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Denu, John - Molecular and Cellular Pharmacology Training Program & Department of Biomolecular Chemistry, University of Wisconsin at Madison
Research Focus Vitamin B3 and sirtuin function
Coenzyme Specificity of Sir2 Protein Deacetylases IMPLICATIONS FOR PHYSIOLOGICAL REGULATION*
Sir2 Protein Deacetylases: Evidence for Chemical Intermediates and Functions of a Conserved Histidine
Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases
Intramolecular Dephosphorylation of ERK by MKP3 Youngjoo Kim, Adrian E. Rice, and John M. Denu*,
Structure 14, 12071210, August 2006 2006 Elsevier Ltd All rights reserved DOI 10.1016/j.str.2006.07.004 Sirtuins Caught in the Act
SIRT1 Top 40 Hits: Use of One-Bead, One-Compound Acetyl-Peptide Libraries and Quantum Dots to Probe Deacetylase Specificity
Small molecule regulation of Sir2 protein deacetylases Olivera Grubisha1
Assays for mechanistic investigations of protein/histone acetyltransferases q
Substrate Specificity and Kinetic Mechanism of the Sir2 Family of -Dependent Histone/Protein Deacetylases
Mechanism of Nicotinamide Inhibition and Transglycosidation by Sir2 Histone/Protein Deacetylases*
Linking chromatin function with metabolic networks: Sir2 family of
Mechanism of Human SIRT1 Activation by Resveratrol* Received for publication, February 2, 2005
Probing the Transition-State Structure of Dual-Specificity Protein Phosphatases Using a Physiological Substrate Mimic
The Sir2 family of protein deacetylases John M Denu