Dustin, Michael - Skirball Institute of Biomolecular Medicine, New York University

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Dustin, Michael - Skirball Institute of Biomolecular Medicine, New York University

Relative Contribution of LFA-1 and Mac-1 to Neutrophil Adhesion and Migration1
What is the importance of the immunological synapse?
CUTTING EDGE Cutting Edge: Activation by Innate Cytokines or
Nanoscale increases in CD2-CD48 mediated intermembrane spacing decrease adhesion and reorganize the immunological
Immunity, Vol. 16, 839848, June, 2002, Copyright 2002 by Cell Press Immature CD4 CD8 Thymocytes
/ www.sciencexpress.org / 10 March 2011 / Page 1 / 10.1126/science.1199214 The growth factor progranulin (PGRN) has been
Germinal Center Dynamics Revealed by Multiphoton Microscopy with a
doi:10.1182/blood-2010-05-283770 Prepublished online Nov 2, 2010;
Signaling microdomains in T cells Kaushik Choudhuri, Michael L. Dustin
HIV-1 Virological Synapse is not Simply a Copycat of the Immunological Synapse
2010;2:a002311 originally published online September 15, 2010Cold Spring Harb Perspect Biol Michael L. Dustin, Arup K. Chakraborty and Andrey S. Shaw
Development and Migration of Plasma Cells in the Mouse Lymph Node
24 Published 2010. This article is a US Government work and is in the public domain in the USA Immunological Reviews 235/2010 Michael L. Dustin
C o m m e n t a r y The Rockefeller University Press $30.00
/ www.sciencexpress.org / 25 March 2010 / Page 1 / 10.1126/science.1186068 T cell receptor (TCR) dependent regulatory T cell (Treg)
Kinetics of Early T Cell Receptor Signaling Regulate the Pathway of Lytic Granule Delivery
JOURNAL OF VIROLOGY, Nov. 2009, p. 1134111355 Vol. 83, No. 21 0022-538X/09/$12.00 doi:10.1128/JVI.01440-09
Galectin-3 negatively regulates TCR-mediated CD4 T-cell activation at the immunological synapse
(66), mr4. [DOI: 10.1126/scisignal.266mr4]2Science Signaling Michael L. Dustin (14 April 2009)
Fax +41 61 306 12 34 E-Mail karger@karger.ch
TrCP-and Rsk1/2-mediated degradation of BimEL inhibits Elinor Dehan1, Florian Bassermann1, Daniele Guardavaccaro1,*, Gaia Vasiliver-Shamis1,
Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis
Spatiotemporal Regulation of T Cell Costimulation by TCR-CD28 Microclusters
Protein Kinase C Regulates Stability of the Peripheral Adhesion Ring Junction and Contributes to the Sensitivity of
Modulation of T Cell Activation by Stomatin-Like Mark G. Kirchhof,* Luan A. Chau,* Caitlin D. Lemke,* Santosh Vardhana,
JOURNAL OF VIROLOGY, Oct. 2008, p. 94459457 Vol. 82, No. 19 0022-538X/08/$08.00 0 doi:10.1128/JVI.00835-08
Leading Edge Cell 132, March 7, 2008 2008 Elsevier Inc. 733
Tug of War at the Exit Door Michael L. Dustin1,* and Arup K. Chakraborty2,3,4,*
Cell adhesion molecules and actin cytoskeleton at immune synapses and kinapses
Quantification and Modeling of Tripartite CD2-, CD58FC Chimera (Alefacept)-, and CD16-mediated Cell Adhesion*
Requirements for T Lymphocyte Migration in Explanted Lymph Nodes1
Control of Antigen Presentation with a Photoreleasable Agonist Peptide Andrew L. DeMond,, Toby Starr, Michael L. Dustin, and Jay T. Groves*,,
Immunity 25, 117127, July 2006 2006 Elsevier Inc. DOI 10.1016/j.immuni.2006.04.010 T Cell Receptor-Proximal Signals Are Sustained
CREDIT:P.HUE/SCIENCE An excess of a protein that regulates actin
T cells like a firm molecular handshake Michael L. Dustin*
T celldendritic cell immunological synapses Michael L Dustin, Su-Yi Tseng, Rajat Varma and Gabriele Campi
*Lymphocyte Biology Section, Laboratory of
20. M. B. Beard et al., J. Biol. Chem. 275, 10349 (2000). 21. A. McCahill et al., Cell. Signal. 17, 1158 (2005).
CD80 Cytoplasmic Domain Controls Localization of CD28, CTLA-4, and Protein Kinase C in the
Immunity, Vol. 21, 305314, September, 2004, Copyright 2004 by Cell Press ReviewStop and Go Traffic
Immunity, Vol. 20, 589599, May, 2004, Copyright 2004 by Cell Press LFA-1/ICAM-1 Interaction Lowers
CCD = charge-coupled device; FIAU = 2-fluoro-2-deoxy-1-beta-D-arabinofuranosyl-5-iodo-uracil; HSV-Tk = herpes simplex virus thymidine kinase; MHC = major histocompatibility complex; MRI = magnetic resonance imaging; PET = positron emission tomography.
Stimulation of naive T-cell adhesion and immunological synapse formation by chemokine-dependent and -independent mechanisms
Immunity, Vol. 16, 193204, February, 2002, Copyright 2002 by Cell Press WIP Deficiency Reveals a Differential
The stable immunological synapse between a T cell and antigen-presenting cell coordinates migration and activation.
Cell, Vol. 103, 283294, October 13, 2000, Copyright 2000 by Cell Press Signaling Takes Shape in Review
seminars in IMMUNOLOGY, Vol 12, 2000: pp. 5 21 doi: 10.1006rsmim.1999.0203, availableonlineat http:rrwww.idealibrary.com on
K. P. Mullane-Robinson, N. L. Lill, P. Douillard, H. Band, J. Biol. Chem. 274, 16619 (1999).
Micropatterning of costimulatory ligands enhances CD4 T cell function
Force as a Facilitator of Integrin Conformational Changes during Leukocyte Arrest on Blood
ANRV406-IY28-04 ARI 29 October 2009 16:25 Functional Anatomy
TheJournalofExperimentalMedicine BRIEF DEFINITIVE REPORT
Cutting Edge: Quantitative Imaging of Raft Accumulation in the Immunological Synapse
to phospho-p44/p42 MAPK (Thr202 ) (1:5000),
T cell antigen receptor signaling and immunological synapse stability require myosin IIA
Nave T cell activation requires the interactions of antigen receptors, adhesion molecules and co-stimulatory molecules.
The Journal of Clinical Investigation | January 2004 | Volume 113 | Number 1 49 Introduction
Molecular Biology of the Cell Vol. 20, 37833791, September 1, 2009
The Journal of Clinical Investigation | January 2002 | Volume 109 | Number 2 155 PERSPECTIVE SERIES
37. B. Aravamudan, T. Fergestad, W. S. Davis, C. K. Ro-desch, K. Broadie, Nature Neurosci. 2, 965 (1999).
The Cellular Context of T Cell Signaling Michael L. Dustin1,*
The Rockefeller University Press $30.00 J. Exp. Med.
Innate Response to Focal Necrotic Injury Inside the Blood-Brain Barrier1
TheJournalofExperimentalMedicine JEM The Rockefeller University Press $8.00
T Cell-Dendritic Cell Immunological Synapses Contain TCR-dependent CD28-CD80 Clusters That Recruit Protein
Integrin-Dependent Organization and Bidirectional Vesicular Traffic at Cytotoxic Immune Synapses
CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia
1783 J. Exp. Med. The Rockefeller University Press 0022-1007/99/12/1783/10 $5.00 Volume 190, Number 12, December 20, 1999 17831792
Molecular Membrane Biology, 2010; Early Online, 112 High plasma membrane lipid order imaged at the immunological
Research paper Two-photon laser scanning microscopy imaging of intact spinal cord and
L E T T E R S The lymphocyte function-associated antigen-1
of May 10, 2010 This information is current as
see commentary on page 412 interstitial dendritic cells form a contiguous
self and viral antigens that augment the T cell response Quantum dot/peptide-MHC biosensors reveal strong CD8-dependent cooperation between
The Rockefeller University Press $30.00 J. Exp. Med.
Cutting Edge: Hierarchy of Chemokine Receptor and TCR Signals Regulating
A supramolecular basis for CD45 tyrosine phosphatase regulation in sustained
THEJOURNALOF BIOIXICALC H E M I ~ Y 0 1994 by The American Societyfor Biochemistryand Molecular Biology, Inc.
Essential Role of Ubiquitin and TSG101 Protein in Formation and Function of the Central
Dynamic Imaging of the Effector Immune Response to Listeria Infection In Vivo
HIV-1 envelope gp120-induced partial T-cell receptor signaling creates an F-1 actin-depleted zone in the virological synapse2
T Cell Receptor Microcluster Transport through Molecular Mazes Reveals Mechanism of Translocation
Ann. N.Y. Acad. Sci. 987: 5159 (2003). 2003 New York Academy of Sciences. Coordination of T Cell Activation and
http://immunol.nature.com july 2000 volume 1 no 1 nature immunology 23 Michael L. Dustin1
UNCORRECTED 3 Supported bilayers at the vanguard of immune cell activation studies
Supported planar bilayers in studies on immune cell adhesion and communication
Polar Redistribution of the Sialoglycoprotein CD43: Implications for T Cell Function1
Lateral Membrane Waves Constitute a Universal Dynamic Pattern of Motile Cells Hans-Gunther Dobereiner,1,* Benjamin J. Dubin-Thaler,1
JCB: ARTICLE The Rockefeller University Press $30.00
Endothelial Cell Apoptotic Genes Associated with the Pathogenesis of Thrombotic Microangiopathies
Two-photon laser scanning microscopy imaging of intact spinal cord and cerebral cortex reveals requirement for CXCR6 and neuroinflammation in immune cell infiltration of
Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes
Opposing Effects of PKCq and WASp on Symmetry Breaking and Relocation
A Biophysical Model of Cell Adhesion Mediated by Immunoadhesin Drugs and Antibodies
T-cell triggering thresholds are modulated by the number of antigen within individual
HIV Envelope gp120 Activates LFA-1 on CD4 T-Lymphocytes and Increases Cell Susceptibility to
PKC-u function at the immunological synapse: prospects for therapeutic
The Rockefeller University Press $30.00 J. Exp. Med. Vol. 208 No. 8 1695-1705
Boltzmann Energy-based Image Analysis Demonstrates that Extracellular Domain Size Differences Explain
doi:10.1182/blood-2011-01-331272 Prepublished online June 7, 2011;
The T cell synapse is an ultrasensitive system capable of detecting single peptideMHC complexes1