National Library of Energy BETA

Sample records for a1 a8 a9

  1. A9R72A8.tmp

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

  2. A=8-10, 2004 evaluation

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8 - 10 (2004TI06) (TUNL Manuscript from 2004) An evaluation of A = 8 - 10 was published in Nuclear Physics A745 (2004) p.155. The version here lacks the introduction and overview tables that appeared in the full version, and is arranged in a different manner. The figures are now present in the pdf documents, and are also available elsewhere on this server (see below). PDF HTML Figures A = 8 8n, 8He, 8Li, 8Be, 8B, 8C A = 8 A = 9 9He, 9Li, 9Be, 9B, 9C, 9N A = 9 A = 10 10n, 10He, 10Li, 10Be, 10B,

  3. Energy Level Diagrams A=9

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    9 Available in the following years: (2004), (1988), (1984), (1979), (1974), (1966), (1959) A=9 Energy Level Diagrams from (2004TI06) GIF (Graphic Interchange Format): 9Li (24 KB) 9Be (44 KB) 9B (36 KB) 9C (20 KB) Isobar diagram (36 KB) PDF (Portable Document Format): 9Li (36 KB) 9Be (60 KB) 9B (48 KB) 9C (28 KB) Isobar diagram (56 KB) EPS (Encapsulated Postscript): 9Li (1.7 MB) 9Be (1.7 MB) 9B (1.6 MB) 9C (1.7 MB) Isobar diagram (1.8 MB) A=9 Energy Level Diagrams from (1988AJ01) GIF (Graphic

  4. Energy Level Diagrams A=8

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8 Available in the following years: (2004), (1988), (1984), (1979), (1974), (1966), (1959) A=8 Energy Level Diagrams from (2004TI06) GIF (Graphic Interchange Format): 8He (20 KB) 8Li (194 KB) 8Be (44 KB) 8B (24 KB) Isobar diagram (36 KB) PDF (Portable Document Format): 8He (28 KB) 8Li (703 KB) 8Be (60 KB) 8B (32 KB) Isobar diagram (48 KB) EPS (Encapsulated Postscript): 8He (1.7 MB) 8Li (1.1 MB) 8Be (1.5 MB) 8B (1.4 MB) Isobar diagram (1.5 MB) A=8 Energy Level Diagrams from (1988AJ01) GIF

  5. A=9He (1974AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4AJ01) (Not illustrated) 9He is predicted to be particle unstable: its calculated mass excess > 40.17 MeV (1970WA1G, 1972WA07), = 43.54 MeV (1972TH13). Particle instability with respect to 8He + n, 7He + 2n and 6He + 3n implies atomic mass excesses greater than 39.7, 42.25 and 41.812 MeV, respectively. See also (1968CE1A). 9He has not been observed in a pion experiment [9Be(π-, π+)9He] (1965GI10) nor in the spontaneous fission of 252Cf (1967CO1K

  6. A=8B (66LA04)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8B (66LA04) (See Energy Level Diagrams for 8B) GENERAL: See (FO58D, TA60L, IN62, NA63E, BA64I, BA64GG, GR64C, ST64). See also Table 8.18 [Table of Energy Levels] (in PDF or PS). 1. 8B(β+)8Be Qm = 17.979 The beta decay leads mainly to 8Be*(2.9). Reported half lives are listed in Table 8.19 (in PDF or PS); taking τ1/2 = 0.774 sec and Q = 17.979 - 2.90, ft = 4.41 x 105 (BA65K). There is also observed a branch to a 8Be state at ~ 16.6 MeV; log ft = 2.9 (MA64D). See also (BA64GG) and 8Be. 2.

  7. A=9Li (66LA04)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    66LA04) (See Energy Level Diagrams for 9Li) GENERAL: See (GR64C). See also Table 9.1 [Table of Energy Levels] (in PDF or PS). Mass of 9Li: From the Q-value for 7Li(t, p)9Li: Q = -2.397 ± 0.020 MeV, the mass excess of 9Li is 24.965 ± 0.020 MeV (MI64E, MA65A). 1. 9Li(β-)9Be Qm = 13.615 9Li decays to the ground state (25 ± 15 %) and to the 2.43 MeV, neutron-unstable state of 9Be (75 ± 15 %). The β-endpoints are 13.5 ± 0.3 MeV and 11.0 ± 0.4 MeV; log ft = 5.5 ± 0.2 and 4.7 ± 0.2,

  8. Data:9a9d5422-780b-494c-9861-620f033009a8 | Open Energy Information

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    under review by our subject matter experts. Jump to: navigation, search Loading... 1. Basic Information 2. Demand 3. Energy << Previous 1 2 3 Next >> Basic Information...

  9. Categorical Exclusion Determinations: A8 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    A8 Categorical Exclusion Determinations: A8 Existing Regulations A8: Awards of certain contracts Awards of contracts for technical support services, management and operation of a government-owned facility, and personal services. Previous Regulations Categorical Exclusion Determinations dated before November 14th, 2011 were issued under previous DOE NEPA regulations. See the Notice of Final Rulemaking (76 FR 63763, 10/13/2011) for information changes to this categorical exclusion. DOCUMENTS

  10. Attachment A1

    Office of Environmental Management (EM)

    A1 CONTAINER STORAGE Waste Isolation Pilot Plant Hazardous Waste Permit October 2013 (This page intentionally blank) Waste Isolation Pilot Plant Hazardous Waste Permit October 2013 ...

  11. Appendix A-1

    Broader source: Energy.gov (indexed) [DOE]

    A-1 Table -1 This scale is created to provide a guide for the physician determination of ability to work for HRP certified persons with certain conditions and while taking certain ...

  12. Structural and functional characterization of the hazelnut allergen Cor a 8

    SciTech Connect (OSTI)

    Offermann, Lesa R.; Bublin, Merima; Perdue, Makenzie L.; Pfeifer, Sabine; Dubiela, Pawel; Borowski, Tomasz; Chruszcz, Maksymilian; Hoffmann-Sommergruber, Karin

    2015-09-28

    Nonspecific lipid transfer proteins (nsLTPs) are basic proteins, stabilized by four disulfide bonds, and are expressed throughout the plant kingdom. These proteins are also known as important allergens in fruits and tree nuts. In this study, the nsLTP from hazelnuts, Cor a 8, was purified and its crystal structure determined. The protein is stable at low pH and refolds after thermal denaturation. Molecular dynamics simulations were used to provide an insight into conformational changes of Cor a 8 upon ligand binding. When known epitope areas from Pru p 3 were compared to those of Cor a 8, differences were obvious, which may contribute to limited cross-reactivity between peach and hazelnut allergens. The differences in epitope regions may contribute to limited cross-reactivity between Cor a 8 and nsLTPs from other plant sources. The structure of Cor a 8 represents the first resolved structure of a hazelnut allergen.

  13. Structural and functional characterization of the hazelnut allergen Cor a 8

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Offermann, Lesa R.; Bublin, Merima; Perdue, Makenzie L.; Pfeifer, Sabine; Dubiela, Pawel; Borowski, Tomasz; Chruszcz, Maksymilian; Hoffmann-Sommergruber, Karin

    2015-09-28

    Nonspecific lipid transfer proteins (nsLTPs) are basic proteins, stabilized by four disulfide bonds, and are expressed throughout the plant kingdom. These proteins are also known as important allergens in fruits and tree nuts. In this study, the nsLTP from hazelnuts, Cor a 8, was purified and its crystal structure determined. The protein is stable at low pH and refolds after thermal denaturation. Molecular dynamics simulations were used to provide an insight into conformational changes of Cor a 8 upon ligand binding. When known epitope areas from Pru p 3 were compared to those of Cor a 8, differences were obvious,more » which may contribute to limited cross-reactivity between peach and hazelnut allergens. The differences in epitope regions may contribute to limited cross-reactivity between Cor a 8 and nsLTPs from other plant sources. The structure of Cor a 8 represents the first resolved structure of a hazelnut allergen.« less

  14. Table A9. Total Primary Consumption of Energy for All Purposes by Census

    U.S. Energy Information Administration (EIA) Indexed Site

    A9. Total Primary Consumption of Energy for All Purposes by Census" " Region and Economic Characteristics of the Establishment, 1991" " (Estimates in Btu or Physical Units)" ,,,,,,,,"Coke" " "," ","Net","Residual","Distillate","Natural Gas(d)"," ","Coal","and Breeze"," ","RSE" " ","Total","Electricity(b)","Fuel

  15. "Table A8. Selected Energy Operating Ratios for Total Energy Consumption for"

    U.S. Energy Information Administration (EIA) Indexed Site

    A8. Selected Energy Operating Ratios for Total Energy Consumption for" " Heat, Power, and Electricity Generation by Census Region, Industry Group, and" " Selected Industries, 1991" ,,,,,"Major" ,,,,"Consumption","Byproducts(b)" ,,,"Consumption","per Dollar","as a","Fuel Oil(c) as" ,,"Consumption","per Dollar","of Value","Percent of","a Percent

  16. Appendix A-1 Contract Performance Reports ARRA

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    A-1 Contract Performance Reports ARRA December 2011 CHPRC-2011-12, Rev. 0 Contract DE-AC06-08RL14788 Deliverable C.3.1.3.1 - 1 Format 1 - Work Breakdown Structure Format 3 -...

  17. A 1-Joule laser for a 16-fiber injection system

    SciTech Connect (OSTI)

    Honig, J

    2004-04-06

    A 1-J laser was designed to launch light down 16, multi-mode fibers (400-{micro}m-core dia.). A diffractive-optic splitter was designed in collaboration with Digital Optics Corporation (DOC), and was delivered by DOC. Using this splitter, the energy injected into each fiber varied <1%. The spatial profile out of each fiber was such that there were no ''hot spots,'' a flyer could successfully be launched and a PETN pellet could be initiated. Preliminary designs of the system were driven by system efficiency where a pristine TEM{sub 00} laser beam would be required. The laser is a master oscillator, power amplifier (MOPA) consisting of a 4-mm-dia. Nd:YLF rod in the stable, q-switched oscillator and a 9.5-mm-dia. Nd:YLF rod in the double-passed amplifier. Using a TEM{sub 00} oscillator beam resulted in excellent transmission efficiencies through the fibers at lower energies but proved to be quite unreliable at higher energies, causing premature fiber damage, flyer plate rupture, stimulated Raman scattering (SRS), and stimulated Brillouin scattering (SBS). Upon further investigation, it was found that both temporal and spatial beam formatting of the laser were required to successfully initiate the PETN. Results from the single-mode experiments, including fiber damage, SRS and SBS losses, will be presented. In addition, results showing the improvement that can be obtained by proper laser beam formatting will also be presented.

  18. A9_ISO

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    November 2014 1 November 2014 Short-Term Energy Outlook (STEO) Highlights  North Sea Brent crude oil spot prices fell from $95/barrel (bbl) on October 1 to $84/bbl at the end of the month. The causes included weakening outlooks for global economic and oil demand growth, the return to the market of previously disrupted Libyan crude oil production, and continued growth in U.S. tight oil production. Brent crude oil spot prices averaged $87/bbl in October, the first month Brent prices have

  19. A=9 Nuclides

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    A short list of corrections to mistakes found after the evaluation was published Elsevier Electronic Online: Elsevier (Nuclear Physics A) has made available PDF versions of A...

  20. A = 9 General Tables

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The General Table for 9Li is subdivided into the following categories: Shell Model Cluster Model Theoretical Ground State Properties Special States Other Model Calculations...

  1. a8.xls

    U.S. Energy Information Administration (EIA) Indexed Site

    ......... 6,922 5,613 1,028 Q Q N 223 5,001 to 10,000 ...... 7,033 5,304 1,383 Q N Q Q 10,001 to 25,000 ......

  2. A8_ISO

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

  3. A=8 Nuclides

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    A short list of corrections to mistakes found after the evaluation was published Elsevier Electronic Online: Elsevier (Nuclear Physics A) has made available PDF versions of A...

  4. A = 8 General Tables

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    subdivided into the following categories: Reviews Ground-state Properties Shell Model Cluster Model Other Theoretical Work Elastic and Inelastic Scattering b-decay Nuclear Spatial...

  5. Microsoft Word - 7A1.doc

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    6 Figure 1 Crystal structure of the 7A1 Fab' cocaine complex with the secondary structure of the antibody light (L) and heavy (H) chains colored in cyan. Substrate cocaine is also shown in spheres with yellow carbons, blue nitrogen, and red oxygens in the active site. High Resolution Snapshots for the Complete Reaction Cycle of a Cocaine Catalytic Antibody Xueyong Zhu 1 , Tobin J. Dickerson 2,3 , Claude J. Rogers 2,3 , Gunnar F. Kaufmann 2,3 , Jenny M. Mee 2,3 , Kathleen M. McKenzie 2,3 , Kim D.

  6. Decommissioning Project of Bohunice A1 NPP

    SciTech Connect (OSTI)

    Stubna, M.; Pekar, A.; Moravek, J.; Spirko, M.

    2002-02-26

    The first (pilot) nuclear power plant A1 in the Slovak Republic, situated on Jaslovske Bohunice site (60 km from Bratislava) with the capacity of 143 MWel, was commissioned in 1972 and was running with interruptions till 1977. A KS 150 reactor (HWGCR) with natural uranium as fuel, D2O as moderator and gaseous CO2 as coolant was installed in the A1 plant. Outlet steam from primary reactor coolant system with the temperature of 410 C was led to 6 modules of steam generators and from there to turbine generators. Refueling was carried out on-line at plant full power. The first serious incident associated with refueling occurred in 1976 when a locking mechanism at a fuel assembly failed. The core was not damaged during that incident and following a reconstruction of the damaged technology channel, the plant continued in operation. However, serious problems were occurring with the integrity of steam generators (CO2 gas on primary side, water and steam on secondary side) when the plant had to be shut down frequently due to failures and subsequent repairs. The second serious accident occurred in 1977 when a fuel assembly was overheated with a subsequent release of D2O into gas cooling circuit due to a human failure in the course of replacement of a fuel assembly. Subsequent rapid increase in humidity of the primary system resulted in damages of fuel elements in the core and the primary system was contaminated by fission products. In-reactor structures had been damaged, too. Activity had penetrated also into certain parts of the secondary system via leaking steam generators. Radiation situation in the course of both events on the plant site and around it had been below the level of limits specified. Based on a technical and economical justification of the demanding character of equipment repairs for the restoration of plant operation, and also due to a decision made not to continue with further construction of gas cooled reactors in Czechoslovakia, a decision was made in

  7. A 1-D dusty plasma photonic crystal

    SciTech Connect (OSTI)

    Mitu, M. L.; Ticoş, C. M.; Toader, D.; Banu, N.; Scurtu, A.; Department of Physics, University of Bucharest, 077125 Bucharest

    2013-09-21

    It is demonstrated numerically that a 1-D plasma crystal made of micron size cylindrical dust particles can, in principle, work as a photonic crystal for terahertz waves. The dust rods are parallel to each other and arranged in a linear string forming a periodic structure of dielectric-plasma regions. The dispersion equation is found by solving the waves equation with the boundary conditions at the dust-plasma interface and taking into account the dielectric permittivity of the dust material and plasma. The wavelength of the electromagnetic waves is in the range of a few hundred microns, close to the interparticle separation distance. The band gaps of the 1-D plasma crystal are numerically found for different types of dust materials, separation distances between the dust rods and rod diameters. The distance between levitated dust rods forming a string in rf plasma is shown experimentally to vary over a relatively wide range, from 650 μm to about 1350 μm, depending on the rf power fed into the discharge.

  8. Data:B0c510db-7e64-4d8c-a9ae-f8521cbb8489 | Open Energy Information

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    d8c-a9ae-f8521cbb8489 No revision has been approved for this page. It is currently under review by our subject matter experts. Jump to: navigation, search Loading... 1. Basic...

  9. OSU-A9 inhibits angiogenesis in human umbilical vein endothelial cells via disrupting AktNF-?B and MAPK signaling pathways

    SciTech Connect (OSTI)

    Omar, Hany A.; Arafa, El-Shaimaa A.; Salama, Samir A.; Arab, Hany H.; Wu, Chieh-Hsi; Weng, Jing-Ru

    2013-11-01

    Since the introduction of angiogenesis as a useful target for cancer therapy, few agents have been approved for clinical use due to the rapid development of resistance. This problem can be minimized by simultaneous targeting of multiple angiogenesis signaling pathways, a potential strategy in cancer management known as polypharmacology. The current study aimed at exploring the anti-angiogenic activity of OSU-A9, an indole-3-carbinol-derived pleotropic agent that targets mainly Aktnuclear factor-kappa B (NF-?B) signaling which regulates many key players of angiogenesis such as vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs). Human umbilical vein endothelial cells (HUVECs) were used to study the in vitro anti-angiogenic effect of OSU-A9 on several key steps of angiogenesis. Results showed that OSU-A9 effectively inhibited cell proliferation and induced apoptosis and cell cycle arrest in HUVECs. Besides, OSU-A9 inhibited angiogenesis as evidenced by abrogation of migration/invasion and Matrigel tube formation in HUVECs and attenuation of the in vivo neovascularization in the chicken chorioallantoic membrane assay. Mechanistically, Western blot, RT-PCR and ELISA analyses showed the ability of OSU-A9 to inhibit MMP-2 production and VEGF expression induced by hypoxia or phorbol-12-myristyl-13-acetate. Furthermore, dual inhibition of AktNF-?B and mitogen-activated protein kinase (MAPK) signaling, the key regulators of angiogenesis, was observed. Together, the current study highlights evidences for the promising anti-angiogenic activity of OSU-A9, at least in part through the inhibition of AktNF-?B and MAPK signaling and their consequent inhibition of VEGF and MMP-2. These findings support OSU-A9's clinical promise as a component of anticancer therapy. - Highlights: The antiangiogenic activity of OSU-A9 in HUVECs was explored. OSU-A9 inhibited HUVECs proliferation, migration, invasion and tube formation. OSU-A9 targeted signaling

  10. Data:160c06ef-99c8-45a6-9685-727a8ae18799 | Open Energy Information

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    a8ae18799 No revision has been approved for this page. It is currently under review by our subject matter experts. Jump to: navigation, search Loading... 1. Basic Information 2....

  11. Data:2c616412-ed1f-456f-89e9-eb55212a8a96 | Open Energy Information

    Open Energy Info (EERE)

    eb55212a8a96 No revision has been approved for this page. It is currently under review by our subject matter experts. Jump to: navigation, search Loading... 1. Basic Information 2....

  12. TU-A-9A-10: Verification of Photoacoustic Computed Tomography Perfusion Imaging Using DCE-CT

    SciTech Connect (OSTI)

    Roth, A; Krutulis, M; Verleker, A; Stantz, K

    2014-06-15

    Purpose: We propose to verify quantifiable perfusion information generated by a Photoacoustic Computed Tomography (PCT) scanner using Dynamic Contrast-Enhanced CT (DCE-CT), and to investigate physicsbased models of acoustic properties of tissue and photon transport to improve quantification. These corrections first necessitate a skin identifying algorithms to reduce speed-of-sound blurring and empirical photon correction methods. Methods: Xenograft mice (n=5) of breast cancer was imaged using DCE-CT which was followed by DCE-PCT. To obtain CT perfusion data, each mouse was i.v. injected (0.2mL Isovue @0.5mL/min) and subsequent radio-opaque time curves fit to a 2-compartmental model on a voxel-wise basis. For DCE-PCT, different concentrations of ICG (250, 125, and 62.5 micro-Molar) were injected at the same rate, but also acquired at different sampling rates (3, 6, and 12 seconds). The time intensity curves from PCT were fit to a 1-compartmental model on a voxel by voxel basis. The images were coregistered (Oncentra) based on the structural similarities of the tumor vasculature after which we compared both the contrastenhanced dynamics and the vascular physiology. Results: Moderate to high doses of ICG impact the washin phase of the PCT contrast due to photon losses as a function of depth. A semi-automatic algorithm has been developed to identify the skin margin, and subsequent MC and empirical models of photon transport and variations in speed-of-sound are being evaluated. Conclusion: From our results we find that there is a need to apply photon and speed-of-sound corrections to our PCT data to improve the quantifiable image data at depth in the tumor for PCT. The dose and injection rate may help in reducing large systematic effects. Our project is partially funded by a NIH SBIR grant.

  13. File:FormA1.pdf | Open Energy Information

    Open Energy Info (EERE)

    FormA1.pdf Jump to: navigation, search File File history File usage File:FormA1.pdf Size of this preview: 463 599 pixels. Other resolution: 464 600 pixels. Full resolution...

  14. A9R7296.tmp

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

  15. A9R7298.tmp

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

  16. A9_ISO.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

  17. A9_iso.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

  18. A8_ISO.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

  19. A8_iso.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

  20. Categorical Exclusion Determinations: A1 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Categorical Exclusion Determinations: A1 Existing Regulations A1: Routine DOE business actions Routine actions necessary to support the normal conduct of DOE business limited to administrative, financial, and personnel actions. Previous Regulations Categorical Exclusion Determinations dated before November 14th, 2011 were issued under previous DOE NEPA regulations. See the Notice of Final Rulemaking (76 FR 63763, 10/13/2011) for information changes to this categorical exclusion. DOCUMENTS

  1. Consumer Refrigerators-Freezers (Appendix A1) | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Refrigerators-Freezers (Appendix A1) Consumer Refrigerators-Freezers (Appendix A1) The Department of Energy (DOE) develops standardized data templates for reporting the results of tests conducted in accordance with current DOE test procedures. Templates may be used by third-party laboratories under contract with DOE that conduct testing in support of ENERGY STAR® verification, DOE rulemakings, and enforcement of the federal energy conservation standards. Consumer Refrigerators-Freezers Appendix

  2. Quantum of area {Delta}A=8{pi}l{sub P}{sup 2} and a statistical interpretation of black hole entropy

    SciTech Connect (OSTI)

    Ropotenko, Kostiantyn

    2010-08-15

    In contrast to alternative values, the quantum of area {Delta}A=8{pi}l{sub P}{sup 2} does not follow from the usual statistical interpretation of black hole entropy; on the contrary, a statistical interpretation follows from it. This interpretation is based on the two concepts: nonadditivity of black hole entropy and Landau quantization. Using nonadditivity a microcanonical distribution for a black hole is found and it is shown that the statistical weight of a black hole should be proportional to its area. By analogy with conventional Landau quantization, it is shown that quantization of a black hole is nothing but the Landau quantization. The Landau levels of a black hole and their degeneracy are found. The degree of degeneracy is equal to the number of ways to distribute a patch of area 8{pi}l{sub P}{sup 2} over the horizon. Taking into account these results, it is argued that the black hole entropy should be of the form S{sub bh}=2{pi}{center_dot}{Delta}{Gamma}, where the number of microstates is {Delta}{Gamma}=A/8{pi}l{sub P}{sup 2}. The nature of the degrees of freedom responsible for black hole entropy is elucidated. The applications of the new interpretation are presented. The effect of noncommuting coordinates is discussed.

  3. Evaluation of LLTR Series II tests A-1A and A-1B test results. [Large Leak Test Rig

    SciTech Connect (OSTI)

    Shoopak, B F; Amos, J C; Norvell, T J

    1980-03-01

    The standard methodology, with minor modifications provides conservative yet realistic predictions of leaksite and other sodium system pressures in the LLTR Series II vessel and piping. The good agreement between predicted and measured pressures indicates that the TRANSWRAP/RELAP modeling developed from the Series I tests is applicable to larger scale units prototypical of the Clinch River steam generator design. Calculated sodium system pressures are sensitive to several modeling parameters including rupture disc modeling, acoustic velocity in the test vessel, and flow rate from the rupture tube. The acoustic velocity which produced best agreement with leaksite pressures was calculated based on the shroud diameter and shroud wall thickness. The corresponding rupture tube discharge coefficient was that of the standard design methodology developed from Series I testing. As found in Series I testing, the Series II data suggests that the leading edge of the flow in the relief line is two phase for a single, doubled-ended guillotine tube rupture. The steam generator shroud acts as if it is relatively transparent to the transmission of radial pressures to the vessel wall. Slightly lower sodium system maximum pressures measured during Test A-1b compared to Test A-1a are attributed to premature failure (failure at a lower pressure) of the rupture disc in contact with the sodium for test A-1b. The delay in failure of the second disc in Test A-1b, which was successfully modeled with TRANSWRAP, is attributed to the limited energy in the nitrogen injection.

  4. Liver X receptor alpha mediated genistein induction of human dehydroepiandrosterone sulfotransferase (hSULT2A1) in Hep G2 cells

    SciTech Connect (OSTI)

    Chen, Yue; Zhang, Shunfen; Zhou, Tianyan; Huang, Chaoqun; McLaughlin, Alicia; Chen, Guangping

    2013-04-15

    Cytosolic sulfotransferases are one of the major families of phase II drug metabolizing enzymes. Sulfotransferase-catalyzed sulfonation regulates hormone activities, metabolizes drugs, detoxifies xenobiotics, and bioactivates carcinogens. Human dehydroepiandrosterone sulfotransferase (hSULT2A1) plays important biological roles by sulfating endogenous hydroxysteroids and exogenous xenobiotics. Genistein, mainly existing in soy food products, is a naturally occurring phytoestrogen with both chemopreventive and chemotherapeutic potential. Our previous studies have shown that genistein significantly induces hSULT2A1 in Hep G2 and Caco-2 cells. In this study, we investigated the roles of liver X receptor (LXRα) in the genistein induction of hSULT2A1. LXRs have been shown to induce expression of mouse Sult2a9 and hSULT2A1 gene. Our results demonstrate that LXRα mediates the genistein induction of hSULT2A1, supported by Western blot analysis results, hSULT2A1 promoter driven luciferase reporter gene assay results, and mRNA interference results. Chromatin immunoprecipitation (ChIP) assay results demonstrate that genistein increase the recruitment of hLXRα binding to the hSULT2A1 promoter. These results suggest that hLXRα plays an important role in the hSULT2A1 gene regulation. The biological functions of phytoestrogens may partially relate to their induction activity toward hydroxysteroid SULT. - Highlights: ► Liver X receptor α mediated genistein induction of hSULT2A1 in Hep G2 cells. ► LXRα and RXRα dimerization further activated this induction. ► Western blot results agreed well with luciferase reporter gene assay results. ► LXRs gene silencing significantly decreased hSULT2A1 expression. ► ChIP analysis suggested that genistein enhances hLXRα binding to the hSULT2A1 promoter.

  5. Load partitioning between ferrite/martensite and dispersed nanoparticles of a 9Cr ferritic/martensitic (F/M) ODS steel at high temperatures

    SciTech Connect (OSTI)

    Zhang, Guangming; Mo, Kun; Miao, Yinbin; Liu, Xiang; Almer, Jonathan; Zhou, Zhangjian; Stubbins, James F.

    2015-06-18

    In this study, a high-energy synchrotron radiation X-ray technique was used to investigate the tensile deformation processes of a 9Cr-ODS ferritic/martensitic (F/M) steel at different temperatures. Two minor phases within the 9Cr-ODS F/M steel matrix were identified as Y2Ti2O7 and TiN by the high-energy X-ray diffraction, and confirmed by the analysis using energy dispersive X-ray spectroscopy (EDS) of scanning transmission electron microscope (STEM). The lattice strains of the matrix and particles were measured through the entire tensile deformation process. During the tensile tests, the lattice strains of the ferrite/martensite and the particles (TiN and Y2Ti2O7) showed a strong temperature dependence, decreasing with increasing temperature. Analysis of the internal stress at three temperatures showed that the load partitioning between the ferrite/martensite and the particles (TiN and Y2Ti2O7) was initiated during sample yielding and reached to a peak during sample necking. At three studied temperatures, the internal stress of minor phases (Y2Ti2O7 and TiN) was about 2 times that of F/M matrix at yielding position, while the internal stress of Y2Ti2O7 and TiN reached about 4.5-6 times and 3-3.5 times that of the F/M matrix at necking position, respectively. It indicates that the strengthening of the matrix is due to minor phases (Y2Ti2O7 and TiN), especially Y2Ti2O7 particles. Although the internal stresses of all phases decreased with increasing temperature from RT to 600 degrees C, the ratio of internal stresses of each phase at necking position stayed in a stable range (internal stresses of Y2Ti2O7 and TiN were about 4.5-6 times and 3-3.5 times of that of F/M matrix, respectively). The difference between internal stress of the F/M matrix and the applied stress at 600 degrees C is slightly lower than those at RI and 300 degrees C, indicating that the nanoparticles still have good strengthening effect at 600 degrees C. (C) 2015 Elsevier B.V. All rights reserved.

  6. Data:B831a092-b2f7-4f35-957e-d1fa374af3a8 | Open Energy Information

    Open Energy Info (EERE)

    f35-957e-d1fa374af3a8 No revision has been approved for this page. It is currently under review by our subject matter experts. Jump to: navigation, search Loading... 1. Basic...

  7. Superfund Record of Decision (EPA Region 1): Fort Devens-Sudbury Training Annex (areas of contamination A4, A7, and A9), Middlesex County, MA, September 30, 1997

    SciTech Connect (OSTI)

    1998-01-01

    The US Army Sudbury Annex (the Annex) is a National Priorities List (NPL) site under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). This Record of Decision addresses past releases of contaminants to all media at area of contamination (AOC) A4-Waste Dump, and past releases to groundwater at AOC A7-Old Gravel Pit Landfill and AOC A9-Petroleum, Oil, and Lubricant (POL) Burn Area.

  8. A9R729A.tmp

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    Gasoline and Diesel Fuel Update (EIA)

    Real Gross State Product (Billion $2009) New England ................ 858 869 863 867 869 874 878 883 888 892 896 901 864 876 894 Middle Atlantic .............. 2,399 2,435 2,450 2,455 2,459 2,473 2,487 2,499 2,507 2,519 2,531 2,542 2,435 2,479 2,525 E. N. Central ................. 2,236 2,250 2,269 2,277 2,278 2,288 2,298 2,309 2,322 2,333 2,344 2,353 2,258 2,293 2,338 W. N. Central ................ 1,048 1,055 1,057 1,058 1,060 1,066 1,072 1,078 1,084 1,090 1,096 1,102 1,054 1,069 1,093 S.

  20. A=9Be (1984AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Energy Levels (in PDF or PS). Shell model: (1978AR1H, 1979LA06, 1981BO1Y, 1982OR03). Cluster and -particle models: (1978AR1H, 1978RE1A, 1979CH1D, 1979FO16, 1979LU1A, 1979OK02,...

  1. A=9Be (1979AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    PDF or PS). Shell model: (1975KU27, 1975SC1K, 1977CA08, 1977JA14, 1978BO31). and cluster models: (1974CH19, 1974GR42, 1974PA1B, 1975AB1E, 1975CH28, 1975KR1D, 1975RO1B,...

  2. A=9Be (66LA04)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    excited state is 4 times less (HO61G: see also (JA57)). Angular distributions for both groups show maxima in the forward hemisphere. It is suggested that the large cross section...

  3. A=9B (1974AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4AJ01) (See Energy Level Diagrams for 9B) GENERAL: See also (1966LA04) and Table 9.9 [Table of Energy Levels] (in PDF or PS). Model calculations: (1966BA26, 1966EL08, 1967ST1C, 1971CO28, 1972LE1L, 1973HA49). Special levels: (1966BA26, 1966EL08, 1967BA59, 1967ST1C, 1969HA1G, 1970TO1E, 1971CO28, 1971LI30, 1972BE1E). Astrophysical questions: (1970BA1M). Other topics: (1967CA17, 1967CH1H, 1970SA05, 1972AN05, 1972HA57, 1972CA37, 1972LE1L, 1972PN1A, 1973JU2A). Ground state properties: (1966BA26,

  4. A=9B (1979AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    9AJ01) (See Energy Level Diagrams for 9B) GENERAL: See also (1974AJ01) and Table 9.9 [Table of Energy Levels] (in PDF or PS). Model calculations: (1977HO1F, 1977OK01, 1978HO1E). Special levels: (1974IR04, 1975WI1E, 1976IR1B, 1978HO1E). Astrophysical questions: (1977SI1D). Pion reactions: (1974KA07). Other topics: (1974HA1C, 1974IR04, 1976IR1B). Ground state properties: (1975BE31, 1977OK01). 1. (a) 6Li(3He, n)8B Qm = -1.975 Eb = 16.603 (b) 6Li(3He, p)8Be Qm = 16.7878 (c) 6Li(3He, d)7Be Qm = 0.113

  5. A=9B (1984AJ01)

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    4AJ01) (See Energy Level Diagrams for 9B) GENERAL: See also (1979AJ01) and Table 9.9 [Table of Energy Levels] (in PDF or PS). Model calculations: (1978AR1H, 1979LA06, 1979MA1J, 1981KO1Q). Special states: (1981KO1Q). Reactions involving pions: (1978WA1B, 1979AL1J, 1982EL07, 1982HI02, 1983HU02). Hypernuclei: (1978PO1A, 1978SO1A, 1979MA1L, 1981WA1J, 1982KO11). Other topics: (1979BE1H, 1979LA06, 1982NG01). Ground state of 9B: (1982NG01). 1. (a) 6Li(3He, γ)9B Qm = 16.601 (b) 6Li(3He, n)8B Qm =

  6. A=9B (1988AJ01)

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    8AJ01) (See Energy Level Diagrams for 9B) GENERAL: See also (1984AJ01) and Table 9.9 [Table of Energy Levels] (in PDF or PS). Model calculations: (1983SH38, 1987VOZU). Special states: (1983AU1B, 1983FE07, 1983GO28, 1984KO40, 1985PO18, 1985PO19, 1985SH24, 1986AN07, 1987BA54, 1987VOZU). Complex reactions involving 9B: (1985PO18, 1985PO19, 1987AR19, 1987PO03). Reactions involving pions: (1985PN01). Hypernuclei: (1982KA1D, 1983KO1D, 1983SH38, 1983SH1E, 1984ZH1B, 1985AH1A, 1985PN01, 1986DA1B,

  7. A=9B (2004TI06)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2004TI06) (See Energy Level Diagrams for 9B) GENERAL: References to articles on general properties of 9B published since the previous review (1988AJ01) are grouped into categories and listed, along with brief descriptions of each item, in the General Tables for 9B located on our website at (www.tunl.duke.edu/nucldata/General_Tables/9b.shtml). See also Table Prev. Table 9.13 preview 9.13 [Table of Energy Levels] (in PDF or PS). The low-lying levels of 9B have mainly [441] spatial symmetry and

  8. A=9B (59AJ76)

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    59AJ76) (See the Energy Level Diagram for 9B) GENERAL: See also Table 9.4 [Table of Energy Levels] (in PDF or PS). 1. 6Li(3He, p)8Be Qm = 16.786 Eb = 16.598 The excitation functions for protons leading to the ground and 2.9-MeV excited states of 8Be have been measured for E(3He) = 0.9 to 5.1 MeV (θ = 0° and 150°, lab.). Resonances are observed at E(3He) = 1.6 MeV (Γ = 0.25 MeV, 9B* = 17.6 MeV) and 3.0 MeV (Γ = 1.5 MeV, 9B* = 18.6 MeV) (SC56F). However, J.W. Butler (private communication)

  9. A=9B (66LA04)

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    66LA04) (See Energy Level Diagrams for 9B) GENERAL: See (BA59N, PH60A, SP60, TA60L, BA62G, IN62, GR64C, RE64A, ST64). See also Table 9.10 [Table of Energy Levels] (in PDF or PS). 1. (a) 6Li(3He, p)8Be Qm = 16.787 Eb = 16.601 (b) 6Li(3He, n)8B Qm = -1.975 The excitation functions for protons leading to the ground and 2.9 MeV states of 8Be (p0 and p1) have been measured for E(3He) = 0.9 to 17 MeV. Resonances are reported at E(3He) = 1.6 MeV (Γ = 0.25 MeV) and E(3He) = 3.0 MeV (Γ = 1.5 MeV)

  10. A=9Be (1974AJ01)

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    4AJ01) (See Energy Level Diagrams for 9Be) GENERAL: See also (1966LA04) and Table 9.2 [Table of Energy Levels] (in PDF or PS). Shell model: (1961KO1A, 1965CO25, 1965GR18, 1965VO1A, 1966AD06, 1966BA26, 1966HA18, 1966MA1P, 1966WI1E, 1967CO32, 1967ST1C, 1968GO01, 1969BO1V, 1969BO19, 1969BO33, 1969GU03, 1969VA1C, 1970CO1H, 1971CO28, 1971GR02, 1971NO02, 1972LE1L, 1973HA49, 1973KU03). Aplha and cluster models: (1965NE1B, 1966HI1A, 1967TA1C, 1968KU1B, 1969BA1J, 1969NE1C, 1970BA1Q, 1971LE1N, 1971NO02,

  11. A=9Be (1988AJ01)

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    1988AJ01) (See Energy Level Diagrams for 9Be) GENERAL: See also (1984AJ01) and Table 9.2 [Table of Energy Levels] (in PDF or PS). Shell model: (1983VA31, 1984VA06, 1984ZW1A, 1985AN16, 1987KI1C, 1988OR1C, 1988WO04). Cluster and α-particle models: (1981PL1A, 1982DZ1A, 1983JA09, 1983MI1E, 1983SH38, 1985HA1P, 1985KW02, 1986CR1B, 1987VOZU). Special states: (1981PL1A, 1983AU1B, 1983GO28, 1983MI08, 1983VA31, 1984BA49, 1984KO40, 1984VA06, 1984WO09, 1984ZW1A, 1985GO1A, 1985HA1J, 1985PO19, 1985SH24,

  12. A=9Be (2004TI06)

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    2004TI06) (See Energy Level Diagrams for 9Be) GENERAL: References to articles on general properties of 9Be published since the previous review (1988AJ01) are grouped into categories and listed, along with brief descriptions of each item, in the General Tables for 9Be located on our website at (www.tunl.duke.edu/nucldata/General_Tables/9be.shtml). See also Table Prev. Table 9.2 preview 9.2 [Table of Energy Levels] (in PDF or PS). μ = -1.1778 ± 0.0009 μN: see (1978LEZA); Q = 52.88 ± 0.38 mb:

  13. A=9Be (59AJ76)

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    59AJ76) (See the Energy Level Diagram for 9Be) GENERAL: See also Table 9.1 [Table of Energy Levels] (in PDF or PS). Theory: See (DA55D, FR55H, BL56A, DE56, KU56, BA57, PA57A, KU58B). 1. (a) 6Li(t, d)7Li Qm = 0.994 Eb = 17.687 (b) 6Li(t, p)8Li Qm = 0.803 (c) 6Li(t, n)8Be Qm = 16.021 (d) 6Li(t, α)5He Qm = 15.158 (e) 6Li(t, n)4He + 4He Qm = 16.115 The differential cross section at 90° for reaction (a) rises steeply from 8.8 mb/sr at Et = 0.72 MeV to 19 mb at 0.90 MeV, and then more slowly to 21

  14. A=9C (1974AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4AJ01) (See the Isobar Diagram for 9C) GENERAL: See also (1966LA04) and Table 9.12 [Table of Energy Levels] (in PDF or PS). Model calculations: (1966BA26). Other topics: (1966BA26, 1966MC1C, 1972AN05, 1972CA37, 1973LA19). Ground state properties, including theoretical mass predictions: (1965GO1D, 1966BA26, 1966GO1B, 1966KE16, 1969GA1P, 1969JA1M, 1972CE1A, 1973HA77). Mass of 9C: From the threshold energy of 7Be(3He, n)9C (1971MO01) the atomic mass excess of 9C is 28.908 ± 0.004 MeV. This value

  15. A=9C (1979AJ01)

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    9AJ01) (See the Isobar Diagram for 9C) GENERAL: See also (1974AJ01) and Table 9.12 [Table of Energy Levels] (in PDF or PS). Model calculations: (1974IR04, 1976IR1B). Pion reactions: (1974KA07, 1976HE1G, 1978SE1D). Other topics: (1974IR04, 1975BE56, 1976IR1B, 1977CE05). Ground state properties: (1975BE31). Mass of 9C: The atomic mass excess of 9C is 28912 ± 3 keV (1975KA18) based on the Q-value of the 12C(3He, 6He)9C reaction (1971TR03) and the threshold energy of the 7Be(3He, n)9C reaction

  16. A=9C (1984AJ01)

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    4AJ01) (See the Isobar Diagram for 9C) GENERAL: (See also (1979AJ01) for other references in this category and for some reactions on which no new work has been done.) and Table 9.12 [Table of Energy Levels] (in PDF or PS) here. Model calculations: (1979LA06). Complex reactions involving 9C: (1981MO20). Reactions involing pions: (1979AS01, 1979NA1E, 1980BU15, 1983HU02). Other topics: (1979BE1H, 1979LA06, 1982NG01). Mass of 9C: The recent Q0 value for the 12C(3He, 6He)9C reaction (see reaction 3)

  17. A=9C (1988AJ01)

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    8AJ01) (See the Isobar Diagram for 9C) GENERAL: See also (1984AJ01) and Table 9.11 [Table of Energy Levels] (in PDF or PS) here. Model calculations: (1983AU1B). Complex reactions involving 9C: (1983FR1A, 1983OL1A, 1986HA1B, 1987SN01). Reactions involving pions: (1983AS1B, 1984BR22, 1985PN01). Other topics: (1982KA1D, 1985AN28, 1986AN07). Ground state of 9C: (1983ANZQ, 1983AU1B, 1985AN28, 1987SA15). 1. 9C(β+)9B Qm = 16.498 The half-life of 9C is 126.5 ± 0.9 msec: see (1974AJ01). The decay is

  18. A=9C (2004TI06)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2004TI06) (See Energy Level Diagrams for 9C) GENERAL: References to articles on general properties of 9C published since the previous review (1988AJ01) are grouped into categories and listed, along with brief descriptions of each item, in the General Tables for 9C located on our website at (www.tunl.duke.edu/nucldata/General_Tables/9c.shtml). See also Table Prev. Table 9.16 preview 9.16 [Table of Energy Levels] (in PDF or PS). Ground state properties: μ = -1.3914 ± 0.0005 μN (1996MA38). See

  19. A=9C (59AJ76)

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    59AJ76) (Not illustrated) Comparison with the mass of 9Li leads to an estimated mass excess of 32.3 ± 2 MeV (55AJ61). Analysis of a single star attributed to β-decay of 9C and subsequent breakup into p + 2α yields Q > 15.4 MeV, mass excess > 30.2 MeV (SW56A). Stability against 8B + p requires a mass excess < 32.9 MeV. Two reactions leading to 9C which have not been reported are 7Be(3He, n)9C (Qm = -7) and 12C(γ, 3n)9C (Qm = -54

  20. A=9C (66LA04)

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    66LA04) (See the Isobar Diagram for 9C) GENERAL: See (55AJ61, SW56A, GR64C, WI64E, JA65C, WO65). Mass of 9C: The atomic mass excess of 9C is 28.99 ± 0.07 MeV: see 12C(3He, 6He)9C (CE65). 1. 9C(β+)9B → 8Be + p Qm = 16.76 Two groups of delayed protons are observed, indicating a component of the β+ decay to a level of 9B at 12.05 ± 0.2 MeV with Γ = 800 ± 100 keV which then decays to p + 8Be(0) and 8Be*(2.9). The half-life is 127 ± 3 msec. The allowed character of the decay suggests Jπ =

  1. A=9He (1979AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    9AJ01) (Not illustrated) 9He has not been observed: see (1974AJ01). It is predicted to be particle unstable. Particle instability with respect to 8He + n, 7He + 2n and 6He + 3n implies atomic mass excesses greater than 39.667, 42.253 and 41.808 MeV, respectively. The calculated mass excess of 9He is 43.49 MeV based on the modified form of the mass equation (1975JE02). See also (1974TH01) and (1974IR04, 1975BE31, 1976IR1B; theor.

  2. A=9He (1984AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4AJ01) (Not illustrated) 9He has been observed in the 9Be(π-, π+)9He reaction at Eπ- = 194 MeV; the atomic mass excess is 40.81 ± 0.12 MeV. 9He is then unstable with respect to decay into 8He + n by 1.14 MeV (1981SE1B, 1980NA1D, 1980SE1C, 1980SE1F). See also (1979AJ01) and (1982PO1C; hypernuclei) and (1982NG01; theor

  3. A=9He (1988AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8AJ01) (See the Isobar Diagram for 9He) 9He has been observed in the 9Be(14C, 14O) reaction at E(14C) = 158 MeV (1987BEYI) and in the 9Be(π-, π+) reaction at Eπ- = 180 and 194 MeV (1987SE05): the atomic mass excesses are 41.5 ± 1.0 MeV and 40.80 ± 0.10 MeV, respectively. We adopt the latter value. 9He is then unstable with respect to decay into 8He + n by 1.13 MeV. (1987SE05) also report the population of excited states of 9He at 1.2, 3.8 and 7.0 MeV, while (1987BEYI) suggest an excited

  4. A=9He (2004TI06)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2004TI06) (See the Isobar Diagram for 9He) GENERAL: References to articles on general properties of 9He published since the previous review (1988AJ01) are grouped into categories and listed, along with brief descriptions of each item, in the General Tables for 9He located on our website at (www.tunl.duke.edu/nucldata/General_Tables/9he.shtml). Mass of 9He: Although the value adopted in the 2003 Atomic Mass Evaluation (2003AU02) for the 9He ground state is 40.939 ± 0.029 MeV based on the results

  5. A=9Li (1974AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4AJ01) (See Energy Level Diagrams for 9Li) GENERAL: See also Table 9.1 [Table of Energy Levels] (in PDF or PS). Model calculations: (1966BA26). Special reactions: (1965DO13, 1966GA15, 1966KL1C, 1967AU1B, 1967CA1J, 1967HA10, 1968DO1C, 1972VO06, 1973KO1D, 1973MU12, 1973WI15). Other topics: (1972CA37, 1972PN1A, 1973JU2A). Ground state properties: (1966BA26, , 1969JA1M). Mass of 9Li: From the Q-value of 18O(7Li, 16O)9Li, the atomic mass excess of 9Li is 24.9654 ± 0.005 MeV (1969NE1E; prelim.

  6. A=9Li (1979AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    9AJ01) (See Energy Level Diagrams for 9Li) GENERAL: See also (1974AJ01) and Table 9.1 [Table of Energy Levels] (in PDF or PS). Model calculations: (1974IR04, 1976IR1B, 1977JA14). Special reactions: (1975AB1D, 1975ZE01, 1976AL1F, 1976BE67, 1976BU16, 1977YA1B). Pion and kaon reactions (See also reaction 3.): (1973CA1C, 1976TR1A, 1977BA1Q, 1977DO06, 1977SH1C). Other topics: (1970KA1A, 1973TO16, 1974IR04, 1975BE56, 1976IR1B). Ground state properties: (1975BE31). μ = 3.4359 ± 0.0010 nm (1976CO1L;

  7. A=9Li (1984AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4AJ01) (See Energy Level Diagrams for 9Li) GENERAL: See also (1979AJ01) and Table 9.1 [Table of Energy Levels] (in PDF or PS). Model calculations: (1979LA06). Complex reactions involving 9Li: (1978DU1B, 1979AL22, 1979BO22, 1979JA1C, 1980BO31, 1980WI1L, 1981BO1X, 1981MO20, 1982BO1Y). Muon and neutrino capture and reactions: (1980MU1B). Reactions involving pions and other mesons (See also reaction 3.): (1978FU09, 1979BO21, 1979PE1C, 1979WI1E, 1980NI03, 1980ST15, 1981YA1A). Hypernuclei: (1978DA1A,

  8. A=9Li (1988AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8AJ01) (See Energy Level Diagrams for 9Li) GENERAL: See also (1984AJ01) and Table 9.1 [Table of Energy Levels] (in PDF or PS). Model calculations: (1983KU17, 1984CH24, 1984VA06). Special states: (1983KU17, 1984VA06). Electromagnetic interactions: (1983KU17). Astrophysical questions: (1987MA2C). Complex reactions involving 9Li: (1983OL1A, 1983WI1A, 1984GR08, 1985JA1B, 1985MA02, 1985MO17, 1986CS1A, 1986HA1B, 1986SA30, 1986WE1C, 1987BA38, 1987CH26, 1987JA06, 1987KO1Z, 1987SH1K, 1987TAZU, 1987WA09,

  9. A=9Li (2004TI06)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2004TI06) (See Energy Level Diagrams for 9Li) GENERAL: References to articles on general properties of 9Li published since the previous review (1988AJ01) are grouped into categories and listed, along with brief descriptions of each item, in the General Tables for 9Li located on our website at (www.tunl.duke.edu/nucldata/General_Tables/9li.shtml). See also Table Prev. Table 9.1 preview 9.1 [Table of Energy Levels] (in PDF or PS). Ground state properties: μ = 3.4391 ± 0.0006 μN (1983CO11). See

  10. A=9Li (59AJ76)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    59AJ76) (Not illustrated) Mass of 9Li: From the threshold for 9Be(d, 2p)9Li, Ed = 19 ± 1 MeV (GA51C), the mass excess of 9Li is determined as M - A = 28.1 ± 1 MeV. 1. 9Li(β-)9Be* --> 8Be + n Qm = 12.4 9Li decays to excited states of 9Be which decay by neutron emission. The mean of the reported half-lives is 0.169 ± 0.003 sec (GA51C, HO52B). See also (SH52, FR53A, BE55D, FL56, TA58B). 2. 9Be(d, 2p)9Li Qm = -15.5 The threshold is 19 ± 1 MeV (GA51C). 3. 11B(γ, 2p)9Li Qm = -31.4 See (SH52,

  11. A=9N (1979AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    79AJ01) (Not illustrated) Not observed: see (1974IR04, 1975BE31, 1976IR1B

  12. A=9N (1984AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4AJ01) (Not illustrated) Not observed: see (1979AJ01). See also (1982NG01

  13. A=9N (1988AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8AJ01) (Not illustrated) Not observed: see (1984AJ01) and (1983ANZQ, 1986AN40

  14. A=9N (2004TI06)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2004TI06) (Not illustrated) Not observed: see (1988AJ01). Mass excesses of 46.56 and 46.40 MeV have been estimated from two different mass formulae (2000PO32). 9N would then be proton unbound by ~ 4 MeV. However, mass formulae neither take into account the fact that the last occupied orbit(s) may change near the drip lines nor the fact that an extended low-l orbit leads to a lowered Coulomb energy. The suggested s-wave ground-state of 9He and a Coulomb energy estimated from the 11N ground state

  15. A=9n (1984AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4AJ01) (Not illustrated) Not observed: see (1977DE08

  16. A=9n (1988AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8AJ01) (Not illustrated) Not observed: see (1979AJ01) and (1983BE55; theor.

  17. SNOiioaroad A9U3N3

    Gasoline and Diesel Fuel Update (EIA)

    1997 Household Characteristics RSE Column Factor: Total Four Most Populated States RSE Row Factors New York California Texas Florida 0.4 1.1 1.2 1.4 1.4 Total .............................................................. 101.5 6.8 11.5 7.0 5.9 NF 1997 Household Income Category Less than $5,000 ......................................... 3.8 0.3 0.3 0.3 0.1 16.2 $5,000 to $9,999 ......................................... 9.6 0.9 1.1 0.6 0.7 14.2 $10,000 to $14,999

  18. A=8n (1988AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8AJ01) (Not illustrated) 8n has not been observed in the interaction of 700 MeV or of 400 GeV protons with uranium: see (1979AJ01). See also (1987FL1A) and (1987SIZX; theor....

  19. A=8n (1979AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    79AJ01) (Not illustrated) 8n has not been observed in the interaction of 0.7 and 400 GeV protons with uranium: the cross section is < 2.3 10-5 b (1977TU02) at 0.7 GeV and <...

  20. A=8n (1984AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4AJ01) (Not illustrated) 8n has not been observed in the interaction of 700 MeV or of 400 GeV protons with uranium: the cross section is < 2.3 10-5 b (1977TU02; 700 MeV), <...

  1. A=8n (2004TI06)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    (Not illustrated) The nucleus 8n has not been observed. Reaction products from the interaction of 700 MeV and 400 GeV protons with uranium showed no evidence of an 8n resonance:...

  2. A=8Li (2004TI06)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    p)8Li Qm 0.80079 Angular distributions have been obtained at Et 23 MeV for the proton groups to 8Li*(0, 0.98, 2.26, 6.54 0.03); cm for 8Li*(2.26, 6.54) are 35 10 and 35...

  3. A=8Li (74AJ01)

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    cross section, comparable to the geometric value, is understood in terms of the ( + t) cluster nature of 7Li (RO62C). Cross sections for this reaction have recently been...

  4. A=8Li (66LA04)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    to the geometric value, supports the hypothesis that 7Li may be described as an ( + t) cluster (RO62C). See also (AL63N, BA63O, BR63M, VA64G). 9. 7Li(d, p)8Li Qm -0.192...

  5. A=8Be (66LA04)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    BL63B, DE63H, DE63J, WE63A, DE64E). 15. 6Li(6Li, )8Be Qm 20.808 In addition to -groups to the ground and 2.9 MeV states, there is evidence for a cluster reaction...

  6. A=8Be (74AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8Be*(16.63) is very low: 5% compared to 8Be*(16.91) as expected by predictions of the cluster model (MA66B: Ep 40.8 MeV). See also (KU67C) and reaction 21 in 9Be in (66LA04)....

  7. A=8B (1974AJ01)

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    4AJ01) (See Energy Level Diagrams for 8B) GENERAL: See also (1966LA04) and Table 8.11 [Table of Energy Levels] (in PDF or PS). Shell model: (1966BA26, 1973HA49). Special levels: (1966BA26). Electromagnetic transitions: (1966BA26, 1973HA49). Special reactions: (1968BA1M, 1968BH1A, 1969BA1L, 1970BA44, 1972AG01). Astrophysical questions: (1967BA1J, 1967SH1F, 1968BA2E, 1968BA2F, 1969FO1D, 1970BA1M, 1972PA1C). Other topics: (1966KE16, 1966TO04, 1967DI1B, 1969GA1G, 1972AN05, 1973RO1R). Ground-state

  8. A=8B (1979AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    9AJ01) (See Energy Level Diagrams for 8B) GENERAL: See also (1974AJ01) and Table 8.11 [Table of Energy Levels] (in PDF or PS). Nuclear models: (1975KH1A). Special states: (1974IR04, 1976IR1B, 1978KH03). Electromagnetic interactions: (1974KU06, 1976KU07). Special reactions: (1974BA70, 1976BE1K, 1976WE09, 1977WE1B, 1977YA1B). Pion and kaon reactions: (1973CA1C, 1977JU1B). Astrophysical questions: (1973BA1H, 1973DE1D, 1973TR1C, 1974DA18, 1976BA1J, 1977BA1V, 1977SC1D). Other topics: (1974IR04,

  9. A=8B (1984AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4AJ01) (See Energy Level Diagrams for 8B) GENERAL: See also (1979AJ01) and Table 8.11 [Table of Energy Levels] (in PDF or PS). Special states: (1980OK01). Complex reactions involving 8B (The reactions 6Li(6Li, 4H)8B, 12C(6Li, 10Be)8B, 9Be(7Li, 8He)8B and 12C(7Li, 11Be)8B have been studied at E(6Li) = 72 MeV and E(7Li) = 83 MeV (1982AL08): see 8He, 10Be, as well as 11Be in (1985AJ01).): (1979BO22, 1980GR10, 1981MO20). Astrophysical questions: (1981BA17, 1983LI01). Reactions involving pions: (

  10. A=8B (1988AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8AJ01) (See Energy Level Diagrams for 8B) GENERAL: See also (1984AJ01) and Table 8.9 [Table of Energy Levels] (in PDF or PS) here. Model calculations: (1983SH38). Special states: (1982PO12, 1988KH03). Complex reactions involving 8B: (1982AL08, 1983OL1A, 1984GR08, 1986HA1B, 1987TAZU, 1988AR05, 1988KI05). Astrophysical questions: (1984HA1B, 1985BO1E, 1985GI1C, 1985KL1A, 1985LA1C, 1988BA86). Reactions involving pions: (1983SP06). Hypernuclei: (1983SH38). Other topics: (1985AN28). Ground state of

  11. A=8B (2004TI06)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2004TI06) (See Energy Level Diagrams for 8B) GENERAL: References to articles on general properties of 8B published since the previous review (1988AJ01) are grouped into categories and listed, along with brief descriptions of each item, in the General Tables for 8B located on our website at (www.tunl.duke.edu/nucldata/General_Tables/8b.shtml). See also Table Prev. Table 8.15 preview 8.15 [Table of Energy Levels] (in PDF or PS). μ = 1.0355 ± 0.0003 μN: see (1996FIZY). Q = 68.3 ± 2.1 mb

  12. A=8B (59AJ76)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8B (59AJ76) (See the Energy Level Diagram for 8B) GENERAL: See also Table 8.10 [Table of Energy Levels] (in PDF or PS). Mass of 8B: The mass excess of 8B is 25.287 ± 0.008 MeV, from the threshold energy of the 6Li(3He, n)8B reaction. 1. 8B(β+)8Be Qm = 17.978 Q0 = 17.91 ± 0.12 MeV (VE58A). The half-life of 8B is 0.78 ± 0.01 sec (DU58), 0.61 ± 0.11 sec (SH52), 0.65 ± 0.1 sec (AL50G), 0.75 ± 0.02 sec (VE58A). The decay proceeds mainly to the 2.9-MeV state of 8Be, log ft = 5.72 (VE58A). See

  13. A=8Be (1979AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    9AJ01) (See Energy Level Diagrams for 8Be) GENERAL: See also (1974AJ01) and Table 8.3 [Table of Energy Levels] (in PDF or PS). Shell model: (1973AR1C, 1974KA11, 1975GO07, 1975SC1K, 1976AR07, 1976JI1A, 1976ST04). Collective, rotational and deformed models: (1974BO25, 1974LE04, 1975AR28, 1975KH1A). Cluster and α-particle models: (1970YU02, 1973AB1A, 1973AR1C, 1974CH01, 1974DR05, 1974KA11, 1975AB1E, 1975SC1K, 1976BA1N, 1976ST04, 1977AR08, 1977BE50, 1977FU1D, 1977FU1F, 1977HE10, 1977HE1C, 1977KA1K,

  14. A=8Be (1984AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4AJ01) (See Energy Level Diagrams for 8Be) GENERAL: See also (1979AJ01) and Table 8.4 [Table of Energy Levels] (in PDF or PS). Shell model: (1978RA1B, 1979EL04, 1981BO1Y, 1981RA06, 1981ST22, 1982FI13). Collective, rotational and deformed models: (1978CA1D, 1979EL04, 1979MA1J, 1980FI09, 1981RA06, 1981ST22, 1982FI13). Cluster and α-particle models: (1977WU1A, 1979GO24, 1979GR1F, 1979PA22, 1979ZH1C, 1980FU1G, 1980HA1M, 1980IK1B, 1981GA1J, 1981KA1P, 1981KN12, 1981KR1J, 1981ST22, 1982HA1M, 1982TS1A,

  15. A=8Be (1988AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8AJ01) (See Energy Level Diagrams for 8Be) GENERAL: See also (1984AJ01) and Table 8.4 [Table of Energy Levels] (in PDF or PS) here. Shell model: (1984PA04, 1984VA06, 1984ZW1A, 1985FI1E, 1987BL18, 1987KI1C, 1988WO04). Collective, rotational and deformed models: (1984PA04, 1985RO1G). Cluster and α-particle models: (1981PL1A, 1983CA12, 1983DR09, 1983FU1D, 1983HA41, 1983JA09, 1983SH38, 1984DE24, 1984DU17, 1984LU1A, 1984LU1B, 1985FI1E, 1986GU1F, 1986KR12, 1986SU06, 1988KR01). Special states:

  16. A=8Be (2004TI06)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2004TI06) (See Energy Level Diagrams for 8Be) GENERAL: References to articles on general properties of 8Be published since the previous review (1988AJ01) are grouped into categories and listed, along with brief descriptions of each item, in the General Tables for 8Be located on our website at (www.tunl.duke.edu/nucldata/General_Tables/8be.shtml). See also Table Prev. Table 8.9 preview 8.9 [Table of Energy Levels] (in PDF or PS). 1. 8Be → 4He4He Qm = 0.0918 Γcm for 8Beg.s. = 5.57 ± 0.25 eV:

  17. A=8C (1974AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4AJ01) (Not illustrated) 8C has been observed in the 12C(α, 8He)8C reaction at Eα = 156 MeV: M - A = 35.30 ± 0.20 MeV, Γc.m. = 220+80-140 keV [the differential cross section at 2° (lab) is ≈ 20 nb/sr] (R.G.H. Robertson, S. Martin, W.R. Falk, D. Ingham and A. Djaloeis, private communication). 8C is then unstable with respect to 7B + p (Q = 0.1), 6Be + 2p (Q = 2.3), 5Li + 3p (Q = 1.8), 4He + 4p (Q = 3.7). See also (1960GO1B, 1966KE16, 1970WA1G).

  18. A=8C (1979AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    9AJ01) (See the Isobar Diagram for 8C) Mass of 8C: The atomic mass excess of 8C is 35096 ± 26 keV, Γc.m. = 230 ± 50 keV: see (1977TR07). See also (1974AJ01, 1974RO17, 1976TR1B, 1978RO01). 8C is stable with respect to 7B + p (Q = -0.13 MeV) and unstable with respect to 6Be + 2p (Q = 2.143), 5Li + 3p (Q = 1.55), 4He + 4p (Q = 3.514). At E(3He) = 76 MeV the differential cross section for formation of 8Cg.s. in the 14N(3He, 9Li) reaction is ≈ 5 nb/sr at θlab = 10° (1976RO04). The 12C(α,

  19. A=8C (1984AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4AJ01) (See the Isobar Diagram for 8C) Mass of 8C: The atomic mass excess of 8C is 35095 ± 23 keV (A.H. Wapstra, private communication). Γc.m. = 230 ± 50 keV: see (1979AJ01). 8C is stable with respect to 7B + p (Q = -0.13 MeV) and unstable with respect to 6Be + 2p (Q = 2.14), 5Li + 3p (Q = 1.55), 4He + 4p (Q = 3.51). At E(3He) = 76 MeV the differential cross section for formation of 8Cg.s. in the 14N(3He, 9Li) reaction is ~ 5 nb/sr at θlab = 10°. The 12C(α, 8He)8C reaction has been studied

  20. A=8C (1988AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8AJ01) (See the Isobar Diagram for 8C) Mass of 8C:The atomic mass excess of 8C is 35095 ± 24 keV (1985WA02); αc.m. = 230 ± 50 keV: see (1979AJ01). 8C is stable with respect to 7B + p (Q = -0.13 MeV) and unstable with respect to 6Be + 2p (Q = 21.4), 5Li + 3p (Q = 1.55), 4He + 4p (Q = 3.51). At E(3He) = 76 MeV the differential cross section for formation of 8Cg.s. in the 14N(3He, 9Li) reaction is ~ 5 nb/sr at θlab = 10°. The 12C(α, 8He)8C reaction has been studied at Eα = 156 MeV: dσ/dΩ ~

  1. A=8C (2004TI06)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2004TI06) (See the Isobar Diagram for 8C) Mass of 8C: The atomic mass excess of 8C is 35094 ± 23 keV (2003AU03); Γcm = 230 ± 50 keV [Jπ = 0+; T = 2]: see (1979AJ01). 8C is stable with respect to 7B + p (Q = -0.07 MeV) and unstable with respect to 6Be + 2p (Q = 2.14), 5Li + 3p (Q = 1.55) and 4He + 4p (Q = 3.51). At E(3He) = 76 MeV the differential cross section for formation of 8Cg.s. in the 14N(3He, 9Li) reaction is ~ 5 nb/sr at θlab = 10°. The 12C(α, 8He)8C reaction has been studied at

  2. A=8He (1974AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4AJ01) (See the Isobar Diagram for 8He) GENERAL: See also (1966LA04). Theoretical and review papers: (1969KR20, 1969SO08, 1970KR1G, 1970RY04, 1971LO13, 1971RY1A, 1971DO1F, 1972PN1A, 1972ST1C). Experimental papers: (1966DE14, 1966PO09, 1967CO1K, 1967PO1D, 1968BA48, 1968BH1A, 1970CA1M, 1971CA47, 1972CA38, 1972VO06, 1973JU2A, 1973KO1D). Mass of 8He: The atomic mass excess of 8He derived from the Q of the 26Mg(α, 8He)22Mg reaction is 31.65 ± 0.12 MeV. See also (1968BA48). 8He is then stable to

  3. A=8He (1979AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    9AJ01) (See the Isobar Diagram for 8He) GENERAL: See also (1974AJ01). See (1973AL1B, 1973TO16, 1974IR04, 1974MA1E, 1975AB1D, 1975BE31, 1976BE1G, 1976IR1B, 1976VA29, 1978KO1H, 1978NA07). Mass of 8He: The atomic mass excess of 8He is 31596 ± 7 keV (1977TR07). See also (1974CE05, 1975JA10, 1975KO18, 1978RO01). 8He is then stable with respect to decay into 6He + 2n by 2.141 MeV. See also (1974AJ01, 1976TR1B) and (1975JE02; theor.). The IMME coefficients based on the latest masses of the T = 2

  4. A=8He (1984AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4AJ01) (See the Isobar Diagram for 8He) GENERAL: See also (1979AJ01) and Table 8.1 [Table of Energy Levels] (in PDF or PS). Complex reactions involving 8He (See (1979AJ01) for comments on the 18O(α, 8He) and 26Mg(α, 8He) reactions.): (1978VO10, 1978MA1D, 1979BE60, 1979BO22, 1980BO31, 1981BO1X, 1981SE1B, 1982BO35, 1982BO1Y, 1982GU1H, 1982OG02). Hypernuclei: (1978PO1A, 1978SO1A, 1981WA1J). Other topics: (1979BE1H, 1981AV02, 1982NG01). Mass of 8He: A study of the 64Ni(α, 8He)60Ni reaction leads

  5. A=8He (1988AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8AJ01) (See the Isobar Diagram for 8He) GENERAL: See also (1984AJ01) and Table 8.1 [Table of Energy Levels] (in PDF or PS). Model calculations: (1984VA06, 1985PO10, 1987BL18). Complex reactions involving 8He: (1982AL33, 1983AN13, 1985MA13, 1985TA1D, 1986SA30, 1987AR1G, 1987BO40, 1987KO1Z, 1987PE1C, 1987TAZU, 1988GA10, 1988ST06, 1988TA1A). Hypernuclei: (1982KA1D, 1983DO1B, 1984BO1H, 1985AH1A, 1985IK1A, 1986BA1W, 1986DA1B, 1987MI38, 1987PO1H). Other topics: (1983GL1B, 1985AN28, 1987AJ1A,

  6. A=8He (2004TI06)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2004TI06) (See Energy Level Diagrams for 8He) GENERAL: References to articles on general properties of 8He published since the previous review (1988AJ01) are grouped into categories and listed, along with brief descriptions of each item, in the General Tables for 8He located on our website at (www.tunl.duke.edu/nucldata/General_Tables/8he.shtml). See also Table Prev. Table 8.1 preview 8.1 [Table of Energy Levels] (in PDF or PS). Mass of 8He: The atomic mass excess of 8He adopted by us and by

  7. A=8He (66LA04)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8He (66LA04) (Not illustrated) GENERAL: See (GO60P, ZE60A, BA61F, LO61C, YA61B, GO64, BA65M). Mass of 8He: From the systematics of neutron binding energies (GO60O) and from the calculated mass excess of 7He, the mass excess of 8He is estimated as 31.6 to 32.4 MeV. It is thus stable against 6He + 2n by 1.3 to 2.1 MeV and should exhibit β--decay to 8Li*(0.98) with Eβ(max) = 9.7 to 10.5 MeV (DE65F). 1. 8He(β-)8Li* Qm ~ 10 An activity with half-life 30 ± 20 msec, Eβ(max) = 13 ± 2 MeV,

  8. A=8Li (1979AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    9AJ01) (See Energy Level Diagrams for 8Li) GENERAL: See also (1974AJ01) and Table 8.1 [Table of Energy Levels] (in PDF or PS). Nuclear models: (1975KH1A, 1977ST24). Special states: (1974IR04, 1976IR1B, 1978KH03). Electromagnetic interactions: (1974KU06, 1976KU07). Special reactions: (1973SI38, 1974BA70, 1974BA1N, 1974BO08, 1975FE1A, 1975ZE01, 1976BE67, 1976BO08, 1976BU16, 1977FE1B, 1977PR05, 1977ST1J, 1977YA1B, 1978DI04). Muon and neutrino interactions: (1977BA1P). Pion and kaon reactions (See

  9. A=8Li (1984AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4AJ01) (See Energy Level Diagrams for 8Li) GENERAL: See also (1979AJ01) and Table 8.2 [Table of Energy Levels] (in PDF or PS). Special states: (1980OK01). Complex reactions involving 8Li: (1978BO1B, 1978DU1B, 1979BO22, 1979IV1A, 1980AN1T, 1980BO31, 1980GR10, 1980WI1L, 1981BO1X, 1981MO20, 1982BO35, 1982BO1Y, 1982GO1E, 1982GU1H, 1982MO1N). Muon and neutrino interactions: (1978BA1G). Reactions involving pions and other mesons: (1977VE1C, 1979BA16, 1980HA29, 1981JU1A, 1981NI03, 1982HA57).

  10. A=8Li (1988AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8AJ01) (See Energy Level Diagrams for 8Li) GENERAL: See also (1984AJ01) and Table 8.2 [Table of Energy Levels] (in PDF or PS) here. Nuclear models: (1983KU17, 1983SH38, 1984MO1H, 1984REZZ, 1984VA06, 1988WO04). Special states: (1982PO12, 1983KU17, 1984REZZ, 1984VA06, 1986XU02). Electromagnetic transitions: (1983KU17). Astrophysics: (1987MA2C). Complex reactions involving 8Li: (1983FR1A, 1983GU1A, 1983OL1A, 1983WI1A, 1984GR08, 1984HI1A, 1984LA27, 1985JA1B, 1985MA02, 1985MA13, 1985MO17, 1986AV1B,

  11. A=8N (1984AJ01)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    N (1984AJ01) (Not illustrated) Not observed: see (1982NG01; theor.).

  12. A=8Be (59AJ76)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    is no indication of other S-states below Ex 11.5 MeV (NI58). The d-wave phase shift first becomes appreciable near E 2.5 MeV (HE56B) and appears to pass through resonance...

  13. A=8Li (59AJ76)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    one event corresponding to the transition to an excited state at 0.7 0.2 MeV. 3. 7Li(n, )8Li Qm 2.035 The thermal capture cross section is 33 5 mb (HU47A), 42 10 mb...

  14. Wave-Energy/-Device Modeling: Developing A 1:17 Scaled Model

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... News & Events, Renewable Energy, Research & Capabilities, Systems Analysis, Water PowerWave-Energy-Device Modeling: Developing A 1:17 Scaled Model Wave-Energy-Device Modeling: ...

  15. Table A1. Refiner/Reseller Motor Gasoline Prices by Grade, PAD...

    U.S. Energy Information Administration (EIA) Indexed Site

    Information Administration Petroleum Marketing Annual 1995 Table A1. RefinerReseller Motor Gasoline Prices by Grade, PAD District and State, 1984-Present (Cents per Gallon...

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    U.S. Energy Information Administration (EIA) Indexed Site

    AdministrationPetroleum Marketing Annual 1999 401 Table A1. RefinerReseller Motor Gasoline Prices by Grade, PAD District and State, 1984-Present (Cents per Gallon...

  17. ,"Table 3A.1. January Monthly Peak Hour Demand, by North American...

    U.S. Energy Information Administration (EIA) Indexed Site

    A.1. January Monthly Peak Hour Demand, by North American Electric Reliability Corporation ... February Monthly Peak Hour Demand, by North American Electric Reliability Corporation ...

  18. CX-008447: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    The Shift for Good Community Program (Switch 4 Good) CX(s) Applied: A1, A8, A9, A11 Date: 06/21/2012 Location(s): Multiple Offices(s): National Energy Technology Laboratory

  19. CX-012286: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    Marine Vibrator Prototype Demonstration Test CX(s) Applied: A1, A8, A9, A11, B3.11 Date: 06/12/2014 Location(s): CX: none Offices(s): National Energy Technology Laboratory

  20. Microsoft PowerPoint - 10_ROSE_MARTYN_UPDATED_NMMSS_2014_Foreign...

    National Nuclear Security Administration (NNSA)

    88 JAPAN 35 89 PEOPLES' REPUBLIC OF CHINA 37 A8 SWITZERLAND 38 A1 ARGENTINA ... LES CENTRIFUGE ENRICHMENT 76 B7 CHINAJAPAN LES CENTRIFUGE ENRICHMENT 77 A9 ...

  1. Microsoft Word - Foreign Obligation Codes.docx

    National Nuclear Security Administration (NNSA)

    34 88 Japan 35 89 Peoples' Republic of China 36 C1 Russia 37 A8 Switzerland 38 A1 ...JapanLes Centrifuge Enrichment 76 B7 ChinaJapanLes Centrifuge Enrichment 77 A9 ...

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    National Nuclear Security Administration (NNSA)

    88 JAPAN 35 89 PEOPLES' REPUBLIC OF CHINA 37 A8 SWITZERLAND 38 A1 ARGENTINA ... LES CENTRIFUGE ENRICHMENT 76 B7 CHINAJAPAN LES CENTRIFUGE ENRICHMENT 77 A9 ...

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    National Nuclear Security Administration (NNSA)

    88 JAPAN 35 89 PEOPLES' REPUBLIC OF CHINA 37 A8 SWITZERLAND 38 A1 ARGENTINA ... LES CENTRIFUGE ENRICHMENT 76 B7 CHINAJAPAN LES CENTRIFUGE ENRICHMENT 77 A9 ...

  4. CX-012272: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    Multiscale Modeling of Carbon Dioxide Migration and Trapping in Fractured Reservoirs with Validation CX(s) Applied: A1, A8, A9 Date: 06/25/2014 Location(s): New Jersey Offices(s): National Energy Technology Laboratory

  5. Axial resonances a$$_{1}$$(1260), b$$_{1}$$(1235) and their decays from the lattice

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Lang, C. B.; Leskovec, Luka; Mohler, Daniel; Prelovsek, Sasa

    2014-04-28

    The light axial-vector resonancesmore » $a_1(1260)$ and $b_1(1235)$ are explored in Nf=2 lattice QCD by simulating the corresponding scattering channels $$\\rho\\pi$$ and $$\\omega\\pi$$. Interpolating fields $$\\bar{q} q$$ and $$\\rho\\pi$$ or $$\\omega\\pi$$ are used to extract the s-wave phase shifts for the first time. The $$\\rho$$ and $$\\omega$$ are treated as stable and we argue that this is justified in the considered energy range and for our parameters $$m_\\pi\\simeq 266~$$MeV and $$L\\simeq 2~$$fm. We neglect other channels that would be open when using physical masses in continuum. Assuming a resonance interpretation a Breit-Wigner fit to the phase shift gives the $a_1(1260)$ resonance mass $$m_{a1}^{res}=1.435(53)(^{+0}_{-109})$$ GeV compared to $$m_{a1}^{exp}=1.230(40)$$ GeV. The $a_1$ width $$\\Gamma_{a1}(s)=g^2 p/s$$ is parametrized in terms of the coupling and we obtain $$g_{a_1\\rho\\pi}=1.71(39)$$ GeV compared to $$g_{a_1\\rho\\pi}^{exp}=1.35(30)$$ GeV derived from $$\\Gamma_{a1}^{exp}=425(175)$$ MeV. In the $b_1$ channel, we find energy levels related to $$\\pi(0)\\omega(0)$$ and $b_1(1235)$, and the lowest level is found at $$E_1 \\gtrsim m_\\omega+m_\\pi$$ but is within uncertainty also compatible with an attractive interaction. Lastly, assuming the coupling $$g_{b_1\\omega\\pi}$$ extracted from the experimental width we estimate $$m_{b_1}^{res}=1.414(36)(^{+0}_{-83})$$.« less

  6. A 1.3-Å Structure of Zinc-bound N-terminal Domain of Calmodulin...

    Office of Scientific and Technical Information (OSTI)

    Ion-binding Step Citation Details In-Document Search Title: A 1.3- Structure of Zinc-bound N-terminal Domain of Calmodulin Elucidates Potential Early Ion-binding Step Authors: ...

  7. Induction of cytochromes P450 1A1 and 1A2 by tanshinones in human...

    Office of Scientific and Technical Information (OSTI)

    human HepG2 hepatoma cell line Citation Details In-Document Search Title: Induction of cytochromes P450 1A1 and 1A2 by tanshinones in human HepG2 hepatoma cell line Diterpenoid ...

  8. File:FormA1-R.pdf | Open Energy Information

    Open Energy Info (EERE)

    link to this file. Retrieved from "http:en.openei.orgwindex.php?titleFile:FormA1-R.pdf&oldid532769" Feedback Contact needs updating Image needs updating Reference...

  9. Refrigerators and Refrigerator-Freezers (Appendix A1 after May 2, 2011) |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Refrigerators and Refrigerator-Freezers (Appendix A1 after May 2, 2011) Refrigerators and Refrigerator-Freezers (Appendix A1 after May 2, 2011) The Department of Energy (DOE) develops standardized data templates for reporting the results of tests conducted in accordance with current DOE test procedures. Templates may be used by third-party laboratories under contract with DOE that conduct testing in support of ENERGY STAR® verification, DOE rulemakings, and enforcement

  10. Table A1. Refiner/Reseller Motor Gasoline Prices by Grade, PAD...

    U.S. Energy Information Administration (EIA) Indexed Site

    71.6 92.3 78.2 101.8 83.6 87.5 74.7 See footnotes at end of table. A1. RefinerReseller Motor Gasoline Prices by Grade, PAD District, and State, 1984-Present 452 Energy Information...

  11. Higgs Coupling Measurements at a 1 TeV Linear Collider

    SciTech Connect (OSTI)

    Barklow, T

    2003-12-18

    Methods for extracting Higgs boson signals at a 1 TeV center-of-mass energy e{sup +}e{sup -} linear collider are described. In addition, estimates are given for the accuracy with which branching fractions can be measured for Higgs boson decays to b{bar b} WW, gg, and {gamma}{gamma}.

  12. Carbon Dioxide, Hydrographic, and Chemical Data Obtained During the R/V Meteor Cruise 28/1 in the South Atlantic Ocean (WOCE Section A8, March 29 - May 12, 1994)

    SciTech Connect (OSTI)

    Kozyr, A.

    2002-05-09

    This data documentation discusses the procedures and methods used to measure total carbon dioxide (TCO{sub 2}) and the fugacity of CO{sub 2} (fCO{sub 2}) at hydrographic stations during the R/V Meteor oceanographic cruise 28/1 in the South Atlantic Ocean (Section A8). Conducted as part of the World Ocean Circulation Experiment (WOCE), the cruise began in Recife, Brazil, on March 29, 1994, and ended after 35 days at sea in Walvis Bay, Namibia, on May 12, 1994. Instructions for accessing the data are provided. TCO{sub 2} was measured using two single-operator multiparameter metabolic analyzers (SOMMA) coupled to a coulometer for extracting and detecting CO{sub 2} from seawater samples. The overall precision and accuracy of the analyses was {+-}1.17 {micro}mol/kg. For the second carbonate system parameter, the fCO{sub 2} was measured in discrete samples by equilibrating a known volume of liquid phase (seawater) with a known volume of a gas phase containing a known mixture of CO{sub 2} in gaseous nitrogen (N{sub 2}). After equilibration, the gas phase CO{sub 2} concentration was determined by flame ionization detection following the catalytic conversion of CO{sub 2} to methane (CH{sub 4}). The precision of these measurements was less than or equal to 1.0%. The R/V Meteor Cruise 28/1 data set is available free of charge as a numeric data package (NDP) from the Carbon Dioxide Information Analysis Center. The NDP consists of two oceanographic data files, two FORTRAN 90 data retrieval routine files, a readme file, and this printed documentation that describes the contents and format of all files as well as the procedures and methods used to obtain the data.

  13. Predicting the future could win a $1,000 California or Illinois scholarship

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Predicting The Future Could Win California Or Illinois Scholarship Community Connections: Your link to news and opportunities from Los Alamos National Laboratory Latest Issue: September 1, 2016 all issues All Issues » submit Predicting the future could win a $1,000 California or Illinois scholarship To qualify, students need to post the answer to this question on their blog or website: "Where do you see the Internet in 10 years?" September 1, 2012 dummy image Read our archives

  14. Neutron dosimetry and damage calculations for the ATR-A1 irradiation

    SciTech Connect (OSTI)

    Greenwood, L.R.; Ratner, R.T.

    1998-09-01

    Neutron fluence measurements and radiation damage calculations are reported for the collaborative US/Japan ATR-A1 irradiation in the Advanced Test Reactor (ATR) at Idaho National Engineering Laboratory (INEL). The maximum total neutron fluence at midplane was 9.4 {times} 10{sup 21} n/cm{sup 2} (5.5 {times} 10{sup 21} n/cm{sup 2} above 0.1 MeV), resulting in about 4.6 dpa in vanadium.

  15. Active site proton delivery and the lyase activity of human CYP17A1

    SciTech Connect (OSTI)

    Khatri, Yogan; Gregory, Michael C.; Grinkova, Yelena V.; Denisov, Ilia G.; Sligar, Stephen G.

    2014-01-03

    Highlights: The disruption of PREG/PROG hydroxylation activity by T306A showed the participation of Cpd I. T306A supports the involvement of a nucleophilic peroxo-anion during lyase activity. The presence of cytochrome b{sub 5} augments CC lyase activity. ?5-Steroids are preferred substrates for CYP17 catalysis. -- Abstract: Cytochrome P450 CYP17A1 catalyzes a series of reactions that lie at the intersection of corticoid and androgen biosynthesis and thus occupies an essential role in steroid hormone metabolism. This multifunctional enzyme catalyzes the 17?-hydroxylation of ?4- and ?5-steroids progesterone and pregnenolone to form the corresponding 17?-hydroxy products through its hydroxylase activity, and a subsequent 17,20-carboncarbon scission of pregnene-side chain produce the androgens androstenedione (AD) and dehydroepiandrosterone (DHEA). While the former hydroxylation reaction is believed to proceed through a conventional Compound I rebound mechanism, it has been suggested that the latter carbon cleavage is initiated by an iron-peroxy intermediate. We report on the role of Thr306 in CYP17 catalysis. Thr306 is a member of the conserved acid/alcohol pair thought to be essential for the efficient delivery of protons required for hydroperoxoanion heterolysis and formation of Compound I in the cytochromes P450. Wild type and T306A CYP17A1 self-assembled in Nanodiscs were used to quantitate turnover and coupling efficiencies of CYP17s physiological ?4- and ?5-substrates. We observed that T306A co-incorporated in Nanodiscs with its redox partner cytochrome P450 oxidoreductase, coupled NADPH only by 0.9% and 0.7% compared to the wild type (97% and 22%) during the conversion of pregnenolone and progesterone, respectively, to the corresponding 17-OH products. Despite increased oxidation of pyridine nucleotide, hydroxylase activity was drastically diminished in the T306A mutant, suggesting a high degree of uncoupling in which reducing equivalents and protons

  16. Measurement of velocity deficit at the downstream of a 1:10 axial hydrokinetic turbine model

    SciTech Connect (OSTI)

    Gunawan, Budi; Neary, Vincent S; Hill, Craig; Chamorro, Leonardo

    2012-01-01

    Wake recovery constrains the downstream spacing and density of turbines that can be deployed in turbine farms and limits the amount of energy that can be produced at a hydrokinetic energy site. This study investigates the wake recovery at the downstream of a 1:10 axial flow turbine model using a pulse-to-pulse coherent Acoustic Doppler Profiler (ADP). In addition, turbine inflow and outflow velocities were measured for calculating the thrust on the turbine. The result shows that the depth-averaged longitudinal velocity recovers to 97% of the inflow velocity at 35 turbine diameter (D) downstream of the turbine.

  17. Overview of Remote Handling Equipment Used for the NPP A1 Decommissioning - 12141

    SciTech Connect (OSTI)

    Kravarik, K.; Medved, J.; Pekar, A.; Stubna, M.; Michal, V.; Vargovcik, L.

    2012-07-01

    The first Czechoslovak NPP A1 was in operation from 1972 to 1977 and it was finally shutdown due to an accident (level 4 according to the INES). The presence of radioactive, toxic or hazardous materials limits personnel access to facilities and therefore it is necessary to use remote handling technologies for some most difficult characterization, retrieval, decontamination and dismantling tasks. The history of remote handling technologies utilization started in nineties when the spent nuclear fuel, including those fuel assemblies damaged during the accident, was prepared for the transport to Russia. Subsequent significant development of remote handling equipment continued during implementation of the NPP A1 decommissioning project - Stage I and ongoing Stage II. Company VUJE, Inc. is the general contractor for both mentioned stages of the decommissioning project. Various remote handling manipulators and robotics arms were developed and used. It includes remotely controlled vehicle manipulator MT-15 used for characterisation tasks in hostile and radioactive environment, special robust manipulator DENAR-41 used for the decontamination of underground storage tanks and multi-purposes robotics arms MT-80 and MT-80A developed for variety of decontamination and dismantling tasks. The heavy water evaporator facility dismantling is the current task performed remotely by robotics arm MT-80. The heavy water evaporator is located inside the main production building in the room No. 220 where loose surface contamination varies from 10 Bq/cm{sup 2} to 1x10{sup 3} Bq/cm{sup 2}, dose rate is up to 1.5 mGy/h and the feeding pipeline contained liquid RAW with high tritium content. Presented manipulators have been designed for broad range of decommissioning tasks. They are used for recognition, sampling, waste retrieval from large underground tanks, decontamination and dismantling of technological equipments. Each of the mentioned fields claims specific requirements on design of

  18. Test of a 1.8 Tesla, 400 Hz Dipole for a Muon Synchrotron

    SciTech Connect (OSTI)

    Summers, D.J.; Cremaldi, L.M.; Hart, T.L.; Perera, L.P.; Reep, M.; Witte, H.; Hansen, S.; Lopes, M.L.; Reidy Jr., J.; /Oxford High School

    2012-05-01

    A 1.8 T dipole magnet using thin grain oriented silicon steel laminations has been constructed as a prototype for a muon synchrotron ramping at 400 Hz. Following the practice in large 3 phase transformers and our own Opera-2d simulations, joints are mitred to take advantage of the magnetic properties of the steel which are much better in the direction in which the steel was rolled. Measurements with a Hysteresigraph 5500 and Epstein frame show a high magnetic permeability which minimizes stored energy in the yoke allowing the magnet to ramp quickly with modest voltage. Coercivity is low which minimizes hysteresis losses. A power supply with a fast Insulated Gate Bipolar Transistor (IGBT) switch and a capacitor was constructed. Coils are wound with 12 gauge copper wire. Thin wire and laminations minimize eddy current losses. The magnetic field was measured with a peak sensing Hall probe.

  19. Laser photodetachment diagnostics of a 1/3-size negative hydrogen ion source for NBI

    SciTech Connect (OSTI)

    Geng, S.; Tsumori, K.; Nakano, H.; Kisaki, M.; Ikeda, K.; Takeiri, Y.; Osakabe, M.; Nagaoka, K.; Kaneko, O.

    2015-04-08

    To investigate the flows of charged particles in front of the plasma grid (PG) in a negative hydrogen ion source, the information of the local densities of electrons and negative hydrogen ions (H-) are necessary. For this purpose, the laser photodetachment is applied for pure hydrogen plasmas and Cs-seeded plasma in a 1/3-size negative hydrogen ion source in NIFS-NBI test stand. The H- density obtained by photodetachment is calibrated by the results from cavity ring-down (CRD). The pressure dependence and PG bias dependence of the local H- density are presented and discussed. The results show that H- density increases significantly by seeding Cs into the plasma. In Cs-seeded plasma, relativity exists between the H- ion density and plasma potential.

  20. Polycyclic aromatic hydrocarbon-DNA adducts and the CYP1A1 restriction fragment length polymorphism

    SciTech Connect (OSTI)

    Shields, P.G.; Bowman, E.D.; Weston, A.; Harris, C.C.; Sugimura, H.; Caporaso, N.E.; Petruzzelli, S.F. ); Trump, B.F. )

    1992-11-01

    Human cancer risk assessment at a genetic level involves the investigation of carcinogen metabolism and DNA adduct formation. Wide interindividual differences in metabolism result in different DNA adduct levels. For this and other reasons, many laboratories have considered DNA adducts to be a measure of the biologically effective dose of a carcinogen. Techniques for studying DNA adducts using chemically specific assays are becoming available. A modification of the [sup 32]P-postlabeling assay for polycyclic aromatic hydrocarbon DNA adducts described here provides potential improvements in quantification. DNA adducts, however, reflect only recent exposure to carcinogens; in contrast, genetic testing for metabolic capacity indicates the extent to which carcinogens can be activated and exert genotoxic effects. Such studies may reflect both separate and integrated risk factors together with DNA adduct levels. A recently described restriction fragment length polymorphism for the CYP1A1, which codes for the cytochrome P450 enzyme primarily responsible for the metabolic activation of carcinogenic polycyclic aromatic hydrocarbons, has been found to be associated with lung cancer risk in a Japanese population. In a subset of individuals enrolled in a US lung cancer case-control study, no association with lung cancer was found. 17 refs., 3 figs.

  1. Daymet: Daily Surface Weather Data on a 1-km Grid for North America, Version 2.

    SciTech Connect (OSTI)

    Thornton, Peter E; Thornton, Michele M; Mayer, Benjamin W; Wilhelmi, Nate; Wei, Yaxing; Devarakonda, Ranjeet; Cook, Robert B

    2014-01-01

    More information: http://daymet.ornl.gov Presenter: Ranjeet Devarakonda Environmental Sciences Division Oak Ridge National Laboratory (ORNL) Daymet: Daily Surface Weather Data and Climatological Summaries provides gridded estimates of daily weather parameters for North America, including daily continuous surfaces of minimum and maximum temperature, precipitation occurrence and amount, humidity, shortwave radiation, snow water equivalent, and day length. The current data product (Version 2) covers the period January 1, 1980 to December 31, 2013 [1]. The prior product (Version 1) only covered from 1980-2008. Data are available on a daily time step at a 1-km x 1-km spatial resolution in Lambert Conformal Conic projection with a spatial extent that covers the conterminous United States, Mexico, and Southern Canada as meteorological station density allows. Daymet data can be downloaded from 1) the ORNL Distributed Active Archive Center (DAAC) search and order tools (http://daac.ornl.gov/cgi-bin/cart/add2cart.pl?add=1219) or directly from the DAAC FTP site (http://daac.ornl.gov/cgi-bin/dsviewer.pl?ds_id=1219) and 2) the Single Pixel Tool [2] and THREDDS (Thematic Real-time Environmental Data Services) Data Server [3]. The Single Pixel Data Extraction Tool allows users to enter a single geographic point by latitude and longitude in decimal degrees. A routine is executed that translates the (lon, lat) coordinates into projected Daymet (x,y) coordinates. These coordinates are used to access the Daymet database of daily-interpolated surface weather variables. Daily data from the nearest 1 km x 1 km Daymet grid cell are extracted from the database and formatted as a table with one column for each Daymet variable and one row for each day. All daily data for selected years are returned as a single (long) table, formatted for display in the browser window. At the top of this table is a link to the same data in a simple comma-separated text format, suitable for import into a

  2. Experimental results from pressure testing a 1:6-scale nuclear power plant containment

    SciTech Connect (OSTI)

    Horschel, D.S.

    1992-01-01

    This report discusses the testing of a 1:6-scale, reinforced-concrete containment building at Sandia National Laboratories, in Albuquerque, New Mexico. The scale-model, Light Water Reactor (LWR) containment building was designed and built to the American Society of Mechanical Engineers (ASME) code by United Engineers and Constructors, Inc., and was instrumented with over 1200 transducers to prepare for the test. The containment model was tested to failure to determine its response to static internal overpressurization. As part of the US Nuclear Regulatory Commission`s program on containment integrity, the test results will be used to assess the capability of analytical methods to predict the performance of containments under severe-accident loads. The scaled dimensions of the cylindrical wall and hemispherical dome were typical of a full-size containment. Other typical features included in the heavily reinforced model were equipment hatches, personnel air locks, several small piping penetrations, and a ihin steel liner that was attached to the concrete by headed studs. In addition to the transducers attached to the model, an acoustic detection system and several video and still cameras were used during testing to gather data and to aid in the conduct of the test. The model and its instrumentation are briefly discussed, and is followed by the testing procedures and measured response of the containment model. A summary discussion is included to aid in understanding the significance of the test as it applies to real world reinforced concrete containment structures. The data gathered during SIT and overpressure testing are included as an appendix.

  3. An early look of comet C/2013 A1 (Siding Spring): Breathtaker or nightmare?

    SciTech Connect (OSTI)

    Ye, Quan-Zhi; Hui, Man-To

    2014-06-01

    The dynamically new comet, C/2013 A1 (Siding Spring), is to make a close approach to Mars on 2014 October 19 at 18:30 UT at a distance of 40 1 Martian radii. Such an extremely rare event offers a precious opportunity for the spacecrafts on Mars to closely study a dynamically new comet itself as well as the planet-comet interaction. Meanwhile, the high-speed meteoroids released from C/Siding Spring also pose a threat to physically damage the spacecrafts. Here we present our observations and modeling results of C/Siding Spring to characterize the comet and assess the risk posed to the spacecrafts on Mars. We find that the optical tail of C/Siding Spring is dominated by larger particles at the time of the observation. Synchrone simulation suggests that the comet was already active in late 2012 when it was more than 7 AU from the Sun. By parameterizing the dust activity with a semi-analytic model, we find that the ejection speed of C/Siding Spring is comparable to comets such as the target of the Rosetta mission, 67P/Churyumov-Gerasimenko. Under a nominal situation, the simulated dust cone will miss the planet by about 20 Martian radii. At the extreme ends of uncertainties, the simulated dust cone will engulf Mars, but the meteoric influx at Mars is still comparable to the nominal sporadic influx, seemly indicating that an intense and enduring meteoroid bombardment due to C/Siding Spring is unlikely. Further simulation also suggests that gravitational disruption of the dust tail may be significant enough to be observable at Earth.

  4. MNK1 expression increases during cellular senescence and modulates the subcellular localization of hnRNP A1

    SciTech Connect (OSTI)

    Ziaei, Samira; The Graduate School and University Center of CUNY, New York, NY ; Shimada, Naoko; Kucharavy, Herman; Hubbard, Karen; The Graduate School and University Center of CUNY, New York, NY

    2012-03-10

    Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is an RNA-binding protein that modulates splice site usage, polyadenylation, and cleavage efficiency. This protein has also been implicated in mRNA stability and transport from the nucleus. We have previously demonstrated that hnRNP A1 had diminished protein levels and showed cytoplasmic accumulation in senescent human diploid fibroblasts. Furthermore, we have shown that inhibition of p38 MAPK, a key regulator of cellular senescence, elevated hnRNP A1 protein levels and inhibited hnRNP A1 cytoplasmic localization. In this study, we have explored the possible involvement of MNK1, one of the downstream effector of p38 MAPK, in the regulation of hnRNP A1. We have demonstrated that pharmacological inhibition of MNK1 by CGP 57380 decreased the phosphorylation levels of hnRNP A1 in young and senescent fibroblast cells and blocked the cytoplasmic accumulation of hnRNP A1 in senescent cells. In addition, MNK1 formed a complex with hnRNP A1 in vivo. The expression levels of MNK1, phospho-MNK1, and phospho-eIF4E proteins were found to be elevated in senescent cells. These data suggest that MNK1 regulates the phosphorylation and the subcellular distribution of hnRNP A1 and that MNK1 may play a role in the induction of senescence. -- Highlights: Black-Right-Pointing-Pointer MNK1 and not MAPKAPK2 phosphorylates hnRNP A1. Black-Right-Pointing-Pointer MNK1 has elevated levels in senescent cells, this has not been reported previously. Black-Right-Pointing-Pointer MNK1 activity induces cytoplasmic accumulation of hnRNP A1 in senescent cells. Black-Right-Pointing-Pointer Altered cytoplasmic localization of hnRNP A1 may alter gene expression patterns. Black-Right-Pointing-Pointer Our studies may increase our understanding of RNA metabolism during cellular aging.

  5. Categorical Exclusion Determinations: A9 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... June 11, 2016 CX-100630 Categorical Exclusion Determination Interfacial Work Function ... May 26, 2016 CX-100621 Categorical Exclusion Determination Linear Fresnel Reflector Award ...

  6. a1.xls

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    2003 Commercial Buildings Energy Consumption Survey Detailed Tables October 2006 Energy Information Administration 2003 Commercial Buildings Energy Consumption Survey Detailed...

  7. a1.xls

    U.S. Energy Information Administration (EIA) Indexed Site

    Principal Building Activity Education ...... 7.1 6.0 ... Principal Building Activity Education ...... 7.1 15.1 ...

  8. a1.xls

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    See "Guide to the Tables" or "Glossary" for further explanations of the terms used in this table. Both can be accessed from the CBECS web site http:www.eia.doe.govemeucbecs. ...

  9. a1.xls

    Gasoline and Diesel Fuel Update (EIA)

    Both can be accessed from the CBECS web site http:www.eia.doe.govemeucbecs. Note: Due ... Both can be accessed from the CBECS web site http:www.eia.doe.govemeucbecs. QData ...

  10. Microstructural examination of V-(3-6%)Cr-(3-5%)Ti irradiated in the ATR-A1 experiment

    SciTech Connect (OSTI)

    Gelles, D.S.

    1998-09-01

    Microstructural examination results are reported for four heats of V-(3-6%)Cr-(3-5%)Ti irradiated in the ATR-A1 experiment to {approximately}4 dpa at {approximately}200 and 300 C to provide an understanding of the microstructural evolution that may be associated with degradation of mechanical properties. Fine precipitates were observed in high density intermixed with small defect clusters for all conditions examined following the irradiation. The irradiation-induced precipitation does not appear to be affected by preirradiation heat treatment or composition.

  11. Osteogenesis imperfecta type I: Molecular heterogeneity for COL1A1 null alleles of type I collagen

    SciTech Connect (OSTI)

    Willing, M.C.; Deschenes, S.P.; Pitts, S.H.; Arikat, H.; Roberts, E.J.; Scott, D.A.; Slayton, R.L.; Byers, P.H.

    1994-10-01

    Osteogenesis imperfecta (OI) type I is the mildest form of inherited brittle-bone disease. Dermal fibroblasts from most affected individuals produce about half the usual amount of type I procollagen, as a result of a COL1A1 {open_quotes}null{close_quotes} allele. Using PCR amplification of genomic DNA from affected individuals, followed by denaturing gradient gel electrophoresis (DGGE) and SSCP, we identified seven different COL1A1 gene mutations in eight unrelated families with OI type I. Three families have single nucleotide substitutions that alter 5{prime} donor splice sites; two of these unrelated families have the same mutation. One family has a point mutation, in an exon, that creates a premature termination codon, and four have small deletions or insertions, within exons, that create translational frameshifts and new termination codons downstream of the mutation sites. Each mutation leads to both marked reduction in steady-state levels of mRNA from the mutant allele and a quantitative decrease in type I procollagen production. Our data demonstrate that different molecular mechanisms that have the same effect on type I collagen production result in the same clinical phenotype. 58 refs., 4 figs., 1 tab.

  12. Deficient expression of aldehyde dehydrogenase 1A1 is consistent with increased sensitivity of Gorlin syndrome patients to radiation carcinogenesis

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Wright, Aaron T.; Magnaldo, Thierry; Sontag, Ryan L.; Anderson, Lindsey N.; Sadler, Natalie C.; Piehowski, Paul D.; Gache, Yannick; Weber, Thomas J.

    2013-11-27

    Human phenotypes that are highly susceptible to radiation carcinogenesis have been identified. Sensitive phenotypes often display robust regulation of molecular features that modify biological response, which can facilitate identification of relevant pathways/networks. Here we interrogate primary dermal fibroblasts isolated from Gorlin syndrome patients (GDFs), who display a pronounced tumorigenic response to radiation, in comparison to normal human dermal fibroblasts (NHDFs). Our approach exploits newly developed thiol-reactive probes with a flexible click chemistry functional group to define changes in protein thiol profiles in live cell studies, which minimizes artifacts associated with cell lysis. We observe qualitative differences in protein thiol profilesmore » by SDS-PAGE analysis when detection by iodoacetamide vs maleimide probe chemistries are compared, and pretreatment of cells with hydrogen peroxide eliminates detection of the majority of SDS-PAGE bands. Redox probes revealed deficient expression of an apparent 55 kDa protein thiol in GDFs from independent donors, compared with NHDFs. Proteomics tentatively identified this protein as aldehyde dehydrogenase 1A1 (ALDH1A1), a key enzyme regulating retinoic acid synthesis, and this deficiency was confirmed by Western blot. Redox probes revealed additional protein thiol differences between GDFs and NHDFs, including radiation responsive annexin family members. Our results indicate a multifactorial basis for the unusual sensitivity of Gorlin syndrome to radiation carcinogenesis, and the pathways identified have plausible implications for radiation health effects.« less

  13. Measurements of the Neutron Longitudinal Spin Asymmetry A1n and Flavor Decomposition in the Valence Quark Region

    SciTech Connect (OSTI)

    Flay, David J.

    2014-08-01

    The current data for the nucleon-virtual photon longitudinal spin asymmetry A1 on the proton and neutron have shown that the ratio of the polarized-to-unpolarized down-quarkparton distribution functions,Dd=d, tends towards -1/2 at large x, in disagreement with the perturbative QCD prediction that Dd/d approaches 1 but more in line with constituent quark models. As a part of experiment E06-014 in Hall A of Jefferson Lab, double-spin asymmetries were measured in the scattering of a longitudinally polarized electron beam of energies 4.74 and 5.89 GeV from a longitudinally and transversely polarized 3He target in the deep inelastic scattering and resonance region, allowing for the extraction of the neutron asymmetry An1 and the ratios Dd/d and Du/u. We will discuss our analysis of the data and present results for A1 and g1/F1 on both 3He and the neutron, and the resulting quark ratios for the up and down quarks in the kinematic range of 0.2

  14. Extreme Climate Event Trends: The Data Mining and Evaluation of the A1FI Scenario for 2000???2100

    SciTech Connect (OSTI)

    Erickson III, David J; Ganguly, Auroop R; Steinhaeuser, Karsten J K; Branstetter, Marcia L; Oglesby, Robert; Hoffman, Forrest M; Buja, Lawrence

    2008-01-01

    The authors discuss the implications and resulting alterations of the hydrologic cycle as Earth climate evolves from 2000-2100. Climate simulations based on the assumptions implicit in the A1F1 scenario for the period 2000-2100 using CCSM3 are analyzed. In particular, we will assess the changes in the surface latent and sensible heat energy budget, the Indian regional water budgets including trends in the timing and duration of the Indian monsoon and the resulting impacts on mean river flow and hydroelectric power generation potential. These analyses will also be examined within the context of heat index, droughts, floods and related estimates of societal robustness and resiliency. We will interpret these new A1F1 results within the context of the previous climate simulations based on the SRES A2 and B1 scenarios forced with land cover and atmospheric CO2. Analyses of historical records in the context of the Indian Monsoon Rainfall (IMR) have suggested an evolving relation of IMR with natural climate variability caused by El Nino events. We will report on the combined effects of natural climate variability and global warming on IMR and assess the trend of extreme rain and temperature events in a warming environment.

  15. Quantum lattice fluctuations in a 1-dimensional charge-density-wave material: Luminescence and resonance Raman studies

    SciTech Connect (OSTI)

    Long, F.H.; Love, S.P.; Swanson, B.I.

    1993-12-31

    Luminescence spectra, both emission and excitation, and the excitation dependence of the resonance Raman (RR) spectra have been measured for a 1-dimensional charge-density-wave solid, [Pt(L)CI{sub 2}][Pt(L)](CIO{sub 4}){sub 4}; L=1,2-diaminoethane. The luminescence experiments support the existence of tail states in the band gap region, which indicate the presence of disorder. In contrast, the RR measurements conclusively demonstrate that the effects of static structural disorder on the vibrational spectroscopy can be neglected. This apparently paradoxical result can be explained by considering the zero-point motion of the lattice. The experimental results are compared to recent theoretical models.

  16. CX-006508: Categorical Exclusion Determination

    Office of Energy Efficiency and Renewable Energy (EERE)

    Development of Large Format Lithium Ion Cells with Higher Energy Density Exceeding 500 Watthours per LiterCX(s) Applied: A1, A8, A9Date: 08/25/2011Location(s): Midland, MichiganOffice(s): Energy Efficiency and Renewable Energy, National Energy Technology Laboratory

  17. CX-003036: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    Pacific Northwest Smart Grid DemonstrationCX(s) Applied: A1, A8, A9, A11, B1.7Date: 07/13/2010Location(s): Richland, WashingtonOffice(s): Electricity Delivery and Energy Reliability, National Energy Technology Laboratory

  18. Wake of the MOD-0A1 wind turbine at two rotor diameters downwind on December 3, 1981

    SciTech Connect (OSTI)

    Connell, J.R.; George, R.L.

    1982-11-01

    The wake of the MOD-0A1 wind turbine at Clayton, New Mexico has been measured using a vertical plane array of anemometers in a crosswind plane at a distance of two rotor diameters directly downwind of the turbine. Rotor blade vortices were well mixed into the wake turbulence and were not separately detectable. Wake swirl about the along-wind axis had a value not greater than 0.025 rad/s. Extra turbulence energy existed in the edge of the wake at a frequency of about n=0.025 Hz. The cross-wake plane analyses of wind speeds revealed a nearly circular inner portion and a strongly elliptical portion. The elliptical portion major axis was horizontal. An estimate of the average rate of reenergizing of the wake, using measurements of mean wind energy flow and turbine power, suggests that entrainment with ambient air may have been rapid. Some wake characteristics were compared with the corresponding ones for several simple wake models based upon concepts of mixing of ambient air into a wake or an equivalent coaxial jet. (LEW)

  19. A method distinguishing expressed vs. null mutations of the Col1A1 gene in osteogenesis imperfecta

    SciTech Connect (OSTI)

    Redford-Badwal, D.A.; Stover, M.L.; McKinstry, M.

    1994-09-01

    Osteogenesis imperfecta (OI) is a heterogeneous group of heritable disorders of bone characterized by increased susceptibility to fracture. Most of the causative mutations were identified in patients with the lethal form of the disease. Attention is now shifting to the milder forms of OI where glycine substitutions and null producing mutations have been found. Single amino acid substitutions can be identified by RT/PCR of total cellular RNA, but this approach does not work well for null mutations since the defective transcript does not accumulate in the cytoplasm. We have altered our RNA extraction method to separate RNA from the nuclear and cytoplasmic compartments of cultured fibroblasts. Standard methods of mutation identification (RT/PCR followed by SSCP) is applied to each RNA fraction. DNA from an abnormal band on the SSCP gel is eluted and amplified by PCR for cloning and sequencing. Using this approach we have identified an Asp to Asn change in exon 50 (type II OI) and a Gly to Arg in exon 11 (type I OI) of the COL1A1 gene. These changes were found in both nuclear and cytoplasmic compartments. These putative mutations are currently being confirmed by protein studies. In contrast, three patients with mild OI associated with reduced {proportional_to}(I)mRNA, had distinguishing SSCP bands present in the nuclear but not the cytoplasmic compartment. In one case a frame shift mutation was observed, while the other two revealed polymorphisms. The compartmentalization of the mutant allele has directed us to look elsewhere in the transcript for the causative mutation. This approach to mutation identification is capable of distinguishing these fundamentally different types of mutations and allows for preferential cloning and sequencing of the abnormal allele.

  20. Thermal regulation of tightly packed solid-state photodetectors in a 1 mm{sup 3} resolution clinical PET system

    SciTech Connect (OSTI)

    Freese, D. L.; Vandenbroucke, A.; Innes, D.; Lau, F. W. Y.; Hsu, D. F. C.; Reynolds, P. D.; Levin, Craig S.

    2015-01-15

    Purpose: Silicon photodetectors are of significant interest for use in positron emission tomography (PET) systems due to their compact size, insensitivity to magnetic fields, and high quantum efficiency. However, one of their main disadvantages is fluctuations in temperature cause strong shifts in gain of the devices. PET system designs with high photodetector density suffer both increased thermal density and constrained options for thermally regulating the devices. This paper proposes a method of thermally regulating densely packed silicon photodetectors in the context of a 1 mm{sup 3} resolution, high-sensitivity PET camera dedicated to breast imaging. Methods: The PET camera under construction consists of 2304 units, each containing two 8 × 8 arrays of 1 mm{sup 3} LYSO crystals coupled to two position sensitive avalanche photodiodes (PSAPD). A subsection of the proposed camera with 512 PSAPDs has been constructed. The proposed thermal regulation design uses water-cooled heat sinks, thermoelectric elements, and thermistors to measure and regulate the temperature of the PSAPDs in a novel manner. Active cooling elements, placed at the edge of the detector stack due to limited access, are controlled based on collective leakage current and temperature measurements in order to keep all the PSAPDs at a consistent temperature. This thermal regulation design is characterized for the temperature profile across the camera and for the time required for cooling changes to propagate across the camera. These properties guide the implementation of a software-based, cascaded proportional-integral-derivative control loop that controls the current through the Peltier elements by monitoring thermistor temperature and leakage current. The stability of leakage current, temperature within the system using this control loop is tested over a period of 14 h. The energy resolution is then measured over a period of 8.66 h. Finally, the consistency of PSAPD gain between independent

  1. Data:00cdded9-47a1-49b6-a217-10941ffbefc6 | Open Energy Information

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  6. Structure of a CutA1 divalent-cation tolerance protein from Cryptosporidium parvum, the protozoal parasite responsible for cryptosporidiosis

    SciTech Connect (OSTI)

    Buchko, Garry W.; Robinson, Howard; Abendroth, Jan; Clitfon, Mathew C.; Zhang, Yanfeng; Hewitt, Stephen N.; Staker, Bart L.; Van Voorhis, Wesley C.; Mylera, Peter J.

    2015-05-01

    Cryptosporidiosis is an infectious disease caused by protozoan parasites from the Cryptosporidium species. Infection is associated with mild to severe diarrhea that usually resolves spontaneously in healthy human adults, but may lead to severe complications in young children and in immunocompromised patients. The genome of Cryptosporidium parvum contains a gene, CUTA_CRYPI, that may play a role in regulating the intracellular concentration of copper, a toxic element if left unchecked. Here we report the crystal structure for this CutA1 protein, Cp-CutA1, is reported at 2.0 resolution (4E98). As observed for other CutA1 structures, the 117-residue protein is a trimer with a core ferrodoxin-like fold. Circular dichroism spectroscopy shows little unfolding of Cp-CutA1 up to 353 K. This robustness is corroborated by H-?N HSQC spectra at 333 K that is characteristic of a folded protein, suggesting NMR spectroscopy may be a useful tool to further probe the function of the CutA1 proteins. While robust, Cp-CutA1 is not as stable as the homologous protein from a hyperthermophile, perhaps due to a wide ?-bulgein ?2 that protrudes P48 and S49 outside the ?-sheet.

  7. Caffeic acid phenethyl ester inhibits 3-MC-induced CYP1A1 expression through induction of hypoxia-inducible factor-1α

    SciTech Connect (OSTI)

    Kim, Hyung Gyun; Han, Eun Hee; Im, Ji Hye; Lee, Eun Ji; Jin, Sun Woo; Jeong, Hye Gwang

    2015-09-25

    Caffeic acid phenethyl ester (CAPE), a natural component of propolis, is reported to have anticarcinogenic properties, although its precise chemopreventive mechanism remains unclear. In this study, we examined the effects of CAPE on 3-methylcholanthrene (3-MC)-induced CYP1A1 expression and activities. CAPE reduced the formation of the benzo[a]pyrene-DNA adduct. Moreover, CAPE inhibited 3-MC-induced CYP1A1 activity, mRNA expression, protein level, and promoter activity. CAPE treatment also decreased 3-MC-inducible xenobiotic-response element (XRE)-linked luciferase, aryl hydrocarbons receptor (AhR) transactivation and nuclear localization. CAPE induced hypoxia inducible factor-1α (HIF-1α) protein level and HIF-1α responsible element (HRE) transcriptional activity. CAPE-mediated HIF-1α reduced 3-MC-inducible CYP1A1 protein expression. Taken together, CAPE decreases 3-MC-mediated CYP1A1 expression, and this inhibitory response is associated with inhibition of AhR and HIF-1α induction. - Highlights: • CAPE reduced the formation of the benzo[a]pyrene-DNA adduct. • CAPE inhibited 3-MC-induced CYP1A1 expression. • CAPE induced HIF-1α induction. • CAPE-mediated HIF-1α reduced 3-MC-inducible CYP1A1 expression.

  8. The R6A-1 peptide binds to switch II of G{alpha}{sub i1} but is not a GDP-dissociation inhibitor

    SciTech Connect (OSTI)

    Willard, Francis S. . E-mail: fwillard@med.unc.edu; Siderovski, David P.

    2006-01-27

    Heterotrimeric G-proteins are molecular switches that convert signals from membrane receptors into changes in intracellular physiology. Recently, several peptides that bind heterotrimeric G-protein {alpha} subunits have been isolated including the novel G{alpha}{sub i1} . GDP binding peptides R6A and KB-752. The R6A peptide and its minimized derivative R6A-1 interact with G{alpha}{sub i1} . GDP. Based on spectroscopic analysis of BODIPYFL-GTP{gamma}S binding to G{alpha}{sub i1}, it has been reported that R6A-1 has guanine nucleotide dissociation inhibitor (GDI) activity against G{alpha}{sub i1} [W.W. Ja, R.W. Roberts, Biochemistry 43 (28) (2004) 9265-9275]. Using radioligand binding, we show that R6A-1 is not a GDI for G{alpha}{sub i1} subunits. Furthermore, we demonstrate that R6A-1 reduces the fluorescence quantum yield of the G{alpha}{sub i1}-BODIPYFL-GTP{gamma}S complex, thus explaining the previously reported GDI activity as a fluorescence artifact. We further show that R6A-1 has significant sequence similarity to the guanine nucleotide exchange factor peptide KB-752 that binds to switch II of G{alpha}{sub i1}. We use competitive binding analysis to show that R6A-1 also binds to switch II of G{alpha} subunits.

  9. Structure of a CutA1 divalent-cation tolerance protein from Cryptosporidium parvum, the protozoal parasite responsible for cryptosporidiosis

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Buchko, Garry W.; Robinson, Howard; Abendroth, Jan; Clitfon, Mathew C.; Zhang, Yanfeng; Hewitt, Stephen N.; Staker, Bart L.; Van Voorhis, Wesley C.; Mylera, Peter J.

    2015-05-01

    Cryptosporidiosis is an infectious disease caused by protozoan parasites from the Cryptosporidium species. Infection is associated with mild to severe diarrhea that usually resolves spontaneously in healthy human adults, but may lead to severe complications in young children and in immunocompromised patients. The genome of Cryptosporidium parvum contains a gene, CUTA_CRYPI, that may play a role in regulating the intracellular concentration of copper, a toxic element if left unchecked. Here we report the crystal structure for this CutA1 protein, Cp-CutA1, is reported at 2.0 Å resolution (4E98). As observed for other CutA1 structures, the 117-residue protein is a trimer withmore » a core ferrodoxin-like fold. Circular dichroism spectroscopy shows little unfolding of Cp-CutA1 up to 353 K. This robustness is corroborated by ¹H-¹⁵N HSQC spectra at 333 K that is characteristic of a folded protein, suggesting NMR spectroscopy may be a useful tool to further probe the function of the CutA1 proteins. While robust, Cp-CutA1 is not as stable as the homologous protein from a hyperthermophile, perhaps due to a wide β-bulgein β2 that protrudes P48 and S49 outside the β-sheet.« less

  10. Metformin suppresses CYP1A1 and CYP1B1 expression in breast cancer cells by down-regulating aryl hydrocarbon receptor expression

    SciTech Connect (OSTI)

    Do, Minh Truong; Kim, Hyung Gyun; Tran, Thi Thu Phuong; Khanal, Tilak; Choi, Jae Ho; Chung, Young Chul; Jeong, Tae Cheon; Jeong, Hye Gwang

    2014-10-01

    Induction of cytochrome P450 (CYP) 1A1 and CYP1B1 by environmental xenobiotic chemicals or endogenous ligands through the activation of the aryl hydrocarbon receptor (AhR) has been implicated in a variety of cellular processes related to cancer, such as transformation and tumorigenesis. Here, we investigated the effects of the anti-diabetes drug metformin on expression of CYP1A1 and CYP1B1 in breast cancer cells under constitutive and inducible conditions. Our results indicated that metformin down-regulated the expression of CYP1A1 and CYP1B1 in breast cancer cells under constitutive and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced conditions. Down-regulation of AhR expression was required for metformin-mediated decreases in CYP1A1 and CYP1B1 expression, and the metformin-mediated CYP1A1 and CYP1B1 reduction is irrelevant to estrogen receptor α (ERα) signaling. Furthermore, we found that metformin markedly down-regulated Sp1 protein levels in breast cancer cells. The use of genetic and pharmacological tools revealed that metformin-mediated down-regulation of AhR expression was mediated through the reduction of Sp1 protein. Metformin inhibited endogenous AhR ligand-induced CYP1A1 and CYP1B1 expression by suppressing tryptophan-2,3-dioxygenase (TDO) expression in MCF-7 cells. Finally, metformin inhibits TDO expression through a down-regulation of Sp1 and glucocorticoid receptor (GR) protein levels. Our findings demonstrate that metformin reduces CYP1A1 and CYP1B1 expression in breast cancer cells by down-regulating AhR signaling. Metformin would be able to act as a potential chemopreventive agent against CYP1A1 and CYP1B1-mediated carcinogenesis and development of cancer. - Graphical abstract: Schematic of the CYP1A1 and CYP1B1 gene regulation by metformin. - Highlights: • Metformin inhibits CYP1A1 and CYP1B1 expression. • Metformin down-regulates the AhR signaling. • Metformin reduces Sp1 protein expression. • Metformin suppresses TDO expression.

  11. Sulforaphane inhibits CYP1A1 activity and promotes genotoxicity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in vitro

    SciTech Connect (OSTI)

    Yang, Fangxing; Zhuang, Shulin; Zhang, Chao; Dai, Heping; Liu, Weiping

    2013-06-15

    Increasing environmental pollution by carcinogens such as some of persistent organic pollutants (POPs) has prompted growing interest in searching for chemopreventive compounds which are readily obtainable. Sulforaphane (SFN) is isolated from cruciferous vegetables and has the potentials to reduce carcinogenesis through various pathways. In this study, we studied the effects of SFN on CYP1A1 activity and genotoxicity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). The results showed that SFN inhibited TCDD-induced CYP1A1 activity in H4IIE cells by directly inhibiting CYP1A1 activity, probably through binding to aryl hydrocarbon receptor and/or CYP1A1 revealed by molecular docking. However, SFN promoted TCDD-induced DNA damage in yeast cells and reduced the viability of initiated yeast cells. Besides, it is surprising that SFN also failed to reduce genotoxicity induced by other genotoxic reagents which possess different mechanisms to lead to DNA damage. Currently, it is difficult to predict whether SFN has the potentials to reduce the risk of TCDD based on the conflicting observations in the study. Therefore, further studies should be urgent to reveal the function and mechanism of SFN in the stress of such POPs on human health. - Highlights: Sulforaphane inhibited TCDD-induced CYP1A1 activity in H4IIE cells. Sulforaphane may bind to aryl hydrocarbon receptor and/or CYP1A1. Sulforaphane promoted TCDD-induced DNA damage in yeast cells. Sulforaphane may promote DNA damage by DNA strand breaks or DNA alkylation.

  12. Bisphenol A down-regulates rate-limiting Cyp11a1 to acutely inhibit steroidogenesis in cultured mouse antral follicles

    SciTech Connect (OSTI)

    Peretz, Jackye; Flaws, Jodi A.

    2013-09-01

    Bisphenol A (BPA) is the backbone of polycarbonate plastic products and the epoxy resin lining of aluminum cans. Previous studies have shown that exposure to BPA decreases sex steroid hormone production in mouse antral follicles. The current study tests the hypothesis that BPA first decreases the expression levels of the steroidogenic enzyme cytochrome P450 side-chain cleavage (Cyp11a1) and steroidogenic acute regulatory protein (StAR) in mouse antral follicles, leading to a decrease in sex steroid hormone production in vitro. Further, the current study tests the hypothesis that these effects are acute and reversible after removal of BPA. Exposure to BPA (10 μg/mL and 100 μg/mL) significantly decreased expression of Cyp11a1 and StAR beginning at 18 h and 72 h, respectively, compared to controls. Exposure to BPA (10 μg/mL and 100 μg/mL) significantly decreased progesterone levels beginning at 24 h and decreased androstenedione, testosterone, and estradiol levels at 72 h and 96 h compared to controls. Further, after removing BPA from the culture media at 20 h, expression of Cyp11a1 and progesterone levels were restored to control levels by 48 h and 72 h, respectively. Additionally, expression of StAR and levels of androstenedione, testosterone, and estradiol never decreased compared to controls. These data suggest that BPA acutely decreases expression of Cyp11a1 as early as 18 h and this reduction in Cyp11a1 may lead to a decrease in progesterone production by 24 h, followed by a decrease in androstenedione, testosterone, and estradiol production and expression of StAR at 72 h. Therefore, BPA exposure likely targets Cyp11a1 and steroidogenesis, but these effects are reversible with removal of BPA exposure. - Highlights: • BPA may target Cyp11a1 to inhibit steroidogenesis in antral follicles. • BPA may decrease the expression of Cyp11a1 prior to inhibiting steroidogenesis. • The adverse effects of BPA on steroidogenesis in antral follicles are reversible.

  13. Linkage mapping of the gene for Type III collagen (COL3A1) to human chromosome 2q using a VNTR polymorphism

    SciTech Connect (OSTI)

    Tiller, G.E.; Polumbo, P.A.; Summar, M.L. )

    1994-03-15

    The gene for the [alpha]1(III) chain of type III collagen, COL3A1, has been previously mapped to human chromosome 2q24.3-q31 by in situ hybridization. Physical mapping by pulsed-field gel electrophoresis has demonstrated that COL3A1 lies within 35 kb of COL5A2. The authors genotyped the CEPH families at the COL3A2 locus using a pentanucleotide repeat polymorphism within intron 25. They demonstrated significant linkage to 18 anonymous markers as well as the gene for carbamyl phosphate synthetase (CPSI), which had been previously mapped to this region. No recombination was seen between COL3A1 and COL5A2 (Z = 9.93 at [theta] = 0) or D2S24 (Z = 10.55 at [theta] = 0). The locus order is (D2S32-D2S138-D2S148)-(D2S24-COL5A2-COL3A1)-(D2S118-D2S161), with odds of 1:2300 for the next most likely order. These relationships are consistent with the physical mapping of COL3A1 to the distal portion of 2q and place it proximal to CPSI by means of multipoint analysis. These linkage relationships should prove useful in further studies of Ehlers-Danlos syndrome type IV and carbamyl phosphate synthetase I deficiency and provide an additional framework for localizing other genes in this region. 13 refs., 2 figs., 1 tab.

  14. bnw32a1.tmp

    Office of Scientific and Technical Information (OSTI)

    Raw materials are shipped in by truck. or rail. A detailed analysis of the economic estimates for the baseline process is given in Appendix 4. The total capital investment for...

  15. bnw32a1.tmp

    Office of Scientific and Technical Information (OSTI)

    herein do not necessarily state or reflect those of the ... 5.2 Preparation and Testing of Polymer ... evaporator to a damp solid, which was mixed with ...

  16. uth93a1.tmp

    National Nuclear Security Administration (NNSA)

    ... Worman, F. C. V., 1969. Archeological inveigations at the U.S. Atomic Energy Commission's ... Emory's bacchari; Iittleleafmountain mahogany rabbitbrush green rabbitbmsh blackbrush ...

  17. Genetic variation in the CYP1A1 gene is related to circulating PCB118 levels in a population-based sample

    SciTech Connect (OSTI)

    Lind, Lars; Penell, Johanna; Syvänen, Anne-Christine; Axelsson, Tomas; Ingelsson, Erik; Morris, Andrew P.; Lindgren, Cecilia; Salihovic, Samira; Bavel, Bert van; Lind, P. Monica

    2014-08-15

    Several of the polychlorinated biphenyls (PCBs), i.e. the dioxin-like PCBs, are known to induce the P450 enzymes CYP1A1, CYP1A2 and CYP1B1 by activating the aryl hydrocarbon receptor (Ah)-receptor. We evaluated if circulating levels of PCBs in a population sample were related to genetic variation in the genes encoding these CYPs. In the population-based Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study (1016 subjects all aged 70), 21 SNPs in the CYP1A1, CYP1A2 and CYP1B1 genes were genotyped. Sixteen PCB congeners were analysed by high-resolution chromatography coupled to high-resolution mass spectrometry (HRGC/ HRMS). Of the investigated relationships between SNPs in the CYP1A1, CYP1A2 and CYP1B1 and six PCBs (congeners 118, 126, 156, 169, 170 and 206) that captures >80% of the variation of all PCBs measured, only the relationship between CYP1A1 rs2470893 was significantly related to PCB118 levels following strict adjustment for multiple testing (p=0.00011). However, there were several additional SNPs in the CYP1A2 and CYP1B1 that showed nominally significant associations with PCB118 levels (p-values in the 0.003–0.05 range). Further, several SNPs in the CYP1B1 gene were related to both PCB156 and PCB206 with p-values in the 0.005–0.05 range. Very few associations with p<0.05 were seen for PCB126, PCB169 or PCB170. Genetic variation in the CYP1A1 was related to circulating PCB118 levels in the general elderly population. Genetic variation in CYP1A2 and CYP1B1 might also be associated with other PCBs. - Highlights: • We studied the relationship between PCBs and the genetic variation in the CYP genes. • Cross sectional data from a cohort of elderly were analysed. • The PCB levels were evaluated versus 21 SNPs in three CYP genes. • PCB 118 was related to variation in the CYP1A1 gene.

  18. Draft Genome Sequence of thermoalkaliphilic Caldalkalibacillus thermarum strain TA2.A1 Reveals Molecular Adaptations to Extreme pH and Temperature

    SciTech Connect (OSTI)

    Kalamorz, Falk; Keis, Stefanie; Stanton, Jo-Ann; Brown, Steven D; Klingeman, Dawn Marie; Land, Miriam L; Han, Cliff; Martin, S L.; Morgan, Hugh; Cook, Greg

    2011-01-01

    The genes and molecular machines that allow for a thermoalkaliphilic lifestyle have not been defined. To address this goal, we report on the improved high-quality draft genome sequence of Caldalkalibacillus thermarum strain TA2.A1, an obligately aerobic bacterium that grows optimally at pH 9.5 and 65 to 70 C on a wide variety of carbon and energy sources.

  19. Premature chain termination is a unifying mechanism for COL1A1 null alleles in osteogenesis imperfecta type I cell strains

    SciTech Connect (OSTI)

    Willing, M.C.; Deschenes, S.P.; Roberts, E.J.

    1996-10-01

    Nonsense and frameshift mutations, which predict premature termination of translation, often cause a dramatic reduction in the amount of transcript from the mutant allele (nonsense-mediated mRNA decay). In some genes, these mutations also influence RNA splicing and induce skipping of the exon that contains the nonsense codon. To begin to dissect how premature termination alters the metabolism of RNA from the COL1A1 gene, we studied nonsense and frameshift mutations distributed over exons 11-49 of the gene. These mutations were originally identified in 10 unrelated families with osteogenesis imperfecta (OI) type I. We observed marked reduction in steady-state amounts of mRNA from the mutant allele in both total cellular and nuclear RNA extracts of cells from affected individuals, suggesting that nonsense-mediated decay of COL1A1 RNA is a nuclear phenomenon. Position of the mutation within the gene did not influence this observation. None of the mutations induced skipping of either the exon containing the mutation or, for the frameshifts, the downstream exons with the new termination sites. Our data suggest that nonsense and frameshift mutations throughout most of the COL1A1 gene result in a null allele, which is associated with the predictable mild clinical phenotype, OI type I. 42 refs., 6 figs., 1 tab.

  20. A second mutation in the type II procollagen gene (COL2A1) causing Stickler syndrome (arthro-ophthalmopathy) is also a premature termination codon

    SciTech Connect (OSTI)

    Ahmad, N.N.; Knowlton, R.G.; DiMascio, J.; Prockop, D.J. ); McDonald-McGinn, D.M.; Zackai, E.H.; LaRossa, D. )

    1993-01-01

    Genetic linkage analyses suggest that mutations in type II collagen may be responsible for Stickler syndrome, or arthro-ophthalmopathy (AO), in many families. In the present study oligonucleotide primers were developed to amplify and directly sequence eight of the first nine exons of the gene for type II procollagen (COL2A1). Analysis of the eight exons in 10 unrelated probands with AO revealed that one had a single-base mutation in one allele that changed the codon of -CGA- for arginine at amino acid position [alpha]1-9 in exon 7 to a premature termination signal for translation. The second mutation found to cause AO was, therefore, similar to the first in that both created premature termination signals in the COL2A1 gene. Since mutations producing premature termination signals have not previously been detected in genes for fibrillar collagens, the results raise the possibility that such mutations in the COL2A1 gene are a common cause of AO. 33 refs., 4 figs., 2 tabs.

  1. Assessment of Hard-to-Detect Radionuclide Levels in Decommissioning Waste From the Bohunice NPP-A1, Slovakia, for Clearance and Disposal Purposes

    SciTech Connect (OSTI)

    Slavik, O.; Moravek, J.; Stubna, M.

    2002-02-26

    For assessments of hard-to-detect radionuclides (HD-RN) contents in various type of radwastes at the NPP-A1, available empirical data referenced to 137Cs (actinides, 90Sr, 99Tc, 63Ni, 14C) and the theoretical assessment for the remaining HD-RN using calculated RN inventory and a simple model with effective relative (137Cs) spent fuel release fractions was applied. The analytical data of extended radiochemical analysis for the existing available operational radwaste forms have been reviewed for this purpose. 137Cs, 90Sr and 241Am were set up as release markers for partial spent fuel release groups of HD-RNs within which the total fractions of HD-RN released to the operational radwastes were assumed to be constant. It was shown by the assessment carried out that 137Cs and HD-RNs 129I, 99Tc, and partly 79Se and 14C are the main contributors to the disposal dose limit for the radioactive concentrate at NPP A-1. In the case of the radioactive sludge from the operational radwaste system the role of predominant dose contributors belongs to actinides 239,240Pu and 241Am. In the case of clearance of radioactive material from the NPP-A1 site, only the reference radionuclide, 137Cs was predicted to be the most dominant dose contributor. In all of these cases the estimated contributions of other hard-to-detect radionuclides to respective disposal or release dose limit are lower by 2 and more orders of magnitude. As a lesson learned, the most attention is proposed to focus on the control and measurement of the critical HD-RNs indicated by the assessment. For the control of less important HD-RNs, the developed release coefficient method is sufficient to be applied.

  2. Hypoxia perturbs aryl hydrocarbon receptor signaling and CYP1A1 expression induced by PCB 126 in human skin and liver-derived cell lines

    SciTech Connect (OSTI)

    Vorrink, Sabine U.; Severson, Paul L.; Kulak, Mikhail V.; Futscher, Bernard W.; Domann, Frederick E.

    2014-02-01

    The aryl hydrocarbon receptor (AhR) is an important mediator of toxic responses after exposure to xenobiotics including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and dioxin-like polychlorinated biphenyls (PCBs). Activation of AhR responsive genes requires AhR dimerization with the aryl hydrocarbon receptor nuclear translocator (ARNT), a heterodimeric partner also shared by the hypoxia-inducible factor-1α (HIF-1α) protein. TCDD-stimulated AhR transcriptional activity can be influenced by hypoxia; however, it less well known whether hypoxia interferes with AhR transcriptional transactivation in the context of PCB-mediated AhR activation in human cells. Elucidation of this interaction is important in liver hepatocytes which extensively metabolize ingested PCBs and experience varying degrees of oxygen tension during normal physiologic function. This study was designed to assess the effect of hypoxia on AhR transcriptional responses after exposure to 3,3′,4,4′,5-pentachlorobiphenyl (PCB 126). Exposure to 1% O{sub 2} prior to PCB 126 treatment significantly inhibited CYP1A1 mRNA and protein expression in human HepG2 and HaCaT cells. CYP1A1 transcriptional activation was significantly decreased upon PCB 126 stimulation under conditions of hypoxia. Additionally, hypoxia pre-treatment reduced PCB 126 induced AhR binding to CYP1 target gene promoters. Importantly, ARNT overexpression rescued cells from the inhibitory effect of hypoxia on XRE-luciferase reporter activity. Therefore, the mechanism of interference of the signaling crosstalk between the AhR and hypoxia pathways appears to be at least in part dependent on ARNT availability. Our results show that AhR activation and CYP1A1 expression induced by PCB 126 were significantly inhibited by hypoxia and hypoxia might therefore play an important role in PCB metabolism and toxicity. - Highlights: • Significant crosstalk exists between AhR and HIF-1α signaling. • Hypoxia perturbs PCB 126 induced AhR function and

  3. Test and demonstration of a 1-MW wellhead generator: helical screw expander power plant, Model 76-1. Final report to the International Energy Agency

    SciTech Connect (OSTI)

    Not Available

    1985-07-04

    A 1-MW geothermal wellhead power plant incorporating a Lysholm or helical screw expander (HSE) was field tested between 1980 and 1983 by Mexico, Italy, and New Zealand with technical assistance from the United States. The objectives were to provide data on the reliability and performance of the HSE and to assess the costs and benefits of its use. The range of conditions under which the HSE was tested included loads up to 933 kW, mass flowrates of 14,600 to 395, 000 lbs/hr, inlet pressures of 64 to 220 psia, inlet qualities of 0 to 100%, exhaust pressures of 3.1 to 40 psia, total dissolved solids up to 310,000 ppM, and noncondensible gases up to 38% of the vapor mass flow. Typical machine efficiencies of 40 to 50% were calculated. For most operations efficiency increased approximately logarithmically with shaft power, while inlet quality and rotor speed had only small effects. The HSE was designed with oversized internal clearances in the expectation that adherent scale would form during operation. Improvements in machine efficiency of 3.5 to 4 percentage points were observed over some test periods with some scale deposition. A comparison with a 1-MW back-pressure turbine showed that the HSE can compete favorably under certain conditions. The HSE was found to be a rugged energy conversion machine for geothermal applications, but some subsystems were found to require further development. 7 refs., 28 figs., 5 tabs.

  4. Location of the spinal cerebellar ataxia 2 locus to a 1 cM interval on chromsome 12q23-24.1

    SciTech Connect (OSTI)

    Allotey, R.; Twells, R.; Orozco, G.

    1994-09-01

    Spinocerebellar ataxia 2 (SCA2) is a dominantly inherited neurodegenerative disorder characterised by progressive ataxia, dysarthria, dysmetria and dysdiadochokinesia. We have previously assigned the disease locus to chromosome 12q23-24.1 in a population from the Holguin province, Cuba, within a 31 cM interval flanked by the anonymous marker D12S53 and the phospholipase A2 gene (PLA2). Clinical as much as genealogical and geographical evidence indicate that the Cuban pedigrees are homogeneous and descend from a common ancestor. We now report fine genetic mapping of the disease locus with fourteen microsatellite loci known to span this region, which positions SCA2 in a 1 cM interval defined by the loci D12S84-AFM291xe9. Observation of a common haplotype segregating with the disease supports the existence of a founder effect in the Holguin pedigrees.

  5. Synthesis, selected coordination chemistry and extraction behavior of a (phosphinoylmethyl)pyridyl N-oxide-functionalized ligand based upon a 1,4-diazepane platform

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Ouizem, Sabrina; Rosario Amorin, Daniel; Dickie, Diane A.; Cramer, Roger E.; Campana, Charles F.; Hay, Benjamin P.; Podair, Julien; Delmau, Laetitia H.; Paine, Robert T.

    2015-05-09

    For syntheses of new multidentate chelating ligands ((6,6'4(1,4-diazepane-1,4-diyl)bis(methylene))bis(pyridine-6,2-diyl))bis(methylene))bis(diphenylphosphine oxide) (2) and 6,6'-((1,4-diazepane1,4-diyl)bis(methylene))bis(2-((diphenylphosphoryl)methyl)pyridine 1-oxide) (3), based upon a 1,4-diazepane platform functionalized with 2-(diphenylphosphinoylmethyl)pyridine P-oxide and 2-(diphenylphosphinoylmethyl)pyridine NP-dioxide fragments, respectively, the results are reported. Our results from studies of the coordination chemistry of the ligands with selected lanthanide nitrates and Cu(BF4)(2) are outlined, and crystal structures for two complexes, [Cu(2)](BF4)2 and [Cu(3)](BF4)2, are described along with survey Eu(III) and Am(III) solvent extraction analysis, for 3.

  6. Synthesis, selected coordination chemistry and extraction behavior of a (phosphinoylmethyl)pyridyl N-oxide-functionalized ligand based upon a 1,4-diazepane platform

    SciTech Connect (OSTI)

    Ouizem, Sabrina; Rosario Amorin, Daniel; Dickie, Diane A.; Cramer, Roger E.; Campana, Charles F.; Hay, Benjamin P.; Podair, Julien; Delmau, Laetitia H.; Paine, Robert T.

    2015-05-09

    For syntheses of new multidentate chelating ligands ((6,6'4(1,4-diazepane-1,4-diyl)bis(methylene))bis(pyridine-6,2-diyl))bis(methylene))bis(diphenylphosphine oxide) (2) and 6,6'-((1,4-diazepane1,4-diyl)bis(methylene))bis(2-((diphenylphosphoryl)methyl)pyridine 1-oxide) (3), based upon a 1,4-diazepane platform functionalized with 2-(diphenylphosphinoylmethyl)pyridine P-oxide and 2-(diphenylphosphinoylmethyl)pyridine NP-dioxide fragments, respectively, the results are reported. Our results from studies of the coordination chemistry of the ligands with selected lanthanide nitrates and Cu(BF4)(2) are outlined, and crystal structures for two complexes, [Cu(2)](BF4)2 and [Cu(3)](BF4)2, are described along with survey Eu(III) and Am(III) solvent extraction analysis, for 3.

  7. Inhibitory effect of CT domain of CCN3/NOV on proliferation and differentiation of osteogenic mesenchymal stem cells, Kusa-A1

    SciTech Connect (OSTI)

    Katsuki, Yuko; Sakamoto, Kei; Minamizato, Tokutaro; Makino, Hatsune; Umezawa, Akihiro; Ikeda, Masa-aki; Perbal, Bernard; Amagasa, Teruo; Yamaguchi, Akira; Katsube, Ken-ichi

    2008-04-11

    CCN3/NOV activates the Notch signal through the carboxyl terminal cysteine-rich (CT) domain. CCN3 transfection to Kusa-A1 inhibited osteogenic differentiation and cell proliferation, which is accompanied by upregulation of Hes/Hey, Notch downstream targets, and p21, a CDK inhibitor. Upregulation of Hes/Hey and p21 was abrogated by the deletion of CT domain. Anti-proliferative activity of CCN3 was also abrogated by CT domain deletion whereas anti-osteogenic activity was not completely abrogated. We found that CT domain-deleted CCN3 still possesses antagonistic effect on BMP-2. These results suggest that CCN3 employs Notch and BMP pathways in anti-osteogenic activity while it inhibits cell proliferation uniquely by Notch/p21 pathway.

  8. Categorical Exclusion (CX) Determinations By CX | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    CX Categorical Exclusion (CX) Determinations By CX A. - Categorical Exclusions Applicable to General Agency Actions A1 - Routine DOE business actions A2 - Clarifying or administrative contract actions A3 - Certain actions by Office of Hearings and Appeals A4 - Interpretations and rulings for existing regulations A5 - Interpretive rulemakings with no change in environmental effect A6 - Procedural rulemakings A7 - [Reserved] A8 - Awards of certain contracts A9 - Information gathering, analysis,

  9. Biophysical Analysis of Anopheles gambiae Leucine-Rich Repeat Proteins APL1A1, APL1B and APL1C and Their Interaction with LRIM1

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Williams, Marni; Summers, Brady J.; Baxter, Richard H. G.; Kobe, Bostjan

    2015-03-16

    Natural infection of Anopheles gambiae by malaria-causing Plasmodium parasites is significantly influenced by the APL1 genetic locus. The locus contains three closely related leucine-rich repeat (LRR) genes, APL1A, APL1B and APL1C. Multiple studies have reported the participation of APL1A—C in the immune response of A. gambiae to invasion by both rodent and human Plasmodium isolates. APL1C forms a heterodimer with the related LRR protein LRIM1 via a C-terminal coiled-coil domain that is also present in APL1A and APL1B. The LRIM1/APL1C heterodimer protects A. gambiae from infection by binding the complement-like protein TEP1 to form a stable and active immune complex.more » We report solution x-ray scatting data for the LRIM1/APL1C heterodimer, the oligomeric state of LRIM1/APL1 LRR domains in solution and the crystal structure of the APL1B LRR domain. The LRIM1/APL1C heterodimeric complex has a flexible and extended structure in solution. In contrast to the APL1A, APL1C and LRIM1 LRR domains, the APL1B LRR domain is a homodimer. The crystal structure of APL1B-LRR shows that the homodimer is formed by an N-terminal helix that complements for the absence of an N-terminal capping motif in APL1B, which is a unique distinction within the LRIM1/APL1 protein family. Full-length APL1A1 and APL1B form a stable complex with LRIM1. Our results support a model in which APL1A1, APL1B and APL1C can all form an extended, flexible heterodimer with LRIM1, providing a repertoire of functional innate immune complexes to protect A. gambiae from a diverse array of pathogens.« less

  10. TH-A-9A-04: Incorporating Liver Functionality in Radiation Therapy Treatment Planning

    SciTech Connect (OSTI)

    Wu, V; Epelman, M; Feng, M; Cao, Y; Wang, H; Romeijn, E; Matuszak, M

    2014-06-15

    Purpose: Liver SBRT patients have both variable pretreatment liver function (e.g., due to degree of cirrhosis and/or prior treatments) and sensitivity to radiation, leading to high variability in potential liver toxicity with similar doses. This work aims to explicitly incorporate liver perfusion into treatment planning to redistribute dose to preserve well-functioning areas without compromising target coverage. Methods: Voxel-based liver perfusion, a measure of functionality, was computed from dynamic contrast-enhanced MRI. Two optimization models with different cost functions subject to the same dose constraints (e.g., minimum target EUD and maximum critical structure EUDs) were compared. The cost functions minimized were EUD (standard model) and functionality-weighted EUD (functional model) to the liver. The resulting treatment plans delivering the same target EUD were compared with respect to their DVHs, their dose wash difference, the average dose delivered to voxels of a particular perfusion level, and change in number of high-/low-functioning voxels receiving a particular dose. Two-dimensional synthetic and three-dimensional clinical examples were studied. Results: The DVHs of all structures of plans from each model were comparable. In contrast, in plans obtained with the functional model, the average dose delivered to high-/low-functioning voxels was lower/higher than in plans obtained with its standard counterpart. The number of high-/low-functioning voxels receiving high/low dose was lower in the plans that considered perfusion in the cost function than in the plans that did not. Redistribution of dose can be observed in the dose wash differences. Conclusion: Liver perfusion can be used during treatment planning potentially to minimize the risk of toxicity during liver SBRT, resulting in better global liver function. The functional model redistributes dose in the standard model from higher to lower functioning voxels, while achieving the same target EUD and satisfying dose limits to critical structures. This project is funded by MCubed and grant R01-CA132834.

  11. TH-A-9A-06: Inverse Planning of Gamma Knife Radiosurgery Using...

    Office of Scientific and Technical Information (OSTI)

    obtained by solving a constrained integer-linear problem. (4) The shots are placed into ... Subject: 60 APPLIED LIFE SCIENCES; ALGORITHMS; GEOMETRY; KERNELS; NEOPLASMS; OPTIMIZATION; ...

  12. Annexin A9 (ANXA9) biomarker and therapeutic target in epithelial cancer

    DOE Patents [OSTI]

    Hu, Zhi; Kuo, Wen-Lin; Neve, Richard M.; Gray, Joe W.

    2012-06-12

    Amplification of the ANXA9 gene in human chromosomal region 1q21 in epithelial cancers indicates a likelihood of both in vivo drug resistance and metastasis, and serves as a biomarker indicating these aspects of the disease. ANXA9 can also serve as a therapeutic target. Interfering RNAs (iRNAs) (such as siRNA and miRNA) and shRNA adapted to inhibit ANXA9 expression, when formulated in a therapeutic composition, and delivered to cells of the tumor, function to treat the epithelial cancer.

  13. Light hadron spectra in the constituent quark model with the Kobayashi-Kondo-Maskawa-'t Hooft effective U {sub A} (1) symmetry breaking interaction

    SciTech Connect (OSTI)

    Dmitrasinovic, V. . E-mail: dmitrasin@yahoo.com; Toki, H.

    2006-02-15

    We make a critical comparison of several versions of instanton-induced interactions present in the literature, all based on ITEP group's extension to three colours and flavours of 't Hooft's effective lagrangian, with the predictions of the phenomenological Kobayashi-Kondo-Maskawa (KKM) chiral quark lagrangian. We analyze the effects of all versions of the effective U {sub A} (1) symmetry breaking interactions on light hadron spectra in the non-relativistic constituent quark model. We show that the KKMT force, when used as a residual hyperfine interaction reproduces the correct ordering of pseudoscalar and vector mesons even without explicitly taking chiral symmetry into account. Moreover, the nucleon spectra are also correctly reproduced, only the Roper resonance remains too high, albeit lower than usual, at 1660 MeV. The latter's lower than expected mass is not due to a small excitation energy, as in the Glozman-Riska (GR) model, but to a combination of colour, flavour, and spatial wave function properties that enhance the relevant matrix elements. The KKMT interaction explicitly depends on flavour and spin of the quarks, but unlike the GR flavour-spin one it has a firm footing in QCD. In the process we provide several technical advances, in particular we show the first explicit derivation of the three-body Fierz transformation and apply it to the KKM interaction. We also discuss the ambiguities associated with the colour degree of freedom.

  14. An N-terminal glycine to cysteine mutation in the collagen COL1A1 gene produces moderately severe osteogenesis imperfecta

    SciTech Connect (OSTI)

    Wilcox, W.; Scott, L.; Cohn, D.

    1994-09-01

    Osteogenesis imperfecta (OI) is usually due to mutations in the type I procollagen genes COL1A1 and COL1A2. Point mutations close to the N-terminus are generally milder than those near the C-terminus of the molecule (the gradient hypothesis of collagen mutations). We describe a patient with moderately severe OI due to a mutation in the N-terminal portion of the triple helical domain of the {alpha}1(I) chain. Electrophoretic analysis of collagen isolated from fibroblast cultures suggested the abnormal presence of a cysteine in the N-terminal portion of the {alpha}1(I) chain. Five overlapping DNA fragments amplified from fibroblast RNA were screened for mutations using single strand conformational polymorphism (SSCP) and heteroduplex analyses. Direct DNA sequence analysis of the single positive fragment demonstrated a G to T transversion, corresponding to a glycine to cysteine substitution at position 226 of the triple helical domain of the {alpha}1(I) chain. The mutation was confirmed by restriction enzyme analysis of amplified genomic DNA. The mutation was not present in fibroblasts from either phenotypically normal parent. Combining this mutation with other reported mutations, glycine to cysteine substitutions at positions 205, 211, 223, and 226 produce a moderately severe phenotype whereas flanking mutations at positions 175 and 382 produce a mild phenotype. This data supports a regional rather than a gradient model of the relationship between the nature and location of type I collagen mutations and OI phenotype.

  15. To1 Col. A. 8. Pry., Jr. Prom L. c. Furney

    Office of Legacy Management (LM)

    . ' .... 200 lb6 B+ 2.0 lbe UjoB the A. C. Spark Plxq Company'aartified on IebmAr'y 4, 1947 that .they have reoelrad II-05 the UaabatknEaginoer Di&riCt 909.5 lb6 Of FWO, 33 lbs ...

  16. THE DEVELOPMENT OF A 1990 GLOBAL INVENTORY FOR SO(X) AND NO(X) ON A 1(DEGREE) X 1(DEGREE) LATITUDE-LONGITUDE GRID.

    SciTech Connect (OSTI)

    VAN HEYST,B.J.

    1999-10-01

    Sulfur and nitrogen oxides emitted to the atmosphere have been linked to the acidification of water bodies and soils and perturbations in the earth's radiation balance. In order to model the global transport and transformation of SO{sub x} and NO{sub x}, detailed spatial and temporal emission inventories are required. Benkovitz et al. (1996) published the development of an inventory of 1985 global emissions of SO{sub x} and NO{sub x} from anthropogenic sources. The inventory was gridded to a 1{degree} x 1{degree} latitude-longitude grid and has served as input to several global modeling studies. There is now a need to provide modelers with an update of this inventory to a more recent year, with a split of the emissions into elevated and low level sources. This paper describes the development of a 1990 update of the SO{sub x} and NO{sub x} global inventories that also includes a breakdown of sources into 17 sector groups. The inventory development starts with a gridded global default EDGAR inventory (Olivier et al, 1996). In countries where more detailed national inventories are available, these are used to replace the emissions for those countries in the global default. The gridded emissions are distributed into two height levels (0-100m and >100m) based on the final plume heights that are estimated to be typical for the various sectors considered. The sources of data as well as some of the methodologies employed to compile and develop the 1990 global inventory for SO{sub x} and NO{sub x} are discussed. The results reported should be considered to be interim since the work is still in progress and additional data sets are expected to become available.

  17. A:\\1FRONT(REVISED).PDF

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... and traffic management, patents law, real and personal property management, ... Report (1995), and DOE's Contract Reform Team Report (1994) all have one thing in common. ...

  18. Microsoft Word - table_A1.doc

    U.S. Energy Information Administration (EIA) Indexed Site

    These differences may be due to quantities lost or to the effects of differences in company accounting systems in terms of scope and definition. A positive "unaccounted for" volume ...

  19. Diagnostics from a 1-D atmospheric column

    SciTech Connect (OSTI)

    Flatley, J.M.; Mace, G.

    1996-04-01

    Various diagnostics were computed from an array of radiosondes during an intensive field operation arranged by the Atmospheric Radiation Measurement Program. The network data was centered around the site at Lamont, Oklahoma. The apparent heat source and apparent moisture sink were computed and compared to the kinematic vertical velocity for both real data and the mesoscale analysis and prediction system. Three different case studies of various weathe regimes were examined.

  20. A1.5 Fusion Performance

    SciTech Connect (OSTI)

    Amendt, P

    2011-03-31

    Analysis and radiation hydrodynamics simulations for expected high-gain fusion target performance on a demonstration 1-GWe Laser Inertial Fusion Energy (LIFE) power plant in the mid-2030s timeframe are presented. The required laser energy driver is 2.2 MJ at a 0.351-{micro}m wavelength, and a fusion target gain greater than 60 at a repetition rate of 16 Hz is the design goal for economic and commercial attractiveness. A scaling-law analysis is developed to benchmark the design parameter space for hohlraum-driven central hot-spot ignition. A suite of integrated hohlraum simulations is presented to test the modeling assumptions and provide a basis for a near-term experimental resolution of the key physics uncertainties on the National Ignition Facility (NIF). The NIF is poised to demonstrate ignition by 2012 based on the central hot spot (CHS) mode of ignition and propagating thermonuclear burn [1]. This immediate prospect underscores the imperative and timeliness of advancing inertial fusion as a carbon-free, virtually limitless source of energy by the mid-21st century to substantially offset fossil fuel technologies. To this end, an intensive effort is underway to leverage success at the NIF and to provide the foundations for a prototype 'LIFE.1' engineering test facility by {approx}2025, followed by a commercially viable 'LIFE.2' demonstration power plant operating at 1 GWe by {approx}2035. The current design goal for LIFE.2 is to accommodate {approx}2.2 MJ of laser energy (entering the high-Z radiation enclosure or 'hohlraum') at a 0.351-{micro}m wavelength operating at a repetition rate of 16 Hz and to provide a fusion target yield of 132 MJ. To achieve this design goal first requires a '0-d' analytic gain model that allows convenient exploration of parameter space and target optimization. This step is then followed by 2- and 3-dimensional radiation-hydrodynamics simulations that incorporate laser beam transport, x-ray radiation transport, atomic physics, and thermonuclear burn [2]. These simulations form the basis for assessing the susceptibility to hydrodynamic instability growth, target performance margins, laser backscatter induced by plasma density fluctuations within the hohlraum, and the threat spectrum emerging from the igniting capsule, e.g., spectra, fluences and anisotropy of the x rays and ions, for input into the chamber survivability calculations. The simulations follow the guidelines of a 'point design' methodology, which formally designates a well-defined milestone in concept development that meets established criteria for experimental testing. In Section 2, the 0-d analytic gain model to survey gain versus laser energy parameter space is discussed. Section 3 looks at the status of integrated hohlraum simulations and the needed improvements in laser-hohlraum coupling efficiency to meet the LIFE.2 threshold (net) target gain of {approx}60. Section 4 considers advanced hohlraum designs to well exceed the LIFE.2 design goal for satisfactory performance margins. We summarize in Sec. 5.

  1. Residential Refrigerators-Freezers (Appendix A1)

    Broader source: Energy.gov [DOE]

    The Department of Energy (DOE) develops standardized data templates for reporting the results of tests conducted in accordance with current DOE test procedures. Templates may be used by third-party laboratories under contract with DOE that conduct testing in support of ENERGY STAR® verification, DOE rulemakings, and enforcement of the federal energy conservation standards.

  2. G to A substitution in 5{prime} donor splice site of introns 18 and 48 of COL1A1 gene of type I collagen results in different splicing alternatives in osteogenesis imperfecta type I cell strains

    SciTech Connect (OSTI)

    Willing, M.; Deschenes, S.

    1994-09-01

    We have identified a G to A substitution in the 5{prime} donor splice site of intron 18 of one COL1A1 allele in two unrelated families with osteogenesis imperfecta (OI) type I. A third OI type I family has a G to A substitution at the identical position in intron 48 of one COL1A1 allele. Both mutations abolish normal splicing and lead to reduced steady-state levels of mRNA from the mutant COL1A1 allele. The intron 18 mutation leads to both exon 18 skipping in the mRNA and to utilization of a single alternative splice site near the 3{prime} end of exon 18. The latter results in deletion of the last 8 nucleotides of exon 18 from the mRNA, a shift in the translational reading-frame, and the creation of a premature termination codon in exon 19. Of the potential alternative 5{prime} splice sites in exon 18 and intron 18, the one utilized has a surrounding nucleotide sequence which most closely resembles that of the natural splice site. Although a G to A mutation was detected at the identical position in intron 48 of one COL1A1 allele in another OI type I family, nine complex alternative splicing patterns were identified by sequence analysis of cDNA clones derived from fibroblast mRNA from this cell strain. All result in partial or complete skipping of exon 48, with in-frame deletions of portions of exons 47 and/or 49. The different patterns of RNA splicing were not explained by their sequence homology with naturally occuring 5{prime} splice sites, but rather by recombination between highly homologous exon sequences, suggesting that we may not have identified the major splicing alternative(s) in this cell strain. Both G to A mutations result in decreased production of type I collagen, the common biochemical correlate of OI type I.

  3. Minimally Invasive Magnetic Resonance Imaging-Guided Free-Hand Aspiration of Symptomatic Nerve Route Compressing Lumbosacral Cysts Using a 1.0-Tesla Open Magnetic Resonance Imaging System

    SciTech Connect (OSTI)

    Bucourt, Maximilian de Streitparth, Florian Collettini, Federico; Guettler, Felix; Rathke, Hendrik; Lorenz, Britta; Rump, Jens; Hamm, Bernd; Teichgraeber, U. K.

    2012-02-15

    Purpose: To evaluate the feasibility of minimally invasive magnetic resonance imaging (MRI)-guided free-hand aspiration of symptomatic nerve route compressing lumbosacral cysts in a 1.0-Tesla (T) open MRI system using a tailored interactive sequence. Materials and Methods: Eleven patients with MRI-evident symptomatic cysts in the lumbosacral region and possible nerve route compressing character were referred to a 1.0-T open MRI system. For MRI interventional cyst aspiration, an interactive sequence was used, allowing for near real-time position validation of the needle in any desired three-dimensional plane. Results: Seven of 11 cysts in the lumbosacral region were successfully aspirated (average 10.1 mm [SD {+-} 1.9]). After successful cyst aspiration, each patient reported speedy relief of initial symptoms. Average cyst size was 9.6 mm ({+-}2.6 mm). Four cysts (8.8 {+-} 3.8 mm) could not be aspirated. Conclusion: Open MRI systems with tailored interactive sequences have great potential for cyst aspiration in the lumbosacral region. The authors perceive major advantages of the MR-guided cyst aspiration in its minimally invasive character compared to direct and open surgical options along with consecutive less trauma, less stress, and also less side-effects for the patient.

  4. http://ecfr.gpoaccess.gov/cgi/t/text/text-idx?c=ecfr&sid=d259a9

    National Nuclear Security Administration (NNSA)

    10: Energy Browse Previous | Browse Next PART 835-OCCUPATIONAL RADIATION PROTECTION ... under section 1701 of the Atomic Energy Act; (2) Activities conducted under the ...

  5. Edge-terminated molybdenum disulfide with a 9.4-Å interlayer spacing for electrochemical hydrogen production

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Gao, Min -Rui; Chan, Maria K. Y.; Sun, Yugang

    2015-07-03

    In this study, layered molybdenum disulfide has demonstrated great promise as a low-cost alternative to platinum-based catalysts for electrochemical hydrogen production from water. Research effort on this material has focused mainly on synthesizing highly nanostructured molybdenum disulfide that allows the exposure of a large fraction of active edge sites. Here we report a promising microwave-assisted strategy for the synthesis of narrow molybdenum disulfide nanosheets with edge-terminated structure and a significantly expanded interlayer spacing, which exhibit striking kinetic metrics with onset potential of -103 mV, Tafel slope of 49 mV per decade and exchange current density of 9.62 × 10-3 mAmore » cm-2, performing among the best of current molybdenum disulfide catalysts. Besides benefits from the edge-terminated structure, the expanded interlayer distance with modified electronic structure is also responsible for the observed catalytic improvement, which suggests a potential way to design newly advanced molybdenum disulfide catalysts through modulating the interlayer distance.« less

  6. Edge-terminated molybdenum disulfide with a 9.4-Å interlayer spacing for electrochemical hydrogen production

    SciTech Connect (OSTI)

    Gao, Min -Rui; Chan, Maria K. Y.; Sun, Yugang

    2015-07-03

    In this study, layered molybdenum disulfide has demonstrated great promise as a low-cost alternative to platinum-based catalysts for electrochemical hydrogen production from water. Research effort on this material has focused mainly on synthesizing highly nanostructured molybdenum disulfide that allows the exposure of a large fraction of active edge sites. Here we report a promising microwave-assisted strategy for the synthesis of narrow molybdenum disulfide nanosheets with edge-terminated structure and a significantly expanded interlayer spacing, which exhibit striking kinetic metrics with onset potential of -103 mV, Tafel slope of 49 mV per decade and exchange current density of 9.62 × 10-3 mA cm-2, performing among the best of current molybdenum disulfide catalysts. Besides benefits from the edge-terminated structure, the expanded interlayer distance with modified electronic structure is also responsible for the observed catalytic improvement, which suggests a potential way to design newly advanced molybdenum disulfide catalysts through modulating the interlayer distance.

  7. TH-A-9A-01: Active Optical Flow Model: Predicting Voxel-Level Dose Prediction in Spine SBRT

    SciTech Connect (OSTI)

    Liu, J; Wu, Q.J.; Yin, F; Kirkpatrick, J; Cabrera, A; Ge, Y

    2014-06-15

    Purpose: To predict voxel-level dose distribution and enable effective evaluation of cord dose sparing in spine SBRT. Methods: We present an active optical flow model (AOFM) to statistically describe cord dose variations and train a predictive model to represent correlations between AOFM and PTV contours. Thirty clinically accepted spine SBRT plans are evenly divided into training and testing datasets. The development of predictive model consists of 1) collecting a sequence of dose maps including PTV and OAR (spinal cord) as well as a set of associated PTV contours adjacent to OAR from the training dataset, 2) classifying data into five groups based on PTV's locations relative to OAR, two “Top”s, “Left”, “Right”, and “Bottom”, 3) randomly selecting a dose map as the reference in each group and applying rigid registration and optical flow deformation to match all other maps to the reference, 4) building AOFM by importing optical flow vectors and dose values into the principal component analysis (PCA), 5) applying another PCA to features of PTV and OAR contours to generate an active shape model (ASM), and 6) computing a linear regression model of correlations between AOFM and ASM.When predicting dose distribution of a new case in the testing dataset, the PTV is first assigned to a group based on its contour characteristics. Contour features are then transformed into ASM's principal coordinates of the selected group. Finally, voxel-level dose distribution is determined by mapping from the ASM space to the AOFM space using the predictive model. Results: The DVHs predicted by the AOFM-based model and those in clinical plans are comparable in training and testing datasets. At 2% volume the dose difference between predicted and clinical plans is 4.2±4.4% and 3.3±3.5% in the training and testing datasets, respectively. Conclusion: The AOFM is effective in predicting voxel-level dose distribution for spine SBRT. Partially supported by NIH/NCI under grant #R21CA161389 and a master research grant by Varian Medical System.

  8. TU-A-9A-07: X-Ray Acoustic Computed Tomography (XACT): 100% Sensitivity to X-Ray Absorption

    SciTech Connect (OSTI)

    Xiang, L; Ahmad, M; Nikoozadeh, A; Pratx, G; Khuri-Yakub, B; Xing, L

    2014-06-15

    Purpose: To assess whether X-ray acoustic computed tomography (XACT) is more sensitive to X-ray absorption than that of the conventional X-ray imaging. Methods: First, a theoretical model was built to analyze the X-ray absorption sensitivity of XACT imaging and conventional X-ray imaging. Second, an XACT imaging system was developed to evaluate the X-ray induced acoustic signal generation as well as the sensitivity improvement over transmission x-ray imaging. Ultra-short x-ray pulses (60-nanosecond) were generated from an X-ray source operated at the energy of 150 kVp with a 10-Hz repetition rate. The X-ray pulse was synchronized with the acoustic detection via a x-ray scintillation triggering to acquire the X-ray induced acoustic signal. Results: Theoretical analysis shows that X-ray induced acoustic signal is sensitive only to the X-ray absorption, while completely insensitive to out the X-ray scattering and fluorescence. XACT has reduced background and increased contrast-to-noise ratio, and therefore has increased sensitivity compared to transmission x-ray imaging. For a 50-μm size, gadolinium insertion in tissue exposed to 40 keV X-rays; the sensitivity of XACT imaging is about 28.9 times higher than that of conventional X-ray imaging. Conclusion: X-ray acoustic computer tomography (XACT) as a new imaging modality combines X-ray absorption contrast and high ultrasonic resolution in a single modality. It is feasible to improve the imaging sensitivity with XACT imaging compared with conventional X-ray imaging. Taking advantage of the high ultrasonic resolution, it is possible to perform 3-D imaging with a single x-ray pulse with arrays of transducers without any mechanical motion of the imaging system. This single-shot capability offers the potential of reducing radiation dose by a factor of 1000, and imaging 100 times faster when compared to the conventional X-ray CT, and thus revolutionizing x-ray imaging applications in medicine and biology. The authors gratefully acknowledge the Department of Defense Prostate Cancer Research Programs W81XWH-13-1-0481 (LX), the National Institutes of Health 1R01 CA133474 and 1R21 A153587, and SRFDP (20124407120012) for funding.

  9. NOI1VU1SININQV NOLLVINUOdNI A9H3N3 AO^HNH

    Gasoline and Diesel Fuel Update (EIA)

    Administration NEMS Freight Transportation Module Improvement Study Release date: February 3, 2015 The U.S. Energy Information Administration (EIA) contracted with IHS Global, Inc. (IHS) to analyze the relationship between the value of industrial output, physical output, and freight movement in the United States for use in updating analytic assumptions and modeling structure within the National Energy Modeling System (NEMS) freight transportation module, including forecasting methodologies

  10. http://www.phmsa.dot.gov/portal/site/PHMSA/menuitem.ebdc7a8a7e3

    National Nuclear Security Administration (NNSA)

    Library Careers | Contact Us | No Fear | Privacy Policy | FOIA | Accessibility | FAQs | Web Policies | Site Map | Download Acrobat Page 2 of 2 PHMSA - Library - Ten Year Hazardous ...

  11. WE-G-17A-07: Investigation of the Influence of the Electron Return Effect (ERE) On the Dose Distribution in Rectal Cancer Patients On a 1.5T MR-Linac

    SciTech Connect (OSTI)

    Uilkema, S; Heide, U; Nijkamp, J; Sonke, J; Moreau, M

    2014-06-15

    Purpose: The purpose of this planning study is to investigate the influence of the ERE on the day-to-day dose distribution in rectal cancer patients, where changes in gas-pockets frequently occur. Methods: Daily CT scans of 5 patients treated neo-adjuvant with 5x5Gy for rectal cancer were used. We optimized two plans on the planning CT (Monaco, 1 mm3 dosegrid), a conventional 7-field 6MV IMRT plan (Dconv) and a plan in the presence of a 1.5T field (Dmrl). We recalculated the plans on all repeat-CT scans and evaluated under/over-dosage of the daily CTVs. Changes of more than 1% were considered significant. In the bowel area, we investigated the relative dose changes due to the ERE, where the contribution of the ERE was separated from other effects such as attenuation. Results: Both plans were comparable and compliant with ICRU 62 for all patients. For 2 fractions in one patient under-dosage in the CTV was significant, due to a disappearing gas-pocket. Here the V95 was 96.82 and 97.36% in in Dmrl compared to 98.85 and 98.66% in Dconv, respectively. For 3 fractions in another patient appearing gas-pockets resulted in significant over-dosage of the CTV. In these fractions the V107 was 1.882.68% in Dmrl compared to 0.331.27% in Dconv. In the bowel area the dose changes attributable to the ERE were approximately 5% in 1cc, at low dose levels. Conclusion: We were able to calculate acceptable treatment plans with and without a magnetic field. The ERE was present in the Dmrl, but the volumetric effect within the CTV was limited. Outside the CTV relative dose differences were similar, but on small volumes at lower, less relevant dose levels. This suggests that there is no clinical relevant ERE on dose distributions in rectal cancer patients on a 1.5T MR-Linac.

  12. The tribology of PS212 coatings and PM212 composites for the lubrication of titanium 6A1-4V components of a Stirling engine space power system

    SciTech Connect (OSTI)

    Sliney, H.E.; Dellacorte, C.; Lukaszewicz, V. |

    1995-07-01

    The Stirling space power machine incorporates a linear alternator to generate electrical power. The alternator is a reciprocating device that is driven by a solar or nuclear-powered Stirling engine. The power piston and cylinder are made of titanium 6A1-4V (Ti6-4) alloy, and are designed to be lubricated by a hydrodynamically-generated gas film. Rubbing occurs during starts and stops and there is a possibility of an occasional high speed rub. Since titanium is known to have a severe galling tendency in sliding contacts, a `backup,` self-lubricating coating on the cylinder and/or the piston is needed. This report describes the results of a research program to study the lubrication of Ti6-4 with the following chromium carbide based materials: plasma-sprayed PS212 coatings and sintered PM212 counterfaces. Program objectives are to achieve adherent coatings on Ti6-4 and to measure the friction and wear characteristics of the following sliding combinations under conditions simulative of the Stirling-driven space power linear alternator: Ti6-4/Ti6-4 baseline, Ti6-4/PS212 coated Ti6-4, and Ps212 coated Ti6-4/PM212

  13. RAMATION V=W Ot TOTS= t sAy VnoffZW COMM1 AV 10i90 2M3 AM=W V A CLSI~LL331M A1N2UW

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    t9, S. nTCmI RAMATION V=W Ot TOTS= t sAy VnoffZW COMM1 AV 10i90 2M3 AM=W V A CLSI~LL331M A1N2UW OMA1ID9 V3 WMM I~UMMIM UU &!% W 2W WT AM 0? ?Ml U&O(1 LW pAM Mr MMW31 T!WOLVSD A GUS =-o &L MCMA I h MMK ON PLUPCMTtft GJ DR P -M~ CAM~ 07 W ULOW~ M *!Ti ~~mum 0sflOY iftJ A SLXQT OUT (Wi M I M ra IJJW MarB~ *~ W? $MOM.~ HMP~ IT V=h MMOTM RW1& 07W O RAttcMUU w~A0AO wAf~ K 43)AN wA BE tluywxwD (b(6 l~U %I S~)6 ASSA~ r 6 AM MWOim~~ SUM v~ DM 'VAT M OM1 IN * M S W IMIEf To MIK Row.

  14. CX-001347: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    State Energy Program - Industrial Energy Efficiency GrantsCX(s) Applied: A8, A9Date: 03/15/2010Location(s): GeorgiaOffice(s): Energy Efficiency and Renewable Energy, National Energy Technology Laboratory

  15. CX-005054: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    Gas Hydrate Production Test (Phase III - Administrative/Planning/Modeling Tasks)CX(s) Applied: A2, A8, A9Date: 01/20/2011Location(s): Anchorage, AlaskaOffice(s): Fossil Energy, National Energy Technology Laboratory

  16. CX-002172: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    Aleutians East Borough Community Development CoordinatorCX(s) Applied: A8, A9, B5.1Date: 04/29/2010Location(s): Aleutians East Borough, AlaskaOffice(s): Energy Efficiency and Renewable Energy

  17. CX-012452: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    Design/Cost Study and Commercialization Analysis for Synthetic Jet Fuel Production CX(s) Applied: A8, A9, A11Date: 41877 Location(s): New JerseyOffices(s): National Energy Technology Laboratory

  18. CX-012459: Categorical Exclusion Determination

    Office of Energy Efficiency and Renewable Energy (EERE)

    Design/Cost Study and Commercialization Analysis for Synthetic Jet Fuel Production CX(s) Applied: A8, A9, A11Date: 41877 Location(s): PennsylvaniaOffices(s): National Energy Technology Laboratory

  19. CX-005883: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    Routine Monitoring, Maintenance, and Administrative Actions at the Salmon, Mississippi SiteCX(s) Applied: A8, A9, A11, B3.1Date: 05/05/2011Location(s): Salmon, MississippiOffice(s): Legacy Management

  20. CX-011714: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    Lightning Mapping Array Project CX(s) Applied: A8, A9, B3.1, B1.24 Date: 12/27/2013 Location(s): Texas Offices(s): Pantex Site Office

  1. CX-013480: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    Lightning Mapping Array Project - Amendment 2 CX(s) Applied: A8, A9, B1.24, B3.1Date: 03/18/2015 Location(s): TexasOffices(s): Pantex Site Office

  2. Microsoft Word - Attachment A-1 Performance Work Statement Amended...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... Perform andor coordinate maintenance activities and change combination-type safe locks, and maintain a supply of locksets, hardware, and spare parts and keys for immediate ...

  3. Search for B+ meson decay to a1+ K*0

    SciTech Connect (OSTI)

    del Amo Sanchez, P.; Lees, J.P.; Poireau, V.; Prencipe, E.; Tisserand, V.; Garra Tico, J.; Grauges, E.; Martinelli, M.; Palano, A.; Pappagallo, M.; Eigen, G.; Stugu, B.; Sun, L.; Battaglia, M.; Brown, D.N.; Hooberman, B.; Kerth, L.T.; Kolomensky, Yu.G.; Lynch, G.; Osipenkov, I.L.; Tanabe, T.; /UC, Berkeley /Birmingham U. /Ruhr U., Bochum /British Columbia U. /Brunel U. /Novosibirsk, IYF /UC, Irvine /UC, Riverside /UC, Santa Barbara /UC, Santa Cruz /Caltech /Cincinnati U. /Colorado U. /Colorado State U. /Dortmund U. /Dresden, Tech. U. /Ecole Polytechnique /Edinburgh U. /INFN, Ferrara /Ferrara U. /INFN, Ferrara /INFN, Ferrara /Ferrara U. /INFN, Ferrara /Frascati /INFN, Genoa /Genoa U. /INFN, Genoa /INFN, Genoa /Genoa U. /INFN, Genoa /INFN, Genoa /Genoa U. /Indian Inst. Tech., Guwahati /Harvard U. /Heidelberg U. /Humboldt U., Berlin /Imperial Coll., London /Iowa State U. /Iowa State U. /Johns Hopkins U. /Orsay, LAL /LLNL, Livermore /Liverpool U. /Queen Mary, U. of London /Royal Holloway, U. of London /Louisville U. /Mainz U., Inst. Kernphys. /Manchester U. /Maryland U. /Massachusetts U., Amherst /MIT /McGill U. /INFN, Milan /Milan U. /INFN, Milan /INFN, Milan /Milan U. /Mississippi U. /Montreal U. /INFN, Naples /Naples U. /NIKHEF, Amsterdam /Notre Dame U. /Ohio State U. /Oregon U. /INFN, Padua /Padua U. /INFN, Padua /INFN, Padua /Padua U. /Paris U., VI-VII /INFN, Perugia /Perugia U. /INFN, Pisa /Pisa U. /INFN, Pisa /Pisa, Scuola Normale Superiore /INFN, Pisa /Pisa U. /INFN, Pisa /Princeton U. /INFN, Rome /INFN, Rome /Rome U. /INFN, Rome /INFN, Rome /Rome U. /INFN, Rome /INFN, Rome /Rome U. /INFN, Rome /INFN, Rome /Rome U. /Rostock U. /Rutherford /DAPNIA, Saclay /SLAC /South Carolina U. /Southern Methodist U. /Stanford U., Phys. Dept. /SUNY, Albany /Tel Aviv U. /Tennessee U. /Texas U. /Texas U., Dallas /INFN, Turin /Turin U. /INFN, Trieste /Trieste U. /Valencia U. /Victoria U. /Warwick U. /Wisconsin U., Madison

    2011-08-11

    We present a search for the decay B{sup +} --> {alpha}{sup +}{sub 1}(1260)K*{sup 0}(892). The data, collected with the BABAR detector at the SLAC National Accelerator Laboratory, represent 465 million B{anti B} pairs produced in e{sup +}e{sup -} annihilation at the energy of the {Upsilon}(4S). We find no significant signal and set an upper limit at 90% confidence level on the product of branching fractions B(B{sup +} --> {alpha}{sup +}{sub 1}(1260)K*{sup 0}(892)) x B({alpha}{sup +}{sub 1}(1260) --> {pi}{sup +}{pi}{sup -}{pi}{sup +}) of 1.8 x 10{sup -6}.

  4. Exhibit A-1. Labor Categories and Occupation Codes

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Other 1 1 4 0.001 0.031 0.064 0.001 0.031 0.016 Thorium 15 5 27 0.067 0.052 0.096 0.004 ... 0.003 0.011 Plutonium 7 0.428 0.061 Thorium 10 0.128 0.013 Uranium 158 1.688 0.011 ...

  5. DOE/PPPO/03-0098&D1/A1

    Office of Environmental Management (EM)

    ... from blades, jagged metal, or splintering woodsiding Flying particles from metal, wood, ... medium (sand, glass beads, grit, or CO 2 pellets) suspended in an air spray to loosen and ...

  6. A-1 APPENDIX A DEFINITION OF TERMS AND ACRONYMS Acronyms

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    FFTF Fast Flux Test Facility FFS Focused Feasibility Study FS Feasibility Study GIS Geographic Information System (used on page G-2) GPM Gallons Per Minute GPS Global ...

  7. A-1 APPENDIX A DEFINITION OF TERMS AND ACRONYMS Acronyms

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of radioactive materials; each radionuclide has a characteristic constant half-life. Halogenated Hydrocarbons: Organic compounds containing atoms such as chlorine, fluorine,...

  8. Table A1: Tank Manufacturer Compatibility with Ethanol Blends

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    July 1, 1990) Lancaster Tanks and Steel Products Owens Corning (double ... wall since July 2005) Mid-South Steel Products, Inc. Xerxes (double wall ...

  9. Refrigerators and Refrigerator-Freezers (Appendix A1 after May...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    The Department of Energy (DOE) develops standardized data templates for reporting the results of tests conducted in accordance with current DOE test procedures. Templates may be ...

  10. Table A1. Total First Use (formerly Primary Consumption) of...

    U.S. Energy Information Administration (EIA) Indexed Site

    ... Manufacturing Industries"," W ",613,0," W ",2," W ",0,0," W ",0,28.1 ,"Total",1947,98827,2220,2397,500,6887,13448,1627,728,48,8.2 ,,"West South Central Census Division" ...