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Preparation and Biological Evaluation of Copper-64Labeled Tyr3 Octreotate Using a Cross-Bridged Macrocyclic Chelator
 

Summary: Preparation and Biological Evaluation of Copper-64­Labeled Tyr3
-
Octreotate Using a Cross-Bridged Macrocyclic Chelator
Jennifer E. Sprague,1
Yijie Peng,2
Xiankai Sun,1
Gary R. Weisman,2
Edward H. Wong,2
Samuel Achilefu,1
and Carolyn J. Anderson1
1
Mallinckrodt Institute of Radiology, Washington University School
of Medicine, St. Louis, Missouri; and 2
Department of Chemistry,
University of New Hampshire, Durham, New Hampshire
ABSTRACT
Purpose: Somatostatin receptors (SSTr) are expressed on
many neuroendocrine tumors, and several radiotracers have
been developed for imaging these types of tumors. For this
reason, peptide analogues of somatostatin have been well char-

  

Source: Anderson, Carolyn J. - Department of Molecular Biology and Pharmacology, Washington University in St. Louis

 

Collections: Biology and Medicine