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Transesophageal Magnetic Resonance Imaging of the Aortic Arch and Descending

Summary: Transesophageal Magnetic Resonance Imaging
of the Aortic Arch and Descending
Thoracic Aorta in Patients With Aortic Atherosclerosis
Kendrick A. Shunk, MD, PHD,* Je´ro^me Garot, MD,* Ergin Atalar, PHD, Joa~o A. C. Lima, MD, FACC*
Baltimore, Maryland
OBJECTIVES We sought to determine the feasibility and potential of transesophageal magnetic resonance
imaging (TEMRI) for quantifying atherosclerotic plaque burden in the aortic arch and
descending thoracic aorta in comparison with transesophageal echocardiography (TEE).
BACKGROUND Improved morphologic assessment of atherosclerotic plaque features in vivo is of interest
because of the potential for improved understanding of the pathophysiology of plaque
vulnerability to rupture and progression to clinical events. Magnetic resonance imaging
(MRI) is well suited for atherosclerotic plaque imaging. Performing MRI using a radio
frequency (RF) receiver probe placed near the region of interest improves the signal-to-noise
ratio (SNR).
METHODS High-resolution images of the thoracic aortic wall were obtained by TEMRI in 22 subjects
(8 normals, 14 with aortic atherosclerosis). In nine subjects, we compared aortic wall thickness
and circumferential extent of atherosclerotic plaque measured by TEMRI versus TEE using
a Bland-Altman analysis. Additional studies were performed in a human cadaver with
pathology as an independent gold standard for assessment of atherosclerosis.
RESULTS In clinical and experimental studies, we found similar measurements for aortic plaque


Source: Atalar, Ergin - Department of Electrical and Electronics Engineering, Bilkent University


Collections: Engineering; Biology and Medicine