- Design and Synthesis of Novel Inhibitors of Gelatinase B Xueqing Wang,a
- Therapeutics, Targets, and Chemical Biology Tumor Detection by Imaging Proteolytic Activity
- 1784 J. Am. Chem. SOC.1992, 114, 1784-1790 ( ~ B u ) ~ N Fin THF. The products of 9-11 were analyzed by 'H and I3C
- Biochemistry 1992, 31, 3059-3064 3059 Perturbing the Polar Environment of Asp102 in Trypsin: Consequences of
- Structure of an FabProtease Complex Reveals a Highly Specific Non-canonical Mechanism of Inhibition
- Improving the species cross-reactivity of an antibody using computational design
- Inhibition of a Secreted Glutamic Peptidase Prevents Growth of the Fungus Talaromyces emersonii*
- One Functional Switch Mediates Reversible and Irreversible Inactivation of a Herpesvirus Protease
- The Prostate 62:1^13 (2005) Substrates ofthe Prostate-Specific Serine Protease
- Substrate Specificity Profiling and Identification of a New Class of Inhibitor for the Major Protease of the SARS Coronavirus,
- 2616 Biochemistry 1987, 26, 2616-2623 Selective Alteration of Substrate Specificity by Replacement of Aspartic Acid-189
- JOURNAL OF VIROLOGY, June 2004, p. 66576665 Vol. 78, No. 12 0022-538X/04/$08.00 0 DOI: 10.1128/JVI.78.12.66576665.2004
- Biochem. J. (2003) 371, 525532 (Printed in Great Britain) 525 Catalytic properties and inhibition of proline-specific dipeptidyl peptidases II,
- A Multi-enzyme Cascade of Hemoglobin Proteolysis in the Intestine of Blood-feeding Hookworms*
- Biochem. J. (2004) 378, 529538 (Printed in Great Britain) 529 Identification and biochemical characterization of vivapains, cysteine
- The CD8 cell noncytotoxic anti-HIV response can be blocked by protease inhibitors
- Chemistry & Biology Peptide Length and Leaving-Group Sterics Influence
- THE OLIGOPEPTIDASE B OF LEISHMANIA REGULATES PARASITE ENOLASE AND IMMUNE EVASION*
- Expedient Solid-Phase Synthesis of Fluorogenic Protease Substrates Using the 7-Amino-4-carbamoylmethylcoumarin (ACC)
- Selective Inhibition of the Collagenolytic Activity of Human Cathepsin K by Altering Its S2 Subsite Specificity
- Biol. Chem., Vol. 391, pp. 333343, April 2010 Copyright by Walter de Gruyter Berlin New York. DOI 10.1515/BC.2010.044 Article in press -uncorrected proof
- The Mechanism of Inhibition of Antibody-based Inhibitors of Membrane-type Serine Protease 1 (MT-SP1)
- 452. Trypsin MEROPS name: Trypsin 1 (tetrapod, non-human)
- Functional Consequences of the Kaposi's Sarcoma-Associated Herpesvirus Protease Structure: Regulation of Activity and Dimerization by Conserved Structural
- Identification of the Major Cysteine Protease of Giardia and Its Role in Encystation*S
- A Parasite Cysteine Protease Is Key to Host Protein Degradation and Iron Acquisition*S
- Adhesion signaling by a novel mitotic substrate of src kinases Ami S Bhatt1
- Specificity Profiling of Seven Human Tissue Kallikreins Reveals Individual Subsite Preferences*
- Time-Resolved Single-Step Protease Activity Quantification Using
- Scanning the Prime-Site Substrate Specificity of Proteolytic Enzymes: A Novel Assay Based on Ligand-Enhanced
- Biochemistry 1987, Green, C. L., Loechler, E. L., Fowler, K. W., & Essigmann,
- Pergamon Bk~organic&MedicinalChemistpy,Vol.4, No. 9, pp 1421-1427,1996 Copyright 1996ElsevierScienceLtd
- Craik, Charles Faculty Training History
- ANTAGONISTIC ANTI-UPAR ANTIBODIES SIGNIFICANTLY INHIBIT UPAR-MEDIATED CELLULAR SIGNALING AND MIGRATION
- A Novel Entamoeba histolytica Cysteine Proteinase, EhCP4, Is Key for Invasive Amebiasis and a Therapeutic Target*S
- Cell Host & Microbe Mycobacterium tuberculosis MycP1 Protease
- DOI: 10.1126/science.1169378 , 213 (2009);324Science
- Hemoglobin Cleavage Site-Specificity of the Plasmodium falciparum Cysteine Proteases Falcipain-2 and Falcipain-3
- Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug Design*S
- Engineering Ecotin for Identifying Proteins with a Trypsin Fold
- online | memorias.ioc.fiocruz.br Mem Inst Oswaldo Cruz, Rio de Janeiro, Vol. 104(Suppl. I): 263-269, 2009
- Biol. Chem., Vol. 389, pp. 623632, June 2008 Copyright by Walter de Gruyter Berlin New York. DOI 10.1515/BC.2008.075 Article in press -uncorrected proof
- The functional expression and characterisation of a cysteine peptidase from the invasive stage of the neuropathogenic schistosome Trichobilharzia regenti q
- Subscriber access provided by -Access paid by the | UCSF Library Nano Letters is published by the American Chemical Society. 1155 Sixteenth
- IrAE An asparaginyl endopeptidase (legumain) in the gut of the hard tick Ixodes ricinus q
- doi:10.1110/ps.062179006 2006 15: 1229-1238; originally published online May 2, 2006;Protein Sci.
- Granzyme B Proteolyzes Receptors Important to Proliferation and Survival, Tipping the Balance toward Apoptosis*S
- Biochem. J. (2005) 390, 125136 (Printed in Great Britain) doi:10.1042/BJ20041955 125 Hepatocyte growth factor is a preferred in vitro substrate for human
- treatment are self-regulatory, through the activation of lymphocytes, which inhibit the activity of
- Albumin Is a Substrate of Human Chymase PREDICTION BY COMBINATORIAL PEPTIDE SCREENING AND DEVELOPMENT OF A SELECTIVE INHIBITOR
- Cellular Localization of Membrane-type Serine Protease 1 and Identification of Protease-activated Receptor-2 and Single-chain
- Determining Protein-Protein Interactions by Oxidative Cross-Linking of a Glycine-Glycine-Histidine Fusion Protein
- Engineering Bidentate Macromolecular Inhibitors for Trypsin and Urokinase-type Plasminogen Activator
- Crystal Structure of an Ecotin-Collagenase Complex Suggests a Model for Recognition and Cleavage of the Collagen Triple Helix
- Biochem. J. (1996) 320, 681686 (Printed in Great Britain) 681 Bile pigments as HIV-1 protease inhibitors and their effects on HIV-1 viral
- 3426 J.Med. Chem. 1992,35,3426-3428 Specific Inhibition of HIV-1 Protease by
- I06 Biochemistry 1991, 30, 106-1 11 Wallace, C. J. A. (1987) J. Biol. Chem. 262, 16767-16770.
- 9264 Biochemistry 1989, 28, 9264-9270 Crystal Structures of Two Engineered Thiol Trypsins?
- Macromolecular Inhibitors of HIV-1 Protease CHARACTERIZATION OF DESIGNED HETERODIMERS*
- Delocalizing Trypsin Specificity with Metal Activation W. Scott Willett,, Linda S. Brinen,| Robert J. Fletterick,| and Charles S. Craik*,
- Computer-assisted Mutagenesis of Ecotin to Engineer Its Secondary Binding Site for Urokinase Inhibition*
- UNIVERSITY OF CALIFORNIA UNIVERSITY OF CALIFORNIA
- Methyl Groups as Probes for Proteins and Complexes in In-Cell NMR Experiments
- Active Plasma Kallikrein Localizes to Mast Cells and Regulates Epithelial Cell Apoptosis, Adipocyte Differentiation, and
- Communication between the active sites and dimer interface of a herpesvirus protease revealed by a
- SmCL3, a Gastrodermal Cysteine Protease of the Human Blood Fluke Schistosoma mansoni
- Pergamon Bioonganic & Medicinal Chemistry, Vol. 5, No. 7, pp 1311-1320, 1997 ~) 1997 Elsevier Science Ltd
- Proc. Natl. Acad. Sci. USA Vol. 93, pp. 1147711481, October 1996
- 9256 Biochemistry 1989, 28, 9256-9263 Introduction of a Cysteine Protease Active Site into Trypsin?
- Journal of Biomolecular NMR 30: 175179, 2004. 2004 Kluwer Academic Publishers. Printed in the Netherlands.
- 4148 Biochemistry 1989, 28, 4148-4155 Molecular Cloning of Dog Mast Cell Tryptase and a Related Protease: Structural
- Granzyme M Is a Regulatory Protease That Inactivates Proteinase Inhibitor 9, an Endogenous Inhibitor of Granzyme B*
- COMMUNICATION Auto-inactivation by Cleavage within the Dimer
- DOI: 10.1002/cbic.201000442 Mechanisms of Macromolecular Protease Inhibitors
- has yet to be ascertained. However, the significant correlation between MT-SP1 and uPAR transcript lev-
- Inhibition of a Viral Enzyme by a Small Molecule Dimer Disruptor Tina Shahian1, Gregory M. Lee2, Ana Lazic2, Leggy A. Arnold3, Priya Velusamy3, Christina
- Chemistry & Biology, Vol. 12, 567577, May, 2005, 2005 Elsevier Ltd All rights reserved. DOI 10.1016/j.chembiol.2005.03.006 Selective Chemical Functional Probes of Granzymes
- BIOINFORMATICS ORIGINAL PAPER Vol. 26 no. 14 2010, pages 17141722
- Biochemical Properties of a Novel Cysteine Protease of Plasmodium vivax, Vivapain-4
- This article was published in an Elsevier journal. The attached copy is furnished to the author for non-commercial research and
- Coordinate expression and functional profiling identify an extracellular proteolytic signaling pathway
- Continuous imaging of plasmon rulers in live cells reveals early-stage caspase-3 activation
- Potent and Selective Inhibition of Membrane-Type Serine Protease 1 by Human Single-Chain Antibodies
- Isotope-Coded and Affinity-Tagged Cross-Linking (ICATXL): An Efficient Strategy to Probe Protein Interaction Surfaces
- Biochemistry 1995, 34, 11521-1 1527 11521 Trypsin Specificity Increased through Substrate-Assisted Catalysis?
- Biochem. J. (2002) 368, 273281 (Printed in Great Britain) 273 Critical role of amino acid 23 in mediating activity and specificity of
- 8582 Biochemistry 1990, 29, 8582-8586 Regulation of Serine Protease Activity by an Engineered Metal Switch?
- 6194 J. Org. Chem. 1994,59, 6194-6199 Nonpeptide HIV Protease Inhibitors. Differential Introduction of
- Biochem. J. (2004) 379, 107118 (Printed in Great Britain) 107 The periplasmic serine protease inhibitor ecotin protects bacteria against
- Plasminogen activation independent of uPA and tPA maintains wound healing in gene-deficient
- Expression and characterization of constitutively active human caspase-14 q
- of October 25, 2010 This information is current as
- Biochem. J. (2011) 435, 116 (Printed in Great Britain) doi:10.1042/BJ20100965 1 REVIEW ARTICLE
- Characterization of Structural Determinants of Granzyme B Reveals Potent Mediators of Extended Substrate Specificity*
- Proc. Natl. Acad. Sci. USA Vol. 96, pp. 1105411061, September 1999
- Anisotropic Dynamics of the JE-2147-HIV Protease Complex: Drug Resistance and Thermodynamic Binding Mode Examined in a 1.09 Structure,
- 1 Enzyme Inhibition by Allosteric Capture of an 2 Inactive Conformation
- This Provisional PDF corresponds to the article as it appeared upon acceptance. Fully formatted PDF and full text (HTML) versions will be made available soon.
- -% , & , *% " . ) " * 0 , , . -, ,% 1# #23444 (% # &
- IrCL1 The haemoglobinolytic cathepsin L of the hard tick, Ixodes ricinus Zdenek Franta a,b
- 2 Inhibitors of SARS-CoV entry Identification using an internally-controlled 3 dual envelope pseudovirion assay
- LETTER doi:10.1038/nature10719 Global landscape of HIVhuman protein complexes
- A Reverse Binding Motif That Contributes to Specific Protease Inhibition by Antibodies
- Rapid identification of recombinant Fabs that bind to membrane proteins JungMin Kim a
- The Prostate Inhibition of Granzyme B by PI-9 Protects Prostate
- LETTER doi:10.1038/nature10693 Vif hijacks CBF-b to degrade APOBEC3G and
