Bushman, Frederic - Department of Microbiology, University of Pennsylvania

• Cell, Vol. 115, 135138, October 17, 2003, Copyright 2003 by Cell Press MinireviewTargeting Survival
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• High-Definition Mapping of Retroviral Integration Sites Defines the Fate of Allogeneic T Cells After Donor
• Modeling HIV-1 Integrase Complexes Based on Their
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• Gene transfer in humans using a conditionally replicating lentiviral vector
• Retroviral DNA integration: HIV and the role of LEDGF/p75
• PyNAST: A flexible tool for aligning sequences to a template alignment.
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• The Mobility of an HIV-1 Integrase Active Site Loop Is Correlated with Catalytic Jason Greenwald,,| Vincent Le,,| Scott L. Butler, Frederic D. Bushman, and Senyon Choe*,
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• HTLV-1 Integration into Transcriptionally Active Genomic Regions Is Associated with Proviral Expression and with
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• Developing a Dynamic Pharmacophore Model for HIV-1 Integrase Heather A. Carlson,*, Kevin M. Masukawa, Kathleen Rubins, Fredric D. Bushman, William L. Jorgensen,
• Selection of Target Sites for Mobile DNA Integration in the Human Genome
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• Global Analysis of Host-Pathogen Interactions that Regulate
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• Construction and analysis of cells lacking the HMGA gene family
• Integration target site selection by a resurrected human endogenous retrovirus
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• DNA Branch Nuclease Activity of Vaccinia A22 Resolvase*S Received for publication,June 28, 2007, and in revised form, September 7, 2007 Published, JBC Papers in Press,September 21, 2007, DOI 10.1074/jbc.M705322200
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• 578 NATURE BIOTECHNOLOGY VOL 17 JUNE 1999 http://biotech.nature.com Chemotherapy for HIV currently employs inhibitors of the viral
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• A method to sequence and quantify DNA integration for monitoring outcome in gene therapy
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• METHODOLOGY ARTICLE Open Access Sampling and pyrosequencing methods for
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• DNA Binding and Cleavage by the Fowlpox Virus Resolvase*S Received for publication,October 14, 2008, and in revised form, November 10, 2008 Published, JBC Papers in Press,November 12, 2008, DOI 10.1074/jbc.M807864200
• Variola virus topoisomerase: DNA cleavage specificity and distribution of sites in Poxvirus genomes
• Role of metal ions in catalysis by HIV integrase analyzed using a quantitative PCR
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• Retroviral DNA Integration: Viral and Cellular Determinants of Target-Site
• Single-particle Image Reconstruction of a Tetramer of HIV Integrase Bound to DNA
• Published online 18 September 2007 Nucleic Acids Research, 2007, Vol. 35, No. 18 e120 doi:10.1093/nar/gkm541
• DNA cleavage by the A22R resolvase of vaccinia virus Matthew J. Culyba, Jessamina E. Harrison, Young Hwang, Frederic D. Bushman
• Journal of Virological Methods 135 (2006) 118123 A statistical method for comparing viral growth curves
• Molecular Cell 23, 343354, August 4, 2006 2006 Elsevier Inc. DOI 10.1016/j.molcel.2006.06.015 Structural Basis for Specificity
• HIV Integration Site Selection: Targeting in Macrophages and the Effects of Different
• The DNA repair genes XPB and XPD defend cells from retroviral infection
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• Retroviral DNA Integration: ASLV, HIV, and MLV Show
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• research papers 536 Molteni et al. Small-molecule binding site in HIV integrase Acta Cryst. (2001). D57, 536544
• A New Class of HIV-1 Integrase Inhibitors: The 3,3,3,3-Tetramethyl-1,1-spirobi(indan)-5,5,6,6-tetrol Family
• Crystal Structure of an Active Two-domain Derivative of Rous Sarcoma Virus Integrase
• Lamellarin r 20-Sulfate, an Inhibitor of HIV-1 Integrase Active against HIV-1 Virus in Cell Culture
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• Target DNA capture by HIV-1 integration complexes Michael D. Miller*, Yeou-Cherng Bort and Frederic Bushman*
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• The EMBO Journal vol.12 no.8 pp.3269-3275, 1993 Identification of discrete functional domains of HIV-1
• Host Cell Factors in HIV Replication: Meta-Analysis of Genome-Wide Studies
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• MICHAELD.MILLERAND FREDERIC D. BUSHMAN HIV INTEGRATION~~~~~~~~~~ Inil for integration?
• The fluidity of an organism's DNA is under appreciated. Surprisingly often, DNA is transferred from one organism to another, to become stably incorporated and permanently change the recipient's genetic composition.
• once was. Why do cells devote resources to altering the biochemistry. Many of these chapters are written from meaning of the nucleotide sequences originally speci-a broad historical perspective that is not accessible
• 02/10/2006 11:43 AMCalculating Viral Growth Curves Page 1 of 1file:///Users/abritt/Desktop/wangSite/wangTutorial/index.html
• Role of PSIP1/LEDGF/p75 in Lentiviral Infectivity and Integration Targeting
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• Paired DNA Three-Way Junctions as Scaffolds for Assembling Integrase Complexes Erik P. Johnson and Frederic D. Bushman1
• Methods for integration site distribution analyses in animal cell genomes Angela Ciuffi b
• Dolastatin 3 and Two Novel Cyclic Peptides from a Palauan Collection of Lyngbya majuscula
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• Roles of host cell factors in circularization of retroviral DNA Jennifer M. Kilzer,a
• HIV Integration Targeting: A Pathway Involving Transportin-3 and the Nuclear Pore Protein RanBP2
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• Molecular Cell, Vol. 10, 961971, November, 2002, Copyright 2002 by Cell Press The near-consensus UnaL2 element was marked toConstructing the Vertebrate
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• Cyclodidemniserinol Trisulfate, a Sulfated Serinolipid from the Palauan
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• Integration Site Selection by HIV-Based Vectors in Dividing and Growth-Arrested IMR-90 Lung Fibroblasts
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• Global Analysis of Cellular Transcription Following Infection with an HIV-Based Vector
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• The Macaque Gut Microbiome in Health, Lentiviral Infection,
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• Nucleic Acids Research, Vol. 19, No. 10 2729 A rapid in vitro assay for HIV DNA integration
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