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Decoding Synteny Blocks and Large-Scale Duplications in Mammalian and Plant Genomes
 

Summary: Decoding Synteny Blocks and Large-Scale
Duplications in Mammalian and Plant Genomes
Qian Peng1,
, Max A. Alekseyev3
, Glenn Tesler2
, and Pavel A. Pevzner1
1
Department of Computer Science and Engineering
qpeng@cs.ucsd.edu
2
Department of Mathematics
University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093
3
Department of Computer Science and Engineering
University of South Carolina, 315 Main St., Columbia, SC 29208
Abstract. The existing synteny block reconstruction algorithms use an-
chors (e.g., orthologous genes) shared over all genomes to construct the
synteny blocks for multiple genomes. This approach, while efficient for a
few genomes, cannot be scaled to address the need to construct synteny
blocks in many mammalian genomes that are currently being sequenced.

  

Source: Alekseyev, Max - Department of Computer Science and Engineering, University of South Carolina

 

Collections: Biotechnology; Computer Technologies and Information Sciences