Summary: Current Biology 18, 1694­1699, November 11, 2008 ª2008 Elsevier Ltd All rights reserved DOI 10.1016/j.cub.2008.09.043
Report
npr-1 Regulates Foraging
and Dispersal Strategies
in Caenorhabditis elegans
Andrea Gloria-Soria1 and Ricardo B.R. Azevedo1,*
1Department of Biology and Biochemistry
University of Houston
Houston, TX 77204-5001
USA
Summary
Wild isolates of Caenorhabditis elegans differ in their ten-
dency to aggregate on food [1, 2]. Most quantitative variation
in this behavior is explained by a polymorphism at a single
amino acid in the G protein-coupled receptor NPR-1: gregar-
ious strains carry the 215F allele, and solitary strains carry
the 215V allele [2]. Although npr-1 regulates a behavioral syn-
drome with potential adaptive implications, the evolutionary
causes and consequences of this natural polymorphism
remain unclear. Here we show that npr-1 regulates two be-

Source: Azevedo, Ricardo - Department of Biology and Biochemistry, University of Houston

Collections: Biology and Medicine; Environmental Sciences and Ecology