Summary: 1
CLASS 3.4: 03/27/07
RETROVIRUSES AND RETROPOSONS
A. Retroviruses:
1. Life cycle
- Genomes consist
- Replicates through
- Has obligatory stage
- Integration occurs via
a. Implications of provirus integration
i. Integrated viral genome
ii. Nearby cellular sequences
iii. Nearby cellular sequences can
- Enzyme responsible
- Integrase enzyme
- Provirus genes and
- Typically,
2
2. Viral genes
- Typical retroviral genome contains