Summary: Current Biology, Vol. 14, 1018­1024, June 8, 2004, 2004 Elsevier Ltd. All rights reserved. DOI 10.1016/j.cub.2004.05.050
Caenorhabditis elegans-Based Screen
Identifies Salmonella Virulence Factors
Required for Conserved Host-Pathogen Interactions
ferred each day to fresh plates to avoid losing track of
these initial worms in the morass of progeny. This is
tedious and time consuming, greatly reducing the num-
ber of killing assays that can be performed. We therefore
tested whether temperature-sensitive C. elegans glp-4
Jennifer L. Tenor,1
Beth A. McCormick,2
Frederick M. Ausubel,3
and Alejandro Aballay1,
*
1
Department of Molecular Genetics
and Microbiology
Duke University Medical Center
Durham, North Carolina 27710 worms, in which germ cells are blocked in mitotic pro-
phase and fail to proliferate and differentiate into gonads2

Source: Ausubel, Frederick M. - Department of Genetics, Harvard University

Collections: Biology and Medicine