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Effect of vacuum and thermal shock on laser treatment of Trichophyton rubrum (toenail fungus)
 

Summary: Effect of vacuum and thermal shock on laser treatment of
Trichophyton rubrum (toenail fungus)
Guillermo Aguilar1
, Feng Sun1
, Pierre Carlier2
, Erica Young1
, David Hennings3
, F. Javier González4
1. Department of Mechanical Engineering, University of California Riverside, USA
2. Ecole Nationale Supérieure D'Ingénieurs de Caen & Centre de Recherche, France
3. CoolTouch, Inc, Roseville, California, USA
4. CIACyT, Universidad Autónoma de San Luis Potosí, México
ABSTRACT
The eradication of Trichophyton rubrum has been attempted via laser irradiation because it could result advantageous
relative to current clinical therapies. Anticipating that the necessary thermal effects could unintentionally damage the
underlying toe dermal layer, we have explored two auxiliary approaches: (a) laser irradiation under vacuum pressure,
with and without water dousing and, (b) cooling followed by laser heating (thermal shock). The rationale is that at low
pressures, the temperature necessary to achieve water evaporation/boiling is significantly reduced, thus requiring lower
fluences. Similarly, a thermal shock induced by cooling followed by laser irradiation may require lower fluences to
achieve fungus necrosis. For all experiments presented we use a Cooltouch, model CT3 plus, 1320 nm laser to irradiate

  

Source: Aguilar, Guillermo - Department of Mechanical Engineering, University of California at Riverside

 

Collections: Engineering