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Summary: ORIGINAL ARTICLE
doi:10.1111/j.1558-5646.2009.00863.x
GENOME-WIDE INVESTIGATION OF
REPRODUCTIVE ISOLATION IN EXPERIMENTAL
LINEAGES AND NATURAL SPECIES OF
NEUROSPORA: IDENTIFYING CANDIDATE
REGIONS BY MICROARRAY-BASED
GENOTYPING AND MAPPING
Jeremy R. Dettman,1,2,3
James B. Anderson,1
and Linda M. Kohn1
1
Department of Ecology & Evolutionary Biology, University of Toronto, Mississauga, Ontario, L5L 1C6, Canada
2
E-mail: jdettman@uottawa.ca
Received June 9, 2009
Accepted September 28, 2009
Inherent incompatibilities between genetic components from genomes of different species may cause intrinsic reproductive isola-
tion. In evolution experiments designed to instigate speciation in laboratory populations of the filamentous fungus Neurospora,
we previously discovered a pair of incompatibility loci (dfe and dma) that interact negatively to cause severe defects in sexual
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