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NET-SYNTHESIS: A software for synthesis, inference and simplification of signal transduction networks
 

Summary: NET-SYNTHESIS: A software for synthesis, inference and
simplification of signal transduction networks
Sema Kachalo 1, Ranran Zhang 2, Eduardo Sontag 3, R´eka Albert 4 and
Bhaskar DasGupta 5
1
Department of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607
2
Penn State Cancer Institute and Integrative Biosciences Graduate Program, Pennsylvania State
University, Hershey, PA 17033
3
Department of Mathematics, Rutgers University, New Brunswick, NJ 08903
4
Departments of Physics and Biology, Pennsylvania State University, University Park, PA 16802
5
Department of Computer Science, University of Illinois at Chicago, Chicago, IL 60607
ABSTRACT
Summary: We present a software for combined synthesis,
inference and simplification of signal transduction networks. The
main idea of our method lies in representing observed indirect
causal relationships as network paths and using techniques from

  

Source: Albert, Réka - Departments of Biology & Physics, Pennsylvania State University

 

Collections: Biology and Medicine