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Efficient Calculation of Interval Scores for DNA Copy Number Data Analysis
 

Summary: Efficient Calculation of Interval Scores for DNA Copy
Number Data Analysis
Doron Lipson1
, Yonatan Aumann2
, Amir Ben-Dor3
, Nathan Linial4
, and Zohar Yakhini1,3
1
Computer Science Dept., Technion, Haifa
2
Computer Science Dept., Bar-Ilan University, Ramat Gan
3
Agilent Laboratories
4
Computer Science Dept., Hebrew University of Jerusalem
Abstract
Background. DNA amplifications and deletions characterize cancer genome and are of-
ten related to disease evolution. Microarray based techniques for measuring these DNA
copy-number changes use fluorescence ratios at arrayed DNA elements (BACs, cDNA or
oligonucleotides) to provide signals at high resolution, in terms of genomic locations. These

  

Source: Aumann, Yonatan - Computer Science Department, Bar Ilan University

 

Collections: Computer Technologies and Information Sciences