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Intrinsic regulation of the teleost heart is greatly dependent on central venous pressure, which exerts a modulatory role on
 

Summary: Intrinsic regulation of the teleost heart is greatly dependent
on central venous pressure, which exerts a modulatory role on
stroke volume according to the well-known Frank­Starling
mechanism. This mechanism is well characterized in situ
(Farrell et al., 1982; Farrell, 1991) and results from perfused
heart studies have been extrapolated to cardiac function in the
intact animal.
Heart perfusion studies, however, operate at rates well above
the in vivo range of resting heart rate (Altimiras and Larsen,
2000) because the inhibitory cholinergic influence on the heart
is abolished. At the lower in vivo heart rates, the loading
conditions of the heart will differ due to a longer filling time
(Farrell and Jones, 1992), which in turn is expected to increase
venous pressure.
This prediction has not been demonstrated experimentally
due to technical limitations in recording pressure in the sinus
venosus (PSV) in teleosts. Such a study, however, could shed
light on two separate aspects of the cardiac physiology of
teleosts. First, it could explain the shift from vis-ā-fronte atrial
filling to vis-ā-tergo filling (Farrell, 1991). The unique vis-ā-

  

Source: Altimiras, Jordi - Department of Biology, Linköpings Universitet

 

Collections: Environmental Sciences and Ecology