Summary: DOI 10.1007/s00702-002-0722-7
J Neural Transm (2002) 109: 1309­1334
Brain chemistry reflects dual states of pain and anxiety in
chronic low back pain
I. D. Grachev1,2
, B. E. Fredrickson3
, and A. V. Apkarian4
Departments of 1
Anesthesiology,
2
Neuroscience and Physiology, and
3
Orthopedic Surgery, SUNY Upstate Medical University, Syracuse, NY, and
4
Department of Physiology, Northwestern University Medical School,
Chicago, IL, USA
Received November 12, 2001; accepted February 12, 2002
Published online June 28, 2002; © Springer-Verlag 2002
Summary. The neurobiology of the interaction between pain and anxiety is
unknown. The present study examined interrelationships between: regional

Source: Apkarian, A. Vania - Department of Physiology, Northwestern University

Collections: Biology and Medicine