Home

About

Advanced Search

Browse by Discipline

Scientific Societies

E-print Alerts

Add E-prints

E-print Network
FAQHELPSITE MAPCONTACT US


  Advanced Search  

 
PROTEIN EXPRESSION AND PURIFICATION 13, 4552 (1998) ARTICLE NO. PT980872
 

Summary: PROTEIN EXPRESSION AND PURIFICATION 13, 45­52 (1998)
ARTICLE NO. PT980872
Secretion of Biologically Active Human Interleukin-2
and Interleukin-4 from Genetically Modified
Tobacco Cells in Suspension Culture1
Nancy S. Magnuson,*,2
P. Michael Linzmaier, Raymond Reeves,
Gynheung An,§ Kent HayGlass,Ų
and James M. Lee
*Department of Microbiology, Department of Chemical Engineering, and Department of Biochemistry and Biophysics,
Washington State University, Pullman, Washington 99164-4233; §Department of Life Sciences,
Pohang University of Science and Technology, Kyungbuk, 790-784, Korea; and Ų
Department
of Immunology, University of Manitoba, Winnipeg, ManitobaCanada R3E 0W3
Received October 7, 1997, and in revised form January 9, 1998
increasing awareness of the potential value of
Biologically active human interleukin-2 (IL-2) and transgenic plant systems for the inexpensive produc-
IL-4, key lymphokines involved in immune regulation, tion of high-quality mammalian proteins for pharma-
were produced and secreted into the medium by genet- ceutical and diagnostic purposes. Many of the early
ically modified Nicotiana tabacum cells grown in sus- studies examining the feasibility of using transgenic

  

Source: An, Gynheung - Department of Life Science, Pohang University of Science and Technology

 

Collections: Biotechnology; Biology and Medicine