- Introduction Part II Molecular Dynamics Simulations on Membrane Peptides or
- DPhil Thesis Chapter 8 Conclusions Chapter 8 Conclusions
- 760 Biochemical Society Transactions (2007) Volume 35, part 4 Neurotensin receptor type 1: Escherichia coli
- Transmembrane helices of membrane proteins may flex to satisfy hydrophobic mismatch
- 2. Bacteriorhodopsin and the Purple Membrane Fig 2.1. The helical disposition of bacteriorhodopsin showing the seven trans-membrane region (derived
- COMMUNICATION Advances towards resonance assignments for uniformly--13
- Structural insights into the binding of cardiac glycosides to the digitalis receptor revealed
- Interfacial Anchor Properties of Tryptophan Residues in Transmembrane Peptides Can Dominate over Hydrophobic Matching Effects in Peptide-Lipid Interactions
- Chapter 5 Determining the -Ionone ring conformation of
- Cholesterol Modulates the Organization of the gM4 Transmembrane Domain of the Muscle Nicotinic Acetylcholine Receptor
- A Model of Reversible Inhibitors in the Gastric H /K -ATPase Binding Site Determined by Rotational Echo Double Resonance
- I.2 New insights into the bonding arrangements of L-and D-glutamates from
- I.1 A Review of Oxygen-17 Solid State NMR of Organic Materials
- Constitutive Dimerization of the G-Protein Coupled Receptor, Neurotensin Receptor 1, Reconstituted into Phospholipid Bilayers
- Structure and dynamics of the gM4 transmembrane domain of the acetylcholine receptor in lipid bilayers: insights into receptor
- Abstract Despite their clinical importance, detailed analysis of ligand binding at G-protein coupled recep-
- Chapter 6 General discussion 6.1 The helix movement model of rhodopsin activation
- F} REDOR for distance measurements in biological solids using a double resonance spectrometer
- 8980 J. Org. Chem. 2009, 74, 89808987 Published on Web 11/02/2009 DOI: 10.1021/jo9014497 r 2009 American Chemical Society
- 6. Protein-Lipid Interactions in Purple Membrane and Reconstituted Rhodopsin Containing Membranes Studied by
- REDOR NMR on a Hydrophobic Peptide in Oriented Membranes David A. Middleton,1
- Structural Studies on the Hydration of L-Glutamic Acid in Solution Sylvia E. McLain,*,, Alan K. Soper, and Anthony Watts,
- Towards selective recoupling and mutual decoupling of dipolar-coupled spin pairs in double-quantum magic-angle
- DPhil Thesis Bibliography Bibliography
- Orientational Order of Australian Spider Silks as Determined by
- Biomembrane Structure Unit, Biochemistry
- DPhil Thesis Chapter 4 Rotational Resonance Experiments Chapter 4 Rotational Resonance
- proteinsSTRUCTURE O FUNCTION O BIOINFORMATICS Solid-state NMR and simulation studies of
- Protein Expression and Purification 64 (2009) 3238 1046-5928/$ -see front matter 2008 Elsevier Inc. All rights reserved.
- Structural and orientational constraints of bacteriorhodopsin in purple membranes determined by oriented-sample solid-state
- Lemaitre et al Supporting Information 1 Figure 1: Supporting information for Figure 3 in manuscript. (A) Backbone RMSD of bovine
- Ligand Docking in the Gastric H+ -ATPase: Homology Modeling of Reversible
- Unfolding and Extraction of a Transmembrane a-Helical Peptide: Dynamic Force Spectroscopy and Molecular Dynamics Simulations
- Two Types of Alzheimer's b-Amyloid (140) Peptide Membrane Interactions: Aggregation Preventing
- The FASEB Journal Research Communication Targeting extracellular pyrophosphates underpins the
- The Ring of the Rhodopsin Chromophore in a Hydrophobic Activation Switch Within the Binding
- Accelerated Publications Conformational Similarities in the -Ionone Ring Region of the Rhodopsin
- Structural and orientational information of the membrane embedded M13 coat protein by 13
- Rotational Mobility and Orientational Stability of a Transport Protein in Lipid Membranes
- Model generation of viral channel forming 2B protein bundles from polio and coxsackie viruses
- Enhancing resolution and sensitivity of 17 O solid-state NMR
- Molecular Dynamics Simulations of Retinal in Rhodopsin: From the Dark-Adapted State towards Lumirhodopsin
- Combined Quantitative and Mechanistic Study of DrugMembrane Interactions Using
- 2382 Biophysical Journal Volume 84 April 2003 23822392 Effects of the Eukaryotic Pore-Forming Cytolysin Equinatoxin II
- Dynamics and orientation of N (CD3)3-bromoacetylcholine bound to its
- Structural Analysis of the Protein/Lipid Complexes Associated with Pore Formation by the Bacterial Toxin Pneumolysin*
- Journal of Magnetic Resonance 149, 90102 (2001) doi:10.1006/jmre.2001.2290, available online at http://www.idealibrary.com on
- Structural insight into the interaction of amyloid- peptide with biological membranes by solid state NMR.
- DPhil Thesis Chapter 2 Solid-State NMR Chapter 2 Solid-State NM R
- I.3 Solid State 17 O NMR as a probe for
- II.2 Molecular Dynamic Simulations Of Retinal In Rhodopsin: From The Dark-
- A.1 Solid State 17 O NMR of Amino Acids
- The conformation of the -ionone ring region of the chromophore of rhodopsin,
- Chapter 7 Conclusions and future 7.1 General Conclusions
- DPhil Thesis Bibliography Bibliography
- DPhil Thesis Chapter 1 Introduction Chapter 1 Introduction
- DPhil Thesis Chapter 3 Characterisation of Inhibitors Chapter 3 Characterisation of Inhibitors
- DPhil Thesis Chapter 6 Modelling of the Bound Inhibitor Chapter 6 Modelling of R414983 Bound to
- DPhil Thesis Bibliography Bibliography
- Appendix 1. Amino acids and their number in bacteriorhodopsin
- Probing Inhibitor Binding Sites in
- C h a p t e r 1 INTRODUCTION
- C h a p t e r 3 H SOLID STATE NMR OF INHIBITORS OF THE
- INTRODUCTION PART I 11 Introduction Part I Solid State NMR
- II.1 Conformational Studies of Retinal in Vincent Lematre,1,2
- Chapter 2 Preparation of 13 rhodopsin samples in ROS
- Chapter 4 Trapping the meta-I photointermediate in
- Probing the Structure of Acetylcholinesterase Inhibitors in their Binding Site using
- DPhil Thesis Chapter 5 REDOR Experiments Chapter 5 Rotational-Echo Double-
- 5. Multiple Angular Constraints from Specifically Labelled Bacteriorhodopsin Identified by 15
- 7. Future Perspective 7.1 Benefits of solid-state NMR
- Aharoni, A., Weiner, L., Ottolenghi, M. & Sheves, M. (2000) Bacteriorhodopsin Experiences Light Induced Conformational Alterations in Nonisomerizable C13=C14
- C h a p t e r 5 A MODEL OF TMPFPIP AT ITS BINDING SITE IN
- C h a p t e r 6 DYNAMIC AND STRUCTURAL INFORMATION
- Selective NMR observation of inhibitor and sugar binding to the galactose-H
- C h a p t e r 7 CONCLUSIONS
- Solid-State 17 O NMR as a Probe for Structural Studies of Proteins in
- Identifying Anisotropic Constraints in Multiply Labeled Bacteriorhodopsin by 15
- C h a p t e r 2 SYNTHESIS AND FUNCTIONAL
- II.3 Membrane Peptide Interactions Studied by Molecular Dynamic Simulations of Atomic
- Chapter 3 Determining the -ionone ring conformation of retinal
- C h a p t e r 4 F REDOR NMR STUDIES OF THE
- A solid-state NMR study of the phospholamban transmembrane domain: local structure and interactions with Ca2
- Characterization and assignment of uniformly labeled NT(8-13) at the agonist binding site of the G-protein coupled neurotensin
- II.4 Interaction of amiloride and its derivatives with Vpu from HIV-1: a MD simulation study
- 3. The Reorientation of the Retinal Chromophore in Bacteriorhodopsin Revealed by Deuterium MAOSS NMR
- Differential Stiffness and Lipid Mobility in the Leaflets of Purple Membranes
- P. T. F. Williamson B. H. Meier A. Watts Structural and functional studies of the nicotinic acetylcholine
- Non-covalent interactions in biomolecules studied by 17
- A BIOPHYSICAL STUDY OF THE G PROTEIN COUPLED RECEPTOR
- Interaction of the Lantibiotic Nisin with Mixed Lipid Bilayers: H NMR Study
- Structure and dynamics of lipid-associated states of apocytochrome c Elzbieta A. Bryson1
- P-CP^MAS NMR studies on TPP bound to the ion-coupled multidrug
- High Resolution Structural Studies of Membrane Proteins Using
- Chapter 1 Introduction 1.1 Biological membranes
- Probing Structures of Membrane Proteins andTheir Inhibitors
- Journal of Biomolecular NMR, 26: 283295, 2003. KLUWER/ESCOM
- Nature 405, 810 -813 (2000); doi:10.1038/35015604 Observations of light-induced structural
- DPhil Thesis Chapter 5 Modelling Study of the Gastric H+ Chapter 5 M odellingStudyofthe Gastric
- Peptide Clusters DOI: 10.1002/anie.200802679
- Helix Conformations in 7TM Membrane Proteins Determined Using Oriented-Sample Solid-State NMR with Multiple Residue-Specific
- Author's personal copy Heterologous high yield expression and purification of neurotensin and its
- Solid-State NMR Studies of Bacteriorhodopsin and the Purple Membrane
- NMR crystallography: The effect of deuteration on high resolution 13 state NMR spectra of a 7-TM protein
- DPhil Thesis Chapter 3 Materials and Methods Chapter 3 M aterialsandM ethods
- Probing the environment of neurotensin whilst bound to the neurotensin receptor by solid state NMR
- DPhil Thesis Chapter 7 Drug-Protein Interaction with Vpu from HIV-1 Chapter 7 Drug-ProteinInteractionwith Vpu
- The conformation of acetylcholine at its target site in the membrane-embedded nicotinic
- Expression and Purification of Recombinant Neurotensin in Escherichia coli1
- Structure and Hydration of L-Proline in Aqueous Solutions Sylvia E. McLain,*,, Alan K. Soper, Ann E. Terry, and Anthony Watts
- Structural and dynamic studies of the g-M4 trans-membrane domain of the nicotinic acetylcholine receptor
- Functionally Relevant Coupled Dynamic Profile of Bacteriorhodopsin and Lipids in Purple Membranes
- 4. Helix-Retinal Relationships in Bacteriorhodopsin using Homonuclear 13
- Solid State Nuclear Magnetic Resonance 26 (2004) 215235 A review of oxygen-17 solid-state NMR of organic
- DPhil Thesis Chapter 7 Conclusions Chapter 7 Conclusions
- Membrane Thickening by the Antimicrobial Peptide PGLa Georg Pabst,* Stephan L. Grage,y
- SHORT COMMUNICATION Drugprotein interaction with Vpu from HIV-1: proposing
- DPhil Thesis Chapter 6 Probing R414983 Bound to Acetylcholinesterase Chapter 6 ProbingR414983Boundto
- New Limits for Solid-State 17 O NMR Spectroscopy: Complete Resolution of
- DPhil Thesis Chapter 1 Introduction Chapter 1 Introduction
- DPhil Thesis Chapter 2 Synthesis Chapter 2 Synthesis of Labelled Inhibitors
- Relative Orientation between the -Ionone Ring and the Polyene Chain for the Chromophore of Rhodopsin in Native Membranes
- Electrostatic peptidelipid interactions of amyloid-b peptide and pentalysine with membrane surfaces monitored by 31P MAS NMR
- 1. Introduction to Membrane Protein Structure and Solid-Fig 1.1. Diagram describing the organisation of a typical cell membrane and its relationship to the cell
- -Sheet Structured -Amyloid(1-40) Perturbs Phosphatidylcholine Model Membranes
- Solid-State 17O NMR of Amino Acids K. J. Pike, V. Lemaitre,, A. Kukol,| T. Anupo~ld, A. Samoson, A. P. Howes, A. Watts,
- New insights into the bonding arrangements of LL-and DD-glutamates from solid state 17
