| | |
Summary: 107
The Anterior Cingulate Cortex
The Evolution of an Interface between
Emotion and Cognition
JOHN M. ALLMAN,a ATIYA HAKEEM,a JOSEPH M. ERWIN,b
ESTHER NIMCHINSKY,c AND PATRICK HOFd
aDivision of Biology, California Institute of Technology, Pasadena,
California 91125, USA
bDivision of Neurobiology, Behavior, and Genetics, Bioqual, Rockville,
Maryland 20850, USA
cHoward Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor,
New York 11724, USA
dNeurobiology of Aging Laboratories, Mount Sinai School of Medicine, New York,
New York 10029, USA
ABSTRACT: We propose that the anterior cingulate cortex is a specialization of
neocortex rather than a more primitive stage of cortical evolution. Functions
central to intelligent behavior, that is, emotional self-control, focused problem
solving, error recognition, and adaptive response to changing conditions, are
juxtaposed with the emotions in this structure. Evidence of an important role
for the anterior cingulate cortex in these functions has accumulated through
|
