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Summary: Abstract- The assumption that cerebrospinal fluid (CSF) inflow
and outflow is an essential element of an intracranial
compartment (IC) model has been recently questioned [3]. The
idea proposed in [3] that the free displacement of the CSF is one
of the significant sources of the brain compliance is supported
in this paper by computing an overall system compliance with a
novel algorithm. The compliance obtained using the proposed
method is shown to be in the same order of the magnitude as
that obtained using the traditional intrusive infusion test
technique.
Keywords - Intracranial pressure, lumped model, venous flow
I. INTRODUCTION
Intracranial pressure (ICP) has been traditionally
considered a function of the CSF production rate (If) and the
outflow resistance (Rout) [1]. Lumped circuit models of the
IC have thus considered the CSF compartment as a current
source and resistance [2]. This concept has been challenged
as a result of dynamic MRI studies that suggest an
alternative role of CSF [3]. These studies suggest that the
dynamic movement of CSF is the primary IC compliance
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