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Tissue-specific alternative splicing of BK channel transcripts in Drosophila
 

Summary: Tissue-specific alternative splicing of BK channel
transcripts in Drosophila
J. Y. Yu
, A. B. Upadhyaya
and
N. S. Atkinson,*

Section of Neurobiology, The University of Texas at Austin,
Austin, TX, and
Department of Biology, University of South
Florida, East Fowler Avenue, Tampa, FL, USA
*Corresponding author: N. S. Atkinson, The University of Texas
at Austin, Section of Neurobiology, 1 University Station C0920,
Austin, TX 78712-0248, USA. E-mail: nigela@mail.utexas.edu
BK-type calcium-activated potassium channels are large
conductance channels that respond to changes in intra-
cellular calcium and membrane potential. These chan-
nels are used in a wide variety of cell types and have
recently been linked to drug sensitivity and tolerance.
In both Drosophila and mammals, BK channels are

  

Source: Atkinson, Nigel - Section of Neurobiology, Division of Biological Sciences, University of Texas at Austin

 

Collections: Biology and Medicine