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- 2000 Macmillan Magazines Ltd 326 NATURE CELL BIOLOGY | VOL 2 | JUNE 2000 | www.nature.com/ncb
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- Copyright 2006 by the Genetics Society of America DOI: 10.1534/genetics.106.061580
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- 23. Pandori, M. W. et al. Producer-cell modication of human immunodeciency virus type 1: Nef is a virion protein. J. Virol. 70, 42834290 (1996).
- The Rockefeller University Press, 0021-9525/2001/05/1011/11 $5.00 The Journal of Cell Biology, Volume 153, Number 5, May 28, 2001 10111021
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