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http://jbiol.com/content/8/9/83 Vaknin et al.: Journal of Biology 2009, 8:83 Transposable elements (TEs) have contributed a wide range of
 

Summary: http://jbiol.com/content/8/9/83 Vaknin et al.: Journal of Biology 2009, 8:83
Abstract
Transposable elements (TEs) have contributed a wide range of
functional sequences to their host genomes. A recent paper in
BMC Molecular Biology discusses the creation of new trans-
cripts by transposable element insertion upstream of retrocopies
and the involvement of such insertions in tissue-specific post-
transcriptional regulation.
Among the many factors that contribute to the diversity of
genome structure and organization in different eukaryotes
are transposable elements, which comprise a large fraction
of many eukaryotic genomes. It is now well established
that the activities of these elements represent a major
evolutionary force that has shaped the genes and genomes
of many species, contributing a wide range of functional
sequences. Some transposable elements encode the enzyme
reverse transcriptase, which as well as being involved in the
proliferation and movement of the element within the
genome, occasionally reverse transcribes a mature spliced
cellular mRNA and inserts the DNA copies (cDNAs) into

  

Source: Ast, Gil - Department of Molecular Genetics and Biochemistry, Tel Aviv University

 

Collections: Biology and Medicine