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Molecular Cell Distinct Roles of Chromatin-Associated

Summary: Molecular Cell
Distinct Roles of Chromatin-Associated
Proteins MDC1 and 53BP1
in Mammalian Double-Strand Break Repair
Anyong Xie,1 Andrea Hartlerode,1 Manuel Stucki,2,3,9 Shobu Odate,1 Nadine Puget,1,10 Amy Kwok,1
Ganesh Nagaraju,1 Catherine Yan,5,6,7 Frederick W. Alt,4,5,6,7 Junjie Chen,8 Stephen P. Jackson,2,3
and Ralph Scully1,*
1Department of Medicine, Harvard Medical School and Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston,
MA 02215, USA
2The Wellcome Trust/Cancer Research UK Gurdon Institute
3Department of Zoology
Cambridge University, Tennis Court Road, Cambridge CB2 1QN, UK
4Howard Hughes Medical Institute
5Department of Genetics
Harvard Medical School, Boston, MA 02115, USA
6The Children's Hospital, Boston, MA 02115, USA
7The Immune Disease Institute, Boston, MA 02115, USA
8Department of Therapeutic Radiology, Yale University School of Medicine, 333 Cedar Street, New Haven,
CT 06520, USA


Source: Alt,, Frederick - Immune Disease Institute, Harvard University


Collections: Biology and Medicine