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Summary: Blood-stage Plasmodium infection induces CD8 T
lymphocytes to parasite-expressed antigens,
largely regulated by CD8 dendritic cells
Rachel J. Lundie*
, Tania F. de Koning-Ward*§
, Gayle M. Davey*, Catherine Q. Nie*
, Diana S. Hansen*,
Lei Shong Lau*
, Justine D. Mintern¶
, Gabrielle T. Belz*
, Louis Schofield*, Francis R. Carbone¶
, Jose A. Villadangos*
,
Brendan S. Crabb*
**, and William R. Heath*¶
*Walter and Eliza Hall Institute of Medical Research and Cooperative Research Centre for Vaccine Technology, Parkville, Victoria 3050, Australia;
Departments of Medical Biology and ¶Microbiology and Immunology, University of Melbourne, Parkville, Victoria 3010, Australia; The Burnet Institute,
Melbourne, Victoria 3004, Australia; and §School of Medicine, Deakin University, Waurn Ponds, Victoria 3217, Australia
Communicated by Emil R. Unanue, Washington University School of Medicine, St. Louis, MO, July 12, 2008 (received for review February 19, 2008)
Although CD8 T cells do not contribute to protection against the
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