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Spatial and temporal dynamics of rabies virus variants in big brown bat populations across Canada: footprints
 

Summary: Spatial and temporal dynamics of rabies virus variants
in big brown bat populations across Canada: footprints
of an emerging zoonosis
SUSAN A. NADIN-DAVIS,* YUQIN FENG,* DELPHINE MOUSSE, ALEXANDER I. WANDELER*
and STE´ PHANE ARIS-BROSOU
*Centre of Expertise for Rabies, Ottawa Laboratory (Fallowfield), Canadian Food Inspection Agency, Ottawa, Ontario, Canada,
Department of Biology, University of Ottawa, Ottawa, Ontario, Canada, Department of Mathematics and Statistics,
University of Ottawa, Ottawa, Ontario, Canada
Abstract
Phylogenetic analysis of a collection of rabies viruses that currently circulate in Canadian
big brown bats (Eptesicus fuscus) identified five distinct lineages which have emerged
from a common ancestor that existed over 400 years ago. Four of these lineages are
regionally restricted in their range while the fifth lineage, comprising two-thirds of all
specimens, has emerged in recent times and exhibits a recent demographic expansion
with rapid spread across the Canadian range of its host. Four of these viral lineages are
shown to circulate in the US. To explore the role of the big brown bat host in
dissemination of these viral variants, the population structure of this species was
explored using both mitochondrial DNA and nuclear microsatellite markers. These data
suggest the existence of three subpopulations distributed in British Columbia, mid-
western Canada (Alberta and Saskatchewan) and eastern Canada (Quebec and Ontario),

  

Source: Aris-Brosou, Stéphane - Department of Biology, University of Ottawa

 

Collections: Biology and Medicine