Home

About

Advanced Search

Browse by Discipline

Scientific Societies

E-print Alerts

Add E-prints

E-print Network
FAQHELPSITE MAPCONTACT US


  Advanced Search  

 
Behavioral/Systems/Cognitive Lateralization of the Human Mirror Neuron System
 

Summary: Behavioral/Systems/Cognitive
Lateralization of the Human Mirror Neuron System
Lisa Aziz-Zadeh,1,2 Lisa Koski,1,5 Eran Zaidel,2,4 John Mazziotta,1,4,5,6,7 and Marco Iacoboni1,3,4
1Ahmanson Lovelace Brain Mapping Center, Neuropsychiatric Institute, 2Department of Psychology, 3Department of Psychiatry and Biobehavioral
Sciences, 4Brain Research Institute, David Geffen School of Medicine, and Departments of 5Neurology, 6Pharmacology, and 7Radiological Sciences,
University of California, Los Angeles, Los Angeles, California 90095
Acorticalnetworkconsistingoftheinferiorfrontal,rostralinferiorparietal,andposteriorsuperiortemporalcorticeshasbeenimplicated
inrepresentingactionsintheprimatebrainandiscriticaltoimitationinhumans.Thisneuralcircuitrymaybeanevolutionaryprecursor
ofneuralsystemsassociatedwithlanguage.However,languageispredominantlylateralizedtothelefthemisphere,whereasthedegreeof
lateralization of the imitation circuitry in humans is unclear. We conducted a functional magnetic resonance imaging study of imitation
of finger movements with lateralized stimuli and responses. During imitation, activity in the inferior frontal and rostral inferior parietal
cortex, although fairly bilateral, was stronger in the hemisphere ipsilateral to the visual stimulus and response hand. This ipsilateral
pattern is at variance with the typical contralateral activity of primary visual and motor areas. Reliably increased signal in the right
superior temporal sulcus (STS) was observed for both left-sided and right-sided imitation tasks, although subthreshold activity was also
observed in the left STS. Overall, the data indicate that visual and motor components of the human mirror system are not left-lateralized.
Thelefthemispheresuperiorityforlanguage,then,mustbehavebeenfavoredbyothertypesoflanguageprecursors,perhapsauditoryor
multimodal action representations.
Key words: motor; sensorimotor; premotor; language; hemisphere; lateralization
Introduction
Several studies indicate a shared representation for the execution

  

Source: Aziz-Zadeh, Lisa - Brain and Creativity Institute & Department of Occupational Science, University of Southern California

 

Collections: Biology and Medicine