining the free energy of the spacetime boundary conformal field theory as the Legendre transform of the formula proposed in the literature. This corresponds to pass from a canonical ensemble, where the number of fundamental strings that create the background can fluctuate, to a microcanonical one, where it is fixed.
A. Belhaj; M. Chabab; H. EL Moumni; K. Masmar; M. B. Sedra
2015-07-01T23:59:59.000Z
Interpreting the cosmological constant as a thermodynamic pressure and its conjugate quantity as a thermodynamic volume, we reconsider the investigation of P-V critical behaviors of (1+n)-dimensional topological AdS black holes in Lovelock-Born-Infeld gravity. In particular, we give an explicit expression of the universal number \\chi=\\frac{P_c v_c}{T_c} in terms of the space dimension $n$. Then, we examine the phase transitions at the critical points of such topological black holes for 6 \\leq n \\leq 11 as required by the physical condition of the thermodynamical quantities. More precisely, the Ehrenfest equations have been checked revealing that the black hole system undergoes a second phase transition at the critical points.
Non-perturbative Effects in AdS5 * S5 String Theory and d=4 SUSY Yang-Mills
Tom Banks; Michael B. Green
1998-06-10T23:59:59.000Z
We show that five-dimensional anti de-Sitter space remains a solution to low-energy type IIB supergravity when the leading higher-derivative corrections to the classical supergravity (which are non-perturbative in the string coupling) are included. Furthermore, at this order in the low energy expansion of the IIB theory the graviton two-point and three-point functions in $AdS_5 \\times S^5$ are shown not to be renormalized and a precise expression is obtained for the four-graviton and related S-matrix elements. By invoking Maldacena's conjectured connection between IIB superstring theory and supersymmetric Yang-Mills theory corresponding statements are obtained concerning correlation functions of the energy-momentum tensor and related operators in the large-N Yang-Mills theory. This leads to interesting non-perturbative statements and insights into the r\\^ole of instantons in the gauge theory.
Bound States, Yangian Symmetry and Classical r-matrix for the AdS5 x S5 Superstring
M de Leeuw
2009-10-06T23:59:59.000Z
We show that the recently found S-matrices describing the scattering of two-particle bound states of the light-cone string sigma model on AdS5 x S5 are compatible with Yangian symmetry. In case the invariance with respect to the centrally extended su(2|2) algebra is not sufficient to fully specify the scattering matrix, the requirement of Yangian symmetry provides an alternative to the Yang-Baxter equation and leads to a complete, up to an overall phase, determination of the S-matrix. We then compare the semi-classical limit of the bound state S-matrices with the universal classical r-matrix by Beisert and Spill evaluated in the corresponding bound state representations and find perfect agreement.
Large scale disease prediction
Schmid, Patrick R. (Patrick Raphael)
2008-01-01T23:59:59.000Z
The objective of this thesis is to present the foundation of an automated large-scale disease prediction system. Unlike previous work that has typically focused on a small self-contained dataset, we explore the possibility ...
Health & Medicine Heart Disease
Rogers, John A.
See Also: Health & Medicine Heart Disease· Medical Imaging· Vioxx· Matter & Energy Electronics· Technology· Medical Technology· Reference Artificial heart· Biosensor· Circuit design· Machine· Science and stretchable electronics can map waves of electrical activity in the heart with better resolution and speed
Amyloid Deposits: Protection Against Toxic Protein Species?
Lindquist, Susan
Neurodegenerative diseases ranging from Alzheimer’s disease and polyglutamine diseases to transmissible spongiform encephalopathies are associated with the aggregation and accumulation of misfolded proteins. In several ...
Anonymous,
1979-01-01T23:59:59.000Z
new disease which causes root and stem rot to soybeans and other legumes in several southern states. The earliest sympt om is yellowing of leaves of individual plants or patches of plants across fields. Leaves of damaged plants usually develop... new soybean disease restricts root development and causes an absence of nitrogen-fixing nodules. Plants are stunted in an irregular pattern that may resemble manganese toxicity, or moisture or potash deficiency. High nematode populations often...
Ad Lucem: Modeling of Market Transformation Pathways Workshop Agenda |
Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankShale_Gas.pdfService on the TargetFY12 DOE -NAT IONA L S47.1 (June 2004) 1June|AD LUCEM ... TOWARD
Addendum Added to Innovative Demonstration of Geothermal Energy Production
Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankShale_Gas.pdfService on the TargetFY12 DOE -NAT IONA L S47.1 (June 2004) 1June|AD LUCEM
Some engineering properties of heavy concrete added silica fume
Akka?, Ay?e [Suleyman Demirel University Teknoloji Fakültesi, Isparta (Turkey); Ba?yi?it, Celalettin; Esen, Serap [Suleyman Demirel University, Mühendislik Fakültesi, Isparta (Turkey)
2013-12-16T23:59:59.000Z
Many different types of building materials have been used in building construction for years. Heavy concretes can be used as a building material for critical building as it can contain a mixture of many heavy elements. The barite itself for radiation shielding can be used and also in concrete to produce the workable concrete with a maximum density and adequate structural strength. In this study, some engineering properties like compressive strength, elasticity modules and flexure strength of heavy concretes’ added Silica fume have been investigated.
AD Hydro Power Ltd ADHPL | Open Energy Information
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousPlasmaP a g eWorks - As Prepared forChoiceNEG Micon AVestasInformation 2-MOptions in theAD Hydro Power Ltd
Value Added Energy Information Systems VAEIS | Open Energy Information
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousPlasmaP a g eWorks -09-0018-CXNuonYuchengRichlands,projectUrat Rear BannerUtilityVANEValue Added Energy
An Experiment with Digital Lighting in Adding Machine: A Musical
Esfandiary, Rana; Reaney, Mark
2014-01-01T23:59:59.000Z
of house position. Virtual scenic elements were Figure 1. Mr. Zero at the office. Note the animation clip of swirling numbers visible on the stage floor. by Rana Esfandiary and Mark Reaney an experiment with digital l ighting in Adding Machine: A... in this production was two pair of computers and digital projectors, one mounted house left, the other house right, from which lighting effects could be gener- ated in real time using a series of recorded video sequences and real-time video manipulation software...
Generalized Parton Distributions for the Proton in AdS/QCD
Chakrabarti, Dipankar
2013-01-01T23:59:59.000Z
We present a study of proton GPDs in both momentum and position spaces using proton wavefunction obtained from AdS/ QCD. Here we consider the soft wall model. The results are compared with a phenomenological model of proton GPDs.
TDROP: A routing protocol for physically hierarchical ad hoc mobile networks
Ahmed, Zaheer
2000-01-01T23:59:59.000Z
Many protocols for routing in mobile ad hoc networks have been proposed. None of these protocols differentiates mobile nodes based on their physical characteristics and also there is only one proposal for connecting ad hoc networks together to form...
Comparison of value-added models for school ranking and classification: a Monte Carlo study
Wang, Zhongmiao
2009-05-15T23:59:59.000Z
A “Value-Added” definition of school effectiveness calls for the evaluation of schools based on the unique contribution of schools to individual student academic growth. The estimates of value-added school effectiveness are usually used for ranking...
TDROP: A routing protocol for physically hierarchical ad hoc mobile networks
Ahmed, Zaheer
2000-01-01T23:59:59.000Z
Many protocols for routing in mobile ad hoc networks have been proposed. None of these protocols differentiates mobile nodes based on their physical characteristics and also there is only one proposal for connecting ad hoc ...
Service Discovery in Mobile Ad Hoc Networks: A Field Theoretic Approach Vincent Lenders
Lenders, Vincent
Service Discovery in Mobile Ad Hoc Networks: A Field Theoretic Approach Vincent Lenders , Martin: {lenders, may, plattner}@tik.ee.ethz.ch Abstract Service discovery in mobile ad hoc networks is challeng
Spatial Interference Mitigation for Multiple Input Multiple Output Ad Hoc Networks: MISO Gains
Paris-Sud XI, Université de
Spatial Interference Mitigation for Multiple Input Multiple Output Ad Hoc Networks: MISO Gains beamforming for a multiple input single output (MISO) ad hoc network to increase the density of successful
Digital ad morphing : using behavioral analysis to increase response rates to online advertisements
Link, Cordelia S
2011-01-01T23:59:59.000Z
This paper details the implementation and testing of a digital ad morphing system, a system which determines user cognitive style based on interaction with a website and serves ads designed to complement that cognitive ...
Jenkins, Marisa Rachael
2009-01-01T23:59:59.000Z
Automatic Dependent Surveillance-Broadcast (ADS-B) is considered to be a crucial part of the next generation of air transportation systems worldwide. Developing mature ADS-B applications which provide stakeholders with ...
Matching the Hagedorn temperature in AdS/CFT correspondence
Harmark, Troels; Orselli, Marta [Niels Bohr Institute and Nordita Blegdamsvej 17, 2100 Copenhagen O (Denmark)
2006-12-15T23:59:59.000Z
We match the Hagedorn/deconfinement temperature of planar N=4 super Yang-Mills (SYM) on RxS{sup 3} to the Hagedorn temperature of string theory on AdS{sub 5}xS{sup 5}. The match is done in a near-critical region where both gauge theory and string theory are weakly coupled. The near-critical region is near a point with zero temperature and critical chemical potential. On the gauge-theory side we are taking a decoupling limit found in Ref. 7 in which the physics of planar N=4 SYM is given exactly by the ferromagnetic XXX{sub 1/2} Heisenberg spin chain. We find moreover a general relation between the Hagedorn/deconfinement temperature and the thermodynamics of the Heisenberg spin chain and we use this to compute it in two distinct regimes. On the string-theory side, we identify the dual limit for which the string tension and string coupling go to zero. This limit is taken of string theory on a maximally supersymmetric pp-wave background with a flat direction, obtained from a Penrose limit of AdS{sub 5}xS{sup 5}. We compute the Hagedorn temperature of the string theory and find agreement with the Hagedorn/deconfinement temperature computed on the gauge-theory side.
Periodontal Disease and Heart Health
Goldman, Steven A.
Periodontal Disease and Heart Health Deaf HealthTalks Presenter: Christopher Lehfeldt, DDS Elmwood #12;X-ray showing bone loss rickwilsondmd.typepad.com Thursday, March 15, 12 #12;5. What is heart disease? · The medical name for heart disease is cardiovascular disease (CVD) · An American dies from CVD
Enhancing the Security of On-demand Routing in Ad Hoc Networks
California at Santa Cruz, University of
Enhancing the Security of On-demand Routing in Ad Hoc Networks Zhenjiang Li1 and J.J. Garcia, to be truly effective, communication over such networks should be secure. The attacks to an ad hoc network can Springer-Verlag Berlin Heidelberg 2005 #12;Enhancing the Security of On-demand Routing in Ad Hoc Networks
Influences of Government Interventions on Increasing Value-Added Wood Product Exports from Ghana
Influences of Government Interventions on Increasing Value-Added Wood Product Exports from Ghana exporting raw materials such lumber to exporting processed or value-added wood products. In the mid-1990s on increasing value-added exports. These actions are: 1) the imposition of a levy on air-dried lumber exports, 2
Wireless ad hoc networks Acknowledgement: Slides borrowed from Richard Y. Yang @ Yale
Gao, Jie
are not flexible. Vulnerable to attacks. · Ad hoc networks· Ad hoc networks Flexible, easy to deploy, cheaper · Optimal power assignment /transmission range · Optimal scheduling & multi-hop routing · Node are staticWireless ad hoc networks Acknowledgement: Slides borrowed from Richard Y. Yang @ Yale #12
A Multiobjective Performance Evaluation Framework for Routing in Wireless Ad Hoc
Jaffrès-Runser, Katia
network when delay, robustness and energy are considered. I. INTRODUCTION Wireless ad hoc and sensor to transmission delay [8], energy consumption [9] or fairness [10] are added on top of its main design goalA Multiobjective Performance Evaluation Framework for Routing in Wireless Ad Hoc Networks Katia
Asplund et al. Wireless Ad Hoc Dissemination for Search and Rescue Proceedings of the 7th
Asplund et al. Wireless Ad Hoc Dissemination for Search and Rescue Proceedings of the 7th International ISCRAM Conference Seattle, USA, May 2010 1 Wireless Ad Hoc Dissemination for Search and Rescue communication and Internet connectivity. Even if we consider wireless ad hoc communication as a means
Reliable and Energy-Efficient Routing for Static Wireless Ad Hoc Networks with Unreliable Links
Wang, Yu
Reliable and Energy-Efficient Routing for Static Wireless Ad Hoc Networks with Unreliable Links. In this paper, we address the problem of energy efficient reliable routing for wireless ad hoc networks communication, energy efficiency. Ç 1 INTRODUCTION WIRELESS ad hoc networks draw lots of attentions in recent
Clique-Based Randomized Multiple Access for Energy-Efficient Wireless Ad Hoc Networks
Clique-Based Randomized Multiple Access for Energy-Efficient Wireless Ad Hoc Networks Paul G. INTRODUCTION WIRELESS sensor networks, as well as other ad-hoc sys- tems that network energy-limited nodes are often traded for energy efficiency in the latter. MAC (media access control) protocols for wireless ad
Low-complexity energy-efficient broadcasting in wireless ad-hoc networks using network coding
Chen, Yuanzhu Peter
Low-complexity energy-efficient broadcasting in wireless ad-hoc networks using network coding J energy broadcasting in ad-hoc wireless networks is NP-complete [3] and a large number of approximation of minimizing the energy per bit when multicasting in an ad-hoc wireless network. An alternative formulation
FaultTolerant Distributed Algorithms in Sparse Ad Hoc Wireless Networks
FaultTolerant Distributed Algorithms in Sparse Ad Hoc Wireless Networks (SPAWN) BETTINA WEISS communication technologies, wireless ad hoc networks are increasingly commonplace nowadays. Spontaneous (``ad wireless sensor networks and disaster area communication systems. It is also a major enabling technology
q-Deformation of the AdS5 x S5 Superstring S-matrix and its Relativistic Limit
Hoare, Ben; Miramontes, J Luis
2011-01-01T23:59:59.000Z
A set of four factorizable non-relativistic S-matrices for a multiplet of fundamental particles are defined based on the R-matrix of the quantum group deformation of the centrally extended superalgebra su(2|2). The S-matrices are a function of two independent couplings g and q=exp(i\\pi/k). The main result is to find the scalar factor, or dressing phase, which ensures that the unitarity and crossing equations are satisfied. For generic (g,k), the S-matrices are branched functions on a product of rapidity tori. In the limit k->infinity, one of them is identified with the S-matrix describing the magnon excitations on the string world sheet in AdS5 x S5, while another is the mirror S-matrix that is needed for the TBA. In the g->infinity limit, the rapidity torus degenerates, the branch points disappear and the S-matrices become meromorphic functions, as required by relativistic S-matrix theory. However, it is only the mirror S-matrix which satisfies the correct relativistic crossing equation. The mirror S-matrix ...
No-carrier-added (/sup 18/F)-N-methylspiroperidol
Shiue, C.Y.; Fowler, J.S.; Wolf, A.P.
1985-10-04T23:59:59.000Z
The present invention is directed to the synthesis of a radioligand, labeled with a positron emitting radionuclide which is suitable for dynamic studies in humans using positron emission transaxial tomography. No-carrier-added (NCA) (/sup 18/F)-N-methylspiroperiodl is prepared from four different sustrates: p-nitrobenzonitrile, cyclopropyl p-nitrophenyl ketone, p-cyclopropanoyl-N,N,N-trimethylanilinium iodide and p-cyclopropanoyl-N,N,N-trimethylanilinium perchlorate. The process for the production of NCA (/sup 18/F)-N-methylspiroperidol is a nucleophilic aromatic substitution reaction. Furthermore, the compound of this invention is shown to be effective as a new drug of choice for in vivo examination of dopamine binding sites in a human brain. In particular, this drug is primarily useful in the noninvasive technique of positron emission transaxial tomography (PETT).
AdSplit: Separating smartphone advertising from applications
Shekhar, Shashi; Wallach, Dan S
2012-01-01T23:59:59.000Z
A wide variety of smartphone applications today rely on third-party advertising services, which provide libraries that are linked into the hosting application. This situation is undesirable for both the application author and the advertiser. Advertising libraries require additional permissions, resulting in additional permission requests to users. Likewise, a malicious application could simulate the behavior of the advertising library, forging the user's interaction and effectively stealing money from the advertiser. This paper describes AdSplit, where we extended Android to allow an application and its advertising to run as separate processes, under separate user-ids, eliminating the need for applications to request permissions on behalf of their advertising libraries. We also leverage mechanisms from Quire to allow the remote server to validate the authenticity of client-side behavior. In this paper, we quantify the degree of permission bloat caused by advertising, with a study of thousands of downloaded ap...
ANTIHYDROGEN PRODUCTION AND PRECISION SPECTROSCOPY WITH ATHENA/AD-1
M. HOLZSCHEITER; C. AMSLER; ET AL
2000-11-01T23:59:59.000Z
CPT invariance is a fundamental property of quantum field theories in flat space-time. Principal consequences include the predictions that particles and their antiparticles have equal masses and lifetimes, and equal and opposite electric charges and magnetic moments. It also follows that the fine structure, hyperfine structure, and Lamb shifts of matter and antimatter bound systems should be identical. It is proposed to generate new stringent tests of CPT using precision spectroscopy on antihydrogen atoms. An experiment to produce antihydrogen at rest has been approved for running at the Antiproton Decelerator (AD) at CERN. We describe the fundamental features of this experiment and the experimental approach to the first phase of the program, the formation and identification of low energy antihydrogen.
Rethinking Information Theory for Mobile Ad Hoc Networks
Andrews, Jeff; Haenggi, Martin; Berry, Randy; Jafar, Syed; Guo, Dongning; Shakkottai, Sanjay; Heath, Robert; Neely, Michael; Weber, Steven; Yener, Aylin
2007-01-01T23:59:59.000Z
The subject of this paper is the long-standing open problem of developing a general capacity theory for wireless networks, particularly a theory capable of describing the fundamental performance limits of mobile ad hoc networks (MANETs). A MANET is a peer-to-peer network with no pre-existing infrastructure. MANETs are the most general wireless networks, with single-hop, relay, interference, mesh, and star networks comprising special cases. The lack of a MANET capacity theory has stunted the development and commercialization of many types of wireless networks, including emergency, military, sensor, and community mesh networks. Information theory, which has been vital for links and centralized networks, has not been successfully applied to decentralized wireless networks. Even if this was accomplished, for such a theory to truly characterize the limits of deployed MANETs it must overcome three key roadblocks. First, most current capacity results rely on the allowance of unbounded delay and reliability. Second, ...
Sonde Adjust Value-Added Product Technical Report
Troyan, D
2012-01-09T23:59:59.000Z
The Sonde Adjust (SONDEADJUST) value-added product (VAP) creates a file that includes all fields from original Atmospheric Radiation Measurement Climate Research Facility (ARM Facility) radiosonde files and contains several value-added fields that provide adjustments related to well-known humidity issues. SONDEADJUST produces data that correct documented biases in radiosonde humidity measurements. Previous efforts towards applying some of these corrections are available via the discontinued PI product sgpsondecorr1miloC1. Unique fields contained within this datastream include smoothed original relative humidity, dry bias corrected relative humidity, and final corrected relative humidity. The smoothed RH field refines the relative humidity from integers-the resolution of the instrument-to fractions of a percent. This profile is then used to calculate the dry bias corrected field. The final correction fixes the time-lag problem and uses the dry-bias field as input into the algorithm. In addition to dry bias, solar heating is another correction that is encompassed in the final corrected RH field. Output from SONDEADJUST differs from the previous RH-corrected datastreams in important ways. First, all three types of ARM radiosondes-Vaisala RS-80, RS-90, and RS-92-are corrected using dedicated procedures and/or parameters. Second, the output variables include all of those found in the original radiosonde file: dry bulb temperature, dewpoint temperature, wind speed, wind direction, eastward wind component, northward wind component, wind status (a Vaisala-produced field used in conjunction with the Loran system), ascent rate, and original relative humidity. Additional humidity fields are smoothed relative humidity, dry biased corrected relative humidity, final ambient relative humidity, and scaled adjusted relative humidity. Third, quality control (QC) flags of the fields from the original radiosonde datastream are brought into the SONDEADJUST output file. Additional QC variables are created for the new fields.
Mukherji, Anuradha
2001-01-01T23:59:59.000Z
in three Hindu temples built in the southern state of Tamilnadu in India. These three temple are the Shore temple built at Mahabalipuram by the Pallava dynasty (700 AD); the Brihadeshvara temple built at Tanjore by the Chola dynasty (1010 AD...
AdS/Ricci-flat correspondence and the Gregory-Laflamme instability
Marco M. Caldarelli; Joan Camps; Blaise Goutéraux; Kostas Skenderis
2013-03-20T23:59:59.000Z
We show that for every asymptotically AdS solution compactified on a torus there is a corresponding Ricci-flat solution obtained by replacing the torus by a sphere, performing a Weyl rescaling of the metric and appropriately analytically continuing the dimension of the torus/sphere (as in generalized dimensional reduction). In particular, it maps Minkowski spacetime to AdS on a torus, the holographic stress energy tensor of AdS to the stress energy tensor due to a brane localized in the interior of spacetime and AdS black branes to (asymptotically flat) Schwarzschild black branes. Applying it to the known solutions describing the hydrodynamic regime in AdS/CFT, we derive the hydrodynamic stress-tensor of asymptotically flat black branes to second order, which is constrained by the parent conformal symmetry. We compute the dispersion relation of the Gregory-Laflamme unstable modes through cubic order in the wavenumber, finding remarkable agreement with numerical data. In the case of no transverse sphere, AdS black branes are mapped to Rindler spacetime and the second-order transport coefficients of the fluid dual to Rindler spacetime are recovered.
q-Deformation of the AdS5 x S5 Superstring S-matrix and its Relativistic Limit
Ben Hoare; Timothy J. Hollowood; J. Luis Miramontes
2011-12-19T23:59:59.000Z
A set of four factorizable non-relativistic S-matrices for a multiplet of fundamental particles are defined based on the R-matrix of the quantum group deformation of the centrally extended superalgebra su(2|2). The S-matrices are a function of two independent couplings g and q=exp(i\\pi/k). The main result is to find the scalar factor, or dressing phase, which ensures that the unitarity and crossing equations are satisfied. For generic (g,k), the S-matrices are branched functions on a product of rapidity tori. In the limit k->infinity, one of them is identified with the S-matrix describing the magnon excitations on the string world sheet in AdS5 x S5, while another is the mirror S-matrix that is needed for the TBA. In the g->infinity limit, the rapidity torus degenerates, the branch points disappear and the S-matrices become meromorphic functions, as required by relativistic S-matrix theory. However, it is only the mirror S-matrix which satisfies the correct relativistic crossing equation. The mirror S-matrix in the relativistic limit is then closely related to that of the semi-symmetric space sine-Gordon theory obtained from the string theory by the Pohlmeyer reduction, but has anti-symmetric rather than symmetric bound states. The interpolating S-matrix realizes at the quantum level the fact that at the classical level the two theories correspond to different limits of a one-parameter family of symplectic structures of the same integrable system.
Lapshina, Elena V. (Troitsk, RU); Zhuikov, Boris L. (Troitsk, RU); Srivastava, Suresh C. (Setauket, NY); Ermolaev, Stanislav V. (Obninsk, RU); Togaeva, Natalia R. (Obninsk, RU)
2012-01-17T23:59:59.000Z
The invention provides a method of chemical recovery of no-carrier-added radioactive tin (NCA radiotin) from intermetallide TiSb irradiated with accelerated charged particles. An irradiated sample of TiSb can be dissolved in acidic solutions. Antimony can be removed from the solution by extraction with dibutyl ether. Titanium in the form of peroxide can be separated from tin using chromatography on strong anion-exchange resin. In another embodiment NCA radiotin can be separated from iodide solution containing titanium by extraction with benzene, toluene or chloroform. NCA radiotin can be finally purified from the remaining antimony and other impurities using chromatography on silica gel. NCA tin-117m can be obtained from this process. NCA tin-117m can be used for labeling organic compounds and biological objects to be applied in medicine for imaging and therapy of various diseases.
Reproductive Diseases in Cattle
Sprott, L. R.; Field, Bob
1998-12-03T23:59:59.000Z
susceptible. Droplets of urine from infected cows can infect normal cows after contact with the eye or mucous membranes of the nose or mouth. The disease infects more cattle each day, preventing cows from settling and lengthening their calving intervals... abortus) fetal membranes from aborting heifers at 4-12 not vaccinate bulls. cow; fetus; months. placenta Leptospirosis Bacterial (At least Urine of infected Any stage, Sample 10 Every 6 months Laboratory should deter- 5 serotypes) animals...
Horne, Wendell C.
1974-01-01T23:59:59.000Z
Acknowledgments This publication was made possible by a grant from the Texas Peanut Producers Board to the Texas Agricultural Extension Service. This educational support in the area of peanut disease control is appreciated. The author also expresses... appreciation to producers who contributed through the voluntary check-off program and to those Extension staff members and research plant pathologists and nematologists who gave assistance and counsel during the prepara tion of this publication . Peanut...
No-carrier-added (18F)-N-methylspiroperidol
Shiue, Chyng-Yann; Fowler, Joanna S.; Wolf, Alfred P.
1993-07-06T23:59:59.000Z
There is disclosed a radioligand labeled with a positron emitting radionuclide suitable for dynamic study in living humans with positron emission transaxial tomography. [.sup.18 F]-N-methylspiroperidol, exhibiting extremely high affinity for the dopamine receptors, provides enhanced uptake and retention in the brain concomitant with reduced radiation burden. These characteristics all combine to provide [.sup.18 F]-N-methylspiroperidol as a radioligand superior to known radioligands for mapping dopamine receptors in normal and disease states in the living brain. Additionally, a new synthetic procedure for this material is disclosed.
No-carrier-added (18F)-N-methylspiroperidol
Shiue, Chyng-Yann (East Setauket, NY); Fowler, Joanna S. (Bellport, NY); Wolf, Alfred P. (Setauket, NY)
1993-01-01T23:59:59.000Z
There is disclosed a radioligand labeled with a positron emitting radionuclide suitable for dynamic study in living humans with positron emission transaxial tomography. [.sup.18 F]-N-methylspiroperidol, exhibiting extremely high affinity for the dopamine receptors, provides enhanced uptake and retention in the brain concomitant with reduced radiation burden. These characteristics all combine to provide [.sup.18 F]-N-methylspiroperidol as a radioligand superior to known radioligands for mapping dopamine receptors in normal and disease states in the living brain. Additionally, a new synthetic procedure for this material is disclosed.
Hall, C. F.; Bell, R. R.; Clifford, R. L., Jr.; Glass, S. E.; Grimes, J. E.; Grumbles, L. C.; Keahey, E. E.; Wormell, B. C.
1971-01-01T23:59:59.000Z
Foreign animal disease can cause serious damage to the United States (US) agricultural sector and foot-and-mouth disease (FMD), in particular, poses a serious threat. FMD causes death and reduced fecundity in infected ...
Inherited risk for common disease
Banava, Helen
2007-01-01T23:59:59.000Z
Linkage disequilibrium studies have discovered few gene-disease associations for common diseases. The explanation has been offered that complex modes of inheritance govern risk for cancers, cardiovascular and cerebrovascular ...
Scanning Tunneling Macroscopy, Black Holes, and AdS/CFT Bulk Locality
Soo-Jong Rey; Vladimir Rosenhaus
2014-06-02T23:59:59.000Z
We establish resolution bounds on reconstructing a bulk field from boundary data on a timelike hypersurface. If the bulk only supports propagating modes, reconstruction is complete. If the bulk also supports evanescent modes, local reconstruction is not achievable unless one has exponential precision in knowledge of the boundary data. Without exponential precision, for a Minkowski bulk, one can reconstruct a spatially coarse-grained bulk field, but only out to a depth set by the coarse-graining scale. For an asymptotically AdS bulk, reconstruction is limited to a spatial coarse-graining proper distance set by the AdS scale. AdS black holes admit evanescent modes. We study the resolution bound in the large AdS black hole background and provide a dual CFT interpretation. Our results demonstrate that, if there is a black hole of any size in the bulk, then sub-AdS bulk locality is no longer well-encoded in boundary data in terms of local CFT operators. Specifically, in order to probe the bulk on sub-AdS scales using only boundary data in terms of local operators, one must either have such data to exponential precision or make further assumptions about the bulk state.
Can adding oil control domain formation in binary amphiphile bilayers?
M. J. Greenall; C. M. Marques
2014-06-12T23:59:59.000Z
Bilayers formed of two species of amphiphile of different chain lengths may segregate into thinner and thicker domains composed predominantly of the respective species. Using a coarse-grained mean-field model, we investigate how mixing oil with the amphiphiles affects the structure and thickness of the bilayer at and on either side of the boundary between two neighbouring domains. In particular, we find that oil molecules whose chain length is close to that of the shorter amphiphiles segregate to the thicker domain. This smooths the surface of the hydrophobic bilayer core on this side of the boundary, reducing its area and curvature and their associated free-energy penalties. The smoothing effect is weaker for oil molecules that are shorter or longer than this optimum value: short molecules spread evenly through the bilayer, while long molecules swell the thicker domain, increasing the surface area and curvature of the bilayer core in the interfacial region. Our results show that adding an appropriate oil could make the formation of domain boundaries more or less favourable, raising the possibility of controlling the domain size distribution.
Cloud Condensation Nuclei Profile Value-Added Product
McFarlane, S; Sivaraman, C; Ghan, S
2012-10-08T23:59:59.000Z
The cloud condensation nuclei (CCN) concentration at cloud base is the most relevant measure of the aerosol that influences droplet formation in clouds. Since the CCN concentration depends on supersaturation, a more general measure of the CCN concentration is the CCN spectrum (values at multiple supersaturations). The CCN spectrum is now measured at the surface at several fixed ARM sites and by the ARM Mobile Facility (AMF), but is not measured at the cloud base. Rather than rely on expensive aircraft measurements for all studies of aerosol effects on clouds, a way to project CCN measurements at the surface to cloud base is needed. Remote sensing of aerosol extinction provides information about the vertical profile of the aerosol, but cannot be directly related to the CCN concentration because the aerosol extinction is strongly influenced by humidification, particularly near cloud base. Ghan and Collins (2004) and Ghan et al. (2006) propose a method to remove the influence of humidification from the extinction profiles and tie the “dry extinction” retrieval to the surface CCN concentration, thus estimating the CCN profile. This methodology has been implemented as the CCN Profile (CCNPROF) value-added product (VAP).
Adding Priorities to Total Order Broadcast Protocols Emili Miedes, Francesc D. Mu~noz-Escoi
Muñoz, Francesc
Adding Priorities to Total Order Broadcast Protocols Emili Miedes, Francesc D. Mu~noz-Esco,fmunyoz}@iti.upv.es Technical Report TR-ITI-ITE-07/23 (supersedes TR-ITI-ITE-07/07) E.Miedes,F.D.Mu~noz-Esco´i:AddingPrioritiestoTotalOrderBroadcastProtocolsTR-ITI-ITE-07/23( #12;#12;Adding Priorities to Total Order Broadcast Protocols Emili Miedes, Francesc D. Mu~noz-Esco
Singh, Santosh Kumar
2010-01-01T23:59:59.000Z
Spectrum is a scarce commodity, and considering the spectrum scarcity faced by the wireless-based service providers led to high congestion levels. Technical inefficiencies from pooled spectrum (this is nothing but the "common carrier principle" adopted in oil/gas/electricity pipelines/networks.), since all ad hoc networks share a common pool of channels, exhausting the available channels will force ad hoc networks to block the services. Researchers found that cognitive radio (CR) technology may resolve the spectrum scarcity. CR network proved to next generation wireless communication system that proposed as a way to reuse under-utilised spectrum of licensee user (primary network) in an opportunistic and non-interfering basis. A CR is a self-configuring entity in a wireless networking that senses its environment, tracks changes, and frequently exchanges information with their networks. Adding this layer of such intelligence to the ad hoc network by looking at the overall geography of the network known as cogni...
ADDING VALUE TO ARM PRECIPITATION RADAR MEASUREMENTS Scott Collis, Argonne National Laboratory
ADDING VALUE TO ARM PRECIPITATION RADAR MEASUREMENTS Scott Collis, Argonne National Laboratory over the ARM sites. A particular focus will be on parameters highlighted in recent white papers
Top Value-Added Chemicals from Biomass - Volume II?Results of...
Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site
Screening for Potential Candidates from Biorefinery Lignin Top Value-Added Chemicals from Biomass - Volume IIResults of Screening for Potential Candidates from Biorefinery Lignin...
Top Value Added Chemicals from Biomass: Volume I--Results of...
Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site
Volume I--Results of Screening for Potential Candidates from Sugars and Synthesis Gas Top Value Added Chemicals from Biomass: Volume I--Results of Screening for Potential...
No-carrier-added [.sup.18 F]-N-fluoroalkylspiroperidols
Shiue, Chyng-Yann (East Setauket, NY); Wolf, Alfred P. (Setauket, NY); Bai, Lan-Qin (Upton, NY); Teng, Ren-Tui (Upton, NY)
1989-01-01T23:59:59.000Z
There is disclosed radioligands labeled with the position emitting radionuclide [.sup.18 F] suitable for dynamic study in living humans with position emission transaxial tomography. These new [.sup.18 F]-N-fluoroalkylspiroperidols, wherein the alkyl group contains from 2-6 carbon atoms, exhibit extremely high affinity for the dopamine receptors and provide enhanced uptake and retention in the brain concomitant with reduced radiation burden. These characteristics all combine to make these new radioligands useful for mapping dopamine receptors in normal and disease states in the living brain. Additionally, a new synthetic procedure for these radioligands as well as a new procedure for preparing the radiolabeled alkyl halide alkylating reagents are also disclosed.
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
Fernando, Sudarshan; Günaydin, Murat
2015-01-01T23:59:59.000Z
We study the minimal unitary representation (minrep) of SO(5, 2), obtained by quantization of its geometric quasiconformal action, its deformations and supersymmetric extensions. The minrep of SO(5, 2) describes a massless conformal scalar field in five dimensions and admits a unique “deformation” which describes a massless conformal spinor. Scalar and spinor minreps of SO(5, 2) are the 5d analogs of Dirac’s singletons of SO(3, 2). We then construct the minimal unitary representation of the unique 5d supercon-formal algebra F(4) with the even subalgebra SO(5, 2) ×SU(2). The minrep of F(4) describes a massless conformal supermultiplet consisting of two scalar andmore »one spinor fields. We then extend our results to the construction of higher spin AdS6/CFT5 (super)-algebras. The Joseph ideal of the minrep of SO(5, 2) vanishes identically as operators and hence its enveloping algebra yields the AdS6/CFT5 bosonic higher spin algebra directly. The enveloping algebra of the spinor minrep defines a “deformed” higher spin algebra for which a deformed Joseph ideal vanishes identically as operators. These results are then extended to the construction of the unique higher spin AdS6/CFT5 superalgebra as the enveloping algebra of the minimal unitary realization of F(4) obtained by the quasiconformal methods.« less
, natural history study that included three university- based AD centers in the United States. A total of 201 patients diagnosed with probable AD with mod- ified Mini-Mental State Examination (MMSE) scores assessment, and time to cognitive (MMSE score 10) and functional (Blessed Dementia Rating Scale score 10
Development of Graves' disease following radiation therapy in Hodgkin's disease
Loeffler, J.S.; Tarbell, N.J.; Garber, J.R.; Mauch, P.
1988-01-01T23:59:59.000Z
Radiation-related thyroid dysfunction is a common occurrence in patients with Hodgkin's disease treated with mantle field radiation. Although chemical and clinical hypothyroidism are most commonly seen, Graves' disease has also been described. We have examined the records of 437 surgically staged patients who received mantle field irradiation between April 1969 and December 1980 to ascertain the frequency of manifestations of Graves' disease. Within this group, seven patients developed hyperthyroidism accompanied by ophthalmic findings typical of those seen in Graves' disease. The actuarial risk of developing Graves' disease at 10 years following mantle irradiation for Hodgkin's disease was 3.3% in female patients and 1% in male patients in this study. The observed/expected ratios were 5.9 and 5.1 for female and male patients, respectively. This observed risk significantly exceeded that seen in the general population.
Charette, André
2014 PROGRAM TO ACCELERATE CLINICAL TRIALS (PACT) RFP The true test for new Alzheimer's drugs of these potentially successful drugs have not been brought to human trials because of the increased cost and risk Trials (PACT). The goal of this Request for Proposals (RFP) is to increase the number of innovative drugs
Interes'ng-Phrase Mining for Ad-Hoc Text Analy'cs
Interes'ng-Phrase Mining for Ad-Hoc Text Analy'cs Klaus Berberich (kberberi Weikum (originally presented at VLDB 2010) #12;Interes'ng-Phrase Mining for Ad-Hoc Text.g., iden'fy characteris'c quota'ons by barack obama) 2 / 27 #12;Interes'ng-Phrase Mining
Prediction of Advertiser Churn for Google AdWords Sangho Yoon Jim Koehler Adam Ghobarah
Cortes, Corinna
Prediction of Advertiser Churn for Google AdWords Sangho Yoon Jim Koehler Adam Ghobarah AbstractWords. In this work, we first propose a new definition of advertiser churn for AdWords advertisers; second we present advertiser churn; and third we build a model to predict advertiser churn using machine learning algorithms
Design techniques for low noise and high speed A/D converters
Gupta, Amit Kumar
2009-05-15T23:59:59.000Z
. The resolution and sampling rate of an A/D converter vary depending on the application. Recently, there has been a growing demand for broadband (>1 MHz), high-resolution (>14bits) A/D converters. Applications that demand such converters include asymmetric digital...
On the Effectiveness of Monitoring for Intrusion Detection in Mobile Ad Hoc Networks
Chen, Ing-Ray
to that of the experimental testbed. Simulations of larger (50-node) ad hoc networks indicate that monitoring-based intrusion evaluations of IDTs are based on small testbed configura- tions, or simulations which do not incorporate any on monitoring- based intrusion detection for ad hoc networks. Experimental results show that, even for a simple
Securing Ad Hoc Wireless Networks Against Data Injection Attacks Using Firewalls
Kasera, Sneha Kumar
Securing Ad Hoc Wireless Networks Against Data Injection Attacks Using Firewalls Jun Cheol Park-- We propose to secure ad hoc networks against data injection attacks by placing firewall functionality] simulations. Our results show that our algorithm can find near-optimal solutions. Based on a simple analysis
Fuzzy Trust Recommendation Based on Collaborative Filtering for Mobile Ad-hoc Networks
Zhang, Yi
Fuzzy Trust Recommendation Based on Collaborative Filtering for Mobile Ad-hoc Networks Junhai Luo1--Mobile ad-hoc networks (MANETs) are based on the cooperative and trust characteristic of the mobile nodes focused on building up trust among distributed network nodes to simulate cooperation and improving
A Trust-based Architecture for Managing Certificates in Vehicular Ad hoc Networks
Paris-Sud XI, Université de
propose a secure and distributed public key infrastructure for vehicular ad hoc networks VANETs basedA Trust-based Architecture for Managing Certificates in Vehicular Ad hoc Networks Tahani Gazdar authority CA. We conducted a set of simulations in which we evaluate the efficiency and the stability
Preventing Wormhole Attacks on Wireless Ad Hoc Networks: A Graph Theoretic Approach
Lazos, Loukas
then propose a Local Broad- cast Key (LBK) based method to secure an ad hoc network from wormhole attacks simulation results to illustrate our theory. Index Terms-- wormhole, security, vulnerability, ad hoc net a decentralized realization for LBK establishment, and provide an analytical evaluation of the security level
EAGR: Energy Aware Greedy Routing Scheme for Wireless Ad hoc Networks Sachin Sharma
Dharmaraja, S.
EAGR: Energy Aware Greedy Routing Scheme for Wireless Ad hoc Networks Sachin Sharma Tejas Networks, throughput and energy consumption. Keywords: Rate of Energy Consumption, Greedy Routing, Wireless Ad hoc distributed nodes that communicate over a wireless link. In this paper we present a scalable, Energy Aware
Name Service in IPv6 Mobile Ad-hoc Network connected to the Internet
Jeong, Jaehoon "Paul"
Name Service in IPv6 Mobile Ad-hoc Network connected to the Internet Jaehoon Jeong, Jungsoo Park-hoc network connected to the Internet. The DNS resolution of DNS names of mobile nodes within mobile ad-hoc network is performed by multicast DNS and that of DNS names of nodes in the Internet is performed through
Degree Distribution and Hopcount in Wireless Ad-hoc Networks R. Hekmat, P. Van Mieghem
Van Mieghem, Piet
Degree Distribution and Hopcount in Wireless Ad-hoc Networks R. Hekmat, P. Van Mieghem Delft focus in this article is on the degree distribution and hopcount in these networks. The results that the degree distribution in wireless ad-hoc networks is binomial for low values of the mean degree. Further
Adding STARFire Analysis Layers to Google Earth through a KML Network Link 1) Launch Google Earth
Adding STARFire Analysis Layers to Google Earth through a KML Network Link 1) Launch Google Earth 2) The network link will be added in the Places control within Google Earth. Select the node level in the tree layers for viewing within Google Earth. Double clicking on a layer will zoom you to the extent
DELAR: Device/Energy/Load Aware Relaying in Heterogenous Wireless Ad Hoc Networks
Zhang, Yanchao
- newable energy sources. In DELAR the heterogeneity of nodal energy capabilities or device types, nodalDELAR: Device/Energy/Load Aware Relaying in Heterogenous Wireless Ad Hoc Networks Wei Liu Energy conservation is of great importance for mobile ad hoc networks in which most nodes are equipped
A SERVICE DISCOVERY THREAT MODEL FOR AD HOC Adrian Leung and Chris Mitchell
Mitchell, Chris
A SERVICE DISCOVERY THREAT MODEL FOR AD HOC NETWORKS Adrian Leung and Chris Mitchell Information.Leung,C.Mitchell}@rhul.ac.uk Keywords: Security, Secure Service Discovery, Threat Model, Mobile Ad Hoc Networks, MANETs. Abstract. Securing the process of service discovery is one of them. Novel solutions are therefore required. However
Coverage Problems in Wireless Ad-hoc Sensor Networks Seapahn Meguerdichian1
technology interfacing with emerging micro-sensor based on MEMs technology [2], is allowing sophisticatedCoverage Problems in Wireless Ad-hoc Sensor Networks Seapahn Meguerdichian1 , Farinaz Koushanfar2}@cs.ucla.edu {farinaz, mbs}@ee.ucla.edu Abstract - Wireless ad-hoc sensor networks have recently emerged as a premier
MobiSN: Semantics-based Mobile Ad Hoc Social Network Framework
Li, Juan "Jen"
MobiSN: Semantics-based Mobile Ad Hoc Social Network Framework Juan Li Department of Computer.khan@ndsu.edu Abstract--Mobile ad hoc social networks are self-configuring social networks that connect users using mobile devices, such as laptops, PDAs, and cellular phones. These social networks facilitate users
The Effect of Ad Rank on the Performance of Keyword Advertising Campaigns
Jansen, James
The Effect of Ad Rank on the Performance of Keyword Advertising Campaigns Bernard J. Jansen and Zhe on the performance of keyword advertising cam- paigns. We examined a large-scale data file comprised of nearly 7 tests to examine the effect of ad rank on critical keyword advertising metrics, including clicks, cost
How Do Patents Shape Global Value Chains? International and Domestic Patenting and Value-Added Trade
Sekhon, Jasjeet S.
-Added Trade October 2014 Preliminary Draft Please do not cite Nikolas J. Zolas, Center for Economic Studies that links patents to industry and trade classifications to characterize how patents affect the structure of value-added trade, we test how domestic and international (bilateral) patenting specifically related
A Series of Tubes: Adding Interactivity to 3D Prints Using Internal Pipes
Zakhor, Avideh
A Series of Tubes: Adding Interactivity to 3D Prints Using Internal Pipes Valkyrie Savage valkyrie flexibility and potential. Author Keywords Fabrication; 3D Printing; Interactive Objects; Design Tools ACM. Recently, human-computer interaction researchers have be- gun to explore adding interaction to 3D printed
Inducing Spatial Clustering in MAC Contention for Spread Spectrum Ad Hoc Networks
de Veciana, Gustavo
. Our premise is that such networks are well suited to meet quality of service and energy efficiency promise towards achieving high spatial reuse, QoS, and energy efficiency in spread spectrum ad hoc goals. At least two other objectives are critical in some ad hoc network applications: energy efficiency
Report of the Ad Hoc Committee on Washington Natural Resource Agency Reform
Borenstein, Elhanan
Report of the Ad Hoc Committee on Washington Natural Resource Agency Reform February 16, 2010 of the Environment (CoEnv) to make useful contributions to the Governor's natural resource agency reform initiative. As a result, the Washington Natural Resource Agency Reform ad hoc Committee was established and given
Energy Efficient Adaptation of Multicast Protocols in Power Controlled Wireless Ad Hoc Networks
Prasanna, Viktor K.
on energy efficiency in ad hoc networks. In this paper, we assume a more practical model for power controlEnergy Efficient Adaptation of Multicast Protocols in Power Controlled Wireless Ad Hoc Networks to power controlled networks is presented. Wireless nodes are assumed to have transmis- sion power control
Development of a PF Fired High Efficiency Power Plant (AD700)
Development of a PF Fired High Efficiency Power Plant (AD700) Rudolph Blum, Sven Kjær and Jørgen and a sea-water-cooled 800 MW AD700 power plant to start commercial operation around 2020 might reach a net emission power plant. 1 Introduction Coal reserves are significantly more abundant and much more widely
Low-Cost Truthful Multicast in Selfish and Rational Wireless Ad Hoc Networks
Li, Xiang-Yang
en- joy a more flexible composition. A wireless ad hoc network is a collection of radio devices limited transmission power. One of the dis- tinctive features of wireless networks is that the signal sent1 Low-Cost Truthful Multicast in Selfish and Rational Wireless Ad Hoc Networks Weizhao Wang Xiang
Paris-Sud XI, Université de
for petrologic sulfur estimates Fidel Costa1 and Bruno Scaillet Institut des Sciences de la Terre d'Orle´ans, UMR petrological, analytical, and thermodyna- mical data to constrain the sulfur yield of the AD 1600 Huaynaputina loading of the AD 1600 Huaynaputina eruption and implications for petrologic sulfur estimates, Geophys
The secret symmetries of the AdS/CFT reflection matrices
Vidas Regelskis
2011-08-27T23:59:59.000Z
We find new twisted Yangian symmetries of the AdS/CFT reflection matrices for the Y=0 maximal giant graviton and D5-brane. These new symmetries originate from the known secret symmetries of the Yangian symmetry of the AdS/CFT S-matrix.
A Cross-Layer Framework for Exploiting Virtual MISO Links in Mobile Ad Hoc Networks
Krishnamurthy, Srikanth
A Cross-Layer Framework for Exploiting Virtual MISO Links in Mobile Ad Hoc Networks Gentian requiring the deployment of physical antenna arrays. Virtual MISO entails the simultaneous transmission. We present a novel multilayer approach for exploiting virtual MISO links in ad hoc networks
Progressive Network Coding for Message-Forwarding in Ad-Hoc Wireless Networks
Chen, Yuanzhu Peter
. This paper considers the multi-hop transmission prob- lem in wireless ad-hoc networks. In a three-node sce of multi- hop transmission. The new framework, exploiting the technology of progressive network codingProgressive Network Coding for Message-Forwarding in Ad-Hoc Wireless Networks Xingkai Bao and Jing
Joint Routing and Server Selection for Multiple Description Video Streaming in Ad Hoc Networks
Hou, Y. Thomas
Joint Routing and Server Selection for Multiple Description Video Streaming in Ad Hoc Networks ad hoc networks. In this paper, we study the important problem of joint routing and server selection by the proposed approach over existing server selection schemes. This justifies the importance of jointly
Comparative Study of Price-based Resource Allocation Algorithms for Ad Hoc Networks
be an ample alterna- tive. 1. Introduction Mobile ad hoc networks are formed by wireless nodes that move freely and have no fixed infrastructure. Each node in the network may act as a router for other nodes a serious threat to critical infrastructures of the future. Due to the nature of ad hoc wireless networks
Comparison of two wireless ad hoc routing protocols on a hardware test-bed
Brown, Timothy X.
Comparison of two wireless ad hoc routing protocols on a hardware test-bed Shweta Bhandare of the rout- ing protocols is carried out using the Click modular router infrastructure on laptops with wireless ethernet cards running Linux. We demonstrate the working of both ad hoc routing protocols through
SQL is Dead; Long Live SQL: Lightweight Query Services for Ad Hoc Research Data
Matrajt, Graciela
SQL is Dead; Long Live SQL: Lightweight Query Services for Ad Hoc Research Data Bill Howe billhowe with ad hoc scientific Q&A. Further: · We reject the conventional wisdom that "scientists won't write SQL a production-quality database server. · We observe that simply sharing examples of SQL queries allows
Does Cognition Come at a Net Energy Cost in Ad Hoc Wireless LANs?
Namboodiri, Vinod
1 Does Cognition Come at a Net Energy Cost in Ad Hoc Wireless LANs? Anm Badruddoza, Vinod that are energy constrained. This work takes a first step in this direction for the ad hoc Wireless LAN scenario the importance of energy consumption in the devices that employ such techniques. Scanning for wireless spectrum
Distributed Topology Control for Power Efficient Operation in Multihop Wireless Ad Hoc Networks
of a wireless network that is operating on battery power is limited by the capacity of its energy sourceDistributed Topology Control for Power Efficient Operation in Multihop Wireless Ad Hoc Networks of wireless multihop ad hoc net- works can be controlled by varying the transmission power of each node. We
On the Energy Efficiency of Cognitive Radios -A Study of the Ad Hoc Wireless LAN Scenario
Namboodiri, Vinod
On the Energy Efficiency of Cognitive Radios - A Study of the Ad Hoc Wireless LAN Scenario Anm can save energy over a conventional radio in the Ad Hoc Wireless LAN scenario. The interplay between wireless spectrum, has however, resulted in researchers overlooking the importance of energy consumption
Energy Conserving Routing in Wireless Ad-hoc Networks Jae-Hwan Chang and Leandros Tassiulas
Wang, Bing
Energy Conserving Routing in Wireless Ad-hoc Networks Jae-Hwan Chang and Leandros Tassiulas-- energy-sensitive routing, wireless ad-hoc networks, sensor networks I. INTRODUCTION CONSIDER a group of wireless static nodes is considered as it arises in a rapidly deployed, sensor based, monitoring system
Minimizing Energy and Maximizing Network Lifetime Multicasting in Wireless Ad Hoc Networks
Liang, Weifa
Minimizing Energy and Maximizing Network Lifetime Multicasting in Wireless Ad Hoc Networks Weifa Abstract-- Most mobile nodes in a wireless ad hoc network are powered by energy limited batteries, the limited battery lifetime imposes a constraint on the network performance. Therefore, energy efficiency
ADHOC MAC: a new, flexible and reliable MAC architecture for ad-hoc networks
Borgonovo, Flaminio
ADHOC MAC: a new, flexible and reliable MAC architecture for ad-hoc networks F. Borgonovo, A, make the design of a prompt, efficient, flexible, and reliable MAC very difficult. An ad hoc network.e., transmissions that reach all terminals within the range allowed by the transmitting power. Due to radio range
LE MATERIE PRIME RINNOVABILI E LA TRANSIZIONE DA ECONOMIA DI PRODOTTO AD ECONOMIA DI SISTEMA
Genova, Università degli Studi di
LE MATERIE PRIME RINNOVABILI E LA TRANSIZIONE DA ECONOMIA DI PRODOTTO AD ECONOMIA DI SISTEMA Per aumentando la qualità della vita dei suoi abitanti. Si tratta di favorire la transizione da un'economia di prodotto ad una economia di sistema, un salto culturale verso una sostenibilità economica ed ambientale che
Using Traffic Flow for Cluster Formation in Vehicular Ad-hoc Networks
Weigle, Michele
Using Traffic Flow for Cluster Formation in Vehicular Ad-hoc Networks Mohammad S. Almalag of the traffic will flow. I. INTRODUCTION Vehicular Ad Hoc Networks (VANETs) are considered to be a class MANETs. Nodes in VANETs have more processing power and storage space and typically have no battery
High resolution A/D conversion based on piecewise conversion at lower resolution
Terwilliger, Steve (Albuquerque, NM)
2012-06-05T23:59:59.000Z
Piecewise conversion of an analog input signal is performed utilizing a plurality of relatively lower bit resolution A/D conversions. The results of this piecewise conversion are interpreted to achieve a relatively higher bit resolution A/D conversion without sampling frequency penalty.
Energy-Efficiency of Cooperative Sensing Schemes in Ad hoc WLAN Cognitive Radios
Namboodiri, Vinod
Energy-Efficiency of Cooperative Sensing Schemes in Ad hoc WLAN Cognitive Radios Reshma Syeda, we study and analyse the energy efficiency of two generic cooperative sensing schemes in an ad hoc a comparative numerical analysis to demonstrate the amount of energy savings of the proposed cooperative schemes
Design techniques for low noise and high speed A/D converters
Gupta, Amit Kumar
2009-05-15T23:59:59.000Z
. The resolution and sampling rate of an A/D converter vary depending on the application. Recently, there has been a growing demand for broadband (>1 MHz), high-resolution (>14bits) A/D converters. Applications that demand such converters include asymmetric digital...
On the Connectivity in One-Dimensional Ad Hoc Wireless Networks with a Forbidden Zone
On the Connectivity in One-Dimensional Ad Hoc Wireless Networks with a Forbidden Zone Xiaodong Hu1 This paper investigates the connectivity in one-dimensional ad hoc wireless networks with a forbidden zone. We derive the probability of the wireless networks which are composed of exactly m clusters by means
The Economic Implications of Adding Wind Capacity to a Bulk Power Transmission Network
The Economic Implications of Adding Wind Capacity to a Bulk Power Transmission Network by Tim Mount. * Corresponding author, tdm2@cornell.edu. #12;2 The Economic Implications of Adding Wind Capacity to a Bulk Power limitations of solving large AC Optimal Power Flows (OPF) for real networks, system operators typically use
SANS: A Simple Ad Hoc Network Simulator Nicolas Burri, Roger Wattenhofer, Yves Weber, Aaron present a Simple Ad Hoc Network Simulator SANS particularly intended for the simulation of distributed the concepts and correct usage of SANS as a development, debugging, testing and presentation tool. Together
1 ADS1210, 1211 24-Bit ANALOG-TO-DIGITAL CONVERTER
Hochmuth, Olaff
of 23 bits is achieved through the use of a very low-noise input amplifier at conversion rates up to 10 by provid- ing a low-noise programmable gain amplifier with a gain range of 1 to 16 in binary steps. The ADS1210 and ADS1211 are designed for high resolution measurement applications in smart trans- mitters
Cross-Layer Design for Energy-Efficient Secure Multicast Communications in Ad Hoc Networks
Poovendran, Radha
Cross-Layer Design for Energy-Efficient Secure Multicast Communications in Ad Hoc Networks Loukas, University of Washington, Seattle, WA Abstract-- We consider the problem of secure multicast in an energy network operation in an wireless ad hoc environment. Energy is a physical layer parameter, while security
Greeley, Ralph Gordon
1966-01-01T23:59:59.000Z
treatment has been discovered and the etiology of the disease has never been proven. In South Africa a similar disease, larnsiekte, has been recorded for centuries. In the 1920's intensive research in that country un- covered a chain of conditions... the similarity of lamsiekte and loin disease, and of the phosphorus deficiency that soils of South Africa and the Texas coastal plains have in common. In 1924 he began recommending the routine supplemental feeding of phos- phorus to range cattle (8). Where...
Yao, Jun; Du, Heng; Yan, Shiqiang; Fang, Fang; Wang, Chaodong; Lue, Lih-Fen; Guo, Lan; Chen, Doris; Stern, David M.; Moore, Frank J. Gunn; Chen, John Xi; Arancio, Ottavio; Yan, Shirley ShiDu
2011-02-09T23:59:59.000Z
that inhibition of the ABAD-A? interaction, using a decoy peptide (DP) in vitro and in vivo, protects against aberrant mitochondrial and neuronal function and improves spatial learning/memory. Intraperitoneal administration of ABAD-DP [fused to the transduction...