Apkarian, A. Vania - Department of Physiology, Northwestern University

• A single PHN subject brain activityA single PHN subject brain activity for tactile stimulation in thefor tactile stimulation in the
• THE JOURNAL OF COMPARATIVE NEUROLOGY 308:467-490 (1991) Anatomic Evidence of Nociceptive Inputs
• This 3-dimensional graphic shows the abnormal rewiring of the brain's right hemisphere in
• BioMed Central Page 1 of 15
• Towards a theory of chronic pain A. Vania Apkarian a,b,
• Molecular Psychiatry (2000) 5, 482488 2000 Macmillan Publishers Ltd All rights reserved 1359-4184/00 $15.00
• A dorsolateral spinothalamic pathway in cat MARK W. JONES, CHARLES J. HODGE, Jr., A. VANIA APKARIAN and RICHARD T. STEVENS
• Fractals, Vol. 7, No. 1 (1999) 93103 c World Scientific Publishing Company
• Rob Kerr / The Bulletin Allison Suran of Healing Bridge Physical Therapy helps
• 81:2956-2963, 1999.J Neurophysiol Nikolaus M. Szeverenyi
• EAST DELAWARE STREET EAST CHESTNUT STREET
• Chemical Heterogeneity of the Living Human Brain: A Proton MR Spectroscopy Study on the Effects of Sex, Age, and Brain Region
• The Journal of Neuroscience, November 1994, 14(11): 6796-6614 Squirrel Monkey Lateral Thalamus. II. Viscerosomatic Convergent
• Pain and the brain: Specificity and plasticity of the brain in clinical chronic pain A. Vania Apkarian a,b,
• EXPERIMENTAL NEUROLOGY 85,202-208 ( 1984) RESEARCH NOTE
• ATTENUATION OF NEUROPATHIC MANIFESTATIONS BY LOCAL BLOCK OF THE ACTIVITIES OF THE VENTROLATERAL ORBITO-
• D-Cycloserine reduces neuropathic pain behavior through limbic NMDA-mediated circuitry q
• http://www.clarin.com/diario/2005/01/07/conexiones/t-899579.htm Un argentino propone estudiar el cerebro como una red similar a
• This work is driven by: A) recent theoretical developments in the area of nonlinear complex networks. It has been documented that disparate networks of interacting elements obey similar organizational principles. For example, in
• THE JOURNAL OF COMPARATIVE NEUROLOGY 288A47-473 (1989) PrimateSphothalamicPathways
• 220 The Journal of Pain, Vol 2, No 4 (August), 2001: pp 220-228 eripheral nerve injuries, resulting from either per-
• J Neural Transm (2002) 109: 1533 Multi-chemical networking profile of the living human brain
• NeuroscienceLetters, 140(1992)141 147 141 1992ElsevierScientificPublishersIrelandLtd.All rightsreserved0304-3940/92/$05.00
• Cognitive Brain Research 11 (2001) 185197 www.elsevier.com/locate/bres
• Electrode Implantation and SNI Surgery Male Sprague-Dawley rats (225-250 grams) were anesthetized using isofluorane 5%,
• Behavioral/Systems/Cognitive Chronic Back Pain Is Associated with Decreased Prefrontal
• Efficient distributed algorithms for pattern detection in graphs derived from fMRI measurements
• BrainResearch, 336(1985)243-251 243 Funicular Course of Catecholamine Fibers Innervating the Lumbar
• Open to the public Faculty/staff only
• Available online at www.sciencedirect.com Pain perception in relation to emotional learning
• Imaging the pain of low back pain: functional magnetic resonance imaging in combination with monitoring subjective pain perception
• Old Antibiotic Gets New Life in Modern Medicine For a half-century, D-cycloserine has led a quiet, workmanlike existence as an antibiotic, primarily for
• Journal of NeuroscienceMethods, 45 (1992)35-40 35 1992Elsevier Science Publishers B.V. All rights reserved 0165-0270/92/$05.00
• Brain dynamics for perception of tactile allodynia (touch-induced pain) in postherpetic neuralgia
• Journal of Neuroscience Methods, 29 (1989) 93-106 93 Research Papers
• One patient suffering from chronic arthritis was tested. Prior to
• 88:2096-2103, 2002.J Neurophysiol Vasco Galhardo, A. Vania Apkarian and Deolinda Lima
• Clinical Study The Brain in Chronic CRPS Pain
• Chronic pain patients are impaired on an emotional decision-making task A. Vania Apkariana,*, Yamaya Sosaa
• Pain intensity ratings were significantly reduced after the
• Brain activity for spontaneous pain of postherpetic neuralgia and its modulation by lidocaine patch therapy
• Neuroscience Letters 441 (2008) 145148 Contents lists available at ScienceDirect
• Bruin Research, 555 (1991) 10-in 1991 Elsevier Science Publishers B.V. All rights reserved. I)006-8993/91/$03.50
• Brain activity for chronic knee osteoarthritis: Dissociating evoked pain from spontaneous pain
• Increased taste intensity perception exhibited by patients with chronic back pain
• High -low (PH-L VH-L SH-L) Activity is present in the medial and lateral orbital prefrontal
• Neuroseienee Letters, 160 (1993) 209 213 209 1993Elsevier Scientific Publishers Ireland Ltd. All fights reser'/ed 0304-3940/93/$ 06.00 -
• Cancer Detection and Prevention 26 (2002) 192196 Mastalgia and breast cancer: a protective association?
• Functional imaging of pain: new insights regarding the role of the cerebral cortex in human pain perception
• Breast Pain Questionnaire Name: Ethnicity (optional): Birthdate
• Prefrontal cortex and spinal cord mediated anti-neuropathy and analgesia induced by sarcosine, a glycine-T1 transporter inhibitor q
• Morphological and functional reorganization of rat medial prefrontal cortex in neuropathic pain
• J Neurophysiology Parsing pain perception between nociceptive
• BioMed Central Page 1 of 12
• Beneficial Effects of Hematopoietic Growth Factor Therapy in Chronic Ischemic Stroke in Rats
• Spontaneous Pain and Brain Activity in Neuropathic Pain: Functional MRI and
• Behavioral/Systems/Cognitive Chronic Pain and the Emotional Brain: Specific Brain
• The shadows of pain A major roadblock in understanding pain mecha-
• Chronicpainremainsoneofthemostindomitablemedical, biological and social challenges today. During the last
• 95:730-736, 2006. First published Nov 9, 2005; doi:10.1152/jn.00768.2005J Neurophysiol Jennifer M. Foss, A. Vania Apkarian and Dante R. Chialvo
• BioMed Central Page 1 of 8
• Brain Imaging Findings in Neuropathic Pain
• BioMed Central Page 1 of 13
• Cortical pathophysiology of chronic pain
• THE ROLE OF THE DORSAL COLUMNS IN NEUROPATHIC BEHAVIOR: EVIDENCE FOR PLASTICITY AND NON-SPECIFICITY
• DOI 10.1007/s00702-002-0722-7 J Neural Transm (2002) 109: 13091334
• Breast Cancer Research and Treatment 75: 147157, 2002. 2002 Kluwer Academic Publishers. Printed in the Netherlands.
• Prefrontal cortical hyperactivity in patients with sympathetically mediated chronic pain
• Molecular Psychiatry (2001) 6, 256260 2001 Nature Publishing Group All rights reserved 1359-4184/01 $15.00
• Chemical Mapping of Anxiety in the Brain of Healthy Humans: An in vivo 1
• 83:3113-3122, 2000.J Neurophysiol A. Vania Apkarian, Patricia A. Gelnar, Beth R. Krauss and Nikolaus M.
• A Comparative fMRI Study of Cortical Representations for Thermal Painful, Vibrotactile, and Motor Performance Tasks
• Fingertip Representation in the Human Somatosensory Cortex: An fMRI Study
• THE JOURNAL OF COMPARATIVE NEUROLOGY 365~640-658(1996) Direct Spinal Projectionsto Limbic and
• THE JOURNAL OF COMPARATIVE NEUROLOGY 361:1-24 (1995) Morphology of Thalamocortical Neurons
• Heat-Induced Pain Diminishes Vibrotactile Perception: A Touch Gate
• JOURNALOFNEUROPHYSIOLOGY Vol. 64, No. 5, November 1990. Printed in U.S.A.
• THE JOURNAL OF COMPARATIVE NEUROLOGY 288493-511 (1989) Primate SpinothalamicPathways:III.
• THE JOURNAL OF COMPARATIVE NEUROLOGY 288:474-492 (1989) PrimateSpinothalamic Pathways:II. The
• EXPERIMENTAL NEUROLOGY 90, 2i 5-223 (1985) Sources of the Catecholaminergic Innervation of the
• Brain Research, 261 (1983) 151-154 151 Elsevier Biomedical Press
• IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, VOL. BME-30, NO. 2, FEBRUARY 1983 which saved about 40 percent of computing time (van Ooste-
• Brain Research, 239 (1982) 589-594 589 Elsevier Biomedical Press
• Brain Research, 204 (1981)415-420 415 Elsevier/North-Holland BiomedicalPress
• Neuropathic Pain Modulates Hippocampus Mediated Emotional Behavior
• Chronic pain and the perceived value of monetary reward E. L. PARKS1, A.T. BARIA, M. N. BALIKI1, *A.V. APKARIAN1, 2
• A double-blind, placebo-controlled study of the effects of lidocaine patch therapy on brain activity for spontaneous pain
• Nucleus accumbens responses to painful aversive and rewarding stimuli change in chronic pain
• We used spared nerve injury (SNI) model to assess effects of sarcosine in adult, male, Sprague Dawley
• Neuropathic pain can lead to depression, insomnia, depressed immune function, changes in eating patterns, and
• Fractional Anisotropy of White Matter Tract Contrasted between Complex Regional Pain Syndrome and Normal Controls
• INTRODUCTION Psychological theories and recent imaging
• We explore two new automated methods to quantify the impact of pain on the overall
• INTRODUCTION We used spared nerve injury (SNI)
• INTRODUCTION Dynamics of Pain perception: Distinctive Features of Ongoing Chronic Pain Ratings Revealed By Nonlinear Analysis
• Supported by NIH NINDS NS 35115 (AVA) and NIA AG00940 (DRG)
• Bennett and Xie (Pain 33: 87, 1988) Chronic Constrictive Injury Model
• Search RSDSA This graphic illustrates the abnormal
• Public release date: 26-Nov-2008 [ Print Article | E-mail Article | Close Window ]
• Nationwide News Old Antibiotic May Be Used
• How Chronic Pain Gets Into Your Head Page 1 of 3 http://www.abcnews.go.com/print?id=4249610
• Public release date: 5-Feb-2008 [ Print Article | E-mail Article | Close Window ]
• Best Life Magazine A growing cadre of doctors and scientists now believes that chronic b... Page 1 of 6 http://www.bestlifeonline.com/cms/publish/health-fitness/The_Psychology_of_Back_Pain_...
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• FEBRUARY 28, BACK PAIN BRAIN 02.15.05
• http://msnbc.msn.com/id/6787415/ HOW YOUR BRAIN IS LIKE THE INTERNET
• http://weblog.educ.ar/educacion-tics/ La dinmica de los sistemas complejos: pjaros,
• &in, 37 (1989) 323-333 Basic Section
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• UCI chemistry center awarded $20 million from NSF
• P.6/11NO.867NU OPRS (IRE ACUC)3: 39PMAUG.10.2000 NORTHWESTERN UNIVERSITY
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• Brain Research, 631 (1993) 241-246 241 1993 Elsevier Science Publishers B.V. All rights reserved 0006-8993/93/$06.00
• PALO ALTO, CALIFORNIA--Ready or not, neuro-imaging is knocking on the courthouse door.
• Journal of Neurochemistry, 2001, 77, 292303 Aging alters the multichemical networking prole of the human
• Funicular location of ascending axons of lamina I cells in the cat spinal cord A. VANIA APKARIAN, RICHARD 1. STEVENS and CHARLES J. H()DGI-
• The mechanisms underlying chronic osteoarthritis (OA) pain remain obscure.
• BioMed Central Page 1 of 10
• INTRODUCTION We have reported in previous studies that
• Correspondence: Stanley J. Bolanowski, Institute for Sensory Research, Syracuse University, Syracuse, NY 13244 5290, USA. Tel.: (315) 443 4164; Fax: (315) 443 1184; E-mail: sandy_bolanowski@isr.syr.edu
• J Neurosurg 65:825-833, 1986 Inhibition of dorsal-horn cell responses by stimulation of
• Research Papers Abnormal brain chemistry in chronic back pain: an in vivo proton
• Gray matter densities in CBP were determined VBM analysis using the SPM 99 package. A
• JOURNALOF NEUROPHYSIOLOGY Vol. 50, No. 5, November 1983. Printed
• Functional Magnetic Resonance Imaging of Pain Consciousness
• 79:1879-1890, 1998.J Neurophysiol Chandra Ivey, A. Vania Apkarian and Dante R. Chialvo
• Brief Communications Beyond Feeling: Chronic Pain Hurts the Brain, Disrupting
• BrainResearch,288(1983)325-329 325 Changes in the effects of stimulation of locus coeruleus and nucleus raphe
• A wiring rule for the insula based on DTI A.T. Baria, M.N. Baliki, E.L. Parks, A.V. Apkarian
• Z .Brain Research 756 1997 297300 Short communication
• DRUG DISCOVERY Shared mechanisms between chronic
• Human brain mechanisms of pain perception and regulation in health and disease
• Topical review Cortical representation of pain: functional characterization of nociceptive
• Chronic Pain Harms The Brain ScienceDaily (Feb. 6, 2008) --People with
• 0 100 200 300 400 500 600 spontaneous ongoing pain rating
• Segregation of Nociceptive and Non-Nociceptive Networks in the Squirrel Monkey Somatosensory Thalamus
• Neuroscience Letters 407 (2006) 176181 Expression of IL-1 in supraspinal brain regions
• The Journal of Neuroscience. November 1994, 14(11): 6779-9795 Squirrel Monkey Lateral Thalamus. I. Somatic Nociresponsive
• Our recent fMRI studies indicate that spontaneous chronic back-pain (CBP) is
• Predicting Value of Pain and Analgesia: Nucleus Accumbens Response to Noxious Stimuli
• Heat hyperalgesiaHeat hyperalgesia TIME (days)
• Scale-Free Brain Functional Networks Victor M. Eguiluz,1
• -5 0 5 10 15 20 25 30 -5 0 5 10 15 20 25 30
• THE JOURNAL OF COMPARATIVE NEUROLOGY 260:349-361(1987) The Spinothalamic Tract
• Page 1 of 2 http://uk.reuters.com/articlePrint?articleId=UKN0521570320080205
• Z .Brain Research 787 1998 269276 Research report
• background Na+ conductance in pacemaking activity is unproven,
• JOURNALOF NEUROPHYSIOLOGY Vol. 66, No. 1, July 1991. Printed in U.S.A.
• ResultsIntroduction Animals & surgery: Two sets of Wistar-Kyoto
• Brain Activity for Osteoarthritis Pain : an fMRI Study M.V. Centeno1, P.Y.Geha1, A.V. Apkarian1, J.A. Katz2, M.N. Baliki1, D.R. Chialvo1
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• 1 Remembering forward: Neural correlates of memory and prediction in human 2 motor adaptation
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• Brain Functional and Anatomical Changes in Chronic Prostatitis/Chronic Pelvic Pain Syndrome
• Adult Children of Aging Parents
• Trim: 247mm 174mm Top: 12.653mm Gutter: 16.871mm CUUK1505-10 CUUK1505/Seth ISBN: 978 1 107 00049 0 June 23, 2011 11:19
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• to eating high-caloric foods that can promote obesity. The findings bode well for a strategy of
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• Pain Characteristic Differences Between Subacute and Chronic Mona Lisa Chanda,* Matthew D. Alvin,y
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• DOI 10.1007/s10071-009-0226-z ORIGINAL PAPER
• MOLECULAR NEUROSCIENCE HYPOTHESIS ANDTHEORY ARTICLE
• Abstract Rapid reaching movements of human and non-human primates are often characterized by irreg-
• Behavioral/Systems/Cognitive The Cortical Rhythms of Chronic Back Pain
• NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health. Kruger L, Light AR, editors. Translational Pain Research: From Mouse to Man. Boca Raton, FL: CRC Press;
• Remembering forward: Neural correlates of memory and prediction in human motor adaptation
• Differential effects of paced and unpaced responding on delayed serial order recall in schizophrenia
• NATURE REVIEWS | UROLOGY VOLUME 8 | JULY 2011 Nature Reviews Urology 8, 352 (2011); doi:10.1038/nrurol.2011.93
• 0892-6638/88/0002-0097/$01 .50. FASEB 97 Control strategies in physiological systems
• Action selection and refinement in subcortical loops through basal
• Chronic neuropathic pain-like behavior correlates with IL-1b expression and disrupts cytokine interactions in the hippocampus
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• Brain Morphological Signatures for Chronic Pain Marwan N. Baliki1