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Summary: · Gray matter densities in CBP were determined
VBM analysis using the SPM 99 package. A
nonparametric comparison was performed
between a 17 CBP and matched controls (panel 1)
·fMRI activity for spontaneous pain in CBP (n=13)
·and thermal induced pain in CBP (n=10) and
normals (n=14) were determined using the FSL
software package . Events that delineates high-low
pain in all pain conditions were derived from the
ongoing pain ratings of subjects and convolved
with a gamma function to search for brain activity
using a GLM model. group average activity was
done using the random effect analysis and all
appropriate controls were subtracted. The activity
maps were transformed into talairach space and
loaded on the 152-standard brain(panel 2).
·Brain areas showing significant activity in the 3
pain conditions or areas showing brain
atrophy(shown in red) were selected to examine
their interrelationships.
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