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THE EMERGENT STRUCTURE OF THE DROSOPHILA WING A Dynamic Model Generator
 

Summary: THE EMERGENT STRUCTURE OF THE DROSOPHILA WING
A Dynamic Model Generator
Alberto Silletti
Department of Information Engineering, University of Padova, Via Gradenigo 6A, Padova, Italy
silletti@dei.unipd.it
Angelo Cenedese
Department of Engineering and Management, University of Padova, Vicenza, Italy
angelo.cenedese@unipd.it
Alessandro Abate
Department of Aeronautics and Astronautics, Stanford University, Stanford (CA), U.S.A.
aabate@stanford.edu
Keywords: Structure detection, Graphical model, Random walk, Drosophila wing, Morphogenesis.
Abstract: Drosophila melanogaster is a model organism in genetics thanks to the compactness of its genome and its
relative simplicity. Recently, certain developmental patterns in Drosophila have been studied by mathematical
models, with the aim of gaining deeper and quantitative insight into the morphogenesis of this insect. There
is a need for accurate dynamical of the epithelial cell structure and organization within the fly wing, to further
the understanding of a phenomenon known as planar cell polarity. The present study tackles the problem of
retrieving such a salient structure using classical tools of dynamical system theory embedded with network
and graph concepts. On the one hand the goal is to provide a visual detection and representation of the cell
packaging that is accurate and fine. Particular care is also put in obtaining a model of this structure, whose

  

Source: Abate, Alessandro - Faculty of Mechanical, Maritime and Materials Engineering, Technische Universiteit Delft

 

Collections: Engineering