- hyperactivated motility All four CatSper ion channel proteins are required for male fertility and sperm cell
- J. Biol. Chem. 273, 2372223728 (1998). 7. Graeler, M. & Goetzl, E. J. Activation-regulated expression and chemotactic function of sphingosine
- The G Protein Subunit Transduces the Muscarinic Receptor Signal for Ca2
- Structural characterization of the mouse Girk genes Kevin Wickmana,*, William T. Pub
- Neuron 52, 485496, November 9, 2006 2006 Elsevier Inc. DOI 10.1016/j.neuron.2006.09.033 The TRPM7 Ion Channel Functions in Cholinergic
- Formation of Novel TRPC Channels by Complex Subunit Interactions in Embryonic Brain*S
- References and Notes 1. C. R. Jones et al., Nature Med. 5, 1062 (1999).
- Neurobiology of Disease Ketogenic Diet Metabolites Reduce Firing in Central Neurons
- The TRP channels are in the front lines of sensory systems, responding to temperature, touch, pain, osmolarity, pheromones, taste, and potentially hearing
- Development/Plasticity/Repair Phosphatidylinositol 3-Kinase Activates ERK in Primary
- Functional Expression and Characterization of G-protein-gated Inwardly Rectifying K+ Channels Containing GIRK3
- CatSper1 required for evoked Ca2 entry and control
- International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels
- Proc. Nati. Acad. Sci. USA Vol. 82, pp. 2168-2172, April 1985
- Received 9 Sep 2010 | Accepted 1 Dec 2010 | Published 11 Jan 2011 DOI: 10.1038/ncomms1153 Calcium signalling is critical for successful fertilization. In spermatozoa, capacitation,
- A RT I C L E The Rockefeller University Press $30.00
- A Prokaryotic Voltage-Gated Sodium Channel
- A voltage-gated ion channel expressed specifically in spermatozoa
- Proc. Nati. Acad. Sci. USA Vol. 81, pp. 3083-3087, May 1984
- Activating mutation in a mucolipin transient receptor potential channel leads to melanocyte loss in
- A R T I C L E S NATURE CELL BIOLOGY VOLUME 6 | NUMBER 8 | AUGUST 2004 709
- David Clapham last updated February 2, 2007 The TRPV Vanilloid Receptor Subfamily
- TRP ion channels in the nervous system Magdalene M Moran, Haoxing Xu and David E Clapham
- MOLECULAR AND CELLULAR BIOLOGY, Apr. 2005, p. 26322643 Vol. 25, No. 7 0270-7306/05/$08.00 0 doi:10.1128/MCB.25.7.26322643.2005
- Developmental Cell, Vol. 4, 561574, April, 2003, Copyright 2003 by Cell Press Mechanism of Persistent Protein Kinase D1
- David Clapham last updated February 2, 2007 The TRPM Melastatin Subfamily
- International Union of Pharmacology. XLI. Compendium of Voltage-Gated Ion Channels
- Cell, Vol. 76, 439-446, February 11, 1994, Copyright 0 1994 by Cell Press Molecular Characterization of a Swelling-Induced
- Citral Sensing by TRANSient Receptor Potential Channels in Dorsal Root Ganglion Neurons
- Polycom instruction Sheet Setting up and powering on
- INVITED REVIEW Bimal N. Desai David E. Clapham
- Number and Stoichiometry of Subunits in the Native Atrial G-protein-gated K Channel, IKACh*
- David Clapham last updated April 30, 2009 The TRPC Subfamily
- David Clapham last updated February 2, 2007 Distant TRPs (A, P, ML)
- TRP Channel Regulates EGFR Signaling in Hair Morphogenesis
- Hv1 proton channels are required for high-level NADPH oxidase-dependent superoxide production
- Essential Role for TRPC5 in Amygdala Function
- I O N C H A N N E L S TRPM1 Forms Ion Channels Associated with
- Mammalian MagT1 and TUSC3 are required for cellular magnesium uptake and vertebrate
- Evolutionary Genomics Reveals Lineage-Specific Gene Loss and Rapid Evolution of a Sperm-Specific Ion
- KSper, a pH-sensitive K current that controls sperm membrane potential
- CATSPER: A NOVEL TRANSMEMBRANE PROTEIN IN THE CATSPER CHANNEL COMPLEX*
- Leading Edge Cell 131, December 14, 2007 2007 Elsevier Inc. 1047
- TRP Activators Inhibitors Putative Interacting Proteins Proposed Functions Activation potentiated by PLC pathways Gd, La TRPC4, TRPC5, calmodulin, TRPC3,
- 2006 Nature Publishing Group Whole-cell patch-clamp measurements of
- International Union of Pharmacology. XLIX. Nomenclature and Structure-Function Relationships of
- Annu. Rev. Physiol. 2006. 68:61947 doi: 10.1146/annurev.physiol.68.040204.100431
- BISANDROGRAPHOLIDE FROM ANDROGRAPHIS PANICULATA ACTIVATES TRPV4 CHANNELS*
- International Union of Pharmacology. L. Nomenclature and Structure-Function Relationships of CatSper and
- International Union of Pharmacology. LIV. Nomenclature and Molecular Relationships of
- A Superfamily of Voltage-gated Sodium Channels in Bacteria*S Received for publication, December 1, 2003, and in revised form, December 9, 2003
- A Spontaneous, Recurrent Mutation in Divalent Metal Transporter-1
- The voltage-gated Na channel NaVBP has a role in motility, chemotaxis, and pH homeostasis
- Neuron, Vol. 43, 563574, August 19, 2004, Copyright 2004 by Cell Press SynGAP-MUPP1-CaMKII Synaptic Complexes Regulate
- Biophysical Journal Volume 84 February 2003 13171327 1317 Real-Time Imaging of Nuclear Permeation by EGFP in Single
- TRP channels as cellular sensors David E. Clapham
- A Superfamily of Voltage-Gated Sodium Channels in Bacteria Ryuta Koishi*, Haoxing Xu*, Dejian Ren$, Betsy Navarro,
- International Union of Pharmacology. XLIII. Compendium of Voltage-Gated Ion Channels
- 22 MARCH 2002 VOL 295 SCIENCE www.sciencemag.org2228 ature changes with 20th century observa-
- NATURE CELL BIOLOGY ADVANCE ONLINE PUBLICATION http://cellbio.nature.com 1 The TRPM7 channel is inactivated by
- 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 Lane 1= adrenal gland, 2=brain, 3=heart,
- J. Gen. Physiol. The Rockefeller University Press 0022-1295 http://www.jgp.org/cgi/doi/10.1085/jgp.20028618
- IUPHAR Compendium, TRP Channels July 10, 2002 1 The TRP Ion Channel Family
- Neuron, Vol. 29, 645655, March, 2001, Copyright 2001 by Cell Press TRPC1 and TRPC5 Form a Novel
- The Stoichiometry of G Binding to G-protein-regulated Inwardly Rectifying K Channels (GIRKs)*
- Fundamental Ca2 Signaling Mechanisms in Mouse Dendritic
- Evaluation of the Role of IKACh in Atrial Fibrillation Using a Mouse Knockout Model
- 2001 Macmillan Magazines Ltd The last bastion of ion channels is the transient receptor
- Distinct Ion Channel Classes Are Expressed on the Outer Nuclear Envelope of T-and B-Lymphocyte Cell Lines
- ICln Is Essential for Cellular and Early Embryonic Viability*
- Neuron, Vol. 23, 149157, May, 1999, Copyright 1999 by Cell Press Molecular Determinants for Subcellular
- G Binding Increases the Open Time of IKACh: Kinetic Evidence for Multiple G Binding Sites
- pICln Binds to a Mammalian Homolog of a Yeast Protein
- 114 nature neuroscience volume 1 no 2 june 1998 A longstanding hypothesis about information processing in the
- Neuron, Vol. 20, 103114, January, 1998, Copyright 1998 by Cell Press Abnormal Heart Rate Regulation
- Identification of Native Atrial G-protein-regulated Inwardly Rectifying K (GIRK4) Channel Homomultimers*
- Neuron, Vol. 20, 9951005, May, 1998, Copyright 1998 by Cell Press A Novel Inward Rectifier K Channel
- MECHANISMS OF DISEASE Volume 336 Number 22 1575
- Neuron, Vol. 16, 423429, February, 1996, Copyright 1996 by Cell Press Cloning of a Xenopus laevis Inwardly
- G Binds Directly to the G Protein-gated K
- Neuron, Vol. 19, 175184, July, 1997, Copyright 1997 by Cell Press Gated Access to the Pore
- Quarterly Reviews of Biophysics 31, 3 (1998), pp. 239295. Printed in the United Kingdom # 1998 Cambridge University Press
- Neuron, Vol. 41, 737744, March 4, 2004, Copyright 2004 by Cell Press Inactivation in HCN Channels Results
- Cellular/Molecular Camphor Activates and Strongly Desensitizes the Transient
- Conformational Changes of the in Situ Nuclear Pore Complex Hongwei Wang and David E. Clapham
- 2010NatureAmerica,Inc.Allrightsreserved. nature structural & molecular biology advance online publication
- change in intensity from this value. Care was taken to omit all changes that were due to focal shifts or sample movement in any dimension. The spatial extent (half-maximal
- ISSN: 1524-4571 Copyright 2006 American Heart Association. All rights reserved. Print ISSN: 0009-7330. Online
- Neuron,Vol. 14, 163-167,January,1995,Copyright 1995by Cell Press Calcium Release from the Nucleus
- Neuron, Vol. 29, 16, January, 2001, Copyright 2001 by Cell Press result of defective endosomal acidification (Piwon et al.,How to Lose Your Hippocampus
- 2006 Nature Publishing Group A voltage-gated proton-selective channel lacking
- 845 J. Gen. Physiol. The Rockefeller University Press 0022-1295/2002/12/845/9 $5.00 Volume 120 December 2002 845853
- NATURE |VOL 413 |11 OCTOBER 2001 |www.nature.com 603 A sperm ion channel required for sperm
- TheJournalofGeneralPhysiology J. Gen. Physiol. The Rockefeller University Press $8.00
- news and views nature structural biology volume 6 number 9 september 1999 807
- DOI: 10.1126/science.1163493 , 756 (2008);322Science
- PII: S0028-3908(96)00 [32-3 N(,ur(>plza)tttacology, Vol. 35, No, 7, pp. 831839, 1996
- Brain Localization and Behavioral Impact of the G-Protein-Gated K Channel Subunit GIRK4
- A Switch Mechanism for G Activation of IKACh* Received for publication, June 8, 2000, and in revised form, July 11, 2000
- Cell, Vol. 115, 641646, December 12, 2003, Copyright 2003 by Cell Press EssaySymmetry, Selectivity,
- Neuron, Vol. 40, 775784, November 13, 2003, Copyright 2003 by Cell Press The NMDA Receptor Is Coupled
- letters to nature NATURE |VOL 410 |5 APRIL 2001 |www.nature.com 705
- TRPM7 facilitates cholinergic vesicle fusion with the plasma membrane
- Cell, Vot.80, 259-268, January27, 1995,Copyright 1995by Cell Press Calcium Signaling Review
- This article was originally published in the Encyclopedia of Neuroscience published by Elsevier, and the attached copy is provided by Elsevier for the
- Functional and Biochemical Evidence for G-protein-gated Inwardly Rectifying K (GIRK) Channels Composed of GIRK2 and GIRK3*
- GIRK4 Confers Appropriate Processing and Cell Surface Localization to G-protein-gated Potassium Channels*
- 23. Schmidt, J. V., Matteson, P. G., Jones, B. K., Guan, X. J. & Tilghman, S. M. The Dlk1 and Gtl2 genes are linked and reciprocally imprinted. Genes Dev. 14, 19972002 (2000).
- 239 J. Gen. Physiol. The Rockefeller University Press 0022-1295/99/02/239/10 $2.00 Volume 113 February 1999 239248
- POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters
- Transient receptor potential cation channel, subfamily C, member 5 (TRPC5) is a cold-transducer in the
- PH74CH10-Clapham ARI 6 October 2011 14:18 The Control of Male Fertility
- ATP-activated P2X2 current in mouse spermatozoa Betsy Navarroa,1
- ARTICLE doi:10.1038/nature10567 Melanopsin signalling in mammalian iris
- Ancestral Ca21 Signaling Machinery in Early Animal and
- International Union of Basic and Clinical Pharmacology. LXXVI. Current Progress in the
- A thermodynamic framework for understanding temperature sensing by transient receptor
- POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters
- The channel kinase, TRPM7, is required for early embryonic development
