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Nucleus accumbens responses to painful aversive and rewarding stimuli change in chronic pain
 

Summary: Nucleus accumbens responses to painful aversive and rewarding
stimuli change in chronic pain
M. N. BALIKI1, H. L. FIELDS2, A. APKARIAN1
SFN 2009
Chicago
74.15/X22
INTRODUCTION
· There is growing evidence that neurons in the
circuitry classically associated with reward and
reward prediction can encode aversive signals and
elicit aversive behaviors
1Dept Physiol, Northwestern Univ., Chicago, IL; 2Departments of Neurol. and Physiol., UCSF, San Francisco, CA
Brain activity maps for perception of
thermal pain
1 Differences in time course of NAc BOLD
signal between CBP and controls
3 5 Functional connectivity of NAc
elicit aversive behaviors.
·Here we use fMRI to examine brain activity in
healthy humans and in chronic back pain (CBP)

  

Source: Apkarian, A. Vania - Department of Physiology, Northwestern University

 

Collections: Biology and Medicine