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glutamate-activated N-methyl-D-aspartate (NMDA) channels have recently been de-
 

Summary: glutamate-activated N-methyl-D-aspartate
(NMDA) channels have recently been de-
scribed (39). Most of our knowledge current-
ly comes from in vitro data, but many of these
(4047). As we discu
ple forms of dendritic
the way neurons integ
complex ways.
axon
soma
dendrite
Fig. 1. Diversity in dendritic excitability. All recordings are from differe
pyramidal neurons, with the recording locations indicated schematically o
(Left) Action potential evoked by distal synaptic stimulation recorded sim
(green trace), soma (blue trace), and apical dendrite 300 m from the so
action potential is initiated in the axon and backpropagates into the so
[modified from (63)]. (Right) Initiation of dendritic Na and Ca2
spikes.
were made simultaneously from the soma and distal dendrites (400 m from
spike, orange trace; 920 m from the soma for the Ca2

  

Source: Alford, Simon - Department of Biological Sciences, University of Illinois at Chicago

 

Collections: Biology and Medicine