- Mapping the Protein Phosphatase-2B Anchoring Site on AKAP79 BINDING AND INHIBITION OF PHOSPHATASE ACTIVITY ARE MEDIATED BY RESIDUES 315360*
- Molecular Cell, Vol. 3, 413422, April, 1999, Copyright 1999 by Cell Press Phosphorylation and Inactivation of BAD
- Full-length cardiac Na /Ca2 exchanger 1 protein is not phosphorylated by
- Regulation of the AKAP79-Protein Kinase C Interaction by /Calmodulin*
- ISSN: 1524-4571 Copyright 2010 American Heart Association. All rights reserved. Print ISSN: 0009-7330. Online
- Molecular Cell AKAP-Lbc Mobilizes a Cardiac
- AKAP signaling complexes: getting to the heart of the matter
- BioMed CentralBMC Neuroscience BMC Neuroscience2001,2 :17
- European Journal of Cell Biology 85 (2006) 621622 Contextual utilization of enzymes in discrete AKAP79/150 signalling
- Critical Review A-kinase Anchoring Proteins: From Protein Complexes to Physiology
- SUPPLEMENTAL DATA Supplemental Table 1. Quantitation of FRET by three different methods. Values are given as mean
- Neuropharmacology 46 (2004) 299310 www.elsevier.com/locate/neuropharm
- book reviews E14 NATURE CELL BIOLOGY VOL 4 JANUARY 2002 http://cellbio.nature.com
- The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways
- A-kinase-anchoring Lorene K. Langeberg and John
- Molecular Cell, Vol. 15, 889899, September 24, 2004, Copyright 2004 by Cell Press AKAP-Lbc Nucleates a Protein Kinase D
- Retrospective: Edwin G. Krebs (1918 2009)
- Proc. Natl. Acad. Sci. USA Vol. 94, pp. 1106711072, September 1997
- Organizing signal transduction through A-kinase anchoring proteins (AKAPs)
- AKAP79 Interacts with Multiple Adenylyl Cyclase (AC) Isoforms and Scaffolds AC5 and -6 to -Amino-3-hydroxyl-
- Proc. Nati. Acad. Sci. USA Vol. 88, pp. 2446-2450, March 1991
- Signaling Through Scaffold, Anchoring, and Adaptor Proteins
- MyRIP Anchors Protein Kinase A to the Exocyst Complex* Received for publication,June 22, 2007, and in revised form, August 28, 2007 Published, JBC Papers in Press,September 7, 2007, DOI 10.1074/jbc.M705167200
- THEJOURNALOF BIOLOGICALCHEMISTRY Q 1992by The American Societyfor Biochemistry and MolecularBiology,Inc.
- Cell Signaling in Space and Time: Where Proteins Come Together and
- Biochem. J. (2004) 381, 587592 (Printed in Great Britain) 587 ACCELERATED PUBLICATION
- The EMBO Journal Vol.17 No.8 pp.22612272, 1998 A novel lipid-anchored A-kinase Anchoring Protein
- Molecular Cell Integrating Cardiac PIP3 and cAMP Signaling
- Molecular Cell 24, 383395, November 3, 2006 2006 Elsevier Inc. DOI 10.1016/j.molcel.2006.09.006 Molecular Basis of AKAP Specificity
- THEJOURNALOF BIOLOGICALCHEMISTRY ( 0 1992 by The American Society for Biochemistryand Molecular Biology, Inc.
- pieces of information about that life have been irretrie-vably lost, yielding an under-determined landscape.
- AKAP79 and the evolution of the AKAP model Kimberley Dodge, John D. Scott*
- Neuron, Vol. 23, 423426, July, 1999, Copyright 1999 by Cell Press Modulation of Ion Channels: Minireview
- INTRODUCTION The classical picture of extracellular signals leading to a
- Regulation of ion channels by CAMP-dependent protein kinase and A-kinase anchoring proteins
- Compartmentalisation of phosphodiesterases and protein kinase A: opposites attract
- CK2 Phosphorylates SSRP1 and Inhibits Its DNA-binding Activity* Received for publication, December 10, 2004, and in revised form, January 14, 2005
- Brief Communication 321 Association of the type 1 protein phosphatase PP1 with the
- 2000 Macmillan Magazines Ltd 540 NATURE CELL BIOLOGY | VOL 2 | AUGUST 2000 | www.nature.com/ncb
- Proc. Natl. Acad. Sci. USA Vol. 94, pp. 1494214947, December 1997
- Targeted Protein Kinase A and PP-2B Regulate Insulin Secretion through Reversible Phosphorylation*
- Cell, Vol. 85, 912, April 5, 1996, Copyright 1996 by Cell Press Molecular Glue: Kinase Anchoring Minireview
- The A-kinase Anchoring Domain of Type II cAMP-dependent Protein Kinase Is Highly Helical*
- Electrostatic properties of the structure of the docking and dimerization domain of protein kinase A IIa
- Molecular Cell, Vol. 20, 661672, December 9, 2005, Copyright 2005 by Elsevier Inc. DOI 10.1016/j.molcel.2005.10.013 Spatial Restriction of PDK1 Activation
- Delineation of Type I Protein Kinase A-selective Signaling Events Using an RI Anchoring Disruptor*
- CompartmentalizationofCyclicAMPSignallingBiochemicalSocietyFocusedMeeting Compartmentalization of Cyclic AMP
- Communication Vol. 268, No. 28, Issue of October 5,pp. 20729-20732, 1993 THE JOWALOF B I O ~ I C A LCHEMISTRY
- Biochem. J. (1999) 343, 443452 (Printed in Great Britain) 443 Mechanism of A-kinase-anchoring protein 79 (AKAP79) and protein
- NGFInduction ofthe Metalloproteinase Transin/Stromelysin in PC12 Cells: Involvement ofMultiple Protein Kinases
- NATURE CELL BIOLOGY VOL 4 AUGUST 2002 http://cellbio.nature.com E203 Kinase-and phosphatase-anchoring
- Signaling Complexes : Junctions on the Intracellular Information Super
- Regulation of GluR1 by the A-Kinase Anchoring Protein 79 (AKAP79) Signaling Complex Shares Properties with Long-Term
- Carboxyl-terminal Phosphorylation Regulates the Function and Subcellular Localization of Protein Kinase C II*
- Neuron, Vol. 27, 107119, July, 2000, Copyright 2000 by Cell Press Targeting of PKA to Glutamate Receptors
- Targeting of Protein Kinase A by Muscle A Kinase-anchoring Protein (mAKAP) Regulates Phosphorylation and Function
- Dual Specificity A-kinase Anchoring Proteins (AKAPs) Contain an Additional Binding Region That Enhances Targeting of
- 2011LandesBioscience. Donotdistribute.
- INTRODUCTION The phosphorylation of intracellular proteins is a universal
- RAB32 MODULATES APOPTOSIS ONSET AND MITOCHONDRIA-ASSOCIATED MEMBRANE (MAM) PROPERTIES
- Loss of AKAP150 perturbs distinct neuronal processes Brian J. Tunquist*
- Molecular Cell Interaction with AKAP79 Modifies
- Molecular Biology of the Cell Vol. 16, 35743590, August 2005
- L E T T E R S AKAP-Lbc enhances cyclic AMP control of the ERK1/2
- The Rockefeller University Press, 0021-9525/99/12/1481/12 $5.00 The Journal of Cell Biology, Volume 147, Number 7, December 27, 1999 14811492
- -Dystrobrevin-1 recruits -catulin to the 1D-adrenergic receptor/dystrophin-associated
- BIOLOGY OF REPRODUCTION 58, 1496-1502 (1998) Regulation of Expression of A-Kinase Anchoring Proteins in Rat Granulosa Cells
- Signalling the Future 87 A-kinase-anchoring proteins and cytoskeletal
- 280:2038-2045, 2001.Am J Physiol Heart Circ Physiol Franck Potet, John D. Scott, Raha Mohammad-Panah, Denis Escande and Isabelle
- 2004 NaturePublishing Group Where and when enzymes become active have pro-
- The A-kinase anchoring protein Yotiao binds and regulates adenylyl cyclase in brain
- SUPPLEMENTARY INFORMATION Jarnss et al. "Splicing factor arginine serine rich 17A (SFRS17A) is an A-
- Biochem. J. (2006) 396, 297306 (Printed in Great Britain) doi:10.1042/BJ20051970 297 High-affinity AKAP7protein kinase A interaction yields novel protein
- Introduction Protein phosphorylation is a tightly regulated process that is
- H Y P O X I A mAKAP Compartmentalizes Oxygen-Dependent
- brief communications NATURE CELL BIOLOGY VOL 4 DECEMBER 2002 www.nature.com/naturecellbiology970
- 222 nature structural biology volume 6 number 3 march 1999 The molecular basis for
- THEJOURNALOF BIOLOGICALCHEMISTRY Q 1991by The American Society for Biochemistry and Molecular Biology, Inc
- Volume 302, number 3. 274-278 FEBS 11044 0 1992 Federation of European Biochemical Societies 00145793/92%5.00
- THEJOURNALOF BIOLOGICALC~enasnn 0 1994by TheAmerican Societyfor Biochemistry and Molecular Biology, Inc.
- 63 1994 by The Americen Society for Biochemistry and Molecular Biology, Inc. TNll d W R P i A t OF BlCIL~ICAl.CiiEWlSTRY Vol. 269,No.IO,issue of March 11, pp. 7658-7665,1994
- THE JOURNALOF BIOLOGICALCHEMISTRY 0 1994by The American Society for Biochemistry and Molecular Biology, Inc.
- Cloning and Characterization of a Novel A-kinase Anchoring Protein
- REVIEWS TIBS 21 -AUGUST 1996 Moreon targetwith protein
- Mutational Analysis of the A-Kinase Anchoring Protein (AKAP)-binding Site on RII
- Protein Kinase A Anchoring* Mark L. Dell'Acqua and John D. Scott
- Neuron, Vol. 19, 185196, July, 1997, Copyright 1997 by Cell Press cAMP-Dependent Regulation of Cardiac L-Type Ca2
- FunctionalAnchoringof the cAMP-DependentProteinKinase
- EXPERIMENTAL CELL RESEARCH 238, 305316 (1998) ARTICLE NO. EX973855
- 216 0962-8924/99/$ see front matter 1999 Elsevier Science. All rights reserved. trends in CELL BIOLOGY (Vol. 9) June 1999 PII: S0962-8924(99)01558-5
- DOI: 10.1126/science.285.5424.93 , 93 (1999);285Science
- Biochem. J. (1999) 344, 613623 (Printed in Great Britain) 613 Identification of cAMP-dependent protein kinase holoenzymes in preantral-
- Compartmentalization of kinases and phosphatases is a key determinant in the specificity of second messenger mediated
- Brief Communication 409 Assembly of an A kinase-anchoring protein2-adrenergic receptor
- Brief Communication 417 Pericentrin anchors protein kinase A at the centrosome through
- Regulation of Membrane Targeting of the G Protein-coupled Receptor Kinase 2 by Protein Kinase A and Its Anchoring
- Multiple Interactions within the AKAP220 Signaling Complex Contribute to Protein Phosphatase 1 Regulation*
- 281:958-965, 2001.Am J Physiol Renal Physiol Timothy G. Hammond and H. William Harris
- AKAP-Lbc Anchors Protein Kinase A and Nucleates G 12-selective Rho-mediated Stress Fiber Formation*
- Trafficking of L-type Calcium Channels Mediated by the Postsynaptic Scaffolding Protein AKAP79*
- The Rockefeller University Press, 0021-9525/2002/08/659/10 $5.00 The Journal of Cell Biology, Volume 158, Number 4, August 19, 2002 659668
- A-kinase anchoring protein 79/150 facilitates the phosphorylation of GABAA receptors by cAMP-dependent protein kinase via
- Induction of Flexibility through Protein-Protein Interactions* Received for publication, January 27, 2003, and in revised form, February 20, 2003
- A-kinase anchoring proteins and neuronal signaling mechanisms
- INTRODUCTION Extracellular signals, such as hormones, neu-
- Neuronal Microtubule-associated Protein 2D Is a Dual A-kinase Anchoring Protein Expressed in Rat Ovarian Granulosa Cells*
- Current Biology, Vol. 14, 14361450, August 24, 2004, 2004 Elsevier Ltd. All rights reserved. DOI 10.1016/j.cub.2004.07.051 Proteomic, Functional, and Domain-Based Analysis
- Role for A Kinase-anchoring Proteins (AKAPS) in Glutamate Receptor Trafficking and Long Term Synaptic Depression*
- A RT I C L E S 1066 NATURE CELL BIOLOGY VOLUME 7 | NUMBER 11 | NOVEMBER 2005
- This Review is part of a thematic series on Microdomains in Cardiovascular Signaling, which includes the following articles
- An anchored PKA and PDE4 complex regulates subplasmalemmal cAMP dynamics
- European Journal of Cell Biology 85 (2006) 585592 Anchored cAMP signaling: Onward and upward A short history of
- The where's and when's of kinase F. Donelson Smith, Lorene K. Langeberg and John D. Scott
- AKAP79-mediated Targeting of the Cyclic AMP-dependent Protein Kinase to the 1-Adrenergic Receptor Promotes
- Biochem. J. (2006) 400, 493499 (Printed in Great Britain) doi:10.1042/BJ20060962 493 Characterization of A-kinase-anchoring disruptors using
- A-kinase anchoring proteins take shape Darren L Beene and John D Scott
- AKAP18 Contains a Phosphoesterase Domain that Matthew G. Gold1
- www.sciencemag.org SCIENCE VOL 327 29 JANUARY 2010 537 PERSPECTIVES
- -Kinase Anchoring Proteins (AKAPs) orchestrate and synchronize cellular events by tethering the cAMP-dependent protein kinase (PKA) and other signaling enzymes to organelles and membranes. The
- 2010NatureAmerica,Inc.Allrightsreserved. nature structural & molecular biology advance online publication
- Rab32 Modulates Apoptosis Onset and Mitochondria-associated Membrane (MAM) Properties*
- Biochem. J. (2010) 432, 549556 (Printed in Great Britain) doi:10.1042/BJ20100936 549 PP2B/calcineurin-mediated desensitization of TRPV1 does not require
- Molecular Cell Chk-ing in and Chk-ing out
- Supporting Information Lyssand et al. 10.1073/pnas.1010819107
- Architecture and dynamics of an A-kinase anchoring protein 79 (AKAP79) signaling complex
- Supporting Information Gold et al. 10.1073/pnas.1014400108
- SUPPLEMENTARY MATERIAL 1. TALEEEIK
- Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology
- The Journal of Clinical Investigation | March 1999 | Volume 103 | Number 6 761 The issue of specificity in cellular signaling has attract-
- ISSN: 1524-4539 Copyright 2010 American Heart Association. All rights reserved. Print ISSN: 0009-7322. Online
- Dynamic Complexes of 2-Adrenergic Receptors with Protein Kinases and Phosphatases and the Role of Gravin*
- Splicing Factor Arginine/Serine-rich 17A (SFRS17A) Is an A-kinase Anchoring Protein That Targets Protein Kinase A to
- Section 4: -Cell Stimulus-Secretion Coupling: Metabolic Factors
- JCB: Article The Rockefeller University Press $30.00
- Spatial Distribution of Protein Kinase A Activity during Cell Migration Is Mediated by A-kinase Anchoring Protein AKAP Lbc*
- Molecular Cell 23, 925931, September 15, 2006 2006 Elsevier Inc. DOI 10.1016/j.molcel.2006.07.025 Short ArticleDynamic Regulation of cAMP
- 52 Research Paper Gravin, an autoantigen recognized by serum from myasthenia
- The EMBO Journal Vol.17 No.8 pp.22462260, 1998 Membrane-targeting sequences on AKAP79 bind
- Calcineurin anchoring and cell signaling Kimberly L. Dodge and John D. Scott*
- Proc. Nati. Acad. Sci. USA Vol. 83, pp. 1613-1616, March 1986
- THEJOURNALOF BIOLOGICALCHEMISTRY Q 1989by The American Society for Biochemistry and MolecularBiology,Inc. Vol. 26-4, No. 8,Issue of March 15, pp. 43744382 1989
- Proc. Natl. Acad. Sci. USA Vol. 84, pp. 5192-5196, August 1987
- Volume 246, number 1,2, 57-64 FEB 06943 March 1989 Human testis cDNA for the regulatory subunit RII of cAMP-
- THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 265, No. 35, Issue of December 15, pp. 21561-21566.1990 0 1990 by The American Society for Biochemistry and Molecular Biology, Inc.
- Proc. Nat!. Acad. Sci. USA Vol. 82, pp. 4379-4383, July 1985
- TIBS 17 -JULY 1992 Blotting and band-shifting:techniques
- Pharmac. Ther.Vol.50,pp. 123-145,1991 0163-7258/91$0.00+ 0.50 PrintedinGreatBritain 1991PergamonPressplc
- MOLECULAR AND CELLULAR BIOLOGY, Apr. 1987, p. 1371-1377 Vol. 7, No. 4 0270-7306/87/041371-07$02.00/0
- THE JOURNAL 0 1988by The AmericanSociety for Biochemistry
- BIOLOGY OF REPRODUCTION 43, 46-54 (1990) Subunits of Cyclic Adenosine 3', 5'-Monophosphate-Dependent Protein Kinase Show
- Biochem. J. (1982) 205,575-580 Printed in Great Britain
- Biochem. J. (2011) 438, 103110 (Printed in Great Britain) doi:10.1042/BJ20110720 103 Discovery of cellular substrates for protein kinase A using a peptide array
- Volume 229, number 2, 391-394 FEB 05673 March 1988 A unique mRNA species for a regulatory subunit of
- Anchored Protein Kinase A Recruitment of Active Rac Received for publication,February 17, 2011, and in revised form, March 28, 2011 Published, JBC Papers in Press,April 1, 2011, DOI 10.1074/jbc.M111.232660
- Proc. Nati. Acad. Sci. USA Vol. 82, pp. 5732-5736, September 1985
- Nieves-Cintrn, John D. Scott and Luis F. Santana Edward P. Cheng, Can Yuan, Manuel F. Navedo, Rose E. Dixon, Madeline
- 90 Brain Research, 520 (1990) 90-102 Immunocytochemical localization of the neural-specific regulatory
- AKAP220 ORGANIZES SIGNALING ELEMENTS THAT IMPACT CELL MIGRATION Jeremy S. Logue1,3
- 2011LandesBioscience. Donotdistribute.
- 268s BiochemmlSoclety Transacbions (1995)23 ANALYSIS OF A NOVEL A-KINASE ANCHORING
- John D. Scott and Luis F. Santana Manuel F. Navedo, Edward P. Cheng, Can Yuan, Scott Votaw, Jeffery D. Molkentin,
- AKAP220 Protein Organizes Signaling Elements That Impact Cell Migration*S
- An entirely specific type I A-kinase anchoring protein that can sequester two molecules
- BiochemicalSociety Transactions Subcellular targeting of kinases and phosphatases by association with bifunctional
- AKAP2 anchors PKA with aquaporin-0 to support ocular lens transparency
- Supplemental Information Molecular Cell, Volume 42
- SUPPLEMENTARY FIGURE LEGENDS Figure S1. RII overlay of lens fractions. Autoradiographs following 32
- Membrane SignallingComplexes I Wirnalawansa. S. J. (I 997) Crit. Rev. Neurobiol. I I, 167-239
- 210 Biochemical Society Transactions (2012) Volume 40, part 1 PKA phosphorylation of the small heat-shock
- Through a glass darkly James E. Hall
