Schnaufer, Achim - Institute of Immunology and Infection Research, University of Edinburgh

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• Evolution of dyskinetoplastic trypanosomes: how, and Achim Schnaufer
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• `My soul, sit thou a patient looker on; Judge not the play before the play is done
• Published online 15 January 2002 Composition of the editing complex
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• A Protein-Protein Interaction Map of the Trypanosoma brucei Paraflagellar Rod
• The cell cycle of Leishmania: morphogenetic events and their implications for parasite biologymmi_7479 647..662
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• Current Biology, Vol. 13, 598602, April 1, 2003, 2003 Elsevier Science Ltd. All rights reserved. DOI 10.1016/S0960-9822(03)00174-X -Tubulin Functions in the Nucleation
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• Molecular & Biochemical Parasitology 116 (2001) 2534 CAP5.5, a life-cycle-regulated, cytoskeleton-associated protein is a
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• in the snl-1 compared with wild-type cells. Western blots (Fig. 1b) of total cell lysates
• Molecular & Biochemical Parasitology 113 (2001) 7988 Diversity and dynamics of the minichromosomal karyotype in
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• Molecular and Biochemical Parasitology 94 (1998) 123126 Short communication
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• INTRODUCTION Trypanosomes are motile protozoans responsible for a variety
• The 14-3-3 Proteins of Trypanosoma brucei Function in Motility, Cytokinesis, and Cell Cycle*S
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• Molecular & Biochemical Parasitology 136 (2004) 113115 Short communication
• The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome
• The frequency of gene targeting in Trypanosoma brucei is independent of target site copy number
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• High Resolution Crystal Structure of a Key Editosome Enzyme from Trypanosoma brucei
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• Microtubule Polarity and Dynamics in the Control of Organelle Positioning, Segregation, and Cytokinesis in the Trypanosome Cell Cycle
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• Overview of the EBI We are the European Bioinformatics Institute (EBI), an
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• MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, Sept. 2003, p. 360375 Vol. 67, No. 3 1092-2172/03/$08.00 0 DOI: 10.1228/MMBR.67.3.360375.2003
• 1Edmund R.S. Kunji, Medical Research Council, Mitochondrial Biology Unit The Mitochondrial Carrier Family I
• Molecular Biology of the Cell Vol. 14, 17691779, May 2003
• Structural asymmetry and discrete nucleic acid subdomains in the Trypanosoma brucei kinetoplast
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• Invited Review The paraflagellar rod of kinetoplastid parasites: From structure to components
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• INTRODUCTION The eukaryotic flagellum can be regarded as a distinct
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• Molecular and Biochemical Parasitology 106 (2000) 2135 Cell-cycle and developmental regulation of TbRAB31
• Leishmania major chromosome 3 contains two long convergent polycistronic gene clusters separated by
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• ORIGINAL PAPER Achim Schnaufer Sandro Sbicego Beat Blum
• KREPA6 is an RNA-binding protein essential for editosome integrity and survival of Trypanosoma brucei
• PANDIT: an evolution-centric database of protein and associated nucleotide domains with inferred trees
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• The F1-ATP synthase complex in bloodstream stage trypanosomes has an unusual and essential
• Invited Review The biology of kinetoplastid parasites
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• Evidence for a Sliding-Resistance at the Tip of the Trypanosome Flagellum
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• Complex management: RNA editing in trypanosomes
• Killer toxin Protein (KP4): Harnessing the power of a
• Molecular Biology of the Cell Vol. 17, 17341743, April 2006
• Molecular & Biochemical Parasitology 119 (2002) 217223 A low-background inducible promoter system in Leishmania
• Limitation of Trypanosoma brucei parasitaemia results from density-dependent parasite
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• Blocking Variant Surface Glycoprotein Synthesis in Trypanosoma brucei Triggers a General Arrest in
• SURVEY AND SUMMARY Comparative analysis of editosome proteins in
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• 10.1101/gr.2227704Access the most recent version at doi: 2004 14: 1014-1024Genome Res.
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• Current Pharmaceutical Design, 2002, 8, 241-256 241 The Cell Biology of Parasitism in Trypanosoma brucei: Insights and Drug
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• Glucose is toxic to glycosome-deficient trypanosomes Tetsuya Furuya*
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• Inside and outside of the trypanosome flagellum: a multifunctional organelle
• A Protein-Protein Interaction Map of Trypanosome 20S Editosomes*S
• Invited review Natural and induced dyskinetoplastic trypanosomatids
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• Cytochrome c oxidase (complex IV) of respiratory chains
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• Mitochondrial DNA & Oxidative Phosphorylation ATP SYNTHASE
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• letters to nature NATURE |VOL 414 |13 DECEMBER 2001 |www.nature.com 759
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• Electron transfer mechanisms Dr. Judy Hirst
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• An essential role of KREPB4 in RNA editing and structural integrity of the editosome in Trypanosoma brucei
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• Functional Studies of an Evolutionarily Conserved, Cytochrome b5 Domain Protein
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• Molecular Biology of the Cell Vol. 15, 32573265, July 2004
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• Molecular & Biochemical Parasitology 132 (2003) 97100 Short communication
• A new function of Trypanosoma brucei mitochondrial topoisomerase II is to maintain kinetoplast DNA
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• The F0F1-ATP Synthase Complex Contains Novel Subunits and Is Essential for Procyclic Trypanosoma
• Variant surface glycoprotein RNA interference triggers a precytokinesis cell cycle arrest
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• Flagellar and Ciliary Beating in Trypanosome Motility
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• Molecular Evolution of FtsZ Protein Sequences Encoded Within the Genomes of Archaea, Bacteria, and Eukaryota
• The Expanded Kinesin-13 Repertoire of Trypanosomes Contains Only One Mitotic Kinesin Indicating Multiple
• Cytochrome bc1 complex Dr. Judy Hirst
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• The canonical `9+2' microtubule axoneme is the prin-cipal feature of many motile cilia and flagella and is
• Introduction Trypanosomatid parasites are the aetiological agents of several
• Gene Action and Cellular Function in Parasitic Protozoa Genomics and post-genomics in parasitology: genome babble or
• A Molecular Marker for Centriole Maturation in the Mammalian Cell Cycle Bodo M. H. Lange and Keith Gull
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• Identification of novel components of Trypanosoma brucei editosomes
• Abstract. The structural basis of mitosis, spindle organi-sation and chromosome segregation, in the unicellular
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• The Mitochondrial Carrier Family II Edmund RS Kunjihttp://www.mrc-mbu.cam.ac.uk/research/mitochondrial-carriers
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• Short communication Targeting of a tetracycline-inducible expression system to the
• Novel Naphthalene-Based Inhibitors of Trypanosoma brucei RNA Editing Ligase 1
• Combining RNA Interference Mutants and Comparative Proteomics to Identify Protein Components and
• Identification and characterization of two trypanosome TFIIS proteins exhibiting particular domain architectures
• Membrane domains and flagellar pocket boundaries are influenced by the cytoskeleton
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• Hostparasite interactions and trypanosome morphogenesis: a flagellar pocketful of goodies
• Analysis of the Trypanosome Flagellar Proteome Using a Combined Electron
• The trypanosome Sue Vaughan and Keith Gull*
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• 2006 Nature Publishing Group Flagellar motility is required for the viability of the
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• Evolutionary Relationships and Protein Domain Architecture in an Expanded Calpain Superfamily in Kinetoplastid Parasites
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• Molecular & Biochemical Parasitology 162 (2008) 112122 Contents lists available at ScienceDirect
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• Discovery of drug-like inhibitors of an essential RNA-editing ligase in Trypanosoma brucei
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• Complex I of respiratory chains Dr. Leonid Sazanov sazanov@mrc-dunn.cam.ac.uk
• Functional characterization of cohesin subunit SCC1 in Trypanosoma brucei and dissection of mutant phenotypes
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• The Mechanism of Complex I Dr. Judy Hirst
• Intracellular Positioning of Isoforms Explains an Unusually Large Adenylate Kinase Gene Family in the Parasite
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• Enigmatic Presence of Mitochondrial Complex I in Trypanosoma brucei Bloodstream Forms
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