U.S. Department of Energy Office of Science Office of Scientific and Technical Information

Nobel Prize in Chemistry for seminal work related to ribosome, now a major target for new antibiotics

Ribosome
Venkatraman Ramakrishnan, Thomas A. Steitz, and Ada E. Yonath were awarded the 2009 Nobel Prize in Chemistry for their seminal research related to the ribosome's translation of DNA information into the code of life. All three conducted past research at DOE laboratories. The research by Ramakrishnan and Steitz was conducted in part at the National Synchrotron Light Source (NSLS) at Brookhaven National Laboratory. All three recipients published papers on their award-winning work based on data collected at DOE's Argonne National Laboratory. Ramakrishnan spent the early part of his career at the Oak Ridge National Laboratory High Flux Isotope Reactor. The three Laureates have all generated 3D models that show how different antibiotics bind to the ribosome. These models are now used by scientists in order to develop new antibiotics, directly assisting the saving of lives and decreasing humanity's suffering, according to the Nobel Laureate press release. View the feature and find Resources with Additional Information at DOE R&D Accomplishments, a central forum for information about the outcomes of past DOE R&D that have had significant economic impact, have improved people's lives, or have been widely recognized as remarkable advances in science.

Last updated on Friday 13 September 2013