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Summary: Study of ns and fs pulse laser-induced effects in
biological-tissue models and corneal tissue
Gerardo Romo-Cárdenas¶
, Francisco G. Pérez-Gutiérrez
, Alejandra
Mina-Rosales¶
, Santiago Camacho-López¶
, Guillermo Aguilar
¶
Departamento de óptica, División de física aplicada, CICESE. Carretera Tijuana- Ensenada, Km. 107
Ensenada, Baja California, 22860 México
Mechanical Engineering, University of California, Riverside, CA. 92521 USA.
Abstract. This work presents a study of photo-induced effects in biological-tissue models made
from agar gel and porcine cornea samples. We used a Nd:YAG (5 ns) and a Ti:sapphire (90fs)
lasers to irradiate the samples. The main objective in this study is to understand some aspects of
the interaction between pulsed lasers and biological tissue, of especially interest for us are
vascular and corneal tissues. Our research includes laser heating of vascular-like tissue and laser-
induced cavitation bubble formation in cornea. For the laser heating studies we used tissue
models composed by a single or up to four stack layers made of agar gel (of between 200 and
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