Summary: CHM 2220 Organic Chemistry 2220 Winter Term 2008
Problem Set #3 of 5 20 PTS Instructor: Prof. Andreana
Room #: DRY 0146
Teaching Assistant's Name:
1) Show how you might synthesize the following compounds from 3-methyl-2-cyclohexenone.
2) The distillate from sandalwood is one of the oldest and most highly valued fragrances in
perfumery. The natural oil is in short supply and, until recently, synthetic substituents have been
difficult to prepare. The natural oil is in short supply and, until recently, synthetic substitutes
have been difficult to prepare. Polysantol® is the most successful of these substitutes. Its
synthesis in 1984 involved the Aldol condensation shown below.