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COMPREHENSIVE SDSU-UCSD CANCER CENTER PARTNERSHIP NCI Grants #U54 CA132384 and #U54 CA132379
 

Summary: COMPREHENSIVE SDSU-UCSD CANCER CENTER PARTNERSHIP
NCI Grants #U54 CA132384 and #U54 CA132379
Project Period: 9/1/2008 8/31/2013
Pilot Projects
Funded Projects 2009
OPTIMIZED NANOPARTICLE VACCINES FOR PROSTATE CANCER
Minority Institution Co-Leader Cancer Center Co-Leader
Douglas Grotjahn, Ph.D.
Professor
Dept. of Chemistry
Boris R. Minev, M.D.
Associate Professor
Dept. of Family & Preventative Medicine
Abstract
Among the body's potential defenses are white blood cells called cytotoxic T lymphocytes
(CTL). CTL can recognize and kill cancer cells, but only if they see complexes of protein
fragments (peptides) attached to special molecules on the surface of the cancer cells. Several
recent reports demonstrated the presence of anti-tumor CTL in blood from patients with brain
tumors. It was also found that a protein called surviving exists in most prostate cancers.
We found recently several small pieces (peptides) derived from the protein surviving on the

  

Source: Abagyan, Ruben - School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego

 

Collections: Biology and Medicine