Summary: CHM 7200 Organic Structures and Mechanisms Fall Term 2007
Problem Set 10: This problem set is now available at (www.blackboard.wayne.edu). It will be due
in class 14 days (12/14/07) from today (11/30/07). Grades will be administered as follows: 5
(exceptional effort), 4 (complete), 3 (incomplete or inadequate effort), 2 (poor effort), 0
(nonexistent). No late problem sets will be accepted.
1. Problem: The stereoselective synthesis of the macrolide illustrated below was completed by
Jamison, T. et al. Please give the mechanism for each transformation and comment on the