- Regulation of Cell-Fate Determination in Dictyostelium
- A novel, putative MEK kinase controls developmental timing and spatial
- INTRODUCTION In Dictyostelium, the multicellular organism is formed by the
- Protein Tyrosine Phosphatase PTP1 Negatively Regulates Dictyostelium STATa and Is Required
- Regulated protein degradation controls PKA function and cell-type differentiation
- lagC-Null and gbf-Null Cells Define Key Steps in the Morphogenesis of Dictyostelium Mounds
- Molecular Biology of the Cell Vol. 15, 54565469, December 2004
- The Rockefeller University Press, 0021-9525/97/03/1271/16 $2.00 The Journal of Cell Biology, Volume 136, Number 6, March 24, 1997 12711286 1271
- Feedback signaling controls leading-edge formation during chemotaxis
- A PTEN-related 5-Phosphatidylinositol Phosphatase Localized in the Golgi*
- The ability to chemotax, that is, to sense and move in the direc-tion of chemical signals, is a feature of a wide variety of eukary-
- Role of Phosphatidylinositol 3-Kinases in Chemotaxis in Dictyostelium*
- The novel ankyrin-repeat containing kinase ARCK-1 acts as a suppressor of the Spalten signaling pathway
- INTRODUCTION Pattern develops through an interaction of localized transcrip-
- MOLECULAR AND CELLULAR BIOLOGY, May 2007, p. 38173827 Vol. 27, No. 10 0270-7306/07/$08.00 0 doi:10.1128/MCB.02194-06
- Aubry, L., S. Lee, K. Ravanel and R.A. Firtel (2003). The novel ankyrin-repeat containing kinase ARCK-1 acts as a suppressor of
- Requirement of a Vasodilator-stimulated Phosphoprotein Family Member for Cell Adhesion, the Formation of Filopodia, and
- Decades of study of the processes that control multicellu-lar development have yielded a wealth of information.
- Sasaki, A.T. and R.A. Firtel (2006). Regulation of chemotaxis by the orchestrated activation of Ras, PI3K, and TOR. Eur. J. Cell Biol.
- Developmental Cell, Vol. 3, 120, June, 2002, Copyright 2002 by Cell Press Regulated SUMOylation and Ubiquitination of DdMEK1
- THEJOURNALOFCELLBIOLOGY JCB: REPORT
- Molecular Biology of the Cell Vol. 11, 12751291, April 2000
- INTRODUCTION Dictyostelium discoideum cells form a multicellular organism
- Molecular Biology of the Cell Vol. 16, 21912206, May 2005
- Takeda, K., A.T. Sasaki , H. Ha, H. Seung and R.A. Firtel (2007). Role of phosphatidylinositol 3-kinases in chemotaxis in Dictyostelium.
- Functional and Regulatory Analysis of the Dictyostelium G-Box Binding Factor
- Uncorrected Proof Copy Uncorrected Proof Copy
- INTRODUCTION Nutrient-deprived Dictyostelium cells aggregate to form a mul-
- Mendoza, M.C., F. Du, N. Iranfar, N. Tang, H. Ma, W.F. Loomis and R.A. Firtel (2005). Loss of SMEK, a novel, conserved protein,
- Molecular Biology of the Cell Vol. 10, 28292845, September 1999
- Mendoza, M.C. and R.A. Firtel (2006). Assaying chemotaixs of Dictyostelium cells. In: Methods in Molecular Biology, Vol. 346
- Molecular Biology of the Cell Vol. 8, 19892002, October 1997
- Molecular Biology of the Cell Vol. 16, 45724583, October 2005
- Dictyostelium 6 A Model Experimental System for Elucidating the Pathways
- Dictyostelium has played an important role in unraveling the pathways that control cell movement and chemotaxis. Recent
- Rac regulation of chemotaxis and morphogenesis in Dictyostelium
- Annu. Rev. Cell Dev. Biol. 1999. 15:469517 Copyright c 1999 by Annual Reviews. All rights reserved
- The Rockefeller University Press, 0021-9525/2001/05/795/15 $5.00 The Journal of Cell Biology, Volume 153, Number 4, May 14, 2001 795809
- THEJOURNALOFCELLBIOLOGY The Rockefeller University Press $8.00
- Sasaki, A.T., C. Chun, K. Takeda and R.A. Firtel (2004). Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and
- Lee, S., F. Rivero, K.C. Park, E. Huang, S. Funamoto and R.A. Firtel (2004). Dictyostelium PAKc is required for proper chemotaxis. Mol.
- Breaking symmetries: regulation of Dictyostelium development through chemoattractant and morphogen signal-response
- MOLECULAR AND CELLULAR BIOLOGY, Sept. 2005, p. 78397853 Vol. 25, No. 17 0270-7306/05/$08.00 0 doi:10.1128/MCB.25.17.78397853.2005
- Charest, P.G. and R.A. Firtel (2006). Feedback signaling controls leading-edge formation during chemotaxis. Curr. Opin. Genet. Devel.
- European Journal of Cell Biology 85 (2006) 873895 Regulation of chemotaxis by the orchestrated activation of Ras,
- Biochem. J. (2007) 401, 377390 (Printed in Great Britain) doi:10.1042/BJ20061432 377 REVIEW ARTICLE
- THEJOURNALOFCELLBIOLOGY JCB: ARTICLE
- Jeon, T.J., D. Lee, S. Merlot, N. Nguyen, G. Weeks and R.A. Firtel (2007). Rap1 controls cell adhesion and cell motility through the
- Mendoza, M.C., E.O. Booth, G. Shaulsky and R.A. Firtel (2007). MEK1 and protein phosphatase 4 coordinate Dictyostelium
- Spatio-temporal analysis of eukaryotic cell motility by improved force cytometry
- Del Alamo, J.C., R. Meili, B. Alonso-Latorre, J. Rodriguez-Rodriguez, A. Aliseda, R.A. Firtel and J.C. Lasheras (2007). Spatio-temporal
- DEVELOPMENTAL BIOLOGY 181, 7990 (1997) ARTICLE NO. DB968447
- Spalten, a protein containing G -protein-like and PP2C domains,
- INTRODUCTION Understanding the interplay of cell-cell interactions and signal
- The EMBO Journal Vol.17 No.14 pp.40184028, 1998 Developmentally and spatially regulated activation
- seminars in CELL & DEVELOPMENTAL BIOLOGY, Vol 10, 1999: pp. 597 607 Article No. scdb.1999.0343, available online at http:rrwww.idealibrary.com on
- Role of Rac in controlling the actin cytoskeleton and chemotaxis in motile cells
- The molecular genetics of chemotaxis: sensing and
- An F-Box/WD40 Repeat-Containing Protein Important for Dictyostelium Cell-Type
- 708 Research Paper A novel Akt/PKB-related kinase is essential for morphogenesis
- An SH2-domain-containing kinase negatively regulates the
- Han, Y-H., C.Y. Chung, S. Stephens, D. Wessels, M.A. Titus, D.R. Soll and R.A. Firtel (2002). Requirement of a vasodilator-stimulated
- Meili, R and R.A. Firtel (2002). Leading the way. Nature Cell Biol. The ability to chemotax, that is, to sense and move in the direction
- Molecular Biology of the Cell Vol. 14, 17271743, April 2003
- Sun, B. and R.A. Firtel (2003). A regulator of G protein signaling-containing kinase is important for chemotaxis and multicellular
- Merlot, S., R. Meili, D. Pagliarini, T. Maehama, J.E. Dixon and R.A. Firtel (2003). A PTEN-related 5'-phosphatidylinositol phosphatase
- 20. E. Smirnova, D. Shurland, S. Ryazantsev, A. Van Der Bliek, J. Cell Biol. 143, 351 (1998).
- 334 NATURE CELL BIOLOGY VOLUME 7 | NUMBER 4 |APRIL 2005 NEWS AND VIEWS
- INTRODUCTION Ras proteins are members of the small GTP-binding/GTPase
- Park, K.C., F. Rivero, R. Meili, S. Lee, F. Apone and R.A. Firtel (2004). Rac regulation of chemotaxis and morphogenesis in Dictyostelium.
- Sasaki, A., C. Janetopoulos, S. Lee, P.G. Charest, K. Takeda, L.W. Sundheimer, R. Meili, P.N. Devreotes and R.A. Firtel (2007). G
- The EMBO Journal Vol.16 No.14 pp.43174332, 1997 The Dictyostelium MAP kinase kinase DdMEK1
- The Rockefeller University Press, 0021-9525/99/11/559/17 $5.00 The Journal of Cell Biology, Volume 147, Number 3, November 1, 1999 559575
- Activation of the Mitogen-activated Protein Kinase ERK2 by the Chemoattractant Folic Acid in Dictyostelium*
- Myers, S.A., J.W. Han, Y. Lee, R.A. Firtel and C.Y. Chung (2005). A Dictyostelium homologue of WASP is required for polarized F-actin
- Regulation of Dictyostelium Protein-tyrosine Phosphatase-3 (PTP3) through Osmotic Shock and Stress Stimulation and Identification of
- The EMBO Journal Vol.18 No.8 pp.20922105, 1999 Chemoattractant-mediated transient activation and
- Lee, S., F.I. Comer, A. Sasaki, I.X. McLeod, Y. Duong, K. Okamura, J.R. Yates III, C.A. Parent and R.A. Firtel (2005). TOR Complex 2
