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Staphylococcal Biofilm Exopolysaccharide Protects against Caenorhabditis elegans
 

Summary: Staphylococcal Biofilm Exopolysaccharide
Protects against Caenorhabditis elegans
Immune Defenses
Jakob Begun1,2
, Jessica M. Gaiani3
, Holger Rohde4
, Dietrich Mack5
, Stephen B. Calderwood6,7
, Frederick M. Ausubel1,2
,
Costi D. Sifri3,6*
1 Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, 2 Department of Genetics, Harvard Medical School,
Boston, Massachusetts, United States of America, 3 Division of Infectious Diseases and International Health, University of Virginia Health System, Charlottesville, Virginia,
United States of America, 4 Institut fušr Medizinische Mikrobiologie, Virologie und Hygiene, Universitaštsklinikum Hamburg-Eppendorf, Hamburg, Germany, 5 Medical
Microbiology and Infectious Diseases, The School of Medicine, University of Wales Swansea, Swansea, United Kingdom, 6 Division of Infectious Diseases, Massachusetts
General Hospital, Boston Massachusetts, United States of America, 7 Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts,
United States of America
Staphylococcus epidermidis and Staphylococcus aureus are leading causes of hospital-acquired infections that have
become increasingly difficult to treat due to the prevalence of antibiotic resistance in these organisms. The ability of
staphylococci to produce biofilm is an important virulence mechanism that allows bacteria both to adhere to living and

  

Source: Ausubel, Frederick M. - Department of Genetics, Harvard University

 

Collections: Biology and Medicine