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Brn-3c (POU4F3) regulates BDNF and NT-3 promoter activity R. Lee Clougha
 

Summary: Brn-3c (POU4F3) regulates BDNF and NT-3 promoter activity
R. Lee Clougha
, Richa Suda
, Noa Davis-Silbermanb
, Ronna Hertzanob
,
Karen B. Avrahamb
, Matthew Holleyc
, Sally J. Dawsona,*
a
Molecular Audiology, Department of Immunology and Molecular Pathology, UCL Centre for Auditory Research, Windeyer Institute
of Medical Sciences, University College London Medical School, The Windeyer Building, Cleveland Street, London W1T 4JF, UK
b
Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
c
Department of Biomedical Sciences, University of Sheffield, Addison Building, Sheffield S10 2TN, UK
Received 9 September 2004
Available online 25 September 2004
Abstract
Brn-3c is a transcription factor necessary for maturation and survival of hair cells in the inner ear. Mutations in Brn-3c are asso-

  

Source: Avraham, Karen - Department of Human Genetics and Molecular Medicine, Tel Aviv University

 

Collections: Biology and Medicine