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Available online at www.sciencedirect.com Phytopathogen type III effector weaponry and their plant targets
 

Summary: Available online at www.sciencedirect.com
Phytopathogen type III effector weaponry and their plant targets
Anna Block, Guangyong Li, Zheng Qing Fu and James R Alfano
Phytopathogenic bacteria suppress plant innate immunity and
promote pathogenesis by injecting proteins called type III
effectors into plant cells using a type III protein secretion
system. These type III effectors use at least three strategies to
alter host responses. One strategy is to alter host protein
turnover, either by direct cleavage or by modulating
ubiquitination and targeting the 26S proteasome. Another
strategy involves alteration of RNA metabolism by
transcriptional activation or ADP-ribosylation of RNA-binding
proteins. A third major strategy is to inhibit the kinases involved
in plant defence signaling, either by the removal of phosphates
or by direct inhibition. The wide array of strategies that bacterial
pathogens employ to suppress innate immunity suggest that
circumvention of innate immunity is crucial for bacterial
pathogenicity of plants.
Address
Center for Plant Science Innovation and Department of Plant Pathology,

  

Source: Alfan, James R. - Department of Plant Pathology, University of Nebraska-Lincoln

 

Collections: Biology and Medicine