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Cell, Vol. 118, 175186, July 23, 2004, Copyright 2004 by Cell Press Heritable Integration of kDNA Minicircle Sequences
 

Summary: Cell, Vol. 118, 175­186, July 23, 2004, Copyright 2004 by Cell Press
Heritable Integration of kDNA Minicircle Sequences
from Trypanosoma cruzi into the Avian Genome:
Insights into Human Chagas Disease
round amastigote form by binary fission in various tis-
sues of the mammalian host. Mammals belonging to
several classes (marsupials, edentates, lagomorphs, ro-
dents, carnivores, primates, and chiropterans) are hosts
for T. cruzi. Birds are refractory to T. cruzi infection
Nadjar Nitz, Clever Gomes, Ana de CaŽ ssia Rosa,
Marian R. D'Souza-Ault, Francisco Moreno,
Liana Lauria-Pires, Rubens J. Nascimento,
and Antonio R.L. Teixeira*
Chagas Disease Multidisciplinary
(reviewed in Teixeira [1987]).Research Laboratory
American trypanosomiasis infections span an exten-Faculty of Medicine
sive geographical area between 42 N in the UnitedUniversity of BrasiŽlia
States to 43 S in Argentina. Human Chagas disease isBrasiŽlia
considered the most significant parasitic disease inBrazil
Latin America. It is estimated that 16­18 million people

  

Source: Arnold, Jonathan - Nanoscale Science and Engineering Center & Department of Genetics, University of Georgia

 

Collections: Biotechnology